ライフサイエンスコーパス: acyl-coenzyme A

1 lglycerol using 2-monoacylglycerol and fatty acyl coenzyme A.

2 esters from cholesterol and long-chain fatty acyl coenzyme A.

3 an endogenous 12-LOX inhibitor, a long-chain acyl coenzyme A.

4 nthesis from lysophosphatidic acid (LPA) and acyl-coenzyme A.

5 ition of lactate dehydrogenase by long-chain acyl-coenzyme A.

6 at accommodates nevanimibe and an endogenous acyl-coenzyme A.

7 The enzyme acyl coenzyme A:1-acyllysophosphatidylcholine acyltransf

8 FadR is a dimeric acyl coenzyme A (acyl CoA)-binding protein and transcrip

9 eins copurify with the Golgi adaptor protein acyl coenzyme A (acyl-CoA) binding domain protein 3 (ACB

10 iveness of various perdeuterated short-chain acyl coenzyme A (acyl-CoA) compounds as starter units fo

11 of an architecturally distinct subfamily of acyl coenzyme A (acyl-CoA) dehydrogenase (ACAD) enzymes

12 type I polyketide synthases (pltB, pltC), an acyl coenzyme A (acyl-CoA) dehydrogenase (pltE), an acyl

13 acylation process is the recognition of free acyl coenzyme A (acyl-CoA) from the lipid bilayer.

14 encodes a predicted protein with homology to acyl coenzyme A (acyl-CoA) ligases.

15 ion of carnitine fatty acid transferase with acyl coenzyme A (acyl-CoA) occurred.

16 A5174 confirmed a preference for short-chain acyl coenzyme A (acyl-CoA) substrates, supporting the id

17 Long-chain acyl coenzyme A (acyl-CoA) synthetase isoform 1 (ACSL1)

18 The AMP-forming acyl coenzyme A (acyl-CoA) synthetases are a large class

19 Short- and medium-chain acyl coenzyme A (acyl-CoA) synthetases catalyze the form

20 arbons or longer rescue growth by generating acyl coenzyme A (acyl-CoA) thioester beta-oxidation degr

21 n and activity of the long-chain cytoplasmic acyl coenzyme A (acyl-CoA) thioesterase 7 (ACOT7) to reg

22 t protein demonstrated both KAS activity and acyl coenzyme A (acyl-CoA):ACP transacylase (ACAT) activ

23 In vitro experiments point to fatty acyl coenzymes A (acyl-CoAs) rather than unesterified fa

24 Children with medium-chain acyl-coenzyme A (acyl-CoA) dehydrogenase defects can met

25 O is the transport of cytoplasmic long chain acyl-coenzyme A (acyl-CoA) into the mitochondrial matrix

26 nnected by a single system intermediate, the acyl-coenzyme A (acyl-CoA) pool.

27 Recent measurements of cellular acyl-coenzyme A (acyl-CoA) pools highlight the potential

28 Acyl-coenzyme A (acyl-CoA) species are cofactors for num

29 The 11 long-chain (ACSL) and very long chain acyl-coenzyme A (acyl-CoA) synthetases [(ACSVL)/fatty ac

30 protein" in sequence databases, exhibits an acyl-coenzyme A (acyl-CoA) thioesterase "hot dog" fold w

31 out fractionation and processing to quantify acyl-coenzyme A (acyl-CoA) thioesters in subcellular com

32 control of the activity of short-chain fatty acyl-coenzyme A (adenosine monophosphate-forming) synthe

33 Transmembrane domains of the acyl-coenzyme A and acyl phosphatidylcholine-utilizing d

34 I ceramide synthase that uses C16 fatty acid acyl-coenzyme A and dihydroxy LCB substrates but increas

35 posttranslational modifications derived from acyl-coenzyme A and has been demonstrated to regulate nu

36 Upon incubation of the enzyme with acyl-coenzyme A and reduced nicotinamide adenine dinucle

37 ide synthases that use very-long-chain fatty acyl-coenzyme A and trihydroxy LCB substrates.

38 ys using either acyl-acyl carrier protein or acyl coenzyme A as the substrate.

