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1 sis either excited or inhibited striatal and accumbal activity but excitatory effects predominated in
2                  Using microdialysis, direct accumbal administration of 1 muM 6c reduced dopamine ove
3 nvestigate the effects of systemic and intra-accumbal administration of the CB1 antagonist SR141716A
4  the dopamine precursor DOPA following intra-accumbal administration of the DOPA decarboxylase inhibi
5 cortex via antidromic stimulation of cortico-accumbal afferents.
6 nfrontation, points to a significant role of accumbal and cortical DA and 5-hydroxytryptamine in the
7                                              Accumbal and pallidal levels of DeltaFosB were increased
8 ing effects in frontal, parietal, occipital, accumbal and thalamic regions.
9        They also suggest that improvement of accumbal antioxidant function may be a feasible approach
10    Here, we identify a functionally distinct accumbal astrocytic ensemble, associated with the ventra
11 nsmission in these cells, demonstrating that accumbal cholinergic neuronal activity regulates depress
12 epression-like behaviors and suggesting that accumbal CIN activity is crucial for the regulation of m
13 ), we identified anomalies within the fronto-accumbal circuit in childhood ADHD, which were associate
14 tistical modeling, indicates that the fronto-accumbal circuit is an important substrate of aggression
15  that strategies aimed at probing the fronto-accumbal circuit may be beneficial for the treatment of
16 e documented the relationship between fronto-accumbal circuitry-a critical cortical pathway to subcor
17    These findings suggest that disruption of accumbal core NMDA receptor-dependent plasticity may rep
18                                Excitation of accumbal D2 cells governs vital actions, including avoid
19 enhance psychostimulant-induced increases in accumbal DA and locomotor activity, we theorized that pe
20                               A reduction in accumbal DA content as determined by liquid chromatograp
21 dopaminergic state, characterized by blunted accumbal DA efflux and attenuated locomotor sensitizatio
22 ls, yet greater cocaine-induced increases in accumbal DA efflux.
23                              The increase in accumbal DA in aggressive animals supports the hypothesi
24 nted locomotor sensitization and lower basal accumbal DA levels, yet greater cocaine-induced increase
25 agents or vehicle, no significant changes in accumbal DA were observed.
26 t not the agonist, significant elevations of accumbal DA were observed.
27                                              Accumbal deep brain stimulation (DBS) is a promising the
28                     Our results suggest that accumbal dopamine and acetylcholine dynamics are largely
29 these hypotheses by simultaneously recording accumbal dopamine and acetylcholine signals in rats exec
30 ment in rats depends on interactions between accumbal dopamine and glutamate systems that are mediate
31                         Our data reveal that accumbal dopamine concentrations decrease proportionally
32 adox that cocaine more effectively increases accumbal dopamine despite identical effects on the dopam
33 is effect may represent different aspects of accumbal dopamine function.
34 These data support previous studies in which accumbal dopamine is required for producing a normal loc
35 were accompanied by a selective reduction in accumbal dopamine levels during reward consumption in mu
36 ey have been implicated in the regulation of accumbal dopamine levels.
37 rs (GlyRs) are involved in the regulation of accumbal dopamine levels.
38 lity of D1 activity in the mPFC to influence accumbal dopamine levels.
39 tine locomotor sensitization correlated with accumbal dopamine modulation by nicotine and mecamylamin
40 re, we investigated the presence of GlyRs in accumbal dopamine receptor medium spiny neurons (MSNs) o
41 n inhibitory control by prefrontal cortex on accumbal dopamine release during amygdala activation.
42 changes in tonic VTA activity and associated accumbal dopamine release help regulate motivational beh
43 ide an extended, comprehensive framework for accumbal dopamine release in behavioral control.
44 ticipation, and interaction resulted in more accumbal dopamine release than the same events directed
45                               An increase in accumbal dopamine release was observed during the stimul
46 tion via a concomitant active suppression of accumbal dopamine release.
47 r no change in basal levels of extracellular accumbal dopamine resulting from repeated psychostimulan
48 deletion of DGLalpha impairs the transfer of accumbal dopamine signaling from a reward to its earlies
49 try, we determined that the concentration of accumbal dopamine time-locked to cue presentation decrea
50                This inhibitory modulation of accumbal dopamine was receptor-specific, as the decrease
51 vestigated the impact of NPAS2 disruption on accumbal excitatory synaptic transmission and strength,
52  findings provide novel insights implicating accumbal Gln and Glu balance on the prediction of specif
53             Our results indicate that higher accumbal Gln-to-Glu ratio predicts better overall perfor
54      This model-based analysis revealed that accumbal Gln-to-Glu ratio specifically relates to stamin
55                                 In contrast, accumbal glutamate release was determined using individu
56 in mice, we simultaneously recorded from two accumbal glutamatergic afferents to assess circuit speci
57 term potentiation (LTP) of the frontocortico-accumbal glutamatergic synapses correlates with PSD-95 r
58  the form of long-term depression at cortico-accumbal glutamatergic synapses.
59                                 In addition, accumbal GRIP deletion was associated with blunted long-
60 is the first study to demonstrate a role for accumbal GRIP in behavior.
