ライフサイエンスコーパス: act through

1 nd 15-deoxy-Delta(12,14)-prostaglandin J(2), act through 2 GPCRs, d-type prostanoid 1 and the chemoat

2 We propose that hopanoids act through a combination of hydrophobic and inter-lipid

3 Axon guidance is proposed to act through a combination of long- and short-range attra

4 ion in the injured tissue, suggesting it may act through a combination of TLR7/8/9 and ERK signaling

5 shear-dependent increases in ATP, which can act through a diverse portfolio of purinergic signaling

6 replication and episome persistence and may act through a host cell partner(s) other than a BET prot

7 tic studies revealed that the lead compounds act through a mechanism distinct from that of traditiona

8 rounding tissue, suggesting that YAP and TAZ act through a mechanism of cell competition to eliminate

9 ted that many AF-associated genetic variants act through a mechanism of impaired muscle cell differen

10 ntegrity and that they therefore most likely act through a mechanism other than HI.

11 n of proatherogenic circulating factors that act through a meta-organismal endocrine axis to impact C

12 and larval developmental stages, where they act through a multi-faceted mechanism.

13 Dimerization did not act through a physical clustering-based kinase activatio

14 neuroprotective properties of microvesicles act through a trophic support mechanism that reduces inf

15 electrophysiology to show that electrophiles act through a two-step process in which modification of

16 s sequence similarity with SynDIG1, it might act through a unique mechanism as an auxiliary factor fo

17 enetic studies suggest that these inhibitors act through a unique pH-sensing intersubunit interface i

18 ypes showed altered microtubule dynamics and acted through a dominant toxic gain of function mechanis

19 TGF-beta acted through a JNK-dependent, Smad4-independent pathway

20 S6K in turn acted through a negative feedback loop to restrain Akt3

21 Hedgehog proteins are pivotal morphogens acting through a canonical pathway involving first activ

22 efficacious and safer drugs, preferentially acting through a different mechanism of action and direc

23 lesterol-dependent apoptosis in podocytes by acting through a dual mechanism that required a reductio

24 st alpha-glucosidase (IC(50) = 1.53 mug/mL), acting through a non-competitive inhibitory mechanism.

25 sting that the Notch intracellular domain is acting through a novel mechanism.

26 at PGC1alpha suppresses melanoma metastasis, acting through a pathway distinct from that of its bioen

27 We hypothesize that the fusion protein acts through a dominant-negative mechanism to cause this

28 ntity in adult ovarian somatic cells, but it acts through a Dsx(M)-independent mechanism.

29 SOBIR1/EVR acts through a mechanism that involves BREVIPEDICELLUS (

30 n the ethylene and cytokinin pathways, which acts through a phosphorelay mechanism.

31 It acts through a recently identified orphan member of the

32 tion of the hormone abscisic acid (ABA) that acts through a receptor-signal transduction pathway comp

33 Serotonin acts through a signal transduction pathway conserved bet

34 show that fever acts through a T cell-intrinsic SMAD4-dependent mechanis

35 We propose a model in which drought acts through ABA to increase ABIG1 transcription which i

36 mature brown adipocytes also suggests mTORC2 acts through ACLY to increase carbohydrate response elem

37 Noradrenaline acts through adrenergic receptors (ARs), of which beta2-

38 sequestration of miR165/6, a conserved miRNA acting through AGO1.

39 inhibition, suggesting that the inhibitor is acting through AKT signaling pathways.

40 sites in an orthosteric manner, but also to act through allosteric mechanisms arising from distant s

41 stabilize inactive kinase conformations, or act through allosteric sites.

