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1 oscopy demonstrated that diffusive transport accelerates.
2 merases, for example, modulate cell shape by accelerating actin filament assembly locally and slowing
3 ologies, whereas overexpression of C/EBPbeta accelerates AD pathologies, which can be attenuated by a
5 ) mice, a model of T1D, diabetes development accelerates after deletion of the Toll-like receptor 4 (
6 ly in life is predicted to be maladaptive by accelerating ageing disproportionally, decreasing fitnes
10 tation of telemedicine has been dramatically accelerated and will serve as a backbone for the future
11 d connections is consistent with theories of accelerated and/or delayed maturation, but may also invo
14 nd the longitudinal growth of functional BAs accelerated around age 70; average levels of BA curves d
17 ent as acute vasospasm, acute thrombosis and accelerated atherosclerosis, of cancer therapies have ga
21 oportionate biodiversity, and are subject to accelerating biotic homogenization, where specialist end
22 on the underlying regulation by combining an accelerated birch flowering program with a recessive mut
24 ytes (BMAd) have recently been implicated in accelerating bone metastatic cancers, such as acute myel
25 ene for Alzheimer's disease(11-14), leads to accelerated breakdown of the BBB and degeneration of bra
26 therapy-induced small extracellular vesicles accelerate breast cancer metastasis, and targeted inhibi
30 esults demonstrate that tumor progression is accelerated by hyperoxemia, hyperglycemia and hypercarbi
32 m, 2) the rates of AMP and ADO formation are accelerated by restricting the diffusion of substrates a
37 successful example of a general strategy to accelerate catalyst development which still remains unde
43 e programmability of DNA-DNA interactions to accelerate chemical reactions under diluted conditions u
44 group compounds, usually acids or bases, can accelerate chemical reactions when used in substoichiome
45 m lipid-modified reactants shows promise for accelerating chemical reactions in a traceless manner.
46 antly decreased bacterial burden in the FRT, accelerated Chlamydia clearance, and reduced hydrosalpin
47 liary clearance), inhaled ETX001 was able to accelerate clearance both when CFTR function was reduced
48 ) or 17-epi-RvD1 at the peak of inflammation accelerates clearance of bacteria, blunts PMN accumulati
49 zed, decomposition of this vast C bank could accelerate climate warming; however, the likelihood of t
51 HCO3- transporters (e.g. Na-H exchangers) by accelerating CO(2) / HCO3- -mediated buffering of acid-b
54 lead iodide (MAPbI(3)) films, age them under accelerated conditions, and determine features governing
55 potential cardiac maladaptations, including accelerated coronary artery calcification, exercise-indu
56 e of bromide in drinking water significantly accelerated Cr(VI) release because of its catalytic effe
57 o detrimental effects such as embrittlement, accelerated creep, phase instability, and radiation-alte
60 in S-nitrosothiols, and (7) procedures that accelerate decomposition of S-nitrosothiols, markedly re
62 es must take into account processes that may accelerate degradation of the canisters, plug, and SNF i
63 tached to misfolded AAT are not required for accelerated degradation mediated by the unconventional s
64 the underlying mechanisms for a PRV-induced, accelerated degradation of KIF1A, a kinesin-3 motor prom
65 indicated that the ZSWIM8 Cullin-RING ligase accelerates degradation of numerous miRNAs in cells of m
66 Pumilio-mediated repression and find that it accelerates degradation of target mRNAs, mediated by thr
67 ket of portable and wearable electronics has accelerated development in the construction of multifunc
68 enic' GBA1 variants were associated with the accelerated development of dementia and a more aggressiv
74 ART 2.0) for mixture analysis and subsequent accelerated discovery and characterization of new natura
76 asia-mutated (ATM) deficiency in CD4 T cells accelerates DNA damage, telomere erosion, and cell apopt
77 ated schedule (months 0, 6, and 12) or on an accelerated dosing schedule (months 0, 2, and 6) and/or
80 ants showed that transgene-produced FVIII-SQ accelerated early factor Xa and thrombin formation, whic
82 docannabinoid system in which GABA signaling accelerates endocannabinoid degradation, and triggers a
83 e report the use of aqueous microdroplets to accelerate enzymatic reactions and, in particular, to im
84 toxic-free intracellular iron levels and by accelerating erythroid output as reflected by increased
87 in combination with wood in a controlled and accelerated fermentation process for mimicking barrel ag
90 and alcohol use are patient risk factors for accelerated fibrosis progression, yet few randomized con
91 tional screening have been valuable tools in accelerated first-principles screening for the discovery
92 ADP- and low-ADP-stimulated respiration that accelerating flux through beta-oxidation generates a cor
94 e door-to-needle times of 60 minutes or less accelerated from 0.20% (95% CI, -0.43% to 0.83%) per eac
95 growth theory is used to show that crystals accelerated from an initial growth rate of 10(-6)-10(-7)
99 rder analyses may be the best way forward to accelerate gene finding for depression, or psychiatric d
