ライフサイエンスコーパス: acetylate

1 racts with the p300 acetyltransferase and is acetylated.

2 which is in the RRM RNA binding domain, was acetylated.

3 f the mature effector was found likely to be acetylated.

4 en three and six repeating units and to be O-acetylated.

5 The presence of a 3alpha-OH was crucial: 3-acetylated, 3-deoxy, and 3-oxo analogs of 3alpha5alpha-P

6 rotected 3-deoxy-3-fluorogalactopyranose and acetylated 4-deoxy-4-fluorogalactopyranose.

7 ne (deacetylated/D) and N-acetylglucosamine (acetylated/A) units.

8 port fibril structures of three N-terminally acetylated (Ac) alpha-syn constructs, Ac1-140, Ac1-122,

9 Here, we show that APE1 is acetylated (AcAPE1) after binding to the AP sites in chr

10 SIRT3 expression and simultaneously reduced acetylated ACO2.

11 ue, and identified it as a complex of lysine-acetylated actin (KAc-actin) and cyclase-associated prot

12 ase-associated protein (CAP) bound to lysine-acetylated actin (KAc-actin) is required for INF2 inhibi

13 study reveals that a complex between lysine-acetylated actin and cyclase-associated protein inhibits

14 The NSL complex is also able to acetylate additional histone H4 sites.

15 sociated Factor 1 (TAF1) associates with K43 acetylated AE and this association plays a pivotal role

16 e treatment of control mitochondria with the acetylating agent acetic anhydride inhibits pyruvate upt

17 third fraction containing trisaccharides was acetylated allowing the purification of the main trisacc

18 2 double-knockout podocytes showed dispersed acetylated alpha-tubulin and rare protrusions.

19 fferentiation was demonstrated via increased acetylated alpha-tubulin and SOX9 proteins, the number o

20 ted in the formation of discontinuous, short acetylated alpha-tubulin fragments, and the decrease of

21 haS in humans is constitutively N-terminally acetylated (alphaSacetyl), although the impact of this m

22 zymatic synthetic strategies for preparing N-acetylated analogues of O-acetylated NmW CPS oligosaccha

23 when a beta-amylase treatment was applied to acetylated and debranched potato starch.

24 relation between the total protein amount of acetylated and detyrosinated MT.

25 S-associated loci on elements differentially acetylated and directly regulating differentially expres

26 In Loxl3-/- mice, Stat3 is constitutively acetylated and naive CD4(+) T cells are potentiated in T

27 ing, does not appear to discriminate between acetylated and non-acetylated lysine 16, modification st

28 reconstructions of pure samples of alphaTAT1-acetylated and SIRT2-deacetylated microtubules to visual

29 Moreover, MAP7 binds to the acetylated and stable region of individual microtubules

30 y, previous studies reported the presence of acetylated and succinylated anthocyanins in corn kernels

31 are detyrosinated in epithelial cells, while acetylated and tyrosinated microtubules comprise the maj

32 Using mutations that mimic the acetylated and unacetylated forms of the protein, we sho

33 y examining the N-terminal sequences of many acetylated and unacetylated proteins and more recently b

34 osomal proteins are known to be N-terminally acetylated, and the acetyltransferases responsible for t

35 umor xenografts that STAT3 is constitutively acetylated as a result of ALK activity.

36 singly, these NEDD8 trimers are additionally acetylated, as shown by mass spectrometry analysis, and

37 lcpNAc-(1 -> 5)-alpha-KDOp-(2 -> partially O-acetylated at 3-hydroxyl of GlcNAc.

38 lowing for the Asf1-H3K14ac/H4 complex to be acetylated at H3K56 by Rtt109-Vps75.