42 results of this study suggest that nicotine acts through alpha7-nAChR and plays a novel role in the

43 Medications that act through alternative molecular mechanisms are critica

44 Y1 receptors by PolyP reduced calcium signal acting through AMPA receptors, thus protecting neurons a

45 l ganglion cell (RGC) intrinsic excitability acting through AMPK-dependent inhibition of NKCC1 activi

46 Surprisingly however, Notch does not act through an apicobasal activity gradient as previousl

47 e and the motor state of head undulations by acting through an acetylcholine-gated channel and a musc

48 dence that GM-CSF drives CCL17 production by acting through an IFN regulatory factor 4-dependent (IRF

49 cterized NDN as a potent anorexigenic signal acting through an uncharacterized endozepine G protein-c

50 dependence or reward behavior, suggesting it acts through an alternative mu-opioid receptor target.

51 ndent inhibition of lateral root development acts through an EIN2-independent mechanism.

52 cium-activated protein for secretion (CAPS)] acts through an inhibitory pathway not explained by prev

53 We demonstrate that H2O2 acts through an Src kinase to activate a negative regula

54 ovel APC:Axin interaction site, and (2) GSK3 acts through APC motifs R2 and B to regulate APC:Axin in

55 The plant signaling molecule auxin, acting through AUXIN RESPONSE FACTOR (ARF) transcription

56 Surprisingly, we find that 5-FU and FUDR act through bacterial ribonucleotide metabolism to elici

57 Mechanistically, Blimp-1 acts through Bcl6, leading to increased GATA3 expression

58 Y5 physically interacts with and genetically acts through BIN2 to inhibit hypocotyl elongation.

59 absence of Hh by elimination of Cos2, likely acting through binding the CORD domain of Ci, or PKA, re

60 g PD-1, such as pembrolizumab and nivolumab, act through blockade of the PD-1-PDL-1 interaction.

61 We find that Hedgehog acts through Bmp to delineate the position of the circum

62 gE-mediated mechanisms, LMW agents appear to act through both immunological and non-immunological mec

63 Simultaneously stimulating receptors that act through both mechanisms showed synergistic inhibitor

64 The findings indicate I3C may be acting through both AHR-dependent and -independent mecha

65 interferon (IFN) response is controversial - acting through both positive and negative regulatory mec

66 These data suggest that GABA, acting through both presynaptic GABAA and GABAB receptor

67 a regulatory circuit involving FBXL5 and CIA acts through both IRPs to control iron metabolism and pr

68 In muscle, IL-13 acts through both its receptor IL-13Ralpha1 and the tran

69 Clinically used endotamponade agents act through buoyancy forces, yet can result in prolonged

70 feedback regulated by intracellular Ca(2+) , acting through calmodulin to facilitate channel opening.

71 scription-activating function of DHX9, which acts through cAMP response elements (CREs), suggesting t

72 vidence that rapamycin increased survival by acting through canonical pathways, including mitochondri

73 RPV1, causing local production of AEA, which acts through CB2.

74 increasing endometriosis risk in this region act through CDC42, but further functional studies are re

75 Here we show that LAR-RPTPs act through cellular inhibitor of apoptosis protein 1 (c

76 se other inhibitor resistance mutations also act through changes at Ser(130) and such changes drastic

77 CCHC14 and DNA methylation suggest the locus acts through changes to regulatory elements.

78 Many cardioprotective strategies act through common end-effectors and may be suboptimal i

79 ctivators forms a hexameric AAA+ ATPase that acts through conformational changes brought on by ATP hy

80 In photolytic cleavage those forces act through control of the ribose conformation and are t

81 describes a cellular mechanism by which LEN, acting through CRBN and IKZF1, has cytotoxic effects in

82 ective antagonist CP-154526, suggesting Ucn1 acts through CRF-R1 when promoting chondrocyte survival.

