ライフサイエンスコーパス: accumbens

1 medial prefrontal cortex (vmPFC) and nucleus accumbens).

2 egulation of dopamine release in the nucleus accumbens.

3 from activity across the VTA and the nucleus accumbens.

4 on of cocaine potency at DATs in the nucleus accumbens.

5 utamatergic hippocampal outputs onto nucleus accumbens.

6 y enhanced dopamine signaling in the nucleus accumbens.

7 rd processing within the caudate and nucleus accumbens.

8 P-32 phosphorylation at Thr75 in the nucleus accumbens.

9 ulation of oxytocin terminals in the nucleus accumbens.

10 pressing medium spiny neurons in the nucleus accumbens.

11 ecting to lateral or medial shell of nucleus accumbens.

12 ting D(1)-mediated excitation in the nucleus accumbens.

13 gth in the ventral hippocampal output to the accumbens.

14 D1-MSNs and D2-MSNs mediate output from the accumbens.

15 ract with distinct subregions of the nucleus accumbens.

16 and posterior), caudate nucleus and nucleus accumbens.

17 mediator of cocaine responses in the nucleus accumbens.

18 (VTA), with no apparent input to the nucleus accumbens.

19 nterior limb of the internal capsule/nucleus accumbens.

20 GS12-null mice are restricted to the nucleus accumbens.

21 urements of dopamine dynamics in the nucleus accumbens.

22 This effect is prominent within the nucleus accumbens, a brain region associated with mood regulatio

23 ceptors on astrocytes located in the nucleus accumbens, a key structure of the brain's reward system.

24 1 medium spiny neurons (MSNs) in the nucleus accumbens-a population that has been linked to reward-dr

25 in the dorsal striatum (DS) and the nucleus accumbens (Acb) jointly but differentially contribute to

26 We identified a cell type in the nucleus accumbens activated downstream of long-range excitatory

27 xperiment, we show that learning and nucleus accumbens activation in a simple unidimensional reinforc

28 ositive correlation with caudate and nucleus accumbens activity during placebo, which was absent afte

29 m administration reduced caudate and nucleus accumbens activity during reward outcome.

30 ce for co-use differences related to nucleus accumbens activity during reward processing.

31 developing chronic pain and altered nucleus accumbens activity is a signature of the state of chroni

32 Es and did so more robustly than the nucleus accumbens, an input to the VP.

33 displayed blunted reactivity in the nucleus accumbens and amygdala.

34 ively correlated with gaze duration (nucleus accumbens and anterior insular cortex), while two compon

35 onal connectivity locally within the nucleus accumbens and basal forebrain, and reversed the gamma an

36 n functional connectivity within the nucleus accumbens and basal forebrain.

37 at the connectivity patterns for the nucleus accumbens and cortico-striatal motor circuits (posterior

38 ural spine plasticity changes in the nucleus accumbens and depressive-like behavior.

39 oked transcriptional changes in both nucleus accumbens and dorsal striatum, dramatically increasing d

40 ide transcriptional profiling in the nucleus accumbens and dorsal striatum.

41 (1)H-MRS) at ultra-high-field in the nucleus accumbens and inquired whether levels of glutamate (Glu)

42 amine and glutamate microdialysis in nucleus accumbens and medial prefrontal cortex, and ex vivo stri

43 receptor subunit mRNA levels in the nucleus accumbens and medial prefrontal cortex.

44 ) and reward systems (orbital gyrus, nucleus accumbens and putamen) in driving pre-training diagnosti

45 tivity changes were observed between nucleus accumbens and rostral anterior cingulate cortex in the p

46 ional connectivity between bilateral nucleus accumbens and rostral anterior cingulate cortex were ass

47 The reduced metabolism in nucleus accumbens and the disrupted thalamo-accumbens connectivi

48 ivity of striatal (caudate, putamen, nucleus accumbens) and cortical (insula, anterior cingulate cort

49 d on the function of the mesolimbic (nucleus accumbens) and nigrostriatal (dorsal striatum) dopamine

50 ons, including the caudate, putamen, nucleus accumbens, and globus pallidus.

