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1 for all pairs, indicating that it is not an absolute requirement.
2 NADH dehydrogenase I, although there was no absolute requirement.
3 structural proteins NifD and NifK will be an absolute requirement.
4 ed activation but indicate that it is not an absolute requirement.
5 show that NMDA receptor activation is not an absolute requirement and that DDI can be evoked solely b
6 rt/delta xprt mutant strain that exhibits an absolute requirement for 2'-deoxycoformycin, an inhibito
9 e phosphatases, except that there was not an absolute requirement for a conserved acidic residue that
13 ral T and dA bases in a reaction that has an absolute requirement for a divalent metal ion, physiolog
16 stead of a charged residue), but there is an absolute requirement for a Glu residue at position 6.
17 Ca(2+) release and therefore do not have an absolute requirement for a gradient in either inositol t
18 agnosis and treatment, such as the perceived absolute requirement for a ketogenic diet, the assumed l
19 time- and concentration-dependent, it had an absolute requirement for a peroxide substrate, and it wa
21 Substrate analogue inhibitors display an absolute requirement for a positive charge at the positi
22 al translation elongation is striking in its absolute requirement for a third factor, the ATPase eEF3
24 misfolding events occur that do not have an absolute requirement for abnormal Cys185-Cys187 disulfid
27 roup in the flexible side chain of PTX is an absolute requirement for activity, but its precise role
30 cannot grow on 6-oxypurines and displays an absolute requirement for adenine or adenosine and 2'-deo
33 of principle that TARP association is not an absolute requirement for AMPAR clustering at synapses, m
34 Thus, while aromatic residues are not an absolute requirement for amyloid formation by IAPP, they
35 ail (Vt) and residues 1-258 (D1), we find an absolute requirement for an interface involving the D4 d
37 Although most O(2)-dependent enzymes have an absolute requirement for an O(2)-activating cofactor, se
38 assay measuring loss of infectivity, is the absolute requirement for antibody-mediated protection in
40 recently been demonstrated that there is no absolute requirement for any AMPAR subunit for the recep
41 ectable, suggesting such asymmetry is not an absolute requirement for any of the functions of the cor
42 asmic pentameric motifs of Glut1 revealed no absolute requirement for arginine side chains at any of
44 ibrary [XXX(pT)XXX] against FHA1 revealed an absolute requirement for Asp at the +3 position and a pr
48 t would not be obvious otherwise, such as an absolute requirement for beta4GalT1 during convergent ex
51 servation that the C-13 side chain is not an absolute requirement for biological activity in a taxane
52 ative decarboxylation of d-malate and has an absolute requirement for both a divalent and monovalent
53 rate strong Ag-specific immunity that has an absolute requirement for both CD8(+) and CD4(+) T cells.
56 trabismus are unable to signal, revealing an absolute requirement for both proteins in cell-cell comm
57 illin, we demonstrate for the first time the absolute requirement for c-Src in villin-induced regulat
58 urin specifically in thymocytes, we found an absolute requirement for calcineurin in positive selecti
60 ular protection after preconditioning has an absolute requirement for CD14-expressing myeloid cells a
61 umor protection is Ag independent; 2) had an absolute requirement for CD4(+) and NK1.1(+) cells; 3) C
64 Activation of the ERK signaling pathway, an absolute requirement for cell proliferation, results in
65 constituted in vitro at 23 degrees C with an absolute requirement for chaperonins GroEL/GroES and Mg-
67 g membrane permeability but that there is an absolute requirement for cholesterol to mediate this eff
68 sister chromatid separation and revealed an absolute requirement for cohesin in hematopoietic stem c
73 cPLA2) has been disrupted to demonstrate the absolute requirement for cPLA2 in both the immediate and
74 reveal that agonistic anti-CD40 mAbs have an absolute requirement for cross-linking by inhibitory Fcg
75 th activities are zinc-dependent and show an absolute requirement for cysteine residues 1123, 1125 an
85 Phosphodiesterase activity of MJ0936 had an absolute requirement for divalent metal ions with Ni(2+)
88 This inhibition of translocation displays an absolute requirement for EF-1alpha; however, the depende
89 r binding determinant, a 3' U tail is not an absolute requirement for efficient RBP16-RNA binding.
90 eIF4E S209 phosphorylation, indicating their absolute requirement for eIF4E S209 phosphorylation.
91 ition of ASIC currents by syntaxin 1A had an absolute requirement for either gamma- or delta-hENaC.