83 Nevertheless, different ligands acting through cross-wired pathways often lead to differ

84 egative regulation of virulence by GacS/GacA acts through csrB sRNA, which binds to CsrA and neutrali

85 ssential regulators of myotube guidance that act through cytoskeletal regulatory proteins to pattern

86 t of population density on reproductive span acted through DAF-16-dependent and DAF-16-independent pa

87 suggesting that FDA-approved ADHD drugs may act through different mechanisms than those underlying A

88 iral RNA polymerase gene A24R, which seem to act through different mechanisms to increase virus repli

89 ficity to the different responses, it should act through different transduction pathways and/or in co

90 a novel epigenetic silenced tumor suppressor acting through direct regulation of p53 transcription an

91 We report that sorafenib also acts through direct immune modulation, indispensable for

92 The JNK-JUN pathway does not act through directly inhibiting the DE enhancers.

93 emes, and that cholesterol-modified Hedgehog acts through Dispatched to increase cytoneme occurrence.

94 us, different combinations of Dscam proteins act through distinct mechanisms in closely related neuro

95 here, we demonstrate that different stimuli act through distinct pathways.

96 e (AC) activity relies on multiple effectors acting through distinct binding sites.

97 Hundreds of common genetic variants acting through distinguishable physiologic pathways infl

98 e that VOCs produced by P. polymyxa KM2501-1 act through diverse mechanisms to control M. incognita.

99 e-by-fatty acid interactions on blood lipids act through DNA methylation.

100 he gene-by-diet interactions on blood lipids act through DNA methylation.

101 Finally, we find that JH acts through dopaminergic neurons and conclude that an E

102 Lastly, we show that P0Q215X acts through dose-dependent gain of abnormal function, a

103 ttractive class of antimicrobial agents that act through dysregulation of caseinolytic protease (ClpP

104 y suggested that RBR repression specifically acts through E2FB.

105 uman cultural and socioeconomic drivers, may act through ecological and evolutionary processes differ

106 Here, we report that VEGF signaling, acting through ectoderm-derived VEGF3 and its cognate re

107 homology domain interacting protein (PHIP), acting through effects on the force transduction layer o

108 We assessed the role of endothelin-1, acting through endothelin A (ET(A) ) receptors, in modul

109 y JAM-A, a component of tight junctions that acts through EPAC to up-regulate the expression of claud

110 s modifiers (genetic or environmental) could act through epigenetic changes, such as DNA methylation

111 e transcripts are candidate targets of VAL1, acting through epigenetic and/or transcriptional repress

112 rovide a novel mechanism by which estrogens, acting through ER+ astrocytes in the brain microenvironm

113 a lesser extent 17alpha-estradiol, possibly acting through ER-X, prevented this effect.

114 wall and in the inter-ovule spaces, where it acts through ERL1 and ERL2.

115 We propose that E2, acting through estrogen receptor-beta, transactivates sy

116 t KTN0073 as a novel IgG2-based MET mAb that acts through exon 14-independent mechanisms to degrade t

117 idopsis thaliana), the photoperiodic pathway acts through FLOWERING LOCUS T (FT) to promote floral in

118 JNK3 acts through Forkhead box O3 (Foxo3a) to suppress the ac

119 Annexin A1 (AnxA1) mainly acts through Formyl Peptide Receptor 2 (FPR2) inducing t

120 Acting through FOXA1, LSD1 inhibition broadly disrupted

121 recruitment and appropriate host defense and act through G protein-coupled receptors (GPCRs), which i

122 ible hormonal factors, the majority of which act through G protein-coupled receptors.

123 , mechanical cues, and hormonal signals that act through G-protein-coupled receptors.

124 of metabolites have signaling properties by acting through G-protein-coupled receptors.

125 n, and anxiety disorders such as depression, acts through G-protein-coupled receptors (GPCRs) known a

126 The C9ORF72 mutation acts through gain- and loss-of-function mechanisms to in

127 M3, demonstrating that the receptors did not act through Galpha(i/o) or through the major protein kin

128 ecific to asymmetric division and whether it acts through Galpha to promote furrowing are unclear.

129 In wild-type animals Ang II acting through Galphaq protein-coupled receptors down-re

130 a) is negatively regulated by angiotensin II acting through Galphaq protein-coupled receptors.

