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1 ction of PBCV-1, which is similar to that of adenovirus.
2 co-administered with the antigen-expressing adenovirus.
3 ition, we show inhibition of a non-enveloped adenovirus.
4 y increased when ILF3 is overexpressed using adenovirus.
5 virus, sapovirus, astrovirus, rotavirus, and adenovirus.
6 are increased when ILF3 is overexpressed by adenovirus.
7 s, some archaeal viruses, herpesviruses, and adenoviruses.
8 l assembly, especially for herpesviruses and adenoviruses.
9 cipients for several human herpesviruses and adenoviruses.
12 ic peptides identical or very similar to the adenovirus 12 E1A spacer region were determined and foun
13 g pathways activated during infection, while adenovirus 12 E4orf6 negates Chk1 activation by promotin
14 Ad155-RSV) using the viral vector chimpanzee-adenovirus-155, encoding RSV fusion (F), nucleocapsid, a
15 further randomly assigned at a 5:1 ratio to adenovirus 26 (Ad26)-vectored vaccine and placebo subgro
16 ne, Ad26.RSV.preF, a replication-incompetent adenovirus 26 vector encoding the F protein stabilized i
17 us 11 (Ad11pGFP) and adenovirus 5 containing adenovirus 35 fiber (Ad5F35GFP) viruses and T cells spec
20 Since the 1970s, replication-competent human adenoviruses 4 and 7 have been used as oral vaccines to
21 ; icddr,b AF 39.9%; 38.0, 41.8), followed by adenovirus 40/41 (Nationwide AF 17.9%, CI: 13.9, 21.9; i
25 even among vaccinated children, followed by adenovirus 40/41, Shigella/enteroinvasive Escherichia co
27 of virus tropism, but not hepatitis C virus, adenovirus 5 (ADV5), Zika virus, and influenza (H1N1) vi
29 HVTN 505 efficacy trial of a DNA/recombinant adenovirus 5 (rAd5) vaccine regimen, we found that host
30 ended and optimized our previous recombinant adenovirus 5 (rAd5)-based vaccine platform characterized
31 ation-competent adenovirus 11 (Ad11pGFP) and adenovirus 5 containing adenovirus 35 fiber (Ad5F35GFP)
32 achinery through transient expression of the adenovirus 5 E4orf6/7 protein, which recruits the cell-c
42 onchoalveolar lavage (BAL) following mucosal adenovirus (Ad)-SIV recombinant priming, intramuscular S
43 d following mucosal priming with replicating adenovirus (Ad)-SIV recombinants, systemic boosting with
44 t mice were then administered Cre-expressing adenovirus (Ad-Cre) to inactivate Tgfbr2 in transplanted
45 red through a replication incompetent type 5 adenovirus (Ad.mda-7) or with His-MDA-7/IL-24 protein, d
49 n haploid cells to identify host factors for adenovirus (AdV), a DNA virus that can cause severe resp
50 echanism supporting the persistence of human adenovirus (AdV), a virus that can kill immunosuppressed
51 a virus (PIV), human metapneumovirus (HMPV), adenovirus (AdV), rhinovirus (RV), bocavirus (BoV), and
53 related double-stranded DNA (dsDNA) viruses (adenovirus [ADV], BK virus [BKV], cytomegalovirus [CMV],
54 ur understanding of the relationship between adenovirus and DNA damage and cell cycle signaling pathw
56 4-Cre;Wnt10a(flox/flox) molars by Wnt4 shRNA adenovirus and kidney capsule grafts, the root furcation
57 tion with dual-antigen vectors, using simian adenovirus and modified vaccinia virus Ankara vectors.
