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1 structure, all of which seem to affect ECRs acutely.
2 ctively decreased ethanol intakes when given acutely (0.03-1.0 mg/kg, i.m.), whereas the MOP antagoni
4 we examined the consequences of locally and acutely ablating terminal Schwann cells (tSCs) at the ad
6 These results support the notion that ISO acutely accelerates oxidative metabolism of glucose to m
7 unique transcriptional signature present in acutely activated and clonally-expanded T cells that bec
8 elated peptide (AgRP)-expressing neurons are acutely activated by caloric need, and this acute activa
9 nterneurons express CRF-R1 receptors and are acutely activated by the neuropeptide CRF that is releas
12 capacity partly allows animals and plants to acutely adapt to oxygen deprivation, its functional and
14 h clinical findings and long-term outcome in acutely admitted patients with suspected acute coronary
15 ponin (cTn) elevation is a common finding in acutely admitted patients, even in the absence of acute
16 idities and predicts major adverse events in acutely admitted patients, in whom no definite diagnosis
17 eatment of ICI toxicities, which might occur acutely, affect any organ system, and produce many disti
20 on of infiltration of these cells into brain acutely after TBI would attenuate secondary damage and p
21 lungs of TBI + Sp mice were immunosuppressed acutely after traumatic brain injury and could not produ
22 d or early third trimester to an intense and acutely aggravating systemic disorder with an important
23 age 63.86 (11.31) years) were recruited post-acutely along with age- and sex-matched healthy controls
25 ll transcriptome mapping, we report that THC acutely alters gene expression in 15,973 blood cells.
26 A new study reveals that a high-sugar diet acutely alters human sperm small RNA profiles after 1 we
29 were best explained by the existence of both acutely and chronically infected individuals and by seas
32 vo disrupted astrocyte Ca2+ homeostasis both acutely and chronically, which led to the down-regulatio
34 doses up to 3.8 mug are female-specific both acutely and following central and peripheral priming.
37 ts developing corticostriatal circuits, both acutely and longer-term, during the first postnatal week
38 in the bloodstream: BK dysfunction recovered acutely and over time (the latter via an increase in LRR
40 use CA1 hippocampal pyramidal neurons, AK-42 acutely and reversibly inhibits CLC-2 currents; no effec
42 s to corticostriatal glutamatergic signaling acutely, and we hypothesize that VU0364572 may oppose th
43 havioral and electrophysiological effects of acutely applied synthetic Abeta oligomers in male and fe
47 stitutions, big and small, and all the while acutely aware of the impact of my Blackness on my scienc
48 global spread of SARS-CoV-2, we have become acutely aware of the inadequacies of our ability to resp
49 f the D2 antagonist haloperidol administered acutely before a cued associative recall task of previou
53 cytokine that has been shown to be produced acutely by skeletal muscle in response to exercise, yet
54 seed-competent misfolded tau species do not acutely cause cell death, but instead initiate discrete
55 uncoupling whether the assay temperature was acutely changed from 20 to 30 degrees C or 30 to 20 degr
57 an unanticipated presynaptic mechanism that acutely changes synaptic ultrastructure and regulates sy
58 e dorsoventral axis of the hippocampus could acutely, chronically, and differentially promote context
64 potential in a large cohort of patients with acutely decompensated cirrhosis (AD, n = 52) or acute-on
65 t (de novo heart failure (HF)) or worsening (acutely decompensated heart failure (ADHF)) of symptoms
69 Ex vivo studies revealed that PKC activation acutely decreased DAT surface expression selectively in
71 ne, the substrate for NO production, becomes acutely deficient in SCD patients with vaso-occlusive pa
73 damage response/DNA repair regime that when acutely depleted sensitize FANCJ CRISPR knockout cells t
76 C57BL/6 (Nod1-/-) and INS-GAS (Nod1-/-) mice acutely developed more severe gastritis, and INS-GAS (No
77 and direct protein kinase C (PKC) activation acutely diminishes DAT surface expression by acceleratin
80 Here, we generated a floxed B2m mouse to acutely down-regulate MHC-I in vivo in a host that norma
81 LASSO approach was used to select drugs that acutely either increase or decrease the apparent risk of
84 ses rubella and ruhugu viruses, was found in acutely encephalitic placental and marsupial animals at
86 le acids such as chenodeoxycholic acid (CDC) acutely enhance insulin secretion via the farnesoid X re
87 modulated amygdala reactivity with IFN-alpha acutely enhancing right amygdala responses to sad (compa
89 ng loose-patch nerve fiber recordings in the acutely excised mouse crista ampullaris of the semicircu
92 pheral blood mononuclear cells obtained from acutely (Fiebig I-III) and chronically infected individu
95 ngs suggested an important effector role for acutely generated cytotoxic CD4(+) T cells that could po
99 s included requests for scanning practice on acutely ill ICU patients and prior information on the ch
101 ween June 27, 2015, and April 21, 2017, 3634 acutely ill infants were enrolled, of whom 1943 were enr
103 iagnose these infections when the patient is acutely ill leads to excess morbidity and mortality.
