ライフサイエンスコーパス: activator

1 treatment with tPA (tissue-type plasminogen activator).

2 on the presence of a strong transcriptional activator.

3 ein ligands, such as tissue-type plasminogen activator.

4 eated with various doses of poly I:C, a TLR3 activator.

5 CXCL1, an important neutrophil recruiter and activator.

6 ene expression, for which LuxR is a required activator.

7 2)-macroglobulin and tissue-type plasminogen activator.

8 revealing UMI-77 as an unexpected mitophagy activator.

9 n lysine deacetylase SIRT1 to small-molecule activators.

10 pression of genes, by resisting strong trans activators.

11 motifs recognized by strong transcriptional activators.

12 ption machinery, mimicking archetypal acidic activators.

13 processing GLI proteins into transcriptional activators.

14 hat might be used to identify additional WDD activators.

15 rized canonical sigma704-bound transcription activators.

16 can be enhanced by allosteric small-molecule activators.

17 r in complex with PA28alphabeta or PA28gamma activators.

18 exons relative to introns and bind splicing activators.

19 ating the need for exogenous transcriptional activators.

20 ponse Regulator family of cytokinin response activators.

21 haracterized sigmaA4-dependent transcription activators.

22 overcome the drug resistance of ferroptosis activators.

23 Finally, we identified NF-kappaB activator 1 (Act1), p38 mitogen-activated protein kinase

24 double-stranded RNA-dependent protein kinase activator A), the product of another gene causing monoge

25 d tissue-type and urokinase-type plasminogen activators, a relatively decreased plasminogen activator

26 fferent behaviours for different allomorphic activators, allomorphy allows an organism to maximise it

27 rmed Orb2 from a translation repressor to an activator and "seed" for further translationally active

28 1 is an in bona fide VAR1 mRNA translational activator and additionally interacts with newly synthesi

29 so activates a repressor, which inhibits the activator and diffuses to neighboring cells.

30 tric oxide, endothelin-1, tissue plasminogen activator and plasminogen activator inhibitor-1, was dep

31 pression mechanisms by direct interaction of activator and repressor WOX genes may be required for ce

32 3K27ac enrichment in limb buds devoid of GLI activator and repressor, indicating that their activity

33 by specific contacts between the disordered activator and the Med25 interface, which is facilitated

34 TFL) composed of CLOCK-BMAL1 transcriptional activators and CRY-PER transcriptional repressors.

35 We study the roles of activators and deactivators, two core components of osci

36 lasticity plays in recognition of disordered activators and indicate that molecular recognition model

37 However, the molecular activators and inhibitors fully fitting this versatile m

38 ression of direct and specific upstream Rap1 activators and inhibitors.

39 Although changes in the state of activators and repressors has been characterized, how th

40 feedback loops in the biochemical network of activators and repressors of cytoskeleton dynamics have

41 els, where Rgg2 proteins are transcriptional activators and Rgg3 proteins are transcriptional repress

42 o traditional NO generators, a number of sGC activators and stimulators are currently in clinical tri

43 Treatment with CHIR99021, a Wnt activator, and DAPT, a Notch inhibitor, leads to further

44 gnetic field (AMF) similar to the neutrophil activator, and the loaded CPO within protective peptides

45 repression of the key ToxR regulon virulence activator aphB, and ompR overexpression in wild-type cel

46 evalent point mutations in a transcriptional activator (Aro80) that is responsible for regulating the

47 mediator expression induced by TLR2 and TLR4 activators as well as NFkappaB activation in a macrophag

48 arasites were treated with the demethylation activator ascorbic acid.

49 rom efforts that characterize their upstream activators, assembly of signaling complexes, and activat

50 ts and proceed in the presence of a fluoride activator at 80 degrees C.

51 tional small molecule linking the KEAP1-Nrf2 activator bardoxolone to a BRD4 inhibitor JQ1.

