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2 onal region and alternative splicing, and of adoptively administering them to patients with relapsed
3 MOG-specific CD8 T cells could also suppress adoptively induced disease using wild-type MOG35-55-spec
4 proach for ovarian and other tumors in which adoptively infused gammadelta T cells are targeted using
5 fector memory T (Tem) cells were transferred adoptively to allergen-sensitized animals before allerge
6 Using allotype markers, it is possible to adoptively transfer memory B cells into a naive mouse an
8 tch, we compared the therapeutic efficacy of adoptively transfer Treg with or without donor specifici
10 r protection of nude mice was achieved using adoptively transferred 1.0 and 0.1 million, but not 0.01
12 man islet cells under the kidney capsule and adoptively transferred 5 x 10(6) splenocytes from 6-week
14 mation and goblet cell hyperplasia driven by adoptively transferred Ag-specific CD4(+) Th2 cells.
15 rejection and augmented the proliferation of adoptively transferred alloantigen-specific CD4(+) T cel
17 bnAb-engineered primary mouse B cells can be adoptively transferred and vaccinated in immunocompetent
19 lated significantly greater proliferation of adoptively transferred antigen-specific CD8(+) T cells i
21 l was carried out to evaluate the ability of adoptively transferred autologous T cells transduced wit
22 o 70% of patients with melanoma who received adoptively transferred autologous tumor-infiltrating lym
27 ion profiles of other chemokine receptors of adoptively transferred BLT1(+)/(+) and BLT1(-)/(-) CD8(+
29 ptor CCR2; 2) compared with CCR2(+/+) cells, adoptively transferred CCR2(-/-) bone marrow-derived DCs
32 28 also enhanced the suppressive capacity of adoptively transferred CD4(+) nTregs by increasing the s
35 -infiltrating myeloid cells is important for adoptively transferred CD8(+) cytotoxic T cells to destr
36 intravascular adhesion and extravasation of adoptively transferred CD8(+) effectors that is indispen
37 imal expansion, trafficking, and function of adoptively transferred CD8(+) T cells are parameters tha
41 and TLR/CD40 agonists augmented expansion of adoptively transferred CD8(+) T cells, delayed tumor gro
44 ipient mice supported the rapid expansion of adoptively transferred CD8+ T cells against melanoma.
46 d humans correlates with both a high dose of adoptively transferred cells and cells with a minimally
49 ith or without cotransplanted kidneys and/or adoptively transferred cells from long-term tolerant (LT
50 wine received class I mismatched kidney with adoptively transferred cells from LTT SLA(dd) recipients
51 in the spleen (where a major portion of the adoptively transferred cells homed) and in the eyes, whe
52 henotypic and functional characterization of adoptively transferred cells in ACT-responsive and nonre
53 lds promise to increase the effectiveness of adoptively transferred cells in both experimental and cl
54 t the lifespan, safety, and functionality of adoptively transferred cells in the presence of autologo
56 T-cell expansion improved the persistence of adoptively transferred cells, reduced tumor growth, and
60 f T cell tolerogenesis, we further show that adoptively transferred central but not effector memory T
61 e clinical efficacy and anatomic location of adoptively transferred chemokine receptor-deficient CD4(
63 hermore, immune reconstitution included both adoptively transferred clonotypes and endogenous clonoty
65 tive optical control of Ca(2+) signalling in adoptively transferred CTLs enhances T cell activation a
68 Strikingly, we found that the activity of adoptively transferred DGKzeta(-/-) T cells relied partl
69 ressing the diabetogenic AI4 T-cell receptor adoptively transferred disease to otherwise unmanipulate
71 curs in the presence of rapamycin or whether adoptively transferred donor Th9 cells would augment or
74 engineered T cells to overexpress TRAIL and adoptively transferred donor-type unsorted TRAIL+ T cell
76 d that persistence and antitumor activity of adoptively transferred effector T cells deficient in TGF
78 k macrophage dynamics in dysferlinopathy, we adoptively transferred enhanced green fluorescent protei
85 ivo microscopy corroborated proliferation of adoptively transferred hematopoietic progenitors in the
88 CID/IL2Rg(null) mice, but the persistence of adoptively transferred HSPC-NK cells was not affected.
92 cial pathogenic role played by IL-21 in T1D, adoptively transferred IFN-gamma-deficient CpG-proBs did
95 the proliferation of the allospecific Tregs adoptively transferred in an antigen-dependent manner.