39 isruption the NL-associated TADs become more acetylated at histone H3 and less compact, while backgro

40 Here, we show that NAT1 is acetylated at K(100) and K(188) and that changes in prot

41 H3 acetylated at K14 (H3K14ac) facilitates the processivity

42 s of histone H3 and of the BRD domain for H3 acetylated at Lys(14) (H3K14ac), the exact mode of H3 bi

43 -mediated association to histone H3 peptides acetylated at lysine 14 (H3K14Ac), validating the import

44 BRD3 binds to histone H3 acetylated at lysine 18 (H3K18ac) in vitro and co-occupi

45 PHF5A, a component of U2 snRNPs, can be acetylated at lysine 29 in response to multiple cellular

46 In this study, we discovered that FUS was acetylated at lysine-315/316 (K315/K316) and lysine-510

47 osyl residues and the mannosyl residues were acetylated at O-2 and O-3.

48 -alpha-1-(PO(4)-] repeating units that are O-acetylated at O-6 of the GlcNAc.

49 due to a deletion in wciG Serotype 35C was O-acetylated at the 5- and 6-positions of 3-beta-galactofu

50 lpha-1,4-N-acetylgalactosaminouronic acid, O-acetylated at the C-3 position, resistant to the commonl

51 As acetylated beta-catenin promotes mesodermal rather than

52 )-inhibited acidic polymer built of randomly acetylated beta-linked tetrasaccharide repeats.

53 d the binding to different putative ligands (acetylated BSA [AcBSA], zymosan, mannan, and LPS from Es

54 transferases used in this work, and two were acetylated but not deacetylated by sirtuin.

55 cteria, hundreds of proteins are known to be acetylated, but the biological significance of the major

56 RRM2 is directly acetylated by KAT7, and deacetylated by Sirt2, respectiv

57 med to be the Vi monomer both de-O- and de-N-acetylated by mono- and bidimensional Nuclear Magnetic R

58 aken together, this study shows that NAT1 is acetylated by p300/CBP in situ and is deacetylated by th

59 We found PARN is primarily acetylated by the acetyltransferase p300 at Lys-566 and

60 Here, we present evidence that FAAP20 is acetylated by the acetyltransferase p300/CBP on lysine 1

61 CobB long isoform (CobB(L)) is N-terminally acetylated by the YiaC protein of this bacterium.

62 ysine (de)acetylation control, four were not acetylated by two acetyltransferases used in this work,

63 o acetylation assays showed that CobB(L) was acetylated by YiaC; liquid chromatography-tandem mass sp

64 portantly, we show that aspirin can directly acetylate cGAS and efficiently inhibit cGAS-mediated imm

65 Partially acetylated chitosan oligosaccharides (paCOS), consisting

66 dress this hypothesis, we prepared partially acetylated chitosan oligosaccharides from a chitosan pol

67 i-bromodomain proteins, such as BRD4, highly acetylated chromatin forms a new phase-separated state w

68 ding of BRD2 to H4Ac protects the underlying acetylated chromatin from attack by histone deacetylases

69 the paralogous CBP, induces a dynamic hyper-acetylated chromatin state and promotes the formation of

70 ctional transcriptional regulators that bind acetylated chromatin via their conserved tandem bromodom

71 s and binding of its bromodomains to DNA and acetylated chromatin, respectively, and BRD4S phosphoryl

72 molog 2 A (DIP2A) is known to be involved in acetylated coenzyme A (Ac-CoA) synthesis and is primaril

73 Access to hatJ and its acetylated congener hatK permitted their biological eval

74 in was critical for maintaining the level of acetylated cortactin.

75 s such as myristoylated lysine compared with acetylated counterparts, but the deacetylase activity ca

76 Here we show that acetylated COX-2 also retains COX activity, forming pred

77 Residual cyclooxygenase activity of aspirin-acetylated COX-2 forms 15 R-prostaglandins that inhibit

78 Although the K(m) of arachidonic acid for acetylated COX-2 was ~3-fold lower than for uninhibited

79 Acetylated COX-2, in contrast, gains a new catalytic act

80 Treatment with N-AS increases acetylated COX2 and N-AS-triggered SPMs in microglia of

81 ates serine 565 (S565) of COX2, and the N-AS-acetylated COX2 induces the production of specialized pr

82 -alpha-(1 -> 4)-d-galactosamines and their N-acetylated derivatives allowed the first precise analysi

83 Moreover, the acetylated derivatives were also detected but at lower f

84 ntained the greatest relative abundance of O-acetylated derivatives, Binocrit expressed the least Neu

85 red for the first time together with their N-acetylated derivatives.

