ライフサイエンスコーパス: addressin

1 dhesion molecule-1 and peripheral lymph node addressin.

2 ion molecule-1 but not peripheral lymph node addressin.

3 ctin, L-selectin, VCAM-1, or peripheral node addressin.

4 (6-sulfo-sialyl Lewis x) on peripheral node addressin.

5 colocalization with peripheral node vascular addressin.

6 ted livers were positive for peripheral node addressin.

7 heterogeneous glycans termed peripheral node addressin.

8 tic lineage and express a well-characterized addressin.

9 that targets expression of mucosal vascular addressins.

10 roles of cytokines, chemokines, and vascular addressins.

11 hesion molecules VCAM, ICAM, peripheral node addressin (a marker of peripheral lymph nodes), and muco

12 tin with HEV-expressed peripheral lymph node addressin and by preferential interactions between CXCR2

13 aracterized by expression of peripheral node addressin and chemokine CCL21, is correlated with T-cell

14 lectin to bind to PSGL-1 and peripheral node addressin and explain in part the shorter lifetimes of P

15 ha4beta7 integrin (ie, peripheral lymph node addressin and mucosal addressin cell adhesion molecule-1

16 nstrated elimination of both peripheral node addressin and sialyl 6-sulfo Lewis X in high endothelial

17 nt of RAGE results in enhanced expression of addressins and it is therefore, not surprising that prev

18 ar segments displaying peripheral lymph node addressin, and the extravasation of lymphocytes to the o

19 The addressins are developmentally programmed to decorate en

20 ental switch occurs, and the peripheral node addressins are upregulated on high endothelial venules i

21 e that although Nkx2-3 activity controls the addressin balance of HEVs in GALT, the general HEV funct

22 yte homing receptors by B cells and vascular addressins by mucosal venules are similar in normal MALT

23 antibody (mAb) to VCAM-1 but not to mucosal addressin CAM-1 (MadCAM-1), recruitment of MCp's to the

24 there was variable expression of other skin addressins (CCR6, CCR10, and CLA).

25 The mucosal addressin cell adhesion molecule (MAdCAM) and vascular c

26 Mucosal addressin cell adhesion molecule (MAdCAM) binds integrin

27 phoid tissues through its binding to mucosal addressin cell adhesion molecule (MAdCAM), which is pres

28 Duodenal lymphocyte densities and mucosal addressin cell adhesion molecule (MAdCAM)-1 expression w

29 cell adhesion molecule (VCAM)-1, or mucosal addressin cell adhesion molecule (MadCAM)-1.

30 interaction with its primary ligand, mucosal addressin cell adhesion molecule (MAdCAM).

31 mic adhesion to recombinant mucosal vascular addressin cell adhesion molecule (MAdCAM-)1 in vitro as

32 ndothelial venules (HEVs) expressing mucosal addressin cell adhesion molecule (MAdCAM-1) and peripher

33 ell adhesion molecule-1 (VCAM-1) and mucosal addressin cell adhesion molecule (MAdCAM-1) on endotheli

34 Mucosal addressin cell adhesion molecule (MAdCAM-1) plays a pivo

35 on of mesenteric lymph node cells to mucosal addressin cell adhesion molecule (MAdCAM-1), the ligand

36 )beta(1), and their ligands mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1) and VCAM-1

37 n of alpha(4)beta(7) with its ligand mucosal addressin cell adhesion molecule 1 (MAdCAM-1) mediates h

38 ell adhesion molecule 1 (VCAM-1) and mucosal addressin cell adhesion molecule 1 (MadCAM-1) with IC50

39 ell as disruptions in positioning of mucosal addressin cell adhesion molecule 1 (MAdCAM-1)(+) sinus l

40 esion molecule (ICAM)-1, -2, and -3, mucosal addressin cell adhesion molecule 1 (MAdCAM-1), vascular

41 on molecule 1 (ICAM-1), and mucosal vascular addressin cell adhesion molecule 1 (MAdCAM-1), which cor

42 gene superfamily most reminiscent of mucosal addressin cell adhesion molecule 1 (MAdCAM-1).

43 are patterned to display dominantly mucosal addressin cell adhesion molecule 1 (MAdCAM-1).