52 the regulatory dynamics of hunchback by the activator Bicoid and the pioneer-like transcription fact

53 uctose 1,6-bisphosphate (FBP), an allosteric activator, binding site, impacting the interaction with

54 This class of activators binds IRE1 in the kinase front pocket, leadin

55 longer DNA dwell times of the activator; the activator-bound gene may not readily turn off again.

56 is thaliana Calmodulin-binding Transcription Activator (CAMTA) transcription factors CAMTA1, CAMTA2,

57 rons, are inert to hyperoxia and other TRPA1 activators (carbon dioxide, electrophiles, and oxidants)

58 Addition of the Wnt/beta-catenin activator CHIR99021 reduced wound closure in the iAEC2 c

59 n of the activator-DNA complex or decreasing activator concentration.

60 by APC-Cdh1-mediated proteolysis of the Cdk1 activator, cyclin B1, secondary to increased Cdc14B-depe

61 ncreasing the energy for dissociation of the activator-DNA complex or decreasing activator concentrat

62 We show that kinetic proofreading of activator-DNA recognition-insertion of an energy-dissipa

63 Finally, we report new activator domains, including a divergent KRAB.

64 Accelerated tPA (tissue-type plasminogen activator) dosing regimens for ultrasound-facilitated, c

65 ivators that generate AMP, unlike allosteric activators, downregulated pMLC but only when combined wi

66 ning both as the translational repressor and activator during oocyte maturation.

67 lain AMPK switching from tumor suppressor to activator during tumor evolution.

68 to simultaneously release enzymes and their activators during biocatalysis with boosted activities.

69 mportantly, these E2F members, in particular activator E2F1 and repressors E2F7 and E2F8, form a feed

70 to both the Drosophila hobo element and the Activator element from maize.

71 -carboxamide ribonucleotide (AICAR), an AMPK activator, elicits a similar effect.

72 IV recombinant tissue plasminogen activator, endovascular treatment, IV albumin, or placeb

73 ia its interaction with the murein hydrolase activator, EnvC.

74 investigation revealed that the spontaneous activator/enzyme release and ion pumping enable enzymes

75 ate that small sequence variations within an activator family significantly redistribute the conforma

76 is caused by mutations in the RagC and RagD activator folliculin (FLCN) and is characterized by beni

77 s out a signature sequence and uses it as an activator for a "therapeutic" function, namely, the clea

78 unctions in the nucleus as a transcriptional activator for hundreds of genes.

79 C. albicans was a stronger activator for isolated human NK cells than C. glabrata.

80 9-polymeric NP containing tissue plasminogen activator for on-demand targeting of GPA receptors in vi

81 Consistent with this, expression of the CLN2 activator from the promoter of the WHI5 inhibitor, or vi

82 A strong activator (Gal4-VP16) greatly stimulated reversible bind

83 (AICAR), metformin, and a specific AMPKalpha activator (GSK621) attenuated ZIKV replication.

84 ough the stability of the transcriptional co-activator Hap4p.

85 Intravenous tissue plasminogen activator has been a cornerstone for treatment of acute

86 f SIRT6 activity, however, not many specific activators have been reported.

87 ly recognized property of the KCNQ2-specific activator ICA-069673 to identify assembly of heteromeric

88 fined to a potent and balanced FXR/PPARdelta activator in a computer-aided fashion.

89 determined the role of VSMC TFEB and a TFEB activator in AAA in vivo.

90 Therefore, GABPB1-AS1 functioned as a tumor activator in CC pathogenesis by binding to miR-519e-5p a

91 LUF7244 as a negative allosteric modulator/activator in combination with dofetilide corrected both

92 egulatory subunit, as a neuron-specific Drp1 activator in vivo Bbeta2 KO mice of both sexes display e

93 ibitors, GTP-RAS interaction inhibitors, and activators increasing GTPase activity of mutant RAS prot

94 ll-established that complexes of plasminogen-activator inhibitor 1 (PAI-1) with its target enzymes bi

95 sue plasminogen activator (tPA), plasminogen activator inhibitor 1 (PAI-1), and platelets.

