ライフサイエンスコーパス: accomplish

1 ail beyond what laboratory experiments could accomplish.

2 , which makes high-quality care difficult to accomplish.

3 to perform a function that one alone cannot accomplish.

4 ation cascade of amino-1,2,5-oxadiazoles was accomplished.

5 tated emergent catalytic transformations are accomplished.

6 tituent to unprotected amines has never been accomplished.

7 the P(1)-guided emergence of [3 x 3] CDNs is accomplished.

8 substituted tetrahydrofuran ring system, was accomplished.

9 HCV NS3/4a protease inhibitor BI 201420 was accomplished.

10 s reported that such multicolor AGNPs can be accomplished.

11 w-resolution structures, suggest how this is accomplished.

12 stituted 1,2,3-triazoles (1,4-cDTs) has been accomplished.

13 pproaches to ent-oxycodone were designed and accomplished.

14 ugh base pairing has been conceptualized and accomplished.

15 How is memory search accomplished?

16 2, spermatogenesis arrests due to failure to accomplish a metabolic shift during meiosis.

17 'Parallel' proliferation pathways accomplish a similar drug resistance outcome.

18 ich may nonlinearly shape how a social group accomplishes a collective task.

19 Me-DuPHOS as catalysts has been successfully accomplished, achieving very high levels of stereoselect

20 flexible diagnostic strategies are needed to accomplish and sustain the goals of comprehensive pre-pr

21 The human sense of smell can accomplish astonishing feats, yet there remains a prevai

22 This manipulation could be accomplished at room temperature; hence this opens avenu

23 n of the substituted tryptophan moieties was accomplished at the very end of the synthesis and thus a

24 n-3-yl)pyrimidine-2,4(1H,3H)-diones has been accomplished based on a one-pot multicomponent reaction

25 al localisation task, we show that the brain accomplishes Bayesian causal inference by dynamically en

26 h, referred to hereafter as the CofActor, we accomplished both light- and energetic/oxidative stress-

27 nt deformation and asymmetric wall fracture, accomplishing both high stiffness and high energy absorp

28 chnology with potential to meet this need by accomplishing broad-based, rapid nucleic acid sequence i

29 ining data from the two modalities, which we accomplish by using the heme signals from MALDI-MSI and

30 The process is accomplished by [(Me(3)P)(4)NiH]N(SO(2)CF(3))(2) in the

31 d in vivo The encoding of cigarette smoke is accomplished by a broad receptor response pattern, and 1

32 This procedure can be accomplished by a competent graduate student or technici

33 This is accomplished by a novel procedure for universal retentio

34 al synthesis of 3-lipid I and 3-lipid II was accomplished by a novel route involving an efficient sol

35 This was accomplished by a retrospective analysis with data from

36 pected, we observed that catalysis is mostly accomplished by a small set of residues performing a lim

37 It cannot be accomplished by affected individuals alone.

38 erochromatin at the nuclear periphery can be accomplished by attaching a small subset of loci, even i

39 Photorelease of alcohols is often accomplished by attachment with carbonate linkages, whic

40 Tuning of the reaction kinetics is accomplished by balancing inhibitor and initiator conten

41 This can be accomplished by bulk sample analysis with liquid chromat

42 usion, ANGPTL4-mediated inactivation of LPL, accomplished by catalyzing the unfolding of LPL, does no

43 The eSimoa assay is accomplished by conjugating substrates to paramagnetic b

44 imilar reversal of disease phenotype is also accomplished by converting astrocytes to neurons using a

45 De novo establishment of DNA methylation is accomplished by DNMT3A and DNMT3B.

46 Global epigenomic profiling was accomplished by employing an Assay for Transposase-Acces

47 This was accomplished by enhancement of van der Waals (vdW) force

48 The selection of spectral data was accomplished by extreme gradient boosting (XGBoost), an

49 This solution is accomplished by formation of a hydrophobic solid-electro

50 on of electrical impulses, a function mainly accomplished by gap junctions (GJ) composed of Cx43 (con

