ライフサイエンスコーパス: absence

1 resence of rifampicin and deleterious in its absence.

2 site-binding energetics of Syt1 both in the absence and presence of Ca(2+).

3 processive Pol delta-DNA-PCNA complex in the absence and presence of FEN1.

4 B is activated by multiple factors in QseC's absence and prior functions ascribed to QseBC may origin

5 mplement activation in the liver, and in its absence, AP activation leads to chronic inflammation and

6 tardation Protein (FMRPO), the protein whose absence causes FXS, differentially modulates HCN channel

7 variation data sets, we found that presence/absence changes rather than quantitative changes in TF g

8 consistent predictor of disease presence (or absence) compared to alpha-diversity indices.

9 roups according to the presence (group A) or absence (group B) of preexisting cardiopulmonary disease

10 nnel coupling in mesenteric arteries and its absence in pulmonary arteries.

11 Absence (in Sele(-/-) hosts) or therapeutic blockade of

12 Absence, loss and malfunction of Schwann cells or their

13 linicians to the possibility of OAC-ICH, but absence of a blood-fluid level is not useful in excludin

14 light irradiation at room temperature in the absence of a catalyst.

15 With increasing drug resistance and the absence of a clinically available vaccine, there is an u

16 ive elimination at benzylic positions in the absence of a cocatalytic Lewis acid.

17 However, in the absence of a complete molecular understanding of the mec

18 s to care globally is challenging due to the absence of a comprehensive database of healthcare facili

19 Absence of a conserved basic residue and presence of aci

20 In the absence of a correlate(s) of protection against human tu

21 cid system, providing an explanation for the absence of a cyclic voltammetry peak corresponding to PC

22 Our results indicate not only the absence of a ferroelectric critical thickness but also e

23 However, here we established the absence of a functional GM-CSF receptor in murine nocice

24 nt response element reporter gene due to the absence of a Keap1-binding motif.

25 the human host have remained elusive in the absence of a model for the viral entry site.

26 In the absence of a pharmacological cure, finding the most sens

27 rent tubulin concentrations, the presence or absence of a polymerization catalyst or tubulin-binding

28 that gauge this compactness are the presence/absence of a radial-node in the valence-orbital and rela

29 munity to external magnetic disturbance, the absence of a stray field or the resonance in the teraher

30 The absence of a tether in the acetal unit considerably outp

31 In the absence of a universal influenza A vaccine or treatment,

32 In the absence of AC6, activation of AMPK mobilizes Kif19a into

33 In the absence of ACE2, single-RBD-up conformations dominated a

34 Presence/absence of AD-like pathology was donor-specific (reprodu

35 e that changes-of-mind can occur even in the absence of additional evidence after the initial decisio

36 in social (acoustic) cues of density in the absence of additional food can induce similar life-histo

37 helical filament-like fibres in vitro in the absence of additives such as heparin.

38 adipose tissue had ongoing lipolysis in the absence of adipocyte triglyceride lipase (ATGL).

39 istence, but persister cells can form in the absence of all hipBA operons or spoT, indicating that mu

40 ergic responses can be triggered even in the absence of allergens due to Pavlovian conditioning to a

41 th common co-pathologies in the presence and absence of Alzheimer's disease neuropathology.

42 In the absence of an effective treatment, direct cell transplan

43 as present beginning at ~110 ms, even in the absence of an explicit task to think about the relations

44 chieved when G(s) is coupled to GPR52 in the absence of an external agonist.

45 understanding is further underscored by the absence of animal models in the case of human-restricted

46 In the absence of anti-EBV agents, however, therapeutic options

47 T-cell responses during HIV infection in the absence of antiretroviral treatment, we compared HLA-B*5

48 this sequence targeted to microvilli in the absence of any direct interaction with the other IMAC co

49 uration with gas-permeable walls, but in the absence of any installed source of gas.

50 th the optical properties of the cornea, the absence of any large-scale changes following treatment c

51 present a suitable therapeutic option in the absence of any other therapeutic approaches.