92 ical pathway for antigen processing, with an absolute requirement for endosomal/lysosomal acidificati
94 eficient allograft recipients, indicating an absolute requirement for expression of these genes in CD
97 sential for antiviral activity but is not an absolute requirement for Gag binding, (ii) the trifluoro
99 embryos using reporter transgenes reveals an absolute requirement for Gata3 in controlling Fgf10 expr
101 AT3 signaling in autoimmunity relates to its absolute requirement for generating T(H)17 T cell respon
102 hoenolpyruvate (PEP) from oxaloacetate is an absolute requirement for gluconeogenesis from mitochondr
109 ated NO production and call attention to the absolute requirement for heterotrimeric G-protein betaga
110 cally targeting eukaryotic cells through the absolute requirement for high concentrations of choleste
111 lay a necessary role in CAV, as shown by the absolute requirement for histoincompatibility between do
113 Gs), providing the first demonstration of an absolute requirement for HSPGs in integrin-mediated cell
116 bitory Fcgamma-receptor (FcgammaR) IIB is an absolute requirement for in vivo antitumor activity of a
117 dies, and released exosomes; 2) a common and absolute requirement for inflammasome assembly and activ
119 lthough this extended base pairing is not an absolute requirement for initiation, it may convey added
123 rved hydrophobic patch on the AIPs and is an absolute requirement for interactions in self-activation
124 the possibility that genetic diversity is an absolute requirement for intraspecific chemical communic
127 urther, since dipeptidyl peptidase IV has an absolute requirement for l-Pro, a more metabolically-sta
128 mice, suggesting that eosinophils are not an absolute requirement for larval killing or development o
134 glutamate from the extracellular space is an absolute requirement for maintaining information process
138 he pore-forming mechanism of PFO exhibits an absolute requirement for membrane cholesterol, but the c
141 tile, we investigated for the first time the absolute requirement for motility in the mouse-tick life
143 hereas CD44s-fibrin(ogen) interaction has an absolute requirement for N-, but not O-, linked glycans.
144 se mEFs to prolonged hypoxia demonstrated an absolute requirement for N-terminal sites for HIF-1 alph
149 lusively on cytoplasmic proteasomes, with an absolute requirement for nuclear export of p53 via the C
150 on cytoplasmic proteasomes and hence has an absolute requirement for nuclear export of p53 via the C
152 ressed whether oligomerisation of TatC is an absolute requirement for operation of the Tat pathway by
153 ically relevant chemotherapeutic agents, the absolute requirement for p53 in this induction, and thei
155 ) rhythms in the hippocampus, demonstrate an absolute requirement for phasic inhibitory synaptic tran
156 It was also observed that while SHP-1 has an absolute requirement for phosphorylation at both motifs
157 d like a bona fide Kir channel displaying an absolute requirement for PIP(2) and Mg(2+)-dependent inw
158 Thus, our data indicate that there is an absolute requirement for PKCdelta in PMA-induced C4-2 ap
159 n the maintenance of mesangial cells and its absolute requirement for prevention of glomerular diseas
163 tment with caspase inhibitors, indicating an absolute requirement for programmed cell death and apopt
164 he presence of abundant antigen, CCR7 was an absolute requirement for protective immunity to T. gondi
168 immunodeficiency virus type 1 (HIV-1) has an absolute requirement for ribosomal frameshifting during
173 oli-cell only phenotype, consistent with the absolute requirement for Sin3A in germ cells' developmen
176 wed that at least one of the reasons for the absolute requirement for spermidine for growth is the sp
178 directly depend on Erk activation but has an absolute requirement for Src/Erk-mediated TXA2 generatio
179 on about dietary lipid requirements, and the absolute requirement for sterol is of particular note.
181 orming growth factor beta3 (Tgf-beta3) is an absolute requirement for successful palatal fusion, both
187 stimulating effects, apparently there is no absolute requirement for that molecule for the nuclear s
188 occurs in mammalian cells with regard to its absolute requirement for the action of Insigs, sensitivi
190 te for the first time, to our knowledge, the absolute requirement for the activity of MASP-1 protein
191 ggest that the expression of ClC-3 is not an absolute requirement for the activity of volume-sensitiv
192 ing mAb, we demonstrate that IFN-gamma is an absolute requirement for the antitumor effect of CD137 m
193 substitution on the nitrogen atom is not an absolute requirement for the antitumor effect of the ind
195 es that some agonistic antibodies display an absolute requirement for the C-terminal tail for FADD bi
196 rowth substrate, indicating that there is an absolute requirement for the C1 oxidation/reduction path
197 Our data suggest that dimerization is not an absolute requirement for the catalytic activity of the E
199 tumor activities of these antibodies have an absolute requirement for the coengagement of an inhibito
200 d suppression mechanism in which there is an absolute requirement for the cognate antigen of both the
201 atory interactions involving CD28 are not an absolute requirement for the control of infection with M
203 ortantly, AbetaP formation appeared to be an absolute requirement for the effects of hypoxia, since t
204 s aeruginosa exoenzyme S (ExoS) possessed an absolute requirement for the eukaryotic protein factor a
205 iable, indicating that this factor is not an absolute requirement for the formation of an active hepa
206 rganized secondary lymphoid tissue is not an absolute requirement for the generation of immune respon
209 ophobic reside at the -2-position but not an absolute requirement for the hydroxyl side chain of thre
210 l integrity of the 5BSL3 cruciform is not an absolute requirement for the kissing-loop interaction, s
212 ignal-regulated kinase (ERK) signaling is an absolute requirement for the maintenance of murine pluri
213 re and demonstrate that cancer cells have an absolute requirement for the membrane-anchored metallopr
215 er, the location of MOR at lipid rafts is an absolute requirement for the observed adenylyl cyclase s
217 lete independence of store depletion, and an absolute requirement for the pool of STIM1 that constitu
219 alters the amount of secretion but is not an absolute requirement for the processing and secretion of
220 arrested at the globular stage, revealing an absolute requirement for the production via these steps
223 rather than at discrete origins and have an absolute requirement for the recombinase RadA, unlike st
224 tion of the enzyme-coenzyme complex shows an absolute requirement for the same monocations required i
226 ner nucleotide opposite the lesion is not an absolute requirement for the successful initiation of NE
227 gesting that, in these mice, there is not an absolute requirement for the T4SS to mediate persistence
231 age at the C-extein branch point, and (d) an absolute requirement for the WCT triplet Block F Cys.
