ライフサイエンスコーパス: abnormality

1 termates, which was suggestive of a vascular abnormality.

2 xed views, and this stage was named stuck in abnormality.

3 lly before Abeta surpasses the threshold for abnormality.

4 isability and signature brain and congenital abnormalities.

5 isplayed histopathologic alveolar and airway abnormalities.

6 vir (LPV/r) is associated with steroidogenic abnormalities.

7 in of epithelial cells, indicative of cortex abnormalities.

8 be a key strategy to prevent these diabetic abnormalities.

9 L hTau, and is associated with mitochondrial abnormalities.

10 nd various biochemistry and blood cell count abnormalities.

11 vity or GABA signaling corrects the observed abnormalities.

12 communication deficits and other behavioral abnormalities.

13 ss immature neuronal synapses and behavioral abnormalities.

14 of mTOR signaling can result in neurological abnormalities.

15 nd reversal of depression associated circuit abnormalities.

16 ng showed reappearance of the repolarization abnormalities.

17 gnosis despite having accompanying metabolic abnormalities.

18 cyte transdifferentiation or long-term liver abnormalities.

19 ion, and its absence leads to several myelin abnormalities.

20 egy in preventing subclinical leaflet-motion abnormalities.

21 ter TOF repair with concomitant haemodynamic abnormalities.

22 ed histological characteristics of fundus AF abnormalities.

23 hibitory control and affective and cognitive abnormalities.

24 s are not due to morphological or structural abnormalities.

25 born babies with developmental brain and eye abnormalities.

26 al-tDCS, indicating reversal of pathological abnormalities.

27 stent with development of underlying cardiac abnormalities.

28 ing the potential for progression of cardiac abnormalities.

29 ion of left ventricular regional wall motion abnormalities.

30 e synaptic dysfunction and social behavioral abnormalities.

31 arked leaflet redundancy, and repolarization abnormalities.

32 on and aneurysms, arrhythmia, and conduction abnormalities.

33 n of the placenta and placental pathological abnormalities.

34 ala, and putamen as demonstrating convergent abnormalities.

35 are independent risk factors for radiologic abnormalities.

36 PPAR-alpha signaling and rectifies metabolic abnormalities.

37 th histopathological verification of imaging abnormalities.

38 ts in at least some of the hira-1 late-onset abnormalities.

39 fractionation even in the absence of voltage abnormalities.

40 authors for characteristic retinal vascular abnormalities.

41 contributing to autism-associated behavioral abnormalities.

42 malities, and with myocardial injury and TTE abnormalities.

43 , schizophrenia involves networks with broad abnormalities.

44 ly, and 5.21 (1.50, 18.07; p=0.009) for gait abnormalities.

45 c prolongation and/or typical repolarization abnormalities, 121 were diagnosed as affected based on c

46 drusen (23.0% versus 2.1%), retinal pigment abnormalities (26.6% versus 7.3%), exudative macular deg

47 microhemorrhages (11.3%), 22 with perfusion abnormalities (47.7%), and three with restricted diffusi

48 s well as disorder-specific brain structural abnormalities across 6 major psychiatric disorders.

49 sociated with the development of any cardiac abnormality (adjusted odds ratio 2.59, 95% confidence in

50 g 6 months, history of glaucoma, and corneal abnormalities affecting IOP measurement.

51 cutive patients with additional haemodynamic abnormalities after tetralogy of Fallot (TOF) repair, wh

52 urally derived extracellular vesicle protein abnormalities also reveal a range of later amplification

53 set and progression of cancer, developmental abnormalities and adaptive potential.

54 Fmr1-KO rats showed gamma power abnormalities and behavioral hyperactivity that were con

55 self-administration produced cardiopulmonary abnormalities and changes in alpha4, alpha3, and beta2 n

56 ed in the pathogenesis of neurodevelopmental abnormalities and cognitive deficits commonly observed i

57 ents have increased prevalence of conduction abnormalities and compromised sinoatrial node function w

58 dinal associations between reward processing abnormalities and depression.