86 low amylose rice starches, whether native or acetylated, did not form films with desirable characteri

87 Acetylated eEF1A1 (Ac-eEF1A1) translocates into the nucl

88 show that the lysine acetyltransferase Tip60 acetylates eEF1A1, whereas the histone deacetylase HDAC2

89 lacking H3.3 demonstrate reduced capacity to acetylate enhancers that are activated upon differentiat

90 re enrichment ( P=0.001) than differentially acetylated enhancers ( P=0.8) and super-enhancers ( P=0.

91 catalytic efficiency for PG formation by the acetylated enzyme was reduced 10-fold due to a concomita

92 The O-acetylating enzyme in Gram-positive bacteria, O-acetyltr

93 rases CREB-binding protein and p300 both can acetylate ERK1/2.

94 Acetylated ERK1 exhibits reduced enzymatic activity towa

95 Here we show that, when acetylated, eukaryotic elongation factor 1A1 (eEF1A1) ne

96 we observed elevated levels of CIDEC and its acetylated form in HDAC-deficient adipocytes as well as

97 copy to probe the nature of the N-terminally acetylated form of alphaS (NTAc-alphaS) bound to synapti

98 Furthermore, vIL-6-induced acetylated form of STAT3 interacted with DNMT1 to form a

99 lavonol derivatives, mainly glycosylated and acetylated forms of quercetin (22.64 mg/100 g dw) and ka

100 We also found that acetylated FOXO3 preferentially bound JNK1, and a mutant

101 l of various transcription factors, and when acetylated, Foxp3 is stabilized and transcriptionally ac

102 for HDAC8-catalyzed deacetylation of singly-acetylated, full-length protein substrates, revealing th

103 Lastly, CREB-binding protein/p300 acetylated FUS, whereas both sirtuins and histone deacet

104 t to actin, and we propose that this complex acetylates G-actin before it is incorporated into filame

105 was detected during SG resolution, and K376-acetylated G3BP1 was seen outside SGs.

106 In this context, we have tailored an acetylated galactoglucomannan (AcGGM) fibre to match uni

107 , an l-histidine methyl ester linker, and an acetylated galactose bonded to one of the aromatic nitro

108 in which the glucosamine moieties are either acetylated (GlcNAc) or modified as a free amine (GlcNH(2

109 action was anthocyanin compounds, especially acetylated>diglucosylated forms than glucosylated ones.

110 Intriguingly, the accumulation of lysine 5-acetylated H2B was cell age-dependent and was associated

111 ccumulation of the epigenetic mark, lysine 5-acetylated H2B.

112 termine that non-canonical histone signature acetylated H3 lysine 23 (H3K23ac)-binding protein tripar

113 Our proposed mechanism suggests that Gcn5 acetylates H3K14, recruiting remodeler complexes, allowi

114 ssociated with the ASS1 promoter to maintain acetylated H3K14ac and H3K27ac for ASS1 silencing.

115 We show that pre-acetylated H3K14ac/H4 functions with Asf1 to drive speci

116 ere associated with an active enhancer mark, acetylated H3K27.

117 e (q=+8) is essentially a random coil, hyper-acetylated H4 (q=+3) is virtually as compact and stable

118 the levels of nascent chromatin-associated, acetylated H4 in wild-type and hdac2 cells.

119 Conformational ensembles of acetylated H4 match the corresponding K->X substitutions

120 al modification (PTM) reader that recognizes acetylated H4.

121 AT8 that recognizes the methylated H3K36 and acetylated H4K16.

122 fork degradation in BRCA-deficient cells by acetylating H4K8 at stalled replication forks, which rec

123 tionally, purified YfmK was able to directly acetylate HBsu in vitro, suggesting that it is the secon

124 trated that two of these, YfmK and YdgE, can acetylate Hbsu, and their potential sites of action on H

125 s, the secondary amides of peptides and of N-acetylated hexose sugars.