58 , we modeled the inactivation of three-human adenovirus and two bacteriophages-MS2 and phiX174-in sur
59 s for immediate screening of novel oncolytic adenoviruses and selection of optimal viral genome alter
60 oorly permissive cancer cells with wild-type adenoviruses and the oncolytic chimeric adenovirus enade
61 anded DNA (dsDNA) phages, herpesviruses, and adenoviruses and, as such, is a viable antiviral therape
65 in the body.IMPORTANCE Replication-competent adenoviruses appear to be promising vectors for the deve
66 regimens, using either dendritic cells or an adenovirus approach targeting nuclear antigen EBNA1 foll
73 ovel in vivo proxy sensor of KOR activation, adenovirus associated double floxed inverted-HyPerRed, a
79 of MAV-1 to study replication-competent oral adenovirus-based vaccines but also highlight the fact th
82 turing and vaccination strategies.IMPORTANCE Adenovirus-based vectors are used today for gene transfe
84 vestigate delivery of both the BCG prime and adenovirus boost vaccination via the airway in a murine
85 articular, the heterologous EBNA1-expressing adenovirus, boosted by EBNA1-encoding MVA vaccination, d
86 adeno-associated virus serotype 9 (in vivo), adenovirus (both in vivo and in vitro), and small interf
87 reveal that complement component C4 inhibits adenovirus by inactivating the virus capsid through mech
89 show that systemic delivery of R-spondin via adenovirus can promote generation of differentiated tast
91 the loss of ZO-1, Connexin-45 and Coxsackie-adenovirus (CAR) proteins were reduced in atria of ZO-1c
94 PV3 was delivered by plasmid DNA, chimpanzee adenovirus (ChAdOx1) and modified vaccinia Ankara (MVA)
96 RAd technology that consists of an oncolytic adenovirus coated with MHC-I-restricted tumor-specific p
97 l during viral infection using a recombinant adenovirus coding for a mitochondrial tracer protein for
98 n, it has recently been shown that the major adenovirus condensing protein (polypeptide VII) is dispe
99 s (HUVECs) and SC cells were transduced with adenovirus containing eNOS promoter driving secreted alk
102 protected against subsequent infection with adenovirus, coronavirus, enterovirus/rhinovirus, and inf
104 t mice, expression of L-OPA1Delta by in vivo adenovirus delivery restored the morphology but not the
105 ated the mechanisms of LOAd713, an oncolytic adenovirus designed to block IL-6R signaling and to prov
107 of BALB/cByJ mice with tcMCMV or recombinant adenoviruses differentially activates T helper (T(h))1,
108 e from multiple HLA-A*01(+) donors prevented adenovirus dissemination, and nonstimulated T cells did
109 ulation of hepatic GRK2 during fasting using adenovirus-driven overexpression of this kinase in the l
111 with expression of other oncogenes, such as adenovirus E1A or MYC, HPV16 E7-expressing cells are sen
112 (forkhead box O3a)-BNIP3 (B-cell lymphoma 2/adenovirus E1B 19kDa interacting protein 3) pathway modu
114 ides equivalent to a region within the human adenovirus early region 1A protein that confers, in part
118 le hydrogel encapsulation for delivery of an adenovirus encoding Flagrp170 (Adv-Flagrp170), which has
119 irst report that delivery of rapamycin or an adenovirus encoding the dominant negative acting mTOR-mu
120 Here, we transduced replication-defective adenoviruses encoding human ACE2 via intranasal administ
121 Delta-24-RGD is a replication competent adenovirus engineered to replicate in tumor cells with a
122 rdiomyocytes transduced with RFFL-expressing adenovirus exhibited reduced total expression of the pot
123 cells may provide insight into how oncolytic adenoviruses exploit metabolic transformation to augment
126 ther virus with retrograde tropism, a canine adenovirus expressing Cre recombinase, was injected into
128 ne comprising a replication-deficient simian adenovirus expressing full-length SARS-CoV-2 spike prote
129 Intravenous administration of a recombinant adenovirus expressing wild-type human ABCC6 in Abcc6(-/-
130 to alter CaM function by directly injecting adenoviruses expressing CaM-wild type, a loss-of-functio
