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1 , and the number of incorporated sulfate and acetyl groups).
2 to assign unambiguously the position of the acetyl group.
3 ant hydroxylamine was then protected with an acetyl group.
4 ine are secondary amines with at least one N-acetyl group.
5 degradation through their N(alpha)-terminal acetyl group.
6 ghtly higher than that for the removal of an acetyl group.
7 stent ~3.1 degrees C decrease in Tm per 2'-O-acetyl group.
8 ction other than the biologically relevant N-acetyl group.
9 ay result from Ile-313 packing against the N-acetyl group.
10 omers due to intramolecular migration of the acetyl group.
11 (dG-C8-AAF) adducts that differ by a single acetyl group.
12 nitro, trifluoromethyl, fluoro, chloro, and acetyl groups.
13 tion, alpha1 and alpha2 contained N-terminal acetyl groups.
14 e labeled methyl and carbonyl carbons of the acetyl groups.
15 ey were substituted with from zero to four O-acetyl groups.
16 chiometrically substituted with up to four O-acetyl groups.
17 2 promotes p53 degradation by removing these acetyl groups.
18 and each mutant produced alginate lacking O-acetyl groups.
19 A PS were specific for epitopes involving O-acetyl groups.
20 hat have the capacity to modify core histone acetyl groups.
21 serotyped, and had marked reduction in GXM O-acetyl groups.
22 ient protocol for on resin deprotection of O-acetyl groups.
23 thylation may lead to the decomposition of O-acetyl groups.
24 esterase (NanS) to confirm the presence of O-acetyl groups.
25 bunit is on average substituted with three O-acetyl groups.
26 starch more hydrophobic by the insertion of acetyl groups.
27 ncluding variations such as N-glycolyl and O-acetyl groups.
28 hydrolyze long-chain fatty acyl groups over acetyl groups.
31 r in the cytoplasm, (ii) the export of the O-acetyl group across the cytoplasmic membrane, and (iii)
32 assembles the thiazole functionality from an acetyl group and l-cysteine via condensation, cyclizatio
33 imetry titration, indicating that both the N-acetyl group and sugar type may be essential for donor s
34 intramolecular hydrogen bonds between the N-acetyl group and the protein backbone are an important i
36 (HDACs) are a family of enzymes that remove acetyl groups and control the acetylation status of hist
38 ions between the degree of substitution with acetyl groups and properties of the modified preparation
40 al and biological processes, the role of the acetyl groups and the complexity of their migration has
41 n isolated native oligomers with 13C labeled acetyl groups and the extraction of orientational constr
42 cally, the STM was used to cleave individual acetyl groups and to form Au-S bonds by manipulating sin
43 ygen to the Pd center, (4) hydrolysis of the acetyl group, and (5) reductive elimination of Pd(0), wh
44 ungal genes encoding enzymes that metabolise acetyl groups, and with genes for other hydrolyases such
48 taining disaccharide thioglycoside with 6- O-acetyl group as donor building blocks for the alpha-dire
50 phosphates, (ii) the release of small excess acetyl groups as acetylcarnitine and ketone bodies, and
51 ation of the biaryl axis and the presence of acetyl groups as important structural elements for the b
58 O-acetylated ManNAc residues that contained acetyl groups at O-3, with some species acetylated at O-
59 indicate that GlcNAc residues on WTAs and O-acetyl groups at the 6-position of muramic acid residues
60 xylose has a hydroxyl group (instead of an N-acetyl group) at C2 and lacks the CH(2)OH group at C5; t
62 has also been established that PDC flux and acetyl group availability limits aerobic ATP re-synthesi
63 pyruvate dehydrogenase complex activation or acetyl group availability occurred during the first 20 s
64 urately predicting which proteins receive an acetyl group based on their protein sequence is expected
65 -acylthio substituent, the benzoyl group and acetyl groups being removed 50 and 5 times as fast as th
66 and catalyzes the reversible transfer of an acetyl group between the alpha-amino groups of ornithine
67 tor-binding site on beta4Gal-T1, while the N-acetyl group-binding pocket in beta4Gal-T1 adjusts to ma
68 sugar-acceptor binding site, a hydrophobic N-acetyl group-binding pocket is found, formed by residues
70 A that gets subsequently converted into a 3-acetyl group by 3-vinyl bacteriochlorophyllide a hydrata
71 deacetylase enzymes catalyze removal of the acetyl group by hydrolysis or by an NAD(+)-dependent rea
72 ides that results in the exchange of the 4-O-acetyl group by the glacial acetic acid that serves as e
73 OPV structures and can be converted to the S-acetyl group by treatment with sodium thiomethoxide and
