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1 nsferase activity of MOF, a H4K16ac-specific acetyltransferase.
2 which is generated at DSBs by the Tip60/KAT5 acetyltransferase.
3 pendently of Smc3p's regulation by the Eco1p acetyltransferase.
4 cant impact on the activities of arylamine N-acetyltransferase.
5 all domains of life that is carried out by N-acetyltransferases.
6 an important feedback mechanism to regulate acetyltransferases.
7 nit by members of the Eco1 family of cohesin acetyltransferases.
8 into the virulence activity of YopJ class of acetyltransferases.
10 thelial growth factor, we identified histone acetyltransferase 1 (HAT1) as an induced gene that enhan
14 Two different isoforms of this protein, N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NA
19 f Arabidopsis (Arabidopsis thaliana) xylan O-acetyltransferase 1 (XOAT1), a member of the plant-speci
20 There is growing evidence that arylamine N-acetyltransferase 1 has an important cellular role in ad
21 the coactivator complexes SAGA (Spt-Ada-Gcn5-acetyltransferase)(1,2) and transcription factor IID (TF
25 eotide polymorphism in the human arylamine N-acetyltransferase 2 (Nat2) gene has recently been identi
26 protein, N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2), are expressed in human hepat
27 leus in human cell lines and binds to lysine acetyltransferase 2A (KAT2A, also known as GCN5) in the
29 es and of overcoming the rare aminoglycoside acetyltransferase (3)-IV class of aminoglycoside-modifyi
36 tylating enzyme in Gram-positive bacteria, O-acetyltransferase A (OatA), is a two-domain protein cons
38 After overexpression of arylalkylamine N-acetyltransferase (AANAT; the enzyme regulating melatoni
39 s insufficiently understood, Esco1 and Esco2 acetyltransferases acetylate the cohesin subunit Smc3, t
43 4 fusions resulted in loss of histone lysine acetyltransferase activity in a dominant-negative fashio
44 sing a dominant negative p300 mutant lacking acetyltransferase activity in mouse muscle attenuated LL
45 study reveals an important role for tubulin acetyltransferase activity in presynaptic maintenance, w
47 or of LLC tumor-induced muscle wasting whose acetyltransferase activity may be targeted for therapeut
49 y in a set of genomic targets depends on the acetyltransferase activity of MOF, a H4K16ac-specific ac
50 emonstrate the essentiality of the polyamine acetyltransferase activity of SAT1 for its function as a
51 ion of RUVBL1 is critically required for the acetyltransferase activity of TIP60, promoting histone H
53 posttranslational modifications impact TIP60 acetyltransferase activity to influence the outcome of D
55 elucidated the regulatory mechanisms of p300 acetyltransferase activity, but it is not known whether
56 additional amino acid residues important for acetyltransferase activity, we isolated and characterize
57 nditions, PKM2 is a target of OGA-associated acetyltransferase activity, which facilitates O-GlcNAcyl
69 in this cluster that potentially encode an O-acetyltransferase, an N-acetylglucosamine transferase, a
70 to identify inhibitors targeting aspartate N-acetyltransferase (ANAT), a promising target for the tre
71 x structure with those of 14-3-3:serotonin N-acetyltransferase and 14-3-3:heat shock protein beta-6 c
72 SRP2BP, a coactivator for CRP2, is a histone acetyltransferase and a driver of smooth muscle gene exp
73 identified an essential role for the histone acetyltransferase and deubiquitinase SAGA complex in per
74 ive MORF complex as a histone H3K23-specific acetyltransferase and elucidate its mechanism of action.
76 purified AtNAA50 displays N(alpha)-terminal acetyltransferase and lysine-epsilon-autoacetyltransfera
77 sis of garsubellin A, an enhancer of choline acetyltransferase and member of the large family of poly
79 ce staining using antibodies against choline-acetyltransferase and neurofilament was performed to dif
80 w small molecule induced recruitment of P300 acetyltransferase and the acetylation of H3K27 at precis
81 ur work illustrates a causal role of histone acetyltransferases and acetylation in senescence and sug
83 controlled by the opposing action of histone acetyltransferases and histone deacetylases (HDACs).
84 bromodomains of the p300/KAT3B and CBP/KAT3A acetyltransferases and that this interaction is required
85 g protein (CBP) and p300 are closely related acetyltransferases and transcriptional coactivators.
