ライフサイエンスコーパス: acquired immunity

1 "anti-CRISPR" proteins (Acrs) to counteract acquired immunity.

2 ating and inhibitory functions on innate and acquired immunity.

3 n immune function, involving both innate and acquired immunity.

4 cells (DCs) are key regulators of innate and acquired immunity.

5 lymphocyte responses and bridges innate and acquired immunity.

6 enes that play essential roles in innate and acquired immunity.

7 osal surfaces, thus directing and regulating acquired immunity.

8 is a key event in the control of innate and acquired immunity.

9 lymphocyte responses and bridges innate and acquired immunity.

10 ions to predominantly suppressive effects on acquired immunity.

11 endent manner and has pleiotropic effects on acquired immunity.

12 lls and complement participate in innate and acquired immunity.

13 licated in host responses in both innate and acquired immunity.

14 in host innate immunity and as regulators of acquired immunity.

15 ple signaling pathways regulating innate and acquired immunity.

16 l pathogens in advance of the development of acquired immunity.

17 ells, which are important in both innate and acquired immunity.

18 of the early events leading to induction of acquired immunity.

19 PGI(2), in the regulation of both innate and acquired immunity.

20 identical to corresponding maximal naturally acquired immunity.

21 ter the function of immune cells relevant to acquired immunity.

22 gen dissemination and for the development of acquired immunity.

23 te effector mechanisms, and the induction of acquired immunity.

24 required for optimal induction of protective acquired immunity.

25 7 broadly suppresses innate inflammation and acquired immunity.

26 e system that contributes to both innate and acquired immunity.

27 provide a means of enhancing both innate and acquired immunity.

28 providing a critical link between innate and acquired immunity.

29 d a major connecting link between innate and acquired immunity.

30 s provide a critical link between innate and acquired immunity.

31 can function as a bridge between innate and acquired immunity.

32 , intracellular pathogenesis, and innate and acquired immunity.

33 ons, although they may contribute to partial acquired immunity.

34 ession plays a vital role both in innate and acquired immunity.

35 ereby controlling subsequent polarization of acquired immunity.

36 d to have a critical role in both innate and acquired immunity.

37 poietic rescue but also augmented innate and acquired immunity.

38 Leptin plays a role in innate and acquired immunity.

39 ge, it is not known if LNs are essential for acquired immunity.

40 st defense burden from an innate response to acquired immunity.

41 on and may bridge the gap between innate and acquired immunity.

42 ccharide contribute to evasion of innate and acquired immunity.

43 -like cytokines that help mediate innate and acquired immunity.

44 matic mutation is a fundamental component of acquired immunity.

45 cules which contribute to the development of acquired immunity.

46 les in host defence and in the regulation of acquired immunity.

47 infection, mice were rechallenged to assess acquired immunity.

48 tal development, homeostasis, and innate and acquired immunity.

49 to partially evade either natural or vaccine-acquired immunity.

50 protein, which continually mutates to escape acquired immunity.

51 g risk factors for infection and the role of acquired immunity.

52 cific parasite antigens were associated with acquired immunity.

53 ion or vaccination play an important role in acquired immunity.

54 smissibility and, in some cases, escape from acquired immunity.

55 mune cell interactions to produce innate and acquired immunity.

56 The effect did not vary by naturally acquired immunity.

57 on is associated with reduction in naturally acquired immunity.

58 ector triggered immunity as well as systemic acquired immunity.

59 atory activity in cells mediating innate and acquired immunity.

60 oadly reduces innate inflammation as well as acquired immunity.

61 he spleen and are major targets of naturally acquired immunity.

62 which Abs play a critical role in naturally acquired immunity.

63 s, including receptor function in innate and acquired immunity.

64 ve incidence rates and evaluate evidence for acquired immunity.

65 to determine their contribution to naturally acquired immunity.

66 lex immunomodulatory functions in innate and acquired immunity.

67 ibility to malaria by compromising naturally acquired immunity.

68 olonization and the acquisition of naturally acquired immunity.

69 impact on both metabolism and development of acquired immunity.

70 several immune responses in both innate and acquired immunity.

71 gulating homeostatic immune architecture and acquired immunity.

72 but we lack an understanding of the role of acquired immunity.

73 sed health care workers and in patients with acquired immunity.

74 shaping protection or pathogenic sequelae of acquired immunity.

75 aft survival by suppressing inflammation and acquired immunity.

76 ptible to infection regardless of previously acquired immunity.

77 NF-kappaB plays a key role in innate and acquired immunity.

78 mental antigens (memory response) is termed "acquired" immunity.