74 lly active chromatin, whereas the removal of acetyl groups by histone deacetylases (HDACs) correlates
76 thin 3.9 A of five aromatic residues and its acetyl group close to residues C187/188 of the principle
79 ted, for the first time, the existence of an acetyl group deficit at the onset of contraction and has
84 east in part attributable to a limitation in acetyl group delivery/availability at the onset of exerc
89 these compounds are possible candidates for acetyl group-donors of 2AP, predominately in the form of
90 that develops on the carbonyl oxygen of the acetyl group during both the formation of the acyl-enzym
91 to encode acetyltransferases, which transfer acetyl groups either to internal lysine residues or to t
93 protease cathepsin L (CTSL) that remove the acetyl group first and then the unacetylated lysine grou
96 pecificity, we suggest that the bulky serine acetyl group forces a realignment of the omega end of th
98 the activated complex is the transfer of the acetyl group from acetyl CoA to the acceptor lysine resi
99 ic enzymes that catalyze the transfer of the acetyl group from acetyl coenzyme A (AcCoA) to the free
100 ric enzyme that catalyzes the transfer of an acetyl group from acetyl coenzyme A to polyamines such a
101 se gene product catalyzes the transfer of an acetyl group from acetyl coenzyme A to the C3 hydroxyl m
102 .3.1.8) catalyzes reversible transfer of the acetyl group from acetyl phosphate to coenzyme A (CoA),
103 .8) catalyzes the reversible transfer of the acetyl group from acetyl phosphate to coenzyme A (CoA),
104 .8) catalyzes the reversible transfer of the acetyl group from acetyl phosphate to coenzyme A (CoA):
106 that catalyze the reversible transfer of an acetyl group from acetyl-CoA to choline and L-carnitine,
107 se (EctA; EC 2.3.1.178), which transfers the acetyl group from acetyl-CoA to EctB-formed l-2,4-diamin
110 ferase (EaDAcT) catalyzes the transfer of an acetyl group from acetyl-CoA to the sn-3 position of dia
111 yme was shown to catalyse the transfer of an acetyl group from acetyl-CoA to the terminal nitrogen of
112 ve been shown to catalyze the transfer of an acetyl group from acetyl-coenzyme A (Ac-CoA) to the amin
113 nal helix, such as removal of the N-terminal acetyl group from AcTM1aZip or striated muscle alpha-TM,
114 tylase 6 (HDAC6) catalyzes the removal of an acetyl group from lysine residues of several non-histone
115 le to catalyse the reversible transfer of an acetyl group from N-acetylornithine to glutamate, but no
116 show that LsrF catalyzes the transfer of an acetyl group from P-HPD to coenzyme A yielding dihydroxy
117 fied two enzyme activities that transfer the acetyl group from platelet-activating factor (PAF) in a
118 e deacetylases catalyze the hydrolysis of an acetyl group from post-translationally modified acetyl-l
119 ent enzymes catalyze a reaction in which the acetyl group from substrate is transferred to the ADP-ri
120 ccurs first, followed by the transfer of the acetyl group from the donor substrate to the ADP-ribose
121 ent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is tran
122 cetylase (HDAC) catalyzes the removal of the acetyl group from the lysine residues in the N-terminal
123 6 (HDAC6) primarily catalyzes the removal of acetyl group from the side chain of acetylated lysine re
124 ent in membranes of F. novicida, removes the acetyl group from undecaprenyl phosphate-N-acetylgalacto
125 llular function by catalyzing the removal of acetyl groups from -N-acetylated lysine residues of vari
126 erologously expressed PMR5 protein transfers acetyl groups from [(14) C]-acetyl-CoA to oligogalacturo
128 transferase (SSAT) catalyzes the transfer of acetyl groups from acetylcoenzyme A to spermidine and sp
129 deacetylases (HDACs) catalyze hydrolysis of acetyl groups from acetyllysine side chains and are targ
130 (HDACs) are known to catalyze the removal of acetyl groups from both histones and non-histone protein
131 mily of enzymes that catalyze the removal of acetyl groups from core histones, resulting in a compact
133 r the enzyme is unknown, HerE hydrolyzes the acetyl groups from heroin to yield morphine and from phe
138 e of biological processes through removal of acetyl groups from histones as well as non-histone prote
142 They regulate gene expression by removing acetyl groups from lysine residues in histone tails, res
143 Cs) are enzymes that catalyze the removal of acetyl groups from lysine residues of histone and nonhis
145 atively regulate gene expression by removing acetyl groups from lysine residues present in histones a
146 nzymatic activity, preventing the removal of acetyl groups from lysine residues within histone tails.
