ライフサイエンスコーパス: adrenergic receptor

1 rhomboid protease GlpG and the human beta(2)-adrenergic receptor.

2 M egress of HSPCs and leukocytes via beta(3)-adrenergic receptor.

3 gonist-GPCR complex of iodopindolol and beta-adrenergic receptor.

4 alently conjugated TIL region from the beta1-adrenergic receptor.

5 f the compound for beta(2)- over the beta(1)-adrenergic receptor.

6 such as GABA(B), adenosine A1- and alpha(2A)-adrenergic receptors.

7 I(Na), I(Kur), I(CaL), I(CaT), I(f) and beta-adrenergic receptors.

8 omorbid, which involves the activity of beta-adrenergic receptors.

9 tion of presynaptic TRPV1 channels by alpha2 adrenergic receptors.

10 logical inhibition of muscarinic and/or beta-adrenergic receptors.

11 ion describing this drug class at the alpha1-adrenergic receptors.

12 , and is induced upon the activation of beta-adrenergic receptors.

13 ne, histamine, melatonin, acetylcholine, and adrenergic receptors.

14 bine, consistent with contribution of alpha2 adrenergic receptors.

15 ile POMC neurons are inhibited via alpha2A - adrenergic receptors.

16 and could be reversed by antagonism of beta3 adrenergic receptors.

17 c function via activation of post-junctional adrenergic receptors.

18 teric modulation of the alpha1A- and alpha1B-adrenergic receptors.

19 that it was mediated by activation of alpha2 adrenergic receptors.

20 within a single subfamily, such as the nine adrenergic receptors.

21 obiota-dependent metabolite that signals via adrenergic receptors.

22 ptors, including alpha2A, alpha2B, and beta2-adrenergic receptors.

23 up-regulated Adrb2 (which encodes the beta2-adrenergic receptor), a process dependent on IL-12 and S

24 the host via interaction with multiple ARs (adrenergic receptors)-a class of key receptors that regu

25 and intra-BLA or systemic antagonism of beta-adrenergic receptors abolished both long-term pain-induc

26 or cervical ganglion (SCG) neurons expressed adrenergic receptors (activated by epinephrine) and the

27 ipocyte lipolysis by fasting (24 h) or beta3-adrenergic receptor activation by CL316, 243 (CL) increa

28 t, expended less energy in response to beta3-adrenergic receptor activation, and were more insulin re

29 Prolonged adrenergic receptor activation, however, has deleterious

30 Here we investigate the effect of chronic adrenergic receptors activation on excitation-contractio

31 odopsin (visual receptor), opioid receptors, adrenergic receptors, adenosine receptors, dopamine rece

32 We investigated adrenergic receptor (ADR) beta2 desensitization by admin

33 The alpha1D-adrenergic receptor (ADRA1D) is a key regulator of cardi

34 The beta1-adrenergic-receptor (ADRB1) antagonist metoprolol reduce

35 e encoding lactate transporter MCT2 and beta-adrenergic receptor ADRB2, are strongly (~20-fold) up-re

36 Subsequently, we identified the beta2 adrenergic receptor (ADRB2) as a downstream target for P

37 us study, the Gly16Arg genotype of the beta2-adrenergic receptor (ADRB2) gene did not influence the d

38 Sustained beta3 adrenergic receptor (ADRB3) activation simultaneously up

39 eiging response: cold temperatures and beta3-adrenergic receptor (Adrb3) agonists.

40 in glucose homeostasis with associated beta adrenergic receptor (ADRbeta) desensitization.

41 aluated the associations of gene variants in adrenergic receptors (ADRs) with GAD, with the involveme

42 P) with a regularly used long-acting beta(2)-adrenergic receptor agonist (LABA) is well documented.

43 or in combination with a long-acting beta2 -adrenergic receptor agonist (LABA) on GCM in the bronchi

44 rality were treated with the selective beta3 adrenergic receptor agonist CL 316, 243 and underwent me

45 o cold temperatures or treated with the beta-adrenergic receptor agonist CL316,243 and that its expre

46 Treatment with the beta3-adrenergic receptor agonist CL316,243 increased Cx43 exp

47 we report a role of Tregs in enhancing beta3-adrenergic receptor agonist CL316243 (CL)-stimulated the

48 In humans, the alpha2-adrenergic receptor agonist clonidine increases decisive

49 an also benefit from the addition of a beta2-adrenergic receptor agonist to their medication.

