ライフサイエンスコーパス: admix

1 s either in an AB5 structure or with A and B admixed.

2 Interestingly, this paramagnetic state admixes a zig-zag spin mode analogous to the zig-zag ord

3 on trans-ancestry meta-analysis results for admixed African (Nagelkerke's R(2) = 0.032; liability R(

4 In admixed African Americans and Hispanic/Latino Americans,

5 al and clinical cardiovascular disease among admixed African Americans compared with other population

6 c basis of variation in renal function among admixed African Americans.

7 y disease discovered by admixture mapping in admixed African Americans.

8 a population-based sample of 1,018 unrelated admixed African Americans.

9 n studies of 6152 cases and 3918 controls of admixed African ancestry, and of 1234 cases and 3090 con

10 We observed a decline in heterozygosity in admixed Africans and found that the Eurasian admixture c

11 e of near-clonal lineages that diverged from admixed Amazonian ancestors, accompanied by a significan

12 We incorporated Admixed American 1000 Genomes populations (1000 G, n = 3

13 address the implications of the creation of admixed American genomes, containing novel allelic combi

14 erences of parental and first generations of admixed ancestries.

15 Our sample includes 12 individuals who have admixed ancestry and who have varying degrees of recent

16 gtze River, each one connected to a group of admixed ancestry.

17 or European ancestry groups reflected their admixed ancestry.

18 g relatedness in structured populations with admixed ancestry.

19 y detected down to 0.01ng DNA and 1% meat in admixed and burger products.

20 nd 3-aminopropyltriethoxysilane (APTES) were admixed and covalently attached to a polystyrene based-m

21 The population is highly admixed and has a cohesive and conservative lifestyle.

22 the genomes of individuals of P. formosa are admixed and intermediate between Poecilia latipinna and

23 f local ancestry can improve eQTL mapping in admixed and multiethnic populations, respectively.

24 te the genetic correlation structure of both admixed and non-admixed individuals using simulated and

25 ferent population structures (admixed or non-admixed) and relatedness (related or independent).

26 suggestions that the Menorcan population is admixed, and indicate a role of non-breeding behaviours

27 hich induce immune responses directed at the admixed antigens.

28 nd gangliosides, and even in the presence of admixed B subunit, it displayed low cyclic AMP (cAMP) in

29 These populations are three-way admixed between European, African, and Native American a

30 m European stock, whereas others are clearly admixed between indigenous and European dogs.

31 rican Americans, Hispanics, East Asians, and admixed cases and controls were successfully genotyped.

32 r domestic) of the genomic blocks carried by admixed cats, also looking for possible deviations from

33 blocks were detected in the genomes of most admixed cats, which likely originated from hybridization

34 f asthma exacerbations was performed in 1347 admixed children treated with ICS (Hispanics/Latinos and

35 ants associated with asthma exacerbations in admixed children treated with ICS and to validate previo

36 -matter coupling, where excitons and photons admix coherently to form polaritons up to room temperatu

37 ticular emphasis on chromosome 11 in two SCA admixed cohorts obtained from urban populations of Brazi

38 e and promote research in multi-ancestry and admixed cohorts, we outline key methodological considera

39 i were differentially retained in the modern admixed Colombian population based on their utility in t

40 human health and fitness via analysis of an admixed Colombian population from Medellin.

41 er" subjects whose ethnicity is different or admixed compared to most other subjects in the genotyped

42 ring the exposure, the corrosion loss of the admixed concrete coupons was 30% lower than that of the

43 The sulfide uptake rate of the admixed concrete was also 30% lower, leading to a higher

44 he corrosion in sewers using calcium nitrite-admixed concrete.