86 se line with deficiencies in CrAT (carnitine acetyltransferase) and Sirt3 (sirtuin 3)-enzymes that op
87 pentanoate-originated acetyl-CoA for histone acetyltransferases, and by pentanoate-triggered enhancem
88 f microtubule stabilizers, including tubulin acetyltransferases; and (3) genetic epistasis suggests t
89 activating mutations of the CREBBP and EP300 acetyltransferases are among the most common genetic alt
90 es, and the biochemical functions of these O-acetyltransferases are evolutionarily conserved througho
91 rising that the targets of bacterial protein acetyltransferases are very diverse, making their bioche
92 d mass spectrometry, we identified the EP300 acetyltransferase as uniquely associated with BRD4 throu
93 F1 encodes a protein modifier of two histone acetyltransferases associated with ID: KAT6A (also known
94 in C.elegans, we show that the alpha-tubulin acetyltransferase ATAT-2 and the signaling hub RPM-1 are
96 abidopsis and konjac is mediated by mannan O-acetyltransferases belonging to the Domain of Unknown Fu
97 ns belonging to the bacterial GCN5-related N-acetyltransferase (bGNAT) superfamily acetylate the epsi
98 eads to a specific activation of the histone acetyltransferase Brd2, which results in histone H3K27 a
99 on of TH with nitric oxide synthase, choline acetyltransferase, calbindin, calretinin, and serotonin,
100 own that pathogen effector proteins encoding acetyltransferases can directly acetylate host proteins
101 tically, DEX-bound GR recruits histone H3K27 acetyltransferase CBP to promote activation of C/EBPbeta
102 mutants is rescued by depleting the histone acetyltransferase CBP-1/p300 or the transcription factor
104 ansferases MLL3/MLL4 (KMT2C/KMT2D) and H3K27 acetyltransferases CBP/p300 to recruit Brd4 to enhancers
106 cortex contains neurons that express choline acetyltransferase (ChAT) and are a potential local sourc
107 immunohistochemical visualization of choline acetyltransferase (ChAT) and the low-affinity neurotroph
108 ridization to localize mRNA encoding choline acetyltransferase (ChAT) and vesicular acetylcholine tra
109 ally ubiquitinated proteins, reduced choline acetyltransferase (ChAT) enzyme expression, fragmented m
111 iny neurons (MSNs) and D2-expressing choline acetyltransferase (ChAT) interneurons express Slc6a15, w
112 lutamic acid decarboxylase (GAD) and choline acetyltransferase (ChAT) revealed that all CG neurons ar
113 ported to potentiate the activity of choline acetyltransferase (ChAT), the enzyme that produces the n
116 able to glaucomatous damage, whereas choline acetyltransferase (ChAT)-positive and glycinergic AC sub
119 veal how transcriptional regulators, histone acetyltransferases, chromatin remodelers, and transcript
120 e) cells lacking the N-terminal (Nt) protein acetyltransferase complex NatB exhibit an approximate 50
121 ead, functions as an ATP-independent histone acetyltransferase complex similar to the yeast NuA4, tar
123 rsions of the SAGA complex and another large acetyltransferase complex, ATAC (Ada2A containing acetyl
127 Gcn5 is part of the large SAGA (Spt-Ada-Gcn5 acetyltransferase) complex and a smaller ADA acetyltrans
128 A) and Esa1-Yng2-Epl1 (Piccolo NuA4) histone acetyltransferase complexes have the capacity to crotony
129 Gcn5 acetyltransferase functions in multiple acetyltransferase complexes in yeast and metazoans.
130 nd humans, nucleosome remodeling and histone acetyltransferase complexes originate from gene duplicat
134 y creating mice lacking the enzyme carnitine acetyltransferase (CrAT) in the proximal tubules, thus l
136 of epigenetic inhibitors, we found that the acetyltransferase CREBBP/EP300 is a major regulator of c
138 lphaH) and 10-deacetylbaccatin III-10-beta-O-acetyltransferase (DBAT) have been identified in this fu
140 in response to increases in temperature, and acetyltransferase-deficient archaeal strains exhibit tem
142 was dependent on bacterial dihydrolipoamide acetyltransferase (DlaT), a major protein expressed on t
143 otransferase(2'')-Ia possesses an N-terminal acetyltransferase domain and a C-terminal phosphotransfe
144 rget with small-molecule inhibitors, but the acetyltransferase domain and the bromodomain in GCN5 mig
145 mass spectrometry, we identified the histone acetyltransferase domain of HBO1 as being essential in t
146 Fos eRNAs directly interact with the histone acetyltransferase domain of the enhancer-linked transcri
147 the role of missense mutations in the lysine acetyltransferase domain that are more frequently observ
148 ly of bacterial effectors depends on a novel acetyltransferase domain to acetylate signalling protein
150 ytes and uncovered that ETS1 and the histone acetyltransferase E1A-binding protein P300 (EP300 or p30
152 thesis is catalyzed by l-2,4-diaminobutyrate acetyltransferase (EctA; EC 2.3.1.178), which transfers