59 uch disruption can predispose the hybrids to abnormalities and disease that decrease the overall fitn

60 ependently associated with interstitial lung abnormalities and findings suspicious for interstitial l

61 Conclusion Bowel abnormalities and gallbladder bile stasis were common fi

62 To understand the transcriptional abnormalities and heterogeneity associated with myofiber

63 ng one causing PCCA2, result in sphingolipid abnormalities and impaired cell growth that are correcte

64 Brain abnormalities and intellectual disability are commonly o

65 evere symptoms, including neurodevelopmental abnormalities and microcephaly.

66 re to different doses of BPA induced uterine abnormalities and molecular changes in a rat model.

67 ion of TFEB is the main driver of the kidney abnormalities and mTORC1 hyperactivity in a mouse model

68 ic conditions characterised by developmental abnormalities and reduced organismal growth in addition

69 differential diagnosis of suspicious breast abnormalities and reducing unnecessary biopsies.

70 Ultimately, this generates chromosomal abnormalities and the release of nuclear DNA into the cy

71 rstand the mechanisms underlying these brain abnormalities and to explore interventions to mitigate t

72 sized that DS mice recapitulate craniofacial abnormalities and upper airway obstruction of human DS a

73 n 1 year there was stabilization of T2/FLAIR abnormalities, and after 2 years there was complete reso

74 About 40%-50% of patients have kidney abnormalities, and frequently display multicystic, dyspl

75 ence rate [IR]), prevalence of anal squamous abnormalities, and human papillomavirus (HPV) 16.

76 en p15 and p16 expression, centrosome number abnormalities, and melanoma progression in cell lines de

77 ntellectual disability, seizures, behavioral abnormalities, and various skeletal and structural anoma

78 or soft exudates, intraretinal microvascular abnormalities, and venous beading, agreement was moderat

79 l injury, with myocardial injury without TTE abnormalities, and with myocardial injury and TTE abnorm

80 Anatomic variations, a lymphatic pathologic abnormality, and interventional access routes were ident

81 These results suggest that gamma power abnormalities are a translatable biomarker among species

82 These abnormalities are accompanied with chronic inflammation,

83 symptoms, clinical signs, and/or laboratory abnormalities are attributed to changes in the numbers o

84 Furthermore, cognitive abnormalities are established core characteristics of sc

85 as refractive errors, strabismus, and fundus abnormalities are frequent in children with FASD and per

86 rylation reliant the extent of mitochondrial abnormalities are identified.

87 al models that can be used to examine clonal abnormalities are limited.

88 these commonly observed findings, and these abnormalities are more apparent during exercise testing,

89 Dopaminergic abnormalities are often seen after TBI, but patients usu

90 Thus, it appears that WM abnormalities are present early in youth with persistent

91 In mood disorders, psychomotor and sensory abnormalities are prevalent, disabling, and intertwined

92 our results suggest that the dendritic spine abnormalities are primary developmental defects in the L

93 S cardiac enlargement and that CS-associated abnormalities are reversible, and provide evidence of in

94 e of ISR activation prevented the behavioral abnormalities as well as increased cortical neural activ

95 sulforaphane affects many of the biochemical abnormalities associated with ASD.

96 impaired PPAR-alpha expression or metabolic abnormalities associated with GSD-Ia.

97 y underpowered to characterize neuroanatomic abnormalities associated with psychosis in 22q11DS, and/

98 iate COVID-19 pneumonia from other causes of abnormalities at chest radiography.

99 A1 cleavage is a novel mechanism for cristae abnormalities because of both C10 mutation and C2/C10 lo

100 ata of this study provide evidence of immune abnormalities before motor onset of disease.

101 or the missense mutation show no behavioural abnormalities but do have sex-specific deficits in body

102 rn of greater ipsilateral than contralateral abnormalities, but less marked than those in patients wi

103 with widespread white matter microstructural abnormalities, but the functional effects of these abnor

104 coma, particularly when associated with iris abnormalities, cataract, or retinal detachment.

105 Endocardial abnormalities cause reduced cardiomyocyte proliferation

106 to identify clinically relevant copy number abnormality (CNA) profiles.

107 muscle fiber defects, neuromuscular junction abnormalities, compromised motor performance, and premat

108 with a series of in vitro and in vivo immune abnormalities consistent with lymphocyte hyperactivity.