45 The limit of detection, under gelatin admixed conditions, was 0.005 ng/uL.

46 genetic markers and speech recordings in the admixed creole-speaking population of Cape Verde, whose

47 In simulated admixed data, IBDrecomb obtains higher accuracy than adm

48 Admix'em is designed to simulate selection in admixed po

49 We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulation

50 Pharmacogenetic studies of admixed ethnic groups have been limited to small candida

51 Hispanics/Latinos and African Americans and admixed Europeans, Africans, and Asians.

52 Drawing from information on over 400 admixed genomes sourced from replicate transects across

53 of our approach is that it incorporates the admixed genomes themselves jointly with public datasets,

54 rmance over existing approaches in sequenced admixed genomes.

55 on owing to heterogeneity in ancestry within admixed groups [25, 26] and idiolectal variation owing t

56 tobacco-derived biomarkers in smokers from 3 admixed groups in the Multiethnic Cohort Study (1993-pre

57 raphic history of the species, properties of admixing groups, identification of signatures of natural

58 Brazilians were more admixed, had a lower African background (43% vs. 78% on

59 ile but also conferred increased motility to admixed HeLa cervical cancer cells.

60 102 (9.9%) persons of genetically determined admixed Hispanic ancestry had more impairment by GDS or

61 In multivariate models including persons of admixed Hispanic ancestry, those with haplogroup B had l

62 rican, European, and African segments of the admixed Hispanic/Latino genomes.

63 nd that patterns of linkage-disequilibria in admixed Hispanic/Latino populations are largely affected

64 multi-ethnic whole-genome sequencing data in admixed Hispanics/Latinos.

65 his visualization of the mosaic structure of admixed human chromosomes gives results similar to anoth

66 potential mitonuclear incompatibility in six admixed human populations from the Americas: African Ame

67 the widespread study of genetic variation in admixed human populations, such as African-Americans, th

68 ew estimators exist for individuals that are admixed, i.e. have ancestry from more than one populatio

69 to Korea approximately 1,800 years ago, and admixed in secondary contact zones.

70 y admixed population, when the phase of each admixed individual's genotype relative to the pair of lo

71 genetic ancestry at a genomic location of an admixed individual, is widely used as a genetic marker i

72 e ancestry of each chromosomal segment in an admixed individual.

73 ncestry estimation along the genome for each admixed individual.

74 stry at each locus in the genome of recently admixed individuals (e.g., Latino Americans) plays a maj

75 mpowering disease mapping studies in African-admixed individuals and will facilitate gene discovery f

76 ates of the genome-wide average ancestry for admixed individuals are consistent between exome sequenc

77 ancestry of specific chromosomal regions in admixed individuals are useful for studies of human evol

78 The inference of local ancestry of admixed individuals at every locus provides the basis fo

79 e wildcats and investigating the ancestry of admixed individuals becomes thus a conservation priority

80 in whole blood and colorectal tissue of 132 admixed individuals from Colombia, we identified sites w

81 s consensus local ancestry calls in the real admixed individuals from the 1000 Genomes Project.

82 bspecies labels, we identify 90 suitable non-admixed individuals in the European Association of Zoos

83 We provide a local ancestry map for admixed individuals in the GTEx v8 release and describe

84 Placement of admixed individuals on the landscape is more complicated

85 ves better localization for both unmixed and admixed individuals than existing methods despite using

86 this overestimation is larger for samples of admixed individuals than for samples of unadmixed indivi

87 xplore the use of local ancestry in recently admixed individuals to find signals of gene-gene interac

88 ry inherited from parental populations among admixed individuals to map associations for diseases, th

89 orrelation structure of both admixed and non-admixed individuals using simulated and real data.

90 two genetic clusters, within which the least admixed individuals were found in Europe/central Asia an

91 Inferring the ancestry of each region of admixed individuals' genomes is useful in studies rangin

92 sweet orange, is the offspring of previously admixed individuals, but sour orange is an F1 hybrid of

93 In sequence association studies of admixed individuals, cryptic relatedness and population

94 Among admixed individuals, deleterious haplotypes and their an

95 genetic architecture of complex diseases for admixed individuals, highlighting the need for further s

96 ver genes influencing skin colour in African-admixed individuals.

97 re available for inferring local ancestry in admixed individuals.

98 irwise relatedness from genetic data between admixed individuals.

