ライフサイエンスコーパス: adeno-associated virus vector

1 interference (RNAi) cassette delivered by an adeno-associated virus vector.

2 nly in hepatocytes, due to infection with an adeno-associated virus vector.

3 oloney murine leukemia virus, adenovirus, or adeno-associated virus vector.

4 28-fold that obtained using single-stranded adeno-associated virus vectors.

5 blastic cells using herpes simplex virus and adeno-associated virus vectors.

6 livered to injured heart tissue by different adeno-associated virus vectors.

7 assemblies, similar to the best recombinant adeno-associated virus vectors.

8 med m.11778G>A mutation, using a recombinant adeno-associated virus vector 2, serotype 2 (rAAV2/2-ND4

9 ty and tolerability of escalated doses of an adeno-associated virus vector (AAV) expressing a normal

10 We used a recombinant adeno-associated virus vector (AAV) to deliver a foreign

11 Recombinant adeno-associated virus vectors (AAV) were prepared in hi

12 The RNAi trigger, expressed from adeno-associated virus vectors (AAV.miS1), also correcte

13 es simplex virus vector, HSV.CMVlac, and the adeno-associated virus vector, AAV.CMVlac, is affected b

14 very of anti-N-terminal htt scFv-C4 using an adeno-associated virus vector (AAV2/1) significantly red

15 An adeno-associated virus vector (AAV9) for alpha-synuclein

16 protein tau to the substantia nigra using an adeno-associated virus vector (AAV9).

17 Apart from their therapeutic potential, adeno-associated virus vectors also represent outstandin

18 cus aureus) and guide RNA constructs into an adeno-associated virus vector and systemically delivered

19 sfer by nonspecifically bound adenovirus and adeno-associated virus vectors and by a modified adenovi

20 A candidate was overexpressed in hearts with adeno-associated virus vectors and inhibited with antise

21 either singly or in combination by employing adeno-associated virus vectors and then challenged with

22 Using retrograde adeno-associated virus vectors and transgenic mice expre

23 ession of IkappaBzeta in hepatocytes via the adeno-associated virus vector attenuated liver steatosis

24 Recombinant adeno-associated virus vectors based on serotype 2 (rAAV

25 Recombinant adeno-associated virus vectors based on serotype 6 (rAAV

26 erapy approach for Alzheimer's disease using adeno-associated virus vector-based knockdown of CD33 re

27 n delivered in a single, clinically relevant adeno-associated virus vector, can support functional im

28 encies in vivo, we constructed a recombinant adeno-associated virus vector carrying the NDI1 gene (rA

29 Administration of rTMD1 or recombinant adeno-associated virus vector carrying TMD1 could be a p

30 Intrahippocampal injections of adeno-associated virus vectors containing the astrocyte-

31 the use of a dominant-negative forkhead boxO adeno-associated virus vector delivered directly to the

32 Importantly, adeno-associated virus vector-delivered homodimeric mini

33 We used adeno-associated virus vector-delivered siRNAs to select

34 novel treatment strategy with a recombinant adeno-associated virus vector delivering a modified FVII

35 ive vaccination strategy whereby recombinant adeno-associated virus vectored delivery of anti-prion s

36 Intrathecally delivering an adeno-associated virus vector encoding an RfxCas13d vari

37 A recombinant adeno-associated virus vector encoding human delta-sarco

38 therapy of CML, we constructed a recombinant adeno-associated virus vector encoding the p210(BCR-ABL)

39 xpression system, we generated a recombinant adeno-associated virus vector encoding the VEGFR2-neutra

40 -infected rhesus macaques (RMs) treated with adeno-associated virus vectors encoding eCD4-Ig.

41 r the use of DCs transduced with recombinant adeno-associated virus vectors encoding multiepitope imm

42 developed adult brain, we have generated an adeno-associated virus vector expressing a small hairpin

43 was obtained by stereotaxic injection of an adeno-associated virus vector expressing Cre recombinase

44 ingle intraportal injection of a recombinant adeno-associated virus vector expressing factor IX succe

45 Administration of a self-complementary Adeno-Associated Virus vector expressing full-length SMN

46 We transduced NAcore astrocytes with an adeno-associated virus vector expressing hM3D designer r

47 directed gene therapy with a single-stranded adeno-associated virus vector expressing human Factor IX

48 uring early AD-like pathology, a recombinant adeno-associated virus vector expressing TNF-alpha was s

49 Here, we report an adeno-associated virus vector expressing Txnip, which pr

50 proach to assess the efficacy of recombinant adeno-associated virus vectors expressing inducible IL-2

51 t NOD scid gamma (NSG) mice by the use of an adeno-associated virus vector, followed by engraftment o

52 is compact enough to be packaged in a single adeno-associated virus vector for persistent in vivo gen

53 ng to minimize its size to fit into a single adeno-associated-virus vector for future application.