109 Moreover, the 22q11DS calcium abnormality could also be restored by application of ant

110 ptable and scalable, able to quantify occult abnormalities, derive mechanistic insights, and define a

111 due to probe design differences, with focal abnormalities detectable using one technique not observa

112 Whether these abnormalities develop into more recognizable disease sta

113 The loss of Anks6 causes ciliary abnormalities, ductal plate remodeling defects and perip

114 al biopsies to rule out anatomic and mucosal abnormalities, esophageal high-resolution manometry to r

115 V-1 infection reproduced the ILC and NK cell abnormalities ex vivo.

116 xelwise statistics showed that the diffusion abnormalities for both fractional anisotropy and mean di

117 s that included left ventricular wall motion abnormalities, global left ventricular dysfunction, left

118 Metabolic abnormalities have been widely reported in depressed pat

119 Cerebrovascular abnormalities have emerged as a preclinical manifestatio

120 risk factors and network-level neuroimaging abnormalities have shown effects on cognitive performanc

121 dysregulated adaptive immunity, coagulation abnormalities, hemorrhage, and multiorgan failure with u

122 cardial injury had more electrocardiographic abnormalities, higher inflammatory biomarkers and an inc

123 king (HR 3.42, 95% CI 1.40-8.45), and thymic abnormalities (HR 1.82, 95% CI 0.91-3.67).

124 s demonstrated ultrastructural mitochondrial abnormalities (hyperplasia, hypertrophy, and crystalline

125 eased interictal heart rate and heart rhythm abnormalities (i.e. sinus pause and sinus arrhythmias) w

126 systems in depression towards circuit level abnormalities impacting function across multiple brain r

127 tially correct hemodynamic responses and EEG abnormalities, improve cognitive deficits, revert autist

128 cross-disorder analysis of brain structural abnormalities in 6 psychiatric disorders based on effect

129 dy was to investigate the underlying genetic abnormalities in a 25-year-old woman affected with MNGIE

130 nd induced patient neurons displayed similar abnormalities in action potential repolarization.

131 chronic leptin administration reverses these abnormalities in adipose tissue, but the underlying mech

132 tment ameliorates this phenotype, except for abnormalities in apoptosis and basal autophagy.

133 erebellar circuit dysfunction and behavioral abnormalities in ASD.

134 In contrast, Cbs(-/-) mice show no abnormalities in blood coagulation.

135 tly associated with cortical and subcortical abnormalities in both mass-univariate and multivariate p

136 nancy, has been increasingly associated with abnormalities in brain function and behaviour of the off

137 es of internalizing youths differentiated by abnormalities in brain structure, function, and white ma

138 invertebrate model organisms, but currently abnormalities in CDK19 are not known to be associated wi

139 d the hypothesis that important eye movement abnormalities in cerebellar disorders (i.e., ataxias) co

140 CKD is associated with abnormalities in cerebral blood flow, cerebral neurochem

141 Although biochemical abnormalities in common causes of CKD-mineral and bone d

142 To examine whether abnormalities in connectome organization precede psychos

143 e-compulsive disorder, a condition linked to abnormalities in corticobasal ganglia networks.

144 ttered loss of myoepithelial cells are other abnormalities in dacryoadenosis.

145 ize the upper airway as well as craniofacial abnormalities in Dp(16)1Yey (Dp16) mice.

146 Abnormalities in each of cardiac metabolism, physiologic

147 however, studies have demonstrated continued abnormalities in fat and/or lipid storage in PLWH treate

148 These results provide evidence that abnormalities in GPHYSD1 patients with this mutation are

149 e aneuploidies, we show that sub-chromosomal abnormalities in human blastocysts arise from mitotic er

150 ral regions, with additional regions showing abnormalities in individuals.

151 Our results demonstrate that early genetic abnormalities in interneurons can interact with postnata

152 he primary pacemaker of the human heart, and abnormalities in its structure or function cause sick si

153 nalyses showed disorder-specific gray matter abnormalities in left thalamus and bilateral insula asso

154 ically evaluate how postnatal ELS relates to abnormalities in miRNA expression and functions from bot

155 cardiomyopathy is defined as the presence of abnormalities in myocardial structure and function that

156 Nonperfusion area, SSPiM, and microvascular abnormalities in OCTA images were evaluated using a Heid

157 M2) and DPN.PurposeTo assess skeletal muscle abnormalities in participants with DM2 with or without D

158 dysfunction, reward processing, and salience abnormalities in people at clinical high risk of psychos

159 omputational theories have hypothesized that abnormalities in prior beliefs and/or the precision-weig

160 s sought to characterize thalamic structural abnormalities in psychosis and a neurodevelopmental coho

161 racting protein kinase (Hipk)-induced growth abnormalities in response to a high sugar diet.