99 software has a capacity for analyzing 6-way admixed individuals.

100 y or used for genetic association studies in admixed individuals.

101 terns of ancestry segments in chromosomes of admixed individuals.

102 s classifier to infer the local ancestry for admixed individuals.

103 observation of ancestry switch points among admixed individuals.

104 spersed within the chromosomes of ethnically admixed individuals.

105 ly migrants to Africa, and non-native, breed-admixed individuals.

106 across ancestrally distinct segments within admixed individuals.

107 s polygenic components of gene expression in admixed individuals.

108 rtion from multiple ancestral populations in admixed individuals.

109 estry compared to random expectations in the admixed individuals.

110 nstrate its functionality with the data from admixed individuals.

111 ng populations, except between the large and admixed interior populations.

112 (26)Al radionuclide is thought to have been admixed into the initially (26)Al-poor protosolar molecu

113 to differentiate between forest, savanna and admixed isolates, which has not previously been possible

114 pean populations and there are no reports in admixed Latin American individuals.

115 lysis of whole genome sequences sampled from admixed Latin American populations in Colombia, Mexico,

116 t wave, and that some of the resulting newly admixed lineages were then reintroduced to Central Ameri

117 ., the evolutionary window separating widely admixing lineages versus nascent reproductively isolated

118 Overall, the admixed map is well predicted by the average proportion

119 by an ancient family with Egyptian-Lebanese admixed members.

120 recapitulated in the indigenous ancestry of admixed mestizo individuals across the country.

121 ic variants conferring NMO susceptibility in admixed Mexican patients.

122 In this study, we use an admixed multi-parental population of Drosophila melanoga

123 ghur samples could be challenging due to the admixed nature of the population.

124 uish cancer clones from one another, or from admixed non-neoplastic cells.

125 Population heterogeneity through admixing of different founder populations can produce sp

126 source types and diversifying microhabitats (admixing of oaks and conifers) were important and mostly

127 emperature fluids (<200 degrees C) formed by admixing of seawater, however, are invariably enriched i

128 Admixing of stellar-derived (26)Al to the protoplanetary

129 length among individuals, as well as by the admixing of telomeres inherited from affected parents wi

130 neuropathological lesions in 1,092 Brazilian admixed older adults, their correlation with cognitive a

131 ests across different population structures (admixed or non-admixed) and relatedness (related or inde

132 ations, we infer that Spanish teosinte is of admixed origin, most likely involving Zea mays ssp. mexi

133 alganoi/jeanneae and P. punctatus/hespericus admix over hundreds of kilometers, suggesting that they

134 An admixed population and its ancestral populations bear di

135 ence; and (7) when samples are drawn from an admixed population and one of its parent populations, th

136 enetic diversity, a sign of an older or more admixed population but not of a long-term isolate.

137 However, this admixed population challenges traditional management reg

138 ect selection on the marker locus within the admixed population due to covariance with the trait valu

139 Our method is applicable to an admixed population from an arbitrary number of ancestral

140 ypes give rise to both the ancestral and the admixed population haplotypes, we employ an infinite hid

141 ribes both the ancestral populations and the admixed population jointly in a unified framework.

142 ancestral origin along the chromosome of an admixed population requires the use of ancestry informat

143 estimating admixed proportions in three-way admixed population scenarios.

144 -by-distance) and the anthroponotic subtype (admixed population structure).

145 roach efficiently captures both discrete and admixed population structures.

146 Color variation in an admixed population suggests that this light Sand Hills p

147 detect selection using individuals from the admixed population than from the nonadmixed population,

148 selection using individuals sampled from the admixed population than from the nonadmixed population.

149 parameters when using samples drawn from the admixed population under certain conditions.

150 ntly contributes to NMO susceptibility in an admixed population, and is consistent with differences i

151 somatic alterations in OpSCC samples from an admixed population, and to test for association with cli

152 a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry

153 en genotypes and local ancestries on a 3-way admixed population, when the phase of each admixed indiv

154 nd Asia rather than settlement by an already admixed population.

