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3 blation studies demonstrate that segregating acentrics are mechanically associated with microtubules.
6 uct of assembly is a holo-apoptosome with an acentric CARD-CARD disk and tethered pc-9 catalytic doma
9 Polo facilitate the accurate segregation of acentric chromatids by maintaining the integrity of the
11 function results in abnormal segregation of acentric chromatids, a decrease in acentric chromosome t
12 in cancer cells is often mediated by paired acentric chromatin bodies called double minute chromosom
14 ning bodies were formed through both loss of acentric chromosome fragments and by chromosome missegre
15 romosome condensation, an increased yield of acentric chromosome fragments at the first postirradiati
16 ules play a key role in poleward movement of acentric chromosome fragments generated in Drosophila me
21 gation of acentric chromatids, a decrease in acentric chromosome tethering, and a great reduction in
22 determine the behavior of kinetochore-free "acentric" chromosome fragments and "monocentric" chromos
23 polyploid, they naturally accumulate broken acentric chromosomes but do not apoptose/arrest the cell
24 lear envelope through which late-segregating acentric chromosomes enter the telophase daughter nucleu
32 ents that lack centromeric DNA (structurally acentric chromosomes) are usually not inherited in mitos
36 ormation of extrachromosomal DNAs (ecDNAs) - acentric, circular DNA molecules ranging from 50 kb to 5
37 cle morphology characterized by a spherical, acentric core and a crescent-shaped, electron-dense shel
38 e benzothiazolium crystals consisting of new acentric core HMB (2-(4-hydroxy-3-methoxystyryl)-3-methy
40 ogenic centromere-containing fragment and an acentric distal fragment, with both mis-segregated into
41 attempted to characterize MN with centric or acentric DNA fragments for the presence or absence of fr
42 ases to promote alignment and segregation of acentric DNA produced by double-strand breaks, thus avoi
45 h as temperature (T(c)) and pressure (P(c)), acentric factor (omega), boiling temperature (T(b)), and
48 ormation: following a double-strand break an acentric fragment forms, during either meiosis or mitosi
51 a- or metaphase were cut with the laser, the acentric fragments (lacking kinetochores) that were gene
52 chromosome fragmentation at metaphase I, and acentric fragments and chromatin bridges in meiosis I an
55 mosomes with live-cell imaging and show that acentric fragments cluster in close spatial proximity th
57 a single centromere, it remains unclear how acentric fragments derived from shattered chromosomes ar
58 it is unknown whether these late-segregating acentric fragments influence NEF to ensure their inclusi
59 tic clustering facilitates the reassembly of acentric fragments into rearranged chromosomes lacking t
65 broken chromosome (rejoining the centric and acentric fragments) occurred in either the mother or dau
66 or during prometaphase/metaphase II, whereas acentric fragments, also generated by afd1, fail to alig
67 ere given and chromosome damage (dicentrics, acentric fragments, micronuclei, chromatid gaps/breaks)
72 re squamous epithelial cells that contain an acentric, hyperchromatic nucleus that is displaced by a
76 a new general mechanism is proposed for the acentric inv dup marker formation: following a double-st
77 the previously suggested model by which the acentric inv dup markers form through inter-chromosomal
82 irst-order hyperpolarizabilities (beta) into acentric microstructures for electro-optic (EO) applicat
84 rmally non-centromeric DNAs present in these acentric mini-chromosomes have acquired centromere funct
85 elanogaster mini-chromosome, of structurally acentric mini-chromosomes that display efficient mitotic
88 to functional neocentromeres of structurally acentric minichromosomes; and (c) the localization of bo
90 normal virion maturation; virions containing acentric nucleoid structures comprised 90 to 99% of all
92 ivate new experimental approaches to achieve acentric order in both bulk-phase and thin film structur
96 that from the X-ray crystal structure of the acentric racemic (+/-)-(1pR,1' 'R)(1pS,1' 'S)-[Cr(CO)(3)
101 both, consistent with a model in which both acentric sister chromatid fragments are passaged into th
104 at the nanoscale can be utilized to produce acentric structures markedly different than their consti
105 e formation of a dicentric chromosome and an acentric, telomere-bearing, chromosome fragment in somat