ライフサイエンスコーパス: affect

1 sue contexts and plausible target genes they affect.

2 notropic polypeptide, were not as profoundly affected.

3 under which stability of a population may be affected.

4 high mortality and morbidity rates for those affected.

5 of how sex ratios of organisms with TSD are affected.

6 Canine diabetes mellitus (DM) affects 0.6% of the canine population and yet, its etiol

7 the most prevalent liver disease worldwide, affecting 20%-25% of the adult population.

8 scovery of the first pharmaceutical strongly affecting 3D genome organization.

9 rypanosoma cruzi, is a public health problem affecting 6 to 8 million people, mainly in Latin America

10 eath burden as prevalence continues to rise, affecting 6%-13% of the global population.

11 Pembrolizumab-related adverse events affected 71% of the patients, and 4 (7%) were grade >= 3

12 CVD affects a significant proportion of the population globa

13 Taken together, results showed that ethanol affects activation, recruitment, phagocytosis and killin

14 rough a Comprehensive Care Continuum for HIV-affected Adolescents in Resource Constrained Settings (P

15 prostate, is among the most common diseases affecting aging men, but the underlying molecular featur

16 Depression affects all aspects of an individual's life but evidence

17 n of genomic DNA into nucleosomes profoundly affects all DNA-related processes in eukaryotes.

18 sy (MTLE) is a chronic neurological disorder affecting almost 40% of adult patients with epilepsy.

19 Egg allergy affects almost 1 in 10 Australian infants.

20 A site usage, epigenetic factors potentially affect alternative polyadenylation (APA).

21 VdAtf1 affects ammonium and nitrate assimilation in response to

22 pa opioid receptor system modulates negative affect and dysphoria, but recent studies now implicate t

23 We model the chromatin of the affected and control cells as networks and analyze the n

24 Fluorescein angiograms of the affected and fellow eyes were reviewed by 2 authors for

25 Methane effluxes were higher in fire-affected areas (7.8 +/- 2.2 mg CH(4) m(-2) hr(-1) ) comp

26 effective, grafted neurons should migrate to affected areas at a faster rate.

27 opioid system in the modulation of negative affect associated with pain.

28 gy, disturbs mitochondrial Ca2+ homeostasis, affects ATP production, and attenuates DNA repair.

29 is known about how sensorimotor integration affects auditory perception.

30 d, and analyzed to determine how supervisors affect autonomy of residents.

31 tion and the role of soluble proteoglycan in affecting autophagy and angiogenesis.

32 The condition affects between 5% and 10% of otherwise healthy individu

33 Disease-causing sequence variants often affect binding residues.

34 odel, integration in S. calendulacea did not affect biomass of the parasitized ramet, decreased bioma

35 Across surveys, tree diversity noticeably affected bird responses, demonstrated by significantly h

36 g development or treatment regimens that may affect both acute and long-term effects of manipulating

37 roduce disease in humans of all ages and can affect both pulmonary and extrapulmonary sites.

38 condary structure appeared to be key factors affecting both cheese microstructure and properties.

39 s) accrete in the brain during childhood and affect brain development.

40 only believed to be peripherally restricted, affect brain oxygen responses induced by intravenous her

41 ologically affected vessels of human CADASIL-affected brains.

42 he Opa1 (+/-) photoreceptors was not greatly affected, but the mitochondria were enlarged and had red

43 geneous properties of the human femoral head affected by a disease such as osteoarthritis.

44 In addition, the GBM is affected by acquired autoimmune disorders and metabolic

45 nd robust parameters that are unlikely to be affected by aneurysm formation could aid in risk stratif

46 t that species colonization is more strongly affected by biotic resistance from residents than 3 degr

47 duction of pro-inflammatory mediators is not affected by C/EBPgamma.

48 that population growth can be substantially affected by changes in traits that are variable under en

49 mean free path of the charge carriers and is affected by crystal structure, scattering from boundarie

50 to subcortical brain structures, which were affected by deletion size and psychotic illness.

51 The performance of the AI system was not affected by disease prevalence (93% accuracy for common

52 inants whose photochemical transformation is affected by dissolved organic matter (DOM).