51 Functional characterization was accomplished by gene overexpression while haplotype anal

52 y to catalyze Henry reactions that cannot be accomplished by homogeneous analogs, and discrimination

53 e show that maternal immune activation (MIA) accomplished by infection with a mouse-adapted influenza

54 The functional validation of EGR 1 gene was accomplished by knocking out (KO) of EGR 1 in cultured l

55 This is accomplished by maintaining a permanent barrier through

56 Treating such wounds might be accomplished by managing OS levels with antioxidants com

57 gate in a mixture of 12 components was thus accomplished by monitoring formation of the click produc

58 This is accomplished by monitoring the spontaneous, time-depende

59 f pyridylphenol derivatives was successfully accomplished by our unique method.

60 ace area by an order of magnitude and can be accomplished by physically mixing a precatalyst (Pd/TiO(

61 ange of thermal and mechanical properties is accomplished by polymerising a variety of commercially a

62 CO(2) detection is accomplished by quantifying the capacitance modulations

63 This is accomplished by reconstitution of PTEN-null embryoid bod

64 Implementing these methods is often accomplished by researchers with domain expertise but wi

65 hypothesized that such modifications can be accomplished by small molecules that bring a kinase in p

66 ls (PGCs), we show that cluster dispersal is accomplished by stabilizing and orienting migratory forc

67 e propose a model whereby T4P unipolarity is accomplished by stimulation of T4P formation at the lead

68 This is accomplished by the activation of inflammatory caspases,

69 This was accomplished by the addition of the water-miscible organ

70 The synthesis of 1H-triazoles can be accomplished by the Banert cascade from propargylic azid

71 This process was likely accomplished by the binding of Mt2 ectodomain to Hjv and

72 ins is initiated by ubiquitination, which is accomplished by the coordination of multiple E3 ubiquiti

73 This is best accomplished by the FE crack band model which, when coup

74 xon guidance and dendritic morphogenesis are accomplished by the same extracellular ligand in vivo.

75 This is accomplished by the use of di- or trisubstituted alkenes

76 14-membered macrolide core of migrastatin is accomplished by the use of furyl carbinol in 13 linear s

77 olphins can exceed speeds of 50 km/h, a feat accomplished by thrusting the flukes while adjusting att

78 ve analysis of diffusion-weighted images was accomplished by two independent readers; images were ass

79 Identification of specific genotypes can be accomplished by visual recognition of their distinct phe

80 iron-catalyzed hydroarylation of allenes was accomplished by weak phenone assistance.

81 ' positions, a task that has previously been accomplished by X-ray crystallography.

82 Most bacteria accomplish cell division with the help of a dynamic prot

83 er of cobblestone-like epithelial cells that accomplishes critical functions for the retina.

84 They accomplish depth perception, despite their tiny brains,

85 work, a fast chiroptical sensing method that accomplishes determination of the enantiomeric excess an

86 downstream partners, individual projections accomplish distinct functions: hypothalamic and extended

87 rious polyquinane-based natural products was accomplished efficiently by employing ring-rearrangement

88 Coronary revascularization is accomplished either by percutaneous coronary interventio

89 iator chiral tetrahydroisoquinoline has been accomplished employing diastereoselective Pictet-Spengle

90 e annulation of indolines with aziridines is accomplished employing the combination of DDQ and NaOCl

91 can be an effective and advantageous way to accomplish extension and outreach objectives in plant pa

92 Administration of a high dose of GAd accomplished extensive transgene expression in the lung

93 e carboxylic acid as an appropriate means to accomplish favorable pharmacokinetic properties by reduc

94 e[CO(2) ] treatment was accomplished for 97.7% of the scheduled operation time,

95 glet oxygen-mediated green protocol has been accomplished for the first time for the photochemical tr

96 anine and beta-selenoleucine amino acids was accomplished from Garner's aldehyde as a common starting

97 -mucorisocoumarins A (5) and B (6) have been accomplished from the common intermediate (-)-6-O-methyl

98 tely links with the cardiovascular system to accomplish gas exchange.