52 ve sigma factor sigma(I) is essential in the absence of aPBPs.

53 ath mechanism that fully compensates for the absence of apoptosis in antiviral host defense.

54 o-optics to visualize the appearance, in the absence of applied field, of a permanent electric polari

55 However, the absence of assays to characterize transcription has prev

56 diovascular benefit from fibrate even in the absence of atherogenic dyslipidemia.

57 e studied B cell development in the presence/absence of autoantigen by crossing the Ig KI mice to Tgm

58 The absence of B cells at the time of transplantation prolon

59 cell (ILC2) responses are exaggerated in the absence of basophils, resulting in increased inflammatio

60 Mechanistically, we found that in the absence of BD(L), the absolute cell number of CD4(+)Foxp

61 or inactivated intact Bp and the presence or absence of blocking antibodies or chemokines.

62 opsies, with gammac cytokines in presence or absence of BNZ-2.

63 The absence of bone in modern jawless fishes and the absence

64 n dynamics depend largely on the presence or absence of C(60).

65 In the absence of c-di-GMP, ShkA predominantly adopts a compact

66 conformational dynamics in the presence and absence of Ca(2+) Only AtSCS-A has the features of a cal

67 ngeable Ca(2+) regardless of the presence or absence of CaCO(3), whereas the second mechanism likely

68 plant that grows photoautotrophically in the absence of carotenes: a tobacco plant containing only th

69 In the absence of caspase-8, another of its paralogs, caspase-1

70 Importantly, despite the absence of catalytic activity, PTPRU binds substrates of

71 , control of lymphoma remained intact in the absence of CD4 T cells.

72 elicit an impaired antitumor response in the absence of cDC1s.

73 e further suggest that VDAC can occur in the absence of changes in early visual processing in cortex.

74 ore prominent as AMR can be diagnosed in the absence of circulating DSA.

75 erium and body composition); however, in the absence of clear microbiome-driven effects, caution is n

76 Maintenance of remission was defined as absence of clinical and histologic relapse and no premat

77 d abnormal echocardiographic measures in the absence of clinical HF was assessed.

78 restrain B cell responses to antigen in the absence of co-stimulation and do so, in part, by repress

79 s the judicious use of blood cultures in the absence of compelling evidence for bacterial coinfection

80 alleged destabilization of complex I in the absence of complex III.

81 However, lack of suitable methodology, absence of consensus sequon of O-GalNAcylation sites and

82 In the absence of contemporary, population-based epidemiologica

83 In the absence of controlled trials, treatment of neonatal seiz

84 Absence of corticospinal neurons also limited presymptom

85 Absence of cross-reactivity with mammalian species teste

86 In addition, we exploit the absence of cross-talk with respect to the majority of we

87 fficient secretory trafficking of ATZ in the absence of CRT is coincident with enhanced accumulation

88 We argue that the near-absence of Cryogenian tidal processes may have been one

89 (CSF1R), but some macrophages persist in the absence of CSF1R.

90 by NMR spectroscopy both in the presence and absence of Cu at a common interface.

91 stin recruitment can drive locomotion in the absence of D2R-mediated G protein signaling.

92 We show that in the absence of Dcc, some ganglion cell axons stalled at the

93 Normal aging, in the absence of dementia, also results in gradual cognitive d

94 pheral neuropathy (PN) is common even in the absence of diabetes.

95 ital bits are represented by the presence or absence of distinct DNA strands, called molecular bits (

96 In the absence of Dna2, 5'-flaps are thought to accumulate on t

97 xpanded similarly in mice in the presence or absence of docetaxel.

98 In the absence of drugs approved by regulatory agencies, the cu

99 In the absence of DXO1 function, transcripts displaying a high

100 In the absence of E-cadherin-mediated cell adhesion, LC numbers

101 trunk was significantly associated with the absence of ECs (29.6% in patients without ECs versus 16.

