ライフサイエンスコーパス: accessory molecule

1 ecognition complex, rather than simply as an accessory molecule.

2 pecifically associates with vimentin without accessory molecules.

3 sence of costimulatory interactions from APC accessory molecules.

4 eractions between T cell coreceptors and APC accessory molecules.

5 eliminate the BCR's dependence on additional accessory molecules.

6 r (TCR) with peptide-MHC complex and through accessory molecules.

7 hat evade recognition by other activating or accessory molecules.

8 3-zeta, independent of costimulation through accessory molecules.

9 fect was not due to TLR-induced induction of accessory molecules.

10 ll-like receptors (TLR) and their associated accessory molecules.

11 endoplasmic reticulum (ER) involves several accessory molecules.

12 pressing MHC class II molecules with defined accessory molecules.

13 plus costimulatory signals delivered through accessory molecules.

14 nt with appropriate contacts of cell surface accessory molecules.

15 hesion molecule and activation receptor DNAX accessory molecule 1 (DNAM-1) correlates with the quanti

16 DNAX accessory molecule 1 (DNAM-1) is a costimulatory and adh

17 DNAX accessory molecule 1 (DNAM-1) is expressed on all CD8(+)

18 DNAX accessory molecule 1 (DNAM-1), an adhesion molecule belo

19 a ligand for the activating NK receptor DNAX accessory molecule 1 (DNAM-1).

20 eptors (NCR), NK group 2 D (NKG2D), and DNAX accessory molecule 1 (DNAM-1).

21 and CD16, whereas expression of DNAM-1 (DNAX accessory molecule 1), CD28, PD-1, TIGIT, and CD94 varie

22 icity, which could be inhibited by anti-DNAX accessory molecule 1, anti-NKG2 family member D, and ant

23 l expression of the activating receptor DNAX accessory molecule 1.

24 poliovirus receptor are engaged by both DNAX accessory molecule-1 (CD226) and Tactile (CD96).

25 DNAX accessory molecule-1 (DNAM-1) is a signal-transducing ad

26 Engagement of NKG2D and DNAX accessory molecule-1 (DNAM-1) receptors on lymphocytes p

27 adhesion molecules, the immunoreceptors DNAX accessory molecule-1 (DNAM-1), CD96 molecule (CD96), and

28 we describe a novel accessory molecule, DNAX accessory molecule-1 (DNAM-1), that is constitutively ex

29 DNAX accessory molecule-1 (DNAM-1, also known as CD226) is an

30 gh natural cytotoxicity receptor (NCR), DNAX accessory molecule-1 (DNAM-1; CD226), perforin, and gran

31 , Fc epsilon receptor I-gamma (FCER1G), DNAX accessory molecule-1 (DNAM1/CD226), granzymes, tumor nec

32 fected monocytes, whereas expression of DNAX accessory molecule-1 and 2B4 was not.

33 s-infected monocytes, but Abs to NKp30, DNAX accessory molecule-1, and 2B4 had no effect.

34 er, activating receptors such as NKp46, DNAX accessory molecule-1, and NKG2C and stimulatory receptor

35 of some activating NK receptors (e.g., DNAX accessory molecule-1, NKp46, and NKG2D) and decreased IF

36 y selective dephosphorylation of CD19, a BCR accessory molecule and coreceptor.

37 Caveolin-2 is an accessory molecule and the binding partner of caveolin-1

38 f major histocompatibility complex (MHC) and accessory molecules and induction of the costimulatory m

39 ing advances in understanding how proteases, accessory molecules and intracellular pathways influence

40 n inflammatory milieu consisting of enhanced accessory molecules and proinflammatory cytokines in the

41 e their maturation by upregulating important accessory molecules and secreting cytokines, all of whic

42 We compared the expression of necessary accessory molecules and the functional antigen-presentin

43 ese receptors are propagated and modified by accessory molecules, and discuss how signal amplificatio

44 re tested for expression of HLA-DR and other accessory molecules, and function in hematopoietic colon

45 1 or its LPS undergo maturation, up-regulate accessory molecules, and release proinflammatory (IL-1be

46 nfluenced by cytokines, concentration of Ag, accessory molecules, and the affinity of the MHC-TCR int

47 chanisms are involved in recruiting the TCR, accessory molecules, and the integrin LFA-1 to the conta

48 subset and down-regulation of CD28 and LFA-1 accessory molecules are associated with an increased ris

49 ell surface markers, adhesion molecules, and accessory molecules are targets of biological therapy, b

50 enes, such as invariant chain (Ii) and H2-DM accessory molecules, are controlled by the master transc

51 Recent studies have suggested that the accessory molecules B7.1 (CD80) and B7.2 (CD86) differ i

52 gle HLA-peptide complex along with the human accessory molecules B7.1, ICAM-1, and LFA-3.