155 vious cardiovascular event) and 1 study with admixed population.

156 d's feral chickens are a highly variable and admixed population.

157 lation structure in a simulated case-control admixed population.

158 etween mean fitness of immigrants and in the admixed population.

159 local genetic ancestry of individuals in an admixed population.

160 lation and further extend it to generate the admixed population.

161 and time-consuming ancestry inference in an admixed population.

162 res from genotype-based methods in three-way admixed population.

163 nteraction can influence disease risk in the admixed population.

164 stry analysis of genotype data from recently admixed populations (e.g. Latinos, African Americans) pr

165 he feature selection approaches in three-way admixed populations (including Latino populations).

166 ze the genetic basis of skin pigmentation in admixed populations (N = 2,104).

167 vely associated with asthma exacerbations in admixed populations (P <= 5 x 10(-6) ).

168 ure, but the performance of these methods in admixed populations (such as African Americans) has not

169 satellite markers in 249 individuals from 13 admixed populations across Latin America.

170 led type I error rates, even when applied to admixed populations and populations with substructure.

171 However, the distribution of ROH in admixed populations and their relationship to deleteriou

172 vidence of mitonuclear interactions in human admixed populations and we discuss their implications fo

173 Association studies in recently admixed populations are extremely useful to identify the

174 Genetic association studies in admixed populations are underrepresented in the genomics

175 Admixed populations arise when two or more previously is

176 We generated replicate admixed populations between two pairs of sister species

177 dmix'em is designed to simulate selection in admixed populations but can also be used as a general po

178 estimate h(2) from unrelated individuals in admixed populations by first estimating the heritability

179 itize informative markers for multi-ancestry admixed populations by utilizing feature selection metho

180 nd found that genome-wide statistics vary in admixed populations even once ancestry proportions have

181 he Human Genome Diversity Panel and recently admixed populations from the 1000 Genomes Project.

182 Admixed populations have been used for inferring migrati

183 periods of gene flow shaped the diversity of admixed populations in the Americas-70% of the European

184 ariation remains to be discovered in African-admixed populations in the Americas.

185 determine the ancestry proportion in two-way admixed populations including African Americans, there a

186 Admixture mapping based on recently admixed populations is a powerful method to detect disea

187 The extent of recent selection in admixed populations is currently an unresolved question.

188 oach to addressing the genetic complexity in admixed populations is to infer ancestry.

189 Admixed populations offer a unique opportunity for mappi

190 Association studies among admixed populations pose many challenges including confo

191 erred map with high-resolution maps from non-admixed populations provides evidence of fine-scale diff

192 alysis of skin pigmentation GWAS in recently admixed populations provides new insights about the gene

193 Genetic analysis of admixed populations raises special concerns with regard

194 apping and trait heritability estimation, in admixed populations remains critically underexplored.

195 ssociation studies, particularly in recently admixed populations such as African Americans.

196 Genetically admixed populations that speak creole languages show hig

197 AAs and HLs are admixed populations that trace their genetic ancestry to

198 roach that exploits the genomic structure of admixed populations to date and characterize historical

199 support the advantages of analyzing African-admixed populations to discover new genes influencing sk

200 stry (LEA) using Local Ancestry inference in adMixed Populations using Linkage Disequilibrium method

201 te the performance of tests of neutrality in admixed populations using plausible demographic models f

202 The admixed populations were maintained by random mating in

203 asthma-associated locus that is relevant to admixed populations with African ancestry and highlight

204 try and admixture mapping test statistics in admixed populations with contributions from any number o

205 llows for rapid and realistic simulations of admixed populations with selection.

206 hods perform very well for both discrete and admixed populations with subject outliers.

207 d a novel approach (aMAP, ancestry of Modern Admixed Populations) for inferring local phased ancestry

208 se a method, REAP (relatedness estimation in admixed populations), for robust estimation of identity

209 TL4-ARHGAP28 genomic region was confirmed in admixed populations, although a different variant was id

210 association studies, association studies in admixed populations, and homozygosity mapping studies.