232 c cleavage of factor B by factor D is not an absolute requirement for the zymogen to active enzyme co
234 vitro and in vivo indicate that part of the absolute requirement for these factors is derived from t
235 While some natural isolates show a nearly absolute requirement for these two regulators, in others
236 and Mxi-Spa functions are complicated by an absolute requirement for these virulence proteins in inv
238 bunit of class I PI3-kinases demonstrated an absolute requirement for this form of the enzyme in GLUT
243 rsion of aldose and ketose sugars and has an absolute requirement for two divalent cations at its act
246 have shown that while the V2 loop is not an absolute requirement for viral entry, the absence of thi
247 )-induced thrombocytopenia, demonstrating an absolute requirement for VWF in this model (Stx has been
248 teraction of VP5 with pre-22a resulted in an absolute requirement for wild-type VP5 for growth of the
250 we discovered an unexpectedly selective and absolute requirement for XBP1 in eosinophil differentiat
251 xes, was found to correlate with, and had an absolute requirement for, the induction and nuclear loca
252 lymerase holoenzyme (sigma54-holoenzyme) has absolute requirements for an activator protein and ATP h
253 nd disease progression is not universal, and absolute requirements for epitope spreading in progressi
255 c-Jun/AP-1 trans-activating activity are not absolute requirements for ras transformation or invasion
256 +) T cells and of the type I IFN system were absolute requirements for the antitumor effects to occur
259 ome segregation, which is exemplified by its absolute requirement in yeast for the anaphase segregati
260 the P(+1) cleavage site (Ser(518)) shows an absolute requirement of a Ser, Thr, or Cys residue for e
262 t1 and Akt2 isoforms in this pathway, and an absolute requirement of Akt protein kinases for regulati
263 mportance of the WWD signature motif and the absolute requirement of all three histidines for the ass
264 hese results are unique in demonstrating the absolute requirement of alpha4 for sperm fertility.
266 form of cell injury, but also demonstrate an absolute requirement of Bax for mitochondrial permeabili
268 pases are cleaved and activated by GzmB, the absolute requirement of caspase activation for GzmB-indu
269 t Arf6-GTP, such a circuit would fulfill the absolute requirement of cytohesins for activation by Arf
270 general not identified, consistent with the absolute requirement of cytosolic translation for develo
272 specific GRK5 gene deletion to determine the absolute requirement of endogenous GRK5 for cardiac hype
273 vitro and in vivo models, we demonstrated an absolute requirement of functional p53 in arsenic-mediat
274 n in PS1-deficient cells and demonstrate the absolute requirement of functional presenilins for Abeta
278 ork of specific interactions illustrates the absolute requirement of N-sulfate groups vicinal to the
279 7B2 as regards this enzyme appears to be the absolute requirement of PC2 for 7B2 in the generation of
281 d adenylate cyclase activation; there was an absolute requirement of PKA for PAF-induced Src phosphor
283 wild-type and mutant dvCcmE' demonstrate the absolute requirement of residue C127 for noncovalent hem
291 A-1 conformations by Fab, we demonstrate the absolute requirement of the open LFA-1 headpiece for adh
292 liminated apoB RNA editing, establishing the absolute requirement of these components of the core enz
294 receptor delta null macrophages verifies the absolute requirement of this transcription factor in med
295 sts prepared from c-Abl null mice showed the absolute requirement of this tyrosine kinase in maturati
299 f allopurinol hypersensitivity, it is not an absolute requirement, suggesting that other factors also
300 fect on ToxR activity, although it is not an absolute requirement when ToxR is dimerized by a heterol