44 Antibodies against mucosal vascular addressin cell adhesion molecule 1 (MADCAM1), which is c

45 ly mediated by interactions with the mucosal addressin cell adhesion molecule 1 and its lymphocyte li

46 ecule expression showed increases in mucosal addressin cell adhesion molecule 1 and vascular cell adh

47 ta7 and its vascular ligand mucosal vascular addressin cell adhesion molecule 1 are proving the value

48 Expression of the mucosal addressin cell adhesion molecule 1 during murine intesti

49 kade of peripheral node addressin or mucosal addressin cell adhesion molecule 1 failed to ameliorate

50 ession on DLN B cells, expression of mucosal addressin cell adhesion molecule 1 on the DLN high endot

51 hat activates alpha4beta7 binding to mucosal addressin cell adhesion molecule 1 on the hepatic endoth

52 ta7), and PF-00547659 (anti-mucosal vascular addressin cell adhesion molecule 1).

53 , the relative abundance of mucosal vascular addressin cell adhesion molecule 1-interacting (MAdCAM1-

54 o luminal contents but expressed the mucosal addressin cell adhesion molecule 1.

55 s of the mucosal vascular addressin, mucosal addressin cell adhesion molecule 1.

56 adelta T cell binding to recombinant mucosal addressin cell adhesion molecule 1.

57 l node addressin coexpressed on some mucosal addressin cell adhesion molecule 1.

58 Mucosal addressin cell adhesion molecule also stained HEVs and c

59 Mucosal addressin cell adhesion molecule blockade reduced Th1 re

60 olecule for T cells to enter mucosa, mucosal addressin cell adhesion molecule, is significantly incre

61 s in expression patterns of mucosal vascular addressin cell adhesion molecule-1 (MAdCAM-1) and T cell

62 the cell adhesion molecule mucosal vascular addressin cell adhesion molecule-1 (MAdCAM-1) and that R

63 adhesion of FDCP-mix to immobilized mucosal addressin cell adhesion molecule-1 (MAdCAM-1) and this w

64 in receptor, alpha 4 beta 7, and the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) are postul

65 Alpha 4 beta 7-mediated adhesion to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) directs ly

66 integrin promotes cell adherence to mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expressed

67 CD4/beta7+ population and increased mucosal addressin cell adhesion molecule-1 (MAdCAM-1) expression

68 Mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is an adhe

69 A related CAM, mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is recogni

70 In the mouse, mucosal addressin cell adhesion molecule-1 (MAdCAM-1) is selecti

71 oclonal antibody that binds to human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) to selecti

72 ha 4 beta 7 integrin and endothelial mucosal addressin cell adhesion molecule-1 (MAdCAM-1), adhesion

73 r cell adhesion molecule-1 (VCAM-1), mucosal addressin cell adhesion molecule-1 (MAdCAM-1), and E-sel

74 T sections were performed using anti-mucosal addressin cell adhesion molecule-1 (MAdCAM-1), anti-peri

75 The natural ligand for alpha4beta7, mucosal addressin cell adhesion molecule-1 (MAdCAM-1), bound eff

76 ntegrin that persistently adhered to mucosal addressin cell adhesion molecule-1 (MAdCAM-1), but also

77 The mucosal vascular addressin, mucosal addressin cell adhesion molecule-1 (MAdCAM-1), is an Ig

78 ing specificities for E-cadherin and mucosal addressin cell adhesion molecule-1 (MAdCAM-1), respectiv

79 In addition, we have shown that mucosal addressin cell adhesion molecule-1 (MAdCAM-1), the prima

80 l adhesion molecule-1, and muscosal vascular addressin cell adhesion molecule-1 (MAdCAM-1).

81 not tonsils or oral mucosa, express mucosal addressin cell adhesion molecule-1 (MAdCAM-1).

82 al mucosa; their respective ligands, mucosal addressin cell adhesion molecule-1 and CCL25, are displa

83 , resulting in increased adhesion to mucosal addressin cell adhesion molecule-1 and enhanced homing t

84 high endothelial venules coexpressed mucosal addressin cell adhesion molecule-1 and peripheral lymph

85 stimulated migration and adhesion to mucosal addressin cell adhesion molecule-1 and VCAM-1.

86 ining cells coexpress high levels of mucosal addressin cell adhesion molecule-1 and vimentin, indicat

87 a(4)beta(7) blocking Abs, but not to mucosal addressin cell adhesion molecule-1 blocking Abs.