54 latory system involving a single recombinant adeno-associated virus vector harboring two expression c

55 atory elements in the context of recombinant adeno-associated virus vectors has enabled cell-type-res

56 we show that expression of these genes from adeno-associated virus vectors in C57BL/6 mice is able t

57 SG -( K(b) D(b)) (null) ( IA(null)) mice via adeno-associated virus vector increased human CD45(+) ce

58 Clenbuterol along with a low-dose adeno-associated virus vector increased Rotarod latency

59 the nuclei of retinal ganglion cells via an adeno-associated virus vector injected into the vitreous

60 e correction mediated by a limited number of adeno-associated virus vector injections in the cat mode

61 Genomic integration of the adeno-associated virus vector into Cas9 target sites cau

62 he NFAT inhibitor VIVIT to astrocytes, using adeno-associated virus vectors, led to reduced GFAP prom

63 These observations suggest that adeno-associated virus vectors may be used to modify tro

64 Finally, we tested adeno-associated virus vector-mediated ABCD1 delivery to

65 We tested the hypothesis that adeno-associated virus vector-mediated delivery of the h

66 demonstrate that a combined adeno virus and adeno-associated virus vector-mediated gene transfer lea

67 deletion of the cannabinoid receptor-1 or by adeno-associated virus vector-mediated silencing of astr

68 gnaling in a common mouse model of AD, using adeno-associated virus vectors normalized glutamate sign

69 The potential therapeutic, adeno-associated virus vector of serotype rh.74 (AAVrh.7

70 d, we have generated a series of recombinant adeno-associated virus vectors of serotypes 1 and 5 enco

71 ing co-injection of two separate recombinant adeno-associated virus vectors, one encoding an inducibl

72 A mixture of two adeno-associated virus vectors, one expressing the trans

73 This is achieved using a specialized adeno-associated virus vector optimized for the producti

74 ing either gene replacement strategies using adeno-associated virus vectors or gene editing strategie

75 We introduced recombinant adeno-associated virus vector (rAAV) carrying a lacZ rep

76 Recombinant adeno-associated virus vector (rAAV) incorporating a con

77 Recombinant adeno-associated virus vectors (rAAV) show promise in pr

78 tically enhances transduction by recombinant adeno-associated virus vectors (rAAV).

79 through delivery of a serotype-1 recombinant adeno-associated virus vector (rAAV1-IFNgamma).

80 receptor retargeting.IMPORTANCE Recombinant adeno-associated virus vectors (rAAVs), based on AAV8 an

81 F21 by administration of an FGF21-expressing adeno-associated virus vector recapitulated these compli

82 yte-selective overexpression of p21 using an adeno-associated virus vector reduced long-term patholog

83 acerebral administration of a Ngb-expressing adeno-associated virus vector reduces infarct size and i

84 mophilia A in dogs, and that double-stranded adeno-associated virus vectors resulted in expression of

85 of mice, by using a replication-incompetent adeno-associated virus vector, results in tumours with a

86 human patients, and gene augmentation using adeno-associated virus vectors robustly sustained the re

87 ubpial dorsal horn-targeted delivery of AAV (adeno-associated virus) vector(s) encoding GABA (gamma-a

88 Furthermore, when delivered via dual adeno-associated virus vectors, sABE can efficiently con

89 Direct putaminal infusion of adeno-associated virus vector (serotype 2) (AAV2) contai

90 Intravascular injection of certain adeno-associated virus vector serotypes can cross the bl

91 In contrast to other gene delivery systems, adeno-associated virus vectors show long term gene expre

92 liver as a key target for gene therapy, with adeno-associated virus vectors showing long-term effecti

93 In vivo knockdown of IFITM1 using an AAV (adeno-associated virus) vector significantly attenuated

94 A recombinant Adeno Associated Virus vector targeting the Albumin locu

95 ts within the packaging limit of recombinant adeno-associated virus vectors that have been shown to b

96 timized parameters and methods for injecting adeno-associated virus vectors through the cranial imagi

97 We used an adeno-associated virus vector to achieve targeted insert

98 acerebral antibody delivery, we developed an adeno-associated virus vector to drive neuronal expressi

99 -deleted factor VIII coding sequence with an adeno-associated virus vector to prevent bleeding in per

100 Here, we have used adeno-associated virus vectors to disrupt dominant-negat

101 The use of adeno-associated virus vectors to express short-hairpin

102 nzymatically inactive HEXA(R178H) mutant, or adeno-associated virus vectors to induce hepatocyte-spec

103 Delivery of this isoform using a recombinant adeno-associated virus vector type 9 resulted in amelior

104 Using an inducible recombinant adeno-associated virus vector, we investigated the effec

105 Here we compare the effects of adeno-associated virus vectors with neurotrophin gene in

106 o circumvent this toxicity, we developed new adeno-associated virus vectors with skeletal muscle-rest

107 review the main molecular characteristics of adeno-associated virus vectors, with a particular view t