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1 0.003 and p = 0.04, respectively, using the additive model).
2 nificance (P = 1.5 x 10(-13) for rs12777823, additive model).
3 ff above 60% coverage (p < 0.01; generalized additive models).
4 4.0%; celiac disease, 4.1%) beyond a simple additive model.
5 ubstantially better goodness of fit than the additive model.
6 ion single nucleotide polymorphisms using an additive model.
7 cancer risk allele for each SNP under a log-additive model.
8 using penalized splines within a generalized additive model.
9 deled baseline mortality using a generalized additive model.
10 ect cannot be approximated adequately by the additive model.
11 in ADCYAP1R1 (rs2267735) and asthma under an additive model.
12 34) after adjustment for covariates under an additive model.
13 trends, and day of week using a generalized additive model.
14 risk for a variant SNP allele based on a log-additive model.
15 d percent fat mass was investigated under an additive model.
16 ingle-nucleotide polymorphism (SNP) using an additive model.
17 dominant QTL that were not detectable by an additive model.
18 interval 1.10 to 1.56, P=0.002), assuming an additive model.
19 t PD (age > 59 years) were a recessive or an additive model.
20 e, generalized linear model, and generalized additive model.
21 variation for foliage and tuber blight on an additive model.
22 ts a significantly higher V (G) than does an additive model.
23 and 6 (MLS = 0.61 at 112.5 cM), all under an additive model.
24 locus and multiplicative models than for the additive model.
25 larger sample size to be detected under the additive model.
26 unterfactual emissions using the generalized additive model.
27 Data were fitted by multilevel generalized additive model.
28 ge deletions and total CNV burden support an additive model.
29 AAs; this relationship appears to follow an additive model.
30 .6 +/- 0.4 kJ/mol) when considering a simple additive model.
31 tion in soybean and function in line with an additive model.
32 t climates were examined using a generalized additive model.
33 ned using penalized splines within a general additive model.
34 assessed using log-linear analyses under an additive model.
35 an allelic model, with similar results in an additive model.
36 inations was analyzed by using a generalized additive model.
37 between each SNP and each phenotype under an additive model.
38 ctors than observations for both, linear and additive models.
39 ing stepwise model selection and generalized additive models.
40 , and half require more than five loci under additive models.
41 s, corresponding to dominant, recessive, and additive models.
42 bin transfusion thresholds using generalised additive models.
43 ariation between traits that are not seen in additive models.
44 logistic regression and binomial generalized additive models.
45 d to UKHSA, were estimated using generalised additive models.
46 in each city using overdispersed generalized additive models.
47 r combined exposures under multiplicative or additive models.
48 verlap for each population using generalized additive models.
49 using change-score analysis and generalized additive models.
50 covariate model with the aid of generalized additive modeling.
51 3.1 ms higher versus CC; 1-sided P=0.04) or additive model (0.06 SD [SE, 0.03] or 1.6 ms higher per
52 wide significance level [odds ratio (OR) for additive model = 1.61, 95%CI, 1.36-1.91, P = 3.2 x 10(-8
53 h overall HCC (odds ratio [OR] per G allele, additive model=1.77; 95% confidence interval [CI]: 1.42-
56 ducted separately in each sample assuming an additive model adjusted for age, sex and relatedness of
58 ing a quasi-Poisson hierarchical generalized additive model adjusted for population density and the C
60 s was performed on whites for each SNP in an additive model adjusting for baseline BP, age, sex, and
61 a combined meta-analysis under recessive and additive models after adjusting for age, sex, body mass
63 pared with a mutually exclusive approach, an additive model allowing for self-report of multiple iden
64 alence) using this marker were 1.37 under an additive model and 1.36 under a multiplicative model.
65 e statistical model based on the generalized additive model and allows for information sharing across
70 The results were analyzed using generalized additive models and logistic regression, adjusting for r
72 cal treatment were examined with generalized additive models and receiver operating characteristic an
75 homozygotes, assuming a multiplicative (log-additive) model and attributable fraction of 25% (95% CI
76 ded in an association analysis at 7 951 614 (additive model) and 4 669 537 (genotypic model) loci.