51 ivation of oxytocin receptors in the nucleus accumbens, and is recapitulated by stimulation of oxytoc

52 brain regions (ventral hippocampus, nucleus accumbens, and medial prefrontal cortex) of susceptible,

53 ncing in the ventral tegmental area, nucleus accumbens, and prefrontal cortex of male and female mice

54 tructures involving the hippocampus, nucleus accumbens, and prefrontal cortex.

55 , attenuated dopamine release in the nucleus accumbens, and reduced cocaine-seeking behavior.

56 st areas except for the hippocampus, nucleus accumbens, and thalamus.

57 egulation of Gadd45b mRNA in the rat nucleus accumbens, and that knockout or site-specific CRISPR/Cas

58 obus pallidus internus (GPi) (n=47), nucleus accumbens/anterior limb of the internal capsule (n=4) or

59 These results point to Cdk5 in the nucleus accumbens as a critical contributor to depressive-like b

60 thway tracing analyses implicate the nucleus accumbens as a putative downstream target of vHP MCH1 re

61 ty and suggest this mechanism in the nucleus accumbens as a target for ethanol modulation of reward.

62 m the anterior insular cortex to the nucleus accumbens as modulating highly compulsive-like food self

63 ostral medial frontal gyrus and left nucleus accumbens as well as right frontal pole and left caudate

64 ocaine potency at distal DATs in the nucleus accumbens as well as the behavioral economics of cocaine

65 hippocampus, prefrontal cortex, and nucleus accumbens) as well as chromatin accessibility in the lat

66 transiently increased synaptic proximity of accumbens astrocytes.

67 reward-aversion brain centers (i.e., nucleus accumbens, bed nucleus of the stria terminalis, amygdala

68 tivation of the basolateral amygdala-nucleus accumbens (BLA-NAc) glutamatergic circuit reduced SI and

69 ly elevated dopamine overflow in the nucleus accumbens, but not prefrontal cortex, without influencin

70 neuromodulatory signaling within the nucleus accumbens, but the neuronal dynamics underlying this beh

71 synapses, which are generated in the nucleus accumbens by cocaine self-administration, and subsequent

72 es not elicit differences in overall nucleus accumbens Ca(2+) activity.

73 tromedial prefrontal cortex (vmPFC), nucleus accumbens, caudate nucleus, and putamen.

74 d significant negative dose-response for the accumbens, caudate, pallidum, putamen and ICV (P = 0.003

75 her in SAD patients in the amygdala, nucleus accumbens, caudate, putamen, and posterior ventral thala

76 king relates to activity in specific VTA and accumbens compartments, how these change for different f

77 nucleus accumbens and the disrupted thalamo-accumbens connectivity (enhanced negative connectivity)

78 MPH's normalization of thalamo-accumbens connectivity (reduced negative connectivity) b

79 k pain patients showed altered local nucleus accumbens connectivity between putative shell and core,

80 In two experiments, we induced nucleus accumbens core (NAcc) dysfunction in rats receiving fear

81 as highlighted the importance of the nucleus accumbens core (NAcC) in behavioral tasks dependent on e

82 we examined a possible role for the nucleus accumbens core (NAcc) in the acquisition and expression

83 o perform.SIGNIFICANCE STATEMENT The nucleus accumbens core (NAcC) is essential to process informatio

84 nvestigated the DNA methylome of the nucleus accumbens core (NAcc) of rhesus macaques after chronic a

85 e basolateral amygdala (BLA) and the nucleus accumbens core (NAcC).

86 The nucleus accumbens core (NAcore) contains two predominate neurona

87 SP) at glutamatergic synapses in the nucleus accumbens core (NAcore).

88 prelimbic cortex that project to the nucleus accumbens core (PrL->NAcC).