53 ork to identify neurodevelopmental processes affected by diverse risk variants for SCZ and ASD and el

54 g that somatic sexual differentiation may be affected by external conditions.

55 ncluding microbes and invertebrates, was not affected by fire.

56 rldwide, the interpretation of mammograms is affected by high rates of false positives and false nega

57 ends in the location of transfection are not affected by injury.

58 ber of fibres; and (iii) percentage of tract affected by lesions were computed for each connecting tr

59 ns showed that mobility in plaque domains is affected by mobility of the Cx proteins.

60 not known whether such neuroadaptations are affected by number of days of alcohol abstinence and whe

61 The brainstem has been shown to be affected by photoperiodic changes, and that longer photo

62 and identify regions that are significantly affected by recurrent breakpoints and recurrent somatic

63 ncoding multiple TMDs was disproportionately affected by RPLP1/2 knockdown, implying a role for RPLP1

64 We find that lake stability is affected by species richness and lake size in both ecore

65 ies dramatically for different fluids and is affected by system pressure, surface roughness, and liqu

66 sis, being both free and bound forms equally affected by temperature.

67 virus (RVFV) in livestock in an area heavily affected by that outbreak.

68 recipitously, with countries worldwide being affected by the pandemic to a similar degree.

69 s period of peri-implantitis, which could be affected by the restoration emergence angle.

70 , calligraphic, or medical images), and less affected by the sample size, suggesting that the optimal

71 n that P450s profiles in these organisms are affected by their lifestyle.

72 nosis and clinical assessment in individuals affected by these disorders.

73 s the expressions of both HO-1 and P450s are affected by xenobiotic exposure, changes in HO-1 express

74 known about how reactive Fe and Al minerals affect C cycling in restored wetlands.

75 he hypothesis that human immunoglobulins may affect C. neoformans virulence in vivo warrants further

76 Our data show human IgM affects C. neoformans morphology in vitro and suggest th

77 ration by restoring Sox10 expression without affecting canonical HIF1a activity.

78 ciation studies (GWASs) including 55,105 CRC-affected case subjects and 65,079 control subjects of Eu

79 We also showed that MBNL3 and KANSL2 do not affect cell proliferation.

80 on procedures required for phosphoflow often affect cell surface epitopes or mAb conjugates, precludi

81 The experimental whitening gels did not affect cell viability.

82 in unique histone methylation signatures in affected cell populations, including repressive H3K9me3

83 l morphologies, biochemical composition, and affected cell types seen across these disorders.

84 ocytic differentiation without significantly affecting cell proliferation, cell death, or UPR inducti

85 identified how the Toxoplasma effector GRA15 affects cell-autonomous immunity in human and murine cel

86 impaired response to mitochondrial stress in affected cells.

87 ells to the different nanoparticles modestly affects cellular metabolic activity.

88 unced effect in the RAS-B system, while flow affected certain coral response variables in the FTS tan

89 A UbV targeting Ube2D1 did not affect charging but greatly attenuated chain elongation.

90 istological exam of a foot amputated from an affected child revealed complete absence of skeletal mus

91 of the DNA-binding-deficient mutant of NuMA affects chromatin decondensation at the mitotic exit, an

92 acronutrient composition of high-fiber diets affects circulating SCFAs, which are associated with mea

93 racts with beta-2-microglobulin (beta2M) and affects class I Ag presentation through sequestration of

94 dification systems, including the ability of affecting clinically relevant phenotypes such as virulen

95 locumab added to a background statin did not affect cognitive performance in a subset of 1,204 patien

96 lt in significant morbidity and mortality in affected countries.

97 intervals compared with some other seriously affected countries.

98 Climate change is expected to affect crop production worldwide, particularly in rain-f

99 nomolar affinity and block MIF/CXCR4 without affecting CXCL12/CXCR4.

100 There are limited data on how such anomalies affect deaths from injuries.

101 the magnitude of anorexia (e.g., via drugs) affect disease dynamics and virulence evolution.

