ライフサイエンスコーパス: actinomycetemcomitans

1 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans).

2 AZM or 16 mug/mL AMX (equipotent against A. actinomycetemcomitans).

3 -producing organisms such as Aggregatibacter actinomycetemcomitans.

4 ation between smoking and the presence of A. actinomycetemcomitans.

5 ormation, and periodontitis severity than A. actinomycetemcomitans.

6 is required for optimal biofilm growth by A. actinomycetemcomitans.

7 i, Streptococcus mutans, and Aggregatibacter actinomycetemcomitans.

8 and leukotoxin A (LtxA) from Aggregatibacter actinomycetemcomitans.

9 = 6 mm, BOP, and ABL, except Aggregatibacter actinomycetemcomitans.

10 and 41 participants who were negative for A. actinomycetemcomitans.

11 y those testing positive for Aggregatibacter actinomycetemcomitans.

12 tis and/or the individual colonization of A. actinomycetemcomitans.

13 both wild-type and morC mutant strains of A. actinomycetemcomitans.

14 d significant phagocytic activity against A. actinomycetemcomitans.

15 ely Streptococcus mutans and Aggregatibacter actinomycetemcomitans.

16 eased colonization risk with Aggregatibacter actinomycetemcomitans.

17 ted from the oral bacterium, Aggregatibacter actinomycetemcomitans.

18 equence of a serotype b non-JP2 strain of A. actinomycetemcomitans.

19 ve implants, per group, with Aggregatibacter actinomycetemcomitans.

20 may be capable of phosphorylating AI-2 in A. actinomycetemcomitans.

21 is required for optimal biofilm growth by A. actinomycetemcomitans.

22 Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans.

23 EmaA on the LPS biosynthetic machinery in A. actinomycetemcomitans.

24 Ns cope with an overwhelming infection by A. actinomycetemcomitans.

25 P for detection frequency of key pathogen A. actinomycetemcomitans.

26 re genes distinguished A. aphrophilus and A. actinomycetemcomitans.

27 ystem for AZM that may enhance killing of A. actinomycetemcomitans.

28 l levels and prediabetes were as follows: A. actinomycetemcomitans, 2.48 (1.34, 4.58), P = 0.004; P.

29 The majority of the individuals carrying A. actinomycetemcomitans (80.1%) (P <0.001) and of the peri

30 th altered outer membrane morphology make A. actinomycetemcomitans a model organism for examining mem

31 creted by the oral bacterium Aggregatibacter actinomycetemcomitans A. actinomycetemcomitans is an ora

32 (P.i.), and 5.8 x 10(4) for Aggregatibacter actinomycetemcomitans (A.a.).

33 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans), a capnophilic facultative anaero

34 Aggregatibacter actinomycetemcomitans, a periodontal pathogen, synthesiz

35 tx is a marker for presence of leukotoxic A. actinomycetemcomitans, a presence that may modify the di

36 terial complexes, and "high" Aggregatibacter actinomycetemcomitans (Aa) colonization.

37 ammatory response induced by Aggregatibacter actinomycetemcomitans (Aa) in human coronary artery endo

38 bacterial biofilm of Sg and Aggregatibacter actinomycetemcomitans (Aa) in terms of hydrogen peroxide

39 disease (PD) associated with Aggregatibacter actinomycetemcomitans (Aa) infection.

