ライフサイエンスコーパス: adaptive

1 , FcRgamma(-) NK cells responded robustly to adaptive Ab-mediated signaling through CD16.

2 l); 2) the megaplasmids encode diverse niche-adaptive accessory traits, including multidrug resistanc

3 sub-habitat and respond in this way have an adaptive advantage over those who cannot.

4 Quorum sensing, in turn, may confer adaptive advantages on the mammalian immune system, espe

5 se and how their distinctive combinations of adaptive alleles are maintained despite hybridization wi

6 to investigate CD57(+) FcepsilonRIgamma(neg) adaptive and FcepsilonRIgamma(pos) conventional NK cell

7 ncreasingly recognized as modulators of both adaptive and innate immune responses, as well as players

8 Whether or not adaptive and pathological anxiety share mechanisms remai

9 daptation, making the relative importance of adaptive and stochastic processes in insular evolution d

10 shrinking baby lung is opposed by reactive, adaptive, and reparative processes.

11 telomere stress increases innate sensing and adaptive anti-tumor immunity and provide strong rational

12 e a versatile strategy for the generation of adaptive anti-tumour immune responses.

13 like program, which had crippling effects on adaptive antitumor immunity.

14 les tumors on the basis of the key player in adaptive antitumor response, CD8+ cells, and evaluates t

15 ms remains unknown, but if they do, induced (adaptive) anxiety could be used as an intermediate trans

16 nitored by an independent committee using an adaptive approach with interim analyses.

17 Here, we study transitions between adaptive associations of feather structure and carotenoi

18 We developed an automated adaptive atlas algorithm to segment the left ventricle o

19 ed in the PET images using the fuzzy locally adaptive Bayesian algorithm, and manually in the low-dos

20 the effort to determine the neural basis of adaptive behavior could benefit from renewed experimenta

21 Adaptive behavior is influenced by prepotent action-rewa

22 tical networks and gates plasticity enabling adaptive behavior.

23 task-dependent manner and guides subsequent adaptive behavior.

24 innate sensory cues are processed to elicit adaptive behavioral responses to threat and will help to

25 ->DH circuit can facilitate the selection of adaptive behaviors when current and past experiences are

26 These are common building blocks of general adaptive behaviors.

27 nitive and emotional processes in support of adaptive behaviors.

28 learned through active inference can support adaptive behaviour in spite of, and indeed because of, t

29 Adaptive behaviour is necessary to cope with the complex

30 ues and outcomes is a fundamental element of adaptive behaviour.

31 Factors associated with both adaptive benefits of CVp (wind pollination and seed disp

32 at differences in exposure, sensitivity, and adaptive capacity all contribute to heterogeneity in cli

33 ctors to reduce carbon emissions, strengthen adaptive capacity, and increase food security.

34 terium-specific, IFN-gamma-producing, purely adaptive CD8(+) alphabeta T, and CD4(+) alphabeta T(H)1(

35 oural therapies, other immunomodulators, and adaptive cell therapy, including chimeric antigen T-cell

36 may ultimately depend upon its capacity for adaptive change.

37 been previously reported to have potentially adaptive changes in single-species studies, and thus wou

38 bility to solve cognitive tasks depends upon adaptive changes in the organization of whole-brain func

39 xclusively in cell culture, thus lacking egg adaptive changes.

40 the same time also allow for resynthesis and adaptive chemical modification of the glycocalyx.

41 earning protocol for the rapid assessment of adaptive choice behavior in dynamic environments in rats

42 These adaptive choices elicited a suppression signal in the hi

43 Here we identify an adaptive circuit-based mechanism that enables Drosophila

44 s on the X Chromosome, we find evidence that adaptive cis-regulatory changes are more likely to drive

45 Adaptive coding of stimuli is well documented in percept

46 ndings reveal the existence of an underlying adaptive codon-based regulatory response inherent to the

47 This neglected aspect of adaptive cognition is discussed and illustrated from a c

48 as a general system for decision making via adaptive combination of stimulus-response learning and t

49 signaling trajectories, particularly in the adaptive compartments.

