ライフサイエンスコーパス: acetyl-coenzyme A

1 responsible for the binding of the cofactor acetyl coenzyme A.

2 ion of inhibitor competition with respect to acetyl coenzyme A.

3 r accumulation of citrate, the precursor for acetyl coenzyme A.

4 ylhydralazine and arylamine substrates using acetyl coenzyme A.

5 ropylbenzoate) to isobutyrate, pyruvate, and acetyl coenzyme A.

6 y generating two-carbon units in the form of acetyl-coenzyme A.

7 te dehydrogenase, which converts pyruvate to acetyl-coenzyme A.

8 raction of a proton from the methyl group of acetyl-coenzyme A.

9 D375 is the base removing the proton of acetyl-coenzyme A.

10 Homocitrate synthase (acetyl-coenzyme A: 2-ketoglutarate C-transferase; E.C. 2

11 Homocitrate synthase (acetyl-coenzyme A:2-ketoglutarate C-transferase; E.C. 2.

12 nce for the posttranslational control of the acetyl coenzyme A (Ac-CoA) synthetase (AcsA) enzyme of B

13 , and arylhydrazines by acetyl transfer from acetyl-coenzyme A (Ac-CoA) and are found in many organis

14 me A synthetase (Acs) activates acetate into acetyl-coenzyme A (Ac-CoA) in most cells.

15 ures of human Naa60 (hNaa60) in complex with Acetyl-Coenzyme A (Ac-CoA) or Coenzyme A (CoA).

16 atalyze the transfer of an acetyl group from acetyl-coenzyme A (Ac-CoA) to the amine of a wide range

17 as been proposed to comprise condensation of acetyl coenzyme A (AcCoA) and glutamate semi-aldehyde to

18 etic studies of NAT2 with two acetyl donors, acetyl coenzyme A (AcCoA) and p-nitrophenyl acetate (PNP

19 re of the yeast protein Hpa2 in complex with acetyl coenzyme A (AcCoA) at 2.4 A resolution and withou

20 zyme A-S-acetyltryptamine, demonstrates that acetyl coenzyme A (AcCoA) binding is accompanied by a la

21 of the yeast histone acetyltransferase Hat1-acetyl coenzyme A (AcCoA) complex at 2.3 A resolution.

22 e (2-AF) to 2-acetylaminofluorene (2-AAF) by acetyl coenzyme A (AcCoA) dependent N-acetylation, as ve

23 Acetyl coenzyme A (AcCoA) is the central biosynthetic pr

24 NATs) catalyze an acetyl group transfer from acetyl coenzyme A (AcCoA) to arylamines, hydrazines, and

25 talyze the transfer of the acetyl group from acetyl coenzyme A (AcCoA) to the free amino group of ary

26 Acetyl coenzyme A (AcCoA) was the preferred substrate, b

27 zyme that catalyzes pyruvate's conversion to acetyl coenzyme A (AcCoA), thereby connecting these two

28 ltransferase (AANAT) in a reaction requiring acetyl coenzyme A (AcCoA).

29 Bi-substrate kinetic analysis using acetyl-coenzyme A (AcCoA) and an H3 histone synthetic pe

30 complex with inositol hexaphosphate (InsP6), acetyl-coenzyme A (AcCoA) and/or substrate Resistance to

31 Acetyl-coenzyme A (AcCoA) is a major integrator of the n

32 thase (MtIPMS) catalyzes the condensation of acetyl-coenzyme A (AcCoA) with alpha-ketoisovalerate (al

33 te lysine residues by employing the cofactor acetyl-coenzyme A (AcCoA), thereby providing a dynamic c

34 autophagosome biogenesis via its metabolite, acetyl-coenzyme A (AcCoA).

35 D(+) and ferredoxin for glucose oxidation to acetyl coenzyme A (acetyl-CoA) and CO2, NADH for the red

36 lerate moiety of PHBV is the condensation of acetyl coenzyme A (acetyl-CoA) and propionyl-CoA to form

37 they instead resorb acetate, activate it to acetyl coenzyme A (acetyl-CoA) by means of the enzyme ac

38 ed regions of biotin carboxylase subunits of acetyl coenzyme A (acetyl-CoA) carboxylases.