79 s, is a fundamental suppressor of innate and acquired immunities.

80 ic settings with varying levels of naturally acquired immunity: a typical setting under which prevale

81 The Khmer migrants, with low acquired immunity, active on plantations and mines, repr

82 ibution of cross-priming to the induction of acquired immunity after DNA immunization.

83 two decades, and there is good evidence for acquired immunity after infection.

84 studying the roles of passively and actively acquired immunity against B. pertussis.

85 We investigated whether the presence of acquired immunity against E. phagocytophila precludes wh

86 Hence, Il6 is of critical importance for acquired immunity against M. tuberculosis infection.

87 e long been known to contribute to naturally acquired immunity against malaria, but their association

88 throcytes are important targets of naturally acquired immunity against malaria, but their high number

89 ut are rarely investigated in the context of acquired immunity against Plasmodium falciparum malaria.

90 hat are important for stimulating innate and acquired immunity against protozoal pathogens.

91 conclusions about the strength of naturally acquired immunity against rotavirus gastroenteritis (RVG

92 ested that discrepant estimates of naturally-acquired immunity against RVGE can be attributed, in par

93 he rhesus macaque provides a unique model of acquired immunity against schistosomes, which afflict >2

94 nd might result in the undermining of normal acquired immunity against T. cruzi.

95 uncover a nonredundant role for basophils in acquired immunity against tick infection.

96 The relative contribution of acquired immunity against various stages of the parasite

97 CRISPR-Cas systems provide prokaryotes with acquired immunity against viruses and plasmids, but how

98 CRISPR-Cas pathways provide prokaryotes with acquired "immunity" against foreign genetic elements, in

99 tory protein that participates in innate and acquired immunity, also serves as a receptor for viral a

100 ytes (PE), plays a central role in naturally acquired immunity, although antibodies to PfEMP1 are pre

101 is consistent with gradual risk reduction or acquired immunity amongst the highest risk individuals.

102 protein 3alpha (PvMSP3alpha) is a target of acquired immunity and a potential vaccine candidate.

103 arum are an important component of naturally acquired immunity and an important vaccine target.

104 mutations that escape vaccine- and infection-acquired immunity and antiviral drugs.

105 ll-like receptors (TLRs) activate innate and acquired immunity and are candidates for playing key rol

106 rulence factor that contributes to impairing acquired immunity and enhances susceptibility to reinfec

107 These findings suggest a role for naturally acquired immunity and highlight implications for surveil

108 ese Pfs230 domains were targets of naturally acquired immunity and immune sera from messenger RNA lip

109 Acquired immunity and inflammation are likely to be cruc

110 ere mostly induced and related to innate and acquired immunity and inflammation.

111 r allergic reactions, but also for innate or acquired immunity and inflammatory conditions that worse

112 etent APC is essential for the generation of acquired immunity and is a major function of adjuvants.

113 measures the intensity of antimycobacterial acquired immunity and is used to diagnose latent infecti

114 ndirect protection from SARS-CoV-2 infection-acquired immunity and its comparative strength and durab

115 d MSPDBL2 are important targets of naturally acquired immunity and might constitute potential vaccine

116 eremia, but little is known about maternally acquired immunity and natural exposure in infant populat

117 are complex and include host polymorphisms, acquired immunity and parasite virulence.

118 the context of the development of naturally acquired immunity and population infectivity.

119 cally infected euthymic mice, maintenance of acquired immunity and prevention of relapse required CD4

120 Acquired immunity and protective efficacy were also assa

121 Infection is maintained in spite of acquired immunity and resists eradication by antimicrobi

122 cuss recent advances in the understanding of acquired immunity and susceptibility to the two major pe

123 The primary site of expression of acquired immunity and the hallmark of tuberculosis is th

124 produced during the activation of innate and acquired immunity, and are the principal means for inter

125 demiology, diagnostics, disease attribution, acquired immunity, and innate susceptibility, and the gr

126 The complement pathway mediates innate and acquired immunity, and its activation drives the removal

127 to malaria among older children due to lower acquired immunity, and this has implications for ongoing

128 Innate and acquired immunity are critical in control of WNV, and in

129 Both innate and acquired immunity are likely to contribute to FCAVD.

130 biomarkers of malaria exposure and naturally acquired immunity are warranted in endemic settings wher

131 appear to play important roles in innate and acquired immunity as sensors of bacterial components.

132 lays a more pivotal antiviral role than does acquired immunity, as the antitumor effect of an oncolyt

133 ction of Abs arising in vaccine or naturally acquired immunity, as well of therapeutic mAbs.