102 NAD(+) levels also affect DNA repair capacity as NAD(+) is a substrate for

103 We discuss how these errors have affected downstream analyses and give recommendations fo

104 cts high-order regions of the brain, but may affect earlier stages of cognitive processing.

105 ar the sensorimotor network, also tend to be affected early during premanifest stages.

106 le about how changes in winter snowfall will affect ecosystem productivity and plant community struct

107 y HDAC1 in GBM core cells which subsequently affect edge cells by secreting the soluble form of CD109

108 he father and mother, but not of the zygote, affects embryonic viability and growth during gestation.

109 We present how chamber background pressure affects energetic proton acceleration from an ultra-inte

110 SNX19 transcripts, whereas they only weakly affected expression of an exon-exon junction that tags t

111 Each of the drugs affected expression or activity of their predicted targe

112 es) correlated significantly with numbers of affected families (but not for dominant disease).

113 anxiety disorders transmission in clinically affected families.

114 not only for the patient but especially for affected family members.

115 Pain-induced defensive behaviors affecting fitness have also been reported in crustaceans

116 rives the allocation of bacterial resources, affecting, for example, the expression levels of protein

117 in individual sarcomeres within a myofibril affects force production.

118 he disordered ensembles of foldable proteins affect function in vivo.

119 5/GAK/DGKQ locus, which could be mediated by affecting GCase activity.

120 riants, which underlie genetic loci known to affect gene expression.

121 These allele-specific CNAs affect genomic regions containing well-known breast-canc

122 ies and irrigation management, which in turn affect genotypic rankings of transpiration in a time-dep

123 velopmental defects or tooth decay (caries), affect health and quality of life, with associated costs

124 evidence suggests shift work can negatively affect health and wellbeing (increased accidents, fatigu

125 in male mice caused profound HN loss in the affected hemisphere.

126 ve melanocytes from the anagen hair bulbs of affected human scalp remains unclear, oxidative stress s

127 s a vital role in the fish industry and also affects human health from a nutrition point of view.

128 Extreme heat adversely affects human health, productivity, and well-being, with

129 ings demonstrate that environmental geometry affects human spatial memory in a similar manner to rode

130 estinal worms, such as Ascaris lumbricoides, affect hundreds of millions of people in all tropical an

131 at although functional p53 status negatively affects identification of significantly depleted genes,

132 urther demonstrated that Msi1 overexpression affects IEC differentiation in a region-specific manner,

133 within the surface texture, and its role in affecting impalement under ambient conditions through lo

134 Management was affected in 104 of 182 (57%) patients.

135 retinal eccentricity and both are similarly affected in amblyopia.

136 f high-frequency (basal) hair cells was also affected in Ca(V) 1.3(-/-) mice, but to a much lesser ex

137 The mutants were also affected in development as they produced smaller sporang

138 the global total remaining extent of LPE was affected in Florida alone.

139 I trimers and of the monomeric subunits were affected in the phosphatase mutants.

140 insertional Chlamydomonas reinhardtii mutant affected in theVTC2 gene encoding GDP-l-Gal phosphorylas

141 is not clear which specific WM processes are affected in this condition.

142 shape these social environments and in turn, affect individuals' fitness.

143 In both the affected individuals and their asymptomatic carrier pare

144 ant phenotype-SCD occurred in 30 (53%) of 57 affected individuals at a median age of 22.5 years.

145 All affected individuals presented optic atrophy, associated

146 of three fibroblast cell lines derived from affected individuals.

147 This adversely affects individuals of African or Middle Eastern ancestr

148 s, NO is generated in pollen tubes (PTs) and affects intracellular responses through the modulation o

149 e first evaluate the environmental pressures affecting invertebrate communities in two ecoregions (no

150 Immobilizing PBP did not affect its P(i) affinity.

151 is negative regulator of cat-3 expression by affecting its chromatin structure.