89 ulated by synaptic plasticity in the nucleus accumbens core and involves distinct plasticity in D(1)

90 of D2R and D1R antagonists into the nucleus accumbens core and shell (NAcC; NAcS), the anterior and

91 erences in dopamine signaling in the nucleus accumbens core at baseline, in response to a single dose

92 While PL projections to nucleus accumbens core have been shown to be involved in driving

93 ne to inhibit dopamine uptake in the nucleus accumbens core using fast scan cyclic voltammetry ex viv

94 mouse dorsolateral striatum, but not nucleus accumbens core, is governed by GAT-1 and GAT-3.

95 he ventral striatum (medial accumbens shell, accumbens core, lateral accumbens shell) and showed comp

96 , prelimbic, and infralimbic cortex; nucleus accumbens core, medial shell, and lateral shell; anterio

97 These regions, comprising the nucleus accumbens core, shell, and caudate-putamen, are instrume

98 nriched in dorsolateral striatum compared to accumbens core.

99 d with transient synaptic enlargement in the accumbens core.

100 ied medium spiny neurons (MSNs) in the adult accumbens core.

101 gulate cortices, caudate nucleus and nucleus accumbens (corrected P = 0.043).

102 These data show that, although accumbens D1-MSNs largely collateralize to both the vent

103 s were tested for their locomotor or nucleus accumbens dopamine (NAcc DA) response to amphetamine or

104 riction during adolescence decreased nucleus accumbens dopamine release.

105 d tyrosine hydroxylase levels in the nucleus accumbens, dorsal putamen and caudate using immunohistoc

106 he bilateral ventral caudate and the nucleus accumbens during reward receipt relative to loss.

107 NA-mediated knockdown of Lmo4 in the nucleus accumbens enhanced alcohol consumption, whereas knockdow

108 evealed that dopamine release in the nucleus accumbens evoked by reward-predictive cues is accompanie

109 acute increase in the slope and amplitude of accumbens evoked responses, but no long-term changes wer

110 GPi, globus pallidus internus; NAc, nucleus accumbens) evoked a sufficiently distinctive blood-oxyge

111 While nucleus accumbens excitatory synaptic plasticity is well-charact

112 changes in lipid composition of the nucleus accumbens from mice subjected to two lipid diets.

113 e D3 receptors protein levels in the nucleus accumbens, frontal cortex and putamen were determined us

114 hesis posits neuronal inhibitions in nucleus accumbens generate intense motivation.

115 s, suggesting a complete recovery of nucleus accumbens glutamatergic synaptic plasticity when dopamin

116 activation of the VTA-GABA terminals in the accumbens had no effect on any of these behaviors.

117 ns from the prefrontal cortex to the nucleus accumbens has been argued to underlie motivational disor

118 signals in areas which included the nucleus accumbens in 475 participants.

119 d negative connectivity between thalamus and accumbens in CUD was normalized by MPH (reducing negativ

120 ions in medial prefrontal cortex and nucleus accumbens in human MDD and the 3 mouse chronic stress mo

121 Substantial evidence implicates the nucleus accumbens in motivated performance, but very little is k

122 task and (2) dopamine release in the nucleus accumbens in response to electrical stimulation of the V

123 th hyporeactivity exclusively in the nucleus accumbens in response to the anticipation of a reward, w

124 The nucleus accumbens is a critical integration center for reward-re

125 ampal outputs to medium spiny neurons of the accumbens may be key sites for the formation and storage

126 results may be relevant to roles of nucleus accumbens mechanisms in pathological motivations, includ

127 edium spiny neurons (D1-MSNs) in the nucleus accumbens medial shell (NAcmSh), and with lateral hypoth

128 ehavior, with a specific emphasis on nucleus accumbens medial shell and stress responsivity.