77 ), rs1581479 on 8p22 ($P=1.47\ast{10}^{-8}$, additive model) and rs73367537 on 10q26 ($P=1.21\ast{10}
79 m likelihood, crude and adjusted generalized additive models, and a machine learning approach based o
81 Partial Spearman's correlation, generalized additive models, and receiver operating characteristic (
82 hat of the two homozygotes); (2) 6 two-locus additive models; and (3) 16 two-locus heterogeneity mode
84 , and offspring survival and growth using an additive modelling approach on 21 years of individual-ba
85 Risk prediction evaluation identified the additive model as best for describing the effect of APOE
87 d linear model (NBGLM), Boosting generalized additive model (BGAM), Spline generalized additive model
89 the residual variances estimated by standard additive models can be inflated in the presence of G-C a
91 ein can identify cases where an independent, additive model cannot be applied and so require addition
92 tion (effective df = 3.83 in the generalized additive model, chi2 test P = .002 for the 4-df cubic sp
93 pared association tests based on a biallelic additive model constraining the effect of a single-nucle
95 h systolic and diastolic BP when a two-locus additive model developed for ACE concentration was used.
97 multivariable-adjusted logistic generalized additive model, elevated pathway-specific polygenic risk
99 s current strategies typically test only the additive model, exclude the X chromosome, and use only o
101 biomass burning, as detected by generalized additive models fitted to seven pollen and charcoal reco
102 ooled (P = 0.0010-0.00099) samples under the additive model, following correction for multiple testin
104 ve, which verifies the practice of using the additive model for analyzing SNP effects on metabolites.
105 ficients of the log-length correction in the additive model for arbitrary sequences and lengths and (
108 ting yeast growth rates, EFA outperforms the additive model for several traits with large epistasis h
109 th suggestive significance (P < 1E-5) in the additive model for the effect of the GxSex interaction o
115 demonstrate how one can use the generalized additive models for location, scale and shape (GAMLSS) d
116 e 'metamicrobiomeR' that applies Generalized Additive Models for Location, Scale and Shape (GAMLSS) w
117 ls, Generalised Additive Models, Generalised Additive Models for Location, Scale and Shape (GAMLSS),
119 ve models were constructed using Generalized Additive Models for Location, Scale, and Shape (GAMLSS)
124 mograms were estimated by use of generalized additive models for location, shape, and scale with Box-
126 s were detected following reanalysis with an additive model (for example, for birth weight, beta = 20
127 ear models (for climate PC1) and generalized additive models (for biology PC1-2) invoking only the cl
128 e introduce tradeSeq, a powerful generalized additive model framework based on the negative binomial
133 s; (3) a geographically weighted generalized additive model (GAM) ensemble model was used to fuse the
134 obal climate model, and create a generalized additive model (GAM) to examine how future changes in te
137 ic (ROC) curves and multivariate generalized additive model (GAM) were applied to predict outcomes.
139 At the first stage, we used a generalized additive model (GAM) with a Gaussian link to examine the
140 ver in two high-risk areas using Generalized Additive Model (GAM), random forests and Structural Equa
148 linear regression and nonlinear generalized additive models (GAMs) to estimate on-road concentration
149 were both linear and nonlinear, generalized additive models (GAMs) were chosen to model response cur
153 uding Generalised Linear Models, Generalised Additive Models, Generalised Additive Models for Locatio
154 y the same role) the predictions differ: the additive model has the same predictions as in the random
156 MELD >/=28 was higher than predicted by the additive model (HR=2.38, 95% CI 1.73-3.27, P<0.001) resu
158 anges in ACTN3 expression consistent with an additive model in the human genotype-tissue expression c
162 in cation/pi interactions is captured by an additive model in which the substituent is isolated from
164 plotype GC1s) was overtransmitted (P = 0.02, additive model) in the entire Boston cohort, in Whites (
166 was assessed by linear regression, using an additive model, in which absolute change in the Disease
175 uman skeletal muscle, but we suggest that an additive model is the most appropriate for use in testin
176 iome and mortality were determined using Cox additive models, Kaplan-Meier analysis, and Cox proporti
178 lues are factorized as a product between the additive model matrix and the h - 1 additive effects, an
179 e.g. maximum likelihood methods, generalized additive models, nonparametric kernel density estimators
180 ated with sCJD risk; within PRNP (rs1799990; additive model odds ratio [OR] 1.23 [95% CI 1.17-1.30],
181 CI], 1.82 to 3.26; P=1.42x10(-9); and in the additive model: odds ratio, 2.19; 95% CI, 1.66 to 2.90;
186 cell line-specific manner and that existing additive models of gene knockout effects fail at capturi
189 curve during an oral glucose tolerance test (additive model, P = 0.022; dominant model, P = 0.010).