102 s a ratio of the binding of substrate in the absence of effector to the binding of the substrate in t

103 .48-3.03), with stronger associations in the absence of eLAP (HR = 2.87; 95% CI: 1.83-4.49) than with

104 Patients with PH in the absence of eLAP are at high risk of death and in need of

105 Given the absence of empirically supported treatment guidelines, a

106 lacked Tomes' processes, consistent with the absence of enamel rods, and underwent progressive cell p

107 nce of bone in modern jawless fishes and the absence of endochondral ossification in early fossil gna

108 ent to accelerate tumorigenesis, even in the absence of endogenous PD-L1; (3) PD-L1(+) T cells engage

109 We conclude that in the absence of epidemiological data, our catalogue of 3207 i

110 Impaired Treg suppression in the absence of ERbeta was associated with aberrant overexpre

111 1 before the onset of meiosis and found that absence of EWSR1 causes meiotic arrest with decreased hi

112 In the absence of EXO1, forks accumulate at stabilized G-quadru

113 notably by the presence of epilepsy and the absence of exocrine pancreatic insufficiency and hypopla

114 rlying epithelial cancerization field in the absence of exogenous carcinogens or promoters requires a

115 induced efficient wheat regeneration in the absence of exogenous cytokinins, which facilitates selec

116 Given the rapid presentation rate and absence of explicit instruction to categorise images, th

117 ESCs exhibit intrinsic heterogeneity in the absence of external gradients by forming interconverting

118 The absence of FDA oversight of serologic tests is concernin

119 er with Activin maintain self-renewal in the absence of fibroblast growth factor (FGF) signalling.

120 sirable for mechanophores to be inert in the absence of force but highly reactive under applied tensi

121 Absence of formal primary care diagnoses was a limitatio

122 Furthermore, in the absence of four SPA genes, the pivotal transcription fac

123 l specimen, radiological type), and presence/absence of free margins.

124 Even in the absence of fully established risk prediction schemes and

125 or male germlines causes sterility due to an absence of functional sperm, as depleted animals produce

126 otential limitation of the BFPP assay is the absence of fungal targets and Stenotrophomonas maltophil

127 They can promote viral replication in the absence of FXR-HVD interactions albeit less efficiently.

128 tion/function, and mRNA export occurs in the absence of Fzo1, which is required for mitochondrial dyn

129 response to lactobacilli in the presence and absence of Gardnerella vaginalis was measured using Lumi

130 y to lower circulating glucose levels in the absence of GDF15 activity.

131 selective TKI pressure, which occurs in the absence of genetic mutations.

132 In physiological studies, absence of GI neuron activity after AMPK suppression in

133 In total, 247 (93%) definitions required the absence of GLT, and 232 (87%) definitions specified nume

134 ivate programmed cell death pathways, in the absence of glucose.

135 eous in terms of size, charge, conformation, absence of glycosylation, and containing proper disulfid

136 nding with little clinical importance in the absence of gout or kidney stones.

137 us results in nuclear mTORC1 activity in the absence of growth factor stimulation.

138 , pursuit classification is far worse in the absence of head movement information.

139 ilippine tarsier (TsFpn) in the presence and absence of hepcidin solved by cryo-electron microscopy.

140 Key inclusion criteria were the absence of high-risk multiple myeloma and an Eastern Coo

141 ts showed that viremia rebounded despite the absence of HIV-1 adaptation to VRC01 and an average VRC0

142 in maintaining sequence conservation in the absence of homologous recombination.

143 show that sunk cost effects can arise in the absence of human-unique factors and may emerge, in part,

144 intake during lunch and in an eating in the absence of hunger task.

145 llular glutamine levels are decreased in the absence of HUWE1 and may contribute to MYC degradation.

146 coronavirus 2 infected patients, even in the absence of hypoxia.

147 stem and persistent BDG antigenaemia, in the absence of IFD, can result in deleterious pro-inflammato

148 n airway epithelial cultures, we observe the absence of IFN-I stimulation by SARS-CoV-2 alone but det

149 support that early changes occurring in the absence of IL-10 may lead to better bacterial control la

150 t eosinophil influx in immune control in the absence of IL-4/IL-13-dependent immune mechanisms.

