ライフサイエンスコーパス: adept

1 In this study, we present ADEPT, a dynamic error detection method, based on the qu

2 In this paper, we present ADEPT, a new sequence alignment strategy for GPU archite

3 ro antibody-directed enzyme prodrug therapy (ADEPT), abrogated the cytotoxicity of a combination of A

4 erefore, we have named these protein domains ADEPTs (Additional Domains for Eukaryotic Protein Target

5 ilar results were obtained in an independent ADEPT (Airway Disease Endotyping for Personalized Therap

6 gs demonstrate the utility of MOSAIC and the ADEPT algorithm, and offer a new tool that can improve t

7 t comprising approximately two thirds of the ADEPTS and UKCTOCS samples and contrasted specific diagn

8 dely used in suicide gene therapy (GDEPT and ADEPT) applications as a activating enzyme for nitroarom

9 tor proposed for use in conjunction with the ADEPT approach.

10 y, the N-terminal third of BLAP75 is just as adept as the full-length protein in the promotion of dHJ

11 In nature, desaturases and acetylenases are adept at achieving this essential oxidative functionaliz

12 interface approach we employ is particularly adept at addressing problems with intricate interface ge

13 This virus is adept at altering its surface proteins, the proteins tha

14 But while a tool such as ChatGPT is adept at answering questions about manually input record

15 disease may be, in part, because MERS-CoV is adept at antagonizing early innate immune pathways-inter

16 Children who are adept at any one of the three academic 'R's (reading, wr

17 Analysts must become adept at application of appropriate statistical methods

18 vitro [8], we show that Abl and Arg are more adept at binding and phosphorylating cortactin.

19 Many species that are adept at biofilm formation have the capacity to produce

20 ings (Chrysopidae), where immatures are also adept at camouflage [1-4].

21 Oral treponemes are uniquely adept at capitalizing on the environmental conditions th

22 Modern breeding methods are very adept at combining this genetic variation in ways that a

23 VolcanoSV is adept at constructing comprehensive genetic maps encompa

24 erize little brown bats as flexible foragers adept at consuming a broad array of locally available pr

25 As social beings, we are adept at coordinating our body movements and gaze with o

26 SOS polymerases are adept at copying a variety of lesions, but the relative

27 on gene editing tool, prime editing (PE), is adept at correcting point mutations precisely with high

28 -kb ssRNA genome of coronaviruses makes them adept at cross-species spread while enabling a robust un

29 This feature is particularly adept at defining Single-Stranded Transcribing Enhancers

30 Microorganisms are adept at degrading chemically resistant aromatic compoun

31 Our visual systems are remarkably adept at deriving the shape and material properties of s

32 Though quantum mechanics has proved adept at describing the microscopic world, quantum super

33 Auditory systems are adept at detecting and segregating competing sound sourc

34 Subject 1 was consistently more adept at determining object size (74% accuracy; chance:

35 l for pairing ARGs with their hosts but less adept at discerning quantitative differences in ARG type

36 Chemists are visual creatures who are adept at discerning reactivity and chemical behavior fro

37 ch may be a widespread strategy for microbes adept at dissipating reducing equivalents via anaerobic

38 Humans are adept at distinguishing between stimuli that are very si

39 eae, which causes gonorrhea, is particularly adept at driving HIV-1 expression, but the molecular det

40 will differ as tumors evolve to become more adept at each of these characteristics.

41 t DNA polymerases, but POLN was particularly adept at efficient and accurate translesion synthesis pa

42 However, current biomarkers are not adept at enabling identification of occult invasive dise

43 Brucella spp. are adept at establishing a chronic infection in mammals.

44 Cancer cells are adept at evading cell death, but the underlying mechanis

45 Coronaviruses are adept at evading host antiviral pathways induced by vira

46 s life-long latency in the human host and is adept at evading host innate and adaptive immune respons

47 cally adapted to human infection and appears adept at evading normal human antiviral responses, yet i

48 Viruses are adept at evolving or co-opting genomic elements that all

49 n of different bases reveal that AAG is most adept at excising the deaminated lesion hypoxanthine (k(

50 us and Cenozoic, leptosporangiate ferns were adept at exploiting newly created niches in angiosperm-d

51 The results reveal that monkeys are adept at exploiting perceptual cues to locate a food rew

52 Humans are adept at extracting affective information from vocalizat

53 Humans are very adept at extracting the "gist" of a scene in a fraction

54 nvolutional neural networks are particularly adept at extracting valuable information from CVI data.

55 The small intestine is void of aquaporins adept at facilitating vectorial water transport, and yet

56 hibit behavioral responses, and (c) are more adept at flexibly switching behavioral patterns.

57 possible for psychopathic individuals to be adept at focusing on a single stimulus feature or goal b

58 ortunistic human pathogen that is especially adept at forming surface-associated biofilms.

59 They are adept at generating responses that closely mimic human c

60 incapable of tRNA mismethionylation are less adept at growth in the presence of antibiotics and stres

61 re cobalt/nickel-dependent phosphohydrolases adept at hydrolyzing p-nitrophenylphosphate and PP(i).

