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1 uto-disable syringe with a Helms intradermal adapter).
2 ona discharge device in a novel setup via an adapter.
3 g" of gold nanorods decorated by the surface adapter.
4 r preferred orientations shift away from the adapter.
5 a molecular clamp and as a microtubule-cargo adapter.
6 oxic stress and autophagy involving the Doa1 adapter.
7 2), in which TRAF3 serves as the NIK-binding adapter.
8 viral protein is also required to act as an adapter.
9 of nanoparticles using programmable surface adapters.
10 ALs adapters compared to presbyopic PALs non-adapters.
11 rs compared to incipient presbyopic PALs non-adapters.
12 via ligation of double-stranded DNA (dsDNA) adapters.
13 ays is adapter ligation using pre-adenylated adapters.
14 , possibly, cdc20 homolog 1 (Cdh1) E3 ligase adapters.
15 randomized splint ligation with a cleavable adapter, a design which resolves previous challenges ass
18 ing the concentration and dosing schedule of adapter administration, we document two methods that can
19 proteins provide docking sites for distinct adapter and effector proteins important for regulating d
20 le of the Toll/interleukin 1 (IL-1) receptor adapter and major inflammatory mediator myeloid differen
22 ce, implying that arrestins, multifunctional adapter and signaling proteins, play a vital role in med
24 via a canonical pathway involving the MyD88 adapter and the interleukin-1 receptor-associated kinase
25 l intradermal devices, including intradermal adapters and disposable-syringe jet injectors, have also
27 le-stranded excised oligomers are ligated to adapters and re-immunoprecipitated with damage-specific
28 ul whole-body point-light displays (PLDs) as adapters and were then asked to perform an explicit cate
30 ts; explore the various reported designs for adapters; and consider future opportunities for this tec
32 ite mutant of Fgfr1, we established that FRS adapters are necessary for mediating most or all FGFR1 s
34 of synaptic cargo via the lysosomal kinesin adapter Arl8 regulates AZ abundance to modulate global s
35 vation, NLRP3 forms an inflammasome with the adapter ASC, resulting in caspase-1 activation, release
36 d is capable of adenylating large amounts of adapter at ~100% efficiency and can efficiently adenylat
37 h a model in which Ltn1 uses 60S subunits as adapters, at least in part via its NTD, to target stalle
38 sidates the viral genome and functions as an adapter between the virus and the host cell machinery.
39 with APP tail-1 (PAT1) as a potential direct adapter between zipcode-binding protein 1 (ZBP1, a beta-
40 results in the sequestration of MyD88 (TLR2 adapter) by Act1/CIKS (IL17R adapter), thereby turning o
43 ater (p < 0.03) in incipient presbyopic PALs adapters compared to incipient presbyopic PALs non-adapt
45 DLBCL), engages the CARD11-MALT1-BCL10 (CBM) adapter complex to activate IkappaB kinase (IKK) and the
49 y, we conclude that proper use of bispecific adapters could potentially avoid a life-threatening CRS
56 ed with single guide RNAs (sgRNAs) targeting adapter dimer ligation products, alongside highly expres
57 g studies, highly abundant molecules such as adapter dimer products and tissue-specific microRNAs (mi
59 The structure suggests that the DUF is an adapter domain that stabilizes the aldehyde substrate bi
60 engagement of FRS and non-FRS intracellular adapters downstream of FGFRs could therefore in principl
61 arises during the ligation of single-strand adapters during library preparation, and that this ligat
62 cocktail of low-molecular-weight bispecific adapters, each comprised of fluorescein linked to a diff
63 Rsp5 ubiquitin ligase and its transmembrane adapters, Ear1 and Ssh4, which localize to endosome and
65 lopment as an example, we show here that FRS adapters exhibit some selectivity in their requirement f
66 levels of the MuvB core subunit LIN52, a key adapter for assembly of both the DREAM and MMB complexes
67 family protein TULP3 functions as a general adapter for ciliary trafficking of structurally diverse
75 n as an example to study the role of the FRS adapters FRS2 and FRS3 in mediating the functions of FGF
76 domain of VE-cadherin mediates an essential adapter function by binding directly to the transmembran
77 In summary, this study identifies a novel adapter function for VE-cadherin mediated by transmembra
78 a role for tRNA distinct from its canonical adapter function in translation, as cleavage of tRNAs by
80 BL1, via phosphorylated Tyr177, recruits the adapter GRB2-associated binding protein 2 (GAB2) as part
85 ce of either PTPN21 FERM domain or the cargo adapter Hook3 that binds the same region of KIF1C tail.
