1  of reactions leading to the colored product adrenochrome.

2 ng the oxidized and cyclized norepinephrine, adrenochrome, and YhdA is capable of reducing a number o

3            Employing enzymatic studies using adrenochrome as a substrate, we show that quinone reduct

4 cies, nitric oxide and O2.-, we employed the adrenochrome assay to examine whether nNOS was capable o

5 pinephrine, the quinone cyclizes quickly and adrenochrome formation dominates, but for dopamine, the

6 , both superoxide formation and the yield of adrenochrome increase at higher pH.

7                                 The yield of adrenochrome increases if the epinephrine semiquinone re

8 re reversed, generation of potentially toxic adrenochromes is reduced, and survival rate is improved.

9                              We also use the adrenochrome test as an indicator of ROS in vitro in the

10 sely related to the plasma concentrations of adrenochromes, the product of the autoxidation of catech

11 e reductase 2 in complexes with dopamine and adrenochrome, two compounds that are structurally relate

12 reductase 2 is specific for the reduction of adrenochrome, whereas quinone reductase 1 shows no activ