62 h as computed tomography, although perfectly adept at identifying and quantifying advanced calcificat

63 lack of chemical specificity, they are less adept at identifying unique chemical activity on those s

64 We show that WORMHOLE is particularly adept at improving LDO prediction performance between di

65 of Y-family DNA polymerase that is naturally adept at incorporating ribonucleotides by virtue of a le

66 onsistent with our analysis, LCs were highly adept at inducing primary CTL responses.

67 We are remarkably adept at inferring the consequences of our actions, yet

68 CD8(+) CTLs are adept at killing virally infected cells and cancer cells

69 Humans are adept at learning and exploiting statistical regularitie

70 e that soft-bodied (coleoid) cephalopods are adept at learning and remembering features of their envi

71 Numerous studies have shown that people are adept at learning novel object dynamics, linking applied

72 Brains, on the other hand, are adept at learning stable sensory representations given n

73 Humans and other animals are adept at learning to perform cognitively demanding behav

74 results suggest that humans are particularly adept at learning to protect others from harm.

75 violates Occam's razor, insofar as (i) it is adept at ligating 3'-monophosphate and 5'-OH ends; (ii)

76 rporation products formed by DNA polymerases adept at making small frameshift mutations in vivo.

77 As radiologists, we are adept at managing rapid technological change, which make

78 Honey bees are adept at maneuvering complex environments and collective

79 g this machinery, they are also particularly adept at manipulating cellular translation control pathw

80 uce hippocampal states that are more or less adept at map formation.

81 ligand-gated cation channels, they are most adept at mediating slow neuromodulatory functions that a

82 lassic model system in biology and a species adept at microscale interaction, as a biological platfor

83 One class of polymer that is particularly adept at mimicking the globular structure of enzymes are

84 reliance on social support or becoming more adept at mobilising resources to meet social needs.

85 The LSMs prove adept at modelling the progress of evolution as a functi

86 f naturally derived cell membranes, CNPs are adept at operating within complex biological environment

87 dence that variola proteins are particularly adept at overcoming human immunity, and the decreased fu

88 Some tumors were more adept at overcoming the additional endothelial cell laye

89 Bacteria are extremely adept at overcoming the effects of antibiotics through a

90 Humans are remarkably adept at perceiving and understanding complex real-world

91 It is particularly adept at predicting cumulative risk and event counting p

92 eveal that while regression models were more adept at predicting non-disease-related variation, AI-ba

93 The models, adept at predicting weld spot diameter and condensate ri

94 Humans are highly adept at processing speech.

95 In contrast, living organisms are remarkably adept at producing molecules and molecular assemblies wi

96 with a functionally variable cohort of taxa, adept at proliferating rapidly within hosts, which gradu

97 Primates are remarkably adept at ranking each other within social hierarchies, a

98 The nervous system is particularly adept at rapidly adapting to change, and this in fact ma

99 countries, public health systems have become adept at rapidly identifying the etiology and impact of

100 ty-determining region (CDR)H3 that is highly adept at recognizing such conserved epitopes, but their

101 ine and 6-O-methylguanosine caps, but is not adept at removing a deoxyguanosine cap.

102 This expands BrCa subpopulations adept at resisting therapy and reinitiating tumor growth

103 sposition outcome in some superfamilies, are adept at restructuring chromosomes and may have been ins

104 Artificial neural networks are remarkably adept at sensory processing, sequence learning and reinf

105 , we demonstrate that hHR23a is surprisingly adept at sequestering the ubiquitin moieties of a polyub

106 gent deep learning-based features extractor, adept at simplifying the retrieval of analogous images f

107 study proposes a novel multi-risk framework adept at simultaneous risk prediction for multiple clini

108 is anticipated that as surgeons become more adept at such procedures, maximally invasive procedures

109 lasma gondii enjoys a wide host range and is adept at surviving in both naive and activated macrophag

110 Influenza viruses are remarkably adept at surviving in the human population over a long t

111 Humans are adept at switching between goal-directed behaviors quick

112 With magnesium, DinB2 is adept at synthesizing A:oxo-dG or C:oxo-dG pairs.

113 Subjects were adept at the task, showing precise and graded modulation

114 NK cells are especially adept at this activity, as they direct lytic granules to

115 Bacteria are particularly adept at this and rely heavily upon ubiquitin-targeted v

116 As a highly invasive vector that is adept at transmitting malarial pathogens (eg, Plasmodium

117 This pathogen is adept at transporting and metabolizing a wide variety of

118 ow-capability hospitals may have become more adept at treating less complicated sepsis.

119 tiation, and point to pathogens particularly adept at triggering apoptosis that might preferentially

120 Humans are adept at uncovering abstract associations in the world a

121 Humans are adept at understanding speech despite the fact that our

122 Humans are remarkably adept at understanding speech, even when it is contamina

123 Clinicians must become more adept at understanding the molecular genetics of corneal

124 binds D-loop structures and is particularly adept at unwinding these structures.

125 re on auditory feedback and thus may be less adept at updating their stored motor programs.