126 of p300/CBP-associated factor (PCAF), which acetylates HIF-1alpha, blocked PGE(2)-mediated increases

127 The films from acetylated high amylose starches had higher moisture con

128 yltransferase (HAT) p300 and its paralog CBP acetylate histone lysine side chains and play critical r

129 acetylation of key histone lysine residues (acetylated histone 3 lysine 27 and histone 3 lysine 18)

130 ncing of dimethylated histone 3 lysine 4 and acetylated histone 3 lysine 27 as well as transposase-ac

131 -methylated histone 3 lysine 4 (H3K4me3) and acetylated histone 3 lysine 9 (H3K9ac) at the HER2 promo

132 rized chromatin reader cassette to bind hypo-acetylated histone 4 tails at promoters, guaranteeing co

133 mpetition that exists among the "readers" of acetylated histone and nonhistone proteins and provide a

134 The expression of histone H3 (H3), acetylated histone H3 (AC-H3), histone deacetylase 1 (HD

135 Here, we show that acetylated histone H3 (AcH3), base J and a kinetochore f

136 ucleosome arrays consisting of homogeneously acetylated histone H3 (H3K18 and H3K27) and measured the

137 rified the increased enrichment of lysine-27 acetylated histone H3 at discrete loci, accompanied by e

138 deprivation causes intragenic enrichment of acetylated histone H3 at lysines 9 (H3K9ac) and 56 (H3K5

139 Chromatin immunoprecipitation of acetylated histone H3 on the promoters of plant-responsi

140 In this study, we found that K27-acetylated histone H3 specifically recruited Super Elong

141 etion, there was an increased association of acetylated histone H3 with the SET and MYND-domain conta

142 the conserved YEATS domain, which recognizes acetylated histone H3.

143 t than racAR-42 in promoting accumulation of acetylated histone H4 in MM96L melanoma cells.

144 T) proteins, which are epigenetic readers of acetylated histone lysine tail residues.

145 enabled CBP to bind with higher affinity to acetylated histone peptides, indicating a potential epig

146 iated BAF factor), which involves reading of acetylated histone tails by the bromodomain-containing p

147 1 alters the direct association of BRD4 with acetylated histone-packaged promoters and reduces the tr

148 tes the transcriptional activity of LEF1 and acetylates histone H3 lysine 56 in the promoters of Wnt

149 (hMOF), a member of the MYST family of HATs, acetylates histone H4 at lysine 16 (H4K16ac).

150 em in Drosophila, regulates gene activity by acetylating histone H4 preferentially at lysine 16.

151 gulator that localizes to DNA via binding to acetylated histones and controls the expression of thera

152 of BRD4, a bromodomain protein that binds to acetylated histones and is a key transcriptional coactiv

153 BRD4 is a BET family protein that binds acetylated histones and regulates transcription.

154 anscription, which correlated with increased acetylated histones H3K9 and H3K14 (H3K9/14Ac).

155 BET) proteins, BRD2, BRD3, BRD4 and BRDT, to acetylated histones preventing recruitment of RNA polyme

156 the interaction between its YEATS domain and acetylated histones reduces the ATAC complex-dependent p

157 main family are epigenetic readers that bind acetylated histones through their bromodomains to regula

158 BRD7 simultaneously binds to acetylated histones to promote Smad-chromatin associatio

159 the present study, we use a series of singly acetylated histones to test the hypothesis that histone

160 bate and BETi blocked the binding of BRD4 to acetylated histones.

161 Acetylated HMGB1 (Ac-HMGB1) secreted by geminin-overexpr

162 ins encoding acetyltransferases can directly acetylate host proteins to alter immunity.

163 including the histone acetyltransferase p300 acetylated in its activation loop, which could explain s

164 generating modelled structures of proteins N-acetylated in mouse liver, we show that proximity to a n

165 E2F1 is acetylated in response to DNA damage but the role this p

166 Here we show that SIRT3 is reversibly acetylated in the mitochondria and unexpectedly is a tar

167 considered that long-lived microtubules are acetylated inside their lumen and that microtubule acety

168 ing in the induction of P300 which, in turn, acetylates IRS1/2, inhibits its association with the ins

169 e activity was negatively affected when YiaC acetylated its N terminus.

