ライフサイエンスコーパス: acetylmuramic acid

1 peptidoglycan (PG) at the C-6 position on N-acetylmuramic acid.

2 ccurrence of N-glycolylmuramic rather than N-acetylmuramic acid.

3 -links by cleaving the peptide moiety from N-acetylmuramic acid.

4 roup to activate the carboxyl group of UDP-N-acetylmuramic acid.

5 ic for the bacterial cell wall amino sugar N-acetylmuramic acid.

6 ciate with the repeating disaccharide beta-N-acetylmuramic acid, (1-->4)-beta-N-acetylglucosamine of

7 The N-acetylmuramic acid alpha-1-phosphate (MurNAc-alpha1-P) u

8 al septum-specific PGTase in vivo using an N-acetylmuramic acid analogue incorporation assay.

9 Peptidoglycan is made of repeating N-acetylmuramic acid and N-acetylglucosamine disaccharides

10 ating disaccharide unit of beta-1,4-linked N-acetylmuramic acid and N-acetylglucosamine.

11 oglycan; group B carbohydrate is linked to N-acetylmuramic acid, and capsular polysaccharide is linke

12 Here we show that the 1,6-anhydro-N-acetylmuramic acid (anhMurNAc) is returned to the biosyn

13 med AmiD, as a possible second 1,6-anhydro-N-acetylmuramic acid (anhMurNAc)-l-alanine amidase in Esch

14 enzyme, the Pseudomonas aeruginosa anhydro-N-acetylmuramic acid (anhNAM) kinase (AnmK).

15 ed disaccharide of N-acetylglucosamine and N-acetylmuramic acid appended with a highly conserved stem

16 066 and SL1067 were required for growth on N-acetylmuramic acid as a sole carbon source.

17 formed by linear glycan chains composed of N-acetylmuramic acid-(beta-1,4)-N-acetylglucosamine (MurNA

18 oding the endospore-specific peptidoglycan-N-acetylmuramic acid deacetylase) serves as a contingency

19 s also retain more diaminopimelic acid and N-acetylmuramic acid during germination than wild-type spo

20 se of naked glycans containing 1,6-anhydro N-acetylmuramic acid ends.

21 ide, N-acetylglucosaminyl-beta-1,4-anhydro-N-acetylmuramic acid (GlcNAc-anhMurNAc).

22 The M. smegmatis mutant is devoid of UDP-N-acetylmuramic acid hydroxylase activity and synthesizes

23 e gene namH encoding the mycobacterial UDP-N-acetylmuramic acid hydroxylase by computer data base sea

24 ed a novel assay for the mycobacterial UDP-N-acetylmuramic acid hydroxylation reaction and demonstrat

25 nd between N-acetylglucosamine and anhydro-N-acetylmuramic acid in cell wall degradation products fol

26 by acetylation of the C6 hydroxyl group of N-acetylmuramic acid in the PG glycan backbone.

27 al C3 enolpyruvyl substrate, to UDP-methyl-N-acetylmuramic acid in the presence of NADPH.

28 peptidoglycan recycling enzyme 1,6-anhydro-N-acetylmuramic acid kinase (AnmK) from Pseudomonas aerugi

29 on to the structurally related 1,6-anhydro-N-acetylmuramic acid kinase (AnmK), it forms markedly fewe

30 e sugar is first phosphorylated by anhydro-N-acetylmuramic acid kinase (AnmK), yielding MurNAc-P, and

31 determinant of the pneumococcal autolysin (N-acetylmuramic acid-L-alanine amidase).

32 UDP-N-acetylmuramic acid:L-alanine ligase (MurC) catalyzes the

33 hermore, E. coli also recycles the anhydro-N-acetylmuramic acid moiety by first converting it into N-

34 composed of peptides linked to the sugars N-acetylmuramic acid (MurNAc) and GlcNAc.