40 The oral pathogen Aggregatibacter actinomycetemcomitans (Aa) resides in infection sites wi

41 Heat-killed Aggregatibacter actinomycetemcomitans (Aa) was injected 3x/week (4 weeks

42 Aggregatibacter actinomycetemcomitans (Aa) was the only species found to

43 rphyromonas gingivalis (Pg), Aggregatibacter actinomycetemcomitans (Aa), Fusobacterium nucleatum (Fn)

44 usobacterium nucleatum (Fn), Aggregatibacter actinomycetemcomitans (Aa), Porphyromonas gingivalis (Pg

45 rphyromonas gingivalis (Pg), Aggregatibacter actinomycetemcomitans (Aa), Tannerella forsythia (Tf), a

46 e, and alveolar bone loss in Aggregatibacter actinomycetemcomitans (Aa)-inoculated Fawn Hooded Hypert

47 D superfamily of genes and that TadZ from A. actinomycetemcomitans (AaTadZ) forms a polar focus in th

48 A. actinomycetemcomitans activates the p38 mitogen-activate

49 ere the three-organism consortium (versus A. actinomycetemcomitans alone) was detected, the specifici

50 ences in serum IgG levels to Aggregatibacter actinomycetemcomitans among the four diagnostic categori

51 Aggregatibacter actinomycetemcomitans, an oral pathogen representative o

52 and in vitro colonization by Aggregatibacter actinomycetemcomitans, an organism highly associated wit

53 as a direct transcriptional activator in A. actinomycetemcomitans; an mlc deletion mutant reduces le

54 umina MiSeq platform was performed for 31 A. actinomycetemcomitans and 2 A. aphrophilus strains.

55 ing 41 participants who were positive for A. actinomycetemcomitans and 41 participants who were negat

56 cin-loaded PMNs killed significantly more A. actinomycetemcomitans and achieved shorter half-times fo

57 A. actinomycetemcomitans and AL were frequently found in Gh

58 e strongest predictor of both presence of A. actinomycetemcomitans and AL.

59 wild-type mice were orally infected with A. actinomycetemcomitans and analyzed for bacterial coloniz

60 a are reported concerning the presence of A. actinomycetemcomitans and attachment loss (AL) in sub-Sa

61 several bacteria, including Aggregatibacter actinomycetemcomitans and Caulobacter crescentus.

62 lacZ transcriptional fusions in wild-type A. actinomycetemcomitans and DeltaihfA and DeltaihfB mutant

63 ted on days 0, 2, and 4 with Aggregatibacter actinomycetemcomitans and divided into groups (n = 5) th

64 ssion models, subgingival colonization of A. actinomycetemcomitans and F. nucleatum/periodonticum was

65 chain reaction, and culture detection of A. actinomycetemcomitans and microcomputed tomography quant

66 omitans in BL and (ii) the association of A. actinomycetemcomitans and other microbes in their relati

67 e and promoted a significant reduction of A. actinomycetemcomitans and P. gingivalis counts (P > 0.05

68 gival plaque samples for the detection of A. actinomycetemcomitans and P. gingivalis in each of the 1

69 A. actinomycetemcomitans and P. gingivalis quantities in sa

70 The counts of A. actinomycetemcomitans and P. gingivalis were significant

71 n the groups were seen after 3 months for A. actinomycetemcomitans and P. gingivalis, and after 12 mo

72 Aggregatibacter actinomycetemcomitans and Parvimonas micra (Pm) showed a

73 study, the aim is to measure Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis amoun

74 Different serotypes of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis have

75 tion in periodontopathogenic Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis viabi

76 inst the periodontopathogens Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis with

77 3 and PCT5 were dominated by Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis, resp

78 A. actinomycetemcomitans and Staphylococcus species do not

79 The prevalence of Aggregatibacter actinomycetemcomitans and Staphylococcus species was ver

80 vides a comprehensive genomic analysis of A. actinomycetemcomitans and the closely related nonpathoge

81 frequency of JP2 and non-JP2 genotypes of A. actinomycetemcomitans and the presence of AL in Ghanaian

82 thensis, Treponema denticola, Actinobacillus actinomycetemcomitans) and dental caries (Streptococcus

83 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans) and Porphyromonas gingivalis in p

84 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans), and Porphyromonas gingivalis.

85 of the periodontal pathogen Aggregatibacter actinomycetemcomitans, and a commensal Streptococcus par

86 trains antagonistic toward P. gingivalis, A. actinomycetemcomitans, and F. nucleatum was found to be

87 of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum were

88 a: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum.