131 entricular cardiomyocytes were infected with adenoviruses expressing either wild-type CryAB (CryAB(WT
132 egalovirus (tcMCMV) or replication-deficient adenoviruses expressing individual murine cytomegaloviru
133 an DCs isolated from HIS mice immunized with adenoviruses expressing malaria/human immunodeficiency v
136 d safety of a new low-seroprevalence gorilla adenovirus (GAd; GC46) as a gene transfer vector in mice
137 receptor TRIM21 to block transduction by an adenovirus gene therapy vector but is partially restored
138 ults indicate that protein VII condenses the adenovirus genome by combining direct clustering and pro
143 ally intriguing and predicted emergent human adenovirus (HAdV) pathogen, which caused pneumonia and d
144 o characterize the etiological role of human adenovirus (HAdV) serotypes in pediatric gastroenteritis
145 om 10 of 14 patients were positive for human adenovirus (HAdV) while swabs from 2 of 14 patients were
147 has long been established that group A human adenoviruses (HAdV-A12, -A18, and -A31) can cause tumors
149 ta1-mediated nuclear import.IMPORTANCE Human adenoviruses (HAdVs) represent a ubiquitous and clinical
156 In addition, the most commonly used human adenovirus, human adenovirus subgroup C serotype 5 (HAd5
157 Cases were defined as hospital-acquired adenovirus identified from any clinical specimen (NICU p
161 etabolism induced by oncolytic and wild-type adenoviruses in cancer cells, which will be important to
162 strated good therapeutic index for oncolytic adenoviruses in patients with solid tumours when adminis
163 4.7% of cases and 1.5% of controls), enteric adenovirus (in 29.1% and 2.7%, respectively), Cryptospor
164 Co-expression of TRAM and an antigen from adenoviruses increased the transgene-specific CD8+ T cel
165 iruses such as vaccinia, herpes simplex, and adenovirus induced increased IFN production, which resul
166 angstrom(2)) and heterogeneous objects in an Adenovirus-infected cell over large fields of view (1.14
167 ed to viral replication centers early during adenovirus infection and is then targeted in an E1B-55K/
168 overlap between the metabolic phenotypes of adenovirus infection and transformed tumor cells may pro
170 characteristics of 5 children admitted with adenovirus infection during 2018-2019 who developed HLH
175 We identified the seasonality of rhinovirus, adenovirus, influenza A and B viruses, human parainfluen
178 transients in ventricular myocytes near the adenovirus-injection sites in Langendorff-perfused intac
182 viruses, eight human enteric viruses [human adenoviruses, JC and BK polyomaviruses, Aichi virus 1 (A
183 eral injection of Mgp.floxed mice with a Cre-adenovirus, led to an Mgp.TMcKO mouse which developed el
184 in 35 custom destination vectors, including adenovirus, lentivirus, PiggyBac transposon, and Sleepin
185 fied Jothikumar assay both consistently gave adenovirus levels lower than the commercial platform for
187 after inoculation with replication-deficient adenoviruses, lymphocytes from the submandibular gland e
188 in receptor knockout [L-IRKO] + GFP), before adenovirus-mediated add back of wild-type (WT) or mutant
189 cated by upregulating TIE2 signaling through adenovirus-mediated angiopoietin-1 (Angpt1) gene therapy
191 o insulin resistance in macrophages, whereas adenovirus-mediated expression of IL-10 ameliorates post
201 .IMPORTANCE To successfully replicate, human adenovirus needs to carry out a rapid yet ordered transc
204 9-based mouse model of SCLC by delivering an adenovirus (or an adeno-associated virus [AAV]) that exp
206 produced in mice what is observed with human adenovirus oral vaccines, it also highlighted that oral
207 , response, and successful containment of an adenovirus outbreak in a NICU associated with contaminat
209 evels in the brains of male db/db mice using adenovirus overexpressing Cav-1 (AAV-Cav-1) rescues lear
211 protected against subsequent infection with adenovirus (P = .044) and influenza virus (P = .081).