39 of p-coumarate to p-hydroxybenzaldehyde and acetyl coenzyme A (acetyl-CoA) encoded by the couAB oper

40 thesis of the central metabolic intermediate acetyl coenzyme A (acetyl-CoA) from acetate or for gener

41 Acetyl coenzyme A (acetyl-CoA) generated from glucose an

42 Acetyl coenzyme A (acetyl-CoA) is a key metabolite at th

43 Assimilation of acetyl coenzyme A (acetyl-CoA) is an essential process i

44 Metabolic production of acetyl coenzyme A (acetyl-CoA) is linked to histone acet

45 ng of triglycerides, suggesting an increased acetyl coenzyme A (acetyl-CoA) load.

46 an alternative carbon source utilization for acetyl coenzyme A (acetyl-CoA) production and gluconeoge

47 ing differentiation in a manner dependent on acetyl coenzyme A (acetyl-CoA) production by the enzyme

48 Here we report that acetyl coenzyme A (acetyl-CoA) stimulates RNA polymerase

49 oneogenesis by suppressing the expression of acetyl coenzyme A (acetyl-CoA) synthetase (Acss), leadin

50 tylation in single-cell eukaryotes relies on acetyl coenzyme A (acetyl-CoA) synthetase enzymes that u

51 d by the induction of acs, the gene encoding acetyl coenzyme A (acetyl-CoA) synthetase, leading to up

52 6 synthesizes polyhydroxybutyrate (PHB) from acetyl coenzyme A (acetyl-CoA) through reactions catalyz

53 In this cycle, glyoxylate is condensed with acetyl coenzyme A (acetyl-CoA) to give malate, which und

54 c bacteria lack isocitrate lyase and convert acetyl coenzyme A (acetyl-CoA) to glyoxylate via a novel

55 I/II domain-containing enzyme that condenses acetyl coenzyme A (acetyl-CoA) with malonyl-acyl carrier

56 P-citrate lyase (ACLY) synthesizes cytosolic acetyl coenzyme A (acetyl-CoA), a fundamental cellular b

57 pair and is sensitive to the availability of acetyl coenzyme A (acetyl-CoA), we investigated a role f

58 inery needed to metabolize ethanolamine into acetyl coenzyme A (acetyl-CoA).

59 significantly reduced dependence on p300 and acetyl coenzyme A (acetyl-CoA).

60 300 and demonstrate that A-485 competes with acetyl coenzyme A (acetyl-CoA).

61 revisiae, enabling biosynthesis of cytosolic acetyl coenzyme A (acetyl-CoA, the two-carbon isoprenoid

62 assimilated via two reactions, conversion of acetyl-coenzyme A (acetyl coenzyme A [acetyl-CoA]) to py

63 nvolved in conversion of acetyl phosphate to acetyl-coenzyme A (acetyl-CoA) and posttranscriptionally

64 Coenzyme A (CoA) and acetyl-coenzyme A (acetyl-CoA) are ubiquitous cellular m

65 ion reaction of fatty acid biosynthesis with acetyl-coenzyme A (acetyl-CoA) as a primer, although the

66 is a period at the onset of contraction when acetyl-coenzyme A (acetyl-CoA) availability limits mitoc

67 The biosynthesis of acetyl-coenzyme A (acetyl-CoA) by acetyl-CoA synthetase

68 Acetate and the related metabolism of acetyl-coenzyme A (acetyl-CoA) confer numerous metabolic

69 Acetyl-coenzyme A (acetyl-CoA) formed within the plastid

70 zyme but can also catalyze the hydrolysis of acetyl-Coenzyme A (acetyl-CoA) in the absence of an aryl

71 e survival of Mycobacterium tuberculosis and acetyl-coenzyme A (acetyl-CoA) is an essential precursor

72 rved mitochondrial homeostasis by regulating acetyl-coenzyme A (acetyl-CoA) metabolism.

