ライフサイエンスコーパス: abortive infection

1 ectors to mediate bacteriophage immunity via abortive infection.

2 ounts, suggesting that many cells go through abortive infection.

3 the basis of its active assembly leading to abortive infection.

4 ystems that operate via immunity rather than abortive infection.

5 immunity against bacteriophages by inducing abortive infection.

6 as reverse transcription (RT), resulting in abortive infection.

7 s induces substantial cell death, leading to abortive infection.

8 on were evident in infected pDCs, indicating abortive infection.

9 DNA injection, restriction/modification, and abortive infection.

10 oci and resistance to bacteriophages through abortive infection.

11 inefficiently completed, which results in an abortive infection.

12 on with the viral capsid protein, leading to abortive infection.

13 ing genomic DNA in a form of cell suicide or abortive infection.

14 g the phage genes responsible for triggering abortive infection.

15 ga2, provide robust antiviral protection via abortive infection.

16 thesizing viral RNA and proteins, suggesting abortive infection.

17 identifies mechanisms that may underpin its abortive infection.

18 E then disrupts the BTP1 lytic cycle through abortive infection.

19 ction against the temperate phage SPbeta via abortive infection.

20 ial sites of infection, potentially limiting abortive infections.

21 e the possibility of SARS-CoV-2 seronegative abortive infections.

22 f a complementary RNA target, culminating in abortive infection(1).

23 ially enriched in healthcare workers who had abortive infections(1), and in household contacts protec

24 ication systems (R-M) (Tock & Dryden, 2005), abortive infection (Abi) (Chopin et al, 2005), Argonaute

25 iction and modification (R/M) system and the abortive infection (Abi) mechanism, AbiR, that impedes b

26 Bacterial abortive infection (Abi) systems are 'altruistic' cell d

27 nts (DGRs), retrons, CRISPR-Cas systems, and Abortive Infection (Abi) systems in prokaryotes.

28 ding restriction-modification systems (R-M), abortive infection (Abi), Argonaute-based interference,

29 A commonly used phage resistance strategy is abortive infection (Abi), in which the infected cell com

30 rabbit cells tested, vMyxM062-KO conducts an abortive infection, although it initiates viral DNA repl

31 fection likely stems from factors other than abortive infection and caspase-1-dependent pyroptosis in

32 arge fraction of infected cells dies through abortive infection and has a half-life of approximately

33 (poly-dA) accumulation in the cell, driving abortive infection and population-level immunity.

34 HIV-1-induced abortive infection and pyroptotic cell death were also n

35 HIV-2 Vpx gene product, thereby diminishing abortive infection and pyroptotic cell death within byst

36 the productive growth cycle, resulting in an abortive infection and radically restricting viral repli

37 ative estimates of parameters characterizing abortive infection and support the notion that abortive

38 pression to establish quiescence and prevent abortive infection and that the virus usurps a Daxx-medi

39 Here we discuss the general causes of abortive infections and provide specific examples from t

40 ently, retron toxin-antitoxin systems act as abortive infection anti-phage defence systems, in line w

41 Such abortive infections are likely common in nature and can

42 vidual cell and supports growing evidence of abortive infection by some types of CRISPR-Cas systems.

43 ears has revealed an incredible diversity of abortive infections by DNA and RNA viruses in various an

44 Finally, we describe how abortive infections can be applied to basic and clinical

45 susceptible and permissive cell populations, abortive infections can be detected in subpopulations of

46 We also discuss how abortive infections can have critical roles in shaping h

47 The persistence of abortive infections caused by CRPV offers advantages for

48 These cells undergo abortive infection characterized by the cytosolic accumu

49 of RabA2 resulted in an increased number of abortive infection events, including bursting of ITs and

50 tion/modification system LlaI and carries an abortive infection gene, abiA.

51 e tissue die through pyroptosis triggered by abortive infection, i.e., infection of resting T cells i

52 e inner membrane as a widespread strategy of abortive infection in bacterial phage defense.