50 Salmeterol is a long-acting beta2-adrenergic receptor agonist used to treat chronic obstru

51 Significance statement: Clonidine, an alpha2-adrenergic receptor agonist, which decreases the level o

52 cardioprotective effects of an alpha-1A-AR (adrenergic receptor) agonist.

53 ial agonists (eg, buprenorphine), and alpha2-adrenergic receptor agonists (eg, clonidine and lofexidi

54 nic fat cells that can be activated by beta3-adrenergic receptor agonists.

55 ved with adrenergic function were genotyped; adrenergic receptors alpha(1A) (ADRA1A), alpha(2A) (ADRA

56 ial growth factor receptor, or the alpha (1)-adrenergic receptor (alpha (1)-AR).

57 The alpha(2a)-adrenergic receptor (alpha(2a)-AR) agonist guanfacine ha

58 ) mediate the post-Golgi export of alpha(2B)-adrenergic receptor (alpha(2B)-AR), a prototypic GPCR, a

59 We previously reported alpha(1D)-adrenergic receptors (alpha(1D)-ARs) - key regulators of

60 alpha(1D)-adrenergic receptors (alpha(1D)-ARs) - key regulators of

61 tagamma specificity of presynaptic alpha(2a)-adrenergic receptors (alpha(2a)ARs) in both adrenergic (

62 were prevented by incubation with the alpha1 adrenergic receptor (alpha1-AR) antagonist prazosin.

63 in vascular smooth muscle coordinates alpha1-adrenergic receptor (alpha1-AR) vasoconstriction and blo

64 vasopressin receptor (V1A-R) but not alpha1 adrenergic receptor (alpha1-AR), suggesting that GPCR pr

65 in dorsal raphe neurons is driven via alpha1-adrenergic receptors (alpha1-A(R)) activation.

66 imilarly, agonist stimulation of vPAG alpha1-adrenergic receptors (alpha1ARs) increased latency to fa

67 In contrast, activation of alpha1B-adrenergic receptors (alpha1B-ARs) induced transient inh

68 lutionary precursor to the vertebrate alpha2-adrenergic receptors (alpha2-ARs) based upon sequence si

69 gulation of cell surface transport of alpha2-adrenergic receptors (alpha2-ARs) by GGA3 (Golgi-localiz

70 rect interaction between APP and the alpha2A-adrenergic receptor (alpha2AAR) that occurs at the intra

71 A2) in the cell surface transport of alpha2B-adrenergic receptor (alpha2B-AR), a prototypic GPCR, and

72 rine, a catecholamine that binds to the beta-adrenergic receptor and activates the cAMP-PKA-dependent

73 ailure work by targeting GPCRs, such as beta-adrenergic receptor and angiotensin II receptor antagoni

74 dependent on both local activation of alpha-adrenergic receptors and modulation of T-type calcium ch

75 It is known that beta-adrenergic receptors and NA can boost LTP maintenance by

76 n dissociation from the alpha1A- and alpha1B-adrenergic receptors and noncompetitively inhibit recept

77 e unconsciousness selectively through alpha2-adrenergic receptors and related circuits.

78 ediastinum ratio, reflecting the function of adrenergic receptors and sympathetic activity, were posi

79 num ratio directly measuring the function of adrenergic receptors and sympathetic integrity (from the

80 unreported dissimilar ligands of the beta(2)-adrenergic receptor, and the optimization of one series

81 mpal LTP, decreased neuronal levels of beta2-adrenergic receptors, and activated microglia in wt mice

82 tested for the beta2-, alpha1-, and alpha2- adrenergic receptors, and adenosine type 1 receptor (A1R

83 beta-adrenergic receptor antagonism after experimental stroke

84 1 (CRF1) antagonist (antalarmin), and alpha2-adrenergic receptor antagonist (yohimbine; used as a pha

85 4 h or by intravenous infusion of the alpha-adrenergic receptor antagonist phentolamine for only 30

86 We probed the effects of the beta-adrenergic receptor antagonist propranolol (40 mg) using

87 We find that administration of the beta-adrenergic receptor antagonist propranolol before memory

88 The beta-adrenergic receptor antagonist propranolol, administered

89 Propranolol is a nonselective beta-adrenergic receptor antagonist that is efficacious in re

90 s increased by treatment with IL-4 or a beta-adrenergic receptor antagonist.