126 Humans are adept at using facial similarity to recognize likely kin

127 dge in other minds and by being particularly adept at using situational support to build explanations

128 Here we show that hPolkappa is very adept at using template-primer misalignment as a novel m

129 e finches, M. gallisepticum was particularly adept at using the intra-cellular environment, which may

130 of Y-family DNA polymerase that is naturally adept at utilizing rNTPs or dNTPs as substrates.

131 We have shown that the ADEPT based Smith-Waterman algorithm demonstrates a peak

132 99 beta-lactamase (P99betaL), a component of ADEPT cancer therapies, revealed that the population pos

133 The 5-Cog paradigm, a brief, culturally adept, cognitive detection tool paired with a clinical d

134 Data were validated in the ADEPT cohort.

135 ely, the synthesis of Pu-UiO-66 demonstrates adept control of Pu(IV) coordination under hydrolysis-pr

136 key occupies an intriguing niche, displaying adept control of their hand movements yet their absence

137 ADEPT demonstrates a performance that is either comparab

138 We report an adept design of anchoring atomically dispersed platinum

139 We show that ADEPT detects previously unreported conductance states t

140 l gyrus, which differed from those with more adept foot motor skill who activated both the precentral

141 e public-private health sector partnerships, adept fund mobilizer, and advocate of the 'let's get it

142 Being able to perform adept goal-directed actions requires predictive, feed-fo

143 ndicate that the preferred hand was the most adept hand.

144 Antibody-directed enzyme prodrug therapy (ADEPT) has the potential of greatly enhancing antitumor

145 The outcome is that ADEPT improves upon prior efforts in identifying true er

146 Because adenovirus is adept in binding to the respiratory epithelium, we teste

147 h, which combines an e-Nose and an e-Tongue, adept in generating combined aroma and taste profiles.

148 s in action selection: Participants are more adept in invoking an appropriate aiming strategy when pr

149 nformatics software pipelines by integrating ADEPT in MetaHipMer a high-performance denovo metagenome

150 We demonstrated the efficacy of ADEPT in supporting existing bionformatics software pipe

151 id-infrared free-electron lasers have proven adept in surgical applications.

152 the associated outcome correlations and were adept in using that information to dynamically adjust th

153 Although dendritic cells (DCs) are adept initiators of CD4(+) T cell responses, their funda

154 ADEPT is the only tool to date that dynamically assesses

155 olds promise not only for advancing socially adept machines but also for enriching psychological scie

156 ate both long-distance underwater travel and adept maneuvers across a range of coastal terrains.

157 Helminth parasites are adept manipulators of the immune system, using multiple

158 controls) respiration rate modulation and in adept meditators (n = 23) during MW and FA meditation.

159 ency of hCPA1-268G was tested in an in vitro ADEPT model.

160 protein-protein interactions (PPIs) requires adept molecular design and synthesis strategies as well

161 For would-be Hermetic adepts of the Renaissance and Baroque, the ancient art o

162 as antibody-directed enzyme prodrug therapy (ADEPT) or gene-directed enzyme prodrug therapy (GDEPT).

163 The current analysis includes a subset of ADEPT participants (aged 20-24 years) who completed a cr

164 ofessional development to provide culturally adept, patient-centered care.

165 tools for analyzing microbiota data require adept programming skills and in-depth statistical knowle

166 elopment of Emotions and Personality Traits (ADEPT) prospective cohort study, depressive disorders in

167 expertise, provides general and technically adept radiologists insight into the potential of LLMs in

168 ADEPT's driver enables it to scale across multiple GPUs

169 ined at baseline to determine the residents' ADEPT score (range, 1.0-32.5; higher scores indicate wor

170 as a continuous measure, the ability of the ADEPT score to identify nursing home residents with adva

171 At baseline, the residents' mean (SD) ADEPT score was 10.1 (3.1) points and 65 residents (10.7

172 The AUROC for the ADEPT score's prediction of 6-month mortality as a conti

173 Using a cutoff of 13.5 on the ADEPT score, which also had specificity of 0.89, the AUR

174 enges that require mechanisms for prompt and adept sensing of and responses to stress if the bacteria

175 Overall ADEPT shows 10x faster performance in a node-to-node com

176 lysis (GSVA) was used to probe U-BIOPRED and ADEPT sputum transcriptomics to determine enrichment sco

177 and type 2-low asthmatic groups, but in the ADEPT study population CCL26 expression was optimal.

178 se Endotyping for Personalized Therapeutics (ADEPT) study profiled patients with mild, moderate, and

179 s of neuro Endocrine and Pancreatic TumourS (ADEPTS) study (benign disease controls and PDACs) and th

180 previous GPU-based approaches (CUDASW++3.0, ADEPT, SW#DB).

181 gn disease controls and PDACs collected from ADEPTS, the diagnostic-specific signature achieved an AU

182 Whether early hominins were adept tree climbers is unclear.

183 ese data strongly support the feasibility of ADEPT using a mutated human enzyme with a single amino a

184 nce of HIVSGD-derived BKPyV oral tropism and adept viral replication in human salivary gland cells co

185 Two key algorithms are implemented: ADEPT, which uses a physical model of the nanopore syste

186 in antibody-directed enzyme prodrug therapy (ADEPT) with beta-galactosidase for enzyme-specific activ