152 Studies in vitro and in affected joints demonstrated that A2AR ligation increase

153 and precipitation associated with storms can affect lakes via short-term runoff events from watershed

154 ifically regulates Mac-1, but not LFA-1, and affects leukocyte recruitment by controlling postadhesio

155 inally, treatments that alter nitrate supply affect levels of hypoxic metabolites, nectar volume and

156 cteristics, including section thickness, may affect linear bone measurements of periodontal intrabony

157 Results suggest that although soil structure affects local hydrologic response, its implications on g

158 overall complications, after MIE negatively affect long-term survival of esophageal cancer patients.

159 ndicating that the intracellular environment affects LOV photoreceptor mechanisms in general.

160 proteins (the bulk of cell proteins) without affecting lysosomal proteolysis.

161 lymerase and SIRT1 activities, respectively, affecting many associated biological pathways.

162 he coastal zone, which have the potential to affect marine biodiversity and fisheries.

163 nosensitive channel nanopockets are known to affect mechanical gating and may be linked to large vari

164 r (PCa) is one of the most common cancers to affect men worldwide.

165 Multiple pathogens affect mitochondria dynamics and functions to influence

166 in middle-aged, obese, insulin-resistant men affects mitochondrial respiration, content and morpholog

167 ative evidence on how policies in one region affect mobility and social distancing in other regions a

168 crucial part of critical care that directly affects morbidity and mortality.

169 Much less is known about the trends affecting most invertebrates and other neglected taxa, a

170 Moreover, ALKBH5 affects mRNA stability of receptor tyrosine kinase AXL i

171 Polyphenols affected multiple commensal bacterial groups and showed

172 responses to environmental nitrogen supply, affecting multiple gene regulatory processes including g

173 increased footwear bending stiffness did not affect muscle activity (all seven measured leg muscles (

174 t also revealed that the head domain glycans affect N1 stability more than N2, suggesting N2 is more

175 NR supplementation does not affect NAD metabolite concentrations in skeletal muscle.

176 Antimicrobial resistant (AMR) microorganisms affect nearly 2 million people a year in the United Stat

177 Differential AQP-1 levels affect neural crest cell speed and direction, as well as

178 te interactions represent a delicate balance affecting neural cell functions in health and disease.

179 uromodulation that uses mechanical energy to affect neuronal excitability.

180 patients carries spliceosomal mutations that affect non-hotspot residues, whose potential functional

181 great interest because of genetic variation affecting normal pigmentation variation in humans.

182 Prostate cancer affects one in every nine men in the USA and is the seco

183 Selenium (Se) deficiency and toxicity affect over a billion people worldwide.

184 , changes in HO-1 expression can potentially affect P450 function and, conversely, changes in P450 ex

185 trait impulsivity and acute stress exposure affect participants' choice behavior and decision speed

186 ity in the general population also seemed to affect patients with IEI, including more younger patient

187 onavirus disease 2019 (COVID-19) in severely affected patients includes atypical pneumonia characteri

188 nges and the strength of purifying selection affect patterns of variation at "neutral" sites near fun

189 The disorder affects people of all ages and ethnicities, has a substa

190 ted how altering the actomyosin cytoskeleton affects phagocytic behavior.

191 k TCR stimulation but does not significantly affect phosphorylation of Zap70 (zeta chain of T cell re

192 ficking to probe how various processes might affect polarity site movement.

193 s a neglected tropical disease predominately affecting poor and marginalized populations.

194 dividuals who are less than 50 years of age, affecting probably no more than 1 in 1,000 such infected

195 to provide convergent validation of induced affect processing in the dimension of affective valence.

196 The importance of affect processing to human behavior has long driven rese

197 and clinical differences, EE more frequently affects prosthetic valves and less frequently pacemakers

198 the effect of blanching which can profoundly affect protein composition and introduce protein-primary

199 provide evidence that this modification can affect protein function.

200 nic matter derived from plants (i.e. litter) affect rates of decomposition.

201 one intuitive hypothesis is that pollinators affect rates of plant diversification through their effe

202 and with increased binding to pathologically affected regions in tauopathies and TDP-43-related disea

203 Artifact affects reliability solely in the quadrant in which it o

204 i returned to baseline levels while positive affect remained elevated, and trait anxiety was reduced.