50 Instead, information is maintained in adaptive conductances that reduce firing rates and can b

51 ence individual specialization; however, its adaptive consequences are poorly understood, particularl

52 cribe respiratory pacing using a closed-loop adaptive controller that can self-adjust in real-time to

53 accessible through genetic change, enabling adaptive convergence independently of plasticity.

54 Thus, we find adaptive convergent genetic evolution to be a key driver

55 th intracellular innate immune responses and adaptive cytotoxic T cell responses.

56 potentially effective target for beta-based adaptive DBS.SIGNIFICANCE STATEMENT It is known that sub

57 Resilient mice exhibited an adaptive decrease in total running, appropriate food ant

58 and target groups that included less severe adaptive deficits in communication skills, similar funct

59 the primary outcome, with accounting for the adaptive design, yielded a risk difference of -19 percen

60 We found a significant signal of adaptive differentiation among plots separated by < 1 km

61 we apply modeling tools to better understand adaptive divergence of whitefish during the postglacial

62 We found that sea snakes underwent rapid adaptive diversification of their visual pigments when c

63 that within-host microevolution is rapid and adaptive during natural colonisation.

64 li (CS) can guide reward-seeking behavior in adaptive (e.g., locating food) and maladaptive (e.g., bi

65 These early adaptive effects in TAC were entirely mimicked in young

66 th others experiencing similar symptoms; and adaptive emotion regulation strategies amongst those wit

67 y of semiconductor devices by using the self-adaptive evaporative cooling of a lithium- and bromine-e

68 The role of phenotypic plasticity in adaptive evolution has been debated for decades.

69 well known that sexual reproduction enhances adaptive evolution in changing environments.

70 as a fundamental mechanism that drives rapid adaptive evolution in human populations.

71 ding of microbial catabolic diversity during adaptive evolution in response to xenobiotics released i

72 aptive trait, but the role of plasticity for adaptive evolution is still unclear [5-10].

73 gens and xenobiotics as important drivers of adaptive evolution of mammals.

74 tinal oxygenation played a vital role in the adaptive evolution of vision in teleost fishes.

75 that acts on gene expression and its role in adaptive evolution remain unknown(1,2).

76 Our approach uses two independent adaptive evolution steps to address the lack of experime

77 ew insights into the polyploidization-driven adaptive evolution would be useful for future breeding c

78 ed as a major driver of trait divergence and adaptive evolution, relatively little effort has focused

79 inant of the success of bacterial pathogens, adaptive evolution.

80 d cellular "choreography" and illustrates an adaptive feature that promotes bacteriome multiplication

81 Adaptive focusing can compensate for such aberration but

82 suggest that choice-confirmation bias may be adaptive for efficient learning of action-outcome contin

83 Is it adaptive for individuals to sense in which sub-habitat t

84 natural selection is capable of discovering adaptive forms of cell plasticity associated with comple

85 e examples where HGT has facilitated gain of adaptive functions and in some cases, underpinned major

86 pigenetics beyond the chromosome, instilling adaptive gene expression programs that are heritable ove

87 ecies can thereby increase the potential for adaptive gene flow between species so that adaptive intr

88 discover three causal SNPs of EPAS1, the key adaptive gene for Tibetans.

89 The analysis revealed their adaptive gene repertoire which was bared from 52% unique

90 This work lays the foundation for adaptive genetic circuits that can be tuned after their

91 , focusing on recent work that suggests such adaptive genome variation is linked to novel strategies

92 We documented adaptive habitat selection for seven species, non-ideal

93 state is sustained over time and defines an adaptive homeostasis in the infected macrophage.

94 ssential source of IL-12 for both innate and adaptive IFNgamma production, and inhibit follicular Th

95 lymphoid (Il2rg knockout mice [Il2rg (KO)]), adaptive immune (Rag1 knockout mice [Rag1 (KO)]), or bot

96 e function and regulation of both innate and adaptive immune cells in human WAT under conditions of o

97 40L-overexpressing CAR T cells on innate and adaptive immune cells, and provide a rationale for using

98 lly reprogramming the function of innate and adaptive immune cells.