99 and then forms a complex with apo-sGCbeta to accomplish heme delivery to sGCbeta.

100 This is accomplished here with mass-selective axial ejection (MS

101 fer and copper-promoted radical cyanation-to accomplish highly enantioselective hydrocyanation withou

102 n polarization with droplet microfluidics to accomplish in-droplet demixing.

103 ntagonist and three of its stereoisomers was accomplished in 10 steps.

104 paniculata (known as "King of Bitters"), was accomplished in 14 steps (LLS).

105 embly and testing of the optoPlate-96 can be accomplished in 3-4 h, at a cost of ~$600.

106 y of the initial scale-up challenges and was accomplished in 46% overall yield from 3,3-dimethyldicyc

107 dPCR-based SMA copy number determination was accomplished in 90 min with a walk-away workflow identic

108 ns of budding yeast Kinesin-14 Cik1-Kar3 are accomplished in a complex with Bim1 (yeast EB1).

109 rough whole-genome library generation can be accomplished in as little as 1 week, although 2-3 weeks

110 cyclic monoterpene indole alkaloid, has been accomplished in both racemic and enantioselective manner

111 ation of TET expression by ascorbic acid was accomplished in cultured human keratinocyte stem cells t

112 markers, this has not yet been successfully accomplished in human hair follicles (HuHF).

113 th liquid ketones and cyclic ethers has been accomplished in minutes using t-butyl hydroperoxide in t

114 expression without transgene integration is accomplished in Nicotiana benthamiana (Nb), Eruca sativa

115 levels with a sensitivity down to 0.5 fg are accomplished in notably small natural water samples.

116 at "establishing trust and comfort" was best accomplished in person, and the vast majority felt it wa

117 This feat is accomplished in the absence of an external energy source

118 tricarbonyl(tropone)iron and allylamine was accomplished in three steps: (1) aza-Michael addition of

119 of mouse ESCs via CRISPR-Cas9, which can be accomplished in ~4-8 weeks.

120 nge in behavior after learning in Aplysia is accomplished, in part, by regulating connections between

121 Mechanisms by which this is accomplished include AR amplification and expression of

122 e and analysis of stressed samples were also accomplished, indicating this method can be utilized to

123 This is accomplished instead via the establishment of disease to

124 How this is accomplished is controversial.

125 cell immunosurveillance, though how this is accomplished is not always well defined.

126 How this is accomplished is not entirely clear.

127 How membrane bending is accomplished is not yet fully understood but has been li

128 rted in each cell cycle(2-5) but how this is accomplished is poorly understood.

129 regation, but how mammalian crossing over is accomplished is poorly understood.

130 ties of equilibrium binding, yet how this is accomplished is unknown.

131 We propose IsoFun to accomplish Isoform Function prediction based on bi-rando

132 driven motor proteins are nature's choice to accomplish it.

133 ugh transgenesis in the zebra finch has been accomplished, it is with a very low efficiency of germ-l

134 Here we determine how Wnt3 accomplishes long-range distribution in the zebrafish br

135 tures are one of the potential candidates to accomplish low-temperature and solution-based device ass

136 Compensation of hyperphoria by VFV is accomplished mainly by IR muscle relaxation in the hypot

137 They are utilized in nature to accomplish many cellular tasks.

138 matography, on a CSH Phenyl-Hexyl column, to accomplish mixed-mode anion-exchange separations, which

139 hot approach for link discovery which can be accomplished much more rapidly.

140 ormations, including a designed cascade that accomplishes nine distinct chemical reactions in one-pot

141 Much still needs to be accomplished, not only to refine but also to build suppo

142 HiBiT luminescent peptide tag can easily be accomplished on a large-scale and whether integrated rep

143 We developed the VIS-OCT-FAF technology to accomplish optical coherence tomography (OCT) and FAF si

144 ave implemented national climate policies to accomplish pledged Nationally Determined Contributions a

145 How salamanders accomplish progenitor cell proliferation while faithfull

146 tion of possible secondary structures can be accomplished quickly despite the NP-complete nature of t

147 elial barrier function, although how this is accomplished remains elusive.