39 contrast, the purified acyltransferase uses acyl-coenzyme A as an acyl donor and shows no such prefe

40 while similar in vitro analyses using fatty acyl-coenzyme A as the substrate yielded medium-chain al

41 s interacting partner, Golgi adaptor protein acyl-coenzyme A binding domain containing protein 3 (ACB

42 , we uncover that the Golgi resident protein acyl-coenzyme A binding domain-containing 3 (ACBD3) serv

43 ombined experimental and simulation study of acyl-coenzyme A binding protein (ACBP), a two-state fold

44 ing temperature as the different variants of acyl-coenzyme A binding protein have similar m-values wh

45 The tissue hormone acyl coenzyme A-binding protein (ACBP, encoded by the ge

46 Here, we identify the PO membrane protein acyl-coenzyme A-binding domain protein 5 (ACBD5) as a bi

47 n of the peroxisomal membrane protein ACBD5 (acyl-coenzyme A-binding domain protein 5) and the ER-res

48 nd the peroxisomal proteins ACBD4 and ACBD5 (acyl-coenzyme A-binding domain protein).

49 Low-molecular mass (10 kD) cytosolic acyl-coenzyme A-binding protein (ACBP) has a substantial

50 Here we show that acyl-coenzyme A-binding protein (ACBP) potently facilita

51 SAR-related proteins THIOREDOXIN h3, ACYL-COENZYME A-BINDING PROTEIN6, and PATHOGENESIS-RELAT

52 ough the post-translational biotinylation of acyl coenzyme A carboxylases.

53 giotensin-converting enzyme inhibitor, or an acyl coenzyme A-cholesterol acyltransferase inhibitor.

54 dysfunction of the sterol esterifying enzyme acyl-coenzyme A-cholesterol acyltransferase (ACAT), whic

55 We show that 25HC-mediated activation of acyl coenzyme A: cholesterol acyltransferase (ACAT) in t

56 Previous studies have identified acyl-coenzyme A: cholesterol acyltransferase (ACAT), an

57 tion in 1993 of the first molecular probe of acyl-coenzyme A: cholesterol acyltransferase provided a

58 to an esterified storage form by the enzyme acyl-coenzyme A: cholesterol acyltransferase, is a criti

59 Acyl coenzyme A:cholesterol acyltransferase (ACAT) (EC 2

60 The inhibition of macrophage acyl coenzyme A:cholesterol acyltransferase (ACAT), whic

61 ubstrates for cholesteryl ester synthesis by acyl coenzyme A:cholesterol acyltransferase (ACAT).

62 The enzyme acyl coenzyme A:cholesterol acyltransferase 1 (ACAT1) me

63 for cholesterol ester formation in tissues, acyl coenzyme A:cholesterol acyltransferase types 1 and

64 roteins, monocyte chemoattractant protein-1, acyl coenzyme A:cholesterol acyltransferase, and tissue

65 y lipoprotein cholesterol with or without an acyl-coenzyme A:cholesterol acyl-transferase inhibitor m

66 , fatty acyl Coenzyme A hydrolysis (FACoAH), acyl-Coenzyme A:cholesterol acyltransfer (ACAT), and fat

67 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) activ

68 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) catal

69 The enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT) ester

70 nd in various pathophysiological conditions, acyl-coenzyme A:cholesterol acyltransferase (ACAT) has a

71 The rationale was that the acyl-coenzyme A:cholesterol acyltransferase (ACAT) in ho

72 We have found previously that acyl-coenzyme A:cholesterol acyltransferase (ACAT) inhib

73 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) is a

74 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) is an

75 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) is an

76 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) is an

77 Acyl-coenzyme A:cholesterol acyltransferase (ACAT) plays

78 Cholesterol trafficking to acyl-coenzyme A:cholesterol acyltransferase (ACAT) was a

79 substrate and/or as activator for the enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT), by m

80 the physical interaction of the major SOAT, acyl-coenzyme A:cholesterol acyltransferase (ACAT)-relat

81 nes with similarity to a human cDNA encoding acyl-coenzyme A:cholesterol acyltransferase (ACAT).