205 ther, we investigated the complex mechanisms affecting reproductive success in an aerial insectivore,

206 ated with decreased risk; these factors also affect risk for CRC onset after age 50.

207 hanges over time and whether such transition affects risks of subtypes of CVD in Chinese adults.

208 adation will thus provide a general route to affect RNA biology.

209 own that single nucleotide polymorphisms can affect RNA secondary structure, and here we show that si

210 how that single nucleotide polymorphisms can affect RNA-protein interactions from outside binding mot

211 regression to evaluate how WIC authorization affected sales of WIC-eligible foods in 8 DVS pilot stor

212 accumulation of beta-1,4-galactan negatively affects salt tolerance.

213 Further, down-regulation of AtPAM16L affected seed germination, even in the presence of its s

214 agulants beginning in 2010 has significantly affected selection of anticoagulants for patients with V

215 isease virus (FMDV) leader proteinase (Lpro) affects several pathways of the host innate immune respo

216 us and reproductive systems disease in three affected siblings of a consanguineous family.

217 were observed between TA-LG co-contraction (affected side, r = 0.557, p = 0.020; contralateral side,

218 We investigated how large herbivore grazing affects soil micro-food webs (microbes and nematodes) an

219 Storage temperature affected stability of anthocyanins, but had minor effect

220 concerning the disparity in outcomes should affect standard specialist practice and the information

221 ve affective and amygdala response to facial affect stimuli returned to baseline levels while positiv

222 Affected subjects exhibit signs of severe neurological d

223 ral to suppressing aggregation, but how they affect substrate conformations remains poorly understood

224 The mutation did not affect surface expression and ligand binding but changed

225 during postnatal day (P) 14-28 period would affect synapse formation and maturation in the developin

226 nd plants in late Paleozoic, would certainly affect terrestrial P input into the ocean, which in turn

227 Adverse events from these agents might affect the ability of patients to tolerate treatment ove

228 ent or decrease resource availability) might affect the abundance and movement rates of animals follo

229 tive responses to ecological uncertainty may affect the dynamics of interspecific interactions and sh

230 By contrast, low pH did not affect the formation of membrane-anchored TNFR1-containi

231 ions in colorectal epithelial cells but also affect the gut microbiota and host immunity.

232 regulation of HSC survival and migration and affect the immune microenvironment, especially macrophag

233 the maintenance of regulatory networks that affect the intricacy of the organism.

234 Elevated pCO(2) was reported to affect the kinetics and thermodynamics of biochemical co

235 Our results indicate that mutations can affect the length in distinct ways.

236 s an ice nucleating particle (INP), BC could affect the lifetime, albedo, and radiative properties of

237 d in the MPO dimerisation zone, was found to affect the local glycan processing, thereby providing a

238 Application of up to 3 mM tricine does not affect the murine b-wave in both genotypes, most likely

239 ntal health problems for nurses and may also affect the nursing care quality for patients.

240 ype of glycosyl donor and acceptor used, can affect the outcome of glycosylation reactions.

241 ics, epigenetics, environment, and nutrition affect the physiological activities of adipose tissues a

242 ular gas outflow is not negligible and could affect the rate of star formation in the central regions

243 cal modifications on fungal oxyluciferin can affect the relative stability of the conformers.

244 tionally, we found that callosotomy does not affect the relative tendency of each hemisphere at gener

245 rovide evidence that global ocean change can affect the resilience of corals to environmental stresso

246 wing season lengths and timings, which would affect the seasonal cycle of atmospheric radiocarbon con

247 How these two forcings affect the seasonal intensity and characteristics of mon

248 tion that are often severe and predominantly affect the spinal cord and optic nerve.

249 set of environmental and physical variables affect the stability of these communities.

250 The local lipid environment is known to affect the structure, stability and intercellular channe

251 ironmental pollutants are known to adversely affect the thyroid hormone system, and major gaps have b

252 nent of Purkinje cell responses, but did not affect the tilt component.

253 ention of TRAF6 expression in melanoma cells affected the activation of CAFs.