211 mbination rates, inferring local ancestry in admixed populations, and importance sampling of coalesce

212 This approach, especially in admixed populations, has the potential to produce mislea

213 is not significant in other heterogeneous or admixed populations, or in fetal genotype analysis.Popul

214 erbations despite treatment, particularly in admixed populations, such as Puerto Ricans and African A

215 ignals and local hunter-gatherer ancestry in admixed populations, suggesting that selection has maint

216 es tailored for analysis of multi-ethnic and admixed populations, we describe a framework for analysi

217 to provide a diverse genome map of different admixed populations, which can be used for future pharma

218 GWAS were followed up for replication in the admixed populations.

219 could contribute to phenotypic variation in admixed populations.

220 ating a need to improve our understanding of admixed populations.

221 netic architecture of quantitative traits in admixed populations.

222 ontribute to complex diseases in genetically admixed populations.

223 orical structure in the ancestry of American admixed populations.

224 ls where different types of mtDNA coexist in admixed populations.

225 ilable) and women of heterogeneous origin or admixed populations.

226 he difficulty in replicating associations in admixed populations.

227 d identifying tracts of distinct ancestry in admixed populations.

228 ng probabilities and kinship coefficients in admixed populations.

229 likely exists, e.g., samples collected from admixed populations.

230 or performing genetic association studies in admixed populations.

231 nformative markers for assessing ancestry in admixed populations.

232 l ancestry in genetic association studies of admixed populations.

233 ure population genetic studies of additional admixed populations.

234 on is compulsory for association analyses in admixed populations.

235 ower for rare variant association mapping in admixed populations.

236 tical difference: (i) association studies in admixed populations; (ii) association studies in presenc

237 n that sex is costly and typically serves to admix preexisting genetic diversity from genetically div

238 h with genotype-based approach in estimating admixed proportions in three-way admixed population scen

239 aques, the effects of a 500-fold range of an admixed recombinant modified vaccinia Ankara (MVA) expre

240 Admixed recruited skin macrophages enhanced transplanted

241 the influence of sleep patterns in a highly admixed rural population with a conservative lifestyle.

242 We present a GWAS of skin pigmentation in an admixed sample from Cuba (N = 762).

243 eta-analysis including the Cuban sample, and admixed samples from Cape Verde, Puerto Rico and African

244 e perform genome-wide cis-eQTL mapping using admixed samples in seven tissues, adjusted by either glo

245 RFMix is capable of learning from the admixed samples themselves to boost performance and auto

246 faster than IBIS, the fastest are biased in admixed samples, with KING inferring 30.8% fewer fifth d

247 proposed method by simulation under various admixing scenarios and present empirical analysis result

248 tatives of the Tupi coastal branch, a small, admixed, self-reported Tupiniquim community, as well as

249 to reduce ambiguity in the deconvolution of admixed sequencing data into multiple haplotype-specific

250 dian sources over U.S.-derived lead, with an admixed signature typical of Chinese anthropogenic lead

251 ci in the 1982 Pelotas Birth Cohort Study of admixed Southern Brazilians, the COGENT-BP study of Afri

252 her 46 individuals have been identified with admixed subspecies ancestries, which therefore over time

253 atory cell phenotype responses in allogeneic admixed T cells (>4.8 fold; P < 0.05).

254 -ethylene dimethacrylate) monolith by simply admixing them in the polymerization mixture followed by

255 eakers migrated to and through the mainland, admixing there before continuing to western Indonesia.