82 o express the cholesterol-esterifying enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT1), but

83 Macrophage acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) an

84 Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) is

85 Acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1), a

86 Human acyl-coenzyme A:cholesterol acyltransferase 1 (hACAT1) e

87 y-3-methyl-glutaryl-coenzyme A reductase and acyl-coenzyme A:cholesterol acyltransferase 2 in infecte

88 liver is known to be catalyzed by the enzyme acyl-coenzyme A:cholesterol acyltransferase, ACAT, the n

89 nzyme sterol O-acyltransferase 1 (also named acyl-coenzyme A:cholesterol acyltransferase, ACAT1) tran

90 In addition to acyl-coenzyme A:cholesterol acyltransferase-1 (ACAT1), a

91 und O-acyltransferase (MBOAT) enzyme family, acyl-coenzyme A:cholesterol acyltransferases (ACATs) cat

92 tracellular esterification of cholesterol by acyl-coenzyme A:cholesterol O-acyltransferase (ACAT).

93 Compound 1a increased esterification by acyl-coenzyme A:cholesteryl acyltransferase in NPC1 muta

94 ylates: the former as intermediates in fatty acyl coenzyme A (CoA) formation and the latter as precur

95 ing from the disruption of the gene encoding acyl coenzyme A (CoA) oxidase (AOX).

96 y sequential decarboxylative condensation of acyl coenzyme A (CoA) precursors, and the C-C bond-formi

97 es a decarboxylative condensation between an acyl coenzyme A (CoA) primer and malonyl-ACP.

98 tial carbon-carbon bond forming step between acyl coenzyme A (CoA) substrates offer a versatile route

99 a mitochondrion-associated long-chain fatty acyl coenzyme A (CoA) thioesterase that is highly expres

100 Acyl coenzyme A (CoA)-binding protein (ACBP; AcbA in Dic

101 diates in the unconventional secretion of an acyl coenzyme A (CoA)-binding protein that lacks an endo

102 ze an N-acyltransferase reaction using fatty acyl-coenzyme A (CoA) and long-chain base (LCB) substrat

103 coupled with positive selection to identify acyl-coenzyme A (CoA) binding protein (ACBP) as a bone m

104 at cleaves the thioester bonds of inhibitory acyl-coenzyme A (CoA) by-products generated during beta-

105 The Mycobacterium tuberculosis acyl-coenzyme A (CoA) carboxylases provide the building

106 Two genes, Psyr_2474, encoding an acyl-coenzyme A (CoA) dehydrogenase, and Psyr_4843, enco

107 The Arabidopsis (Arabidopsis thaliana) acyl-coenzyme A (CoA) desaturase-like (ADS) gene family

108 urases showed some similarity to presumptive acyl-coenzyme A (CoA) desaturases found in animals and p

109 DNAs was identified that encode a homolog of acyl-coenzyme A (CoA) desaturases found in animals, fung

110 onarily conserved ER protein FIT2 as a fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatt

111 Fatty acyl-coenzyme A (CoA) esters play a central role in the

112 They are similar in sequence to fatty acyl-coenzyme A (CoA) ligases (FACLs).

113 FAR) enzymes catalyze the reduction of fatty acyl-coenzyme A (CoA) or fatty acyl-acyl carrier protein

114 maturity were correlated with changes in the acyl-coenzyme A (CoA) pool in developing seeds of transg

115 e condensation of malonyl-ACP with different acyl-coenzyme A (CoA) primers.

116 oding either an acyl-acyl carrier protein or acyl-coenzyme A (CoA) reductase.

117 duced levels of intermediate and anaplerotic acyl-coenzyme A (CoA) species incorporated into the Kreb

118 yze the condensation of two long-chain fatty acyl-coenzyme A (CoA) substrates.

119 as 36 fadD genes annotated as putative fatty acyl-coenzyme A (CoA) synthetase genes, which encode enz

120 h the acyl-acyl carrier protein thioesterase:acyl-coenzyme A (CoA) synthetase mediated export mechani

121 Acyl-coenzyme A (CoA) synthetases (ACSs, EC 6.2.1.3) cat

122 Long-chain acyl-coenzyme A (CoA) synthetases (LACSs) activate free

123 ) through its binding to specific long-chain acyl-coenzyme A (CoA) synthetases of the ACSL family.

124 oesterase superfamily member 2 (Them2) is an acyl-coenzyme A (CoA) thioesterase that catalyzes the hy

125 g can be specifically reversed by long-chain acyl-coenzyme A (CoA) thioesters.

