ライフサイエンスコーパス: adiposity

1 ults, suggesting that leptin regulates early adiposity.

2 idemia, hypertension, menopausal status, and adiposity.

3 anthropometric practice to estimate central adiposity.

4 te gut microbiota impacting WAT function and adiposity.

5 linear mixed effect models to predict infant adiposity.

6 rectly correlated to leptin, body weight and adiposity.

7 atty acid synthesis, insulin resistance, and adiposity.

8 c capacity and energy expenditure, promoting adiposity.

9 ciation between cow-milk fat consumption and adiposity.

10 th the specific metabolome related to infant adiposity.

11 es that control lipid absorption and reduced adiposity.

12 ty and 2.07 (95% CI: 1.74, 2.46) for central adiposity.

13 ects are mediated via an effect on abdominal adiposity.

14 n principles, on adult physical activity and adiposity.

15 dverse consequences for offspring growth and adiposity.

16 abolomics may be useful in predicting infant adiposity.

17 at participate in body weight regulation and adiposity.

18 no consensus on how best to assess abdominal adiposity.

19 FA), one-day-exposure-PM(2.5) did not affect adiposity.

20 ncy in mice is entirely due to their reduced adiposity.

21 of changes in body weight, caloric intake or adiposity.

22 among children with a tendency for abdominal adiposity.

23 ture leading to lower body weights and lower adiposity.

24 contributions to infant, childhood and adult adiposity.

25 of metabolic syndrome mediated by abdominal adiposity.

26 th positively and negatively correlated with adiposity.

27 ator of food intake, glucose metabolism, and adiposity.

28 e to the reduction of social inequalities in adiposity.

29 ALP and GGT were unrelated to adiposity.

30 and exercise training both increased muscle adiposity.

31 MC or AgRP neurons increases body weight and adiposity.

32 differ in both skeletal mass and bone marrow adiposity.

33 different macronutrients and weight gain and adiposity.

34 beyond that attributable to their increased adiposity.

35 -fat-diet-driven increases in bodyweight and adiposity.

36 by reduced voluntary exercise and increased adiposity.

37 s and mildly increased their body weight and adiposity.

38 e-pubertal BMI and/or mediated through adult adiposity.

39 tween PFOA in pregnancy and some measures of adiposity.

40 sia, low infant birth weight, and later-life adiposity.

41 in the case of obesity, cause a reduction in adiposity.

42 ted with higher T2D/IGT risk, independent of adiposity.

43 of metabolic pathways associated with infant adiposity.

44 a determinant of the X chromosome effect on adiposity.

45 thritis in relation to different measures of adiposity.

46 POMC neurons causes no significant change in adiposity.

47 which cow-milk fat minimizes risk of excess adiposity.

48 at intake is associated with lower childhood adiposity.

49 ng with an altered disease burden related to adiposity.

50 t percentage (-2.6%; P < 0.001) and visceral adiposity (-0.2; P = 0.01) than unfit peers.

51 l age (LGA) offspring had higher measures of adiposity, ~0.1 mmol/l higher non-HDL cholesterol and tr

52 (-0.38 Matsuda index, p = 0.001), increased adiposity (1.26 kg/m(2) BMI and 3.58 cm waist circumfere

53 ral siblings, urban migrants had 18% greater adiposity, 12% (360 calories/day) more energy intake, an

54 gestational glycemia on offspring abdominal adiposity (AA) in infancy and early childhood.

55 ker but still evident in models adjusted for adiposity (AAM: RR = 0.97 per year, 95% CI 0.95-0.98, p

56 ratios (HRs) and 95% CIs per SD increase in adiposity accounting for competing risks and adjusting f

57 gnancy affects head circumference growth and adiposity acquisition from birth through infancy.

58 to identify genetic variants that influence adiposity-adjusted leptin concentrations.