86 cifically, we found that overexpressed cargo adapter HookA (Hook in A. nidulans) missing its cargo-bi
88 97 or siRNA-mediated depletion of p97 or its adapters impairs Ku80 removal after non-homologous end j
89 a carefully designed cocktail of bispecific adapters in combination with antifluorescein CAR T cells
91 in (MyD88), and Toll-IL-1R domain-containing adapter inducing IFN-beta (TRIF)-dependent cytokine gene
92 daptor molecule Toll/IL-1R domain-containing adapter inducing IFN-beta and downstream production of t
93 D88-independent Toll/IL-1R domain-containing adapter inducing IFN-beta-IFN regulatory factor 3 pathwa
94 growth factor beta 1, TIR-domain containing adapter inducing interferon-beta (TRIF), TRIF-related ad
95 immunity are linked by TIR domain-containing adapter-inducing beta interferon (TRIF) during establish
96 volving Toll-IL-1-receptor domain-containing adapter-inducing IFN-alpha (TRIF) and nuclear factor kap
97 al for both MyD88- and TIR-domain-containing adapter-inducing IFN-beta (TRIF)-mediated signaling path
98 protein Toll/IL-1 receptor domain-containing adapter-inducing IFN-beta and responded poorly to TLR ag
99 of TLR4 with MyD88 and TIR domain-containing adapter-inducing IFN-beta, thereby dampening the activat
100 Toll/IL-1 resistance (TIR) domain-containing adapter-inducing interferon beta) and activation of the
101 nduced endosomal TRIF (TIR domain-containing adapter-inducing interferon beta) signaling pathways.
102 like receptor 3 (-/-), TIR-domain-containing adapter-inducing interferon-beta (-/-), and wild-type mi
103 like receptor 3 (-/-), TIR-domain-containing adapter-inducing interferon-beta (-/-), and wild-type mi
104 tein kinase 3 (RIPK3), TIR-domain-containing adapter-inducing interferon-beta (TRIF) and Z-DNA-bindin
105 a Toll/IL-1 receptor (TIR) domain-containing adapter-inducing interferon-beta (TRIF) but less so for
106 tion factor 88 (MyD88)/TIR-domain-containing adapter-inducing interferon-beta (TRIF) double knockout
107 response 88 (MyD88) or TIR-domain-containing adapter-inducing interferon-beta (TRIF) signaling pathwa
108 well as Toll-dependent TIR-domain-containing adapter-inducing interferon-beta (TRIF), which function
109 Toll/Interleukin-1R (TIR) domain-containing adapter-inducing interferon-beta (TRIF)-, TRIF-related a
110 receptor 3 (TLR3)- and TIR domain-containing adapter-inducing interferon-beta (TRIF)-dependent type I
112 he pretreatment of WT, TIR domain-containing adapter-inducing interferon-beta knockout, and MyD88 ada
113 adaptor protein TRIF (TIR-domain-containing adapter-inducing interferon-beta) is essential for GN, b
114 terleukin-1 receptor (TIR) domain-containing adapter-inducing interferon-beta-dependent response that
115 lated adaptor molecule/TIR domain-containing adapter-inducing interferon-beta-dependent signaling pat
116 nocytes by enhancing a TIR domain-containing adapter-inducing interferon-dependent response and favor
121 ription complex that includes the ubiquitous adapter Ldb1 along with b-HLH and/or GATA family transcr
122 tured by oligo-dT primers and processed into adapter-ligated cDNA libraries that were sequenced using
124 ter phosphatase treatment; hence, subsequent adapter ligation and cDNA amplification steps are exclus
125 vailable to address important issues such as adapter ligation bias, PCR amplification artefacts or to
128 MAT-seq circumvents the issue of inefficient adapter ligation, a characteristic of conventional RNA s
129 ves fragmentation of genomic DNA followed by adapter ligation, bisulfite conversion and limited ampli
131 inducing interferon-beta knockout, and MyD88 adapter-like knockout macrophages with gedunin (10 micro
132 The selective effect of gedunin on MyD88-adapter-like/myeloid differentiation primary response 88
134 sly revealed that syntabulin acts as a motor adapter linking kinesin-1 motor and presynaptic cargos.