99 cohorts, we identify peripheral and central adaptive immune changes in Alzheimer's disease.

100 an ocean of microbes without one arm of the adaptive immune defense suggests a high degree of immuno

101 gulate T-cell activation, may play a role in adaptive immune hyporesponsiveness.

102 responses that are often intensified by host adaptive immune pathways to profoundly advance disease s

103 licited both a stronger trained immunity and adaptive immune phenotype.

104 We discovered that the adaptive immune response against Staphylococcus aureus (

105 Vitamin A regulates the adaptive immune response and a modulatory impact on type

106 lations, and to verify the development of an adaptive immune response in infected individuals.METHODS

107 These results reveal an adaptive immune response in the blood and cerebrospinal

108 blishment of an anti-BP CD4 T cell-dependent adaptive immune response leading to anti-drug Abs produc

109 cell receptors (TCR) plays a key role in the adaptive immune response to infections.

110 ock syndrome, an escalation of the cytotoxic adaptive immune response triggered upon the binding of p

111 ith admixture-enabled selection for enhanced adaptive immune response.

112 subsequently initiating a well-orchestrated adaptive immune response.

113 uctural predetermination and dynamics of the adaptive immune response.

114 e and viral antigen burden with the regional adaptive immune response.

115 ring development of one arm of the mammalian adaptive immune response.

116 ation is a prerequisite for the induction of adaptive immune responses against pathogens and cancer.

117 tivity of the protease MALT1 is required for adaptive immune responses and regulatory T (Treg)-cell d

118 y high recurrence rates of UTIs, we examined adaptive immune responses in mouse bladders.

119 n, early pathogenesis, innate viral control, adaptive immune responses or the balance of inflammation

120 Innate and adaptive immune responses that prime myeloid cells, such

121 with a connection between aging and impaired adaptive immune responses to SARS-CoV-2.

122 ll surface proteins that regulate innate and adaptive immune responses to viral infection by engaging

123 lper cells in antiviral defense, influencing adaptive immune responses via interactions with dendriti

124 Few differences in adaptive immune responses were observed between the sexe

125 uated airway hyperresponsiveness, innate and adaptive immune responses, and type 2 cytokine productio

126 suppressed kidney damage without augmenting adaptive immune responses, suggesting it might offer a n

127 cal molecular links between innate cells and adaptive immune responses.

128 as potential adjuvants for the induction of adaptive immune responses.

129 cted cells and by mobilizing both innate and adaptive immune responses.

130 e development of inflammation and innate and adaptive immune responses.

131 subjected to the control of host innate and adaptive immune responses.

132 Lymphocyte migration is essential for adaptive immune surveillance.

133 ires reveal insights into the biology of the adaptive immune system and empower diagnostics and thera

134 Emergence of an adaptive immune system and more complex neural systems p

135 re the oldest jawed vertebrates that have an adaptive immune system based on the MHC and Ig superfami

136 ) that allows unprecedented profiling of the adaptive immune system in submucosal and mucosal isolate

137 solated from patients support a role for the adaptive immune system in the pathogenesis of IADRs.

138 The organizational integrity of the adaptive immune system is determined by functionally dis

139 The adaptive immune system responds to pathogens by selectin

140 the context of airway mucus obstruction, the adaptive immune system suppresses antibacterial macropha

141 B lymphocytes are important players of the adaptive immune system.

142 is an essential component of the innate and adaptive immune system.

143 CRISPR-Cas adaptive immune systems are used by prokaryotes to defen

144 understanding of the role of the innate and adaptive immune systems in the pathogenesis of heart fai

145 Bacteria have evolved sophisticated adaptive immune systems, called CRISPR-Cas, that provide

146 (Cas) genes, a diverse family of prokaryotic adaptive immune systems, have emerged as a biotechnologi

147 nvolve activation of cells of the innate and adaptive immune systems, with pivotal roles for pro-infl

148 all proteins secreted by cells in innate and adaptive immune systems.