89 , GI, total bacterial load, T. forsythia, A. actinomycetemcomitans, and GCF volume.

90 idence of the association of Aggregatibacter actinomycetemcomitans, and its highly leukotoxic JP2 gen

91 s of Parvimonas micra, Filifactor alocis, A. actinomycetemcomitans, and Peptostreptococcus sp. human

92 icantly greater amounts of P. gingivalis, A. actinomycetemcomitans, and T. forsythia than never-smoke

93 Streptococcus, Actinomyces, A. actinomycetemcomitans, and total anaerobic counts were e

94 valis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, and total bacterial load were det

95 rulence of the oral pathogen Aggregatibacter actinomycetemcomitans, and we previously showed that lsr

96 of S. gordonii with P. gingivalis or with A. actinomycetemcomitans are more pathogenic in animal mode

97 Eighty participants with Aggregatibacter actinomycetemcomitans-associated moderate to advanced pe

98 The carrier status of A. actinomycetemcomitans at the individual level was determ

99 PRP interfered with P. gingivalis and A. actinomycetemcomitans attachment and enhanced exfoliatio

100 and Mk2(-/-) mice were treated with live A. actinomycetemcomitans bacteria at the midsagittal suture

101 A. actinomycetemcomitans binding to SHA was irreversible an

102 The trimeric adhesin EmaA of A. actinomycetemcomitans binds to collagen and is modified

103 sults describe a novel animal model where A. actinomycetemcomitans biofilm was established in vitro o

104 Viable A. actinomycetemcomitans biofilm was successfully establish

105 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans)-biofilm colonizing titanium impla

106 s aureus, S. epidermidis and Aggregatibacter actinomycetemcomitans, but not by A. pleuropneumoniae se

107 LtxA acts as a virulence factor for A. actinomycetemcomitans by binding to the beta(2) integrin

108 an AMX at enhancing phagocytic killing of A. actinomycetemcomitans by neutrophils.

109 clustered into eight groups: Aggregatibacter actinomycetemcomitans, Campylobacter spp., Capnocytophag

110 Gram-negative Aggregatibacter actinomycetemcomitans can be distinguished (based on the

111 Aggregatibacter aphrophilus, Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenell

112 rom the periodontal pathogen Aggregatibacter actinomycetemcomitans causes extensive damage to gingiva

113 Our previous studies with Actinobacillus actinomycetemcomitans Cdt demonstrate not only that the

114 A. actinomycetemcomitans cells rapidly lost viability at ev

115 A. actinomycetemcomitans cells were highly sensitive to eve

116 nctions of the oral pathogen Aggregatibacter actinomycetemcomitans change during pairwise coinfection

117 th differing constellations of genes, the A. actinomycetemcomitans clades may have evolved distinct a

118 ormation, both of which are important for A. actinomycetemcomitans colonization and subsequent infect

119 bility of mast cells against Aggregatibacter actinomycetemcomitans compared with macrophages is evalu

120 es following exposure to the Aggregatibacter actinomycetemcomitans cytolethal distending toxin (Cdt)

121 In vitro, A. actinomycetemcomitans desorbed from BECs and transferred

122 Sixteen of 63 subjects with A. actinomycetemcomitans developed BL (the other 47 subject

123 pport, and pathogens such as Aggregatibacter actinomycetemcomitans display resource partitioning to f

124 The periodontal pathogen Aggregatibacter actinomycetemcomitans displays two proteinaceous surface

125 and nine small regulatory RNAs (sRNAs) in A. actinomycetemcomitans during planktonic and biofilm grow

126 Prevalence and levels of Aggregatibacter actinomycetemcomitans, Eikenella corrodens, and Fusobact

127 ast cells and macrophages, incubated with A. actinomycetemcomitans, either opsonized or not, with dif

128 Thirteen studies found Aggregatibacter actinomycetemcomitans elevated in AgP in comparison with

129 at a low concentration range regulated by A. actinomycetemcomitans enhanced the biofilm formation.