170 ng DNA damage, the bromodomain of BRD9 binds acetylated K515 on RAD54 and facilitates RAD54's interac

171 f the protein, we show that the inability to acetylate key HBsu lysine residues results in a more com

172 Acetylated Klf5 is also essential for basal progenitors'

173 cell proliferation and differentiation, and acetylated KLF5 is known to alter epithelial proliferati

174 , with basal cells preferentially expressing acetylated Klf5.

175 Structural studies on N-acetylated KRAS-GDP lacking the iMet revealed the presen

176 Chitosans, beta-1,4-linked partially N-acetylated linear polyglucosamines, are very versatile a

177 In response to virus infection, the acetylated Lys129 is removed by SIRT1, which promptly in

178 GCN5 was previously shown to acetylate lysine 14 of histone 3 (H3K14ac) in the promot

179 bitors mimic the interactions of the natural acetylated lysine (KAc) histone substrate through key in

180 r to discriminate between acetylated and non-acetylated lysine 16, modification states of the histone

181 tivity as marked by histone 3 containing the acetylated lysine 27 (H3K27ac).

182 nalysis of DNA methylation, histone marking (acetylated lysine 9 in histone H3 and trimethylated lysi

183 elative changes in the abundance of specific acetylated lysine peptides measured in DKO versus Sirt3

184 moval of acetyl group from the side chain of acetylated lysine residues in cytoplasmic proteins such

185 d BD2) that are necessary for recognition of acetylated lysine residues in the N-terminal regions of

186 Recent studies indicate that acetylated lysine residues mainly exhibit low acetylatio

187 ate transcription by selectively recognizing acetylated lysine residues on chromatin.

188 Bromodomains bind to acetylated lysine residues on histone tails and thereby

189 enetic reader proteins that bind to specific acetylated lysine residues on histone tails where they f

190 main (BRD), a protein module that recognizes acetylated lysine residues on histones and other protein

191 G/APE1 on compact chromatin, suggesting that acetylated lysine residues on the H3 tail domain play di

192 proteins that acts as the primary reader for acetylated lysine residues.

193 Our focus is on bromodomains, which bind to acetylated lysine residues.

194 es 18 enzymes that catalyze deacetylation of acetylated lysine residues; however, the specificity and

195 isrupt function by preventing recognition of acetylated lysine substrates.

196 ed lysine-to-glutamine (KQ) mutants to mimic acetylated lysines and screened 15 KQ mutants.

197 ns are epigenetic readers that interact with acetylated lysines of histone tails.

198 JQ1, which blocks the functional readout of acetylated lysines, reduced heroin self-administration a

199 RiCE17 removing 2-O-acetylations from double acetylated mannose.

200 idue in an oligosaccharide, including double acetylated mannoses, while the RiCE2 is active on 3-O-,

201 Notably, the highly acetylated/methylated K18-I150V variant was less soluble

202 However, acetylated microtubules are predominantly bundled, and b

203 on also resulted in reduced levels of apical acetylated microtubules, and rescue experiments with the

204 HDAC6 inhibition increases acetylated Miro1 in axons, and acetyl-mimetic Miro1 K105

205 immunohistochemistry for SIRT3 activity via acetylated MnSOD(K68) Murine AEC SIRT3 and cleaved caspa

206 AANAT1 acetylates monoamines and inactivates them, and we found

207 In alkaline protein microenvironments, per-O-acetylated monosaccharides undergo base-promoted beta-el

208 in centriole number and the accumulation of acetylated MTs.

209 cally unlocks the nutritive potential of 9-O-acetylated mucus sialic acids for foraging by bacteria t

210 his work also provide first evidence of de-N-acetylated muropeptides from P. aeruginosa The method de

211 ng and combination analyses, we uncover that acetylating mutp53(R158G) could render cancers susceptib

212 In vivo, NatB was seen to preferentially acetylate N termini starting with the initiator Met foll

213 tion of phosphoramidate chemistry to 1,3,4-O-acetylated N-acetylmannosamine (Ac(3)ManNAc) to deliver

214 glycosylation using a metabolic label, tetra-acetylated N-azidoacetylgalactosamine (Ac4GalNAz).