135 between the monocyte populations is that the adapter Mal (encoded by TIRAP) has appeared crucial for
136 ng data files by trimming reads and removing adapters, mapping reads to a reference, counting gene fe
137 sphorylation does not occur by the canonical adapter mechanism demonstrated for other substrates, as
138 t also in cell survival, implying that other adapters mediate at least in part the signaling from FGF
139 Here, we revealed its function in cargo-adapter-mediated dynein activation in the model organism
140 itro in the absence or presence of the cargo adapter melanophilin (Mlph), which links myoVa to Rab27a
141 t both the myosin motor domain and the cargo adapter Mlph, which has an actin-binding domain that act
142 ith the adapter protein Rap1-GTP-interacting adapter molecule (RIAM) followed by the recruitment of t
145 signaling, levels of ionized calcium-binding adapter molecule 1 and glial fibrillary acidic protein,
146 panmicroglial marker ionized calcium-binding adapter molecule 1 was decreased in all AD cases and the
147 ein) and microglial (ionized calcium-binding adapter molecule 1) markers was performed to investigate
148 not differ regarding ionized calcium-binding adapter molecule 1+ immunoreactivity for microglia, sugg
149 hocyte expression of ionized calcium-binding adapter molecule 1, toll-like receptor 2, and toll-like
150 staining showed more ionized calcium-binding adapter molecule 1-positive cells in the ischemic cortex
151 r results suggest that the NHERF1 acts as an adapter molecule and promotes IgE/Ag-induced mast cell a
152 NZB gene encoding the SLAM signaling pathway adapter molecule EWS-activated transcript 2 (EAT-2) is p
153 m in cancer, with a focus on complement, the adapter molecule Stimulator of Interferon Genes, natural
154 ely TLR independent, but is dependent on the adapter molecule STING, suggesting that the type I IFN s
155 s an oxidative stress-responsive cytoplasmic adapter molecule that is an upstream regulator of both I
156 ase (IKK) subunit NEMO/IKKgamma (NEMO) is an adapter molecule that is critical for canonical activati
157 obility group box 1, IFN-gamma, TRIF-related adapter molecule, IRF-3, HIF-1, nucleotide-binding oligo
160 DDB-kinesin-1 complexes, formed using a DNA adapter, moved slowly and persistently, and blocking p15
162 For all TLRs except TLR3, recruitment of the adapter, myeloid differentiation primary response gene 8
164 he subcellular distribution of the organizer/adapter NOX p47(phox) subunit is altered in PVN dendrite
166 e demonstrate that Grp170 binds to Sel1L, an adapter of the transmembrane Hrd1 E3 ubiquitin ligase po
167 ry response protein 88 (MyD88), a downstream adapter of TLRs including TLR7, abolished the RNA-induce
168 ansmembrane signaling polypeptide and direct adapter of TREM2, as the most robust key driver gene in
172 low-cost mobile fundus examination using an adapter on a smartphone; however, key aspects such as im
173 blocks cell-surface recruitment of the MyD88 adapter, one of the earliest events in TLR signaling.
174 al enzyme L, and the oligomeric multimodular adapter P of Mononegavirales We outline the structural a
175 ting this process by silencing the mitophagy adapter p62/sequestosome-1 (SQSTM1) might mitigate myoto
181 ole of adhesion- and degranulation-promoting adapter protein (ADAP) in promoting CD8 T cell responses
182 T cell kinase (ITK) with the T cell-specific adapter protein (TSAD) promotes LCK-mediated phosphoryla
184 pansion by MSC EVs is mediated via the MyD88 adapter protein and is partially blocked by treatment wi
185 ngage caspase-1, in most cases requiring the adapter protein apoptosis-associated speck-like protein
186 Many inflammasome receptors require the adapter protein ASC [apoptosis-associated speck-like pro
188 ion lies CrK-like (CRKL), a gene encoding an adapter protein belonging to the Crk family that is invo
194 been suggested that the kinase CheA and the adapter protein CheW are integral for receptor connectiv
196 tively, these results identify a microtubule adapter protein critical for trafficking of HIV-1 in the
197 nd genetic approaches revealed that the ShcA adapter protein critically influences proliferation and
201 eceptor bound protein 10 (Grb10) is a signal adapter protein encoded by an imprinted gene that has ro
204 vitro Macrophages deficient in Mincle or its adapter protein Fc receptor gamma chain (FcRgamma) produ
208 ates that Toll-like receptor (TLR) signaling adapter protein interactions with Toll/Interleukin-1 Rec
209 e myeloid differentiation protein 88 (MyD88) adapter protein is an important mediator of kidney allog
210 that tyrosine phosphorylation of the T cell adapter protein LAT at position Y132 is a critical kinet
213 ing, the type 1 IL1 receptor or the receptor adapter protein MyD88, were not protected from tumor-ind
215 ell receptor (TCR) results in binding of the adapter protein Nck (noncatalytic region of tyrosine kin
216 PP2A and increased its association with the adapter protein neuroblast differentiation-associated pr
218 roteins adhesion and degranulation promoting adapter protein or CT10 regulator of kinase/CT10 regulat
219 TRIP13 recognizes MAD2 with the help of the adapter protein p31(comet) We show that p31(comet) bindi
220 autophagosomal membranes and the autophagic adapter protein p62.IMPORTANCE Although the mechanisms b
222 -bound Ras-related protein 1 (Rap1) with the adapter protein Rap1-GTP-interacting adapter molecule (R
225 hese data identify an important role for the adapter protein ShcA in later stages of thymic T cell de
226 f PD-1 was associated with expression of the adapter protein SHP-2, which signals to NF-kappaB; howev
227 of CaV1.1 in tsA201 cells is promoted by the adapter protein Stac3, because recent work has shown tha
228 ts intracellular DNA and signals through the adapter protein STING to initiate the antiviral response
229 bitory regulation of the integrin-associated adapter protein talin coordinates cell-ECM adhesion duri
233 at RANKL controls the expression of 3BP2, an adapter protein that is required for activation of SRC t
234 tor (TNFR)-associated factor 6 (TRAF6) is an adapter protein that mediates a wide array of protein-pr
235 otein A repetitions predominant [GARP]), the adapter protein that tethers TGF-beta to the membrane.