134 therapy in Uganda are primarily mediated by acquired immunity associated with malaria transmission i

135 nduced immunity, they develop more sustained acquired immunity at 6 months post-vaccination.

136 early in B. bronchiseptica infection and by acquired immunity at later time points and suggest that

137 tween vaccine-induced immunity and naturally acquired immunity at the population level has been under

138 ages play a critical role in both innate and acquired immunity because of their unique ability to int

139 ay also play a key role in the regulation of acquired immunity, because CR2 is mainly localized on B

140 Infection-acquired immunity boosted with vaccination remained high

141 mmunity and instructs the development of the acquired immunity but also leads to the detrimental infl

142 stem plays a central part in both innate and acquired immunity, but the contribution of complement ac

143 Macrophages control innate and acquired immunity, but their role in severe asthma remai

144 hese results indicate that activation of the acquired immunity by a periodontal pathogen reduces the

145 ut infection and can limit the expression of acquired immunity by a variety of pathways.

146 mmatory sites may restrain the activation of acquired immunity by blocking DC development and migrati

147 e host infections in some individuals versus acquired immunity by others, using complex metapopulatio

148 hese results indicate that activation of the acquired immunity by P. gingivalis increases the inflamm

149 Zinc deficiency also affects development of acquired immunity by preventing both the outgrowth and c

150 rate that both vaccine-derived and infection-acquired immunity can reduce SARS-CoV-2 transmission whi

151 an important role for this T-cell subset in acquired immunity conferred by M. bovis BCG vaccination.

152 CD4(+) T-cell-dependent acquired immunity confers antibody-independent protectio

153 Naturally acquired immunity confers stronger protection against in

154 of CD169(+) macrophages in the activation of acquired immunity could benefit the design of vaccinatio

155 Vertebrate acquired immunity could have therefore originated from l

156 a disease for which there is no evidence of acquired immunity could prove extremely costly in the lo

157 of the Tag7-Hsp70 complex and TNF-alpha, an acquired immunity cytokine.

158 thin this region of CS, suggesting naturally acquired immunity does induce variant-specific selection

159 ry neuropeptides that affect both innate and acquired immunity, down-regulate IL-12 p40 and inducible

160 veloped a model that allows visualization of acquired immunity during and following antibiotic treatm

161 m more expansive and granular assessments of acquired immunity during early phase 1 immunogenicity tr

162 ave been preadaptations for the evolution of acquired immunity during the early vertebrate radiation.

163 as been recently linked to the production of acquired immunity effectors such as antibodies.

164 tal role at the interface between innate and acquired immunities following their recruitment to infla

165 bacterial infection, but the acquisition of acquired immunity following successful treatment has rar

166 h family on April 14, 2021 (index date), who acquired immunity from a previous COVID-19 infection or

167 de registries in Sweden, all individuals who acquired immunity from either previous COVID-19 infectio

168 tes from NK-depleted animals transferred the acquired immunity generated with C3L5-CK beta 11 vaccina

169 Although acquired immunity has been shown to be crucial during CH

170 bsets in response to mediators of innate and acquired immunity have also been found in plaques.

171 oderma and provide support for the idea that acquired immunity helps to control naturally occurring c

172 ncluding genetic disease drivers, innate and acquired immunity, hypoxia sensing, and angiogenesis sig

173 lassic signaling is important for innate and acquired immunity, IL-6 trans-signaling has been linked

174 a relationship could be demonstrated between acquired immunity in experimental rabbit syphilis, serum

175 Characterisation of protective helminth acquired immunity in humans or experimental models has f

176 state sources and decreased transplacentally acquired immunity in infants.

177 re importantly, their relevance to naturally acquired immunity in longitudinal cohort studies (LCSs)

178 CRISPR-Cas systems provide acquired immunity in prokaryotes.

179 IFN-gamma, was necessary for suppression of acquired immunity in Rag(-/-) reconstituted mice.

180 and suggests either undetected infection or acquired immunity in the absence of infection.

181 nts of SARS-CoV-2 became less pathogenic and acquired immunity in the host provided protection, at le

182 ique opportunities for augmenting innate and acquired immunity in the human newborn.

183 ally contribute to early stages of naturally acquired immunity in the owl monkey model.

184 dence for the involvement of both innate and acquired immunity in the pathogenesis of AA.