53 xamined their expression of MHC class II and accessory molecules before and after maturation in cultu

54 GF-RI and TGF-RII, and at the mRNA level for accessory molecules beta-glycan and endoglin.

55 of the covalent peptide/class II complex and accessory molecules by the same adenovirus provides a un

56 ow imbalanced signaling derived from TCR and accessory molecules can contribute to autoimmune disease

57 t of B cells, have been shown to function as accessory molecules capable of modulating T cell activat

58 ripts of the signaling adapter MyD88 and the accessory molecule CD14 were also detected in all tissue

59 CR) itself, its coreceptors CD4 and CD8, the accessory molecule CD2, and the costimulatory receptors

60 imulatory receptors CD28 and CTLA-4, and the accessory molecule CD2.

61 lipid phosphatases (CD45, SHP-1, SHIP), and accessory molecules (CD21/CD19, CD22, FcR gamma 2b).

62 of normal T cells in vitro by binding to the accessory molecule CD26, a dipeptidase expressed on the

63 The accessory molecule CD28 delivers a costimulus that acts

64 artially dependent on ligation of the T cell accessory molecule CD28.

65 ecule shown to interact with and bind to the accessory molecule CD4, retain their significant disease

66 Instead, the T cell accessory molecules CD4 and CD28 cooperated to induce au

67 se C-gamma, and greater activation of the Ig accessory molecule CD79b in response to treatment with a

68 TCR ligation with little or no accessory molecule coreceptor engagement induced efficie

69 Two accessory molecules denoted GDNF family receptor 1 and 2

70 -cell antigen receptors or a number of other accessory molecules did not account for the functional d

71 he periphery, these interactions, refined by accessory molecules, direct the expansion, differentiati

72 It engages the activating receptor DNAX accessory molecule (DNAM)-1, the inhibitory receptor TIG

73 +) T-cell evasion caused by an impaired DNAX accessory molecule (DNAM)-1/CD155 interaction.

74 Here, we describe a novel accessory molecule, DNAX accessory molecule-1 (DNAM-1),

75 , spontaneously up-regulate MHC class II and accessory molecules during overnight culture, and stimul

76 ified TCR alpha beta pairs in the absence of accessory molecules, ensuring isolation of high-affinity

77 gand-dependent DC activation with regards to accessory molecule expression as well as nitric oxide an

78 depending on altered peptide ligand dose and accessory molecule expression by APC.

79 The effect on accessory molecule expression of microglial cells cultur

80 nonspecific inflammatory stimuli up-regulate accessory molecule expression on resting APC before an e

81 overnight culture they continued to increase accessory molecule expression.

82 CD22 is a key accessory molecule for Ag receptor signaling in B cells

83 ty complex (MHC) antigens, and costimulatory/accessory molecules for T-cell activation.

84 target cells, demonstrating a physiological accessory molecule function for CD161.

85 integrated and reveals a novel component of accessory molecule function.

86 ch the cysteine protease cathepsin S and the accessory molecule H-2DM play an essential role.

87 The class II-like accessory molecule H2-DM functions as a conformational e

88 atibility complex (MHC) II-/-, class II-like accessory molecule (H2-DMalpha)-/- using MHC I-/- and wi

89 y directed against a variety of cell surface accessory molecules has been effectively utilized to pro

90 termined by the balance between provision of accessory molecule help and the affinity of peptide/MHC

91 Accessory molecule help enhanced the expression of CD25,

92 ells have enhanced responsiveness to Ag when accessory molecule help is limiting and consequently can

93 In the absence of accessory molecule help, early and late phase activation

94 L-2, were found to be extremely dependent on accessory molecule help, with little or no expression ev

95 Consistent with the expression of these accessory molecules, IFN-gamma-treated SJL/J astrocytes

96 ator of peripheral T cell activation, and an accessory molecule in positive selection.

97 The integrin LFA-1 serves as an accessory molecule in T cell activation.

98 ngerhans cells is thought to be an important accessory molecule in the allergy-specific T cell activa

99 n impede fibril clearance; thus, they may be accessory molecules in AD.

100 include T-cell subsets, adhesion molecules, accessory molecules in antigen presentation, novel infla

101 To define the role of individual accessory molecules in cytokine production during primar

102 ever, most information regarding the role of accessory molecules in immune responses has been derived

103 ane transporters and up-regulation of immune accessory molecules in intestinal epithelial cells.