88 lar cell adhesion molecule-1 and the mucosal addressin cell adhesion molecule-1 but not of other adhe

89 s in normal gastric mucosa expressed mucosal addressin cell adhesion molecule-1 but not peripheral ly

90 7 expression and enhanced binding to mucosal addressin cell adhesion molecule-1 in vitro while simult

91 n of migration by antibodies against mucosal addressin cell adhesion molecule-1 or alpha(4)beta(7) in

92 of the wild-type mice, expressed the mucosal addressin cell adhesion molecule-1 similar to the mesent

93 d adhesion to the alpha4beta7 ligand mucosal addressin cell adhesion molecule-1 under flow and locali

94 Mucosal addressin cell adhesion molecule-1 was not detected with

95 peripheral lymph node addressin and mucosal addressin cell adhesion molecule-1) also increased durin

96 of HUT-78 T cells and human PBLs to mucosal addressin cell adhesion molecule-1, a protein that is ex

97 beta7 mediates lymphocyte binding to mucosal addressin cell adhesion molecule-1, and its expression d

98 T cell alpha chemoattractant, CXCR5, mucosal addressin cell adhesion molecule-1, and VCAM-1 were up-r

99 rs (peripheral lymph node addressin, mucosal addressin cell adhesion molecule-1, LFA-1, ICAM-1, and V

100 Vascular endothelial expression of mucosal addressin cell adhesion molecule-1, the ligand that supp

101 nt lymphocyte binding to the ligands mucosal addressin cell adhesion molecule-1, VCAM-1 and CS1.

102 tested did not increase adhesion to mucosal addressin cell adhesion molecule-1.

103 rin on lymphocytes with the vascular mucosal addressin cell adhesion molecule-1.

104 ning connecting segment 1 (CS1), and mucosal addressin cell adhesion molecule-1.

105 heral node addressin (PNAd), but not mucosal addressin cell adhesion molecule-1.

106 ndependent of endothelial absence of mucosal addressin cell-adhesion molecule-1 (MAdCAM-1), which was

107 yer's patches (PP), display mucosal vascular addressin-cell adhesion molecule-1 (MAdCAM-1).

108 rker of peripheral lymph nodes), and mucosal addressin cellular adhesion molecule (a marker of mucosa

109 e adhesion molecules VCAM, ICAM, and mucosal addressin cellular adhesion molecule as well as the chem

110 ules VCAM, ICAM, E-selectin, and the mucosal addressin cellular adhesion molecule, MAdCAM-1.

111 , was developed specifically to bind mucosal addressin cellular adhesion molecule-1 (MAdCAM-1), a muc

112 raction of alpha4beta7 integrin with mucosal addressin cellular adhesion molecule-1 (MAdCAM-1).

113 of CD69, and high levels of the skin-homing addressins CLA, CCR4, and CCR6.

114 in (L-Sel) interactions with peripheral node addressin coexpressed on some mucosal addressin cell adh

115 ssed by infiltrating T cells and endothelial addressins displayed on local vasculature were character

116 adhesion receptors including peripheral node addressin, E-, L-selectin and Mac-1 but not P-selectin o

117 unoglobulin family and carbohydrate vascular addressins encoded by Madcam1 and St6gal1 control lympho

118 oming by facilitating lymphocyte adhesion to addressins expressed in the high endothelial venules (HE

119 This switch in addressin expression facilitates tissue-selective lympho

120 ined lymphocyte homing receptor and vascular addressin expression in a case of primary gastric B-cell

121 ial COUP-TFII overexpression induces ectopic addressin expression in NKX2-3(+) capillaries, while NKX

122 ) lymphoreticular cells, and peripheral node addressin(+) HEVs.

123 NALT of Cxcl13(-/-) mice has peripheral node addressin(+) high endothelial venules (HEVs).

124 inhibited by monoclonal antibody to mucosal addressin in a regionally specific manner with greatest

125 e intestine and investigate the role of this addressin in recirculation of mononuclear cells.

126 The mucosal vascular addressin is expressed early in ontogeny and can be dete

127 r cell adhesion molecule (VCAM)-1 or mucosal addressin (MAd)CAM-1 to support eosinophil rolling or fi

128 dominant adhesion molecules are the mucosal addressin MAdCAM-1 on lymph node high endothelial venule

129 uch as the loss in expression of the mucosal addressin MAdCAM-1, whose counter receptor a4beta7 on ly

130 ough induction of chemokines and the mucosal addressin MAdCAM-1.

