ライフサイエンスコーパス: accelerating

1 ts, and the pace of progress in this area is accelerating.

2 Automated glycan assembly (AGA) aims at accelerating access to synthetic oligosaccharides to mee

3 merases, for example, modulate cell shape by accelerating actin filament assembly locally and slowing

4 erface rupture may be a primary mechanism of accelerating actin filament fragmentation by other actin

5 Affinity for C3b, cofactor and decay-accelerating activities, and serum assays demonstrate th

6 ute to the regulatory functions termed decay-accelerating activity (DAA) and cofactor activity (CFA).

7 the potentiating Ab and similarly, the decay-accelerating activity of all mutants is increased.

8 ly in life is predicted to be maladaptive by accelerating ageing disproportionally, decreasing fitnes

9 reproductive effort decreases somatic state, accelerating ageing, is central to our understanding of

10 apeutic applications, aspects that relate to accelerating aging are no less clinically significant.

11 An accelerating Airy-beam light-sheet critically enabled im

12 cells play a key role in transplantation by accelerating allograft rejection and preventing toleranc

13 micrograph and tomogram interpretability and accelerating analysis.

14 Between the accelerating and decelerating conditions, no differences

15 In light of the accelerating and rapidly evolving overdose crisis in the

16 state-of-the-art applications, considerably accelerating and standardizing production without sacrif

17 Environmental change is rapidly accelerating, and many species will need to adapt to sur

18 cessional grassland plant diversity leads to accelerating annual carbon storage rates that, by the se

19 olonged survival of tumor-bearing animals by accelerating apoptosis of leukemic cells.

20 ion in the US pharmaceutical market, such as accelerating approval of non-first-in-class drugs, will

21 ve sea-level rise enhances aggradation rates-accelerating avulsion frequency and associated hazards c

22 Here, we estimate impacts of ramping up and accelerating baloxavir treatment on population-level inc

23 ing quantum states in (224)Rn and (226)Rn by accelerating beams of these radioactive nuclei.

24 duction' may accumulate with each pregnancy, accelerating biological aging.

25 atility have led to its widespread adoption, accelerating biomedical research and discovery in human

26 n and remark on recent technologies that are accelerating biosensor development.

27 oportionate biodiversity, and are subject to accelerating biotic homogenization, where specialist end

28 a microfluidic device (PepS) automating and accelerating blood sample preparation for bottom-up MS-b

29 enditure, altering substrate metabolism, and accelerating body water and muscle protein loss.

30 ytes (BMAd) have recently been implicated in accelerating bone metastatic cancers, such as acute myel

31 rols, older individuals with AUD demonstrate accelerating brain tissue loss with advanced age.

32 eeding by increasing selection intensity and accelerating breeding cycles.

33 , these genomic resources will be useful for accelerating breeding of this underutilized grain crop a

34 the advancements in theoretical methods for accelerating catalyst design and discovery.

35 KN1A expression indirectly via EZH2, thereby accelerating cell-cycle transit.

36 -term imaging unleash its great potential in accelerating cell-free synthetic biology.

37 isms are unclear, increased oxidative stress accelerating cellular aging has been shown to play a rol

38 it does alter channel functional properties, accelerating channel opening at more hyperpolarized memb

39 decoupling the contradictory requirements of accelerating charging and discharging processes, we sele

40 m lipid-modified reactants shows promise for accelerating chemical reactions in a traceless manner.

41 lesterol-supersaturated gallbladder bile and accelerating cholesterol crystallization.

42 In the face of accelerating climate change, mitigating local stressors

43 ; trends which are expected to continue with accelerating climate change.

44 Accelerating clinical diagnosis from pathology images an

45 asing virus transmission and replication and accelerating clinical progression to AIDS.

46 hey also agreed that the best strategies for accelerating clinical translation of imaging inflammatio

47 HCO3- transporters (e.g. Na-H exchangers) by accelerating CO(2) / HCO3- -mediated buffering of acid-b

48 Accelerating coastal development is increasing the expos

49 Fusobacterium nucleatum is implicated in accelerating colorectal cancer (CRC) and is found within

50 We demonstrate that Bennu's rotation rate is accelerating continuously at 3.63 +/- 0.52 x 10(-6) degr

51 rnova explosion that could inflict damage by accelerating cosmic rays that can deliver ionizing radia

52 The Preclinical Working Group of Accelerating COVID-19 Therapeutic Interventions and Vacc

53 line the significance of the MT as a time of accelerating CVD risk, thereby emphasizing the importanc

54 acutely diminishes DAT surface expression by accelerating DAT internalization.