96 tivators, a relatively decreased plasminogen activator inhibitor 1, and decreased levels of thrombin-

97 g (collagen-I, thrombospondin-I, plasminogen activator inhibitor, MMP1, 9, ADAMTS4, TIMP1); with GIM-

98 tic peptides, cardiac troponins, plasminogen activator inhibitor-1, D-dimer, fibrinogen, C-reactive p

99 tissue plasminogen activator and plasminogen activator inhibitor-1, was depressed by exposure to high

100 decrease VEGF by reducing PAI-1 (plasminogen activator inhibitor-1/SERPINE1) levels.

101 Thus, subtle changes in simple activator-inhibitor systems are likely essential contrib

102 ransporters NBCn1 and NBCn2 as well as their activators IRBIT and L-IRBIT in the regulation of the mT

103 trap line, in which the Gal4 transcriptional activator is integrated into the etv2 gene locus.

104 nversion of EZH2 from a gene repressor to an activator is unclear.

105 trolled by the PGC family of transcriptional activators is required for angiogenic responses.

106 of intravenous tPA (tissue-type plasminogen activator; IV tPA) in acute ischemic stroke patients wit

107 (Y954) located in the C-terminal lobe of the activator kinase domain was important to potentiate dime

108 0 expression by repressing a transcriptional activator, Kruppel-like factor-4 (KLF4).

109 d by the major replication and transcription activator KSHV protein called RTA.

110 te endosomal/lysosomal adaptor MAPK and mTOR activator (LAMTOR) complex as an important regulator of

111 iation between mTORC1 and its lysosome-borne activators, leading to mTORC1 hyperactivity.

112 f a highly reactive trans-cyclooctene as the activator leads to a complete cycloaddition reaction wit

113 DNA looping driven by designed transcription activator-like effector dimer (TALED) proteins.

114 programmable nucleases such as transcription activator-like effector nucleases (TALENs) and CRISPR-Ca

115 ed by zinc finger nucleases, transcriptional activator-like effector nucleases and, most recently, cl

116 forms: zinc-finger proteins, transcriptional activator-like effectors and clustered regularly intersp

117 I secreted effectors including transcription activator-like effectors, type II secretion systems, div

118 pression of the malR gene, which encodes the activator MalR.

119 nd that the combination of EGFR TKI and AMPK activator may be a potentially effective therapeutic str

120 eoxy-ATP (dATP) was used to study how myosin activators may affect soleus muscle relaxation.

121 These novel EPAC1 activators may therefore act as useful pharmacological t

122 iological conditions in the absence of other activators, membrane-anchored GTP-Rab5A provides strong,

123 n enzyme formulation using customized enzyme activators (metal ions) to directly construct metal-orga

124 Administering the AMPK activator metformin decreases epithelial progenitor prol

125 pithelial cells (AECs) with the novel TREK-1 activators ML335 and BL1249, and quantified physiologica

126 First, Hox genes function as activators, modifiers, and suppressors of trh expression

127 rotein-protein interactions, FBDD for enzyme activators, new screening technologies, and advances in

128 all affinity, and distal residues within the activator-not often considered as contributing to bindin

129 The BK activator, NS1619, rescued BK(G354S) cells but not siRNA

130 injury is believed to be an early and potent activator of a wound response.