126 The nonenzymatic reaction of acyl-coenzyme A (CoA) with Cys-GlcN-Ins to produce acyl-

127 ting lysophosphatidylethanolamine (LPE) with acyl-coenzyme A (CoA), designated LYSOPHOSPHATIDYLETHANO

128 hosphate generated during synthesis of fatty acyl-coenzyme A (CoA), the reaction catalyzed by an enzy

129 l for its enzymatic activity and a potential acyl-coenzyme A (CoA)-binding pocket, based on homology

130 Acyl-coenzyme A (CoA)-binding protein (ACBP), also known

131 of ligand binding on the energy landscape of acyl-coenzyme A (CoA)-binding protein (ACBP).

132 , we present the characterization of a novel acyl-coenzyme A (CoA)-dependent acyl-transferase that is

133 talyzing the final and committed step in the acyl-coenzyme A (CoA)-dependent biosynthesis of triacylg

134 the redox loop-driven reduction of CO(2) by acyl-coenzyme A (CoA).

135 s, sterol is esterified to a storage form by acyl-coenzyme A (CoA): cholesterol acyl transferase (ACA

136 Wax synthase (WS, fatty acyl-coenzyme A [coA]: fatty alcohol acyltransferase) ca

137 acuole fusion is stimulated by certain fatty acyl-coenzyme A compounds in a Sec18p-dependent fashion.

138 mitochondrial proteins shows that long-chain acyl coenzyme A dehydrogenase (LCAD) is hyperacetylated

139 tly decreased the expression of medium-chain acyl coenzyme A dehydrogenase (MCAD) and short-chain acy

140 a, mitochondrial complexes, and medium chain acyl coenzyme A dehydrogenase (MCAD) expression.

141 Expression of the gene encoding medium-chain acyl coenzyme A dehydrogenase (MCAD), a nuclearly encode

142 nzyme A dehydrogenase (MCAD) and short-chain acyl coenzyme A dehydrogenase (SCAD), involved in the re

143 The identity of the gene encoding acyl coenzyme A dehydrogenase is a major remaining myste

144 into chains of spores, SCO6938 is a probable acyl coenzyme A dehydrogenase that contributes to the pr

145 urs in the hearts of mice lacking long-chain acyl coenzyme A dehydrogenase.

146 CA oxidation, TAC did not change short-chain acyl coenzyme-A dehydrogenase content.

147 of a key beta-oxidation enzyme, medium chain acyl-coenzyme A dehydrogenase (MCAD), requires cis-actin

148 micromol x min(-1) x g(-1)) and medium chain acyl-coenzyme A dehydrogenase (MCAD; 1.8+/-0.1 versus 2.

149 Medium-chain acyl-coenzyme A dehydrogenase (MCAD; mouse gene Acadm; h

150 roduct have been investigated in short-chain acyl-coenzyme A dehydrogenase (SCAD) from Megasphaera el

151 We generated very-long-chain acyl-coenzyme A dehydrogenase (VLCAD)-deficient mice by

152 romosome 10q26.13 in the vicinity of ACADSB (acyl-Coenzyme A dehydrogenase), involved in cholesterol

153 erating factor (DAF, also known as CD55) and acyl-coenzyme A dehydrogenase, long chain, which are loc

154 iagnosed metabolic disorder was medium-chain acyl-coenzyme-A dehydrogenase deficiency.

155 amino acid sequence of IBAH and those of the acyl coenzyme A dehydrogenases.

156 jacent genes: single insertions in each of 2 acyl-coenzyme A dehydrogenases (fadE) plus 2 unique inse

157 ycle mediated by phospholipase A2 (PLA2) and acyl-coenzyme A-dependent monolysocardiolipin acyltransf

158 Binding of both aminoglycosides and acyl-coenzyme A derivatives is strongly enthalpically dr

159 parameters of binding of aminoglycosides and acyl-coenzyme A derivatives to AAC(6')-Iy and of two mut

160 ) while the association constants of several acyl-coenzyme A derivatives were similar (3.2 x 10(4)-4.