148 eins (84% identity) that catalyze release of acetyl groups from modified N-terminal lysines of core h
149 ses that strip readily accessible methyl and acetyl groups from polymers like pectin and xylan, formi
150 Neisseria gonorrhoeae functions to release O-acetyl groups from the C-6 position of muramoyl residues
151 Gram-negative bacteria, the translocation of acetyl groups from the cytoplasm is performed by an inte
152 deacetylases (HDACs) catalyse the removal of acetyl groups from the N-terminal tails of histones.
153 harbors the activity that cleaves side chain acetyl groups from xylan-like substrates, and the bindin
155 tant strain that produced alginate lacking O-acetyl groups gave an amide II signal approximately five
158 tide deformylase for the N-formyl over the N-acetyl group has been studied with N-alpha-fluoroacetyl
160 MBPS-protein conjugate vaccines, in which N-acetyl groups have been replaced by propionyl groups (N-
161 hough the steady-state abundances of histone acetyl groups have been reported, the rate at which hist
163 and 1,250 cm(-1) (C---O stretching of the O-acetyl group in alginate), as compared to biofilms of no
165 bel from water to the carbonyl oxygen of the acetyl group in OAADPr is consistent with water addition
166 duction by p53 inactivates p53 by removal of acetyl group in p53 molecule, thus functioning as an aut
167 ed acyl migration-resistant analogs using an acetyl group in place of the free hydroxyl group in orde
168 were traced to the absence of the N-terminal acetyl group in rWT that participates in an H-bond to th
169 t of native N-acetyl groups with 13C-labeled acetyl groups in a simple disaccharide derivative, (GlcN
170 substituent groups: 1-phosphoglycerol and O-acetyl groups in EPS-1 and a single O-acetyl group in EP
171 The method relies on the replacement of acetyl groups in isolated native oligomers with 13C labe
172 cetyl-coenzyme A transporting and delivering acetyl groups in many essential biochemical processes, w
173 e, for the first time, that the migration of acetyl groups in oligosaccharides and polysaccharides ma
174 ffect, indicating the critical role of the N-acetyl groups in the stimulation of proinflammatory cyto
176 emonstrated directly that the absence of the acetyl group increases the susceptibility of succinoglyc
177 immunogenicity associated with removal of O-acetyl groups indicates that O acetylation is essential
183 tiply acetylated residues, but in which each acetyl group is isotopically labeled, permit studies of
186 and quantum chemical modeling, we show that acetyl group migration is a much more complex phenomenon
187 Nod-factors made by the nodL mutant lack an acetyl group; mutation of nodF causes the nitrogen (N)-l
189 ied enzyme catalyzed transacetylation of the acetyl group not only from PAF to lysoplasmalogen formin
190 rphyrin IX with strongly electron-polarizing acetyl groups not only leads to much lower meso-carbon r
191 proteins found in chromatin, by addition of acetyl groups occurs to a greater degree when the histon
192 s a ping-pong kinetic mechanism in which the acetyl group of acetyl-CoA is initially transferred to a
194 uggested significant interaction between the acetyl group of acetylcholine and the alphaY93 residue.
198 dditional hydrogen bond formed between the N-acetyl group of GalNAc moiety with the Tyr-289 side chai
200 de-N-acetylase capable of hydrolyzing the N-acetyl group of Lc(3)Cer was detected in bovine brain ex
202 n 199 serves to hydrogen bond with the C2' N-acetyl group of sugar D, thus preventing the formation o
203 hevamine, the carbonyl oxygen atom of the N-acetyl group of the -1 sugar residue has rotated away fr
208 iosynthesis, catalyzing the removal of the N-acetyl group of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylg
209 ng region displayed modes indicating that 3C-acetyl groups of BChl a are all involved in molecular in
212 ble for accommodating both the hydroxy and N-acetyl groups of the substrate during sugar ring rotatio
214 n-391 in UGT3A1 is able to accommodate the N-acetyl group on C2 of UDP-GlcNAc so that the anomeric ca
218 perties of the carbonyl moiety in the 17beta-acetyl group on the D-ring of the anesthetic steroids (3
219 ural occurrences of galactosamine lacking an acetyl group on the nitrogen, has been identified as a p
223 a feedforward circuit whereby HAT1 captures acetyl groups on nascent histones and drives H4 producti
225 deacetylases (HDACs) catalyze the removal of acetyl groups on the amino-terminal lysine residues of c
226 one acetylation by catalyzing the removal of acetyl groups on the NH(2)-terminal lysine residues of t
227 to further investigate the effect of 2'/3'-O-acetyl groups on the stability of RNA duplex structure,
228 etyl-CoA), and catalyses the transfer of the acetyl group onto a specific lysine residue (K238).