149 tion time changes at 24-48 h and the ensuing adaptive immunity (R = 0.9831) at day 5 and the tumor in

150 ISPR system in bacteria and archaea provides adaptive immunity against mobile genetic elements.

151 nd widely in prokaryotes, where they provide adaptive immunity against virus infection and plasmid tr

152 CRISPR-Cas systems provide bacteria with adaptive immunity against viruses.

153 scriptional profile showed downregulation of adaptive immunity and induction of programs related to i

154 Cytotoxic T cells play a key role in adaptive immunity by killing infected or cancerous cells

155 IL-6) is a cytokine with critical innate and adaptive immunity functions.

156 host microbiome, their effect on innate and adaptive immunity in health and disease with a special f

157 her neural functions, induce both innate and adaptive immunity in NTNBC.

158 upports a critical role for inflammation and adaptive immunity in the onset of cancer and in shaping

159 ral crest formation are predicted to enhance adaptive immunity in TNBC while glia development, along

160 This cardinal feature of adaptive immunity is achieved by the assembly of a funct

161 Cas (CRISPR-associated) systems as a type of adaptive immunity to target and degrade foreign nucleic

162 Adaptive immunity vitally depends on major histocompatib

163 activation of gene networks associated with adaptive immunity was linked to the suppression of netwo

164 have existed long before the development of adaptive immunity, although they have been given differe

165 also promotes blood brain barrier integrity, adaptive immunity, and activation of microglia/macrophag

166 or CD8(+) T cells are important mediators of adaptive immunity, and receptor-ligand interactions that

167 ntrolled inflammatory response, dysregulated adaptive immunity, coagulation abnormalities, hemorrhage

168 CD8(+) T cells play a critical role in adaptive immunity, differentiating into CD8(+) memory T

169 ed in all mice with or without deficiency in adaptive immunity, indicating a critical role for innate

170 cells (DCs) play a critical role in shaping adaptive immunity.

171 , activate innate immune cells, and regulate adaptive immunity.

172 mation; and lack interference with innate or adaptive immunity.

173 s, leading to frequent anaemia and decreased adaptive immunity.

174 ells versus plasma cells is a major quest of adaptive immunity.

175 roviding an efficient short-cut to acquiring adaptive information, underpin the cumulative cultural e

176 r adaptive gene flow between species so that adaptive introgression is not simply happenstance.

177 that these regions could have resulted from adaptive introgression related to hibernation, indeed fi

178 sure, however, this can be addressed through adaptive laboratory evolution for increased ionizing rad

179 High performance is achieved with adaptive learning rate clipping of loss spikes and an au

180 mpus playing a multifaceted role in socially adaptive learning.

181 mpus playing a multifaceted role in socially adaptive learning.SIGNIFICANCE STATEMENT Adaptively navi

182 are one mechanism that seems to induce this adaptive life-history plasticity.

183 t data within a context of three widespread, adaptive life-history strategies-sexual dichromatism, ag

184 ssociation analyses identified 16 putatively adaptive loci related mainly to biotic and abiotic stres

185 e development of innate (NK) and innate-like adaptive lymphocytes (iNKT, MAIT, and Vdelta2(+) gammade

186 ighlighting the parallels between innate and adaptive lymphocytes, with a particular focus on NK cell

187 ulating specification programs of innate and adaptive lymphocytes.

188 ing region, is driving the development of an adaptive management system for the fishery.

189 vation applications, which are important for adaptive management.

190 The stress response is an adaptive means of maintaining physiological homeostasis

191 ocial-network plasticity and feedback as key adaptive mechanisms for refining individual and collecti

192 s to improve locomotor turning; however, the adaptive mechanisms involved are poorly understood.

193 A powerful feature of adaptive memory is its inherent flexibility.

194 meshes generated by the Geometry-preserving Adaptive MeshER software are suitable for use with numer

195 dramatic increase in knowledge that informs adaptive models of care, with an emphasis on articles pu

196 and implementation in devices are overcome, adaptive molecular crystals can have far-reaching implic

197 In these developments, the adaptive molecular crystals warrant particular attention

198 g from enzymes to synthetic catalysts, exert adaptive motifs to maximize their functionality.