161 The recent cloning of a gene encoding acyl coenzyme A : diacylglycerol acyltransferase, an enz

162 gene encodes a protein similar to mammalian acyl coenzyme A: diacylglycerol acyltransferase (DGAT),

163 Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1)

164 Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1)

165 Acyl coenzyme A:diacylglycerol acyltransferase 1 (DGAT1)

166 Acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) is

167 In this study, we investigated the role of acyl-coenzyme A:diacylglycerol acyltransferase 2 (DGAT2)

168 onfirmed that hepatic specific inhibition of acyl-coenzyme A:diacylglycerol acyltransferase with anti

169 liver disease demonstrate that inhibition of acyl-coenzyme A:diacylglycerol acyltransferase, the enzy

170 ects of increased or decreased expression of ACYL-COENZYME A:DIACYLGLYCEROL ACYLTRANSFERASE1 (DGAT1)

171 TAG accumulation in sdp1 roots requires both ACYL-COENZYME A:DIACYLGLYCEROL ACYLTRANSFERASE1 (DGAT1)

172 12 alone (line CL37) or together with castor acyl:coenzyme A:diacylglycerol acyltransferase2 reduced

173 ure-guided mutational analyses suggests that acyl-coenzyme A enters the active site through the cytos

174 n and purification, with high recoveries, of acyl-coenzyme A esters differing widely in chain length

175 e quantitative isolation and purification of acyl-coenzyme A esters is presented.

176 Thus, acyl-coenzyme A esters were purified from both bovine re

177 at B. napus embryos have an endogenous fatty acyl-coenzyme A: fatty alcohol acyl-transferase activity

178 s: cholesterol ester hydrolysis (CEH), fatty acyl Coenzyme A hydrolysis (FACoAH), acyl-Coenzyme A:cho

179 d to decreased abundance of long-chain fatty acyl-coenzyme A in the mediobasal hypothalamus and blunt

180 ontrol appears to be the rate at which fatty acyl-coenzyme A is transported into the mitochondria by

181 Long-chain acyl-coenzyme A (LC-CoA) is a crucial metabolic intermed

182 tory effect of the FA metabolite, long-chain acyl-coenzyme A (LC-CoA).

183 We show that long-chain acyl-coenzyme A (LCACA) activates two related mitochondr

184 -associated domain and coenriches with fatty acyl-coenzyme A ligase Faa1 at LD bud sites.

185 Here, we identified acyl-coenzyme A:lysocardiolipin acyltransferase-1 (ALCAT

186 mes, carnitine acyltransferases, involved in acyl-coenzyme A metabolism and as a carrier for long-cha

187 Acyl coenzyme A:monoacylglycerol acyltransferase (MGAT)

188 es the transfer of an acyl chain from either acyl-coenzyme A or acyl-acyl carrier protein onto LPA to

189 by (a) direct binding of fatty acids, fatty acyl-coenzyme A, or oxidized fatty acids; (b) oxidized f

190 and induction of fatty acid metabolism genes acyl coenzyme A oxidase and carnitine palmitoyltransfera

191 of the POX1 gene, which encodes peroxisomal acyl coenzyme A oxidase in the yeast Saccharomyces cerev

192 in plant peroxisomes requires the action of acyl-coenzyme A oxidase (ACX).

193 related protein (Adrp), whereas it augmented acyl-coenzyme A oxidase 1 (Acox-1), proliferator-activat

194 roxisomal lipid metabolic enzyme peroxisomal acyl-coenzyme A oxidase 1 (ACOX1) and antioxidative enzy

195 Fatty acyl-coenzyme A oxidase 1 (ACOX1) knockout (ACOX1(-/-))

196 ion of the peroxisomal beta-oxidation enzyme acyl-coenzyme A oxidase 1 (ACOX1), which catabolizes ver

197 The idea that induction of acyl-coenzyme A oxidase leads to increased production of

198 e beta-oxidation double mutant acx1acx2 (for acyl-Coenzyme A oxidase), levels of TAG actually increas

199 in patients with deficiencies of peroxisomal acyl-coenzyme A oxidase, bifunctional enzyme, and 3-oxoa

200 , the sequence of the last 12 amino acids of acyl-coenzyme A oxidase.