73 The metabolite acetyl-coenzyme A (acetyl-CoA) serves as an essential el

74 The effect of ethanol and acetate on acetyl-coenzyme A (acetyl-coA) synthetases, which conver

75 transfer of a carboxyl group from biotin to acetyl-coenzyme A (acetyl-CoA) to form malonyl-CoA.

76 e laboratories by coupling the production of acetyl-coenzyme A (acetyl-CoA) to the acetylation of 4-a

77 In the absence of other enzymes, it binds acetyl-coenzyme A (acetyl-CoA), and catalyses the transf

78 iminates interconversion between acetate and acetyl-coenzyme A (acetyl-CoA), led to elevated basal le

79 ch encodes SREBP-1) and Acacb (which encodes acetyl coenzyme A [acetyl-CoA] carboxylase 2 [ACC2], a c

80 reactions, conversion of acetyl-coenzyme A (acetyl coenzyme A [acetyl-CoA]) to pyruvate catalyzed by

81 glucose oxidation to fuel the production of acetyl coenzyme A, acetylation of histones and induction

82 to 3.1-fold) in expression were observed for acetyl-coenzyme A acetyltransferase (AtoB), a probable a

83 Acetyl coenzyme A (acteyl-CoA) carboxylase (ACC) is the

84 The results suggest that acetyl coenzyme A acts as a mixed V and K type activator

85 at maps to a promoter region shared with the acetyl coenzyme-A acyl-transferase-1 (ACAA1), was associ

86 translation of enzymes regulating long-chain acetyl-coenzyme A (Acyl-CoA) metabolism.

87 ptimized GAT variant in ternary complex with acetyl coenzyme A and a competitive inhibitor, 3-phospho

88 hat the best inhibitors are competitive with acetyl coenzyme A and an X-ray cocrystal structure revea

89 he formation of N-acetylglutamate (NAG) from acetyl coenzyme A and glutamate.

90 histone acetyltransferase 1 in complex with acetyl coenzyme A and histone H4 peptide.

91 ns possesses the enzymes required to convert acetyl coenzyme A and oxalacetate to alpha-ketoglutarate

92 leading to depletion of the energy substrate acetyl coenzyme A and the antioxidant glutathione.

93 hermautotrophicus PpcA was not influenced by acetyl coenzyme A and was about 50 times less sensitive

94 l-lysine biosynthesis in fungi by condensing acetyl-coenzyme A and 2-oxoglutarate to form 3R-homocitr

95 rtate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A and aspartate.

96 catalyzes the condensation of glyoxylate and acetyl-coenzyme A and hydrolysis of the intermediate to

97 , usually involve incubation of radiolabeled acetyl-coenzyme A and malonyl-acyl carrier protein (MACP

98 Concentrations of acetyl-coenzyme A and nicotinamide adenine dinucleotide

99 pendent biosynthetic reaction which produces acetyl-coenzyme A and oxaloacetate from citrate and coen

100 ority of isoleucine was instead derived from acetyl-coenzyme A and pyruvate, possibly via the citrama

101 Isothermal titration studies of acetyl-coenzyme A and tobramycin binding to mutant forms

102 of 280 mM for L-glutamine and 150 microM for acetyl-coenzyme A and with a k(cat) value of 200 min(-1)

103 The K(m) apparent values for ATP, acetyl-coenzyme A, and BCCP were estimated to be 60+/-14

104 not properly activate either oxaloacetate or acetyl-coenzyme A, and the condensation reaction is over

105 lyzes the acetylation of zwittermicin A with acetyl coenzyme A as a donor group, suggesting that ZmaR

106 rm UDP-N,N'-diacetylbacillosamine, utilizing acetyl-coenzyme A as the acetyl group donor.

107 relative concentrations of acetyl phosphate, acetyl coenzyme A, ATP, and GTP over the course of the e

108 The activities of two novel enzymes, acetyl-coenzyme A:benzylalcohol acetyltransferase (BEAT)

109 Mutagenesis of a putative acetyl coenzyme A binding site produced a TAF(II)250 pro

110 ed its enzyme kinetics, suggesting decreased acetyl coenzyme A binding.