215 We discover 20 sulfated and 4 acetylated N-glycans on IgGs.

216 he Golgi apparatus, and has a preference for acetylating N termini of the transmembrane proteins.

217 Recombinant p300 directly acetylated NAT1 in vitro.

218 Our data suggest that trimeric, acetylated NEDD8 attenuates PARP-1 activation after oxid

219 HAT1 is an essential gene in mammals that acetylates newly synthesized histone H4 and is involved

220 rate of protein turnover (t (1/2)) of non-Nt-acetylated Nmnats did not significantly differ from thos

221 id not significantly differ from those of Nt-acetylated Nmnats.

222 es for preparing N-acetylated analogues of O-acetylated NmW CPS oligosaccharides which can serve as s

223 validated by titration of 10-80% mixture of acetylated/nonacetylated alpha-tubulin peptides in the b

224 s on the HDAC1 containing CoREST complex and acetylated nucleosome substrates which revealed a notabl

225 RD, Sin3B, MiDAC and SMRT with site-specific acetylated nucleosome substrates.

226 SMAD2 can bind pre-acetylated nucleosome-depleted sites.

227 Acetylated oligosaccharides are common in nature.

228 ted into chromatin during DNA replication is acetylated on lysines 5 and 12.

229 SaAcuA can acetylate or propionylate SaAcs reducing its activity by

230 pped the locations of nucleosomes containing acetylated or methylated lysines in the histone tails of

231 tuin-1 and Foxo3alpha with downregulation of acetylated p53 expression and prevented downregulation o

232 mulation of Foxo3alpha and downregulation of acetylated p53 expression.

233 mmunoblotting for levels of RNF128, p53, and acetylated p53.

234 teraction after overexpression of CBP, which acetylates p53, or with an acetylation mimicking carboxy

235 the formation of robust and mature MurNAc O-acetylated peptidoglycan and infer its role in the divis

236 spB mutant with improved hydrolysis of fully acetylated PNAG oligosaccharides correlates with improve

237 spB has increased catalytic activity on de-N-acetylated PNAG oligosaccharides, but the molecular basi

238 inal epithelial cells secrete high levels of acetylated polyamines into the prostatic lumen, sensitiz

239 N1-acetyltransferase (SSAT) activity, which acetylates polyamines leading to their secretion and dri

240 ans, a family of B-(1,4)-linked, partially N-acetylated polyglucosamines, are considered to be among

241 Herein we report that the matrikine acetylated Pro-Gly-Pro (PGP) stimulates vascular inflamm

242 The structure elucidation of the acetylated product made it possible to identify gentiano

243 dipate and tryptophan, to their respective N-acetylated products in several plant species.

244 s spectrometry analysis showed that CBP/p300 acetylates prostacyclin synthase, which regulates Treg d

245 Acetylated proteins are involved in numerous cellular pr

246 tudying protein acetylation is to get purely acetylated proteins at specific positions.

247 responsible for removing acetyl groups from acetylated proteins.

248 MAP7 also binds to the acetylated region of microtubules to prevent depolymeriz

249 eractions persist and contacts between newly acetylated regions are formed after inhibiting RNA polym

250 conformation datasets to link differentially acetylated regions with their cognate genes and identify

251 ng different interfaces the higher abundance acetylated residues are proximal to the regulatory sites

252 he acetylome, relatively few of the specific acetylated residues have been matched to a proposed KDAC

253 s(326) and Lys(328) are among the documented acetylated residues.

254 More importantly, Gcn5 directly acetylates Rph1 in vitro and in vivo, and Gcn5-containin

255 N-AS then acetylates serine 565 (S565) of COX2, and the N-AS-acety

256 1 employ glycan-based receptors carrying 9-O-acetylated sialic acid (9-O-Ac-Sia).