100 undances and inhibiting cell growth but also accelerating genetic diversification and rapid adaptatio
102 to human environmental modifications and is accelerating, having increased sevenfold over the past 7
107 nsifying hydrologic cycle, which will likely accelerate Hg cycling in tandem with changing inputs fro
109 atforms will prove to be transformational in accelerating ideas from bench to bedside, maximizing sci
110 factor (pegfilgrastim) is used clinically to accelerate immune reconstitution following chemotherapy
113 contrast, NS5806 suppressed the current and accelerated inactivation of the channels when cells were
117 d by this TTA has great potential to further accelerate innovations in various 3D culture application
120 S1), which encodes cationic trypsinogen, can accelerate its autoactivation and cause hereditary or sp
122 a strategy performed in Brazil to enable and accelerate KT in children <=15 kg based on the establish
123 A editing, whereas moderately diverged genes accelerated later and retained relatively higher RNA edi
124 lutter phenomena, including blood damage and accelerated leaflet deterioration, this study demonstrat
125 ed atherosclerotic lesion size, but diabetes accelerated lesion progression, exemplified by necrotic
126 sis in a mouse hindlimb ischemia model, with accelerated limb blood flow recovery compared to control
127 a, but the mechanistic pathways that lead to accelerated liver fibrosis have not been well defined.
132 lopments in genomics offer an opportunity to accelerate marker discovery and use gene-focussed approa
138 nformational ensemble, we performed Gaussian accelerated molecular dynamics simulations on eight BAK1
139 in a degeneration-causing mutant background accelerated motoneuron loss and disease progression to t
140 ns in Medicine image data of knee images for accelerated MR image reconstruction using machine learni
141 ation of WNT/beta-catenin signaling strongly accelerated MYC-driven carcinogenesis in the liver.
144 ometimes water, additions, driven in part by accelerated nitrification on the initially more-fertile
145 that negative structural outcomes including accelerated OA progression, subchondral insufficiency fr
146 t that all male-mediated maturation (whether accelerated, on-time, or delayed) may be governed by sim
148 nts but that MSCs alone do not significantly accelerate or contribute to recovery of the blood system
150 ience offers powerful and underused tools to accelerate our ability to identify barriers and facilita
151 genome-driven clinical trials can evolve to accelerate our understanding of cancer biology and impro
155 to Alzheimer's disease dementia (n = 40) had accelerated p-tau217 compared to other mild cognitive im
158 The Antarctic Ice Sheet is losing mass at an accelerating pace, and ice loss will likely continue ove
160 expression aggravates EC-Tau aggregation and accelerates pathological tau spread into the hippocampus
162 indings reinforce the vital importance of an accelerated peace process to restore well-being in Syria
171 tient-derived fibroblasts and muscles caused accelerated proliferation, altered expression of cell cy
172 Delta/Delta) BRF1(Tg)) prostate cancer model accelerated prostate carcinogenesis and shortened surviv
174 cific depletion of KIF1A mRNA but also to an accelerated proteasomal degradation of KIF1A proteins, l
176 ition syndromes in which cancers arise at an accelerated rate and in different organs - the equivalen
177 econd messenger cGMP in darkness; and (3) an accelerated rate of decay of the effector enzyme phospho
178 sis of grafted-from polymerization kinetics, accelerating reaction discovery, and optimization of pol
179 nverts reactants' to products' bonding, will accelerate reactions, control regioselectivity, induce s
180 ests that non-identical amyloid proteins may accelerate reciprocal amyloid aggregation in a prion-lik
185 versity time series reveal global losses and accelerated redistributions of species, but no net loss
189 response (iPAR) model, by assessing whether accelerating reproduction following early-life adversity
191 n generative models to meet its potential to accelerate resistance-overcoming drug combination discov
192 e-ICH trials dataset, Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage II
196 aptamer, and they open new possibilities for accelerating RT maturation and interfering with viral re
197 and transformation in cells and dramatically accelerates SCLC progression in an Rb1/Trp53-deleted mou
198 unburned lowlands (r = 0.78, p < 0.001), but accelerated shrub-cover losses in burned lowlands (r = -
199 rophy is a significant milestone, serving to accelerate similar progress in a spectrum of neurologica
204 encapsulated peel extract was studied under accelerated storage conditions, in terms of phenolic con
205 bstrate binding, but rather a consequence of accelerated substrate binding kinetics as shown by satur
208 the transportability of AI models which can accelerate the adaptation process of external AI models
209 assembly pathways through seeded growth can accelerate the assembly kinetics and increase the optima
210 n of functional resistance genes in wheat to accelerate the breeding and engineering of disease-resis
211 nd population structure analysis may help to accelerate the breeding programs of lily through utilizi
213 regulating OAT1 function that can be used to accelerate the clearance of drugs, metabolites, or toxin