111 H274 hydrogen bonds to the carbonyl of acetyl-coenzyme A but also forms the back wall of the ox

112 , and some bacteria, IPP is synthesized from acetyl coenzyme A by the mevalonate pathway.

113 lex stimulates the conversion of pyruvate to acetyl-coenzyme A by the pyruvate dehydrogenase complex.

114 eed in cellulo and could be used to identify acetyl coenzyme A carboxylase (ACC) in Pseudomonas aerug

115 reased AMP-activated protein kinase (AMPK)-->acetyl coenzyme A carboxylase (ACC) phosphorylation and

116 the low-density lipoprotein (LDL) receptor, acetyl coenzyme A carboxylase (ACC), and fatty acid synt

117 Escherichia coli acetyl coenzyme A carboxylase (ACC), the first enzyme of

118 tion in muscle by inhibiting the activity of acetyl coenzyme A carboxylase (ACC).

119 via its phosphorylation and inactivation of acetyl coenzyme A carboxylase (ACC).

120 tty acid biosynthesis in yeast; ACC1 encodes acetyl coenzyme A carboxylase (Acc1), and FAS1 encodes t

121 T cell-specific deletion of acetyl coenzyme A carboxylase 1 (ACC1), an enzyme that c

122 transport into mitochondria via deletion of acetyl coenzyme A carboxylase 2 (ACC2) does not cause ca

123 ranscription factor 1c, fatty acid synthase, acetyl coenzyme A carboxylase 2, and carnitine palmitoyl

124 or miR-204-5p which was predicted to inhibit acetyl coenzyme A carboxylase beta, a key fatty acid oxi

125 ceded by the accumulation of plastid-encoded acetyl Coenzyme A carboxylase D proteins accounting for

126 ary electrophoretic (CE) assay for measuring acetyl coenzyme A carboxylase holoenzyme (holo-ACC) acti

127 horylation of AMPK and its downstream target acetyl coenzyme A carboxylase in response to estradiol (

128 atory element binding protein 1c), and ACACA(acetyl coenzyme A carboxylase) was not different between

129 , sterol regulatory element-binding protein, acetyl coenzyme A carboxylase, and fatty acid synthase.

130 naling to AMPK substrates, including Raptor, acetyl coenzyme A carboxylase, and PGC-1alpha, is attenu

131 protein of the biotin-dependent carboxylase, acetyl coenzyme A carboxylase.

132 nthesis, acting primarily on the activity of acetyl coenzyme A carboxylase.

133 phate-activated protein kinase activation of acetyl-coenzyme A carboxylase (ACC) and increased lipid

134 Acetyl-coenzyme A carboxylase (ACC) catalyzes the first

135 protein contents of fatty acid synthase and acetyl-coenzyme A carboxylase (ACC), reduced ACC phospho

136 in part by phosphorylating and inactivating acetyl-coenzyme A carboxylase (ACC), the rate-limiting e

137 on of AMPK and its downstream target phospho-acetyl-coenzyme A carboxylase (ACC).

138 arboxyl carrier protein isoform 2 (BCCP2) in acetyl-coenzyme A carboxylase (ACCase) function and fatt

139 ns of commercial rates (375 g ha(-1)) of the acetyl-coenzyme A carboxylase (ACCase) inhibiting herbic

140 Bacterial acetyl-coenzyme A carboxylase (ACCase) is a multicompone

141 Acetyl-coenzyme A carboxylase (ACCase) is a promising ta

142 Acetyl-coenzyme A carboxylase (ACCase) occurs in at leas

143 ase subunit of the heteromeric chloroplastic acetyl-coenzyme A carboxylase (ACCase) of Arabidopsis th

144 d nuclear gene (ACC2) that targets homomeric acetyl-coenzyme A carboxylase (ACCase) to plastids.