55 ere recorded during the task of anticipating accelerating, decelerating, or steady beats after direct

56 Ecosystem Services (IPBES) found widespread, accelerating declines in Earth's biodiversity and associ

57 innovations that would be most effective in accelerating declines in tuberculosis burden.

58 Accelerating declines of an increasing number of animal

59 women who delivered term singletons, with an accelerating decreasing trend observed across Stage 1 an

60 has antagonistic roles in tumorigenesis, by accelerating development of benign tumors while restrain

61 g precise, real-time digital quantification, accelerating development of critically needed diagnostic

62 , injection molding) can be used seamlessly, accelerating development.

63 ed traction as a significant tool capable of accelerating diagnosis, prognosis, and biomarker discove

64 nterpreting emerging immunotherapy data, and accelerating discovery within radioimmunotherapy interve

65 y associated with enhancing HIV replication, accelerating disease progression and diminishing host-im

66 teria trigger acute pulmonary exacerbations, accelerating disease progression and mortality rate.

67 r dichotomous role in protecting against, or accelerating, diseases of the cardiovascular system and

68 ription factors (TF) by reducing binding and accelerating dissociation, while a small group of TFs ha

69 gical information in images hold promise for accelerating drug discovery.

70 Forest mortality is accelerating due to climate change and the largest trees

71 ity index is an open-access, scalable system accelerating early-stage drug target selection for immun

72 In the face of accelerating ecological change to the world's oceans, se

73 tion advocate that the time for courageously accelerating efforts to ensure a world where no child di

74 into a single electrochemical device and for accelerating electrocatalytic reactions that consume pro

75 his paper, we investigate the possibility of accelerating electromagnetic simulations using the data

76 promotes ATP7B interaction with HSP70, thus accelerating endoplasmic reticulum (ER) degradation of t

77 hematopoietic recovery after irradiation by accelerating endothelial and LepR+ cell regeneration and

78 ibiotic prodrug is an effective strategy for accelerating enzymatic prodrug hydrolysis and enhancing

79 Rgs4 is a GTPase accelerating enzyme implicated in plasticity mechanisms

80 ows and should be amenable to automation for accelerating enzyme screening in industrial applications

81 toxic-free intracellular iron levels and by accelerating erythroid output as reflected by increased

82 tic code, affording a biocatalyst capable of accelerating ester hydrolysis with greater than 9,000-fo

83 ns, we detected a pattern of directional and accelerating evolution towards larger brains, consistent

84 As a rapidly accelerating expression of global change, plastics now o

85 n 158 assemblages, we detected significantly accelerating extinction and colonisation rates, with bot

86 nd CFA by constructing chimeras of the decay-accelerating factor (DAF) that exhibits DAA and membrane

87 n some patients to deficiency of CD55 [decay-accelerating factor (DAF)], but the mechanism underlying

88 Cell membrane-anchored Decay Accelerating Factor (DAF, a.k.a.

89 e, we show that podocyte expression of decay-accelerating factor (DAF/CD55), a complement C3 converta

90 IgM Ab but no other isotypes, whereas decay accelerating factor (Daf1)(-/-) mice elicited more robus

91 bionts, which we propose to be a significant accelerating factor in the transitions to an obligately

92 ntrinsic constraints in the amplitude of the accelerating fields sustainable by radio-frequency accel

93 uably the most promising, thanks to the high-accelerating fields they can sustain, greatly exceeding

94 rain and leads to partial interface rupture, accelerating filament fragmentation.

95 ause of their nonuniform elasticity, thereby accelerating filament severing.

96 ADP- and low-ADP-stimulated respiration that accelerating flux through beta-oxidation generates a cor

97 human-caused sixth mass extinction is likely accelerating for several reasons.