59 to assess its associations with measures of adiposity, adjusting for sociodemographic, health, and d

60 of rs72613567:TA was amplified by increasing adiposity, alcohol consumption, and genetic risk of fatt

61 Most identified favorable adiposity alleles are associated with higher subcutaneou

62 and test the hypothesis that such favorable adiposity alleles are associated with higher subcutaneou

63 studies, individuals carrying more favorable adiposity alleles had higher body fat % and higher BMI b

64 diometabolic disease risk features of excess adiposity, although a distinct phenotype developed on a

65 between parental education and indicators of adiposity among adolescents.

66 products with markers of metabolic risk and adiposity among adults in the United Kingdom.

67 and physical activity behaviours to greater adiposity among urban migrants could inform policies for

68 ific diet and activity behaviours to greater adiposity among urban migrants in India.

69 y expenditure contributed equally to greater adiposity among urban migrants in India.

70 usual 24-h sodium excretion and measures of adiposity among US adults.

71 sociated with overweight/obesity and central adiposity among US adults.

72 For adiposity, an increase in fermented dairy products [yogu

73 and the preconception/gestational period on adiposity and adipose tissue inflammation in offspring u

74 fspring had glucose, insulin resistance, and adiposity and also displayed cold sensitivity following

75 Patient characteristics such as adiposity and biomechanics of the knee could also have r

76 Negative associations between adult adiposity and breast cancer risk were observed in adjust

77 ggesting that the relation between abdominal adiposity and circulating triglycerides may be causal.

78 g may underlie correlations between visceral adiposity and cognitive impairment in humans.

79 vival despite paradoxically having increased adiposity and decreased control of blood glucose levels.

80 ment, and behavior) and 2 metabolic drivers (adiposity and dysglycemia) with applications to 3 cardio

81 Obesity summarises the evidence for visceral adiposity and ectopic fat as emerging risk factors for t

82 rom 2 inbred strains of mice which differ in adiposity and glucose tolerance, C57BL/6J and WSB/EiJ.

83 Leptin positively correlates with adiposity and has glucose-lowering effects, thus it may

84 velopmental exposure to TBT led to increased adiposity and hepatic steatosis at 14 and 20 weeks of ag

85 vely associated with longitudinal markers of adiposity and higher total cholesterol in infancy.

86 PR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral m

87 ree fatty acids, FFA) associated with excess adiposity and implicated in toll-like receptor-mediated

88 eficial metabolic phenotypes such as reduced adiposity and improved glucose tolerance.

89 od, maternal MFGM-PL supplementation reduced adiposity and increased oxygen consumption, respiratory

90 besity during lactation programmes offspring adiposity and insulin resistance, overriding exposure to

91 on-HIV participants with features of central adiposity and insulin resistance.

92 ticipants that were rigorously stratified by adiposity and insulin sensitivity: metabolically healthy

93 rted gene-environment interactions involving adiposity and LEP, LEPR, MnSOD, PPARgamma, PPARgamma2, a

94 PFAA concentrations and repeated markers of adiposity and lipid metabolism in infancy.

95 rons, energy expenditure was not altered but adiposity and lipid metabolism were both increased, even

96 fe was positively associated with markers of adiposity and lipid metabolism, but not with blood press

97 ently influence cardiometabolic risk through adiposity and lipid pathways.

98 le-body Tmem127 knockout mice have decreased adiposity and maintain insulin sensitivity, low hepatic

99 rence, which demonstrates a crucial role for adiposity and may account for previous conflicting findi

100 e intake is associated with higher offspring adiposity and obesity risk at age 5 and 9 y, with strong

101 lkyl substances (PFAS) exposure may increase adiposity and obesity risk in children.

102 al plasma metabolites associated with infant adiposity and other birth outcomes and (ii) investigate

103 ntitative estimates of alcohol use, smoking, adiposity and physical activity were used to establish a

104 y outcomes, reducing excess fetal growth and adiposity and pregnancy-related hypertensive disorders.

105 wnstream targets, concomitant with increased adiposity and reduced physical activity relative to wild

106 associated with modest increases in central adiposity and risk of overweight/obesity, but there was

107 al serum PFAS concentrations with adolescent adiposity and risk of overweight/obesity.

108 eview and meta-analysis of cohort studies on adiposity and risk of rheumatoid arthritis.

109 alleles associated with opposite effects on adiposity and risk of type 2 diabetes.

