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1 eotides (particularly adenosine triphosphate/adenosine diphosphate).
2 specifically binds guanosine diphosphate and adenosine diphosphate.
3 sue injury and sensitization of platelets to adenosine diphosphate.
4 secretion induced by thrombin, collagen, and adenosine diphosphate.
5 needed to undock the neck linker and release adenosine diphosphate.
6 on and higher ex vivo platelet reactivity to adenosine diphosphate.
7 ctivated receptor (PAR) agonists, but not by adenosine diphosphate.
8 hosphorylation to adenosine triphosphate and adenosine diphosphate.
9 ntly as (3)H-adenosine triphosphate and (3)H-adenosine diphosphate.
10 when aggregation was induced by 5 mumol/l of adenosine diphosphate.
11 d in complex with a pair of products TPP and adenosine diphosphate.
12 oms resolution in complex with magnesium and adenosine diphosphate.
13 tance aggregometry in response to 20 mumol/L adenosine diphosphate.
14 cell fluorescence similar to that induced by adenosine diphosphate (10 muM) or thrombin (1 U/mL).
15 light transmittance aggregometry responses (adenosine diphosphate 20 muM) post-maintenance dose were
16 ers were defined by a relative inhibition of adenosine diphosphate (20 micromol/L)-induced platelet a
17 onstrated impaired microvessel relaxation to adenosine diphosphate (29+/-3% versus 61+/-6%, CHOL vers
18 ts [PRU]), light transmittance aggregometry (adenosine diphosphate 5 and 20 mumol/l and arachidonic a
20 mbranes but is recruited to molecularly aged adenosine diphosphate actin filaments and is necessary f
23 termined after incubation with ATP (5 mM) or adenosine diphosphate (ADP) (5 mM) with or without 15 mi
24 ed greater platelet aggregation to 5-mumol/l adenosine diphosphate (ADP) (50.7 +/- 16.4% vs. 34.2 +/-
25 not reflected in corresponding increases in adenosine diphosphate (ADP) and adenosine monophosphate
26 osine triphosphate (ATP) and its precursors, adenosine diphosphate (ADP) and adenosine monophosphate
27 esponses stimulated by weak agonists such as adenosine diphosphate (ADP) and adrenaline were severely
28 tivity by optical platelet aggregation using adenosine diphosphate (ADP) and arachidonic acid (AA).
29 Light transmittance aggregation induced by adenosine diphosphate (ADP) and arachidonic acid, total
31 g PI3Kgamma disaggregated following low-dose adenosine diphosphate (ADP) and had a mildly impaired ab
32 MRS showed trends for more rapid calculated adenosine diphosphate (ADP) and phosphocreatine (PCr) re
34 n or CRP, whereas they aggregate normally to adenosine diphosphate (ADP) and spread on fibrinogen.
35 b was measured with and without low and high adenosine diphosphate (ADP) and thrombin receptor activa
36 ce of low levels of primary agonists such as adenosine diphosphate (ADP) and thrombin, or others like
37 of the platelet P2Y12 receptor (P2Y12R) for adenosine diphosphate (ADP) are associated with increase
41 pendence of the adenosine triphosphate (ATP)/adenosine diphosphate (ADP) exchange rates of F(1)-ATPas
43 ownregulate the adenosine triphosphate (ATP)/adenosine diphosphate (ADP) metabolite ratio which stron
44 exhibiting heightened platelet reactivity to adenosine diphosphate (ADP) might be at increased risk f
45 high-resolution structure revealed that the adenosine diphosphate (ADP) moiety of the FAD prosthetic
46 effect of adenosine monophosphate (AMP) and adenosine diphosphate (ADP) on flagellar beating is not
47 ng to alphaIIbbeta3 following stimulation by adenosine diphosphate (ADP) or protease-activated recept
48 venous cangrelor, a rapid-acting, reversible adenosine diphosphate (ADP) receptor antagonist, might r
49 n-coupled nucleotide receptors: the platelet adenosine diphosphate (ADP) receptor coupled to stimulat
51 abolite that inhibits the platelet P2Y(1)(2) adenosine diphosphate (ADP) receptor, decreasing platele
52 wn regulator that operates downstream of the adenosine diphosphate (ADP) receptor, P2Y12, a target of
53 m in thrombus formation: the coinhibition of adenosine diphosphate (ADP) receptors with collagen rece
54 ht chain (RLC) phosphorylation and strain on adenosine diphosphate (ADP) release from cross-bridges i
58 g either 2), inorganic phosphate (Pi) or 3), adenosine diphosphate (ADP) to the motility solutions.