145 carrier protein 2 (BCCP2) inhibited plastid acetyl-coenzyme A carboxylase (ACCase), resulting in alt

146 ls are not sufficient to support heteromeric acetyl-coenzyme A carboxylase activity at a level that i

147 a1 and alpha2 AMPK activity are elevated and acetyl-coenzyme A carboxylase activity is decreased in t

148 CA inhibitors did not affect acetyl-coenzyme A carboxylase activity or total storage

149 downstream targets including phosphorylated acetyl-coenzyme A carboxylase and carnitine palmitoyltra

150 erodimer with the biotin acceptor protein of acetyl-coenzyme A carboxylase and catalyzes posttranslat

151 hosphorylation of downstream target of AMPK, acetyl-coenzyme A carboxylase and inhibition of p70S6 ki

152 ic carbon inside plastids for utilization by acetyl-coenzyme A carboxylase and the fatty acid synthes

153 The heteromeric acetyl-coenzyme A carboxylase catalyzes the first and co

154 l in natural environments, where heteromeric acetyl-coenzyme A carboxylase encoded in part by the chl

155 Plastidial acetyl-coenzyme A carboxylase from most plants is a mult

156 med for the L-type pyruvate kinase, S14, and acetyl-coenzyme A carboxylase genes.

157 S Ser633 was able to compete with Ser1177 or acetyl-coenzyme A carboxylase Ser79 for AMPKalpha phosph

158 plicated nuclear gene that targets homomeric acetyl-coenzyme A carboxylase to plastids, where the mul

159 carboxyl-carrier subunit of the heteromeric acetyl-coenzyme A carboxylase was isolated and sequenced

160 Saccharomyces cerevisiae ACC1 gene (encoding acetyl-coenzyme A carboxylase), which has three Gal4 bin

161 well as increased Ser(92) phosphorylation of acetyl-coenzyme A carboxylase, a downstream target of AM

162 tations in ACC2, encoding a plastid-targeted acetyl-coenzyme A carboxylase, cause hypersensitivity to

163 sphorylation of the AMPK substrates, p53 and acetyl-coenzyme A carboxylase, changes that correlated w

164 ased phosphorylation of both AMPK-Thr172 and acetyl-coenzyme A carboxylase-Ser79, a downstream enzyme

165 NDI-010976, an allosteric inhibitor of acetyl-coenzyme A carboxylases (ACC) ACC1 and ACC2, redu

166 Acetyl-coenzyme A carboxylases (ACCs) are required for t

167 Acetyl-coenzyme A carboxylases (ACCs) have crucial roles

168 Acetate, a precursor of acetyl coenzyme A (CoA) (a product of fatty acid beta-ox

169 nobiotics and/or endogenous substrates using acetyl coenzyme A (CoA) as a cofactor.

170 aretil (OG) is a small molecule inhibitor of acetyl coenzyme A (CoA) carboxylase (ACC), the enzyme th

171 A multisubunit form of acetyl coenzyme A (CoA) carboxylase (ACCase) from soybea

172 protein kinase (AMPK) levels, and diminished acetyl coenzyme A (CoA) carboxylase phosphorylation than

173 CO dehydrogenase/acetyl coenzyme A (CoA) synthase and pyruvate oxidoreduc

174 t this phenotype is due to altered fluxes of acetyl coenzyme A (CoA), a major intermediate in C(1), C

175 Acetyl coenzyme A (CoA), malonyl-CoA, adenosine triphosp

176 Pharmaceutical inhibition of acetyl-coenzyme A (CoA) carboxylase (ACC), a key fatty a

177 Plastidic acetyl-coenzyme A (CoA) carboxylase (ACCase) catalyzes t

178 ntrast, haloxyfop, an inhibitor of cytosolic acetyl-coenzyme A (CoA) carboxylase, inhibited only elon

179 , which in turn is decarboxylated to produce acetyl-coenzyme A (CoA) for various biosynthetic purpose

180 ling redirected metabolic fluxes to generate acetyl-Coenzyme A (CoA) from glucose resulting in augmen

181 e epigenome of MLL-rearranged AML by linking acetyl-coenzyme A (CoA) homeostasis to Bromodomain and E

182 erase catalyzes the reversible conversion of acetyl-coenzyme A (CoA) into acetylcarnitine.