98 Globally accelerating frequency and extent of wildfire threatens

99 undances and inhibiting cell growth but also accelerating genetic diversification and rapid adaptatio

100 e effective breeding strategies conducive to accelerating genetic gain for this trait.

101 with genomic selection would be relevant for accelerating genetic gains for yield in winter wheat.

102 nomics, and a resource for trait dissection, accelerating genetic gains in future chickpea breeding.

103 tein that inhibits DNA repair by HR, thereby accelerating genome destabilization, micronucleus genera

104 es of species benefit or suffer in a time of accelerating global change.

105 Assuming no feedbacks, accelerating global sea-level rise will eventually surpa

106 asing transparency, democratizing access and accelerating global synthesis.

107 Due to the limit in accelerating gradients in conventional particle accelera

108 nding to activated G-protein alpha-subunits, accelerating GTP hydrolysis.

109 to human environmental modifications and is accelerating, having increased sevenfold over the past 7

110 the discovery of novel anti-infective agents accelerating healing of infected injured tissues is cruc

111 They play an essential role in accelerating high-energy electrons forming the hazardous

112 The global urbanization rate is accelerating; however, data limitations have far prevent

113 melting near the ice sheet grounding lines, accelerating ice flow, and controlling the pace of futur

114 atforms will prove to be transformational in accelerating ideas from bench to bedside, maximizing sci

115 ead of monosulcates and tricolpate eudicots, accelerating in the Albian.

116 Sea ice reduction is accelerating in the Barents and Kara Seas.

117 l when further division of labor produces an accelerating increase in absolute productivity (i.e. pro

118 on between rice accessions and potential for accelerating induction was analysed by gas exchange.

119 Accelerating induction would boost photosynthetic and re

120 oelectronically favorable cis-TS negates the accelerating influence of the properly aligned C-O and C

121 ial determinants of health; prioritizing and accelerating investments in biomedical research; and gro

122 ced several light-capturing responses, while accelerating it reduced phototropin's sensitivity for ch

123 ine-protein kinase-like (MASTL) is a mitosis-accelerating kinase with emerging roles in cancer progre

124 Rapidly accelerating knowledge and continued research promise to

125 models, making evidence-driven decisions and accelerating knowledge discovery in life sciences.

126 cooperatively in denser collagen matrices by accelerating leader-follower switching thus decreasing l

127 r assessing vaccine efficacy and potentially accelerating licensure.

128 heet is currently experiencing sustained and accelerating loss of ice.

129 nd the importance of genetic surveillance in accelerating malaria elimination efforts.

130 The spatial pattern of accelerating mass changes reflects the geography of NAO-

131 CTLs augment the chemotactic signal, further accelerating mass recruitment in a positive feedback loo

132 principles methods can be a valuable tool in accelerating materials discovery to develop improved cer

133 In highly mobile populations, accelerating MDA implementation increases likelihood of

134 ression quantitative trait loci database and accelerating medicines partnership type 2 diabetes melli

135 erglycemia-induced epigenetic modifications, accelerating mitochondrial damage and diabetic retinopat

136 litating reorganization of adsorbed protein, accelerating molecular recognition, and informing the fu

137 ds CS-ST, VN-S, and VN-ST performed well for accelerating monoexponential T(1rho) mapping, with MNAD

138 of Gompert'z hazard function was increased, accelerating mortality accrual at later ages.

139 uced colitis by decreasing oxidative stress, accelerating mucosal repair, and promoting the resolutio

140 S967 shortened Ca(2+) transient duration via accelerating Na(+)/Ca(2+) exchanger (I(NCX))-mediated Ca

141 e potential to anticipate care needs, either accelerating needed care or redirecting patients toward

142 integrates with the superoxide intermediate, accelerating O(2) reduction kinetics and reducing side r

143 ction of gravitational waves in spacetime by accelerating objects.

144 cleotide-binding N domain is responsible for accelerating OLF aggregation in vitro.