35 s the beta-1,4 glycosidic linkages between N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (Glc

36 polymer, consisting of a linear, repeating N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (Glc

37 lyze the B-1,4-glycosidic bonds connecting N-acetylmuramic acid (MurNAc) and N-acetylglucosamine (Glc

38 main peptidoglycan N-deacetylase acting on N-acetylmuramic acid (MurNAc) residues and conferring lyso

39 ternating N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc) units, cross-linked via pept

40 units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (MurNAc), which are cross-linked by s

41 nscription by binding the PG precursor UDP-N-acetylmuramic acid (MurNAc)-pentapeptide.

42 etylglucosamine (GlcNAc) B-(1-4)-linked to N-acetylmuramic acid (MurNAc).

43 The muramyl residue is present as N-acetylmuramic acid, N-glycolylmuramic acid, and muramic

44 ase of SpA by removing amino sugars [i.e., N-acetylmuramic acid-N-acetylglucosamine (MurNAc-GlcNAc)]

45 s the cleavage of glycosidic bonds between N-acetylmuramic acid (NAM) and N-acetylglucosamine residue

46 alternating N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) cross-linked by short peptide s

47 ing units of N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM) with an appended peptide.

48 e repeats of N-acetylglucosamine (NAG) and N-acetylmuramic acid (NAM).

49 scopy analysis of short pulses with either N-acetylmuramic acid or D-alanine metabolic probes showed

50 up of un-cross-linked peptides attached to N-acetylmuramic acid partially substituting the function o

51 on the detection of the cell precursor UDP-N-acetylmuramic acid pentapeptide intermediate terminating

52 empedopeptin is undecaprenyl pyrophosphate-N-acetylmuramic acid(pentapeptide)-N-acetylglucosamine (li

53 of the soluble peptidoglycan precursor UDP-N-acetylmuramic acid-pentapeptide (UDP-MurNAc-pentapeptide

54 of the murein precursor, Lipid I, from UDP-N-acetylmuramic acid-pentapeptide and the lipid carrier, u

55 timate soluble peptidoglycan precursor UDP-N-acetylmuramic acid-pentapeptide in the cytoplasm.

56 MurQ is an N-acetylmuramic acid-phosphate (MurNAc-P) etherase that co

57 onversion of the 2,3-dideuterio-UDP-methyl-N-acetylmuramic acid product to 2,3-dideuterio-2-hydroxybu

58 s removal of a peptide side chain from the N-acetylmuramic acid residue by a cwlD-encoded muramoyl-L-

59 ions of Asn46 and Asp52 with the D-subsite N-acetylmuramic acid residue help to distort that pyranose

60 ees of polymerization and terminating with N-acetylmuramic acid residues at the reducing ends.

61 he deep end of a long binding groove, with N-acetylmuramic acid situated in the middle of the groove,

62 nd human clinical strains, did not require N-acetylmuramic acid supplementation for growth as pure cu

63 e dehydrogenase operon, genes required for N-acetylmuramic acid synthesis, a 14-gene gas vesicle clus

64 peptide is amide-linked to the carboxyl of N-acetylmuramic acid, thereby tethering the COOH-terminal

65 as an enzyme activity that can convert UDP-N-acetylmuramic acid to UDP-N-glycolylmuramic acid.

66 samine deacetylase (Pgd) and acetylated by O-acetylmuramic acid transferase (Oat).

67 residues are ligated to uridine diphospho-N-acetylmuramic acid (UDP-MurNAc).

68 zae MurC in complex with its substrate UDP-N-acetylmuramic acid (UNAM) and Mg(2+) and of a fully asse

69 e of a 40-fold excess of uridine diphospho N-acetylmuramic acid (UNAM) either aerobically or anaerobi

70 endent ligation of L-alanine (Ala) and UDP-N-acetylmuramic acid (UNAM) to form UDP-N-acetylmuramyl-L-

71 xists in a tightly locked complex with UDP-N-acetylmuramic acid (UNAM), the product of the MurB react

72 Modification of N-acetylmuramic acid with wall teichoic acid, a ribitol-ph

73 ide units (N-acetylglucosamine-[beta-1, 4]-N-acetylmuramic acid) with different degrees of polymeriza