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1 or even cure, if all sites of disease can be ablated.
2 ion of progesterone receptor was genetically ablated.
3 lives different regions of the neuraxis were ablated.
4 as well as the adenosine transporter, can be ablated.
5 ctin and classical pathways were genetically ablated.
6 riatum or hippocampus where CK2alpha is also ablated.
7 eason 7 PTEN-intact tumor is almost entirely ablated.
8 (p-nitrophenyl acetate, pNPA) is effectively ablated.
10 cation of a small molecule SK1 inhibitor all ablated 2's effect on phenotype, consistent with its des
13 immunomodulatory nanoparticles (IMPs), which ablate a specific subset of hematogenous monocytes (hMos
14 d by nerve injury or inflammation in mice by ablating a group of adult spinal neurons defined by deve
15 versal of the pairing in [Formula: see text] ablates A1913 movement regardless of whether the interac
16 yocytes from mouse models expressing phospho-ablated (AAA) and phosphomimetic (DDD) cMyBP-C as well a
17 reserved in mice lacking lymphocytes and was ablated after depletion of eosinophils or treatment with
18 fundamental frequency (lambda = 1,064 nm) to ablate Ag and graphite composite target submerged in eth
20 ere, using a zebrafish model, we genetically ablate all embryonic tendon cells and find complete rege
23 hen unmodified mPBMCs were transplanted into ablated allogeneic recipients, all recipients expired by
24 KO of the endogenous TCR in T cells strongly ablated alloreactivity in comparison with TCR-expressing
28 4Ralpha(-/-) mice, residual eosinophilia was ablated, and susceptibility to chronic adult Brugia mala
30 of depths; the nail material adjacent to the ablated area was rendered porous in appearance presumabl
31 at day 2 showed small white densities in the ablated areas, which appeared to be small intraepithelia
32 itor cells that co-express Sox2 and Bmi1 are ablated, as we observed that ageing in mice started with
34 attice-tip catheter could safely and rapidly ablate atrial fibrillation using either a combined RF/PF
36 Mutating the bulge sequence to 5'-ACCCC-3' ablates base stacking in the loop and globally reorients
38 specific enhancer harboring AD-risk variants ablated BIN1 expression in microglia, but not in neurons
40 0-fold higher than the IC50 were required to ablate both ADP-ribosylation and XRCC1 chromatin binding
41 y was additionally indicated by NOS blockade ablating both the positive vascular effects of adropin i
42 iddle Aged and Old SMFAs; (ii) eNOS blockade ablating both the positive vascular effects of adropin i
45 neic antigen can be effectively targeted and ablated by adoptive transfer of antigen-specific CD8(+)
46 -fat diet treated with metformin was largely ablated by AMPK deficiency under the conditions examined
47 53 pathway in MRT cells, and sensitivity was ablated by CRISPR-Cas9-mediated inactivation of TP53.
48 ellular lineages, second wave follicles were ablated by diptheria toxin treatment of Lgr5-DTR-EGFP mi
52 ptor-alpha (ESR1) expression was essentially ablated by p95HER2 expression, in a manner recapitulated
58 ryl plate standard down to 0.6 and 0.4 ng of ablated carbon, respectively (standard deviation 0.25 pe
61 etic stem cells that have been engineered to ablate CD33 expression using genomic engineering methods
62 without adaptive immunity, we simultaneously ablated CD8(+) and B cells with cytotoxic monoclonal ant
64 Using this integrative approach, we have ablated cells in zebrafish embryos with both spatial and
67 K), which inhibits molecular clock function, ablates circadian differences and reduces muscle growth.
69 e transporter gene (DAT) promoter control to ablate Cnr2 gene in midbrain DA neurons of DAT-Cnr2 cond
70 calization to the blood-spinal cord barrier, ablated CNS edema, and led to accelerated functional rec
71 construction method for LA-ICP-MS imaging by ablating consecutive layers of a biological specimen wit
73 (Ca(V)-abetalator), an E3 ubiquitin ligase, ablated currents from diverse HVACCs reconstituted in HE
74 , including sG alone, mG alone, mutants with ablated CX3C, and G with enhanced packaging into vector
75 utralizing antibody (NAb) responses, whereas ablating CX3C drastically reduced the RSV NAb response.