130 Ts from Haemophilus ducreyi, Aggregatibacter actinomycetemcomitans, Escherichia coli, and Campylobact

131 Aggregatibacter actinomycetemcomitans establishes a tenacious biofilm th

132 um implants were inoculated in vitro with A. actinomycetemcomitans, establishing a biofilm for 1 to 3

133 In this environment, A. actinomycetemcomitans faces numerous host- and microbe-d

134 se H and fumarate reductase are important A. actinomycetemcomitans fitness determinants in vivo.

135 points over 7 h to assess the transfer of A. actinomycetemcomitans from teeth or BECs to HA.

136 defined medium, approximately 14% of the A. actinomycetemcomitans genes were differentially regulate

137 sequencing, we discovered that 33% of the A. actinomycetemcomitans genome is required for coinfection

138 genes accounted for 14.1% to 23.2% of the A. actinomycetemcomitans genomes, with a majority belonging

139 developed BL (the other 47 subjects with A. actinomycetemcomitans had no BL).

140 Patients who were positive for A. actinomycetemcomitans had no specific benefit from amoxi

141 A. actinomycetemcomitans IHFalpha and IHFbeta were expresse

142 trongest association with the presence of A. actinomycetemcomitans in all subjects and in the subgrou

143 every 6 months to assess (i) the role of A. actinomycetemcomitans in BL and (ii) the association of

144 ient mutant KDP128, and live Aggregatibacter actinomycetemcomitans In contrast, infection of miR-155

145 JP2 and non-JP2 genotypes of Aggregatibacter actinomycetemcomitans in the Ghanaian adolescent populat

146 a, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans in the subgingival biofilm of indi

147 One patient was positive for A. actinomycetemcomitans in the three types of samples.

148 ir periodontal status and the presence of A. actinomycetemcomitans in their oral cavity.

149 ttenuated by the presence of Aggregatibacter actinomycetemcomitans in tri-species biofilms.

150 ight into metabolic pathways required for A. actinomycetemcomitans in vivo fitness.

151 tially regulated in vivo, suggesting that A. actinomycetemcomitans in vivo metabolism is distinct fro

152 Growth of attached A. actinomycetemcomitans in vivo was enhanced by lactate av

153 f the opportunistic pathogen Aggregatibacter actinomycetemcomitans in vivo.

154 ipopolysaccharide (LPS) from Aggregatibacter actinomycetemcomitans in wild-type (WT) and SP/ON-null C

155 , T. denticola, and T. forsythia, but not A. actinomycetemcomitans, in subgingival plaque.

156 e antibodies induced by P. gingivalis and A. actinomycetemcomitans include anti-phosphorylcholine (al

157 egative periodontal pathogen Aggregatibacter actinomycetemcomitans include serotype a, b, and c strai

158 Oral infection with A. actinomycetemcomitans increased LF levels in periodontal

159 Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans, increased GCF-IL-1beta levels, an

160 Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans induce remarkable IgG responses th

161 d LFKO(-/-) mice were more susceptible to A. actinomycetemcomitans-induced alveolar bone loss, with d

162 regulation of chemokine signaling during A. actinomycetemcomitans-induced inflammation and bone loss

163 Aggregatibacter actinomycetemcomitans-induced localized aggressive perio

164 tudy is to evaluate the role of LF during A. actinomycetemcomitans-induced periodontitis.

165 xide synthase (iNOS) in a murine model of A. actinomycetemcomitans-induced periodontitis.