129 eward-related regions, including the nucleus accumbens, medial prefrontal cortex, and orbitofrontal c

130 volumes, most prominent in thalamus, nucleus accumbens, medial temporal, medial prefrontal/frontal an

131 Subtypes of nucleus accumbens medium spiny neurons (MSNs) promote dichotomou

132 seen specifically on the inputs from nucleus accumbens medium spiny neurons expressing either the D1

133 s from the ventral tegmental area to nucleus accumbens (mesolimbic circuit) and frontal cortex (mesoc

134 gnaling in the reward circuit is the nucleus accumbens, more specifically, the dopamine D1 receptor-e

135 er GLT-1 and glutamate efflux in the nucleus accumbens (NA) core during the reinstatement of cocaine-

136 In the nucleus accumbens (NAc) activation of oxytocin receptors (OTR) p

137 In rodents, nucleus accumbens (NAc) afferents from the ventral hippocampus (

138 es in the proteomic landscape in the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC) were

139 gh effects on dopamine output in the nucleus accumbens (NAc) and on neurotransmission in the ventral

140 o record haemodynamic signals in the nucleus accumbens (NAc) and orbitofrontal cortex (OFC), while fr

141 onal and morphological events in the nucleus accumbens (NAc) and other brain reward regions contribut

142 ta (IGF-1Rbeta) were assessed in the nucleus accumbens (NAc) and ventral tegmental area (VTA) of vehi

143 human postmortem brain, focusing on nucleus accumbens (NAc) as a key brain region in developing and

144 antagonist (DNQX) in medial shell of nucleus accumbens (NAc) can cause either intense appetitive moti

145 sponse 3) is oppositely regulated in nucleus accumbens (NAc) cell subtypes 24 hours following cocaine

146 The nucleus accumbens (NAc) controls multiple facets of impulsivity

147 was increased in D1+ neurons in the nucleus accumbens (NAc) core and dorsolateral (DLS) striatum in

148 ns with divergent projections to the nucleus accumbens (NAc) core and shell.

149 ventromedial striatum, including the nucleus accumbens (NAc) core, is typically associated with limbi

150 avior is known to be mediated by the nucleus accumbens (NAc) core.

151 NT Glutamatergic transmission in the nucleus accumbens (NAc) critically contributes to goal-directed

152 Here we studied the role of nucleus accumbens (NAc) dopamine receptor (Drd)1- and Drd2-expre

153 plex circuit interactions within the nucleus accumbens (NAc) facilitate goal-directed behavior.

154 e individuals remains ambiguous, the nucleus accumbens (NAc) has been shown to play a central role.

155 olinergic interneurons (ChIs) in the nucleus accumbens (NAc) have been implicated in drug addiction,

156 NCE STATEMENT Given the roles of the nucleus accumbens (NAc) in integrating cortical and allocortical

157 vmPFC with different outputs to the nucleus accumbens (NAc) in male and female rats.

158 ed the role of stress systems in the nucleus accumbens (NAc) in promoting sex differences in the rein

159 Here we studied the role of the nucleus accumbens (NAc) in this model.

160 onditions.SIGNIFICANCE STATEMENT The nucleus accumbens (NAc) is a key part of the striatal limbic ter

161 The nucleus accumbens (NAc) is a mesocorticolimbic structure that in

162 The nucleus accumbens (NAc) is a reward processing hub sensitive to

163 e reward circuitry, within which the nucleus accumbens (NAc) is anatomically positioned as an interfa

164 ted whether GSK3beta activity in the nucleus accumbens (NAc) is associated with depression-like behav

165 from ventral tegmental area (VTA) to nucleus accumbens (NAc) is critical for motivation to work for r

166 The nucleus accumbens (NAc) is essential for cued approach behavior

167 The nucleus accumbens (NAc) is part of a brain reward circuit affect

168 CP-AMPARs in the nucleus accumbens (NAc) mediate cue-triggered motivation for foo

169 n in the prefrontal cortex (PFC) and nucleus accumbens (NAc) of mice exposed to multimodal chronic re

170 ine on rapid dopamine signals in the nucleus accumbens (NAc) of rats.

171 the ventral tegmental area (VTA) or nucleus accumbens (NAc) of the mesolimbic DA system.

172 te projections from the vHipp to the nucleus accumbens (NAc) or prefrontal cortex (mPFC).

