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1  novel and effective approach to improve its adjuvanticity.
2 and size as critical factors affecting their adjuvanticity.
3 mma-Syk-Card9 pathway for APC activation and adjuvanticity.
4 ation is a critical determinant for Th1/Th17 adjuvanticity.
5  that stress is involved in the mechanism of adjuvanticity.
6 nd conversely that stress agents will elicit adjuvanticity.
7 plored the underlying basis for this form of adjuvanticity.
8 ice revealed a GM1-independent pathway of LT adjuvanticity.
9 y be a superior method for measuring mucosal adjuvanticity.
10 uirements for cytokine-mediated pathways for adjuvanticity.
11 ent mouse model, and oral immunogenicity and adjuvanticity.
12 LE-driven macrophage activation and Th1/Th17 adjuvanticity.
13 s I to the cell surface, showed superior HSV adjuvanticity.
14 ency, species-specific activity, and in vivo adjuvanticity.
15 N-gamma to antigen could further enhance its adjuvanticity, a chimeric protein involving IFN-gamma an
16 uvant interactions play an important role in adjuvanticity and antigen potency, but detailed mechanis
17 in intrinsic aspects of the process, such as adjuvanticity and antigenicity, or from microenvironment
18 that appears to be important for its mucosal adjuvanticity and immunogenicity.
19 ponses, including B-lymphocyte mitogenicity, adjuvanticity and macrophage activation.
20 eresting vaccine platform for their built-in adjuvanticity and simplicity of production process.
21 i-B7.2 Ab in vivo inhibited both the mucosal adjuvanticity and the immunogenicity of CT.
22 nicity, reduced allergenicity, and intrinsic adjuvanticity and thus represent promising vaccines for
23                      This study compared the adjuvanticity and toxicity of QS-18 and QS-21, assessing
24  actively engage immune effector mechanisms (adjuvanticity), and (3) the microenvironment of dying ce
25  greatly dampened both CT immunogenicity and adjuvanticity, and the differential CT responses in IgA(
26 toxic properties of CT can be separated from adjuvanticity, and the mCTs induce Ab responses via a Th
27 d their impact on F-CRM adsorption, INI-4001 adjuvanticity, and vaccine efficacy were explored.
28           Although there was a difference in adjuvanticity between AS03 and MF59 at a lower dose (3.7
29 n and, moreover, suggest novel mechanisms of adjuvanticity by non-toxic derivatives of type II entero
30 immunity and indicates that antigenicity and adjuvanticity can be decoded by distinct innate immune r
31  observations show that multi-pronged immune adjuvanticity can boost T cell responses to neoantigen-t
32 mark of stress, as well as inflammasomes and adjuvanticity, commensurate with those of alum, which ma
33                            We found that flu adjuvanticity correlates with the upregulation of proinf
34 erstanding of the mechanisms underlying alum adjuvanticity could help to improve AIT vaccine formulat
35 on of caspase 1, production of IL-1beta, and adjuvanticity, demonstrated by enhancing OVA-specific se
36 e inducible C-type lectin receptor), and its adjuvanticity depends on the integrity of its glycans.
37 lopment of host-directed therapy and optimal adjuvanticity for a number of infectious pathogens.
38 nses, indicating partial independence of TDB adjuvanticity from inflammasome activation.
39                              Discovery of CT adjuvanticity has prompted the generation of CT chimeras
40 endogenous danger signals has been linked to adjuvanticity; however, the role of extracellular ATP du
41 ANTES and CpG ODN had capacities for mucosal adjuvanticity, i.e., for enhancing serum and vaginal ant
42 fy DC-derived IL-2 as a key mediator of alum adjuvanticity in vivo and the Src-Syk pathway as a poten
43     To identify the determinants of Th1/Th17 adjuvanticity, in vivo tracking experiments using fluore
44 to examine the hypothesis that alum-mediated adjuvanticity is a function of stress and conversely tha
45               A pivotal role for pDCs in the adjuvanticity is ascertained by significant abrogation o
46                                    Thus, LPS adjuvanticity is based on MyD88 promoting T cell surviva
47 s, but whether these are responsible for the adjuvanticity is controversial.
48  is ill-known, and a better understanding of adjuvanticity is needed to develop improved adjuvants ba
49 immunization; therefore, unlike toxicity, LT adjuvanticity is not dependent on the AB5 holotoxin stru
50 most commonly used vaccine adjuvant, yet its adjuvanticity is often weak and mechanisms of triggering
51 ed whether neutrophil elastase regulates the adjuvanticity of alum, and whether a strategy targeting
52 ant, our results suggest a mechanism for the adjuvanticity of Alum.