106 in Post-Hospital Discharge Patients) studied acutely ill medical patients with additional risk factor
107 le depletion on post-transplant mortality in acutely ill men with cirrhosis undergoing urgent liver t
108 mic presents a global challenge for managing acutely ill patients and complications from viral infect
109 use of antibody testing in identification of acutely ill patients or in epidemiological settings.
110 monstrates a mixed fibrinolytic phenotype in acutely ill patients with cirrhosis with baseline hypofi
113 sed ICU admissions, are more chronically and acutely ill, and more frequently have sepsis than those
114 HIV+, age >= 14 years, on ART >6 months, not acutely ill, CD4 count not <200 cells/mm3) and willingne
117 rays for recording single-unit activity were acutely implanted into the orbitofrontal cortex, anterio
120 esults suggest that a single drink of KE may acutely improve metabolic control in individuals with ob
123 hile angiotensin II increased blood pressure acutely in all animals, VEGFCc156s-treated animals displ
124 ed virus to knockout endogenous hepatic Insr acutely in floxed Insr mice (liver insulin receptor knoc
125 t low-avidity IgG responses to BPI can arise acutely in response to bacteremia and that this associat
126 ur findings suggest that activating 5-HT(4)R acutely in the mPFC or targeting mPFC pyramidal cell ter
127 In addition to providing a new tool for acutely inactivating eIF4E in cells, our computational a
128 pothesis that VEGF-induced vascular leak can acutely increase atrial arrhythmia susceptibility by dis
129 gh PF rapidly activates AMPK, its ability to acutely increase glucose uptake and suppress glucose pro
130 lidated 64 activators and 65 inhibitors that acutely increase or rapidly decrease cell-surface Glut4
131 though opioids and most other drugs of abuse acutely increase signaling mediated by midbrain dopamine
132 rly when performed by unfit individuals, can acutely increase the risk of sudden cardiac death and ac
134 ones at the lower doses, but post-high dose, acutely increased renin activity (Normal: p < 0.001; HF:
137 ffinity NMDA receptor antagonist, memantine, acutely increases electrophysiological measures of audit
138 spring Daylight Saving Time (DST) transition acutely increases motor vehicle accident (MVA) risk ("DS
139 he single-cell level revealed that ER stress acutely increases the frequency of intracellular Ca(2+)
140 mised PI3K pathway regulation resultant from acutely induced B cell-targeted haploinsufficiency of PT
143 izure models in mouse hippocampal slices and acutely induced seizures in rats in vivo to determine me
146 connectivity, it is plausible that nicotine acutely induces this shift and alters NAcc functional co
149 and, to a much lower extent, also in dLNs of acutely infected C57BL/6 mice but became undetectable at
152 into the mechanism for treatment failure in acutely infected macaques would be important for the the
153 itory effect was robust but transient in the acutely infected macaques, despite the fact that all mac
154 of S. pneumoniae foci observed in hearts of acutely infected mice and serum levels of troponin I.
155 in vivo revealed that pulmonary necrosis in acutely infected mice is associated with reduced Gpx4 ex
156 irus (EBOV) proteome was characterized in an acutely infected patient receiving supportive care alone
157 particles bearing HCV envelope proteins from acutely infected patients, we show that HCV variants iso
159 nt complication in pregnant women who become acutely infected with Brucella melitensis is spontaneous
160 African women, and pregnant women who become acutely infected with HIV account for up to a third of v
161 IgA antibody ELISA testing, 61 (75.3%) were acutely infected with T. gondii, while of the 547 who we
163 IgA and IgM antibody tests, 61 (85.9%) were acutely infected, whereas 24 (19.2%) of the 125 women wh
164 contrast, it is present in plasma from mice acutely inflamed by injection of high dose of lipopolysa
168 +) and membrane electrical oscillations were acutely inhibited by YM58483, which blocks store-operate
169 l microscopy, we demonstrate that cells with acutely inhibited CDK4/6 enter the cell cycle with a slo
175 cultured intestinal epithelial cells and in acutely injured mucosa decreased the detrimental effects
179 al expansion of Kim1+ cells, indicating that acutely injured, dedifferentiated proximal tubule cells,
180 lamp recordings, we further demonstrate that acutely introducing an N-terminal fragment of FMRP into
181 , but only minor leukocyte infiltration into acutely ischemic-reperfused cortex and negligible vascul
182 tter can be safely delivered onto neurons in acutely isolated brain slices, thereby enabling high-res
184 ional and accessible chromatin landscapes of acutely isolated mouse CNS ECs versus mouse CNS ECs in s
186 Compared to wild type, Ca(2+) imaging in acutely isolated preparations of the retina and the cere
188 testinal mucosa, impaired cAMP generation in acutely isolated small intestinal epithelial cells, and
190 sation, we used short hairpin RNA (shRNA) to acutely knock down Sgce in the adult mouse and found tha
192 Disturbed sleep and increased wakefulness acutely lead to increased Abeta production and decreased
193 of gammadelta T cells improved survival from acutely lethal Mycobacterium infection or TSST-1 adminis
196 Together, these results show that histamine acutely modulates developing striatal neurons and synaps
197 ood mononuclear cells from naive and matched acutely (n = 4) or chronically (n = 12) SIV-infected rhe
198 e and reliable anti-influenza treatments are acutely needed and passive immunizations using broadly n
201 We found that administration of aripiprazole acutely or after 1 or 7 days of withdrawal from 21-day r
206 stments allow the exertion of high forces in acutely painful conditions but could eventually lead to
207 But how somatosensory neurons transduce acutely painful mechanical forces is largely unknown and
208 onstrate that DHA (500 nmol/kg) administered acutely post-injury confers neuroprotection and enhances
209 n together, these data suggest that VEGF can acutely predispose otherwise normal hearts to atrial arr
210 hoton imaging of dendritic spine motility in acutely prepared brain slices from female and male mice
212 Sepsis-associated encephalopathy (SAE) is an acutely progressing brain dysfunction induced by systemi
213 pothalamus fire phasic bursts of activity to acutely promote swimming and modulate audiomotor behavio
214 sts that interstitial edema in the heart can acutely promote ventricular arrhythmias by disrupting ve