76 onstrate that therapeutic inhibition of mTOR ablates cytotoxic-resistant CSCs, and they suggest that
78 Inactivation of all four RAB3 genes nearly ablated DCV exocytosis, and re-expression of RAB3A resto
80 with substitution of all tryptophan residues ablating dimerization and self-renewal function complete
81 ic cell transplantation (HCT), often fail to ablate disease-initiating MDS HSCs, and thus have low cu
87 ction and glucose homeostasis by genetically ablating eIF4G1 specifically in beta-cells in vivo (beta
88 ction and glucose homeostasis by genetically ablating eIF4G1 specifically in beta-cells in vivo (beta
90 mouse models in which Twist1 was selectively ablated either in infiltrating, inflammatory macrophages
91 oid bodies with diphtheria toxin efficiently ablated endocardial cells, which significantly attenuate
93 he application of picosecond laser pulses to ablate endoluminal bowel lesions demonstrates significan
94 ective ER downregulators (SERDs) are able to ablate ER and thus, theoretically, to prevent survival o
95 RASER by adeno-associated virus selectively ablated ErbB-hyperactive cancer cells while sparing ErbB
97 Homozygosity for an N-terminal truncation ablates expression and causes widespread erythrokeratode
101 Here, we show that female mice genetically ablated for cyclin B3 are viable-indicating that the pro
102 nterestingly, murine N2a neuroblastoma cells ablated for endogenous PrP expression were susceptible t
103 antages are not specific to the model system ablated for our demonstration, namely neurites in the ne
105 we report that tribbles homologue 2 (TRIB2) ablates forkhead box O activation and disrupts the p53/M
107 rom the left ventricular summit (LVS) can be ablated from the great cardiac vein and remote endocardi
108 of the nodoventricular AP were successfully ablated from within the proximal coronary sinus (CS) gui
110 s pharmacologically inhibited or genetically ablated, Gbetagamma can bind to PLCbeta but does not eli
111 tibodies, (2) with mice that had selectively ablated germinal center-derived IgG production, or (3) t
114 eloped a novel mouse model that specifically ablates hindbrain GR to ascertain its role in behaviour,
115 thermore, group cross-reactive (GR)-antibody-ablated homologous fusion peptide-mutated (FP)-VLPs cons
116 and showed that the transplantation of CD33-ablated HSPCs with CD33-targeted immunotherapy leads to
118 ng1(S365A/S365A) mutant mouse that precisely ablates IFN-dependent activities while preserving IFN-in
119 elopmental timepoint at which podocalyxin is ablated (immature vs. mature podocytes) has a profound e
120 Pseudo-reentrant carousels were incorrectly ablated in 5 cases having been misinterpreted as LR.
122 replicating osteoblast lineage cells can be ablated in an inducible manner using ganciclovir (GCV).
126 , in response to inflammasome activation, is ablated in FABP4/aP2(-/-) macrophages, as well as in FAB
127 erreactivity to methacholine was essentially ablated in M pneumoniae-infected, OVA-sensitized animals
128 air cells were conditionally and selectively ablated in mature, transgenic mice where the human dipht
129 sole E2 SUMO-conjugating enzyme, Ube2i, was ablated in mouse oocytes beginning in primordial follicl
130 ransgenic mice in which Cxcr2 is selectively ablated in oligodendroglia upon treatment with tamoxifen
131 re.Socs3 (f/f) mice, in which SOCS3 has been ablated in osteocytes, have high trabecular bone volume
133 tumor progression, TMPRSS13 was genetically ablated in the oncogene-induced transgenic MMTV-PymT tum
135 nd surfactin treatment of the virus inoculum ablated infection in vivo Finally, similar cyclic lipope
136 methylation of the H-bond accepting nitrogen ablates inhibitor potency, confirming the role of the K7
137 We report that, after a chemical lesion that ablates inner retinal neurons, regenerated retinal bipol
138 (V)1.2 alpha(1C) subunits with (1) mutations ablating interaction between alpha(1C) and beta-subunits
139 llow (depth ~ 700 nm) inclined guiding track ablated into the polydimethylsiloxane-coated surface of
140 sive, image-guided procedure that is able to ablate intracranial tissue with submillimetre precision.
142 pancreatic cancer pathology, we genetically ablated it in an autochthonous murine model (KrasG12D; P
143 Due to the lower pulse energy required to ablate, it is more precise than a solid-state nanosecond
144 ents with intellectual disability and autism ablate its catalytic activity or ankyrin-G interaction.