151 sponses to the desired target region, in the absence of immune interference by other epitopes.

152 he majority of LVS remained cytosolic in the absence of immune pressure, eventually resulting in macr

153 drugs (AADs) in patients in the presence or absence of impaired Pitx2 expression remain unclear.

154 ct preload unresponsiveness diagnosed by the absence of increase in velocity-time integral of the lef

155 us absence of TLR7, 9, and 13 but not by the absence of individual TLRs.

156 llergen-induced MC degranulation even in the absence of inflammatory environment.

157 h, pinprick, and thermal hyperalgesia in the absence of injury, without associated changes in motor f

158 gly, they are also actively repressed in the absence of injury.

159 while allowing facile exfoliation due to the absence of interfacial forces as a nonpolar liquid.

160 -assemble into chiral materials, despite the absence of intrinsic molecular chirality.

161 ed MSMDS-related congenital mydriasis to the absence of iris sphincter muscle.

162 ks and the evidence of relevant mass loss in absence of large density variations within the comet's b

163 Conversely, the absence of LDs results in hyperactivation of MLX target

164 In the absence of LGP2, MDA5-mediated activation of type I IFN

165 ional regulation is presented whereby in the absence of ligand the riboswitch is largely unfolded, la

166 capitulate photoredox-like reactivity in the absence of light across a wide range of substrates in th

167 s can render the receptor active even in the absence of light.

168 ed to very different conclusions: the global absence of local topological-associated domains (TADs) i

169 nt mutations in DHFR are advantageous in the absence of Lon, but advantageous mutations are largely s

170 (Rapgef3), was strongly up-regulated in the absence of LRRK2 and down-regulated in its presence.

171 In the absence of lysis, MAC may induce intracellular signaling

172 tive TGFbeta-1 did not bind fibrillin in the absence of MAGP-1.

173 onic infection appear little affected by the absence of major T(M) chemokines.

174 on relative to control, respectively, in the absence of mammalian readers of DNA methylation.

175 required for cell proliferation even in the absence of MAX.

176 Methylotrophs persisted for weeks in the absence of methane, making them a powerful marker for ac

177 tion of B cell antigen receptors even in the absence of microbiota.

178 ition from G(1) to S phase is blocked in the absence of Midkine-a, resulting in significantly reduced

179 TPase obgE that is synthetically sick in the absence of Mla; providing another link between cell enve

180 Increased intersister repair in absence of Mph1 triggers a shift among remaining interho

181 In the near absence of mTOR, CDK1 activates eIF4E-dependent translat

182 transgene expression can persist even in the absence of mutations disrupting the silencing pathway.

183 due to point mutations in the PLP1 gene, and absence of myelin by MRI.

184 1 in mice leads to global depigmentation and absence of myelin from peripheral nerves, resulting from

185 ], 4.8 [2.6-9.0], P < 0.01) when compared to absence of NASH and AF (reference).

186 ring nucleotide symmetry consistent with the absence of negative cooperativity.

187 duction, caused by over acidification in the absence of NHE6.

188 Lastly, the absence of NLGN1 decreased neuronal counts in the dentat

189 mbryonic lethality, indicating that complete absence of NMNAT1 activity is probably not compatible wi

190 udies showed neuritis still developed in the absence of NOD-PerIg CD8(+) T cells but required CD4(+)

191 unique tissue(1-4), but whether and how the absence of nutrient supply regulates chondrogenesis rema

192 In the absence of obstructive coronary artery disease, intravas

193 a range of clinical conditions, even in the absence of obvious incentive to underperform.

194 The absence of one single murine dermal cell type, the innat

195 racellular domain (ECD) conformations in the absence of orthosteric ligands, which has limited our un

196 gnal-to-noise ratio in both the presence and absence of oxygen.

197 The absence of PAP I led to improved aminoacylation of 5'-im

198 stribution of the primer set, confirming the absence of PCR-based biases.