236 l mitochondrial GTPases RHOT1 and RHOT2, the adapter protein TRAK2, the anterograde motor Kif5B, and
247 xample, multifunctional beta-arrestin (ARRB) adapter proteins are best known as regulators of G prote
249 s previously shown that extracellular 14-3-3 adapter proteins bind to APN and thereby induce the tran
252 This was attributed to the absence of both adapter proteins in platelets, as demonstrated by adopti
253 protein-tyrosine kinases, phosphatases, and adapter proteins interact to transmit signals from the T
254 TNF receptor-associated factor (TRAF)-family adapter proteins involved in TLR and TNFR pathways.
256 ractions between the tail and regions of the adapter proteins outside of the SH2/PTB domains are impo
258 mall Src homology domain 2 (SH2) and 3 (SH3) adapter proteins regulate cell fate and behavior by medi
260 ns (betaarrs) are versatile, multifunctional adapter proteins that are best known for their ability t
263 prime example is binding of the rigid 14-3-3 adapter proteins to their numerous partner proteins, who
266 w sequence evaluation, (2) read trimming and adapter removal, (3) read mapping and quality filtering,
268 function, whereas double deficiency of both adapters resulted in markedly increased signal transduct
269 lation of EC phenotype via an unconventional adapter role, assembling and anchoring a multifunctional
271 tion-based strategy that leaves behind 38-bp adapter sequences, which must be computationally removed
272 ull use of the sequence on both sides of the adapter site to build 'virtual libraries' of mate pairs,
273 o the centre of LAT-based complexes, and the adapter SLP-76 and actin molecules localize to the perip
274 naling loop whereby N-WASP and the endocytic adapter SNX18 promote lysophosphatidic acid-induced RhoA
275 e conversion and limited amplification using adapter-specific PCR primers in preparation for sequenci
277 M-PCR and unidirectionally ligated to bridge adapters; subsequent PCR steps amplify the single-strand
278 nsposase simultaneously cleaves DNA and adds adapters ('tagmentation') for paired-end DNA sequencing.
280 0) is a PSD-95, disc large, zona occludens-1 adapter that acts as a scaffold for signaling complexes
281 Here, we present a versatile DNA surface adapter that can programmably self-assemble into various
282 adjusting the dose of a low molecular weight adapter that must bridge between the CAR T cell and canc
284 gene, which encodes gigaxonin, an E3 ligase adapter that targets intermediate filament (IF) proteins
285 main containing proteins (BET) are chromatin adapters that bind acetylated histone marks via two tand
286 binding proteins (PCBPs) are multifunctional adapters that mediate interactions between nucleic acids
288 of MyD88 (TLR2 adapter) by Act1/CIKS (IL17R adapter), thereby turning off TLR2 signaling to restore
291 or was connected through a coaxial-waveguide adapter to the S parameter meter, by means of which the
292 Pipette tips were designed and 3D printed as adapters to fit most commercial 50-200 muL pipettes.
294 miseq does this by automating the process of adapter trimming, quality filtering, error correction, c
295 and the assembly vector is encoded by 'VEGAS adapter' (VA) sequences, which are orthogonal in sequenc
296 osin V motor Myo2 binds the vacuole-specific adapter Vac17 to attach to the vacuole/lysosome and init
297 In neurons whose response to the visual adapter was inhibited by simultaneous photo-stimulation,
298 ich SQSTM1/p62 plays a major role as a cargo adapter, we also were able to confirm that p62 binds to
299 photographers using the low-cost smartphone adapter were able to acquire optic nerve images at a sta