145 onmental risk factors can play a key role in accelerating or decelerating disease onset and progressi

146 the development of advanced hydrogels toward accelerating organoids and OOC research in biomedical ap

147 Both CA and TCN were effective in accelerating osteogenesis at the interface between bone

148 nical research and even clinical practice by accelerating our understanding of disease mechanisms on

149 Accelerating our understanding of the mind's structure r

150 However, given the accelerating pace of drug development, there is a crucia

151 The accelerating pace of genome sequencing throughout the tr

152 The Antarctic Ice Sheet is losing mass at an accelerating pace, and ice loss will likely continue ove

153 Single-cell data are being generated at an accelerating pace.

154 oevolutionary engines' within each fragment, accelerating pathogen diversification, and increasing pa

155 autoimmune diseases and allosensitization by accelerating pathogenic IgG antibody degradation.

156 High-latitude warming is capable of accelerating permafrost degradation and the decompositio

157 CPE treatment in limiting tissue injury and accelerating post-stroke recovery.

158 egy we narrowed down the optimization to two accelerating potentials, and we defined the optimization

159 Despite accelerating progress towards schistosomiasis control in

160 ter of computer simulations hold promise for accelerating progress, but developing a deeper understan

161 within ACNP, as well as recommendations for accelerating progress.

162 imaging, genetic, and molecular methods are accelerating progress.

163 Accelerating prostate DWI by reducing the number of acqu

164 terotrimeric G proteins through their GTPase-accelerating protein (GAP) activity, which is conferred

165 n and promoting relaxation due to its GTPase accelerating protein activity toward Galphaq.

166 We further found that phosphorylated sites accelerating protein turnover are functionally selected

167 ession of genes encoding Rho-specific GTPase-accelerating proteins (Rho-GAP), which negatively regula

168 to binding coagulation factors Xa and Va and accelerating prothrombin activation.

169 mics studies may be expected to appear at an accelerating rate in the near future given the early suc

170 The accelerating rate of ice loss reflects regional-specific

171 d Ice Sheet (GIS) has been losing mass at an accelerating rate over the recent decades.

172 xpression datasets are being generated at an accelerating rate, but can be complex to visualize.

173 mbitious conservation targets in response to accelerating rates of global biodiversity loss.

174 sis of grafted-from polymerization kinetics, accelerating reaction discovery, and optimization of pol

175 ergistically reducing energetic barriers and accelerating reaction kinetics for catalyzing the oxygen

176 nt offers a new approach to enhancing and/or accelerating recovery after SCI or in other disorders.

177 hanism as well as less electron-rich ligands accelerating reductive elimination as a nitronate-specif

178 te Shigella vaccine efficacy and potentially accelerating regulatory approval.

179 expression, the cost would increase, thereby accelerating removal of resistant strains.

180 response (iPAR) model, by assessing whether accelerating reproduction following early-life adversity

181 We propose accelerating reservoir washout during ART by triggering

182 improve function of hHsp90alpha in yeast by accelerating return to the open state.

183 Our distribution data also suggest an accelerating role of climate change in the range expansi

184 male and female mice, better balance on the accelerating rotarod in females, and improved motor coor

185 Accelerating rotarod performance also distinguished phen

186 of Nrp2 impairs sensorimotor learning on the accelerating rotarod without affecting goal-directed ins

187 ocomotion and impaired motor learning on the accelerating rotarod.

188 These findings suggest that with higher and accelerating RSLR today, enhanced climate variability co

189 aptamer, and they open new possibilities for accelerating RT maturation and interfering with viral re

190 te change is intensifying tropical cyclones, accelerating sea-level rise, and increasing coastal floo

191 cally beginning slowly with a prespike foot, accelerating sharply to initiate a spike, reaching a pea

192 plant uptake of nutrients and water, thereby accelerating SOC turnover through both stabilization and

193 switches in migratory behavior, potentially accelerating speciation.

194 GeNN is a C++-based meta-compiler for accelerating spiking neural network simulations using co

195 ural damage or may itself be risk factor for accelerating spread of degenerative pathology.

196 is crucial in understanding, controlling and accelerating spreading processes for diseases, informati

197 ert calcium silicate-based materials thereby accelerating stem cell activation and repair.

198 parameters and the dynamic evolution of the accelerating structure.

199 n free-space lasers directly incident on the accelerating structures, limiting the scalability and in

200 a still underutilized but powerful tool for accelerating such evaluations.