91 Orthosteric beta-adrenergic receptor antagonists, known as beta-blockers,

92 nonmotor symptoms of PD that were rescued by adrenergic receptor antagonists.

93 handgrip-exercise ischaemia (PEI) and beta1 -adrenergic receptor (AR) blockade.

94 ther organ thermogenesis occurs through beta-adrenergic receptors (AR), and considerable effort over

95 M noradrenergic innervation promotes beta(2)-adrenergic-receptor(AR)-interleukin-6-dependent megakary

96 Adrenergic receptors are mediators of adrenergic and nor

97 The alpha1-adrenergic receptors are targets for a number of cardiov

98 Adrenergic receptors are the primary target for GRK2 act

99 iprocal down-regulation occurs between beta1-adrenergic receptors (ARs) and the cardioprotective sphi

100 We find that activation of alpha(2A)-adrenergic receptors (ARs) by the agonist guanfacine red

101 Agonist-triggered downregulation of beta-adrenergic receptors (ARs) constitutes vital negative fe

102 regulatory loops via activation of distinct adrenergic receptors (ARs), and their ES-evoked activati

103 cular myocyte expresses all 5 of the cardiac adrenergic receptors (ARs), beta1, beta2, beta3, alpha1A

104 Noradrenaline acts through adrenergic receptors (ARs), of which beta2-adrenergic re

105 We focused on the beta (2)-adrenergic receptor, as it is currently the receptor wit

106 teracts with the BiOctR, DmOctR, and alpha2C-adrenergic receptor at an allosteric site.

107 a oligomers induce acute wakefulness through Adrenergic receptor b2 (Adrb2) and Progesterone membrane

108 The prototypical beta-2 adrenergic receptor (B2AR) activates Galpha stimulatory

109 LOBP has been attributed to beta(2)-adrenergic receptor (B2AR) downregulation, a process req

110 predicting activation pathways of the beta 2-adrenergic receptor (beta 2-AR), folding of the FiP35 WW

111 The beta(1)-adrenergic receptor (beta(1)-AR) is a major regulator of

112 lating a neuroprotective program via beta(2)-adrenergic receptor (beta(2)-AR) signaling and mediated

113 lphas and Galphaq C termini with the beta(2)-adrenergic receptor (beta(2)-AR), targeted at the G-prot

114 Clenbuterol, a beta(2)-adrenergic receptor (beta(2)AR) agonist enhances skeleta

115 ingle amino acid substitutions to the beta-2 adrenergic receptor (beta(2)AR) at four concentrations o

116 The beta(2) adrenergic receptor (beta(2)AR) is an archetypal G prote

117 The beta(2) adrenergic receptor (beta(2)AR) signals through both G(s

118 ics studies on ligand binding to the beta(2)-adrenergic receptor (beta(2)AR) suggested that ligands p

119 A human beta(2)-adrenergic receptor (beta(2)AR) was used to demonstrate

120 iophysical properties of a GPCR, the beta(2)-adrenergic receptor (beta(2)AR), in high-density lipopro

121 imary Gi/o-coupling receptor and the beta(2)-adrenergic receptor (beta(2)AR, which primarily couples

122 n receptor (GCGR; family B) with the beta(2) adrenergic receptor (beta(2)AR; family A).

123 beta-Adrenergic receptor (beta-AR) agonists are the most comm

124 timuli and the subsequent activation of beta-adrenergic receptor (beta-AR) potently stimulate adipose

125 rapies to improve heart function target beta-adrenergic receptor (beta-AR) signaling and Ca(2+) handl

126 We used beta-adrenergic receptor (beta-AR) signaling as a prototype t

127 tumor microenvironment is regulated by beta2-adrenergic receptor (beta-AR) signaling in host immune c

128 beta-Adrenergic receptor (beta-AR) signaling is a pathway con

129 Intracellular Ca(2+) ([Ca(2+) ]i ) and beta-adrenergic receptor (beta-AR) stimulation modulate IKs a

130 d in cardiac dysfunction during chronic beta-adrenergic receptor (beta-AR) stimulation.