256 D-mannitol was admixed to MAC at 5, 10 and 20 wt% D-mannitol per total

257 In addition, we developed a robust admixed tumor model consisting of CD30(+) and CD30(-) ca

258 but the genetic determinants of CRP in these admixed United States minority populations are largely u

259 ous study designs, including homogeneous and admixed unrelated-subject and family as well as mixtures

260 find that these enigmatic canids are highly admixed varieties derived from gray wolves and coyotes,

261 evealed that extant mainland populations (i) admixed widely irrespective of ancestry, although admixt

262 the EDC-activated anti-HFA antibody (Ab) was admixed with 1% (v/v) 3-aminopropyltriethoxysilane (APTE

263 ze of four) to receive rindopepimut (500 mug admixed with 150 mug GM-CSF) or control (100 mug keyhole

264 cipients that received 500 allogeneic islets admixed with 5 x 10(5) - 7 x 10(5) Tregssurvived 83.6 +/

265 CRD mice received a diet admixed with 6.6 or 60 mg/kg of the potent and selective

266 t approximately the same time and might have admixed with a population related to the Paleo-Eskimos.

267 at ambient temperature to give the borole 9 admixed with a small amount of its thermal follow-up pro

268 ice immunized with the epitope-based vaccine admixed with a synthetic oligodeoxynucleotide adjuvant o

269 le out-of-Africa dispersal, and subsequently admixed with archaic populations.

270 is low-penetrance line, 3% of the genome was admixed with BALB alleles, suggesting a remote contamina

271 shed from primary and metastatic cancers are admixed with blood components and are thus rare, making

272 unt for partial voxel components--myocardium admixed with blood in a single voxel.

273 Nasal application of Protollin or Protollin admixed with BPEx was sufficient to inhibit allergic low

274 ry administrations of Protollin or Protollin admixed with BPEx, followed by consecutive daily BPEx ch

275 Graft experiments showed that CSCs admixed with CAFs produced prostatic glandular structure

276 lls under H2O2-induced oxidative stress when admixed with CAR-CAT T cells.

277 halosporolide E (which is typically obtained admixed with cephalosporolide F) was accomplished.

278 We demonstrate that immunization with dmLT admixed with CfaEB induces robust serum and fecal antibo

279 when higher doses of dmLT (1 to 5 mug) were admixed with CfaEB or, even better, when a CfaE-LTB chim

280 After their introduction to Europe, potatoes admixed with Chilean genotypes.

281 Vaccination with dscCfaE, or dscCfaE admixed with CTB or LTB, resulted in a reduction of atta

282 circulates in the plasma of cancer patients admixed with DNA from noncancerous cells.

283 e show that most modern wild rice is heavily admixed with domesticated rice through both pollen- and

284 aE-heat-labile toxin B subunit (LTB) chimera admixed with double mutant heat-labile toxin (LT) LT-R19

285 used to show that purified beta4+ adult AECs admixed with E14.5 lung single-cell suspensions and impl

286 ostimulatory (CpG) oligodeoxyribonucleotides admixed with either Alhydrogel or ISCOMATRIX adjuvant.

287 In some cases, stromal hyperplasia was admixed with epithelial metaplasia, sometimes with kerat

288 composed of more than 90% necrotic material admixed with few macrophages and viable cells at their o

289 nsisted of irradiated autologous tumor cells admixed with GM-CSF-secreting bystander cells.

290 r lymphoma (FL), malignant B cells are found admixed with heterogeneous lymphoid-like stromal cells w

291 ng injection of geminin-overexpressing cells admixed with MSCs/CAFs grew faster, metastasized earlier

292 We found that mucin, either admixed with or separately injected with the challenge b

293 h Anatolian and South-East European ancestry admixed with people in the Near East.

294 ulations, immunization using CoPoP liposomes admixed with recombinant RBD induces multiple orders of

295 alt tetra-n-butylammonium fluoride is simply admixed with the conjugated polymer poly(N,N'-bis(7-glyc

296 providing direct evidence that the Crusaders admixed with the local population.

297 Furthermore, when admixed with tumor cells, CD11b(+)Gr-1(+) cells from tum

298 sfected with green fluorescent protein (GFP) admixed with wild-type HeLa cells at ratios of 1:10(4) t

299 an populations are descended from, or highly admixed with, members of a subsequent migration event.

300 of recombinant RBD into particulate form via admixing with liposomes containing cobalt-porphyrin-phos