185 udies have begun to elucidate differences in acquired immunity in tissues of the human female reprodu

186 MHC loci encode peptides that initiate acquired immunity in vertebrates, making them likely can

187 by affecting multiple aspects of innate and acquired immunity, including interfering with complement

188 ltiple effector cells of innate immunity and acquired immunity, including macrophages, dendritic cell

189 show that both vaccine-derived and naturally acquired immunity independently reduce the infectiousnes

190 show that both vaccine-derived and infection-acquired immunity independently yield indirect protectio

191 e the virulence, inflammatory potential, and acquired immunity induced by strains producing underacyl

192 ative vaccination." Vaccination (or actively acquired immunity) involves the presentation of both a f

193 is that aberrant activation or regulation of acquired immunity is central to the pathogenesis of this

194 These findings suggest that naturally acquired immunity is characterized by different cell typ

195 essure toward antigenic variation exerted by acquired immunity is counterbalanced by a survival advan

196 eisseria meningitidis evades host innate and acquired immunity is crucial.

197 sis that the slow development of schistosome-acquired immunity is due to the slow accumulation of res

198 Furthermore, CD4+ and CD8+ T-cell-dependent acquired immunity is essential for long-term survival of

199 herefore, acquisition of strain-specific age-acquired immunity is partially directed against polymorp

200 when the duration of naturally- and vaccine-acquired immunity is short, when there is population mix

201 dies of human disease suggest that naturally acquired immunity is the predominant outcome of Leishman

202 The mechanism of acquired immunity is unknown.

203 e of dendritic cells (DC) in both innate and acquired immunity is well recognized in the mammalian im

204 ansmissibility and the duration of naturally-acquired immunity, is essential in estimating the impact

205 oid cells with important roles in innate and acquired immunity: macrophages, mast cells and neutrophi

206 cted subcutaneously into cattle and that the acquired immunity markedly enhanced resistance to experi

207 uption of cells important in both innate and acquired immunity may contribute to the overall immune d

208 ely susceptible BALB/c mice, suggesting that acquired immunity may play an important secondary role.

209 Naturally acquired immunity (NAI) protects against malaria in adul

210 alence tend to have high levels of naturally acquired immunity (NAI) to severe malaria; NAI is caused

211 unique opportunity to investigate naturally acquired immunity (NAI).

212 er-induced CNV is not primarily dependent on acquired immunity, nor does the fundus injury affect per

213 neage play a central role in both innate and acquired immunity of the host.

214 the host for life in the presence of strong acquired immunity, often exhibiting periodic reactivatio

215 To account for the possible effects of acquired immunity on half-life, we used three surrogates

216 ence of infection/disease or the patterns of acquired immunity or innate resistance to norovirus.

217 ts suggest that immune cells associated with acquired immunity play a role in regulating motoneuron s

218 cessation of treatment due to the absence of acquired immunity post infection.

219 atabodies) could degrade toxic proteins, but acquired immunity principles have not provided evidence

220 amined the long-term protection of naturally acquired immunity (protection conferred by previous infe

221 Infection-acquired immunity provides 38% (24-50%) indirect protect

222 onella may interfere with the development of acquired immunity, providing insights into the complex n

223 age children: both reduced water contact and acquired immunity reduces infection in adults.

224 .In addition to these developments regarding acquired immunity, refinements to our understanding of i

225 rf7 and Cxcl9; 7 and 60 days post infection, acquired immunity-related genes, such as Cd3g and H2-Aa;

226 ails their epidemic growth in the absence of acquired immunity remains unknown.

227 Naturally acquired immunity results in a 69% reduction in the risk

228 ution of B-1a and B-1b subsets to innate and acquired immunity reveals an unexpected division of labo

229 st that malaria vaccines mimicking naturally acquired immunity should ideally induce antibody respons

230 Furthermore, autophagy is involved in acquired immunity, such as antigen processing for MHC II

231 the innate immune response to UPEC stimulate acquired immunity that facilitates enhanced clearance up

232 modulated by density-dependent transmission, acquired immunity that is lost over time, and recrudesce

233 at Chlamydia trachomatis infection engenders acquired immunity, the basis for which is incompletely d

234 n rollout speeds, and estimates of naturally acquired immunity, this framework can be used to compare

235 munity against MmuPV1 after colonization and acquired immunity through the transfer of T cells from i

236 rotypes can circumvent preexisting naturally acquired immunity to AAV.

237 n of antibody responses with both innate and acquired immunity to amebiasis indicate that CD4+ T cell

238 that TH1 polarization has a primary role in acquired immunity to C. jejuni.