131 s myocardial calcium transients through beta-adrenergic receptor (beta-AR)-mediated phosphorylation o

132 deubiquitinases regulate myocardial beta(1)-adrenergic receptors (beta(1)ARs) is unknown.

133 Agonists of beta(2) adrenergic receptors (beta(2)AR) and glucocorticoid rece

134 stimulates contractility by activating beta-adrenergic receptors (beta-AR).

135 ple conformational states of a phospho-beta2 adrenergic receptor/beta-arrestin-1(beta-arr1) membrane

136 We found that administration of the beta1-adrenergic receptor (beta1AR) blocker atenolol during CS

137 The beta1-adrenergic receptor (beta1AR) is a G protein-coupled rec

138 The beta1 adrenergic receptor (beta1AR) is recognized as a classic

139 re, we hypothesized that activation of beta1-adrenergic receptors (beta1ARs) localized to ghrelin cel

140 beta1-adrenergic receptors (beta1ARs) mediate catecholamine ac

141 t elevation of phosphorylation of the beta2 -adrenergic receptor (beta2 AR) at both the protein kinas

142 timulated by two Gs-coupled receptors, beta2-adrenergic receptor (beta2-AR) and D1 dopamine receptor

143 We demonstrate here a role for the beta2-adrenergic receptor (beta2-AR), which binds the stress m

144 to selective interactions between the beta2-adrenergic receptor (beta2-AR)-Galphas and V1A receptor

145 show in atomistic detail how the human beta2-adrenergic receptor (beta2AR) - a prototypical G protein

146 The beta-2 adrenergic receptor (beta2AR) agonist formoterol induces

147 pertrophy stimulated by clenbuterol, a beta2-adrenergic receptor (beta2AR) agonist, was significantly

148 beta2-adrenergic receptor (beta2AR) agonists are a mainstay of

149 PCL interacts with beta2-adrenergic receptor (beta2AR) and co-localizes with beta

150 The crystal structure of the beta2-adrenergic receptor (beta2AR) bound to the G protein ade

151 ipitated with overexpressed TPbeta and beta2-adrenergic receptor (beta2AR) in HEK 293 cells, but also

152 d that photoactivation of gelsolin and beta2-adrenergic receptor (beta2AR) optobodies suppressed endo

153 -15) is an allosteric modulator of the beta2 adrenergic receptor (beta2AR) that was recently isolated

154 aging, we examine TM6 movements in the beta2 adrenergic receptor (beta2AR) upon exposure to orthoster

155 ine 2B receptor (A2BR), but not of the beta2 adrenergic receptor (beta2AR), leading to an enhanced, a

156 n by comparing human Wntless (Wls) and beta2 adrenergic receptor (beta2AR), which require retromer ph

157 g to analyze GRK5 interaction with the beta2-adrenergic receptor (beta2AR).

158 3 in regulating the trafficking of the beta2-adrenergic receptor (beta2AR).

159 e find, however, that co-expression of beta2-adrenergic receptors (beta2AR) in HEK-293T routes TAS2R1

160 report here that a population of human beta2-adrenergic receptors (beta2AR), a canonical G protein-co

161 viously demonstrated the importance of beta2-adrenergic receptors (beta2ARs) in the regulation of imm

162 sed an active-state structure of the beta(2)-adrenergic receptor (beta2R) to build beta2R-WT and beta

163 BACKGROUNDMirabegron is a beta3-adrenergic receptor (beta3-AR) agonist approved only for

164 A robust change in abundance of the beta3-adrenergic receptor (beta3-AR) is observed in brown/beig

165 r ROS or antioxidant treatment affects beta3-adrenergic receptor (beta3-AR) stimulation-induced adipo

166 by the sympathetic nervous system via beta3-adrenergic receptors (beta3-AR).