254 is approach to examine how a fungal pathogen affected the assembly processes structuring the amphibia

255 changes in grain crystallinity These changes affected the eGI, increasing it for 'KDML105', and lower

256 ot cause maternal anemia but still adversely affected the embryo, causing anemia, tissue iron deficie

257 ne of these isolates carried a mutation that affected the gene encoding the carbon storage regulator

258 arrier proteins revealed that heme primarily affected the tight junction proteins zona occludens-1, c

259 was used to uncover a frame-shift insertion affecting the alpha-L-iduronidase (IDUA) gene (c.19_20in

260 These bases include a common pathology affecting the ascending auditory pathway and multimodal

261 the identification of the factors adversely affecting the capacity to develop oral tolerance to food

262 ause a range of largely syndromic conditions affecting the competency of the basement membranes to wh

263 ry outcome measures were confounding factors affecting the detection of change on macular OCT images.

264 levels of occludin protein and mRNA without affecting the expression of other transmembrane TJ prote

265 udy, we represent a collection of properties affecting the fitness at a given location using a color.

266 ing and stimulus-evoked fluctuations without affecting the integrity of the network.

267 and gross aberrations in myelin organization affecting the nodes of Ranvier, the Schmidt-Lanterman in

268 ta (AI) is a collection of genetic disorders affecting the quality and/or quantity of tooth enamel.

269 e and P species as well as Fe and S species, affecting the solubility and bioavailability of each oth

270 opposite unilateral mechanical perturbations affecting the step length over multiple gait cycles.

271 cus on ecological change as a primary factor affecting the trade-off between male mating and parentin

272 ential mechanisms by which the immune system affects the central nervous system after surgical trauma

273 Thus, the digestion affects the compounds content in both encapsulated and u

274 sts that MCDD induced steatohepatitis barely affects the core clock mechanism but leads to a reprogra

275 othesis" holds that rising income inequality affects the distribution of a wide range of social and e

276 eer wort in terms of amino acid (AA) content affects the final product quality, once it is related to

277 longest, OADH-preferring, phosphonate mostly affects the glutarate level.

278 was replaced by arginine at aminoacid 542), affects the location of the protein as we show in bioche

279 hypothesized that maternal H. pylori status affects the maternal intestinal microbiota of both mothe

280 e data where available, to consider how size affects the primary components of viral fitness.

281 ogy of Fallot, a serious heart valve defect, affects the substrate selectivity of ADAM17 toward Hepar

282 Once affected, the trees are destroyed within a few months, r

283 Treg compartment; however, how such effects affect their disease outcome and long-term health remain

284 ver, little is known about how HIV-1 latency affects their function.

285 Cdc42EP5 affects these functions through SEPT9-dependent F-actin

286 em to evade circulating antibodies and might affect tissue tropism.

287 ssion changes precede disease; and (iii) The affected tissue is a homogeneous single cell monolayer,

288 udying how RNA triggers disease because: (i) Affected tissue is routinely removed during surgery; (ii

289 ot to alter overall expression levels of the affected transcripts but rather the protein-coding regio

290 base equivalents, they could not appreciably affect transport rates of NBCe1 or other transporters ca

291 niques or bulk crystal growth, detrimentally affecting uniformity, scalability, or Curie temperature.

292 Urological obstructive complications (UOC) affect up to 15% of kidney transplants (KTX).

293 entation of NOTCH3 protein in pathologically affected vessels of human CADASIL-affected brains.

294 gh a bile acid-pDC-IFN signaling axis, which affects viremia, dissemination, and potentially transmis

295 olybasic cleavage site in SARS-CoV-2 did not affect virus replication in Vero or Vero-E6 cells.

296 tion of SARS-CoV-2 with this structural loop affecting virus stability and transmission.

297 nd polyhydroxy-fatty acids were specifically affected, while the reduction of epicuticular waxes was

298 the Cre/loxP and Tet-On/Tet-Off systems can affect whole-organism physiology and function due to off

299 This is predicted to affect wild organisms, particularly because of the centr

300 (2) located in nonfrigid zones has been salt-affected with a frequency of reoccurrence in at least th