199 Influenza antigens may undergo adaptive mutations during egg-based vaccine production.

200 ely and metagenome sequencing data revealing adaptive mutations during the experiment.

201 Mouse-adaptive mutations in the RV-A16 2C protein allowed for

202 Critically, our work suggests that adaptive myelination may be a mechanism that enables bra

203 pecialised face perception and highlight the adaptive nature of the face processing system.

204 tem aimed at reducing pain and looked for co-adaptive neural and behavioral changes.

205 However, the fate of the recently described adaptive NK cell population, endowed with increased abil

206 adrenergic signaling is required for optimal adaptive NK cell responses.

207 We combine adaptive optics ophthalmoscopy with calcium imaging to o

208 We show that adaptive optics scanning laser ophthalmoscopy can visual

209 iseased, with the unique capabilities of our adaptive optics-optical coherence tomography approach an

210 d that the E217G hairpin exhibits an altered adaptive packing behavior stemming from an additional GX

211 s, but do not conform to their own predicted adaptive peak.

212 .23), P < 0.0001] suggesting that this is an adaptive phenomenon.

213 e profile of human and murine MVPC toward an adaptive phenotype.

214 ared ancestry or independent evolution shape adaptive phenotypes.

215 dbacks may help to understand changes in the adaptive potential after disturbance of metacommunity hu

216 Our results, showing differential adaptive potential of bla(ampC) to combinations of aviba

217 onselected genetic variation and expands the adaptive potential of microbial populations.

218 ssisted gene flow interventions to boost the adaptive potential of specific coral populations.

219 dividual tree populations, and enhance their adaptive potential to rapidly changing environments.

220 he maintenance of high genetic diversity and adaptive potential under climate-change-related range ch

221 latter metric explains the most variation in adaptive potential, and significantly correlates with ac

222 ine learning automated approach: a Real-time Adaptive Predictive Indicator of Deterioration (RAPID) t

223 conditions, we conceive of it as an ongoing, adaptive process of assessing the environment, coping wi

224 We start by considering the adaptive process that has locked together the regulation

225 Fear and extinction learning are adaptive processes caused by molecular changes in specif

226 Without such a null model, the role of adaptive processes in shaping within- and between-popula

227 proving agricultural yield and understanding adaptive processes.

228 ecovery after acute kidney injury (AKI) with adaptive proliferation of tubular epithelial cells, but

229 ly inhibited growth but resulted in eventual adaptive proliferation.

230 This competition may serve an adaptive purpose, focusing encoding on experiences for w

231 ncurrent with previously proposed periods of adaptive radiation.

232 ential is the key to understanding explosive adaptive radiation.

233 ons has led them to play a major role in the adaptive radiations that occur when populations have acc

234 We did an open-label, pragmatic, adaptive, randomised controlled trial of adding oseltami

235 ed to 1 of 4 treatment combinations using an adaptive randomization protocol.

236 gering cell signaling pathways which lead to adaptive regulation of mRNA translation and protein synt

237 These genes display evidence of adaptive regulatory evolution within cities and dispropo

238 zed in resilient animals, in part through an adaptive reorganization of prefrontal cortical activity.

239 The greatest adaptive resilience to upper thermal stress was shown by

240 b-population benefits the swarm by enhancing adaptive resistance in the surviving cells.

241 immune infiltrate expressed higher levels of adaptive resistance pathways.

242 sights, we created trametiglue, which limits adaptive resistance to MEK inhibition by enhancing inter

243 sion of this theory, the internal predictive adaptive response (iPAR) model, by assessing whether acc

244 ogy of eagles, geographic differences in the adaptive response of caribou reproductive phenology to c

245 Coffee induces a health-promoting adaptive response of cells in the body.

246 demonstrate that Hfq foci have a role in the adaptive response of E. coli to long-term nitrogen starv

247 ment after clozapine exposure may reflect an adaptive response related to improved outcome rather tha

248 h menstrual dysfunction might have decreased adaptive response to exercise interventions.

249 ed nucleobases in DNA and RNA as part of the adaptive response to exogenous nucleic acid-alkylating a

250 out the role of histone PTMs in the cellular adaptive response to stress.