167 Adipose tissue contains beta3-adrenergic receptors (beta3-ARs), and this study was int

168 o enhanced signaling through adipocyte beta3-adrenergic receptors (beta3-ARs), indicating that barr2

169 anisms underlying synaptic responses to beta-adrenergic receptor (betaAR) activation remain poorly un

170 population of Galphai and its coupled beta2-adrenergic receptor (betaAR), are localized to caveola d

171 Activation of the beta-adrenergic receptor (betaAR)/cAMP/protein kinase A (PKA)

172 beta-adrenergic receptors (betaARs) are critical regulators o

173 Beta adrenergic receptors (betaARs) are G-protein-coupled rec

174 h adrenergic receptors (ARs), of which beta2-adrenergic receptors (betaARs) are of particular importa

175 In heart failure, the beta-adrenergic receptors (betaARs) become desensitized and u

176 Activation of beta-adrenergic receptors (betaARs) enhances both the inducti

177 It is unclear whether cAMP generated by beta-adrenergic receptors (betaARs) is required for PF-PC LTP

178 n part, through chronic stimulation of beta1 adrenergic receptors (betaARs) on cardiac myocytes.

179 Stimulation of beta-adrenergic receptors (betaARs) provides the most efficie

180 norepinephrine, through its actions on beta-adrenergic receptors (betaARs), modulates aversive memor

181 d through the neuromodulatory action of beta-adrenergic receptors (betaARs).

182 lkaloids were evaluated for their opioid and adrenergic receptor binding and functional effects, in v

183 dilation) before and after local alpha+beta adrenergic receptor blockade (phentolamine and propranol

184 In contrast, during beta1 -adrenergic receptor blockade, LV apical rotation, twist

185 , ganglionic-blocker administration or beta2-adrenergic receptor blockade.

186 ing post-exercise ischaemia (PEI) and beta1 -adrenergic receptor blockade.

187 to characterize the appropriate use of beta-adrenergic receptor blockers (beta-blockers) in the cont

188 s that target neurohormonal activation: beta-adrenergic receptor blockers (beta-blockers), ACE (angio

189 lies on pharmacological therapy, mostly beta-adrenergic receptor blockers (specifically, propranolol

190 The structures of beta2-adrenergic receptor bound with a variety of ligands prov

191 y denervation or pharmacological blockade of adrenergic receptors, but not by chemical sympathectomy

192 nse hormone norepinephrine to stimulate beta-adrenergic receptors, cAMP production, and protein kinas

193 ling dogma holds that activation of the beta-adrenergic receptor/cAMP/protein kinase A signalling pat

194 Upon agonist stimulation, alpha1B-adrenergic receptors couple to Gq proteins, calcium sign

195 the delta-opioid receptor, but not the beta2-adrenergic receptor, defining a role for CLCs in the upt

196 d by acute treadmill exercise through a beta-adrenergic receptor-dependent mechanism.

197 e increases SKM D2 expression through a beta-adrenergic receptor-dependent mechanism.

198 s produced from brown adipocytes in a beta-3-adrenergic-receptor-dependent fashion.

199 nalysis suggests that activation of the beta-adrenergic receptor either via canonical (Gs-coupled) or

200 ynaptic plasticity, while activation of beta-adrenergic receptors elevates cAMP levels and modulates

201 tu hybridization to detect the expression of adrenergic receptor-encoding mRNA in the inferior collic

202 ortions of cells in the IC that expressed no adrenergic receptor-encoding mRNA, alpha1 and alpha2A ad

203 c receptor-encoding mRNA, alpha1 and alpha2A adrenergic receptor-encoding mRNA, and alpha1, alpha2A,

204 amyloid precursor protein modulates alpha2A-adrenergic receptor endocytosis and signaling through di

205 in the IC and provide the first evidence for adrenergic receptor expression and co-expression in the

206 These data suggest a coordinated pattern of adrenergic receptor expression in the IC and provide the

207 Using the beta-adrenergic receptor family as a model, we demonstrate th

208 s in a challenging way, we chose the beta(2)-adrenergic receptor, for which a large number of ligands

209 vation is abolished by deletion of alpha(1A)-adrenergic receptor from astroglia, indicating that nore

210 y reflecting down-regulation of cardiac beta-adrenergic receptor function in chronic hypoxia.