131 a new function for TWD1 acting as a putative activator of ABCB-mediated auxin transport by cis-trans

132 ide in vivo evidence that CX3CL1 is a strong activator of adult neurogenesis, and that it reduces neu

133 the plant compound berberine (BBR), a potent activator of AMP-activated protein kinase (AMPK), can re

134 sferase 5 (PRMT5) functions as an epigenetic activator of AR transcription in CRPC, requiring coopera

135 Omecamtiv mecarbil (OM)-a novel activator of cardiac myosin-improves left ventricular sy

136 ency reversal by second mitochondria-derived activator of caspase (SMAC) mimetics was not affected by

137 E2FB is considered to be a transcriptional activator of cell cycle genes, but its function during d

138 Because Mycobacterium tuberculosis is an activator of cGAS-dependent cytosolic DNA sensing, we se

139 L-DOPA induced dyskinesia and is a critical activator of CINs via pERK and pS6.

140 ived from Gram-negative bacteria is a potent activator of circulating immune cells including neutroph

141 We find that PfAP2-G is a transcriptional activator of early gametocyte genes, and identify differ

142 licate PfAP2-G not only as a transcriptional activator of gametocyte genes, but also as a potential r

143 eficient K249Q mutant was even a more potent activator of gene expression; whereas, mutant OGG1 with

144 YAP is mainly described as a transcriptional activator of genes involved in cell proliferation and su

145 bHLH121 acts as a direct transcriptional activator of key genes involved in the Fe regulatory net

146 We show that NFAT5, an activator of macrophage pro-inflammatory responses, repr

147 ar whether Lis1 serves as an inhibitor or an activator of mammalian dynein motility.

148 bly, ICP27 also acts as a sequence-dependent activator of mRNA 3' processing for viral and a subset o

149 suppressed by constitutively active RagB, an activator of mTOR.

150 EF2C) transcription factor as a key upstream activator of Myoc whose gain of function significantly d

151 l death induced by nuclear MLKL was a potent activator of neutrophils, a cell type known to drive inf

152 periapical lesions points to a high receptor activator of NF-kappaB ligand/osteoprotegerin (RANKL/OPG

153 in [BSP], osteoprotegerin [OPG] and receptor activator of NF-KB ligand [RANKL]).

154 d many other pathogens, flagellin is a major activator of NLRC4 inflammasome-mediated macrophage pyro

155 ors of sulforaphane, the most active natural activator of Nrf2.

156 OPG), a secreted decoy receptor for receptor activator of nuclear factor B ligand (RANKL), plays an e

157 Serum receptor activator of nuclear factor kappa B ligand (RANKL) and i

158 osteoclast activator-related gene, receptor activator of nuclear factor kappa-B ligand, and osteobla

159 Using receptor activator of nuclear factor kappa-Beta ligand (RANKL) in

160 odel, where inducible expression of receptor-activator of nuclear factor kappa-Beta ligand (Rankl) le

161 of the pro-osteolytic factor termed receptor activator of nuclear factor kappaB ligand (RANKL), which

162 hypothesized that inhibition of the receptor activator of nuclear factor-kappaB (RANK) signaling path

163 Receptor activator of nuclear factor-kappaB ligand (RANKL) consti

164 hat the conserved FtsQLB complex is a direct activator of PG polymerization by the FtsWI synthase and

165 activating PKM2 via ML-265, a small molecule activator of PKM2, during acute outer retinal stress.

166 Akt inhibition or a specific small-molecule activator of PP2A (SMAP) efficiently attenuates HCC tumo

167 The p53 tumor suppressor protein is a potent activator of proliferative arrest and cell death.

168 roup of animals were fed dichloroacetate, an activator of pyruvate oxidation.

169 The MEKK1 protein is a pivotal kinase activator of responses to cellular stress.

170 e bPBP pedestal domain as the key allosteric activator of RodA both in vitro and in vivo, explaining

171 cell death, which is restricted by NPR1, an activator of systemic acquired resistance.

172 Forskolin, an activator of the cAMP/PKA pathway, increased wild-type K

173 Addition of the drug ISRIB, an activator of the eIF2 guanine nucleotide exchange factor

174 ous second messenger cyclic AMP (cAMP) is an activator of the Hypr GGDEF enzyme GacB from Myxococcus

175 Despite its established role as a potent activator of the immune system, NKG2D-driven regulation

176 ine interleukin-1beta (IL-1beta) is a potent activator of the inflammatory cascade following pathogen

177 e, we show that MITF is a lineage-restricted activator of the key lipogenic enzyme stearoyl-CoA desat

178 LPC 18:1 as a previously unknown endogenous activator of the ligand-gated calcium channels transient

179 ssing of prosaposin to saposin C, a critical activator of the lysosomal enzyme glucocerebrosidase (GC

180 gulator IRGM control TFEB, a transcriptional activator of the lysosomal system.