148 lum (ER) to cause infection, yet how this is accomplished remains enigmatic.

149 izing microtubule plus ends, but how this is accomplished remains unclear.

150 uire a physical presence in a lab and can be accomplished remotely.

151 e the potency of chemoselective reactions to accomplish sequence-controlled heterolayered dendrimers.

152 This review highlights the work accomplished since 2018 which focuses on using Raman spe

153 mpelomin B and epi-ampelomin B, D, and E was accomplished starting from toluene, through a chemoenzym

154 Results: Radiolabeling was accomplished successfully with an incorporation radioche

155 show how modern software development can be accomplished successfully, irrespective of subject area.

156 e hippocampus and dorsolateral striatum, may accomplish such a goal.

157 cal means of localized immunomodulation that accomplishes sustained graft survival in the absence of

158 for genetically modified macrophages, which accomplished targeted gene delivery, and significant exp

159 y rely on such hierarchical presentations to accomplish tasks big and small-from planning one's day,

160 integration of materials with mechanisms to accomplish tasks-such as generating motion or lifting an

161 To accomplish that, a two-dimensional hydraulic model (iRIC

162 Sandwich ELISA and its variants accomplish the capture and detection of a target protein

163 of both substrates (sugar and nucleotide) to accomplish the conformational change leading to a closed

164 internal and external validation criteria to accomplish the guidelines defined by the Organization fo

165 Cells undergo autophagy to accomplish the lysosomal digestion of intracellular mate

166 To accomplish the objectives of this study, we selected to

167 nucleophilicity of the phosphanido moiety to accomplish the P-C bond formation, the key role of the h

168 ved to generate the nucleophile necessary to accomplish the reaction.

169 Thus, two mechanisms have evolved to accomplish the reisomerization: one involving the well-s

170 To accomplish the remarkable task of lifelong infection, th

171 lved a system of guide RNA categorization to accomplish the same two-pathway lifestyle.

172 e as a regio- and stereochemical template to accomplish the selective oxyamination of both activated

173 recycling electrochemical cell allowed us to accomplish the simultaneous desorption of high-purity CO

174 ds in an acidic environment was exploited to accomplish the synthesis of alkenes using a one-pot, two

175 , and the successful outcome was utilized to accomplish the total synthesis of an aminopropyl linker-

176 The approach allows us to accomplish the tricyclic core structure efficiently from

177 Recently, aNHCs successfully accomplished the metal-free catalytic formylation of ami

178 Divergent scaling still accomplishes the essential homeostatic task of modifying

179 ectodomain, the reptilian orthoreovirus p14, accomplishes the same task by hijacking the actin cytosk

180 ate oxidation is a promising alternative for accomplishing the decoloration of raw sugar solutions.

181 ociation between GO terms and isoforms, thus accomplishing the prediction of GO annotations of isofor

182 ndergo a plethora of conformational changes, accomplishing their biological functions.

183 To accomplish these repair activities, APE1 must recognize

184 To accomplish these roles, mitochondria rely on the genetic

185 s and a relay sensing strategy that together accomplish these tasks with five classes of compounds in

186 unolabeled Nuclei Sequencing), a method that accomplishes these goals.

187 weakly C-H acidic substrates; however, they accomplish this at pH 7 using only collections of noncov

188 We accomplish this by combining DESI-MSI with immunofluores

189 We accomplish this by incorporating various 3D printed comp

190 demonstrate an approach, which allows one to accomplish this challenging task.

191 We accomplish this feat by combining different stimulus fea

192 These microorganisms are able to accomplish this feat by enhancing the activity of the CO

193 They accomplish this feat by means of elastic compliance of c

194 of H3 acetylation, but how SIRT6 is able to accomplish this feat is unknown.