59 lonyl-CoA, adenosine triphosphate (ATP), and adenosine diphosphate (ADP) were separated by capillary
60 ic rats to eNOS-dependent (acetylcholine and adenosine diphosphate (ADP)) and -independent (nitroglyc
61 sphate (ATP) and its first five catabolites: adenosine diphosphate (ADP), adenosine monophosphate (AM
63 ergy including adenosine triphosphate (ATP), adenosine diphosphate (ADP), and adenosine monophosphate
64 vity assay, measuring platelet reactivity to adenosine diphosphate (ADP), convulxin (CVX), and thromb
65 early GPIb-IX signaling independent of Syk, adenosine diphosphate (ADP), or thromboxane A2 (TXA2), i
66 ity towards ATP and is strongly inhibited by adenosine diphosphate (ADP), we asked how Hsp104 functio
67 elet homeostasis and allow responsiveness to adenosine diphosphate (ADP), we developed a computationa
68 tructural ensembles for p47-p97 complexes in adenosine diphosphate (ADP)- and adenosine triphosphate
69 enzeneacetamide methanesulfonate), inhibited adenosine diphosphate (ADP)-, 2-methylthioADP (2-MeSADP)
71 ity for Tim44, as well as through release of adenosine diphosphate (ADP)-bound mtHsp70 from Tim44 by
72 to demonstrate that ATP-bound Rok1, but not adenosine diphosphate (ADP)-bound Rok1, stabilizes Rrp5
73 electron microscopy (cryo-EM) structures for adenosine diphosphate (ADP)-bound, full-length, hexameri
74 utaneous coronary intervention by inhibiting adenosine diphosphate (ADP)-dependent platelet activatio
75 analyzer-ASA score > or = 550, 5 micromol/l adenosine diphosphate (ADP)-induced aggregation > or = 7
80 he rapid and robust synthesis of polymers of adenosine diphosphate (ADP)-ribose (PAR) chains, primari
81 he MERS-CoV macro domain as a more efficient adenosine diphosphate (ADP)-ribose binding module than m
82 e find that puffs acquire elevated levels of adenosine diphosphate (ADP)-ribose modified proteins and
84 e that SIRT6 physically associates with poly[adenosine diphosphate (ADP)-ribose] polymerase 1 (PARP1)
86 with ER stress, we found elevated levels of adenosine diphosphate (ADP)-ribosylated BiP in the inact
88 io]triphosphate (GTP gamma S) stimulation of adenosine diphosphate (ADP)-ribosylation factor (ARF) an
91 c translation elongation factor 2 (eEF2) via adenosine diphosphate (ADP)-ribosylation of a modified h
93 denosine antibodies were used to detect ecto-adenosine diphosphate (ADP)-ribosyltransferase (ART) act
103 ellular AMP:adenosine triphosphate (ATP) and adenosine diphosphate (ADP):ATP ratios and balancing the
104 lease associated with main power stroke) and adenosine diphosphate (ADP, release associated with mino
105 endent signaling (e.g., by sirtuins and poly-adenosine diphosphate [ADP] ribose polymerases [PARPs])
106 sed using agonists specific (6 and 20 microM adenosine diphosphate [ADP]) and nonspecific (6 microg/m
107 f p21, caspase cascade activation, and poly (adenosine diphosphate [ADP]) ribose (PARP) cleavage.