146 induced loss of Ser(474) phosphorylation by ablating its upstream kinase mTORC2, have implicated Ser
148 methods of treatment for cervical cancer can ablate lesions, preventing metastatic disseminations and
153 sonance-ultrasound fusion imaging to focally ablate low-intermediate-grade tumors within the prostate
157 pectroscopy (LIBS) technique is optimized to ablate material from the surface of produced rubber shee
164 g the normal cortical critical period; while ablating MET signaling leads to early closure of critica
166 eficient C57BL/6 mice, thereby conditionally ablating MHC class I-restricted Ag presentation in targe
167 infusions prevented neuron loss in pericyte-ablated mice despite persistent circulatory changes.
168 ve cycle progression, but RFRP-activated and ablated mice exhibited apparently normal fertility.
172 rodynamic simulation of optical vortex pulse-ablated microcone structures on silicon (Si) substrates.
174 rated a mouse model in which we specifically ablated Mig-6 in uterine epithelial cells using Sprr2f-c
177 otherapy (SDRT), a disruptive technique that ablates more than 90% of human cancers, operates a disti
178 ox/flox) and Advillin(Cre/+) mice completely ablates MORs in dorsal root ganglion neurons and reduces
179 ion of canonical Wnt signaling in betaglycan ablated MSCs, and the addition of recombinant Wnt5a to M
181 c cells secrete Fam3a, and exposure of Stat3-ablated muscle stem cells to recombinant Fam3a in vitro
182 omimetic mutant of GAPVD1, but not a phospho-ablating mutant, were able to rescue defects in transfer
185 rs on resident cells blunts kidney fibrosis, ablates NF-kappaB signaling, and lessens matrix depositi
188 , we used intersectional genetic strategy to ablate NPY(+) noradrenergic neurons and/or adrenal chrom
190 acking interactions of the photosensitizers, ablating of the tumors without relapse by taking advanta
191 erated new mouse genetic models to selective ablate one of POMC-neuron enriched transcription factors
192 ome function in the developing mouse limb by ablating one of its essential components, U11 small nucl
194 and increased adult DG neurogenesis, whereas ablating or chronically inhibiting Ocn-Cre(+) dDG neuron
196 sease is that the radiation dose required to ablate pancreatic cancer exceeds the tolerance of the ne
197 g, and histological analysis showed that the ablated Paneth cells are replaced by enteroendocrine and
199 ue of Neuron, Groman et al. (2019) precisely ablate pathways between the OFC, amygdala, and nucleus a
200 ion as well as treatment with SFK inhibitors ablate pDC (but not conventional DC) responses both in v
202 responses that were similar to those of the ablated population, which is also consistent with networ
204 calorimetry measurements-specific mutations ablated preQ(1) binding, but most aberrant binding effec
205 itive Prlr antagonist, and a mouse line with ablated Prlr in the Nav1.8 sensory neuronal population,
207 s showed disrupted flight orientation and an ablated proboscis extension response to the natural stim
209 to its regular sites along chromosomes while ablating Protein Phosphatase 4 had the opposite effect.
210 lacking PIEZO1 in innate immune cells showed ablated pulmonary inflammation in the context of bacteri
211 naptic plasticity during an EE experience by ablating RARalpha signaling induced runaway Hebbian plas
213 n of tumor margins and adjuvant therapies to ablate remaining tumor tissues are needed during surgica
214 tations of the transmembrane lysine residues ablate retrograde sorting and subject Snc1 to quality co
215 nt and Hippo-independent regulation of YAP1, ablating rhabdomyosarcoma cell growth in vitro and trend
216 different ages by conditionally labeling and ablating RMs populations in several transgenic lines.