166 and nitrogen intermediates in periodontal A. actinomycetemcomitans infection and progression to perio

167 hat NADPH oxidase is important to control A. actinomycetemcomitans infection in the murine oral cavit

168 by the periodontal pathogen Aggregatibacter actinomycetemcomitans, inhibits the proliferation of cul

169 the Gram-negative bacterium Aggregatibacter actinomycetemcomitans is a fibrillar collagen adhesin be

170 Aggregatibacter actinomycetemcomitans is a Gram-negative commensal bacte

171 eukotoxin (Ltx) expressed by Aggregatibacter actinomycetemcomitans is a powerful exotoxin, which can

172 Gram-negative facultative Aggregatibacter actinomycetemcomitans is an oral pathogen associated wit

173 ium Aggregatibacter actinomycetemcomitans A. actinomycetemcomitans is an oral pathogen strongly assoc

174 Aggregatibacter actinomycetemcomitans is associated with aggressive peri

175 Aggregatibacter actinomycetemcomitans is associated with aggressive peri

176 nfirmatory evidence that the detection of A. actinomycetemcomitans is associated with IL-6 genetic fa

177 by the periodontal pathogen Aggregatibacter actinomycetemcomitans is dependent upon autoinducer-2 (A

178 Aggregatibacter actinomycetemcomitans is hypothesized to colonize throug

179 Aggregatibacter actinomycetemcomitans is implicated in localized aggress

180 e we show that the expression of QseBC in A. actinomycetemcomitans is induced by AI-2 and that induct

181 Aggregatibacter actinomycetemcomitans is the main periodontopathogen of

182 inhibit biofilm formation by Aggregatibacter actinomycetemcomitans, Klebsiella pneumoniae, Staphyloco

183 Variants in A. actinomycetemcomitans leukotoxin (ltx) were created, lab

184 Aggregatibacter actinomycetemcomitans leukotoxin (LtxA) is a major virul

185 a, Tannerella forsythia, and Aggregatibacter actinomycetemcomitans levels in subgingival plaque were

186 ans outer membrane protein 29 (Omp29) and A. actinomycetemcomitans lipopolysaccharide (LPS) were inje

187 by periodontal injection of Aggregatibacter actinomycetemcomitans lipopolysaccharide (LPS), while si

188 and preclinical models using Aggregatibacter actinomycetemcomitans lipopolysaccharide-induced alveola

189 by periodontal injection of Aggregatibacter actinomycetemcomitans LPS.

190 or alternatively that the start codon of A. actinomycetemcomitans lsrA has been incorrectly annotate

191 e previously showed that the Aggregatibacter actinomycetemcomitans lsrACDBFG and lsrRK operons are re

192 vels of systemic immunoreactivity against A. actinomycetemcomitans Ltx are associated with decreased

193 f murine mast cells as phagocytes against A. actinomycetemcomitans, mainly in the absence of opsoniza

194 A. actinomycetemcomitans migrated from BECs to HA in vivo a

195 HA in vivo and to SHA in vitro; however, A. actinomycetemcomitans movement from teeth and SHA to BEC

196 Detection frequency of Aggregatibacter actinomycetemcomitans (MT4/MSP: 42%/36%), Porphyromonas

197 Seventy-one A. actinomycetemcomitans-negative and 63 A. actinomycetemco

198 itans positive for teeth only, and 3 were A. actinomycetemcomitans-negative controls) had two mandibu

199 No A. actinomycetemcomitans-negative subjects developed BL.

200 All 5 subjects with A. actinomycetemcomitans on BECs showed transfer of A. acti

201 itans to HA was not seen in subjects with A. actinomycetemcomitans on teeth only.

202 Cs stimulated with different serotypes of A. actinomycetemcomitans or P. gingivalis is TLR2 or TLR4 d

203 Cs stimulated with different serotypes of A. actinomycetemcomitans or P. gingivalis is Toll-like rece

204 f infection (MOI) of 10(2) with different A. actinomycetemcomitans or P. gingivalis serotypes in the

205 en DCs were stimulated with serotype b of A. actinomycetemcomitans or serotype K1 of P. gingivalis, h

206 in relation to increasing colonization of A. actinomycetemcomitans (OR = 1.36 for one standard deviat

207 Aggregatibacter actinomycetemcomitans outer membrane protein 29 (Omp29)

208 The counts of A. actinomycetemcomitans (P <0.001), P. gingivalis (P = 0.0

209 etween smoking status and the presence of A. actinomycetemcomitans (P <0.001).