109 ation, cleavage of caspase 3, and PARP (poly-adenosine diphosphate [ADP]-ribose polymerase), and incr
111 ith DNA-repair defects would respond to poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) in
113 ent study investigated the potential of poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP-1)
115 tion by pan-caspase inhibitor abolished poly(adenosine diphosphate [ADP]-ribose) polymerase cleavage
116 on of caspases-8 and -3 and cleavage of poly(adenosine diphosphate [ADP]-ribose) polymerase following
118 positive staining for nitrotyrosine and poly(adenosine diphosphate [ADP]-ribose) polymerase-1 (PARP-1
122 etic cofactors (adenosine triphosphate [ATP]/adenosine diphosphate [ADP]/adenosine monophosphate [AMP
124 lephrine group with significant increases in adenosine diphosphate and adenosine monophosphate and no
125 lets responded in a dose-dependent manner to adenosine diphosphate and protease-activating peptide (P
126 trapped not ATP, but the reaction products, adenosine diphosphate and the phosphorylated RIIbeta sub
129 d with variation in the platelet response to adenosine diphosphate and/or the collagen-mimetic peptid
131 structure of MsbA in complex with magnesium, adenosine diphosphate, and inorganic vanadate (Mg.ADP.Vi
132 owing stimuli to arachidonic acid, collagen, adenosine diphosphate, and thrombin as secondary endpoin
133 mal platelet aggregation to 5 and 20 mumol/l adenosine diphosphate, and VerifyNow P2Y12 platelet resp
136 d stronger platelet inhibition than ASA with adenosine diphosphate as the agonist, and combination th
137 pyrase (CD39 converts adenosine triphosphate/adenosine diphosphate [ATP/ADP] to adenosine monophospha
139 migration of primary microglial cells toward adenosine diphosphate by 257, 247, 301, 394, and 345% fo
140 n/epinephrine agonist cartridge and collagen/adenosine diphosphate (CADP) agonist cartridge, VerifyNo
141 by platelet aggregation to arachidonic acid, adenosine diphosphate, collagen and epinephrine, Platele
144 r the addition of glutamate and malate (GM), adenosine diphosphate (d), succinate (S) and octanoyl ca
145 High on-treatment platelet reactivity to adenosine diphosphate during clopidogrel therapy is a we
146 ed platelet aggregation to arachidonic acid, adenosine diphosphate, epinephrine, and platelet functio
147 e redox potential and adenosine triphosphate/adenosine diphosphate failed to reach a new steady state
148 : ATP, phosphocreatine, inorganic phosphate, adenosine diphosphate, Gibbs free energy of ATP hydrolys
149 lso exhibited activity towards quercetin and adenosine diphosphate glucose (ADPG), kaempferol and UDP
151 ransgenic reports point to the importance of adenosine diphosphate glucose pyrophosphorylase in contr
152 transferase (GT) that transfers glucose from adenosine diphosphate glucose to a glucan chain acceptor
153 e >> 5'adenosine-triphosphate (ATP) > or = 5'adenosine-diphosphate > 5'uridine-triphosphate > or = 5'
154 Poly(ADP-ribose) polymerase-1 (PARP-1) (ADP, adenosine diphosphate) has a modular domain architecture
155 ency, exhibit limited adenosine triphosphate/adenosine diphosphate hydrolysis activity, and fail to s
156 are lacking for PARG, the specific inhibitor adenosine diphosphate (hydroxymethyl)pyrrolidinediol (AD
157 omain is protected from dephosphorylation by adenosine diphosphate in the complete absence of the bet
160 bolished the 3-fold prolongation in collagen adenosine diphosphate-induced closure times seen in exte
161 reactivity was increased when measured using adenosine diphosphate-induced light transmission aggrego
165 e (AppCHClppA) are competitive inhibitors of adenosine diphosphate-induced platelet aggregation, whic
166 edly lower PR at all times (5- and 20-microM adenosine diphosphate-induced, and 15- and 25-microM thr
168 creatine kinase catalyzed phosphorylation of adenosine diphosphate is examined in two independent ser
169 cteroids, thus indicating that extracellular adenosine diphosphate is important during nodulation.
171 in intramuscular inorganic phosphate, H(+) , adenosine diphosphate, lactate and phosphocreatine deple
173 let aggregation and degranulation induced by adenosine diphosphate or collagen were diminished but we
174 ns diminished channel responses to magnesium adenosine diphosphate or diazoxide, while dominant KCNJ1
175 n vitro stimulation of PT-VWD platelets with adenosine diphosphate or thrombin demonstrates a signifi
179 predicted aggregation to 2 muM and 10 muM of adenosine diphosphate (P = .02 and <.001, respectively)
181 ctivity, especially with tests measuring the adenosine diphosphate-P2Y12 receptor pathway, without si
182 chondrial inner membrane, thereby uncoupling adenosine diphosphate phosphorylation from nutrient oxid
183 caspase activation and the cleavage of poly(adenosine diphosphate) (poly(ADP)) ribose polymerase.