53 Vaccinia virus undergoes abortive infection in CHO cells, which is characterized

54 To investigate the role of abortive infection in driving CD4(+) T cell loss in vivo

55 This confirms the importance of abortive infection in driving T cell depletion.

56 at does not express NS2 and NS4 underwent an abortive infection in HAE-ALI.

57 replication-competent MCMV vector underwent abortive infection in human DC; this was accompanied by

58 ecimens from atypical lesions may produce an abortive infection in limited cell lines and a cytopathi

59 us mutants and other poxviruses that undergo abortive infection in mammalian cells are receiving spec

60 HCMV carries out an abortive infection in mink lung cells, but it was able t

61 e that Hna limits phage spread by initiating abortive infection in response to a phage protein.

62 During a single round of an abortive infection in the absence of inducer, the synthe

63 ubules near masses of dense viroplasm during abortive infection in the absence of the A17 or A14 prot

64 cells, indicating that SAMHD1 contributes to abortive infection in these cells.

65 We have previously identified abortive infections in HeLa cells infected with herpes s

66 tap35-infected Sf9 cells during an otherwise abortive infection induced by apoptosis.

67 ly evolved from AbiF, which is encoded by an abortive infection-linked gene that is stably associated

68 Notably, antiviral defense capitalizes on an abortive infection mechanism, whereby infected cells die

69 nity against bacteriophage lambda through an abortive infection mechanism.

70 hesis that type VI effectors evolved from an abortive infection module encompassing an anticodon nucl

71 These findings suggested that abortive infection occurred at the stage of viral DNA re

72 ellular viral replication centers results in abortive infection of DCs with both VV and MVA.

73 we analyzed the role of both proteins in the abortive infection of human HeLa cells with the poxvirus

74 by replication in hepatocytes and not by the abortive infection of Kupffer cells and the following cy

75 Recent studies have highlighted how abortive infection of resting and thus nonpermissive CD4

76 levels, and that SAMHD1 expression promotes abortive infection of this important memory cell subset.

77 defense strategy: that both restriction and abortive infections operate during coevolution with phag

78 ves the infected cell but rather enforces an abortive infection pathway leading to infected cell deat

79 as systems (that is, types III and VI) cause abortive-infection phenotypes by activating indiscrimina

80 ortive infection and support the notion that abortive infection represents an important mechanism und

81 DNA replication but consistently triggers an abortive infection response in which infected cells carr

82 is launched first, but then, if it fails, an abortive infection response leading to PCD/dormancy via

83 Immunity results in an abortive infection response, where infected cells do not

84 motor stator proteins MotAB to activate the abortive infection response.

85 ression of a toxic repetitive protein and an abortive infection response.

86 nown RTs (UG) and are closely related to the Abortive Infection system (Abi) RTs.

87 ing CRISPR-Cas, restriction-modification and abortive infection systems (1-4) .

88 se genes additionally activate non-R-M-based abortive infection systems encoded by prophages.

89 uins and classical lactococcal/streptococcal abortive infection systems.

90 Bacterial abortive-infection systems limit the spread of foreign i

91 e system is a genetically engineered form of abortive infection that traps and eliminates phages pote

92 om the literature to illustrate the range of abortive infections that have been reported.

93 In its abortive infection, the gamma(1)34.5 null mutant induces

94 pe V single-effector nuclease Cas12a2 drives abortive infection through non-specific cleavage of doub

95 des a structural basis for this mechanism of abortive infection to achieve population-level immunity,

96 Many anti-phage systems function by abortive infection to kill a phage-infected cell, raisin

97 However, the contribution of abortive infection to T cell loss and how quickly aborti

98 e adsorption inhibition, injection blocking, abortive infection, toxin-antitoxin, and CRISPR-Cas syst

99 s the demise of bystander CD4 T cells due to abortive infection, viral DNA sensing, inflammasome asse

100 AcNPV was lower than that of AcNPV; however, abortive infection was not found.

101 rity of CD4(+) T cells in tissue die through abortive infection, where the accumulation of incomplete

102 igger effector-mediated toxicity, leading to abortive infection, which is associated with phosphoribo

103 ing cells have been reported only to exhibit abortive infections with vaccinia virus (VACV).