201 In a database search for homologs of acyl-coenzyme A oxidases (ACX) in Arabidopsis, we identi

202 l groups (16:0, 18:1, 18:2, and 18:3) in the acyl-coenzyme A pool provide most of the acyl chains for

203 , DesT senses the overall composition of the acyl-coenzyme A pool to coordinate the expression of the

204 on of unsaturated fatty acids from saturated acyl-coenzyme A precursors.

205 Substantial differences in acyl-coenzyme A profiles between the retina and brain we

206 tep in which DMSP is modified by addition of acyl coenzyme A, rather than the immediate release of DM

207 a line expressing castor FA hydroxylase and acyl-Coenzyme A:RcDGAT2 in its seeds.

208 We purified an alcohol-forming fatty acyl-coenzyme A reductase (FAR) from developing embryos

209 evels of the suberin biosynthetic gene fatty acyl-coenzyme A reductase 3.1 (FAR3.1) in GbCGF2/3-silen

210 (CER1) and CER3 catalyzes the conversion of acyl-Coenzyme A's to alkanes with strict substrate speci

211 Mitochondrial acyl-coenzyme A species are emerging as important source

212 The acyl-Coenzyme A substrate for this acyltransferase accum

213 -acyl carrier protein substrates rather than acyl coenzyme A substrates.

214 acid synthase (mas) and fadD28, an adjoining acyl coenzyme A synthase gene, involved in the productio

215 This gene encodes a putative 3-keto acyl coenzyme A synthase--an enzyme involved in the synt

216 s fadD33 (Rv1345), a gene that may encode an acyl-coenzyme A synthase and which previously was not kn

217 t with 2 mumol/L triacsin C (an inhibitor of acyl coenzyme A synthases) inhibited [3H]14,15-EET incor

218 To determine if FATP1 is a long chain acyl coenzyme A synthetase, FATP1-Myc/His fusion protein

219 Acyl coenzyme A synthetase-1 (ACSL1) facilitates long-ch

220 model both contain significant increases in acyl coenzyme-A synthetase medium-chain 3 enzyme gene ex

221 l of this study is to explore parasite fatty acyl-coenzyme A synthetase (ACS) as a novel drug target.

222 ty of cells to activate (via very-long-chain acyl-coenzyme A synthetase [VLCS]) and subsequently degr

223 sis, which may be due to its very long chain acyl-coenzyme A synthetase activity.

224 Acyl-coenzyme A synthetase long-chain family member 4 (A

225 Acyl-coenzyme A synthetase long-chain family member 4 (A

226 bserved in thiolase (kat2-1) and peroxisomal acyl-Coenzyme A synthetase mutants (lacs6-1,lacs7-1), in

227 rospectroscopy, the cutin mutants long-chain acyl-coenzyme A synthetase2 (lacs2), permeable cuticle1

228 opollenin polyketide biosynthetic metabolon (ACYL COENZYME A SYNTHETASE5, POLYKETIDE SYNTHASE A [PKSA

229 This activation is mediated by long-chain acyl-coenzyme A synthetases (LACSs), which are encoded b

230 hingolipids and transcriptionally activating acyl-coenzyme A synthetases and fatty acid elongases to

231 und in all living organisms and includes the acyl-coenzyme A synthetases, 4-coumarate:coenzyme A liga

232 elta knockout plants have a higher level, of acyl-coenzyme A than the wild type.

233 Saturated fatty acyl coenzyme A thioesters activate HNF-4 alpha, while c

234 It catalyzes acyl-coenzyme A thioesters to synthesize naringenin chal

235 Ts catalyze the sequential esterification of acyl-coenzyme A thioesters to the R4, R3, R3', and R2 po

236 Minimal activity was observed with aliphatic acyl-coenzyme A thioesters, which ruled out PaaI functio

237 catalyse the transfer of an acyl group from acyl-coenzyme A to cholesterol to generate cholesteryl e

238 , from the FAR2-catalyzed reduction of fatty acyl-coenzyme A to fatty alcohols, which are possible pr

239 elta hydrolyzes phosphatidylcholine and also acyl-coenzyme A to release fatty acids.

240 the reaction is an acyl group transfer from acyl-coenzyme A to the active-site cysteine of the enzym

241 a grass-expanded and -diverged clade of BAHD acyl-coenzyme A-utilizing transferases identified four m

242 other metabolic intermediates generated from acyl-coenzyme A, which is synthesized using lipoylated m