186 ficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, with clopidog
187 severity of the disease, early treatment of adenosine diphosphate receptor antagonists at presentati
188 rials are needed to define the role of newer adenosine diphosphate receptor antagonists in this setti
195 nction testing to guide choice and dosing of adenosine diphosphate receptor inhibitor (ADPri) therapy
196 This study used data from the Treatment With Adenosine Diphosphate Receptor Inhibitors-Longitudinal A
197 2365 patients enrolled in the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal
199 d States TRANSLATE-ACS study (Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal
200 ive from 233 hospitals in the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal
203 cleotide exchange factor CalDAG-GEFI and the adenosine diphosphate receptor P2Y12 as independent path
204 ivation of integrin alphaIIbbeta3, while the adenosine diphosphate receptor P2Y12, the target for ant
206 the availability of rapidly-acting platelet adenosine diphosphate-receptor antagonists, the need for
207 isolated terminals, we tested 8-bromo-cyclic adenosine diphosphate ribose (8Br-cADPr), a competitive
208 ribosyltransferases catalyze the transfer of adenosine diphosphate ribose (ADP-ribose) from nicotinam
209 brane protein that converts NAD primarily to adenosine diphosphate ribose (ADPR) and a small amount o
212 where, involves the release of mitochondrial adenosine diphosphate ribose (ADPR) or nicotinamide aden
214 f two potent Ca(2+) releasing agents: cyclic adenosine diphosphate ribose (cADPR) from nicotinamide a
215 of the calcium-mobilizing metabolite, cyclic adenosine diphosphate ribose (cADPR), from nicotinamide
216 osal mast cells through an IL-13-CD38-cyclic adenosine diphosphate ribose (cADPR)-dependent process.
222 ng agents sphingosine-1-phosphate and cyclic adenosine diphosphate ribose exhibited weaker ABA-stimul
223 is a calcium-permeable channel activated by adenosine diphosphate ribose metabolites and oxidative s
224 accompanied by caspase-3 activation and poly-adenosine diphosphate ribose polymerase (PARP) cleavage
225 age during transplantation can activate poly-adenosine diphosphate ribose polymerase (PARP) resulting
226 ial growth factor, 3-nitrotyrosine, and poly(adenosine diphosphate ribose) expression in lung tissue.
227 NBC has rationalized clinical trials of poly(adenosine diphosphate ribose) polymerase (PARP) inhibito
229 wn or putative radiosensitizers such as poly(adenosine diphosphate ribose) polymerase and mammalian-t
230 ired IHHs displayed caspase activation, poly(adenosine diphosphate ribose) polymerase cleavage, and a
231 In cells deficient in the telomeric poly(adenosine diphosphate ribose) polymerase tankyrase 1, si
232 entification of an unexpected molecule, poly(adenosine diphosphate ribose), that may be implicated in
233 ATR), DNA-dependent protein kinase, and poly[adenosine diphosphate ribose] polymerase (PARP) 1/2.
234 on stress, a defect accentuated by poly-ADP (adenosine diphosphate) ribose polymerase inhibitors.