173 Within this circuit, two distinct nucleus accumbens (NAc) output neuron types, dopamine D1 or D2 r

174 cate the insular cortex (IC) and the nucleus accumbens (NAc) play important roles in social behaviors

175 pus (vHPC) neurons projecting to the nucleus accumbens (NAc) regulates mood-related behavioral respon

176 (FC) of reward neurocircuitry using nucleus accumbens (NAc) seed regions of interest, and then chara

177 We then quantified DA release in the nucleus accumbens (NAc) shell after treatment with d-Amphetamine

178 a (VTA), central amygdala (CeA), and nucleus accumbens (NAc) shell had no such effect.

179 The nucleus accumbens (NAc) shell, which integrates the aversive and

180 ctivity in DA terminals in different nucleus accumbens (NAc) subnuclei during an aversive and reward

181 timately depends on strengthening of nucleus accumbens (NAc) synapses through an accumulation of high

182 rom dorsal CA1 (dCA1) hippocampus to nucleus accumbens (NAc) that enables the behavioral manifestatio

183 of CINs in both dorsal striatum and nucleus accumbens (NAc) through activation of CRF type 1 recepto

184 t medium spiny neurons (MSNs) in the nucleus accumbens (NAc) undergo structural plasticity; however,

185 Energy metabolic changes in the nucleus accumbens (NAc) were recently related to hierarchical st

186 medial prefrontal cortex (vmPFC) and nucleus accumbens (NAc)).

187 The nucleus accumbens (NAc), a central component of the midbrain dop

188 medium spiny neurons (MSNs) from the nucleus accumbens (NAc), a hub of the brain's motivation system.

189 the expression of the lncRNA Gas5 in nucleus accumbens (NAc), a key brain reward region, of adult mal

190 ely behaving mice, astrocytes in the nucleus accumbens (NAc), a key reward center in the brain, respo

191 e mammalian forebrain, including the nucleus accumbens (NAc), a major neural substrate of motivated a

192 behaviors through its action in the nucleus accumbens (NAc), but the impact of NPY on the human NAc

193 The nucleus accumbens (NAc), considered the hub of reward circuitry,

194 prefrontal cortex (mPFC), but not to nucleus accumbens (NAc), contributed to the antidepressive-like

195 In the nucleus accumbens (NAc), structural and physiological plasticity

196 CRH(+) fibers are found in nucleus accumbens (NAc), where CRH modulates reward/motivation b

197 hronic cocaine exposure in the mouse nucleus accumbens (NAc)-a key reward region of brain.

198 ons form functional connections with nucleus accumbens (NAc)-projecting neurons of the posterior port

199 eases AMPAR-mediated currents in the nucleus accumbens (NAc).

200 food (HPF), which is mediated by the nucleus accumbens (NAc).

201 lease from their distal terminals in nucleus accumbens (NAc).

202 rphine and cocaine abstinence in the nucleus accumbens (NAc).

203 n medium spiny neurons (MSNs) of the nucleus Accumbens (nAc).

204 ral OFC (BA47), head of caudate, and nucleus accumbens (NAc).

205 s (DORs), are highly enriched in the nucleus accumbens (NAc).

206 d mesolimbic networks, including the nucleus accumbens (NAc).

207 al nucleus of the amygdala (CeA) and nucleus accumbens (NAc).

208 ractions between the hippocampus and nucleus accumbens (NAc).

209 Finally, patch recordings in nucleus accumbens (NAcc) medium spiny neurons (MSNs) revealed re

210 nt of non-drug rewards by increasing nucleus accumbens (NAcc) reactivity to anticipatory cues.

211 ems on adolescent depression through nucleus accumbens (NAcc) volume alteration, but not through the

212 functional connectivity between the nucleus accumbens (NAcc), a key structure of the reward system,

213 la, anterior cingulate cortex (ACC), nucleus accumbens (NAcc), and orbitofrontal cortex (OFC).

214 dance responses [bilateral amygdala, nucleus accumbens (NAcc), and ventromedial prefrontal cortex (PF

215 mes of the hippocampus, thalamus and nucleus accumbens (NAcc)-three subcortical regions selected for

216 composition both in the PFC and the nucleus accumbens (NAcc).