110 pattern of energy intake is associated with adiposity and robust circadian rhythms.

111 ained by race-related differences in central adiposity and SCD (stearoyl-CoA desaturase)-1 enzyme act

112 its detailed studies of interactions between adiposity and sex steroids in serum and tissues, includi

113 contains key photosensory, circadian rhythm, adiposity and sex-related genes and displays a latitudin

114 Liberating energy stores corrects adiposity and sleep defects of kin-29 mutants.

115 ely in adipocytes show significantly reduced adiposity and striking metabolic improvements when consu

116 and skeletal myofiber size, muscle function, adiposity and systemic metabolism in vivo.

117 l PFOA and PFHxS concentrations with central adiposity and the risk of obesity in adolescents, while

118 the circadian pattern of energy intake with adiposity and with internal circadian rhythms.

119 ulin, HOMA-IR, triglycerides, liver fat, and adiposity and with lower HDL at follow-up.

120 consumption was associated with lower child adiposity, and 10 studies did not identify an associatio

121 d chronic intestinal inflammation, increased adiposity, and altered gut microbiota composition in bot

122 prenatal cadmium exposure with child growth, adiposity, and cardiometabolic traits in 515 mother-chil

123 and the following outcomes: newborn weight, adiposity, and cord blood glucose, insulin, lipids, and

124 guidelines/algorithms for early behavioral, adiposity, and dysglycemia targeting is emphasized, as w

125 en than men in accordance with their greater adiposity, and explains other gene-environment interacti

126 lerance and displayed increased body weight, adiposity, and food intake.

127 ads to increased body weight gain, increased adiposity, and glucose intolerance in male knockout mice

128 nucleus (ARC) mediates MCH-induced feeding, adiposity, and glucose intolerance.

129 7b (-/-) mice exhibited reduced body weight, adiposity, and hepatic steatosis compared with WT contro

130 after adjustment for demographic, lifestyle, adiposity, and other health factors.

131 rance (IGT), with and without adjustment for adiposity, and to estimate the potential contribution of

132 iquid form, increases risk of dental caries, adiposity, and type 2 diabetes.

133 ncreased food intake, body weight, fat mass, adiposity, and whole-body glucose intolerance (p < 0.05)

134 iation of adult weight change with abdominal adiposity; and we examined the prevalence of metabolic s

135 ntile-dependent expressivity, including gene-adiposity (APOA5, APOB, APOE, GCKR, IRS-1, LPL, MTHFR, P

136 Abdominal and general adiposity are independently associated with mortality, b

137 he association between physical activity and adiposity are not consistent, and most are cross-section

138 Female offspring displayed increased adiposity as compared with males, but TBT did not lead t

139 ffect markers of glycemia, inflammation, and adiposity as compared with nontropical vegetable oils.

140 suggesting no specific influence of maternal adiposity as such.

141 ate and propagate increases in body mass and adiposity, as well as disturbances of insulin sensitivit

142 minished somatic growth and enhanced central adiposity associated with accumulation and enlargement o

143 The visceral and hepatic adiposity associated with weight gain since participants

144 lesterol levels, fasting glucose levels, and adiposity at 12 to 24 months' follow-up.

145 We assessed adiposity at 12 years using anthropometry and dual-energ

146 mulated risk factors in the first 1000 d and adiposity at 6 y is moderated by eating behaviors.

147 es in dietary intake, physical activity, and adiposity between siblings was examined using multivaria

148 utes/day) were associated with difference in adiposity between siblings, but no clear association was

149 examined the change in physical activity and adiposity between the East Village and control groups, a

150 and its risk factors (i.e., type 2 diabetes, adiposity, blood pressure, lipids, and glycaemic traits)

151 ets induced similar significant decreases in adiposity, body composition, and blood pressure, and imp

152 investigated the associations between excess adiposity, body shape evolution across life, and risk of

153 haracterized alleles, associated with higher adiposity but a favorable metabolic profile.

154 mice receiving WSB/EiJ microbiota increased adiposity but decreased plasma glucose.

155 ed a control chow diet and greater perirenal adiposity by the end of lactation.