96 revent graft-versus-host disease (GVHD) when adoptively transferred in murine models of hematopoietic
97 CD86, in expansion and antitumor efficacy of adoptively transferred in vitro-primed CD8(+) T cells re
100 bakeri-infected mice prevented colitis when adoptively transferred into a murine model of inflammato
101 Lastly, MZ, but not follicular, B cells adoptively transferred into B-cell-deficient muMT mice r
102 s plus B-cell-depleted wild-type splenocytes adoptively transferred into B-cell-deficient muMT mice r
103 el was established whereby DsRedOTI-Tc cells adoptively transferred into B6 mice bearing either a ova
105 cs of CD4-mediated help, CD4(+) T cells were adoptively transferred into CD4-deficient mice at variou
106 entiation under these conditions, cells were adoptively transferred into CD8-deficient mice, and lung
107 Monoclonal T. gondii-specific CD8 T cells adoptively transferred into coinfected mice recapitulate
109 ed with cytokines (GM-CSF, IL-4, IL-33) were adoptively transferred into eosinophil-deficient recipie
110 when FcgammaR(+/+) dendritic cells (DCs) are adoptively transferred into FcgammaR(-/-) mice, uptake a
113 city to MYHCA acquired a Treg phenotype when adoptively transferred into infarcted mice, which mediat
117 om unstressed control mice were isolated and adoptively transferred into naive lymphopenic Rag2(-/-)
121 hermore, p47(phox-/-) DCs pulsed with Lm and adoptively transferred into naive WT mice elicited Ab ti
123 ts with undetectable plasma viral loads were adoptively transferred into NOD.Cg-Prkdc(scid)Il2rg(tm1W
124 ogenic than their wild-type counterpart when adoptively transferred into NOD.Rag1(-/-) recipients, ev
127 1(-) thymocytes from Rag1((-)/(-)) mice were adoptively transferred into Rag1((-)/(-))Ly5.1 congenic
128 d capable of inducing stromal keratitis when adoptively transferred into Rag1(-/-) mice, with 95% of
129 of miR-15b/16 in conventional CD4(+) T cells adoptively transferred into Rag2(-/-) mice increased the
130 , which could by themselves mediate AHR when adoptively transferred into Rag2(-/-); Il2rg(-/-) mice t
132 genic cells specific to hen egg lysozyme are adoptively transferred into recipients that express hen
135 ulation responsible, primed CD8 T cells were adoptively transferred into tumor-bearing immunocompromi
141 t of infection from a high-dose inoculum, we adoptively transferred large numbers of T cells that wer
142 roscopy of lymph node explants revealed that adoptively transferred lymphocytes accumulated at lympha
144 Fluorescent imaging analyses revealed that adoptively transferred M2r macrophages specifically home
147 d in C57BL/6J-Kit(W-sh/W-sh) mice containing adoptively transferred mast cells that were either wild
151 was assessed by quantifying proliferation of adoptively transferred monoclonal T-cell receptor transg
152 experiments revealed that the recruitment of adoptively transferred monocytes and neutrophils to the
153 sed expression within primary tumors, as the adoptively transferred MSC develop carcinoma-associated
160 e immune milieu, CTX preconditioning allowed adoptively transferred naive tumor-specific CD4+ T cells
164 o optimize the in vivo cytokine milieu where adoptively transferred NK cells compete with other lymph
166 poxia, and transgenic expression of IL-15 in adoptively transferred NKT cells dramatically enhanced t
168 to augmenting both endogenous leukocytes and adoptively transferred ones by informing specificity, in
169 le, we show that CD154 expression identifies adoptively transferred or endogenous Ag-specific CD4(+)
172 gely abrogated the proliferative response of adoptively transferred OVA peptide-specific-transgenic C
174 jection, we used a transgenic model in which adoptively transferred ovalbumin (OVA)-specific cytotoxi
179 y, we evaluated the antileukemia activity of adoptively transferred polyclonal cancer antigen-reactiv
180 e mouse spleen and promoted the migration of adoptively transferred pre-activated B cells to the T/B
181 knock-in mice (termed HKIR) were relieved in adoptively transferred recipients in the presence of Sle
187 pled to inadequate cardiac commitment of the adoptively transferred stem cells compromises the improv
191 n epigenetic regulation impeding efficacy of adoptively transferred T cells and other approaches that
192 results in increased antitumor immunity when adoptively transferred T cells are presensitized, but de
193 is shown that effector cytokines secreted by adoptively transferred T cells expressing a chimeric Ag
197 esponse and may help prevent inactivation of adoptively transferred T cells thereby improving therape
198 cell surface marker for in vivo tracking of adoptively transferred T cells using both flow cytometry
200 e control of cytotoxic effector functions of adoptively transferred T cells with outstanding spatial
202 hich host tumor Ag cross-presentation primes adoptively transferred T cells, which remain functional
220 tide injection, in vivo Helios expression in adoptively transferred TCR transgenic T cells was more r
221 activation, proliferation, and expansion of adoptively transferred TEa cells in an Ag-specific manne
224 In this study, we show that activation of adoptively transferred Th cells during primary influenza
227 h2-, or IL-17-producing CD4(+) T cells, were adoptively transferred to APP/PS1 mice at 6 to 7 mo of a
228 ) T cells from Il17a fate-mapping mice, were adoptively transferred to assess their persistence in ge
230 endritic cells cultured with SA-IVIg or IVIg adoptively transferred to mice before OVA challenge indu
231 purified graft-reactive CD4CD25 T cells were adoptively transferred to mice-bearing skin allograft.