217 ons (i.e., increased activity in the nucleus accumbens [NAcc] and medial prefrontal cortex [MPFC] as

218 ard-related brain regions (e.g., the nucleus accumbens [NAcc]) and unhealthy eating behaviors and out

219 ~1% of neurons in the core subregion of the accumbens (NAcore) activated during cue-induced seeking

220 ons during which corticothalamic and thalamo-accumbens neural activity was altered using chemogenetic

221 restructuring of dendritic spines of nucleus accumbens neurons is thought to be one of the cellular s

222 of total spine number in a subset of nucleus accumbens neurons that prevents stress-related electroph

223 catalytic activity communicates with nucleus accumbens neurons to induce t-SP and cocaine seeking.

224 the ventral tegmental area (VTA) or nucleus accumbens neurons, but less is known about cocaine-induc

225 reas (putamen (PT), caudate nucleus (CN) and accumbens nucleus (NAC)) from postmortem brain tissue we

226 These activated regions include accumbens nucleus, caudate putamen, claustrum, bed nucle

227 areas of the reward circuit such as VTA and accumbens nucleus.

228 efflux in the prefrontal cortex and nucleus accumbens of conscious rats were assessed using microdia

229 Microinjections in nucleus accumbens of glutamate antagonist, DNQX, which might sup

230 y in spiny projection neurons in the nucleus accumbens of mice during learning.

231 el activated neural ensembles in the nucleus accumbens of the mouse brain during brief stimulation of

232 ression-medial prefrontal cortex and nucleus accumbens-of humans with MDD and of 3 chronic stress mod

233 effect of ZIP administration in the nucleus accumbens on reinstatement (RI) of cocaine seeking, a ro

234 eflected this interaction, while the nucleus accumbens only reflected uncertainty.

235 st research demonstrates that in the nucleus accumbens, opioid-induced excitatory synaptic plasticity

236 family regulates activity within the nucleus accumbens or behavioral responses to drugs of abuse.

237 of the internal capsule (ALIC), the nucleus accumbens or the subthalamic nucleus (STN).

238 n, globus pallidus, hippocampus, and nucleus accumbens) other than amygdala volume.

239 d in the pair-bonding process in the nucleus accumbens, our work illustrates the vast extent of sex d

240 acute oxycodone-induced decreases in nucleus accumbens oxygen levels.

241 tices, and between orbitofrontal and nucleus accumbens, predict individual differences in sensibility

242 munoreactive (Fos-ir) neurons in the nucleus accumbens predicted the frequency of the feeding of the

243 mine the role of corticothalamic and thalamo-accumbens projections in the augmentation of heroin seek

244 summatory behavior, with particular focus on accumbens projections to the lateral hypothalamus.

245 We found that activity in the nucleus accumbens promotes cheating, particularly for individual

246 In the nucleus accumbens, protein restriction in adults increased dopam

247 d that PVT neurons projecting to the nucleus accumbens (PVT-NAc) develop inhibitory responses to rewa

248 egions associated with reward (i.e., nucleus accumbens, r = 0.24), memory (i.e., hippocampus, r = 0.3

249 ctivation in reward-related regions (nucleus accumbens, r = 0.29; caudate nucleus, r = 0.27) to unhea

250 ior limb of the internal capsule and nucleus accumbens region (ALIC-NAcc) on OCD symptoms, executive

251 Glutamatergic synapses in the nucleus accumbens regulate the motivation to relapse to opioid u

252 bed nucleus of stria terminalis and nucleus accumbens) remains investigational.

253 Is neuronal inhibition in nucleus accumbens required for such pharmacologically-induced mo

254 sis of the power spectral density of nucleus accumbens resting-state activity in the subacute and chr

255 ion of OFC neurons projecting to the nucleus accumbens selectively disrupted performance following a

256 ntal cortex (mPFC) projecting to the nucleus accumbens shell (AcbSh) in female Sprague Dawley rats.

257 sory, and limbic information, to the nucleus accumbens shell (an area known to be important for rewar

258 n from the infralimbic cortex to the nucleus accumbens shell (IL-NAc) is thought to inhibit cocaine s

259 ver subcortical regions, such as the nucleus accumbens shell (NAcS) and basolateral amygdala, which e

260 le Long-Evans rats to test if phasic nucleus accumbens shell (NACs) dopamine dynamics are associated

261 t and higher MSN excitability in the nucleus accumbens shell (NAcS).