156 diposity (centimeters squared), subcutaneous adiposity (centimeters squared), and intramuscular adipo

157 btained near diagnosis, we measured visceral adiposity (centimeters squared), subcutaneous adiposity

158 We evaluated sex-specific associations of adiposity characteristics and periodontal variables such

159 ches suggest these mediators explain most of adiposity-CKD-associated risk.

160 cross the life course, but lower measures of adiposity, compared to women with offspring who were app

161 reased rheumatoid arthritis risk, suggesting adiposity could be targeted for primary prevention.

162 The effects of PTH on bone marrow adiposity could enhance its anabolic actions by providin

163 thway led to increased somatic growth and/or adiposity demonstrating that disruption of Semaphorin 3

164 gain on standard and high-fat diets, and an adiposity-dependent improvement in glucose homeostasis.

165 ent female mice have reduced weight gain and adiposity despite similar caloric intake.

166 ound the time of puberty in boys, but not to adiposity development.

167 of admitted patients with COVID-19 show that adiposity, diabetes, and hypertension are risk factors f

168 rban siblings, accounting for 4% and 6.5% of adiposity difference between siblings, respectively.

169 identify metabolites associated with infant adiposity during the first 6 mo postpartum using untarge

170 Four cardiometabolic drivers-abnormal adiposity, dysglycemia, dyslipidemia, and hypertension-a

171 Weight, adiposity, energy expenditure, and circadian profiles of

172 ther inflammation-related factors, including adiposity, exercise, and diet, lifetime ovulatory years

173 other inflammation-related factors including adiposity, exercise, and diet, lifetime ovulatory years

174 ity (centimeters squared), and intramuscular adiposity (fatty infiltration into muscle [Hounsfield Un

175 thers, growth hormone and insulin secretion, adiposity, feeding, and glucose metabolism.

176 s of this polyol are predictive for visceral adiposity gain and development of type 2 diabetes.

177 Although HFD promoted weight gain, adiposity, glucose intolerance, hypertriglyceridemia, he

178 se models are protected against diet-induced adiposity, hepatic steatosis, and hyperglycemia.

179 ially prevented the increase in body weight, adiposity, homeostasis model assessment index, and adipo

180 e, sex, systolic blood pressure, measures of adiposity, homeostasis model assessment-estimated insuli

181 risk and a negative association with overall adiposity; however data from Latin America are scarce.

182 promoted by chemical 'obesogens' that drive adiposity, hunger, inflammation and suppress metabolism.

183 b/ob mice worsens their glucose homeostasis, adiposity, hyperphagia, and POMC neuronal projections, a

184 6 (Adv36) has been associated with increased adiposity, improved insulin sensitivity, and a lower pre

185 obesity during lactation alone can programme adiposity in a sex specific manner.

186 rdiometabolic risk associated with increased adiposity in adults and provide a thorough review of the

187 e a mediator of socioeconomic differences in adiposity in both genders; underlying mechanisms were ho

188 (P-NT) reduces food intake, body weight, and adiposity in diet-induced obese mice when administered o

189 ed activation of energy metabolism increases adiposity in humans and other mammals.

190 alone reduced offspring weight but increased adiposity in male CO offspring before weaning.

191 er disease (steatosis), as well as increased adiposity in many species, leading to its characterizati

192 le to decrease systemic oxidative stress and adiposity in mice fed a high fat and fructose supplement

193 ched isocaloric diet reduced weight gain and adiposity in mice fed a high fat diet.

194 al factors appear to offset genetic risk for adiposity in mid to late adulthood, with some sex-specif

195 ediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet.

196 adipogenesis and protect against HFD-induced adiposity in offspring.

197 esity is likely to reflect a causal role for adiposity in the development of AD.

198 ch as childhood obesity and increased marrow adiposity in type 2 diabetes mellitus, as well as contri

199 role of adipocyte GIPR in the regulation of adiposity in vivo.

200 d glucose concentrations and greater gonadal adiposity (in females).