104 applicable to investigate the roles of other accessory molecules in the engagement of the TCR class I

105 II molecule by substituting B7-1 with other accessory molecules in the recombinant adenovirus.

106 We investigated how the accessory molecule interactions encountered during T cel

107 Among these accessory molecules, interactions between CD28/CTLA-4 wi

108 ce indicated that coexpression of the MHC II accessory molecule invariant chain (Ii) inhibited presen

109 However, coexpression of the MHC class II accessory molecule invariant chain (Ii), or deletion of

110 ed to endocytic compartments by the class II accessory molecule invariant chain (Ii), which itself mu

111 C II vaccine cells do not express the MHC II accessory molecules invariant chain and DM, they are lik

112 tched allogeneic vaccines do not express the accessory molecule, Invariant chain, they present MHC II

113 ut also up-regulates the class II-associated accessory molecules, invariant chain (Ii) and DM.

114 HC class II (class II) is facilitated by the accessory molecules, invariant chain (Ii) and H2-M.

115 One of these accessory molecules is tapasin, a transmembrane protein

116 Furthermore, blockade of CD40 or CD40L accessory molecules largely neutralized the EV augmentat

117 xpression of B7.1 or B7.2 without additional accessory molecules led to very high production of inter

118 nus and thereby recruits Syntaxin6 and other accessory molecules like VAMP2, Rab6, and Rab8 on Salmon

119 e alveolar macrophages in the absence of the accessory molecule LPS binding protein (LBP).

120 histocompatibility complex class II (MHC II) accessory molecule mainly expressed in the thymic medull

121 Accessory molecules (major histocompatibility complex cl

122 inducible protein-10 and RANTES), the immune accessory molecules, MHC class II, B7.2, ICAM-1 and VCAM

123 urrent stimulation of the TCR complex and an accessory molecule, most frequently CD28.

124 surface expression of MHC class II or other accessory molecules necessary for Ag presentation.

125 It is well known that interactions between accessory molecules on T cells and their ligands on APC

126 nterleukin-1, interleukin-12, B lymphocytes, accessory molecules on T lymphocytes, and angiogenic fac

127 t simply by disrupting TCR interactions with accessory molecules on the hybridoma.

128 This not only induces expression of immune accessory molecules on the infected cell, but also allow

129 e regulated by lineage/ activation-dependent accessory molecules on the target.

130 results indicate that VCAM-1 can serve as an accessory molecule or potential coreceptor for HTLV-1-in

131 Signaling through accessory molecules or costimulatory molecules is a crit

132 suggesting that M-tropic viruses utilize an accessory molecule other than fusin.

133 olled by the level of expression of multiple accessory molecule pairs integrated with the number and

134 fferentiation is mediated by a switch in the accessory molecule recruited by Fc gamma RI, which lacks

135 (IFN-gamma) on microglial expression of the accessory molecules required for antigen presentation we

136 In general, agonist Abs to accessory molecules shifted the response curves for IFN-

137 ent system that includes the CD3 complex and accessory molecules such as CD4 and CD8.

138 y bridging TAP to MHC class I and recruiting accessory molecules such as ERp57 and calreticulin.

139 extracellular space and involve a variety of accessory molecules, such as glycosaminoglycans, one of

140 Accessory molecules, such as HLA-DM and invariant chain,

141 CD19 functions as a B cell antigen receptor accessory molecule that modifies antigen receptor signal

142 ine (Ramos) to express high levels of immune accessory molecules that are commonly found on blood B c

143 ecent studies have now identified unexpected accessory molecules that are critical to CD1 assembly an

144 0-bearing APCs to express immune stimulatory accessory molecules that facilitate immune recognition.

145 of TF is not involved in the recruitment of accessory molecules that influence adhesive functions.

146 cognition by down-regulation of cell surface accessory molecules that participate in the formation of

147 the major capsid protein (hexon) and several accessory molecules that stabilize the capsid.

148 a G-protein-coupled receptor's acting as an accessory molecule to present ligand to another receptor

149 HeLa cells, suggested that CD44 might be an accessory molecule to Pvr, the cell receptor for poliovi

150 o enhance CAR-T cells with the expression of accessory molecules to address these challenges.

151 ms allowing recognition by costimulatory and accessory molecules to be weak and yet specific are very

152 lent peptide/class II complex may direct the accessory molecules to exert their function specifically

153 ed by mK3 if they were recruited by these ER accessory molecules to the proper position relative to t

154 to class II molecules, thereby bringing CD4 accessory molecules to the surface of class II-bearing s

155 n kinases, actin-binding proteins, and other accessory molecules to the T cell/APC synapse.

156 demonstrated the existence in T. pallidum of accessory molecules typically associated with sensory tr

157 e infiltration, the CNS expression of immune accessory molecules was induced or up-regulated, includi

158 ss II molecules with defined combinations of accessory molecules were used to present peptide antigen

159 autonomous antigen-induced production of an accessory molecule with constitutive CAR expression in a

160 that mediate retention and to interfere with accessory molecules within the arterial wall that promot