181 man foodborne pathogen Bacillus cereus is an activator of the NLRP3 inflammasome and pyroptosis.

182 ) oncogene functions as a transcriptional co-activator of the Wnt/beta-catenin pathway, which plays c

183 erleukin-4 (IL-4)- and signal transducer and activator of transciription-6 (STAT6)-dependent inhibiti

184 The Janus-kinase/signal transducer and activator of transcription (JAK/STAT) pathway regulates

185 us kinase signaling to signal transducer and activator of transcription (STAT) (ruxolitinib) or mitog

186 lated kinase (ERK) and signal transducer and activator of transcription (STAT) pathways.

187 ting the expression of signal transducer and activator of transcription 1 (STAT1), structural mainten

188 ed increased levels of signal transducer and activator of transcription 1 phosphorylation and a trans

189 tudy, we established a signal transducer and activator of transcription 2 (STAT2) knockout hamster mo

190 I interferon (IFN) and signal transducer and activator of transcription 2 (Stat2) signaling.

191 that leptin activates signal transducer and activator of transcription 3 (STAT3) and mitogen-activat

192 inhibit IL-6-activated signal transducer and activator of transcription 3 (STAT3) and subsequent indu

193 of Kdm6b We show that signal transducer and activator of transcription 3 (STAT3) is phosphorylated a

194 e transcription factor signal transducer and activator of transcription 3 (Stat3) plays important rol

195 The signal transducer and activator of transcription 3 (STAT3) protein is a master

196 ion is associated with signal transducer and activator of transcription 3 (STAT3)-specific gene signa

197 ates such as IL-6R and signal transducer and activator of transcription 3 (STAT3).

198 recruitment, including signal transducer and activator of transcription 3 and IL13, and downregulated

199 0(-12)) located within signal transducer and activator of transcription 4 gene was identified previou

200 in phosphorylation of signal transducer and activator of transcription 5, a downstream molecule of P

201 osine kinase 2 (TYK2), signal transducer and activator of transcription 5B (STAT5B), and STAT6 in p53

202 the biology of the JAK-signal transducer and activator of transcription pathway and the use of JAK in

203 eam Janus kinase (JAK)-signal transducer and activator of transcription pathway have emerged and are

204 triggered Janus kinase/signal transducer and activator of transcription signaling, boosted SARS-CoV-2

205 radigm from Wnt/beta-catenin primarily as an activator of transcription to a more nuanced view where

206 phorylated form of the signal transducer and activator of transcription-5 (pSTAT5) in adult male mice

207 s in PICF along with an increase in receptor activator of unclear factor kappa-B ligand, periostin, a

208 Downstream of KinB-AlgB, activators of alginate production AlgU (a sigma(E) ortho

209 Unedited Alu RNAs are potent activators of both IFN and NF-kappaB responses via the d

210 No activators of cGAMP signaling have yet been identified,

211 Here we extend the microbial activators of Lcn2 to mycoplasma and describe studies in

212 0 of Galpha(13) (encoded by GNA13) as potent activators of oncogenic signaling.

213 strategy can be applied not only to peptide activators of p53 for cancer therapy, but also to peptid

214 We identified peptides that are poor activators of PAR4-dependent calcium signaling but were

215 mechanistic basis for developing allosteric activators of PDE6 with therapeutic implications for hal

216 ytic AMPKalpha2 subunit and SIRT1, two known activators of PPARalpha.