262 Pharmacological manipulations of the nucleus accumbens shell (NAcSh) have repeatedly been demonstrate

263 mised signaling between the mPFC and nucleus accumbens shell (NAcSh) is thought to underlie the cogni

264 that cocaine-induced hypoactivity of nucleus accumbens shell (NAcSh) medium spiny neurons (MSNs), one

265 iated knockdown of G9a expression in nucleus accumbens shell (NAcSh) of male rats reduces both addict

266 gmental area (VTA) projection to the nucleus accumbens shell (NAcSh) regulates NAcSh-mediated motivat

267 ergic projections from the IL to the nucleus accumbens shell (NAcSh) suppresses the aversive impact o

268 glutamatergic synapses in the adult nucleus accumbens shell (NAcSh).

269 es, infusions of exendin-4 directly into the accumbens shell attenuated oxycodone self-administration

270 bic cortex and its projection to the nucleus accumbens shell in suppressing learned negative emotiona

271 cal activation of the infralimbic to nucleus accumbens shell pathway attenuates learned aversive resp

272 ate an important role for the PVT to nucleus accumbens shell projections in the augmentation of heroi

273 RNA-seq of the nucleus accumbens shell revealed hundreds of differentially regu

274 is, we implanted rats with electrodes in the accumbens shell to record synaptic potentials evoked by

275 ial accumbens shell, accumbens core, lateral accumbens shell) and showed complex and heterogeneous pr

276 binding across the ventral striatum (medial accumbens shell, accumbens core, lateral accumbens shell

277 Chemogenetic activation of thalamo-accumbens shell, but not core, projectors attenuated her

278 ductions in the cingulate cortex and nucleus accumbens shell, regardless of MIA timing; (2) SSTR2 mRN

279 dato-Putamen, DLS) and ventromedial (Nucleus Accumbens Shell, VS) striatal subregions was examined by

280 ive value and dopamine levels in the nucleus accumbens shell.

281 pressing medium spiny neurons in the nucleus accumbens shell.

282 hin DS synapses, but enhanced in the nucleus accumbens, suggesting a dichotomous role of BDNF signali

283 sporters on astroglial processes adjacent to accumbens synapses contributes to heroin seeking induced

284 Subcortical volumes (pallidum, nucleus accumbens, thalamus) were also different among groups, a

285 a discrete number of neurons in the nucleus accumbens that are causally linked to reward-related con

286 er dopamine receptor blockade in the nucleus accumbens; the D1R antagonist, SCH23390, in the NAcS and

287 Neural responses in the nucleus accumbens to anticipated reward and non-loss outcomes di

288 hways between the OFC, amygdala, and nucleus accumbens to reveal their separable contributions to rei

289 This led to a highly sexually biased nucleus accumbens transcriptome at 3 weeks related to processes

290 area, hypothalamus, rostral pallium, nucleus accumbens, ventral pallidum, and bed nucleus of the stri

291 results provide evidence that lower nucleus accumbens volume confers risk for developing chronic pai

292 The smaller accumbens volume was also observed in a separate cohort

293 oping chronic pain exhibit a smaller nucleus accumbens volume, which persists in the chronic phase, c

294 and greater lateral ventricle, caudate, and accumbens volumes (Cohen's d values, -0.90 to 0.93).

295 compared to controls, metabolism in nucleus accumbens was lower for the placebo and MPH measures, th

296 , prediction-error activation in the nucleus accumbens was similar across age groups, and numerically

297 nd transcriptomic regulations in the nucleus accumbens were measured by RNA sequencing.

298 exhibited higher SERT binding in the nucleus accumbens while DAT availability in the amygdala, hippoc

299 ith more focal hyporeactivity in the nucleus accumbens, while depression severity during early childh

300 derlie augmented connectivity of the nucleus accumbens with fear/anxiety regions, disrupting the func