195 One paradigmatic process to accomplish this goal efficiently is the transition-metal

196 To accomplish this goal, three organic waste streams were u

197 ed in the water and on the seafloor can help accomplish this goal.

198 Attempts to accomplish this have followed two major paths: deletion

199 rk that health care organizations can use to accomplish this task across diverse settings.

200 p learning method, which we call Locator, to accomplish this task faster and more accurately than exi

201 To accomplish this task, calibration sets have large sample

202 tion of a ribosome is to build ribosomes; to accomplish this task, ribosomes make ribosomal proteins,

203 To accomplish this task, we designed zinc finger proteins (

204 To accomplish this task, we have considered the clinical an

205 n relies on the use of the Henry reaction to accomplish this task.

206 However, generalizable strategies that accomplish this with high specificity have been slow to

207 One way to accomplish this would be to identify which advances in k

208 To accomplish this, all plants depend on proteins called ex

209 Several tests have been proposed to accomplish this, but these either rely on false assumpti

210 To accomplish this, GPCRs first bind to an intermediary sig

211 To accomplish this, it is often necessary to employ complex

212 To accomplish this, PubMed and PsycINFO were searched for p

213 To accomplish this, rather than directly simulating folding

214 To accomplish this, two serum samples from 20 kidney transp

215 To accomplish this, we analyzed EEG signals from two differ

216 To accomplish this, we applied a targeted sequencing of 37

217 To accomplish this, we developed a discovery pipeline using

218 To accomplish this, we developed an infrared pump, vibratio

219 To accomplish this, we engineered an electrical-electrochem

220 To accomplish this, we first tested three inducible mural c

221 tein subunit vaccines against C. burnetii To accomplish this, we formulated C. burnetii Ags with a no

222 To accomplish this, we have designed monomers with a nonpla

223 To accomplish this, we prime-boosted rhesus macaques with c

224 To accomplish this, we recruited individuals (n = 11, n = 8

225 To accomplish this, we synthesized fluorescent sp(3)-defect

226 To accomplish this, zeros are usually added to each sequenc

227 rtment, but available ART does not currently accomplish this.

228 ttle is known, however, about how our brains accomplish this.

229 ision support (CDS) systems could be used to accomplish this.

230 We accomplished this by inverting the drug dissolution prob

231 A major way ISIS accomplished this was by adopting Hollywood-style narrat

232 Here, we ask how mtClpX accomplishes this activation.

233 How EMC accomplishes this feat has been unclear.

234 (Altered Chromatin COnformation STatistics) accomplishes this goal by extending the statistical mode

235 NS1 accomplishes this role through numerous interactions wit

236 How Rrp6p accomplishes this task is not understood.

237 ing cell-based therapies hold the promise of accomplishing this goal and, therefore, improving qualit

238 and deployment of a COVID-19 vaccine and how accomplishing this goal could compromise ethical princip

239 A common way of accomplishing this is to generate viral pseudoparticles

240 here exist effective experimental methods of accomplishing this, such as cell sorting and baiting; ho

241 via the immobilized AQDS/AH(2)QDS couple was accomplished through a combination of diffusion and elec

242 This is most often accomplished through a pathway called antigen cross-pres

243 amyloid formation in higher organisms can be accomplished through alternative splicing.

244 azolopyrazinyl series of TYK2 inhibitors was accomplished through computational and structurally enab

245 s from breaching the mucosal layer, which is accomplished through crosstalk with enterocytes and othe

246 nal stress-induced subcellular adaptation is accomplished through dynamic cytoskeletal reorganization

247 quired; and (2) generalization of CCD can be accomplished through integration mechanisms that link pa

248 ing this patient heterogeneity has also been accomplished through precision therapeutics, in which pe

249 tion of species-specific innate behaviors is accomplished through progressive modifications of pre-ex

250 This is accomplished through the activation of the master regula

251 Reprogramming is accomplished through the interplay of transcription fact

252 This transformation was accomplished through the introduction of a new strategy

253 ydrofunctionalization of terminal alkynes is accomplished through the reductive three-component coupl

254 n in regeneration-competent organisms can be accomplished through the remodeling of gene expression i

255 This endeavor may be accomplished through the study of patients, animal model

256 ulfase (iduronate-2-sulfatase, I2S) has been accomplished through the use of hydrogen-deuterium excha

257 problem-this is what the brain must actually accomplish to support perception and action.