217 r tissue revealed that miR-21 and miR-221, 2 activators of profibrotic and proliferative processes, i

218 -7 (let-7) microRNAs (miRNAs) are well-known activators of proliferative quiescence and terminal diff

219 locomotion during wakefulness, act as major activators of RIS.

220 e, TubZIP28 and TabZIP28 are transcriptional activators of starch synthesis first identified in wheat

221 lammatory mediator expression in response to activators of the pattern recognition receptors, toll-li

222 al a redundant function of XBP1s and ATF6 as activators of the viral life cycle, and an unexpected ro

223 inhibitory amino acids were also shown to be activators of TOR kinase.

224 This occurs via the recruitment of co-activator or co-repressor complexes that epigenetically

225 ally design the effector to be an allosteric activator or inhibitor is likely to be benefitted by kno

226 ther talin and kindlin-2, the major integrin activators, or filaminA, an integrin activity suppressor

227 otoperiodic flowering upstream of the floral activators OsMADS14 and Hd3a, through a mechanism remini

228 enzymes to sufficiently interact with their activators owing to the proximity effects, leading to a

229 d the effect of leptin, whereas a Src kinase activator peptide mimicked it.

230 lpP2 rings and also requires the presence of activator peptides, such as benzoyl-leucyl-leucine (Bz-L

231 hibition by the SUR2-specific K(ATP) channel activator pinacidil, which hyperpolarized both mouse and

232 eliminated harmful factors like plasminogen activator (Pla) and murine toxin from the OMVs.

233 in platelet stores of urokinase plasminogen activator (PLAU/uPA); subsequent plasmin-mediated degrad

234 ) and the serine protease tissue plasminogen activator, previously shown to potentiate NMDAR activity

235 Similarly, CEBPB-liver-enriched activator protein (LAP) isoform overexpression suppresse

236 We further linked JNK to RUNX1 through Activator Protein 1 (AP-1) and investigated the JNK-AP-1

237 restrict expression of JunB, a member of the activator protein 1 (AP-1) family of transcription facto

238 nt in mammals, shares functionally essential activator protein 1 (AP-1)-binding motifs, and responds

239 LPS transcriptionally activates YAP through activator protein 1 in macrophages/KCs.

240 Transcription Factor Activator Protein 2gamma (TFAP2C, AP-2gamma) governs lum

241 We used sdsB1 activator protein and SDS-responsive promoter of sdsA1 g

242 inhibited through direct binding of the anti-activator protein ExsD.

243 nsive changes following cryoinjury, and that activator protein-1 (AP-1) binding sites are the most hi

244 ntify a transcriptional program regulated by activator protein-1 (AP-1) complex, formed by c-Fos and

245 loproteinases driving the induction of c-Jun/activator protein-1.

246 he role of the soluble urokinase plasminogen activator receptor (suPAR) in focal segmental glomerulos

247 Soluble urokinase plasminogen activator receptor (suPAR) is a signaling glycoprotein t

248 monoclonal antibody to urokinase plasminogen activator receptor (uPAR) as a therapeutic strategy to a

249 05, targeting the urokinase-type plasminogen activator receptor (uPAR), and Gleason score in patients

250 nvolves the activation of peroxisome protein activator receptor gamma (PPARgamma), a nuclear receptor

251 lity of suPAR (soluble urokinase plasminogen activator receptor), a potential biomarker of pleural fl

252 mechanism governed by urokinase plasminogen activator receptor-associated protein (uPARAP or Endo180

253 increased mRNA expression of the osteoclast activator-related gene, receptor activator of nuclear fa

254 Ras homolog enriched in brain, an mTOR activator, rescued the effect of Slc7a5 knockdown on mTO

255 regulates both replication and transcription activator (RTA) activity and host hedgehog (hh) signalin

256 at the Salmonella anti-inflammatory response activator SarA (Stm2585, GogC, PagJ, SteE) activates the

257 B pathway by injecting the protein kinase B activator SC79 in Lgr4(-/-) mice can effectively reverse

258 oke who were treated with tissue plasminogen activator, shorter door-to-needle times were associated

259 rturbed autoregulation of canonical splicing activators (SRSF) and repressors (HNRNP).