199 In the absence of perforin, we show that GrB enzymatic activity

200 n mutants show normal branching, despite the absence of peristalsis.

201 ndent preblocking effects in the presence or absence of pharmacologic sigma(1) receptor blockade with

202 It has been shown previously that in the absence of phosphatase, CaMKII monomers integrate over C

203 The absence of PlexA1, neuronal activity, Bax and Bak, or ca

204 Moreover, in the absence of Pob3, the FACT Spt16 subunit controls the 3'

205 This pattern helps to explain the absence of population-level Allee effects in this specie

206 In the absence of population-wide restrictions, isolation of in

207 The absence of premeiotic 24-nt phasiRNAs in maize and rice

208 kground incidence of HIV in the trial in the absence of PrEP, possibly augmented by external data.

209 patients with end-stage liver disease in the absence of prior heart disease.

210 In the absence of proper guidelines and algorithms, available r

211 The absence of prophages in cultures of the dominant lineage

212 In the absence of protein contacts, oxoA:G forms a wobble confo

213 [Co(13)C(2)(CO)(24)](4-) in the presence and absence of protons reveals ET kinetics and diffusion beh

214 In the near absence of proximal geological records from south of the

215 The presence or absence of PSB then determines whether the two states ha

216 erved that the levels of gC are lower in the absence of pUL47.

217 ialty Coffee Association regarding the total absence of Quaker beans in a natural specialty coffee ba

218 ikelet frequencies allowed to probe the near-absence of quartz in commercial, 100% silica samples, en

219 This is due to the absence of radiological and chemical signatures in the s

220 Tuberculosis (TB) control is hindered by absence of rapid tests to identify Mycobacterium tubercu

221 ical sepsis patients, persistent AKI and the absence of renal recovery are associated with distinct e

222 g-term therapeutic protein expression in the absence of repeated administration of pharmacological ag

223 ision and sentinel node biopsy, which showed absence of residual melanoma.

224 rs from baseline, as well as first sustained absence of retinal fluid and intraretinal fluid as evalu

225 rate task by presenting these stimuli in the absence of reward contingency and probing their effects

226 In the absence of reward, there was either no change in stimulu

227 e structural constraints are relieved in the absence of RNA secondary structure.

228 Accordingly, the absence of RSPO1/Rspo1 in XX humans and mice leads to te

229 uring zebrafish heart regeneration, and that absence of runx1 results in increased myocardial surviva

230 In the absence of S533 phosphorylation, it was proposed that an

231 itochondrial respiration in the presence and absence of saturating solutions of CO (160 mum) and nitr

232 Even in the absence of sea-level rise, deltas are increasingly vulne

233 primary outcome measure was the presence or absence of secondary glaucoma.

234 g a reversal of P450-based resistance in the absence of selection.

235 brids to measure TE accumulation in the near absence of selection.

236 y to bring about long-term divergence in the absence of selection.

237 tate rapid phenotypic divergence even in the absence of selective processes.

238 mission comprised 12 or more months with (1) absence of significant symptoms by validated instrument,

239 ted from an affected child revealed complete absence of skeletal muscle (i.e., segmental amyoplasia).

240 Absence of Smarcad1 leads to changes in chromatin access

241 n-inducible degron systems demonstrated that absence of SMC5/6 leads to DNA replication stress at lat

242 PAG) neurons) elicited USV production in the absence of social cues.

243 ently, we propose two factors to confirm the absence of soft deodorized oils in EVOO: R1 (10 x free a

244 s of the day, overall we highlight a notable absence of spatiotemporal response by female elk to the

245 In humans, absence of SPPL2a leads to Mendelian susceptibility to m

246 In the absence of SPRY1, FGF9, and FGF20, another FGF ligand, F

247 The absence of starch co-precipitation during RNA extraction

248 In the absence of STAT1 signaling, however, depletion of CD8 T

249 symbiotic than aposymbiotic anemones in the absence of stress suggest that they are important for th

250 ing uncertainty of a potential effect in the absence of stronger direct evidence.