239 This review describes the generation of acquired immunity to C. trachomatis and focuses on how T

240 ia are common, which suggests that naturally acquired immunity to CMV does not alter shedding pattern

241 at Russian adults, who were unlikely to have acquired immunity to diphtheria through immunization or

242 Naturally acquired immunity to HSV involves T cell recognition of

243 sting that the extremely slow development of acquired immunity to human schistosomes may depend on ex

244 ortant sources of interferon (IFN)-gamma for acquired immunity to intracellular pathogens, but they c

245 Naturally acquired immunity to malaria develops only after many ye

246 Naturally acquired immunity to malaria develops slowly, requiring

247 Acquired immunity to malaria develops with increasing ag

248 Acquired immunity to malaria is inefficient, even after

249 understanding of the mechanisms of naturally acquired immunity to malaria may lead to insights for va

250 Acquired immunity to malaria therefore prioritises host

251 PfEMP1 are important targets of acquired immunity to malaria, and through evolution, the

252 ng in the spleen, are thought to orchestrate acquired immunity to malaria, but it is not known how th

253 is understanding the mechanisms of naturally acquired immunity to malaria.

254 ected RBCs by NK cells may be a mechanism of acquired immunity to malaria.

255 ought to play an essential role in naturally acquired immunity to malaria.

256 ily of clonally variant targets of naturally acquired immunity to malaria.

257 elerate efforts to unravel the mechanisms of acquired immunity to malaria.

258 omewhat impaired in their ability to develop acquired immunity to MoPn, again indicating a role for t

259 Acquired immunity to murine Chlamydia trachomatis genita

260 pecific immunity stabilizes competition, and acquired immunity to noncapsular antigens reduces fitnes

261 CRISPR-adjacent genes or the propagation of acquired immunity to other bacteria in the population, r

262 DBPII and implicate this molecule in partial acquired immunity to P. vivax in endemic populations.

263 DBPII and implicate this molecule in partial acquired immunity to P. vivax in populations in endemic

264 antibody responses to DBP correlate with age-acquired immunity to P. vivax, antibodies to recombinant

265 rtant yet understudied effector mechanism in acquired immunity to PAM.

266 cancer immunotherapy by capitalizing on pre-acquired immunity to pathogens to convert a weak antitum

267 Elucidating the mechanisms of naturally acquired immunity to Plasmodium falciparum infections wo

268 Acquired immunity to Plasmodium falciparum malaria is ma

269 It is unclear whether naturally acquired immunity to Plasmodium falciparum results from

270 Naturally acquired immunity to Plasmodium falciparum's asexual blo

271 ABTs clear pneumococcal colonization or that acquired immunity to pneumococci is an accumulation of i

272 D-19) risk factors, the ability of naturally acquired immunity to prevent reinfection among patients

273 the virus to reinfect individuals that have acquired immunity to previously circulating strains thro

274 the occurrence and persistence of adaptive, acquired immunity to primary or cross-reactive infection

275 nsistent with cooperation between innate and acquired immunity to promote a pattern of homing recepto

276 ng that gammadelta T cells can contribute to acquired immunity to S. dublin.

277 nt study we evaluated the role of B cells in acquired immunity to Salmonella infection by using gene-

278 suggest that the primary role of B cells in acquired immunity to Salmonella is via the development o

279 The trajectories of acquired immunity to severe acute respiratory syndrome c

280 re likely to represent a common mechanism of acquired immunity to severe malaria and offer novel insi

281 Acquired immunity to Streptococcus pneumoniae (pneumococ

282 antigens have been associated with naturally acquired immunity to symptomatic malaria.

283 eating a long-term, disease-free state, with acquired immunity to the tumor functioning as an essenti

284 l for the study of infection and vaccination-acquired immunity to this agent.

285 parum malaria in part by enhancing naturally-acquired immunity to this disease.

286 A thorough understanding of acquired immunity to ticks is essential for rational dev

287 T cells may play a role in innate as well as acquired immunity to tumors and infectious pathogens.

288 However, its role in regulating acquired immunity to viral pathogens and neuropathogenes

289 bility that extend from classical innate and acquired immunity to weaknesses in constitutional resist

290 pational exposure to HBV and in patients who acquired immunity via HBV infection.

291 Infection-acquired immunity waned after 1 year in unvaccinated par

292 Evidence of acquired immunity was observed among GII infections only

293 Evidence of acquired immunity was observed even in the absence of ge

294 rom that of wild-type cells, confirming that acquired immunity was required for clearance in C3H/HeN

295 d waning patterns for vaccine- and infection-acquired immunity, we estimate population immunity again

296 proportion of the population with naturally acquired immunity, we used either the reported seropreva

297 Immune components necessary for this acquired immunity were identified.

298 s in malaria transmission decrease naturally acquired immunity, which may influence the emergence of

299 , accelerating the development of protective acquired immunity, which would take many years to develo

300 or nonspecific activation of both innate and acquired immunity will be necessary for further developm