201 ance of fat distribution, as well as overall adiposity, in the pathogenesis of obesity-associated dis

202 al-weight patients, each SD greater visceral adiposity increased CVD risk by 70% (HR, 1.70 [95% CI, 1

203 tScore, percentage of body fat, and visceral adiposity increased linearly across the BMI categories a

204 improved body weight and other parameters of adiposity independently of calorie restriction.

205 A high visceral adiposity index was associated with adverse outcomes and

206 A high visceral adiposity index, either with or without dysglycemia, mig

207 ulticentric study suggests that higher child adiposity indicators are associated with short telomeres

208 th data treated as 2 cohorts) suggested that adiposity indices (abdominal [p = 0.02] and visceral [p

209 , and 10 metabolites that described maternal adiposity indices at 0.5 mo, 2 mo, and 6 mo postpartum,

210 assess the effect of longitudinal changes in adiposity indices through adolescence on arterial stiffn

211 Moreover, these animals resisted adiposity induced by ovariectomy and exhibited increased

212 ental DOSS exposure leads to increased adult adiposity, inflammation, metabolic disorder and dyslipid

213 Poorer liver function might not cause adiposity; instead higher ALT might reduce BMI, raising

214 The effects of excess adiposity, insulin resistance, and hepatic steatosis on

215 guring early primary drivers with subsequent adiposity, insulin resistance, beta-cell dysfunction, an

216 , but no changes in markers of inflammation, adiposity, insulin resistance, or predictors of diabetes

217 Race-by-adiposity interactions were significant in cross-section

218 Adiposity is an increasing public health problem in Chin

219 find that genetically determined increase in adiposity is associated with increased risk of AD (odds

220 Observationally, adiposity is associated with poorer liver function.

221 ion studies in adults suggest that abdominal adiposity is causally associated with increased risk of

222 the association between taste perception and adiposity is limited.

223 In women adiposity is more significant than in men overriding the

224 Increased adiposity is the strongest risk factor for developing di

225 , whether this association is independent of adiposity is unclear.

226 eople with obesity is associated with excess adiposity itself and is not simply a compensatory respon

227 We aimed to assess whether persistent high adiposity levels are associated with increased arterial

228 Associations of LTL with each adiposity marker were calculated using linear mixed mode

229 al pre-pregnancy body mass index (BMI) and 4 adiposity markers in children at age 8 (6-11) years were

230 Infant adiposity may be related to later metabolic health.

231 Abdominal adiposity may have a causal, unfavorable effect on plasm

232 Excess bone marrow adiposity may have a negative effect on bone growth and

233 Abdominal adiposity may trigger causal pathological processes, par

234 etween maternal SDB and offspring growth and adiposity measurements after controlling for gestational

235 rents and Children (ALSPAC) who had detailed adiposity measurements between the ages 9-17 years and a

236 )-transformed PFAS for each time period with adiposity measures and tested differences in these assoc

237 The associations of MVPA with 6-y changes in adiposity measures were also examined.

238 The link between adiposity, metabolic abnormalities, and arterial disease

239 th, faster walking, less obesity and central adiposity, more favorable biomarker profiles (C-reactive

240 With increasing US adiposity, nonalcoholic steatohepatitis (NASH) is now a

241 sessed the association of liver enzymes with adiposity observationally and using two-sample MR for va

242 Excess visceral and intramuscular adiposity occurred across all BMI categories.

243 Among ethnic groups, we compared adiposity of the trunk, intra-abdominal visceral cavity,

244 were independently associated with increased adiposity of urban siblings, accounting for 4% and 6.5%

245 y be explained by different ramifications of adiposity or body shape.

246 e even in the absence of increased offspring adiposity or markers of systemic insulin resistance.

247 with spawning migration timing but not with adiposity or sexual maturity, traits long perceived as c

248 rs of advanced lipoprotein characterization, adiposity, or insulin resistance were observed with secu

249 Adiposity outcomes were child BMI and sum of skinfolds (

250 Similar results were found for the other adiposity outcomes.

251 l, and shikimic acid predicted higher infant adiposity over the first 6 mo of life.

