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1 e effects found for exogenously administered adenosine agonists.
2 eta, IL-6, and IL-8 mRNA were not changed by adenosine agonists.
4 bstituted adenosines designed from the A(2B) adenosine agonist 4 were synthesized and their A(2B)R po
6 ulated with IL-1 and either the nonselective adenosine agonist 5'-N-ethylcarboxamidoadenosine (NECA)
8 f this study was to determine the effects of adenosine agonists and an antagonist on ischemia-induced
14 osine receptor agonist NECA but not the A(1)-adenosine agonist CCPA replicated the adenosine effect.
15 These effects were reproduced by using the adenosine agonist CGS 21680 and were counteracted with t
18 hod for determining specificity of synthetic adenosine agonist compounds for the A2A and A2B receptor
21 liquid culture gave ED50 values for various adenosine agonists consistent with reported Kd alpha val
23 Adenosine and dipyridamole are nonselective adenosine agonists currently used as pharmacologic stres
26 alent linking of functionalized congeners of adenosine agonists, each being selective for either the
27 highlights the potential therapeutic use of adenosine agonists for treating autoimmune diseases invo
28 While simple carbocyclic substitution of adenosine agonists greatly diminishes potency, methanoca
30 affinity of ribose-containing ligands (i.e., adenosine agonists) have been identified in both TM3 and
32 of Gly-14 in TM1 to Thr-14, the affinity for adenosine agonists increased 100-fold, and after Pro-25
33 ylate (BTH4, 7; Figure 1), which antagonized adenosine agonist-induced inhibition of adenylyl cyclase
35 with a KB value of 1.62 +/- 0.73 microM and adenosine agonist-induced stimulation of adenylyl cyclas
38 timulated CGRP release and suggest that A(1) adenosine agonists may warrant further investigation in
39 erebellar administration of the A1-selective adenosine agonist, N6-cyclohexyladenosine (CHA) on ethan
41 receptor transcripts, only the nonselective adenosine agonist NECA (5'-N-ethylcarboxamidoadenosine),
43 Activation of the current by serotonin and adenosine agonists occurred with a time constant of 200-
47 (-7) M), but only in the presence of PIA, an adenosine agonist that inhibits the cyclic AMP pathway.