131 nts associated with ADHD and ASD that likely act through gene regulation.

132 cal synapse, while the disinhibitory pathway acts through glutamatergic chemical synapses.

133 mu-Opioids act through GPCRs that are generated from the Oprm1 gene

134 our studies suggest that cytoskeletal forces acting through GPIbalpha are involved in maintaining pla

135 The KSHV-encoded vGPCR acts through Gq/11 and G12/13 to inhibit the Hippo pathw

136 clusters in cultured myotubes via PI3 kinase acting through GSK3beta.

137 FKBP51 acts through GSK3beta on the downstream targets Tau, bet

138 Mutant, truncated A20 proteins are likely to act through haploinsufficiency because they do not exert

139 n vitro reconstitution indicate that hypoxia acts through HIF-independent mechanisms that increase bi

140 he existence of growth-regulating mechanisms acting through IGF-related genes in ways that are not re

141 Each of these neurohormonal derangements may act through increased activity of both NHE1 and NHE3.

142 re consistent across the cortical hierarchy, acting through increased and stabilized neuronal excitab

143 Next-generation antiandrogens act through inhibiting androgen synthesis (abiraterone)

144 We demonstrated that ebselen acts through inhibition of protein synthesis and subsequ

145 Here, we show that TIMP3 acts through inhibition of the metalloprotease ADAM17 an

146 Acting through intestinal bHLH-PAS domain proteins Metho

147 ovide a novel mechanism of tumor growth that acts through intracellular Ca(2+) levels to modulate JNK

148 ophosphatidic acid (LPA) in decidualization, acting through its G-protein-coupled receptor LPA3 in th

149 rogesterone suppresses uterine contractility acting through its receptors (PRA/B).

150 a post-transcriptional repressor of T cells, acting through its ROQ domain to destabilize mRNA target

151 The American Bar Association, acting through its Standing Committee on Gun Violence, c

152 The secreted neurorepellent Slit2, acting through its transmembrane receptor, Roundabout (R

153 ed Ccn1(DeltaHep) mice, indicating that CCN1 acts through its alpha6beta1 binding sites in this conte

154 potent growth and metastasis suppressor that acts through its inhibitory effects on a wide variety of

155 We conclude that GH acts through its receptor in the liver to activate autop

156 RA acts through its receptor RARalpha to repress transcript

157 olic switch upregulate interleukin 33, which acts through its receptor ST2 to activate both choroidal

158 ed by the stomach during fasting periods and acts through its receptor, the growth hormone secretagog

159 t here that secreted semaphorin 2b (Sema-2b) acts through its transmembrane receptor Plexin B (PlexB)

160 We demonstrated that glutamate acts through kainic acid receptors in the VMH to augment

161 recruitment of NAc shell dynorphin neurons, acting through KOR, is necessary and sufficient to drive

162 lin-41 acts through lin-29a, an isoform of a conserved Zn finge

163 These results establish that NNI2 inhibitors act through long range allosteric effects, reveal import

164 bility that p53 enhancers could be generally acting through long distances.

165 Here we show that acting through machines changes the way people solve the

166 lts suggest that KAP1 Ser473 phosphorylation acts through MFN2 reduction to restrict mitochondrial hy

167 on of multivesicular release, P/Q-type VGCCs act through microdomain signaling to recruit additional

168 Thus, vitamin K antagonists act through mimicking the key interactions and conformat

169 e-like cells stimulated with mOSM (therefore acting through mLIFR), microarray expression profiling a

170 g is effective in enhancing vWM in aging and acts through modifications at different stages of stimul

171 prominent intrinsic regulator of mTORC1 that acts through modulation of RHEB (Ras homologue enriched

172 nt of severe pain depends heavily on opioids acting through mu opioid receptors encoded by the Oprm1

173 during evolution, a transcription factor can act through multiple mechanisms to generate a common beh

174 red evidence that the most potent inhibitors act through multiple mechanisms.