260 with a conditional deletion of Orai1 (or its activator STIM1) in the brain.

261 or EPF1 exerts longer range effects than the activator Stomagen.

262 To date, most studies have focused on activators such as enhancers, but regions that repress g

263 NRF2 activators such as sulforaphane and bardoxolone methyl a

264 ke proteins convert nonactivator surfaces to activator surfaces by preventing the inactivation of the

265 er, combined treatment of EGFR TKI with AMPK activators synergistically increases EGFR TKI sensitivit

266 mice, thrombolysis using tissue-plasminogen activator (t-PA) reduced injury and improved motor defic

267 at the balance between T-box transcriptional activator, Tbx5, and T-box transcriptional repressor, Tb

268 otypes via transcription induction of AKT co-activator TCL1A by NANOG.

269 ng network only requires one self-activating activator that also activates a repressor, which inhibit

270 cipitation with HCF173, a psbA translational activator that is known to bind psbA mRNA.

271 ound screening identified a protein kinase c activator that promotes maturation of pre-alpha cells in

272 nly functions as an anthocyanin biosynthesis activator that specifically determines leaf marking form

273 al regulation is imparted by transcriptional activators that bind to specific DNA sequences from whic

274 age seems to be a common mechanism for NLRP3 activators that function through lysosomal damage.

275 Pharmacological AMPK activators that generate AMP, unlike allosteric activato

276 ctrophysiological assays, we found that this activator, the bromothiophene-substituted small molecule

277 energies imply longer DNA dwell times of the activator; the activator-bound gene may not readily turn

278 plain this puzzling activation using a novel activator, thorough kinetic investigation, and mutagenes

279 describes the use of a subtype-specific Kv7 activator to assess assembly of heteromeric KCNQ2/KCNQ3

280 nhancing binding of the E2F1 transcriptional activator to the EZH2 promoter.

281 xpression could cause an increasing ratio of activators to inhibitors with size, triggering cell-cycl

282 elective and selective kinase inhibitors and activators to test the effect of phosphorylation on Nav1

283 lus LUF7244, a K(v)11.1 allosteric modulator/activator, to rescue K(v)11.1 trafficking and produce fu

284 ATR activation requires the ATR activator, topoisomerase IIbeta-binding protein 1 (TopBP

285 The plasminogen activator tPA was lower in HA-NCI while neuroserpin, the

286 rothrombin time, D-dimer, tissue plasminogen activator (tPA), plasminogen activator inhibitor 1 (PAI-

287 accounting for tPA (tissue-type plasminogen activator) treatment.

288 he std20S or i20S subtype to any of its PA28 activator triggers allosteric changes that are specific

289 the expression of urokinase-type plasminogen activator (uPA) and/or matrix metalloproteinases (MMPs)

290 hemical and biophysical studies suggest that activators use nonspecific hydrophobic and/or electrosta

291 on a set of virally encoded transcriptional activators (vTAs) that hijack the host transcriptional m

292 Rather, the bacteria-derived prothrombin activator vWbp was identified as the source of the throm

293 ulator) can interact with the Arp2/3 complex activator WASF3, and efficiently recruits it to the prim

294 and enantioselectivity, with a fluorophilic activator, which assists the oxidative addition of the C

295 YAP/transcriptional co-activator with a PDZ-binding domain (TAZ) silencing resu

296 her cyclic guanosine monophosphate signaling activators worked synergistically with the glutathione p

297 The intermediate clade transcriptional activator WOX9 functions together with the modern clade

298 on of the proto-oncogenic transcriptional co-activator YAP.

299 also discovered that the transcriptional co-activators YAP and TAZ are required to maintain PROX1 ex

300 nes is coordinated by the transcriptional co-activator Yorkie with its major regulatory input provide