201 y can enable customized peptide therapies by accelerating synthesis and increasing purity.

202 dating the underlying biology is crucial for accelerating technological progress, as the biofluid its

203 In recent years, the accelerating tempo of epizootic and zoonotic disease eve

204 orldwide; through strategic partnerships for accelerating test development, in particular with vaccin

205 designed system by microfluidic systems for accelerating the analysis time.

206 y-terminated background ligand is capable of accelerating the back-isomerization reaction by more tha

207 al the key role of electrostatic steering in accelerating the binding between flow-activated VWF and

208 mine remediation and waste stabilization by accelerating the biogeochemical cycling of iron.

209 gies and cross-disciplinary partnerships are accelerating the biological and clinical interpretation

210 ther the electron donor or acceptor, thereby accelerating the charge transfer.

211 kill cancer cells harboring herpesviruses by accelerating the completion of the lytic cascade.

212 ese enzymes modulate microtubule dynamics by accelerating the conversion of microtubules from their s

213 eding induces nucleation at low temperatures accelerating the crystallization process.

214 results demonstrate the potential of SR for accelerating the data-driven design and discovery of new

215 These results open the possibility of accelerating the debittering of natural olives by preser

216 king of RSV-specific CD4+ cells, potentially accelerating the development of effective vaccines.TRIAL

217 Our work will facilitate accelerating the development of graph-based approaches i

218 re them with current state-of-the-art tools, accelerating the development of new, more accurate AF so

219 logical underpinnings of mental diseases and accelerating the development of novel medication strateg

220 led important advances in cancer research by accelerating the development of study models or as a too

221 -HBV) is a coalition of experts dedicated to accelerating the discovery of a cure for chronic hepatit

222 w powerful de novo transcriptomics can be at accelerating the discovery of new peptide families.

223 ion of wider natural product chemical space, accelerating the discovery of selective lead compounds.

224 Human perturbation of natural systems is accelerating the emergence of infectious diseases, manda

225 located in the active center responsible for accelerating the enzyme-catalyzed reaction.

226 biophysical and biochemical techniques, are accelerating the field.

227 a reactant in the carbonylation process, and accelerating the final reductive elimination event.

228 e findings highlight the importance of Mn in accelerating the formation of PbO(2) in water with Pb(II

229 ed and unstructured data holds potential for accelerating the generation of impactful biological insi

230 that substrate stimulates ATP hydrolysis by accelerating the IF-to-OF transition.

231 US Department of Energy (DOE) is focused on accelerating the introduction of affordable, scalable, a

232 ition to producing MV/m quasi-static fields, accelerating the ions and confining the majority of the

233 This indicates that accelerating the LRT2-catalyzed isomerization would not

234 cific phenotypes relevant to the brain while accelerating the maturation of neuronal networks, import

235 and eleclazine has unique effects, including accelerating the onset of slow inactivation and impairin

236 It is responsible for accelerating the oxidative dissolution of sulfide minera

237 tion and analysis of multiple CO landscapes, accelerating the pace at which mechanisms for the regula

238 ibe an emerging regulatory framework that is accelerating the pace of clinical trials in children as

239 r cycle, FucoID should have the potential of accelerating the pace of personalized cancer treatment.

240 urity of nanomedicine for global healthcare, accelerating the pace of transformation of its great pot

241 Warmer temperatures are accelerating the phenology of organisms around the world

242 ovascular morbidity and mortality partly via accelerating the process of cellular aging.

243 ion of biosensors with different devices for accelerating the process of defeating the pandemic is pr

244 ls and is activated during amyloid toxicity, accelerating the processing of SINE RNAs and gene hyper-

245 d sequencing and scaffolding technologies is accelerating the production of reference-quality assembl

246 Phylogenomic research is accelerating the publication of landmark studies that ai

247 recovery times for nerve-injury patients, by accelerating the rate at which damaged nerves reconnect

248 oxidative damage to essential biomolecules, accelerating the rate of ageing.