214 other neuronal subclasses should ultimately accelerate the comprehensive classification and characte
217 uorescence spectroscopic toolkit will likely accelerate the development of dynamic structural biology
220 ovide researchers with unique materials that accelerate the development of new breeding cultivars and
221 emaining challenges are provided, which will accelerate the development of new carbon material concep
222 outbreak expands globally, which may help to accelerate the development of novel diagnostics, drugs a
224 This gene-based, PheWAS-guided approach can accelerate the discovery of clinically relevant disease
225 smal CRISPR screening has great potential to accelerate the discovery of phenotypic negative regulato
226 new tools powering the scientific method to accelerate the discovery, prediction, and control of inc
227 easing the number of intermediate states can accelerate the EMT process and that adding parallel path
228 to activated Galpha subunits in G-proteins, accelerate the GTP hydrolysis, and thereby rapidly dampe
229 This shows that all countries would need to accelerate the implementation of policies for renewable
230 s implemented at the synchrotron beamline to accelerate the interconnected tasks of phase mapping and
232 expressed by target cells has been found to accelerate the loss of an enterovirus (CVB3/28) infectio
233 but NAbs may have the additional capacity to accelerate the loss of virus-infected cells through Fc g
235 neutralizing antibody LY-CoV555 appeared to accelerate the natural decline in viral load over time,
238 lanning, which are expected to significantly accelerate the search for pharmacologically relevant mol
239 omote the formation of alpha-syn aggregates, accelerate the severe and progressive degeneration of pa
241 to use a new batch of precursors and further accelerate the synthetic path discovery of QD compositio
242 rials of SARS-CoV-2 vaccine candidates could accelerate the testing and potential rollout of efficaci
243 nel to develop animal models for COVID-19 to accelerate the testing of vaccines and therapeutic agent
245 n response, natural selection is expected to accelerate the timing and pace of reproduction in indivi
246 nomenclature and subphenotype the disease to accelerate the translational path to new treatments.
248 ealing assays also confirmed that M2 and M13 accelerate the wound recovery process of Caco-2 cells at
249 ng, genetic disruption of lysosomal function accelerated the accumulation of storage bodies in AF(+)
252 ittle Ice Age around 1450 ce could also have accelerated the cessation of grazing pressure, particula
254 oninvasive clinical diagnostic tests and has accelerated the evaluation of ccf-nDNA abundance as a di
256 lactoferrin and milk serum proteins together accelerated the loss of bacteriostatic activity upon hea
258 Breakthroughs in materials engineering have accelerated the progress of immunotherapy in preclinical
259 Administration of G-CSF during extinction accelerated the rate of extinction, and administration d
260 vector inducing constant expression of CD28 accelerated the rejection of allogeneic skin grafts in y
264 factors, respectively, is identified, which accelerates the discovery of a series of new oxide perov
266 dical and the activated heteroarene but also accelerates the electron transfer from the nitrogen radi
268 ing TLR9-driven inflammation exacerbates and accelerates the onset of fulminant sHLH, in which system
270 irst evidence that a radical SAM enzyme MoaA accelerates the radical-mediated C-C bond formation.
271 observed that cross-seeding by sRPT fibrils accelerates the rate of lRPT aggregation, resulting in p
272 ization cues but increases overall activity, accelerates the refinement of calcium signaling and exci
273 indings show that, whereas physical salience accelerates the speed of attentional selection, value-dr
274 al fluid (CSF) and chronic sleep deprivation accelerates the spread of tau protein aggregates in neur
275 ed membrane repair increases endocytosis and accelerates the uptake of gold nanoparticles into U373MG
276 gies and cross-disciplinary partnerships are accelerating the biological and clinical interpretation
278 cific phenotypes relevant to the brain while accelerating the maturation of neuronal networks, import
279 and eleclazine has unique effects, including accelerating the onset of slow inactivation and impairin
280 urity of nanomedicine for global healthcare, accelerating the pace of transformation of its great pot
281 ution tracking and profiling approaches have accelerated these efforts, revealing ILC2 transcriptiona
282 ress in this clonally propagated crop can be accelerated through the discovery of markers and candida
285 ify gaps, to provide a potential roadmap for accelerating translation of microbiome science toward mi
289 motes intratumoral genetic heterogeneity and accelerated tumor evolution(1-3); however, its frequency
292 nical PD-L1-PD-1 axis and were sufficient to accelerate tumorigenesis, even in the absence of endogen
294 have been incriminated as probable cause of accelerated vascular calcification (VC) in patients on h
295 ning, which causes beach loss globally, will accelerate with sea level rise (SLR), causing more beach
298 their constituent species; however, the risk accelerates with the magnitude of warming, threatening 1