212 A (dsDNA) bacteriophages, herpesviruses, and adenoviruses package their genetic material into a precu
213 re, we study the morphology and mechanics of adenovirus particles with (Ad5-wt) and without (Ad5-VII-
217 ious studies employing replication-defective adenovirus (rAd) vectors that transiently express SIV in
219 lls, which identified the coxsackievirus and adenovirus receptor (CAR) as a candidate ReCV entry rece
220 ntified and validated the coxsackievirus and adenovirus receptor (CAR) as a functional proteinaceous
221 stigated the roles of the coxsackievirus and adenovirus receptor (CAR), CD46, and alphav integrins in
223 strongly express cell-surface coxsackie and adenovirus receptor (CXADR) genes, which can facilitate
225 we hypothesized that the coxsackievirus and adenovirus receptor (CXADR/CAR), although absent in norm
226 concentrations of soluble coxsackievirus and adenovirus receptor (sCAR) were similar with and without
227 n engineered sCAR-Fc (soluble coxsackievirus-adenovirus receptor fused to the carboxyl-terminus of hu
231 were immunized with replicating single-cycle adenovirus (SC-Ad) vaccines expressing clade B HIV-1 gp1
232 and protective efficacy of a single dose of adenovirus serotype 26 (Ad26) vector-based vaccines expr
236 cy trial testing DNA followed by recombinant adenovirus serotype 5 (rAd5) in circumcised, Ad5-seroneg
237 under increased scrutiny, since trials with adenovirus serotype 5-vectored (Ad5-vectored) HIV vaccin
238 The extent of alpha-helix in E1A from other adenovirus species can be correlated to a limited degree
239 As vaccines, vectors derived from human adenovirus species D serotypes 26 and 48 (HAdV-D26/48) a
240 post-transplant care, and early transfer of adenovirus-specific donor T cells during aplasia resulte
242 l transplantation, with adoptive transfer of adenovirus-specific T cells being an effective therapeut
243 e most commonly used human adenovirus, human adenovirus subgroup C serotype 5 (HAd5), when systemical
244 , PBCV-1 appears to represent an appropriate adenovirus surrogate for UV system performance evaluatio
245 cium bursaria chlorella virus (PBCV-1) as an adenovirus surrogate for validation of UV reactors was e
247 Syn3) is a replication-deficient recombinant adenovirus that delivers human interferon alfa-2b cDNA i
248 e identity with two recently isolated simian adenoviruses that contain cross-species genome recombina
250 ude cytomegalovirus, Epstein-Barr virus, and adenovirus, though recent published studies have success
252 fectious cycling in the presence of a helper adenovirus to yield a new AAV variant that then serves a
256 sequencing, here we profile m(6)A within the adenovirus transcriptome using a combination of meRIP-se
257 sion, and re-expressing the ET(B)R gene with adenovirus transduction, and determine the treatment eff
258 g RNA and small hairpin RNA interference and adenovirus transfection were adopted to manipulate the e
264 tumor cell-selective killing activity of the adenovirus type 2 early region 4 ORF4 (E4orf4) protein i
266 xamined.METHODSThe novel 2-dose heterologous Adenovirus type 26.ZEBOV (Ad26.ZEBOV) and modified vacci
267 me-boost regimen with recombinant chimpanzee adenovirus type 3 vectored Ebola Zaire vaccine (ChAd3-EB
268 with the Ebola vaccine candidate chimpanzee adenovirus type 3-vectored Ebola Zaire vaccine (ChAd3-EB
269 ZIKV vaccine using a low-seroprevalent human Adenovirus type 4 (Ad4-prM-E) and compared it to an Ad5
271 ara (MVA), vesicular stomatitis virus (VSV), adenovirus type 5 (Ad5), rhesus monkey rhadinovirus (RRV
272 us purification material selective for human adenovirus type 5 (AdV5) offered highly purified virus f
274 d twice mucosally with replication-competent adenovirus type 5 host range mutant (Ad5hr)-simian immun
275 were mucosally primed twice with replicating adenovirus type 5 host range mutant (Ad5hr)-SIV recombin
276 rols and the microbicide-only group received adenovirus type 5 host range mutant empty vector and alu
277 were primed twice mucosally with replicating adenovirus type 5 host range mutant SIV env/rev, gag, an
278 nding site in hexon; and noninfectious human adenovirus type 5 particles assembled in the absence of
279 study, we designed a replication-incompetent adenovirus type 5 to deliver a LANA-specific Cas9 system
280 A respiratory outbreak associated with human adenovirus type 7 (HAdV-7) occurred among unvaccinated o
283 The studies detailed here indicate that adenovirus utilizes ATR kinase and CDKs during infection
285 Single-dose vaccination with a recombinant adenovirus vector expressing hepacivirus non-structural
287 ecific immune profiles elicited by different Adenovirus vector types and emphasize the importance of
291 n five trial sites in the UK of a chimpanzee adenovirus-vectored vaccine (ChAdOx1 nCoV-19) expressing
292 ated the protective activity of a chimpanzee adenovirus-vectored vaccine encoding a prefusion stabili
293 l therapeutic delivery of a novel chimpanzee adenovirus-vectored vaccine expressing Ag85A (AdCh68Ag85
294 ted the immunogenicity of a novel chimpanzee adenovirus-vectored vaccine, ChAdOx1 nCoV-19 (AZD1222),
295 Vaccines based on replication-deficient adenovirus vectors either alone or in combination with a
300 dies, co-administration of a TRAM expressing adenovirus with a vaccine expressing the ME-TRAP malaria