215 RG239 and tauroursodeoxycholic acid (TUDCA), acutely promoted stimulus-secretion coupling (SSC).
216 (Rap-GEF4) controls fusion pore behavior by acutely recruiting two pore-restricting proteins, amisyn
219 f hyperacetylated proteins in the context of acutely reduced Acetyl-CoA levels under nutrient starvat
220 and mitigated by glucose, demonstrating that acutely reduced glucose metabolism impairs cognition sel
222 ross-over design to test the hypothesis that acutely-reduced CBF (using a pharmacological aid; indome
223 s-over design, we tested the hypothesis that acutely-reduced CBF (using indomethacin [1.2 mg kg(-1) o
230 rast to oncogenic kinases, whose function is acutely regulated by transient phosphorylation, PKC is c
231 t studies have highlighted the importance of acutely regulated cyclic nucleotides and their effectors
232 results revealed that this pool of ceramide acutely regulates cell adhesion and cell migration pathw
234 sory signals are synaptically transmitted to acutely relieve nCa(V) inactivation, enabling mechanosen
235 s, in the absence of muscle contraction, can acutely render the vascular endothelium more insulin-res
236 Here we show, in a mouse model, that IL-2 is acutely required to maintain T(reg) cells and immunologi
237 try revealed that while SCN(VIP) neurons are acutely responsive to light, their activity is otherwise
241 r ZnT8 levels, but proinflammatory cytokines acutely, reversibly, and gradually down-regulated ZnT8.
242 e dyssynchrony caused by DDD pacing could be acutely reverted by right atrial pacing (AAI) only.
243 in paired serum and nasal wash samples from acutely RSV-A-infected HCT recipients who recovered earl
244 Ceramide and the two isoforms of ASM were acutely secreted in the blood serum of wild-type mice af
249 acokinetics of the infused LSEVh-LS-F in the acutely SHIV-infected macaques significantly differed fr
251 changes in the mechanical properties of the acutely (softer) or chronically (stiffer) demyelinated b
253 and PKA-dependent phosphorylation of Ser(16) acutely stimulate the sarcoplasmic reticulum calcium pum
254 LH) via activation of protein kinase A (PKA) acutely stimulates luteal progesterone synthesis via a c
256 ss, we performed transcriptional analysis in acutely stressed mouse neurons, followed by functional c
258 ractions under normal growth and chronic and acutely stressful conditions, quantitative proteomics st
259 posures to poverty, chronic adversities, and acutely stressful events have been linked to maladaptive
261 on time: 10 min; IQR: 6 to 13 min) were 100% acutely successful with the multispline PFA catheter alo
264 clusion criteria included if the patient was acutely suicidal or had a psychiatric condition that aff
265 violet photostimulation during cold exposure acutely suppresses BAT temperature in wild-type mice but
267 natally infected with Zika virus (ZIKV) were acutely susceptible to high viremia and neurological dam
269 and requisite biophysical characteristics of acutely synaptotoxic ex vivo PrPSc derived from the brai
271 ompletely defined, we recently reported that acutely synaptotoxic PrPSc appeared to be oligomeric.
274 Using this biosensor, we found that 2-5A was acutely synthesized by cells in response to dsRNA sensin
276 the targeted elucidation of complex, local, acutely temporally dynamic interstitia through its appli
277 an both establish memory during training and acutely terminate learned search behavior in a subsequen
285 sation of antiretroviral therapy (ART) in 18 acutely treated and durably suppressed individuals.
287 , closely-monitored ATI in participants with acutely treated HIV, except a MRS alteration in basal ga
290 older had an episode of psychotic depression acutely treated with sertraline plus olanzapine for up t
293 We performed transcriptomic analysis on acutely UV-exposed human skin and integrated those findi
294 transcriptional signatures in common between acutely UV-exposed skin, wounded skin, and cuSCC tumors,
295 regulator purR resulted in a strain that was acutely virulent in bloodstream infection models in mice
297 ive multiple courses of antibiotics, and are acutely vulnerable to the threat of multidrug-resistant
298 The brain of an enrolled subject imaged acutely was procured following death for evaluation of t