229 d the dynamic incorporation of (13)C-labeled acetyl groups onto specific histone lysines with quantit
230 ture, being different only in their relative acetyl group orientations, cis (gamma' approximately 180
231 de additional specific interactions of the N-acetyl group oxygen and nitrogen with Lys-343 and Asp-32
233 3)-enzymes that oppose Kac by buffering the acetyl group pool and catalyzing lysine deacetylation, r
235 -methyl groups, whereas abstraction from the acetyl group represents a minor pathway, in line with th
237 rom oxidation of the methyl group and the N6-acetyl group stems from the methyl group and the adjacen
238 rationalized by the greater capacity of the acetyl group than the benzoyl group to conjugate with th
240 urs in part through the direct deposition of acetyl groups that are derived from alcohol onto histone
243 Although G-AF and G-AAF differ by only an acetyl group, they exert different effects on DNA replic
244 uished only by the presence or absence of an acetyl group, they have profoundly different effects on
245 ch are metabolized into acetyl-coA, labeling acetyl groups through subsequent incorporation into prot
246 ic membrane, and (iii) the transfer of the O-acetyl group to a periplasmic protein or to alginate.
247 staglandin (PG) synthesis by transfer of its acetyl group to a serine residue in the cyclooxygenase (
252 the antibody (K(Ab)) on even addition of an acetyl group to P(1) of the peptide, the antibody fails
253 tif reveals that the tyrosine binds to the N-acetyl group to select for the "boat" conformation of N-
254 e carbonyl carbon of AcCoA, transferring the acetyl group to the acceptor peptide substrate (rate-lim
255 acyl carrier protein domain, transfer of the acetyl group to the acyl carrier protein domain is suppr
256 and undergo light-responsive addition of an acetyl group to the alpha-amino group of the amino-termi
259 wn to transfer an 18O label from the peptide acetyl group to the ribose 1'-position of OAADPr, provid
260 I) triggers metal-mediated hydrolysis of the acetyl groups to afford a large, rapid, and zinc-induced
262 cetylase (HDAC) proteins that add and remove acetyl groups to and from target lysine residues within
263 strategy employs "light" and "heavy" labeled acetyl groups to block both N-termini and lysine residue
264 groups to DNA cytosine bases, of methyl and acetyl groups to proteins (histones) around which DNA is
270 mine N-acetyltransferases (NATs) catalyze an acetyl group transfer from AcCoA to primary arylamines,
271 mine N-acetyltransferases (NATs) catalyze an acetyl group transfer from acetyl coenzyme A (AcCoA) to
272 d with the lipoyl domains and intramolecular acetyl group transfer in the mechanism of active-site co
274 des methyl group transfer, CO insertion, and acetyl group transfer, fitting to experimental traces re
277 stone acetyltransferases (HATs) catalyze the acetyl-group transfer from acetyl-CoA to the epsilon-ami
282 eavage of an amide bond, and transfer of the acetyl group ultimately to the 2'-ribose hydroxyl of ADP
284 TIPS-ethynyl group (via TIPS-acetylene), or acetyl group (via tributyl(1-ethoxyvinyl)tin, followed b
285 ersion of the trichloroacetyl group to the N-acetyl group was achieved under mild conditions, fully c
286 n acetate leaving group with or without an N-acetyl group, was cytotoxic and displayed significant in
289 d possessing one specific internal 2'- or 3'-acetyl group, were used as synthetic standards in a rece
290 ith mice also showed an essential role for O-acetyl groups, where serum bactericidal titers following
291 s stems from steric hindrance effects of the acetyl group which significantly diminish the adduct-bas
292 reased hydrophobicity associated with adding acetyl groups, while the specific effects are a conseque
295 alyzed exchange of the methyl protons of the acetyl group with solvent; exchange is dependent on the
296 binds in the S1 site, predominantly via the acetyl group with the oxygen and acetamide nitrogen hydr
297 ecies undergoes reductive elimination of the acetyl group with the simultaneous release of two, low p
298 ts thereof, one obtained by substituting the acetyl group with the sulfonic amino acid taurine (Tau-L
299 n presented involves replacement of native N-acetyl groups with 13C-labeled acetyl groups in a simple