53 the first time the structure, stability, and adjuvanticity of an antigen have been rationally designe
54  altering the ionizable lipid influences the adjuvanticity of an LNP; however, the impact of the poly
55 lls and antigen-presenting cells, the strong adjuvanticity of CFA could be attributed, at least in pa
56                    Although the mechanism of adjuvanticity of CT is not completely understood, it is
57 D11c (encoded by Itgax) was required for the adjuvanticity of CT.
58 relationship of these effects to the mucosal adjuvanticity of CT.
59 D as they increase both the antigenicity and adjuvanticity of dying cancer cells.
60  be approved for human use, we evaluated the adjuvanticity of Escherichia coli heat-labile toxin (LT)
61 gate the physicochemical characteristics and adjuvanticity of four-component LNPs.
62                               We studied the adjuvanticity of GPI-anchored CCL28 co-incorporated with
63                                          The adjuvanticity of IMDQ-PEG-CHOL was validated in a licens
64 se as an inhibitory DAMP to counterpoise the adjuvanticity of immunostimulatory DAMPs.
65 proteins prompted the investigation into the adjuvanticity of Invaplex.
66               In addition, we found that the adjuvanticity of LPS to induce T-cell activation is comp
67  that the toxicity, immunogenicity, and oral adjuvanticity of LT are dependent upon binding of the B
68 bunit to further understand the toxicity and adjuvanticity of LT.
69 eceptor through a mAb, we confirmed that the adjuvanticity of MF59 and Pam3CSK4 to a trivalent influe
70                                   The B cell adjuvanticity of MF59 appears to be mediated by the pote
71 nt-an adjuvant lipidoid-that can enhance the adjuvanticity of mRNA-LNP vaccines.
72      In this study, we further evaluated the adjuvanticity of rOv-ASP-1 and explored its mechanism of
73                                          The adjuvanticity of the CpG ODN was secondary to their dire
74 nthesis and establishment of the stand-alone adjuvanticity of the examined synthetic adjuvant (2b) op
75 urface pegylation on the biodistribution and adjuvanticity of the formulations, in a bid to further m
76 binding in the toxicity, immunogenicity, and adjuvanticity of the heat-labile enterotoxin of Escheric
77                These results demonstrate the adjuvanticity of the NP adjuvant in inducing persistent
78 relating the biodistribution pattern and the adjuvanticity of the strong CD8(+) T-cell inducing lipos
79              Recent discoveries suggest that adjuvanticity of tumor-derived heat shock proteins (HSPs
80 rmulation, thereby establishing the superior adjuvanticity of VCG over CpG.
81                           Interestingly, the adjuvanticity of VCG was concentration-dependent, since
82 r their potential involvement in MPL-induced adjuvanticity or in its ability to protect against sepsi
83 ty of cancer cells mostly by affecting their adjuvanticity rather than their antigenicity.
84 presentation, although the mechanisms of its adjuvanticity remain poorly understood.
85 ne use in humans, although the basis for its adjuvanticity remains poorly understood.
86 ne use in humans, although the basis for its adjuvanticity remains poorly understood.
87                                          PEI adjuvanticity required release of host double-stranded D
88                                  However, CT adjuvanticity required type-I IFN sensitivity, participa
89           In this article, we show that alum adjuvanticity requires IL-2 specifically released by DCs
90 ts without systemic exposure can afford good adjuvanticity, suggesting peripheral innate activation (
91 R3-dependent mechanism of action, and robust adjuvanticity, the PVP-057 pharmacophore has prophylacti
92 ility and genomic instability, (2) enhancing adjuvanticity through the activation of cytosolic immuni
93      To identify innate immune correlates of adjuvanticity to influenza subunit vaccine, we investiga
94 een proposed that IFN type I is required for adjuvanticity to influenza vaccines, we found that MF59
95 , and the effect of stereochemistry on their adjuvanticity toward ovalbumin was investigated.
96                          Furthermore, PTX co-adjuvanticity was Bhlhe40 dependent.
97                                 When mucosal adjuvanticity was examined, both dmCTs induced enhanced
98              Even though significant mucosal adjuvanticity was seen with both mCT E112K and nCT, neur
99 gap junctions were blocked, PS-GAMP-mediated adjuvanticity was substantially abrogated in vivo.
100                                              Adjuvanticity was then validated in ferrets.
101 role of edema toxin (EdTx) components in its adjuvanticity, we examined how a PA mutant lacking the a
102 in molecules, which were developed to retain adjuvanticity without the toxicity associated with the n

 
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