258 COF-DB, the further metalation of COF-DB was accomplished upon the complexation with seven divalent t

259 tive tissue/other when ridge preservation is accomplished using a bovine versus a porcine xenograft.

260 The synthesis of PLM anchor was accomplished using a convergent block synthetic approach

261 3:7 and H(2)O/EtOH 7:3) and extractions were accomplished using a microwave apparatus.

262 Lesion bypass is accomplished using a unique protein-template mechanism i

263 The extraction was accomplished using acetonitrile, methanol, water, ammoni

264 lation of indoline derivatives has also been accomplished using activated alkenes by varying the reac

265 l clinical control of its infection has been accomplished using beta-lactam antibiotics such as the p

266 In mice, lineage analysis has been accomplished using Cre recombinase to indelibly label a

267 activity at the homobenzylic position can be accomplished using dual organic photoredox/cobalt cataly

268 ference of differential misclassification is accomplished using filtered genotypes while implementing

269 ns, and solid-state defects, spin readout is accomplished using fluorescence on an optical cycling tr

270 of benzo-fused cyclic sulfonamides has been accomplished using low-valent titanium.

271 Disease diagnosis is generally accomplished using quantitative polymerase chain reactio

272 dolines with azabenzonorbornadienes has been accomplished using Rh-catalysis.

273 ive ligation of two 28-mer peptides has been accomplished using the Suzuki-Miyaura cross-coupling rea

274 Information extraction is usually accomplished via a combination of manual expert curation

275 onkeys, socially relevant face processing is accomplished via a distributed functional network that i

276 -diaryl-1H-pyrrole-3-carbonitriles have been accomplished via a Pd-catalyzed coupling of arylboronic

277 analytical tasks and format conversions are accomplished via a set of automated scripts that enable

278 V) and quantification of arsenic species was accomplished via calibration with one As form; as iAs (I

279 llable inline optical delay line, previously accomplished via engineered dispersion in optical materi

280 cally, dynamic covalent functionalization is accomplished via Meisenheimer complexes produced by reac

281 or pest resistance in crops and is routinely accomplished via transgenic modification of plants for c

282 role among the multifarious mechanisms that accomplish visual spatial attention.

283 ing in the axons, although how this could be accomplished was unclear.

284 d realization of an annulation reaction that accomplishes what previously established reactions do no

285 aeruginosa (PA) infections is challenging to accomplish with antibiotic therapies, mainly due to resi

286 reening and treatment, which will be hard to accomplish with current diagnostic tools.

287 sk that entails extensive human resources to accomplish with prediction markets and manual replicatio

288 Allylic C-H amination is currently accomplished with (sulfon)amides or carbamates.

289 itoring of low-abundant of target miRNAs was accomplished with a limit of detection as low as 5 pM.

290 In vivo, this can be accomplished with a single dose of p53 inhibitor at the

291 ; however, most of the work to date has been accomplished with ATs that are either naturally promiscu

292 rination with metal alkali fluoride has been accomplished with BINAM-derived bisurea catalysts, prese

293 late-stage functionalizations that cannot be accomplished with carbonaceous CPPs.

294 This formal homobenzylic oxidation is accomplished with high atom economy without the use of d

295 unds formed after heteroarylation was easily accomplished with iodine.

296 These high uptake capacities are accomplished with low heat of adsorption, a feature desi

297 deposition inhibition and efflux enhancement accomplished with our novel multifunctional biomimetic n

298 Hence, the first aim accomplished with this study was the identification of t

299 FFPE blocks to sequence-ready library can be accomplished within 4 d.

300 This is accomplished without any peptide-level fractionation or