251 s study, a total of 71 eyes with "resolved" (absence of subretinal fluid) chronic CSC at baseline and

252 apabilities, and the prediction that, in the absence of subterranean connections, extreme genetic div

253 In the absence of systemic immunosuppression, diabetic recipien

254 sidual asynchronous release remaining in the absence of SYT1.

255 Owing to the absence of tactile sensory information, prosthetic users

256 ins lacking gigC have impaired growth in the absence of the amino acid cysteine and that gigC regulat

257 escue the heparin/protein interaction in the absence of the canonical binding element.

258 o genome stability and cell viability in the absence of the FA pathway.

259 o and testing the effect of the presence and absence of the germ line on somatic repair under benign

260 everal, e.g. in Lafora disease caused by the absence of the glycogen phosphatase laforin or its inter

261 tate, which provides a counterbalance to the absence of the hydrophobic effect.

262 The incidence of LNM was 51/882 (6%) in absence of the independent risk factors.

263 ivation, Atg7 was deleted in the presence or absence of the master regulator of antioxidant defense n

264 liver, fails to promote liver injury in the absence of the microbiome in vivo.

265 The absence of the polybasic cleavage site in SARS-CoV-2 did

266 ain (USD) that promotes UTX stability in the absence of the rest of MLL3/4.

267 ion with distinct effectors, and presence or absence of the ring nuclease activity.

268 In the absence of the sulfone groups, we discovered that the te

269 either survival or cell death in presence or absence of their ligand, respectively.

270 rations of the thermal markers indicated the absence of thermal damage in the UHPH-treated musts, sin

271 Complete PVD was identified by the absence of these findings and considered a positive outc

272 Yet, sterile protection was achieved in the absence of this epitope, substantiating the concept that

273 dent, long-lived plasma cell population, yet absence of this kinase led to increased rates of Ig prod

274 can subtype, thus predicting the presence or absence of this virulence marker.

275 s could be recapitulated by the simultaneous absence of TLR7, 9, and 13 but not by the absence of ind

276 ts interesting electroanalytical properties, absence of treatment requirement, cost-effectiveness (c.

277 at ribosomes bypass tryptophan codons in the absence of tryptophan.

278 at result in anthocyanin accumulation in the absence of TT19.

279 Of note, necroptosis occurred only in the absence of TTP and was mediated by the expression of TNF

280 ton cells can form at high rates also in the absence of turbulence.

281 closporine A (CsA)-treated mice, even in the absence of UV light.

282 l approaches that could be considered in the absence of validated strategies.

283 In the absence of VHL, Th17 cells had decreased activation of S

284 gy source, spurred by rapid urbanization and absence of viable cleaner alternatives.

285 ed, PCR was performed on day four to confirm absence of virus replication.

286 d with electrogram fractionation even in the absence of voltage abnormalities.

287 Ectopically targeting E3 to membranes in the absence of WIPI2 is insufficient to support LC3 lipidati

288 aused strongly reduced rosette growth in the absence of wounding.

289 In the absence of WRN, the expanded TA-dinucleotide repeats are

290 ial structure and function that occur in the absence of, or in addition to, well-established cardiova

291 flux were measured from pH 5.0 to 9.0 in the absence or presence of a membrane potential (DeltaPsi, i

292 interaction of PT with VC1 and sRAGE in the absence or presence of calcium that acted as a competito

293 IA6-deficient bone marrow cells, both in the absence or presence of competition.

294 ection of a military facility to confirm the absence or presence of nuclear weapons and fissile mater

295 licited rapid formation of diformazan in the absence or presence of paraformaldehyde, (4) addition of

296 catalyzed oxidation reactions, in either the absence or presence of thiourea as a cocatalyst, was obt

297 The DID in illness-related school absences per 100 school days during the influenza season

298 e expression that take place in dystrophin's absence remain largely uncharacterized, as they are pote

299 tivity of tumor CD8(+) T cells, and in their absence, T cells did not lyse melanoma cells.

300 r lineages identified by pigment presence or absence (wild-type or knock-out lineages, respectively)