61 ur data indicate a close association between accumbal GSH levels and an individual's capacity to exer
62 rodent populations, we establish that higher accumbal GSH levels are highly predictive of better, and
63 he GSH precursor N-acetyl-cysteine increased accumbal GSH levels in rats and led to improved performa
64 hese data argue against a protective role of accumbal indirect pathway D2Rs in alcohol consumption bu
65                                        Intra-accumbal infusion of PFI3 attenuated, whereas viral over
66                           Systemic and intra-accumbal inhibition of BRD4 with the BET inhibitor, JQ1,
67                           Furthermore, intra-accumbal inhibition of GluN2C/2D-containing receptors an
68 B) in the nucleus accumbens (NAc), and intra-accumbal injection of cocaine- and amphetamine-regulated
69  in nicotine-conditioned reward as the intra-accumbal injection of the selective alpha6beta2* alpha-c
70 cocaine-seeking behaviors after either intra-accumbal injections of the BRG1 inhibitor PFI3 or viral-
71            Chemogenetic silencing of thalamo-accumbal inputs rescued PCP-induced sociability deficits
72                Although ZIP has no effect on accumbal LTD in slices from naive or yoked saline mice,
73 pe-specific shift in glutamatergic inputs to accumbal medium spiny neurons.
74      Our results implicate a causal role for accumbal MFN2 on the regulation of anxiety and depressio
75     Subsequent experiments showed that intra-accumbal microinjection of AP-5 alone dose-dependently r
76      These findings suggest that deficits in accumbal monoamine release may contribute to the negativ
77       These data rule out the involvement of accumbal NET or SERT in the cocaine-induced increase in
78 , 1028 enhances MSN excitability ex vivo and accumbal neuron firing rate in vivo in murine models.
79 Thus, although ACh can modulate striatal and accumbal neuronal activity, DA does not regulate this ef
80                  We find that select thalamo-accumbal neuronal ensembles become profoundly hypoactive
81               Impairments in sociability and accumbal neuronal excitability are prevented by normaliz
82  conditioned approach behavior as well as on accumbal neuronal responses time locked to the CS+, the
83 imulus (CS) effects by selectively enhancing accumbal neuronal responses to stimuli.
84 overexpress mutant and WT alpha1 subunits in accumbal neurons in D1 Cre and alpha1 KI mice.
85                                           In accumbal neurons in vivo, CaMKIIalpha is recruited to D3
86 ation of the ethanol sensitivity in isolated accumbal neurons indicated that the GlyRs phenotype chan
87 ve to ethanol, has been recently reported in accumbal neurons suggesting that they are protective aga
88  for the complex response of neostriatal and accumbal neurons to systemic AMPH administration.
89 applied iontophoretically to neostriatal and accumbal neurons under naturally occurring behavioral co
90 er, ethanol-sensitized mice also had reduced accumbal NMDA receptor function and expression, as well
91               Furthermore, systemic or intra-accumbal opioid injections rapidly dysregulate thalamost
92 ase motivation for food reward by modulating accumbal or striatal dopamine release.
93  examine the functional relationship between accumbal oxytocin receptor density and social behavior i
94 n nonmonogamous rodent species, and blocking accumbal oxytocin receptors prevents mating-induced part
95 her reveal persistent adaptations at thalamo-accumbal parvalbumin interneuronal synapses, whereas fun
96 eveal that thalamostriatal neurons innervate accumbal parvalbumin interneurons through synapses enric
97 ucrose by activating the mesolimbic dopamine-accumbal pathway, solely based on calorie load.
98  and physiological properties of the cortico-accumbal pathway.
99                       However, the effect on accumbal population activity remains elusive.
100                  These results indicate that accumbal population dichotomy is dynamic and contains a
101                                        Intra-accumbal PTX produced a dose-dependent increase in locom
102                                        Intra-accumbal PTX sensitized rats to the locomotor-activating
103 sive stimuli, where females showed a greater accumbal response.
104 ith a selective increase in the magnitude of accumbal responses during the CS+.
105 fect the conditioned behavior, but increased accumbal responses to the CS+.
106  pavlovian conditioned stimuli by amplifying accumbal responses to those stimuli.
107                     No concurrent changes in accumbal serotonin levels were seen during or after the
108  neostriatum, an abrupt increase occurred in accumbal shell, a limbic-related area implicated in goal
109 routing, to the synaptic connectivity of the accumbal shell.
110  of protein kinase targets in mouse striatal/accumbal slices revealed that NMDAR activation resulted
111              The age-dependent alteration of accumbal structure was associated with qualitatively dif
112 eptor binding was determined in striatal and accumbal tissue samples.
113 neous GABA ion channel opening and increased accumbal tonic current.
114  Opposite-sex pair bonding led to changes in accumbal transcription that were stably maintained while
115 ormalized PCP-induced impairments in thalamo-accumbal transmission and sociability deficits.
116 clidine (PCP)-induced impairments in thalamo-accumbal transmission and sociability deficits.
117 that activation of mGlu(3) decreases thalamo-accumbal transmission and thereby rescues sociability de
118 ach was used to evaluate the role of thalamo-accumbal transmission in PCP-induced sociability deficit
119 ect mediated by the relationship between the accumbal volume and impulsivity.
120                         The magnitude of the accumbal volume reductions within the ADHD group was sig
121 lly, children with ADHD showed reduced right accumbal volumes and frontal-accumbal white matter conne
122 explained by multivariate measures of fronto-accumbal white matter connectivity and cortical thicknes
123 d reduced right accumbal volumes and frontal-accumbal white matter connectivity compared with HC.
124                    We demonstrate that intra-accumbal ZIP administration blocks cocaine-primed RI in
125                          We found that intra-accumbal ZIP blocked RI of cocaine seeking 24 h and 1 we
126        These findings demonstrate that intra-accumbal ZIP persistently reverses cocaine-induced behav

 
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