249 SCU2 M140I variant can substitute for FXN in accelerating the rate of iron-sulfur cluster formation o

250 The role of residual water toward accelerating the rate of reaction is established through

251 atically alters their electronic properties, accelerating the rates of both redox-based MOF conductiv

252 Recently, accelerating the redox kinetics using catalytic material

253 is essential for effective cross-coupling by accelerating the reduction of Ni(II) to Ni(0) and counte

254 safe and effective therapeutic strategy for accelerating the rehabilitation of patients admitted to

255 Pharmacologically enhancing mitophagy and accelerating the removal of damaged mitochondria are of

256 Antarctic, this symbiosis has a key role in accelerating the replacement of formerly dominant moss c

257 ockade of the inflammatory cascade and/or by accelerating the resolution of inflammation.

258 cted the biodegradation of beta-TCP and BBM, accelerating the resorption of these materials.

259 rdination of Cu(II) plays a critical role in accelerating the reversible dissociation of dimethylglyo

260 FoxO/DAF-16 also prevents food scarcity from accelerating the selection against selfish mtDNA.

261 enantioselectivity enhancements result from accelerating the transformation of the major enantiomer

262 ework, context and ultimately guidelines for accelerating the translation of machine-learning-based i

263 e around the furcal lesion, thus potentially accelerating the treatment decision-making process.

264 o use, customizable, and extensible, thereby accelerating the use of simulations to understand the mo

265 This provides added incentives for accelerating the vaccine production cycle to reduce the

266 inorganic materials is a grand challenge for accelerating their discovery using computations.

267 classical and alternative C3 convertases by accelerating their spontaneous decay.

268 ase the functionality and biomimicry of ACs, accelerating their translation and application in biotec

269 glycoclusters to substrates was efficient at accelerating these reactions.

270 Understory fires represent an accelerating threat to Amazonian tropical forests and ca

271 ntaining or enhancing facial bone thickness, accelerating tooth movement, expanding the scope of safe

272 penditure on infrastructure construction, by accelerating trade and transportation, is likely to prom

273 ovement using genomic tools is essential for accelerating trait genetic gains.

274 navigate these nodal axonal constrictions by accelerating transiently, much as the current increases

275 ify gaps, to provide a potential roadmap for accelerating translation of microbiome science toward mi

276 um, and the potassium cation plays a role in accelerating transmetalation.

277 s-end tracking, whereas TOG2 is critical for accelerating tubulin polymerization.

278 rs CD8(+) T cell function in the murine TME, accelerating tumor growth.

279 with mutation of DDX3X or loss of GSE1 both accelerating tumorigenesis.

280 rted to reach the age of 65 in 2011, rapidly accelerating U.S. population aging.

281 VCP/p97 increases BMP signaling by accelerating ubiquitin ligase Smurf1 degradation.

282 This resource will contribute to accelerating understanding of the physiological relevanc

283 ion of these important synaptic proteins are accelerating understanding of their actions.

284 distributions of both species in response to accelerating urbanization, connectivity and climate chan

285 However, we argue that such studies, by accelerating vaccine evaluation, could reduce the global

286 rticles impact the biogeochemical cycles via accelerating various reaction rates and enabling biologi

287 that worsen, limit or reverse a potentially accelerating ventilator-induced lung injury process.

288 aled a novel mechanism of cytosolic Na(+) in accelerating vesicle endocytosis.

289 Alternatively, upon mapping the reaction accelerating vibrations an image of the RC can be recons

290 ge of the RC is crucial to pick the reaction accelerating vibrations.

291 n and emergence of parasites and diseases to accelerating warming globally but empirical studies demo

292 ensity analysis quantified the proportion of accelerating wave energy (perfusion efficiency).

293 rcise response was defined as an increase in accelerating wave energy from rest to peak exercise.

294 lysis was used to quantify the proportion of accelerating wave energy; a normal exercise response was

295 g production of a key inflammatory cytokine, accelerating weight regain, and limiting behavioral defi

296 Disruption of Arctic ecosystems is accelerating, with impacts ranging from mixing of biotic

297 Accumulation of plastic litter is accelerating worldwide.

298 erapeutic potential of miR-10b and miR-21 in accelerating wound closure was demonstrated in in vitro

299 were capable of reducing bacterial load and accelerating wound healing in an excisional wound model.

300 onic medicines, for treating disease states, accelerating wound healing processes and eliminating inf