162 echanisms underlying gamma-band ASSR network abnormalities in schizophrenia.

163 Emerging data suggest that abnormalities in Schwann cells (SCs) may cause neuropath

164 nding the bidirectional relationship between abnormalities in sleep and anxiety-related brain pathway

165 ls for up to 1 year revealed no reproducible abnormalities in survival, motor function, or neurodegen

166 d impair astrocyte bioenergetics, leading to abnormalities in synaptic neurotransmission and cognitiv

167 lled in a study of cerebrospinal fluid (CSF) abnormalities in syphilis that was conducted at the Univ

168 ardiac cell culture model for MFS, revealing abnormalities in the behavior of MFS CMs that are relate

169 final model recognized regional wall motion abnormalities in the cross-validation and external valid

170 s that suggest that type 1 diabetes includes abnormalities in the exocrine pancreas that may induce e

171 in A1 compared with A2 and less wall motion abnormalities in the jeopardized myocardium versus both

172 brillation (AF) often arises from structural abnormalities in the left atria (LA).

173 ex congenital heart disease characterized by abnormalities in the left ventricle, associated valves,

174 Variations or abnormalities in the physiological cortisol levels contr

175 Abnormalities in the synchondroses affect the developmen

176 Recent neuroimaging findings point to abnormalities in the thalamus of patients with SCZ, incl

177 human brain during embryogenesis and of how abnormalities in this process lead to neurological disea

178 remic toxins in cerebral and neurobehavioral abnormalities in three rat models of CKD, we induced CKD

179 ith previous observations related to network abnormalities in TLE and expand on the notion of underly

180 In addition, to investigate underlying local abnormalities in white matter by assessing the tract-spe

181 uture studies should seek to characterize WM abnormalities in younger individuals and follow individu

182 ted imaging (DWI) was used to investigate WM abnormalities in youth at-risk for psychosis.

183 percontractility is a key pathophysiological abnormality in hypertrophic cardiomyopathy, and a major

184 HS appears to be a primary abnormality in the pilosebaceous-apocrine unit.

185 nsgene in Mecp2R294X mice rescued phenotypic abnormalities including early death and demonstrated tha

186 ce, leading to the identification of similar abnormalities including fewer satellite cells, fewer div

187 t periodontitis is associated with metabolic abnormalities including non-alcoholic fatty liver diseas

188 ), severe postnatal progressive neurological abnormalities (including abnormal neonatal cry, hypotoni

189 requencies, and post-natal mice have FA-like abnormalities, including bone marrow failure.

190 erging human pathogen that causes congenital abnormalities, including microcephaly and eye disease.

191 ad given birth, and no infants with apparent abnormalities, including microcephaly, have been identif

192 that had an increased incidence of metabolic abnormalities, including type 2 diabetes, low HDL, high

193 espite the emerging evidence of neurological abnormalities induced by dystrophin loss.

194 syndrome CATIFA (cleft lip, cataract, tooth abnormality, intellectual disability, facial dysmorphism

195 Microaneurysms, intraretinal microvascular abnormalities (IRMAs), and neovascularization appeared t

196 However, the nature of these abnormalities is unclear because most focus on responses

197 SD), but the neural basis underlying sensory abnormality is not completely understood.

198 lvular leakage (PVL) and onset of conduction abnormalities leading to permanent pacemaker implantatio

199 gulation of their activities through genetic abnormalities leads to pathologies such as developmental

200 Histological abnormalities, left ventricular hypertrophy, and left ve

201 Cardiac structural abnormalities, left ventricular hypertrophy, or concentr

202 The most frequent MRI findings were signal abnormalities located in the medial temporal lobe in 16

203 ew studies address the possibility that PTSD abnormalities may be confounded by comorbid depression.