257 O-Acetylated sialic acid has been found in the Neisseria m

258 rimer in isolation and in complex with a 9-O-acetylated sialic acid.

259 2) as receptors, whereas the others employ O-acetylated-sialic acid (a key feature of metallopeptidas

260 All three viruses attach to 9-O-acetylated sialoglycans via spike protein S with hemaggl

261 pends on a novel acetyltransferase domain to acetylate signalling proteins from plant and animal host

262 totic factors FoxO1/3 are overly degraded by acetylated Skp2, resulting in polyploid cell division, g

263 Acetylated SOD2 promotes hypoxic signaling via increased

264 encoded by S. aureus USA300 and E. faecalis acetylate spermidine, spermine and norspermidine, that s

265 gated the EMT and oncogenesis induced by the acetylated SPZ1-TWIST1 complex.

266 Using the synthetic unmodified and acetylated stable isotope labeled peptides DKTIGGG and D

267 The insoluble complexes from the acetylated starch displayed the V-type pattern, whereas,

268 The acetylated starch-based films had a lower decomposition

269 Acetylated starches films exhibited more rapid degradati

270 r DNA repair and maintaining RECQL4 in a low acetylated state.

271 nformational ensembles of the unmodified and acetylated states by using the experimental cryo-EM dens

272 Both enzymes were active on acetylated substrates, although each showed a higher fer

273 le (and, potentially, glucuronic acid, any-N-acetylated sugar, or ribitol).

274 aining monosaccharides, phosphorylated and N-acetylated sugars, polyols, carboxylic acids, nucleotide

275 ines and amides, primary amides, and novel N-acetylated sugars, which together account for nearly 50%

276 ylation" between protein cysteines and per-O-acetylated sugars.

277 Acetylated TAF9 does not bind to the PU.1 gene promoter

278 We show that DPF2 interacts with the acetylated tails of both histones 3 and 4 via bipartite

279 Acetylated tau, in particular, has recently been implica

280 derstood, Esco1 and Esco2 acetyltransferases acetylate the cohesin subunit Smc3, thereby inducing sta

281 ated N-acetyltransferase (bGNAT) superfamily acetylate the epsilon amino group of an active site lysi

282 ulting NuA4/TIP60 multi-subunit complexes to acetylate the histone H4 tail in chromatin.

283 plexes (NatA-NatC), which co-translationally acetylate the N-termini of eukaryotic proteins.

284 In vitro, AtaT2 acetylates the aminoacyl moiety of isoaccepting glycyl t

285 NatE co-translationally acetylates the N-terminus of half the proteome to mediat

286 gae T3SE HopZ1a is an acetyltransferase that acetylates the pseudokinase AtZED1 and triggers recognit

287 an cycle, the lysine acetyltransferase TIP60 acetylates the transcriptional activator BMAL1 leading t

288 quired for the conjugation and inhibition of acetylated thermolysin, which lacks primary amines.

289 tions revealed that at low pH, the N (alpha)-acetylated Thr-2 makes direct and frequent "bind-and-rel

290 mponents of the plant cell wall and they are acetylated to be protected from degradation by glycoside

291 In MB cells GD3 is largely acetylated to GD3(A).

292 We identified an enzyme that acetylates triacylinositols, a function homologous to th

293 iary morphology accompanied by alteration of acetylated tubulin and IFT88 expression.

294 8 overexpression correlated to a decrease of acetylated tubulin induced by tau overexpression in N2a

295 While ATP depletion led to cell death, over-acetylated tubulin led to inhibition of motility and mit

296 th the use of antibodies specific for cilia (acetylated tubulin, gamma-tubulin, polycystin [PC] 1, PC

297 logical activity and the distribution of the acetylated units (P(A): pattern of acetylation) has been

298 Per-O-acetylated unnatural monosaccharides containing a bioort

299 of the interactions between Ubc9 and its K65 acetylated variant (Ac-Ubc9K65) with three NDSMs derived

300 native tetrameric PKM2 is phosphorylated or acetylated, which initiates a switch to a dimeric/monome