211 rescent proteins and four GPCRs: the alpha2A-adrenergic receptor, GABAB, cannabinoid receptor type 1

212 cently labeled Galphai1 subunits and alpha2A-adrenergic receptor, GABAB, or dopamine receptor type 2

213 We have identified a mutation in the beta(1)-adrenergic receptor gene in humans who require fewer hou

214 an architecture similar to that of the beta2-adrenergic receptor-GS complex, including a flexible alp

215 s (GPCRs), such as rhodopsin and the beta(2) adrenergic receptor, have provided a picture of how stru

216 and active experimental structures of beta2 adrenergic receptor (hbeta2AR) and M2 muscarinic acetylc

217 crystal structure of the prototypic beta(2)-adrenergic receptor in complex with an orthosteric agoni

218 nsistent with the crystal structure of beta2 adrenergic receptor in complex with Gs Conformational ch

219 onto the extracellular domain of the Beta-2 adrenergic receptor in HEK293T cells, followed by incuba

220 al regulator of signaling downstream of beta-adrenergic receptors in cardiomyocytes.

221 eatly reduced, suggesting that activation of adrenergic receptors in DRG neurons is preferentially li

222 ese effects required the presence of beta(2)-adrenergic receptors in microglia.

223 because of, for example, activation of beta1-adrenergic receptors in myocardium.

224 activation of excitatory alpha1A - and beta- adrenergic receptors in NPY/AgRP neurons, while POMC neu

225 Sympathetic stimulation of beta-adrenergic receptors in response to cold induces prolife

226 ults highlight the important role of beta(1)-adrenergic receptors in sleep/wake regulation.

227 have provided evidence for the expression of adrenergic receptors in the midbrain auditory nucleus, t

228 er studies using mice lacking beta2AR (beta2 adrenergic receptors) indicate that beta2AR in the bone

229 ipogenesis and adult deletion enhances beta3-adrenergic-receptor-induced beige adipocyte formation.

230 adrenergic stress or signaling through beta-adrenergic receptor is reduced.

231 ERK1/2 activation through activation of beta-adrenergic receptor kinase 1.

232 tagamma sink betaARK1-ct (C terminus of beta-adrenergic receptor kinase-1) was coexpressed with TRPM3

233 so reversed by an inhibitory peptide to beta-adrenergic receptor kinase.

234 phosphorylating the LTB4 receptor using beta adrenergic receptor kinase.

235 dothelial Adrb2, the gene encoding the beta2-adrenergic receptor, leads to inhibition of angiogenesis

236 s previously not been described for beta (2)-adrenergic receptor ligands, and one of them shows an in

237 evant responses was corroborated using beta2-adrenergic receptor ligands.

238 cardiac autonomic function and damage to the adrenergic receptors may contribute to the development o

239 Additionally, we report that beta-adrenergic receptors mediate the anxiety-like phenotype

240 ectrical stimulation (PNES) resulted in beta-adrenergic receptor-mediated-accumulation of B and T cel

241 ambs, IUGR lambs and IUGR lambs treated with adrenergic receptor modifiers: clenbuterol atenolol and

242 have been associated with IgGs against beta2-adrenergic receptor, muscarinic-2 receptors, AChR-nicoti

243 l of arousal by selectively targeting alpha2 adrenergic receptors on LC neurons, resulting in reduced

244 ularis and norepinephrine signaling to beta2 adrenergic receptors on MMs.

245 ycling by activation of alpha1- and/or beta3-adrenergic receptors or the SERCA2b-RyR2 pathway stimula

246 ssociated with significant changes in beta2 -adrenergic receptor phosphorylation at protein kinase A

247 released by sympathetic nerves can activate adrenergic receptors present on nearly every cell type,

248 raffic were investigated by studying alpha1B-adrenergic receptor-Rab protein interactions, using Fors

249 Pharmacologic stimulation of beta(2)-adrenergic receptors recapitulated these observations an

250 aarr1 in complex with M2 muscarinic or beta2-adrenergic receptors reconstituted in lipid nanodiscs ac

251 Stress hormone signaling through beta-adrenergic receptors regulates macrophage mechanotype an

252 mediated by ET(A), thromboxane, and alpha(2)-adrenergic receptors, respectively, and were insensitive

253 rown adipocytes, displayed an impaired beta3-adrenergic receptor response that was characterized by a

254 gnaling profiles of 28 variants of the beta2-adrenergic receptor reveals three clearly distinct pheno

255 able to normalize the distribution of beta2 adrenergic receptor signal by preventing PKA signal acce

256 further demonstrate that the endosomal beta2-adrenergic receptor signal confers uniformity on the dow

257 mpacts of high-fat diet (HFD) on the insulin-adrenergic receptor signal network in hearts.