210 sponse to the challenge by two strains of A. actinomycetemcomitans (P = 0.018 and P = 0.046).

211 ctively 60%, 62%, and 40% of subjects had A. actinomycetemcomitans, P. gingivalis, and both bacteria

212 All targeted periodontal pathogens (A. actinomycetemcomitans, P. gingivalis, T. forsythia, or C

213 A. actinomycetemcomitans, P. gingivalis, T. forsythia, P. i

214 signaling in chemokine regulation during A. actinomycetemcomitans pathogenesis.

215 At 5 weeks after infection, A. actinomycetemcomitans persisted at significantly higher

216 nomycetemcomitans (previously Actinobacillus actinomycetemcomitans), Porphyromonas gingivalis, and Pr

217 esence and quantification of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis (Pg), Ta

218 ntify periodontal pathogens (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Campylo

219 for quantitative analysis of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Prevote

220 titative bacterial counts of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

221 esence and quantification of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

222 years, periodontal bacteria (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

223 nce of Campylobacter rectus, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

224 The levels of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

225 olymerase chain reaction for Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

226 a), and cultivable bacteria (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

227 ue samples were analyzed for Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

228 determined total bacterial, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Tannere

229 For Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Trepone

230 essed at baseline, including Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Trepone

231 Thirteen volunteers (5 were A. actinomycetemcomitans positive for buccal epithelial cel

232 epithelial cells [BECs] and teeth, 5 were A. actinomycetemcomitans positive for teeth only, and 3 wer

233 e following factors (interaction effect): A. actinomycetemcomitans-positive or -negative at baseline,

234 Being A. actinomycetemcomitans-positive or -negative did not chan

235 A. actinomycetemcomitans-negative and 63 A. actinomycetemcomitans-positive periodontally healthy sub

236 On a subject level, pooled data from A. actinomycetemcomitans-positive subjects who remained hea

237 eptococcus and Actinomyces species, while A. actinomycetemcomitans-positive subjects with BL had high

238 o study the host response to Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

239 inhibitory concentration for Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

240 nhance their ability to kill Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

241 Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

242 esponse to Escherichia coli, Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

243 factors on the detection of Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinom

244 of Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Eikenella

245 Aggregatibacter actinomycetemcomitans produces a repeats-in-toxin (RTX)

246 We report that A. actinomycetemcomitans promoted biofilm formation of S. p

247 These results demonstrate that A. actinomycetemcomitans promotes the S. parasanguinis biof

248 he Escherichia coli LsrB and Aggregatibacter actinomycetemcomitans RbsB proteins that bind AI-2.

249 ions, predominately with nonoral species, A. actinomycetemcomitans required 50 fewer genes than in mo

250 Aggregatibacter actinomycetemcomitans resists killing by neutrophils and

251 While it is clear that A. actinomycetemcomitans responds to precise cues that allo

252 ling of S. parasanguinis co-cultured with A. actinomycetemcomitans revealed a significant decrease in

253 e conclude that detecting the presence of A. actinomycetemcomitans, S. parasanguinis, and F. alocis t

254 A. actinomycetemcomitans secretes a protein toxin, leukotox

255 ociated with increased systemic levels of A. actinomycetemcomitans-specific immunoglobulins and incre

256 uggest that antibody to RANKL can inhibit A. actinomycetemcomitans-specific T cell-induced periodonta

257 However, in the absence of fimbriae, A. actinomycetemcomitans still retains the potential to for

258 constructed a hyper-leukotoxin producing A. actinomycetemcomitans strain and identified a terminator