183 Acetyl-coenzyme A (CoA) is used in the cytosol of plant

184 raction of both the cellular glycine and the acetyl-coenzyme A (CoA) needed for SAM synthesis.

185 Acetyl-coenzyme A (CoA) synthetase (Acs) is an enzyme ce

186 utant that has a disruption in the plastidic acetyl-coenzyme A (CoA) synthetase (ACS; At5g36880) gene

187 se (AcuC), which may control the activity of acetyl-coenzyme A (CoA) synthetase (AMP-forming, AcsA) i

188 f a member of this adenylate-forming family, acetyl-coenzyme A (CoA) synthetase, was determined in co

189 efective in a pathway involved in converting acetyl-coenzyme A (CoA) to glyoxylate (the ethylmalonyl-

190 at YopJ acted as an acetyltransferase, using acetyl-coenzyme A (CoA) to modify the critical serine an

191 rase (Pta) that converts acetyl-phosphate to acetyl-coenzyme A (CoA), led to the inhibition of RpoS a

192 lace in mitochondria to generate glycine and acetyl-coenzyme A (CoA), with glycine facilitating one-c

193 one of two cytosolic enzymes that synthesize acetyl-coenzyme A (CoA).

194 ovides at least 90% of precursors of plastid acetyl-coenzyme A (CoA).

195 n, a process that requires the generation of acetyl-coenzyme A (CoA).

196 hat mediates extensive interactions with the acetyl-coenzyme A cofactor, and structurally divergent N

197 The structure of the SSAT-spermine-acetyl-coenzyme A complex suggested that Tyr140 acts as

198 gest that sugar mobilization from glucose to acetyl-coenzyme A [corrected] is a collaboration between

199 -2, Idd3 candidate gene, CTLA-4, NRAMP1, and acetyl-coenzyme A dehydrogenase, long-chain (ACADL) (can

200 ays for acetyltransferase activity with [14C]acetyl coenzyme A demonstrated that ZmaR catalyzes the a

201 tion of the response regulator CpxR and (ii) acetyl coenzyme A-dependent acetylation of the alpha sub

202 orms of methionine, which MddA detoxifies by acetyl coenzyme A-dependent acetylation.

203 on from nucleosomal templates in vitro in an acetyl coenzyme A-dependent fashion.

204 n by the VP16 acidic activation domain in an acetyl coenzyme A-dependent manner.

205 Furthermore, we demonstrate that STAGA has acetyl coenzyme A-dependent transcriptional coactivator

206 ation is catalysed by the receptor-modifying acetyl coenzyme-A-dependent O-acetyltransferase encoded

207 rough two separable mechanisms: dampening of acetyl-coenzyme A-dependent carbon metabolism through hi

208 e complex (PDHc), which converts pyruvate to acetyl coenzyme A, enables E. coli to resist these antim

209 rom the A-cluster, but it did inhibit the CO/acetyl-coenzyme A exchange activity, probably by causing

210 The bisubstrate analogue, N1-spermine-acetyl-coenzyme A, exhibited linear, competitive inhibit

211 metabolism; this limits the availability of acetyl coenzyme A for histone acetylation at genes encod

212 d nitrogen sources for protein synthesis and acetyl-coenzyme A for cytosol-localized fatty acid elong

213 glutamine-derived citrate provides both the acetyl-coenzyme A for lipid synthesis and the four-carbo

214 lutamine-derived carbon produces citrate and acetyl-coenzyme A for lipid synthesis, which is required

215 ribosome binding sites for both the upstream acetyl coenzyme A formation and fatty acid synthase modu

216 was re-cast into three modules: the upstream acetyl coenzyme A formation module; the intermediary ace

217 hetase-1 (AceCS1) catalyzes the synthesis of acetyl coenzyme A from acetate and coenzyme A and is tho

218 tricarboxylic acid (TCA) cycle by producing acetyl coenzyme A from pyruvate.