153 gh-throughput screens against an amino-sugar acetyltransferase enzyme, PglD, involved in biosynthesis
155 nhancers together with SMAD3 and the histone acetyltransferase EP300, enabling transcription of TGF-b
156 gh induction of nuclear translocation of the acetyltransferase EP300, which increases histone H3K27 a
158 arrangements of the ZNF384 gene with histone acetyltransferases EP300 and CREBBP ZNF384-rearranged AL
162 rase activity, we isolated and characterized acetyltransferases from other acetyl-TAG-producing plant
165 that mice lacking enzymatic activity of the acetyltransferase GCN5 ((Gcn5(hat/hat) )), which were pr
166 Here we demonstrate a novel role of the acetyltransferase GCN5 in a previously undescribed mecha
169 eletion of the previously implicated histone acetyltransferase Gcn5, but G1/S cell cycle regulated tr
170 onditional knockout mice for the key histone acetyltransferase Gcn5, which resulted in abnormal chrom
171 mr5) carries a mutation in a putative pectin acetyltransferase gene that confers enhanced resistance
172 hemophilic red alga with the chloramphenicol acetyltransferase gene, rendering this organism insensit
173 spartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A a
174 tes of injury, paralleling increased histone acetyltransferase general transcription factor IIIC subu
175 was recently reported, but the presence of O-acetyltransferase genes in the serotype 35C cps locus su
176 ions in the regulation of BCL6, including in acetyltransferase genes, occur in clinically aggressive
177 coccal serotype 33A has two membrane-bound O-acetyltransferase genes, wciG and wcjE A 33A wcjE-defici
178 ical evidence that glucosamine 6-phosphate N-acetyltransferase (Gna1), a key enzyme in this pathway,
179 regulator with intrinsic kinase and histone acetyltransferase (HAT) activities that activates transc
180 n5 and sirtuins are highly conserved histone acetyltransferase (HAT) and histone deacetylase (HDAC) e
182 Notch-binding region of MAML1 to the histone acetyltransferase (HAT) domain of p300 rescues expressio
186 ng Tra1 module, the core module, the histone acetyltransferase (HAT) module and the histone deubiquit
188 eport that PCAF is a fork-associated histone acetyltransferase (HAT) that regulates the stability of
191 modifications, largely regulated by histone acetyltransferases (HAT) and histone deacetylases, have
193 ined by the antagonistic activity of histone acetyltransferases (HATs) and histone deacetylases (HDAC
197 cetyltransferases (KATs, also termed histone acetyltransferases, HATs) catalyze the acetylation of su
200 s such as DNA methyltransferases and histone acetyltransferases have revealed a critical role for epi
202 , ten-eleven translocation proteins, histone acetyltransferases, histone deacetylases, BET bromodomai
203 ing that it is the second identified protein acetyltransferase in B. subtilis We propose that at leas
204 out to investigate whether the main histone acetyltransferases in budding yeast, Gcn5 and Esa1, poss
205 nts, and the evolutionary origin of mannan O-acetyltransferases in land plants has not yet been studi
206 tion, and presence of functional polyamine N-acetyltransferases in S. aureus and E. faecalis represen
209 ells lacking p300 suggested that the histone acetyltransferase is a negative regulator of Hippo pathw
211 , we explore an emerging concept that lysine acetyltransferase (KAT) enzymes drive cellular plasticit
214 f the ubiquitin ligase HUWE1, or the histone acetyltransferase KAT5, top hits from our screens, robus
215 equired for the recruitment of the MYST-type acetyltransferase KAT7 to rDNA loci, resulting in enhanc
218 e compensatory induction of lecithin:retinol acetyltransferase (Lrat) or retinol dehydrogenase 11 (Rd
219 HIV-1 Tat-interacting protein 60 kDa (Tip60) acetyltransferase mediates acetylation at lysine residue
222 uvancy with a staphylococcal peptidoglycan O-acetyltransferase mutant reduces IL-10, increases IL-1be
223 vided a new molecular target, the N-terminal acetyltransferase Naa10p, for harnessing beige-fat bioge
224 be the role of an uncharacterized N-terminal acetyltransferase, NAA50, in the regulation of plant dev
225 ractor and regulator of the actin N-terminal acetyltransferase NAA80, and establish the modus operand
226 interaction partner of the actin N-terminal acetyltransferase NAA80, and further confirm this by ana
227 y identified as an unconventional N-terminal acetyltransferase (NAT) because it localizes to organell
234 HR), or channelrhodopsin-2 (ChR2) in Choline acetyltransferase neurons (ChAT(+)) or Arch in LIM-homeo
235 sion toxicity assays, we determined that the acetyltransferase NuA4 and deacetylase Rpd3 are primaril
236 n regulation in combination with the histone acetyltransferase NuA4 and histone H2A.Z exchanger SWR1.