234 In gain-of-function experiments, B-1a cells, adoptively transferred to muMT mice with EAE, restored t
237 erior activity against tuberculosis could be adoptively transferred to naive, syngeneic mice by CD4(+
241 have demonstrated impressive responses when adoptively transferred to patients with advanced chronic
243 cells were sorted by flow cytometry and were adoptively transferred to recipient mice through tail ve
244 cells specific to hen egg lysozyme (HEL) are adoptively transferred to recipients and induce inflamma
245 e, T cell-dependent myeloma control could be adoptively transferred to secondary recipients and was m
246 against EAE when A2AAR(-/-) lymphocytes were adoptively transferred to T cell-deficient A2AAR(+/+) mi
247 yte-restricted adiponectin gene promoter was adoptively transferred to wild-type recipient mice.
248 have evolved from a hypothetical mediator of adoptively transferred tolerance to a well-defined popul
250 PC survival niches and their functioning, we adoptively transferred traceable Blimp-1-(GFP) PCs into
254 tion and expansion and/or persistence of the adoptively transferred tumor antigen-specific T cells in
256 the survival and effector differentiation of adoptively transferred tumor-reactive CD8(+) T-cells.
257 mediated expansion and antitumor efficacy of adoptively transferred tumor-specific CD8(+) T cells wer
260 ring effector phase of chronic infection, we adoptively transferred virus-specific day 8 effector CD8
262 has demonstrated the safety and efficacy of adoptively transferred virus-specific T cells for the pr
263 miquimod-treated skin of CCR6(-/-) mice, but adoptively transferred wild-type (CCR6(+/+)) gammadeltaT
266 cell function was investigated in Rag1 mice adoptively transferred with alloprimed IgG1 B cells.
267 In RAG(-/-) recipients of skin allografts adoptively transferred with CD4(+) T cells, we show that
269 In addition, the recipient mice that are adoptively transferred with JKAP-knockout T cells show e
270 xaggerated response in DeltaLC mice could be adoptively transferred with liver CD49a(+) NK cells.
272 equently, STING(-/-) mice, or wild-type mice adoptively transferred with STING(-/-) bone marrow, are
277 However, Nfil3/Rag1 double-knockout mice adoptively transferred with wild-type CD4(+) T cells dev
278 ID mice but did occur in SCID mice that were adoptively transferred with wild-type T cells, indicatin
280 in part due to increased M2 macrophages, we adoptively transferred wt macrophages into Cd14(-/-) mic
281 ce were almost completely protected from the adoptively transferred, aggressive form of T1D caused by
284 tantly, induced genetic deletion of Orai1 in adoptively transferred, MOG-specific T cells was able to
285 allergic airway inflammation (AAI) driven by adoptively transferred, traceable ovalbumin-experienced
286 cells exclusively generated B-1a cells when adoptively transferred, whereas sorted CD93(+)IgM(+)CD5(
289 ent T-cell alterations, could be restored by adoptively transferring CCR8-expressing monocytes/macrop
290 cDC-mediated induction pulmonary allergy by adoptively transferring house dust mite (HDM)-pulsed bon
291 nd that providing an accelerated response by adoptively transferring large numbers of antiviral T cel
292 se inhibitor Nor-NOHA but were reproduced by adoptively transferring MDSC or injecting arginase 1 to
293 ion in a genetically deficient strain and by adoptively transferring NK cells into NK-deficient mice.
294 or effective antitumor immunity was shown by adoptively transferring purified CD27(low)KLRG1(+) NK ce
295 progressive depigmentation was evaluated by adoptively transferring purified Treg or using rapamycin
297 f regulatory T (Treg) cells was evaluated by adoptively transferring Treg cells from milk EPIT-treate
298 CD4 depletion was completely neutralized by adoptively transferring tumor-specific Foxp3(+) T cells.