219 diates arises due to the formation of [1-13C]acetyl coenzyme A from the labeled pyruvate, formed via

220 -coenzyme A, a sulfur-less, ketone analog of acetyl-coenzyme A, in its ternary complex with oxaloacet

221 ompanied by increased (14) C-glucose-derived acetyl-coenzyme A incorporation into sterols for fecal e

222 atalyzed by an apparent alpha(4)beta(4)-type acetyl coenzyme A-independent pyruvate carboxylase (PYC)

223 he transcriptional activity of p300 requires acetyl coenzyme A, indicating that it functions as a his

224 Acetyl coenzyme A inhibited the autokinase activity of P

225 o-gene operon responsible for the acetate<-->acetyl coenzyme A interconversion.

226 on, and it encodes enzymes for conversion of acetyl coenzyme A into butanol and butyrate.

227 roduced by PDH can be used for conversion of acetyl coenzyme A into reduced fermentation products, li

228 ivity of pyruvate dehydrogenase, which feeds acetyl-coenzyme A into the FAS II pathway.

229 Acetyl coenzyme A is an activator, and GarA, a forkhead

230 A steady state kinetic study showed that acetyl-coenzyme A is as efficient an ACPS substrate as c

231 We further show that glutamine-derived acetyl-coenzyme A is used for histone acetylation, where

232 histone acetylation, whereas glucose-derived acetyl-coenzyme A is used to acetylate amino sugars.

233 nsistent with this hypothesis, intracellular acetyl coenzyme A levels rose during growth in the prese

234 tion of N-acetylglutamate from glutamate and acetyl-coenzyme A, nor (detectably) the hydrolysis of N-

235 ary proton transfer from the methyl group of acetyl-coenzyme A only poorly, a process which occurs in

236 ructures of PglD in the presence of citrate, acetyl coenzyme A, or the UDP-4-amino-sugar were solved.

237 ays, such as the Calvin cycle, the reductive acetyl coenzyme A pathway, and the 3-hydroxypropionate c

238 eristics and in vivo rescue potential of the acetyl-Coenzyme A precursor S-acetyl-4'-phosphopantethei

239 Tricarboxylic acid acetyl coenzyme A production and ATP production were red

240 suggest that PDH is involved in most or all acetyl coenzyme A production in B. subtilis under anaero

241 The shift away from acetyl coenzyme A production toward carbon influx via an

242 nzyme activity, contributed significantly to acetyl-coenzyme A production.

243 30 microm for its substrates glyoxylate and acetyl coenzyme A, respectively, and was inhibited by br

244 is directly dependent on metabolites such as acetyl-coenzyme A, S-adenosylmethionine, and NAD+, among

245 NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system, thus l

246 The acetyl coenzyme A synthase (ACS) enzyme plays a central

247 kA) genes while downregulating expression of acetyl coenzyme A synthase (acs).

248 he proposed organonickel intermediate in the acetyl coenzyme A synthase catalytic cycle.

249 In vivo expression of CO dehydrogenase/acetyl coenzyme A synthase in Methanosarcina spp. is coo

250 a protein-based model for the NiP center of acetyl coenzyme A synthase using a nickel-substituted az

251 ial redox (hydrogenases and CO dehydrogenase/acetyl coenzyme A synthase), they have never been associ

252 a genetics-based method is used to truncate acetyl-coenzyme A synthase from Clostridium thermoacetic

253 is activity of the isolated alpha subunit of acetyl-coenzyme A synthase/carbon monoxide dehydrogenase

254 educe CO2 to acetate via the Wood-Ljungdahl (acetyl coenzyme A synthesis) pathway.

255 nsgenic hearts, despite similar fractions of acetyl-coenzyme A synthesis from palmitate and oxygen us

256 yruvate dehydrogenase complex contributed to acetyl-coenzyme A synthesis from pyruvate, and their act

257 ranscription into the adjacent gene encoding acetyl coenzyme A synthetase (acs), is overlapping and d

258 AcuA controls the activity of acetyl coenzyme A synthetase (AcsA; EC 6.2.1.1) in this

259 sible for the acetylation of the AMP-forming acetyl coenzyme A synthetase (SacAcsA, SACE_2375).

260 ation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2.