204 The delayed root formation and periodontal abnormalities may be related to defects in RUNX2-depende

205 Abnormalities may be seen on posterior segment examinati

206 nergy-conserving states promotes contractile abnormalities, morphological and metabolic remodeling, a

207 ients with MLII present with severe skeletal abnormalities, multisystemic symptoms, and early death;

208 vents, consisting of asymptomatic laboratory abnormalities (n = 4), hepatitis and colitis (n = 2).

209 tes kindlin-2 expression, leading to spindle abnormalities not only in the SH-SY5Y cell line, but als

210 insights into the cellular and immunological abnormalities observed in patients and suggests new ther

211 s is lost and phenocopies the PNN structural abnormalities observed in tenascin-R knockout brains.

212 bably the underlying cause for developmental abnormalities observed upon dElys depletion.

213 of the reproductive system is highlighted by abnormalities observed upon the loss or mutation of this

214 nset anatomical, physiologic, and behavioral abnormalities of C. elegans.

215 viously showed to ameliorate other lysosomal abnormalities of cystinotic cells.

216 ce also exhibited insulin resistance-related abnormalities of energy metabolism, such as lower total

217 Abnormalities of one carbon, glutathione and sulfide met

218 Abnormalities of or reductions in GABAergic interneurons

219 reconstitution of phenotypic and functional abnormalities of T(FH)-B cell axis.

220 Inherited and acquired abnormalities of TET2 occur in 0.39% of PAH cases.

221 Background Abnormalities of the central lymphatic system (CLS) are

222 udies in preterm infants report white matter abnormalities of the corpus callosum (CC) as an importan

223 White matter abnormalities of the human brain are implicated in typic

224 the microbiota and on disease risk; reported abnormalities of the microbiota in children with JIA; me

225 21 (6%; 95% CI 4-9) of 336 showed fetal abnormalities, of which 12 (4%; 2-6) were adjudicated as

226 The application of deep learning to detect abnormalities on CT examinations using video pretraining

227 n stiffness measurements were corrected with abnormalities on neuroimaging and histopathology using m

228 HMS) is a validated tool that captures motor abnormalities on routine neurologic examination and whic

229 s, controlling for gestational age, sex, and abnormality on structural MRI, DWMA volume was an indepe

230 Sixty-nine percent of participants showed an abnormality on the MHMS, with 27% classified as severe.

231 ribose uptake can be indicative of metabolic abnormalities or tumorigenesis.

232 clinical and/or laboratory data, pancreatic abnormalities, or inadequate quality of MRI studies.

233 Outer retinal abnormalities persisted on OCT in patients after resolut

234 ng skeletal, connective tissue, and vascular abnormalities, poor postinfection lung healing, and subs

235 n a unilateral occlusion, creates behavioral abnormalities presented by brain and eye histopathology.

236 ntal disability, muscular hypotonia, feeding abnormalities, recurrent fever episodes, and infantile s

237 for schizophrenia-spectrum disorders display abnormalities related to motivational salience, or the a

238 imaging (DTI) may enable detection of muscle abnormalities related to type 2 diabetes mellitus (DM2)

239 y beneficial effect in preventing behavioral abnormalities relevant, yet not specific, to the disorde

240 er, the underlying mechanisms inducing these abnormalities remain to be elucidated.

241 alities, but the functional effects of these abnormalities remain unclear.

242 r, the basis of these sympathetic-associated abnormalities remains unclear.

243 ut the molecular driver(s) of this metabolic abnormality remains obscure.

244 Four of six animals showed abnormalities reminiscent of human disease in brain magn

245 ression patterns which precede morphological abnormalities reported at later neurodevelopmental stage

246 omavirus and display focal histopathological abnormalities resembling those of human papillomavirus (

247 nin T), systemic involvement, and electrical abnormalities (right bundle branch block/low voltages) w

248 er eyelid meiboscores (P = .012), lid margin abnormality scores (P = .0059), and meibum quality (P =

249 The most common abnormalities seen were gait (54%), followed by coordina

250 Clinical and topographic abnormalities similar to keratoconus were observed in 14

251 the WFS1 gene may be responsible for corneal abnormalities similar to keratoconus.