252 t associations between MUST and subcutaneous adiposity (P < 0.001), visceral obesity (P < 0.001), and

253 ndent of HDL cholesterol levels (P = 0.015), adiposity (P = 0.018), immunosuppressive medication (P =

254 etween maternal SDB and offspring growth and adiposity patterns during infancy.

255 evated ACR, while a metabolically "favorable adiposity" phenotype lowered ACR.

256 o evaluate the mechanistic pathways by which adiposity promotes AD.

257 Excessive adiposity raises blood pressure and accounts for 65-75%

258 Children reaching this adiposity rebound (AR) early are at risk for adult obesi

259 Energy balance affected maternal adiposity (recommended: -2.5+/-0.8 kg fat mass, excess:

260 ition, specific gut microbes may affect host adiposity regardless of dietary intake.

261 This study aimed to quantify maternal adiposity-related differences in the human milk metabolo

262 lood pressure, low-density lipoproteins, and adiposity-related outcomes, with little to no risk of se

263 sal effects on ACR, highlighting the role of adiposity-related traits in causing lower microvascular

264 esity(1-3), their functional consequences on adiposity remain elusive.

265 hological conditions that result from excess adiposity, such as hypertension, nonalcoholic fatty live

266 aits, including multiple traits representing adiposity, suggesting that perceived age may be a useful

267 In models without adjustment for adult adiposity, T2D/IGT risk was lower per year later AAM (re

268 h sexes displayed significantly lower BW and adiposity than controls.

269 imated 70% of cases are attributed to excess adiposity, there is an increased interest in understandi

270 y causal contribution of central and general adiposity to CKD risk and the underlying mechanism of me

271 rats weighed less but had comparable percent adiposity to WKY rats, which supports the use of HFD-fed

272 le was significantly associated with several adiposity traits with large effects (e.g. ~ 1.28 kg/m2 p

273 risk factors, including glycemic, lipid, and adiposity traits, on ACR.

274 tation and cardiometabolic health (including adiposity, type 2 diabetes mellitus, and cardiovascular

275 xercise endurance, associated with increased adiposity under basal conditions, and glucose intoleranc

276 l tools for assessing individuals for excess adiposity until new evidence emerges.

277 vier neonates with a propensity to increased adiposity versus insulin- or metformin-exposed groups.

278 y [body mass index (kg/m2) >=25] and central adiposity [waist circumference (WC): >88 cm for women, >

279 o early menarche unadjusted and adjusted for adiposity was 12.6% (95% CI 11.0-14.3) and 5.1% (95% CI

280 Among Chinese adults, adiposity was a major risk factor for NAFLD but not othe

281 Adiposity was assessed using BMI z-score (zBMI).

282 Maternal adiposity was associated with increased amounts of milk

283 ollected using validated questionnaires, and adiposity was estimated from thickness of skinfolds.

284 dinal analyses, using self-reported measure, adiposity was lower among those who were consistently ac

285 association between composite risk score and adiposity was moderated by eating behaviors.

286 Adiposity was similar among the "became inactive" and "c

287 Differences in body weight and adiposity were accompanied by higher REE and total energ

288 Visceral and intramuscular adiposity were associated with increased CVD incidence a

289 Measures of overall adiposity were more strongly associated with SIClamp in

290 ction of neutrophils and depletion of marrow adiposity were reduced in mice deficient for G-CSF; howe

291 General, and particularly abdominal, adiposity were strongly associated with mortality in thi

292 of short-chain fatty acids, and drove higher adiposity when transferred to germ-free mice.

293 mechanism of early life programming of adult adiposity, which is mediated by primary cilia in develop

294 , independently from glucose intolerance and adiposity, which was linked to chromosome 4.

295 eption exposure affects body composition and adiposity while gestation exposure affects metabolism an

296 eptin concentrations are strongly related to adiposity, whose heritability is quantile dependent.

297 red physical activity with accelerometry and adiposity with body-mass index and bioimpedance, and we

298 ed to study the causal relation of abdominal adiposity with cardiometabolic risk factors in children

299 nal associations between central and general adiposity with CKD are largely causal.

300 cle MPC activity led to strikingly decreased adiposity with complete muscle mass and strength retenti