175 se converge on a single molecular pathway or act through multiple pathways to trigger neurodegenerati

176 Since that time, BAs have been shown to act through multiple receptors (PXR, VDR, TGR5 and S1PR2

177 cally costly, a rise in intracellular Ca(2+) acts through multiple pathways to increase ATP synthesis

178 y during prolonged exposure to pheromone and acts through multiple substrates to down-regulate yeast

179 en together, these results suggest that S6K1 acts through multiple targets of the mTOR pathway to pro

180 ANP acting through natriuretic peptide receptor-A (NPRA) low

181 laborative functions of IL-17 and IFN-gamma, acting through neutrophils and macrophages, respectively

182 Here, we identify a new pathway that acts through NIMA-related kinase 6 (Nek6) and Hsp72 to p

183 (-/-) mouse, we demonstrate that type I IFNs act through nonepithelial cells, including macrophages,

184 nflammatory function of the compound largely acts through Nrf2.

185 more, in agreement with the notion that IL-6 acts through osteocalcin, we demonstrate that mIL-6 prom

186 cally diverse and clinically essential drugs act through overlapping and distinct mechanisms to poten

187 cies surveyed, winter temperature appears to act through overwinter mortality of juveniles or as a cu

188 g the NRF2-mediated induction of MDM2, which acts through p53-dependent and -independent mechanisms t

189 entified FXa as potent platelet agonist that acts through PAR-1.

190 The activated Akt acted through phosphatidylinositol 3-phosphate 5-kinase

191 Specifically, elevated membrane tension acts through phospholipase D2 (PLD2) and the mammalian t

192 onzalez et al. (2016) show that PDGFA, which acts through PI3K-Akt pathways, plays a vital role in th

193 tabilized by biophysical feedback mechanisms acting through pore characteristics and microbial access

194 esthetics and classical benzodiazepine drugs act through positive modulation of gamma-aminobutyric ac

195 h deregulated MYC on the kinase NUAK1, which acts through PP1 and PNUTS to ensure that splicing keeps

196 s cue-induced feeding, and suggest orexin is acting through prefrontal cortical and thalamic sites to

197 ctively enhanced by cholinergic interneurons acting through presynaptic nicotinic acetylcholine recep

198 The parathyroid glands acting through PTH play a critical role in the regulatio

199 irect changes in cell physiology rather than acting through rare mutations.

200 Mechanistically, MOF/FAO inhibition acts through reducing mitochondrial respiration (i.e., O

201 ding one tryptophan residue W127 that likely acts through regulating nucleic acid binding.

202 nd kinase (STRIPAK) complexes that appear to act through regulation of protein phosphatase 2A (PP2A),

203 driver of angiomyolipoma tumor development, acting through regulation of CYR61.

204 TCER-1 acts through repression of PMK-1 as well as PMK-1-indepe

205 Mechanistically, Slit2 acting through Robo1 and Robo2 promoted the migration of

206 terpenes, particularly pinenes, promote SAR, acting through ROS and AZI1, and likely function as info

207 Thus, gut microbiota acting through SCFAs are important determinants of enter

208 ortant drivers of the domestication process, acting through selective enrichment of specific taxa, in

209 are organized into autonomous subgroups and act through separate mechanisms.

210 inant of meiotic recombination hot spots and acts through sequence-specific DNA binding via its C2H2

211 As a consequence, a single peptide can act through several mechanisms depending on the peptide'

212 Many signaling pathways act through shared components, where different ligand mo

213 have been developed to study cellular forces acting through single mechano-sensitive receptors.

214 man cells requires many hundreds of proteins acting through sophisticated multistep mechanisms.