239 ype methyltransferases by 2-fold but also an acetyltransferase of another enzyme category when linked
240 ins important for the recruitment of histone acetyltransferases of the MYST family to chromatin.
241 ins important for the recruitment of histone acetyltransferases of the MYST family to chromatin.
242 T signaling, which in turn activates histone acetyltransferase p300 (p300 HAT), leading to changes in
243 ly to the transcriptional regulators histone acetyltransferase P300 (p300), NFkappaB, and CCAAT enhan
244 in protein activation, including the histone acetyltransferase p300 acetylated in its activation loop
245 the transcriptional coactivator and histone acetyltransferase p300 and activates gene expression in
246 We found PARN is primarily acetylated by the acetyltransferase p300 at Lys-566 and deacetylated by si
248 horylation(17-19) stimulates activity of the acetyltransferase p300 in trans, suggesting that H3.3 ac
250 d multiple new players including the histone acetyltransferase p300 that was found to be a primary dr
251 tin association, and associates with histone acetyltransferase p300 to enhance Smad transcriptional a
254 nt evidence that FAAP20 is acetylated by the acetyltransferase p300/CBP on lysine 152, the key residu
255 l-CoA and isobutyryl-CoA interacted with the acetyltransferase P300/CBP-associated factor (PCAF) in l
256 ation was associated with elevated levels of acetyltransferase P300/CBP-associated factor (PCAF), whe
257 egradation system, we found that the histone acetyltransferases P300 and CBP maintained H3K27ac abund
258 creased by C646, an inhibitor of the protein acetyltransferases p300/CREB-binding protein (CBP).
259 by binding to the KIX domain of the histone acetyltransferase paralogues CREB-binding protein (CBP)
261 laphos resistance (BAR) and phosphinothricin acetyltransferase (PAT) genes, which convey resistance t
264 ated in algae, their recruitment as mannan O-acetyltransferases probably occurred in bryophytes, and
265 (DHHC3)' was incorrectly referred to as an 'acetyltransferase' rather than an as an 'acyltransferase
266 acting at an early step to regulate histone acetyltransferase recruitment, histone acetylation, and
267 mitoyltransferase ZDHHC3 (DHHC3) as the main acetyltransferase required for the palmitoylation of PD-
269 known to be N-terminally acetylated, and the acetyltransferases responsible for this modification bel
272 ne modifications as part of the Spt-Ada-Gcn5 Acetyltransferase (SAGA) transcriptional coactivator com
273 r affinity for its natural inhibitor, serine acetyltransferase (SAT), as compared with its affinity f
275 ced flux is driven by spermidine/spermine N1-acetyltransferase (SSAT) activity, which acetylates poly
277 permine oxidase and spermidine/spermine-N(1)-acetyltransferase (SSAT) when compared with 2,11-Me(2)Sp
278 campestris The P. syringae T3SE HopZ1a is an acetyltransferase that acetylates the pseudokinase AtZED
279 her, this study identifies the first histone acetyltransferase that activates ERalpha expression whic
281 2) that the Gcn5-related YiaC protein is the acetyltransferase that modifies CobB(L), and 3) that Yia
282 icant homology with some characterized sugar acetyltransferases that modify the C-4 amino group in th
284 ing phase of the circadian cycle, the lysine acetyltransferase TIP60 acetylates the transcriptional a
286 uced MARCKS acetylation at lysine 165 by the acetyltransferase Tip60, which is a prerequisite for its
288 c leukemia zinc finger protein (MOZ) histone acetyltransferase to the viral promoter, which promoted
289 that AtaT2 is the first GNAT (Gcn5-related N-acetyltransferase) toxin that specifically targets charg
290 ion control, four were not acetylated by two acetyltransferases used in this work, and two were acety
293 s canonical role as a cytoplasmic histone H4 acetyltransferase, we isolated a HAT1-containing complex
294 ce, rice and poplar were mannan 2-O- and 3-O-acetyltransferases, whereas the two group I DUF231 membe
295 e kinase1 (SphK1) is an acetyl-CoA dependent acetyltransferase which acts on cyclooxygenase2 (COX2) i
296 e discovery of five cytochrome P450s and two acetyltransferases which catalyze a cascade of reactions
297 cohesion requires the activity of the ESCO2 acetyltransferase, which modifies the Smc3 subunit of co
298 his study enhances our understanding of PG O-acetyltransferases, which could guide the development of
299 s as a platform for recruiting Tip60 histone acetyltransferase with increased H4 acetylation and subs
300 stained association of NFAT and p300 histone acetyltransferase with the IP-10 gene required p38 and c