259 We report the first genome sequence of an A. actinomycetemcomitans strain isolated from an Old World

260 Opsonized A. actinomycetemcomitans strain Y4 was incubated with the i

261 A. actinomycetemcomitans strains can produce high or low le

262 A. actinomycetemcomitans strains expressing EmaA with the i

263 The genetic heterogeneity among A. actinomycetemcomitans strains has been long recognized.

264 Indigenous and inoculated A. actinomycetemcomitans strains that attached were associa

265 At vulnerable sites, A. actinomycetemcomitans, Streptococcus parasanguinis, and

266 human oropharyngeal pathogen Aggregatibacter actinomycetemcomitans synthesizes multiple adhesins, inc

267 s (Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia, or Prevotel

268 from the separation of A. aphrophilus and A. actinomycetemcomitans through gain and loss of genes and

269 Transfer of A. actinomycetemcomitans to HA was not seen in subjects wit

270 ycetemcomitans on BECs showed transfer of A. actinomycetemcomitans to HA.

271 BECs are a likely reservoir for A. actinomycetemcomitans tooth colonization.

272 We identified 691 A. actinomycetemcomitans transcriptional start sites and 21

273 -/-) mice compared to Mk2(+/+) mice after A. actinomycetemcomitans treatment.

274 ive periodontitis-associated Aggregatibacter actinomycetemcomitans triggered a type I IFN response fo

275 nctionally active in Escherichia coli and A. actinomycetemcomitans using truncated PhoA and Aae chime

276 ork analysis, we assessed colonization of A. actinomycetemcomitans variants and ascertained microbial

277 lity to grow in biofilms is essential for A. actinomycetemcomitans virulence, strains that were defic

278 The overall carrier rate of A. actinomycetemcomitans was 54.4%, and the highly leukotox

279 ytic ability of murine mast cells against A. actinomycetemcomitans was confirmed.

280 The presence of A. actinomycetemcomitans was demonstrated in vascular, bloo

281 A. actinomycetemcomitans was detected by polymerase chain r

282 Fusobacterium nucleatum, and Aggregatibacter actinomycetemcomitans was examined using the agar overla

283 A. actinomycetemcomitans was found at 0.13% of the total fl

284 ia, Treponema denticola, and Aggregatibacter actinomycetemcomitans was identified by polymerase chain

285 A. actinomycetemcomitans was more abundant when coinfected

286 A. actinomycetemcomitans was significantly associated with

287 Aggregatibacter actinomycetemcomitans was significantly decreased in FMD

288 rom the periodontal pathogen Aggregatibacter actinomycetemcomitans, was conjugated to an anti-human C

289 gene, encoding a cytoplasmic catalase in A. actinomycetemcomitans, was responsible for the reduction

290 pression and influences biofilm growth of A. actinomycetemcomitans, we first defined the promoters fo

291 Although no ncRNAs have been reported in A. actinomycetemcomitans, we propose that they are likely i

292 saliva and serum IgG against Aggregatibacter actinomycetemcomitans were negatively correlated with PL

293 Lower levels of Aggregatibacter actinomycetemcomitans were observed in the PDT and SRP p

294 reptococcus constellatus, or Aggregatibacter actinomycetemcomitans, were resistant in vitro to doxycy

295 Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans, were similarly reduced.

296 nst the periodontal pathogen Aggregatibacter actinomycetemcomitans when the bacteria were added to th

297 letion of 530 bps in a primate isolate of A. actinomycetemcomitans, which produced leukotoxin equival

298 desorption, transfer, and reattachment of A. actinomycetemcomitans wild-type and mutant strains to BE

299 These results suggested an association of A. actinomycetemcomitans with AgP, but neither this species

300 is to determine if patients positive for A. actinomycetemcomitans with moderate to advanced periodon

301 These associations provide A. actinomycetemcomitans with the constituents required for