215 Mechanistically, we show that Plk4 acts through Spd2 phosphorylation, which induces centrio

216 is in Foxf1(WT/S52F) mice.Conclusions: FOXF1 acts through STAT3 to stimulate neonatal lung angiogenes

217 MBP(84-104) acts through sustained co-activation of metabolic, estro

218 h, we show that dorsally derived Fgf signals act through Tbx16 and Tbxta to induce slow and fast trun

219 lex binding to the Pygo chromatin reader and acting through TCF/LEF-responsive enhancers.

220 Vitamin C potentiates TET activity and acts through Tet2/Tet3 to increase the stability of Foxp

221 ered the underlying pathway: both treatments act through the A2b receptor and specifically activate t

222 Molecular analysis revealed that Fzd7 may act through the activation of Wnt/beta-catenin and Jagge

223 se in local production of kynurenines, which act through the AHR to impair neutrophil chemotaxis.

224 (9)-tetrahydrocannabinol (THC), CBD does not act through the cannabinoid type 1 (CB1) receptor but ha

225 COR, MJ, and JA-Ile act through the canonical JA receptor COI1 in clock regu

226 rescribed anti-inflammatory compounds, which act through the glucocorticoid receptor (GR).

227 Our findings suggest that 17alpha-E2 may act through the liver and hypothalamus to improve metabo

228 virulence determinants, indicating ClpC may act through the mRNA modulatory activity of MazEF.

229 by mouse macrophages, suggesting that it may act through the PAF/PAF receptor pathway previously show

230 phosphatases (Ssu72, Rtr1, and Fcp1), which act through the post-translational modification of the C

231 no acids are a key input to this system, and act through the Rag GTPases to promote the translocation

232 such as Z-d-Phe, are less effective but may act through the same mechanism.

233 However, whether AJs and Scrib act through the same or independent mechanisms to regula

234 These proteins act through the same pathway to influence PS-ASO activit

235 oactive lipids (TXA2 and isoprostanes) which act through the thromboxane receptor (TP).

236 st that NLP7 controls the release of BLCs by acting through the cell wall-loosening enzyme CEL5.

237 vel regulator of WPB exocytosis, most likely acting through the downstream effectors ACAP2 and Arf6.

238 Thus, ET-1, acting through the ET(A) receptors, contributes to the c

239 BA are important metabolic regulators acting through the farnesoid X receptor and TGR5 recepto

240 terest and represent a prototype of proteins acting through the formation of protein-lipid or toroida

241 radiation, and CPR-4 seems to exert RIBEs by acting through the insulin-like growth factor receptor D

242 ere we show that the transverse tarsal arch, acting through the inter-metatarsal tissues, is responsi

243 Hippo kinase cascade is mediated by Hpo/Mst acting through the intermediary kinase Wts/Lats to phosp

244 gonists, notably lysophosphatidic acid (LPA; acting through the LPA1 receptor) and endothelin.

245 bolishes RocA function, consistent with RocA acting through the modulation of CovS activity.

246 recognized as a key regulator of autophagy, acting through the modulation of pathways such as the me

247 been previously implicated as a general acid acting through the N1 position in other ribozymes such a

248 decreases ribbon size respectively, possibly acting through the NAD(H)-binding domain on Ribeye.

249 nucleotides (ASOs) can reduce mRNA levels by acting through the no-go decay pathway.

250 he maintenance of germline chromatin, likely acting through the nuclear RNAi pathway.

251 of fire and herbivores is accounted for, as acting through the perimeter of the tree clusters, the p

252 er, these results indicate that the exocyst, acting through the primary cilium, is necessary for rena

253 GDNF, acting through the receptor tyrosine kinase Ret, regulat

254 proteins with a wide array of functions and acting through the recognition of proline-rich sequences

255 Acting through the repression of SOX4, PKA activation pr

256 the GFP-fused glucocorticoid receptor (GR), acting through the same HREs, displayed a profile consis

257 mechanism for the discrimination of ligands acting through the same receptor.

258 creased the proliferation of antitumoral M1, acting through the SEMA3A receptor neuropilin 1.