217 procedure in male FosLacZ-transgenic rats to ablate selectively Fos-expressing PLC neurons that were
218 mising feasibility and safety to selectively ablate senescent cells from tissues, a therapeutic modal
226 destly decreased primary site growth without ablating spontaneous metastasis to the lung and moderate
228 ed cyclical scheme involving collect-analyze-ablate steps to obtain continuous near real-time measure
229 blation and DREADD technology to selectively ablate, stimulate, and inhibit RFRP neurons to interroga
231 ress this, we used CRISPR/Cas9 technology to ablate SYNGAP1 protein expression in neurons derived fro
233 Genetic ablation of beta-arrestin2 markedly ablates tau pathology and rescues synaptic plasticity de
237 A new study establishes genetic tools to ablate tendon progenitor cells in zebrafish larvae, find
238 ined the consequences of locally and acutely ablating terminal Schwann cells (tSCs) at the adult mous
239 ode ultrasound array (DMUA) system to safely ablate the CB in vivo in a spontaneously hypertensive ra
240 nt genetic models targeting cilia completely ablate the compartment, making it difficult to uncouple
242 yed multiplex genome editing to specifically ablate the expression of the highly polymorphic HLA-A/-B
243 but these inhibitors could also efficiently ablate the growth of drug-insensitive stem-like cells as
245 we used the Cre-loxP system to conditionally ablate the murine huntingtin gene (Htt(flx)) in cells ex
246 hat disrupted the pTRS1 interaction with PKR ablated the ability of pTRS1 to antagonize PKR activatio
247 otein in vitro, this modification completely ablated the activity of LLO, and this inhibitory effect
249 with an IFNAR-neutralizing antibody after MI ablated the interferon response and improved left ventri
250 Deficiency of KCNQ2-containing M-channels ablated the M(1)R-induced enhancement of M-current in DG
251 Using a conditional targeting approach, we ablated the major CLP gene Irf6 only in the late embryon
253 ins, deletion of even a single PPIase domain ablates the ability of SurA to prevent OmpT aggregation.
255 We observed that the removal of Munc18-2 ablates the release of alpha, dense, and lysosomal granu
257 has never been supported experimentally and ablating the cell repeatedly failed to eliminate all rap
258 ns to triclosan and plumbagin by effectively ablating the change in intracellular redox potential of
259 Aicardi-Goutieres syndrome demonstrate that ablating the cyclic GMP-AMP synthase gene abolishes the
260 cell activity, with toxicophore modification ablating the desired effects of these compounds on cance
262 udied its role during tissue regeneration by ablating the function of one of its components, Eyes abs
264 at the collected particles were continuously ablated; the time for complete ablation of 193 ng of suc
266 mpulsive ethanol consumption, we selectively ablated these neurons in adult male and female C57BL/6 J
267 d lincRNA), Rubie and Atcayos We genetically ablated these six lincRNAs in mouse, which suggested gen
268 and that electrically silencing or optically ablating these cells suppresses coordinated electrical a
269 g cardiomyocytes and examined the effects of ablating these endogenously cycling cardiomyocytes on my
275 lity, whereas adducin-1 depletion completely ablated thrombin-induced barrier disruption without comp
276 ting PKD are limited because PC2 function is ablated throughout the cell in existing model systems.
277 wever, how to leverage cellular signaling to ablate TMPRSS2-ERG oncoprotein for PCa treatment remains
278 n which one or both GTPases were genetically ablated to investigate the role of RalGTPases in the Sch
280 ISG) that we previously have demonstrated to ablate translation of HIV proteins based on the virus's
282 In 13 (33%; 95% CI: 18, 47) of 40 completely ablated tumors, intrahepatic tumor recurrence was observ
284 in mutant in which the G3BP2-binding site is ablated, unlike that of wild-type alpha-parvin, in alpha
285 and thus DA biosynthesis, was conditionally ablated using either floxed Th mice or viral-based CRISP
286 ere randomized in 8 dogs with 2 superior PVs ablated using one technology and 2 inferior PVs ablated
288 f Chat within the T cell compartment in mice ablated vasodilation in response to infection, impaired
289 co-injection of norrin with VEGF completely ablated VEGF-induced BRB permeability to Evans Blue-albu
291 Deletions that encroached upon PE1 and PE2 ablated virus growth and identified additional adjacent
292 hesion molecules and leukocyte adhesion were ablated when disrupting sympathetic nerves, demonstratin
293 ast Aha-type co-chaperones to act in vivo is ablated when the N terminal NxNNWHW motif is removed.
296 ot proceed when proliferating IA6+ cells are ablated with Mitomycin C, and injection of a single IA6+
297 ute phase of the disease when microglia were ablated with PLX5622, whereas other cytokines (eg, inter
298 r loss of both proteins to greatly reduce or ablate XRCC1 chromatin binding following H2O2 treatment.
299 f acute and neuropathic pain, we selectively ablated Y1R-expressing interneurons with intrathecal adm
300 ogen diluted in argon was reacted with laser ablated Zn atoms to produce the NCZnCN and NCZnZnCN cyan