258 e recently uncovered an insulin receptor and adrenergic receptor signal network in the heart.

259 myofilaments is because of an enhanced beta2 adrenergic receptor signal selectively directed to the m

260 ction of caveolin-3 is able to confine beta2 adrenergic receptor signaling and restore myocyte contra

261 rabbit myocytes, selectively enhanced beta2 adrenergic receptor signaling toward the myofilaments co

262 ostate cancer, we show that endothelial beta-adrenergic receptor signaling via adrenergic nerve-deriv

263 angiotensin aldosterone signaling and beta-2 adrenergic receptor signaling.

264 function and is mediated, in part, by beta1-adrenergic receptor signaling.

265 d in HF patients, causing dysfunctional beta-adrenergic receptor signaling.

266 brown adipocytes through modulation of beta-adrenergic receptor signaling.

267 n this process and the importance of beta(2)-adrenergic receptor signaling.

268 fat diet (HFD) feeding on the cardiac beta2 -adrenergic receptor signalling and the impacts on cardia

269 ronic cold adaptation in the absence of beta-adrenergic receptor signalling.

270 r the same receptor molecule (e.g., the beta-adrenergic receptor), some agonists have a propensity to

271 tics(3,4), cell ablation and knockout of the adrenergic receptor specifically in melanocyte stem cell

272 Three predicted mutations in beta(2)-adrenergic receptor stabilize binding of noncognate Galp

273 ng method to study the effects of acute beta-adrenergic receptor stimulation (through isoproterenol (

274 myocardial function was unchanged, but beta-adrenergic receptor stimulation of cardiac inotropy, cAM

275 out which signals activate BA, besides beta3-adrenergic receptor stimulation, is limited.

276 is a key negative regulator of cardiac beta-adrenergic receptor stimulation.

277 d combined influences of beta(1)-AR (beta(1)-adrenergic receptor) stimulation and peripheral O(2) sat

278 -coupled receptor (GPCR) and the predominant adrenergic receptor subtype in the heart, where it media

279 certain the modulatory potential of multiple adrenergic receptor subtypes in a single IC cell, we mea

280 When alpha1B-adrenergic receptors that had been mutated at protein ki

281 ands and investigated their impacts on beta2-adrenergic receptor through a total of 12 x 100 ns molec

282 ts with adenosine A1, GABA(B), and alpha(2A)-adrenergic receptors, through a mechanism involving both

283 through signaling pathways identical to beta-adrenergic receptors, thus providing support that inhibi

284 transmembrane helices 6 and 7 of the beta(1)-adrenergic receptor to agonist stimulation and coupling

285 NE enhances thermogenesis through beta3-adrenergic receptors to activate brown adipose tissue an

286 from impaired signal transduction from beta-adrenergic receptors to adenylate cyclase.

287 acological ablation of sympathetic nerves or adrenergic receptors to assess their relevance for rhyth

288 ular populations that express different beta-adrenergic receptors to induce beige adipogenesis.

289 gest that protein kinase C modulates alpha1B-adrenergic receptor transfer to late endosomes and that

290 silon in response to the stimulation of beta-adrenergic receptors, translocating the complex to the p

291 Activation of glial alpha1-adrenergic receptors triggers rapid astrocytic Ca(2+) el

292 eas gene expression of ADRB1 (encoding beta1-adrenergic receptors) was decreased at ZT14 versus ZT4 i

293 for a set of small molecules with the beta2 adrenergic receptor, we demonstrate that deconvolution o

294 ng (13)C methyl methionine NMR for the beta1-adrenergic receptor, we identify ligand efficacy-depende

295 We observed that the content of beta2-adrenergic receptors, which are mainly expressed in skel

296 s also shown to be a modulator of the alpha1-adrenergic receptors, which suggests a general lack of s

297 higher affinity at opioid receptors than at adrenergic receptors while the vice versa was observed f

298 ction that a complete antagonist of the beta-adrenergic receptor will likely block long-lasting LTP i

299 y, of a single active human chimeric beta(2)-adrenergic receptor with the C-terminal tail of the argi

300 Stimulation of Galphas-coupled beta-adrenergic receptors with isoproterenol induced PKA-depe