237 PM2 channels were activated by intracellular adenosine diphosphate-ribose and blocked by flufenamic a
238 rial dysfunction, caspase cleavage, and poly adenosine diphosphate-ribose polymerase (PARP) degradati
240 ROS), 3-nitrotyrosine (marker of RNS), poly(adenosine diphosphate-ribose) (PAR, marker of PARP activ
241 noblots demonstrated adaphostin induced poly(adenosine diphosphate-ribose) polymerase (PARP) cleavage
242 ected by caspases-3 and -8 cleavage and poly(adenosine diphosphate-ribose) polymerase (PARP) degradat
243 repair, are associated with response to poly(adenosine diphosphate-ribose) polymerase (PARP) inhibiti
244 a rational target for therapy based on poly(adenosine diphosphate-ribose) polymerase (PARP) inhibiti
245 ient epithelial ovarian cancer (EOC) to poly(adenosine diphosphate-ribose) polymerase (PARP) inhibito
248 the human bax promoter and found that poly (adenosine diphosphate-ribose) polymerase 1 recruited the
250 C-alpha, phospho-PKC-beta1, and cleaved poly(adenosine diphosphate-ribose) polymerase in post-CP/Rep
251 HR) as measured by hypersensitivity to poly (adenosine diphosphate-ribose) polymerase inhibition and
252 high tidal volume ventilation plus the poly-(adenosine diphosphate-ribose) polymerase inhibitor 3-ami
253 e II prospective clinical trial of the poly-(adenosine diphosphate-ribose) polymerase inhibitor olapa
254 nstability in response to radiation and poly(adenosine diphosphate-ribose) polymerase inhibitors, com
255 cyclin-dependent kinase inhibitors and poly(adenosine diphosphate-ribose) polymerase inhibitors.
256 ospho-PKC-alpha, phospho-PKC-beta1, and poly(adenosine diphosphate-ribose) polymerase were quantified
257 actor, caspase 3, caspase 8, caspase 9, poly(adenosine diphosphate-ribose) polymerase, B-cell lymphom
260 r 1) prevents it from inhibiting PARP1 [poly(adenosine diphosphate-ribose) polymerase], a critical DN
261 an essential substrate for sirtuins and poly(adenosine diphosphate-ribose) polymerases (PARPs), which
263 luorthanatrace (FTT) depicts activated poly (adenosine diphosphate-ribose)polymerase (PARP) expressio
265 ), enhanced cell death (caspase 3/7 and poly[adenosine diphosphate-ribose] polymerase activity, chrom
266 of PARPi-FL, a fluorescent inhibitor of poly[adenosine diphosphate-ribose]polymerase 1 (PARP1), which
267 by caspase-8, -9, and -3 and PARP (poly-ADP [adenosine diphosphate]-ribose polymerase) cleavage and d
268 A allele contributed to significantly lower adenosine diphosphate ribosyl transferase (ADPRT)/PARP-1
270 the synthesis and distribution of the unique adenosine diphosphate-ribosylating and vacuolating Commu
271 ng to multiple low-affinity sites comprising adenosine diphosphate ribosylation factor 1 (Arf-1)-guan
272 interacts with and regulates the activity of adenosine diphosphate ribosylation factor 6 (ARF6), a sm
275 idopsis thaliana AGD1 gene encodes a class 1 adenosine diphosphate ribosylation factor-gtpase-activat
276 the small guanosine triphosphatase (GTPase) adenosine diphosphate ribosylation factor-like protein 1
277 lyl cyclase (AC) in response to CT is due to adenosine diphosphate ribosylation of the small G protei
279 ation of p47phox, PLD-containing organelles, adenosine diphosphate-ribosylation factor 1, RhoA, prote
280 ads to activation of the Rac1 GTPase through adenosine diphosphate-ribosylation factor 6 (Arf6).
283 ship between oxygen consumption (baseline or adenosine diphosphate stimulated) and human leukocyte an
284 tains an RGD motif and binds equally well to adenosine diphosphate-stimulated human and rodent platel
289 tion, and they responded to stimulation with adenosine diphosphate, thrombin, and the PAR4 thrombin r
290 drolysis of adenosine triphosphate (ATP) and adenosine diphosphate to adenosine monophosphate on NK c
291 d upon the enzymatic transphosphorylation of adenosine diphosphate to adenosine triphosphate was used
295 iphosphate synthases, adenosine triphosphate/adenosine diphosphate translocase, and catalase (all p <
296 light transmittance aggregometry with 5 muM adenosine diphosphate, VerifyNow P2Y(12), and vasodilato
297 as the P2Y1-specific agonist 2-methylthio-5'-adenosine diphosphate was, again, only effective in a sm
299 phosphates (e.g., adenosine triphosphate and adenosine diphosphate) were readily degraded into a mono
300 switch I suggest a role for it in "ejecting" adenosine diphosphate when kinesin initially binds to th