259 on brain-derived neurotrophic factor (BDNF) acting through the tropomyosin-related kinase receptor B

260 MAC1 acts through the 5' untranslated region of psaC transcri

261 signal for plant growth and development that acts through the AUXIN RESPONSE FACTOR (ARF) transcripti

262 ity that ARF4-dependent polarized exocytosis acts through the basal body-ciliary complex to spatially

263 em cell factor (SCF) is a growth factor that acts through the c-Kit receptor tyrosine kinase to elici

264 by inhibiting the degradation mechanism that acts through the C-terminus of ACS5.

265 oxia elevates expression of Cav1, which then acts through the calcium-binding protein S100P to promot

266 ta-that the pH change in the cellular milieu acts through the deprotonation of glutamate 8 to release

267 surface requires an S-phase checkpoint that acts through the DNA damage response (DDR) pathway, invo

268 her studies indicate that hedgehog signaling acts through the Foxf1/2 transcription factors to specif

269 critical cardiac developmental peptide that acts through the G-protein-coupled apelin receptor, desp

270 ify CASTOR1 as a direct arginine sensor that acts through the GATOR2 complex to regulate mTORC1.

271 ry factor Enabled, and we find that Abl also acts through the GEF Trio to stimulate the signaling act

272 ical assays, we find that resveratrol indeed acts through the ICRF-187 binding locus, but that it inh

273 data indicate that light at moderate levels acts through the plant's nuclear-localized sensory-photo

274 Our results support a model in which LsERF1 acts through the promotion of gibberellin biosynthesis t

275 eptide CLAVATA3/ESR-RELATED40 (CLE40), which acts through the receptor kinases ARABIDOPSIS CRINKLY4 (

276 It acts through the reduction and the inhibition of parasit

277 We identified a sizer protein, CDKG1, that acts through the retinoblastoma (RB) tumor suppressor pa

278 and various DDX1 mutants, we show that DDX1 acts through the RRE RNA to specifically accelerate the

279 However, whereas BEC-1/BECN1/Beclin1 acts through the transcriptional regulator SKN-1/Nrf1, A

280 such as prednisone or deflazacort thought to act through their immunosuppressive properties.

281 early life survival such as maternal age may act through their influence on infant body mass.

282 -coding regions of the genome and thought to act through their regulatory roles.

283 C5a and C3a suppress IFN-beta production by acting through their respective receptors, because no in

284 Acting through these diverse signaling pathways, bile ac

285 ds to the promoters of EDS1 and JAZ5, likely acting through these genes to affect SA- and JA-signalin

286 y components and major upstream signals that act through this pathway to influence embryogenesis.

287 o a key susceptibility gene for GD, probably acting through thymic-dependent central tolerance.

288 RNP-6 acts through TIR-1/PMK-1/MAPK signaling to modulate immu

289 We conclude, BLP acting through TLR2, is a potent inducer of inflammation

290 ted with TLR4 inhibitor, indicating that MfP acts through TLR4.

291 iated with the detrimental effects of solTNF acting through TNFR1, while tmTNF promotes repair and re

292 Microbial stimuli, acting through Toll-like receptors, induced transforming

293 on our data, we propose a model in which TH acting through TRalpha1 and TRbeta1, respectively, fine

294 They act through two dissociable signaling pathways: the exch

295 C5a acts through two C5a receptors, C5aR1 (C5aR, CD88) and C

296 Platelet-derived growth factor (PDGF) acts through two conserved receptor tyrosine kinases: PD

297 These effects were dependent on IL-4 acting through type 2 IL-4 receptors on neutrophils.

298 enhancing release of BDNF that subsequently acts through tyrosine receptor kinase B (TrkB) receptor

299 iven tissue overgrowth and indicate that Ctp acts through Yorkie to control bantam (ban) and diap1 tr

300 that promotes the integrity of the Z ring by acting through ZapB and raises the possibility of the ex