190 R8 rs3764880-G (recessive model: p = 0.0173; additive model: p = 0.0161) were associated with pericar
191 cted mortality under medical treatment, with additive model predictive value (all, p </= 0.04) and a
198 ed additive model (BGAM), Spline generalized additive model (SGAM), Spike and slab regression (SSR),
210 ted SAR cases was analysed using generalized additive models, taking into account confounding factors
216 ndard deviations were detected; but under an additive model, these did not fully account for the obse
217 ical content on temperature is improved over additive models, though further sampling is required to
219 ral trends were analyzed using a Generalized Additive Model to capture the nonlinear dynamics effecti
220 lected outcome, the SLS used the generalized additive model to estimate locally averaged Omicron case
221 upancy model that uses a spatial generalized additive model to estimate non-linear spatial variation
224 ate holistic system indicator variables, non-additive modelling to estimate alternate attractors, and
225 rmed a retrospective study using generalized additive models to analyze three major livestock populat
229 x proportional hazard models and generalized additive models to examine multivariable-adjusted associ
231 of field observations in the North Sea with additive models to infer spatiotemporal trends of chloro
233 d gene coexpression networks and generalized additive models to predict effects on reproduction in th
234 s (generalized linear models and generalized additive models) to test environment-related hypotheses
235 rn North Atlantic Ocean based on generalized additive models, to establish a current habitat suitabil
237 lies on the use of Time-Varying Group Sparse Additive Models (TV-GroupSpAM) for high-dimensional, fun
239 (GxE), merits more involved models than the additive model typically used to analyze data from genom
241 7.5 million SNPs were examined under the log-additive model using Cox proportional hazards models, ad
242 ation studies on AWT were performed under an additive model using linear regression (adjusted for pac
243 d glaucoma was obtained with the generalized additive model using only three parameters (AROC = 0.854
244 est evidence of an FcgammaR-SLE association (additive model: V/V 176 versus V/F 176 OR 1.51, V/V 176
245 T. aestivum gene expression was compared to additive model values (mid-parent) calculated from paren
246 justed hazard ratio for each L allele in the additive model was 1.91 (1.20 to 3.06; P=0.01) for the r
247 ariance analysis indicated that a completely additive model was adequate to explain the variances obs
252 al multivariable regression with generalised additive models was used to investigate the effects of m
253 Using the same covariates in a generalized additive model, we examined the shape of the relationshi
254 s of 272 UM cases and 1782 controls using an additive model, we identified five variants significantl
255 tional GWAS of dominance deviations from the additive model, we identify no genome-wide-significant S
259 ographic and Health Surveys with generalized additive models, we quantify spatial patterns of measles
261 nfidence intervals) for each L allele in the additive model were 1.99 (1.27 to 3.14; P=0.003) for the
269 tivariate linear, piecewise, and generalized additive models were used to examine dose-response relat
274 nal study of 357 Yup'ik Eskimos, generalized additive models were used to plot covariate-adjusted ass
280 08 on 20p (location, chi = 19.5 cM) under an additive model, whereas the weighted MLS was 2.06 on 20q
283 polymorphisms (SNPs) and expression under an additive model, which ignores interaction and haplotypic
285 Cox proportional hazards regression under an additive model with adjustment for age at onset, sex, an
290 APOL1 risk alleles were associated under an additive model with systolic blood pressure (SBP) and ag
292 tistic is increased by >20%, on average, for additive models with modest genotype relative risks.
293 present study, the authors used generalized additive models with nonparametric smoothing splines to
294 d was not appropriate, we fitted generalised additive models with penalised splines to visualise tren
295 factorization and analyzed using generalized additive models with penalized splines to capture both l
296 ted to trait and state anxiety using general additive models with penalized splines, while controllin
299 Logistic regression models and generalized additive models with thin-plate splines were fit to the
300 using PLINK (logistic regression assuming an additive model) with sex, age, smoking and the first thr