261 in p-cymene catabolism; and cymE encodes an acetyl coenzyme A synthetase whose role in this pathway

262 The reaction was catalyzed by the action of acetyl coenzyme A synthetase, inorganic pyrophosphatase,

263 Acetyl coenzyme A synthetase-1 (AceCS1) catalyzes the sy

264 Acetyl-coenzyme A synthetase (Acs) activates acetate int

265 Acetyl-coenzyme A synthetase (ACS) belongs to the family

266 ole of lysine acylation in metabolism is the acetyl-coenzyme A synthetase (Acs) enzyme.

267 te Salmonella enterica, the metabolic enzyme acetyl-coenzyme A synthetase (Acs) is regulated by a Sir

268 the activity of the central metabolic enzyme acetyl-coenzyme A synthetase (Acs).

269 Acetyl-coenzyme A synthetase catalyzes the two-step synt

270 Although many Archaea have AMP-Acs (acetyl-coenzyme A synthetase) and ADP-Acs, the extant me

271 acs encodes acetyl-coenzyme A synthetase, a high-affinity enzyme tha

272 , encoding alpha-amylase, and acsA, encoding acetyl-coenzyme A synthetase, and normal activation of a

273 termined that csrA positively regulates acs (acetyl-coenzyme A synthetase; Acs) expression and isocit

274 SUR-5 also has some sequence similarity to acetyl coenzyme A synthetases and is predicted to contai

275 of unknown function; PrpE showed homology to acetyl coenzyme A synthetases.

276 ase steps along with the ultimate product of acetyl-coenzyme A that can be further oxidized for ATP s

277 he TCA cycle for the generation of cytosolic acetyl-coenzyme A that can be used for fatty acid and ch

278 ate formate lyase cannot convert pyruvate to acetyl coenzyme A, the required precursor for acetate an

279 nase, which is involved in the conversion of acetyl coenzyme A to acetate, is induced when cells are

280 ndently of the TCA cycle, direct cleavage of acetyl coenzyme A to CO and 5,10-methyl tetrahydrofuran

281 ethylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate.

282 on the mevalonate pathway for conversion of acetyl coenzyme A to isopentenyl diphosphate.

283 CC1), an enzyme that catalyzes conversion of acetyl coenzyme A to malonyl coenzyme A, a carbon donor

284 talyzes the transfer of an acetyl group from acetyl coenzyme A to polyamines such as spermidine and s

285 talyzes the transfer of an acetyl group from acetyl coenzyme A to the C3 hydroxyl moiety of several t

286 stead, LDHA maintains high concentrations of acetyl-coenzyme A to enhance histone acetylation and tra

287 oreductase responsible for the conversion of acetyl-coenzyme A to ethanol during fermentative growth.

288 Inspired by acetyl-coenzyme A transporting and delivering acetyl gro

289 sm pathways suggested that a perturbation of acetyl coenzyme A turnover was the cause of decreased Ph

290 oxidation of CO to CO2 and the synthesis of acetyl-coenzyme A, utilizing two novel Ni-Fe-S active si

291 dance with the high carbon efficiency drive, acetyl-coenzyme A was entirely produced using the carbon

292 tography and mass spectrometry verified that acetyl-coenzyme A was the product of the reaction.

293 onents for their mission: E1 and E2 generate acetyl-coenzyme A, whereas the FAD/NAD(+)-dependent E3 p

294 conversion of indole-3-pyruvate to indole-3-acetyl-coenzyme A, which is a potential precursor of IAA

295 2, 53 +/- 2, and 84 +/- 7%, respectively, of acetyl-coenzyme A while the rate of anaplerotic substrat

296 generation of the enol(ate) intermediate of acetyl-coenzyme A, while main-chain hydrogen bonds and b

297 minant enzyme catalyzing the condensation of acetyl coenzyme A with malonyl-ACP in P. aeruginosa.

298 FO), which decarboxylates pyruvate and forms acetyl-coenzyme A with concomitant reduction of low-pote

299 ed two independent production mechanisms for acetyl-coenzyme A with different biological functions.

300 to catalyze the condensation of pyruvate and acetyl coenzyme A, with the formation of (R)-citramalate