251 Although anxiety can be an adaptive response to unpredictable threats, pathological

252 primary infection despite that a protective adaptive response to UPEC infection was evident in the b

253 development of "short-but-heavy" roots as an adaptive response to water deficit in rice.

254 f HSCs to stress, and dysregulation of these adaptive-response mechanisms underlies the development o

255 uently inform the polarization of downstream adaptive responses depending upon identity and localizat

256 triggered photoreceptor ablation have shown adaptive responses in bipolar cells expected to support

257 sms that sense environmental changes trigger adaptive responses that ensure animals develop properly.

258 es of gene families, signaling networks, and adaptive responses that highlight the evolutionary traje

259 nisms responsible for this reduction include adaptive responses that increase acid excretion but lead

260 ranscriptional component, MED16, in the root adaptive responses to a scarce plant macronutrient, whic

261 Adaptive responses to ecological uncertainty may affect

262 ole of HIF2alpha, and link acute and chronic adaptive responses to hypoxia.

263 s may be a useful comparative model to study adaptive responses to SCI.

264 nnate immune response and activate antitumor adaptive responses, our finding indicates that targeted

265 assess the induction of trained immunity and adaptive responses, respectively.

266 in computing teaching signals that influence adaptive reward seeking.

267 curacy of estimated control group mortality, adaptive sample size strategy, plausibility of predicted

268 educe parameter correlations by implementing adaptive sampling and stimulation protocols compatible w

269 Several adaptive scenarios may have favored this functional dive

270 Adaptive schemes using previous viral load measurements

271 Our model suggests that adaptive shifts in consumer distribution patterns would

272 folded protein response (UPR) is a conserved adaptive signaling pathway that governs protein folding,

273 Herein, we describe an adaptive signaling plasticity of CRLF2-rearranged Ph-lik

274 ean populations, we found a clear and robust adaptive signature in the UK population by using a haplo

275 In mainland Europeans, the adaptive signature was detected in haplotype-based analy

276 ed cognitive-affective processes critical to adaptive social functioning.

277 against environmental fluctuations within an adaptive state should preclude exploration of new adapti

278 ive state should preclude exploration of new adaptive states when the environment changes.

279 ne fluidity modulation by desaturases in the adaptive strategies of Synechococcus cyanobacteria durin

280 We then discuss sophisticated adaptive strategies that bacteria have developed to enha

281 All vaccines boosted titers to HA with egg-adaptive substitutions, suggesting boosting from past an

282 support a crucial role of chitoporin in the adaptive survival of bacteria on chitinous nutrients.

283 arliest stages of tumor inception to subvert adaptive T cell immunity.

284 ) and IL-33 are consistently associated with adaptive Th2 immune responses in asthma.

285 When adaptive, the level of reproductive restraint is predict

286 cycles provides a path forward for multidrug adaptive therapy.

287 dvances provide a path forward for multidrug adaptive therapy.

288 Although this default response system may be adaptive, these hard-wired reactions can hinder the abil

289 SUV of 2.5 (SUV2.5), an SUV of 4.0 (SUV4.0), adaptive thresholding (A50P), 41% of SUV(max) (41%), a m

290 r experience violates our predictions, it is adaptive to upregulate encoding of novel information, wh

291 Consistency can make behavior an adaptive trait for mate choice decisions.

292 environmental cues, showing multidimensional adaptive trait syndromes.

293 rally plastic phenotype to produce a locally adaptive trait, but the role of plasticity for adaptive

294 to the maintenance of genetic variation and adaptive trajectories of rhizobia - and, potentially, ot

295 that complying with social norms has always adaptive value.

296 small populations without entirely swamping adaptive variation.

297 elling, a full account of rationalization as adaptive will need to account for the divergence in rati

298 ational Mouse Phenotyping Consortium (IMPC), adaptive windows were applied such that control data col

299 here is evidence to suggest that FLSs may be adaptive, with several competing hypotheses to explain t

300 t quantifying how the fitness of hundreds of adaptive yeast mutants responds to subtle environmental