252 immune cells may be the drivers of systemic abnormalities such as autoimmune disease.

253 to antibiotic-treated mice caused behavioral abnormalities such as psychomotor hyperactivity, impaire

254 Pulmonary vascular abnormalities such as vessel enlargement and regional mo

255 ination of the placenta by a pathologist for abnormalities, such as infection or maternal vascular ma

256 Radiographic and laboratory abnormalities, such as lymphopenia and elevated lactate

257 atients with VPS16 and VPS41 showed vacuolar abnormalities suggestive of impaired lysosomal function.

258 akness, hyporeflexia, and electrophysiologic abnormalities suggestive of neuropathy were frequently o

259 ormalize their ECG after detraining, but the abnormalities tend to recur with resumption of training.

260 udostratified airway epithelium with similar abnormalities than original in vivo phenotype.

261 opathic cystinosis CKD patients have mineral abnormalities that are distinct from those in CKD stemmi

262 rlie the synaptic dysfunction and behavioral abnormalities that bear similarities to autism.

263 ve led to identification of specific genetic abnormalities that contribute to malignancy.

264 or the hippocampus would produce behavioral abnormalities that could be attributed to astrocyte bioe

265 the onset of subclinical pulmonary perfusion abnormalities that could herald the development of signi

266 reased prevalence of major echocardiographic abnormalities that included left ventricular wall motion

267 CD56(-) monocytes from MDS patients, several abnormalities that may be related to the increased susce

268 detect disease in the absence of structural abnormality, thereby enhancing diagnostic sensitivity, b

269 on was associated with similar neuroanatomic abnormalities to idiopathic schizophrenia.

270 with COVID-19 may help to characterize nerve abnormality, to identify site and severity of nerve dama

271 erosis (MS), knowledge about how spinal cord abnormalities translate into clinical manifestations is

272 mate the recognition of regional wall motion abnormalities using temporal and spatial information fro

273 cant association was observed between fundus abnormalities, VA, or IOP with hematologic parameters (P

274 r-objectively diagnosed diffuse white matter abnormality volume (DWMA; diffuse excessive high signal

275 attenuated inversion recovery (FLAIR) signal abnormality volume, Gaussian-normalized relative cerebra

276 ooled prevalence estimates of elevated liver abnormalities were as follows: aspartate transaminase 15

277 These abnormalities were attributed to aberrant release of the

278 Fetal or neonatal abnormalities were classified as a major birth defect ac

279 Regional wall abnormalities were defined by experienced physiologists

280 Very few abnormalities were detected by classical diffusion MRI m

281 Foetuses with structural brain abnormalities were excluded from the study.

282 Lipid abnormalities were identified as total cholesterol >200

283 Chronic pulmonary disease and gait abnormalities were more common among adults with HTLV-1

284 Fundus abnormalities were observed in 8 patients (10.1%), consi

285 None of these abnormalities were observed in liver- or muscle-specific

286 Congenital abnormalities were observed only among the fetuses carri

287 Chest radiographic and CT abnormalities were predominately bilateral in 14 of 14 (

288 VID-19 who underwent TTE, cardiac structural abnormalities were present in nearly two-thirds of patie

289 ols aged up to 75 years who had no biomarker abnormalities were recruited from the Sant Pau Initiativ

290 Major aneurysm-related morphological abnormalities were revealed by CTA in 103 patients (17.2

291 Basal ganglia abnormalities were seen in four other patients (5%).

292 Such abnormalities were seen in the younger (1-2 months) as w

293 The frequency of fundus abnormalities were similar in diabetic and non-diabetic

294 ware quantification of the extent of CT lung abnormality were predictors of intensive care unit admis

295 S-CoV-2) infection but only mild respiratory abnormalities who developed an akinetic mutism attributa

296 osed as affected based on combination of ECG abnormalities with positive genotyping (QTc, 482+/-35 ms

297 cGVHD had additional abnormalities, with increased activated T cells, naive h

298 acterized by ocular, auditory, and cutaneous abnormalities, with major complications of infection and

299 en with HIV have a high incidence of cardiac abnormalities, with only a minority being transient.

300 These data demonstrate an intrinsic abnormality within CD8 T cells primed by rat RHV infecti