131 orresponded with adhesion to the gut mucosal addressin, MAdCAM-1, in vitro.

132 The mucosal vascular addressin, MAdCAM-1, is an Ig family adhesion receptor p

133 riggers IELp binding to the mucosal vascular addressin MAdCAM1.

134 2 chain and impaired expression of a mucosal addressin marker on sinus-lining cells.

135 xpressed high levels of the mucosal vascular addressin, mucosal addressin cell adhesion molecule 1.

136 The mucosal vascular addressin, mucosal addressin cell adhesion molecule-1 (M

137 le adhesion receptors (peripheral lymph node addressin, mucosal addressin cell adhesion molecule-1, L

138 no change in expression of the local MAdCAM addressin, no VCAM induction, no histologically detectab

139 ecule on leukocytes binds to peripheral node addressin on high endothelial venules of lymph nodes to

140 on lymphocytes and the peripheral lymph node addressins on specialized high endothelial venules.

141 Immunoblockade of peripheral node addressin or mucosal addressin cell adhesion molecule 1

142 sed levels of mRNA for peripheral lymph node addressin (PNAd) backbone proteins as well as enhanced e

143 e with reduced expression of peripheral node addressin (PNAd) explained by a severe reduction in the

144 volves L-selectin binding to peripheral node addressin (PNAd) on HEVs.

145 on other leukocytes and with peripheral node addressin (PNAd) on high endothelial venules.

146 h de novo synthesis of peripheral lymph node addressin (PNAd) presented on high-endothelial venule (H

147 t not uninfected skin, while peripheral node addressin (PNAd) was minimally expressed in all samples.

148 ng on P-, E-, L-selectin, or peripheral node addressin (PNAd) were compared at estimated single bond

149 cell proliferation, although peripheral node addressin (PNAd)(+) endothelial cells are less sensitive

150 -selectin on lymphocytes and peripheral node addressin (PNAd), a set of sialomucins displayed on high

151 molecule-1 (MAdCAM-1), anti-peripheral node addressin (PNAd), and anti-VCAM-1 mAbs.

152 on molecule (VCAM)-1 and the peripheral node addressin (PNAd), but not mucosal addressin cell adhesio

153 ollectively termed the peripheral lymph node addressin (PNAd), have been shown to contain fucose, sia

154 sion molecule (MAdCAM-1) and peripheral node addressin (PNAd), ligands for naive cell entrance into L

155 rized by the development of peripheral nodal addressin (PNAd)-expressing high endothelial venules and

156 tic cell networks, and peripheral lymph node addressin (PNAd)-positive high endothelial venules (HEVs

157 al for expression of luminal peripheral node addressin (PNAd)], and PNAd itself.

158 hesion through L-selectin to peripheral node addressin (PNAd, also known as MECA-79 antigen), an L-se

159 these cytokines induced the peripheral node addressin, PNAd.

160 with DCs, the appearance of peripheral-node addressin-positive (PNAd+) vessels, and production of ch

161 rs are in close proximity to peripheral node addressin-positive cells and contain cells positive for

162 reas, namely the presence of peripheral node addressin-positive structures, C-X-C motif chemokine lig

163 ches in mice through determining endothelial addressin preference and may function as a susceptibilit

164 Peripheral node addressin recognized by the MECA-79 antibody is apparent

165 Peripheral node addressin represents a class of L-selectin ligands recog

166 t was to study the expression of the mucosal addressin required for Peyer's patch-selective lymphocyt

167 may also participate; however, the vascular addressins, required for homing to peripheral and mucosa

168 To investigate the addressins responsible for naive lymphocyte binding, imm

169 cent staining for the corresponding vascular addressins revealed intense expression of VCAM-1 on smal

170 equired for the induction of peripheral node addressin that may contribute to the recruitment of L-se

171 nasal mucosal immunity, we investigated the addressins that allow for lymphocyte trafficking to this

172 r progenitor cells analogous to the vascular addressins that direct selective lymphocyte homing to ly

173 of L-selectin ligands (peripheral lymph node addressins) together with ICAM-1 and SLC.

174 molecule-1 (MAdCAM-1), a mucosal-restricted addressin up-regulated during gut inflammation.

175 with dramatic up-regulation of the vascular addressin, VCAM, a vigorous mixed-cell inflammatory resp

176 ial venules expressing peripheral lymph node addressin were frequently observed in the thyroid tissue