ライフサイエンスコーパス: aggravate

1 es of OA in the OPOA group were considerably aggravated.

2 aploid A. arenosa and diploid A. lyrata were aggravated.

3 intensity, shape, and position result, which aggravate a correct interpretation of the spectra.

4 pathic pneumonia syndrome-like phenotype and aggravated acute graft-versus-host disease.

5 that TTP in IECs targets Nos2 expression and aggravates acute colitis.

6 horylation by SRPK2 plays a critical role in aggravating AD pathogenesis.

7 Circadian disruption aggravates age-related decline and mortality.

8 activation of each PGD2 receptor resulted in aggravated airway neutrophilia, tissue myeloperoxidase a

9 Global inactivation of CES1 aggravated alcohol- or MCD diet-induced liver inflammati

10 icIL-1Ra1 deficiency aggravated Aldara-induced skin inflammation, as demonstr

11 eption protected WT progeny from allergy, it aggravated allergic airway inflammation in B cell-defici

12 Lastly, inhibition of BTLA by anti-BTLA mAb aggravates alpha-GalCer-induced hepatic injury in CD160(

13 d mitochondrial protein import significantly aggravates alpha-synuclein seeding.

14 current therapeutics against PMO prevent the aggravated alveolar bone loss of periodontitis in estrog

15 -Blockers and ACE inhibitors synergistically aggravate anaphylaxis at least partly by decreasing the

16 Importantly, bestatin does not aggravate anaphylaxis in CD13-deficient mice.

17 reg cells toward a pathogenic phenotype that aggravates and perpetuates disease.

18 ation in COVID-19 patients with diabetes via aggravating Ang-II-dependent pathways and partly driving

19 Infiltrating monocyte-derived macrophages aggravate APAP hepatotoxicity, and the pharmacological i

20 ted that miR-802 overexpression in OLP could aggravate apoptosis of oral keratinocytes by targeting B

21 IL-1R2 deficiency aggravated arthritis severity and increased mRNA levels

22 Moreover, GAP43 knockdown aggravated astrogliosis-induced microglial activation an

23 ls (MCs) are potent innate immune cells that aggravate atherosclerosis through the release of proinfl

24 with KLF2-deficient DCs into Ldlr(-/-) mice aggravated atherosclerosis compared with control mice, m

25 atory T cells is the most important cause of aggravated atherosclerosis in ApoE(-/-)MHCII(-/-) mice.

26 r elevated non-transferrin bound iron (NTBI) aggravates atherosclerosis in mice by driving vascular d

27 suspected mechanism by which sIgM deficiency aggravates atherosclerosis.

28 tains disruption of monocyte homeostasis and aggravates atherosclerosis.

29 a fall in HRV in Ossabaw mini-pigs, implying aggravated autonomic imbalance.

30 to efflux cholesterol without significantly aggravating autophagy defects.

31 ed eosinophil-directed migration in vivo and aggravated both AHR and eosinophil influx into the airwa

32 owth hormone (GH) are elevated in T1D, which aggravates both hyperglycemia and dyslipidemia.

33 This evolved into type III by aggravating both mechanical substrates.

34 netic (beclin siRNA) inhibition of autophagy aggravated BPA neurotoxicity.

35 n injury or cerebral ischemia, significantly aggravates brain damage.

36 exhibits enhanced coupling fidelity, further aggravated by a reduction in beta-adrenergic sensitivity

37 The progression of diabetes in males is aggravated by a selective loss of beta-cell mass, while

38 h greater arterial stiffness and was further aggravated by an unfavourable metabolic profile.

39 coagulation parameters and platelets and is aggravated by anticoagulants.

40 Infection with influenza can be aggravated by bacterial co-infections, which often resul

41 y removal of negative supercoils and further aggravated by expression of mutant Top1.

42 The data showed that defense responses were aggravated by gene networks involved in hypersensitive r

43 eaks and cohesion defects which are strongly aggravated by inactivation of DDX11 but not FANCJ.

44 nsport in China, and accident injury risk is aggravated by inadequate emergency response systems and

45 spread of antibiotic-resistant bacteria are aggravated by incorrect prescription and use of antibiot

46 ain in the right hip and right leg which was aggravated by limb movement.

47 D) is characterized by a skin barrier defect aggravated by mechanical injury inflicted by scratching,

48 efects caused by the sobir1/evr mutation are aggravated by mutating ER, indicating that SOBIR1/EVR an

49 ortality in patients with CKD and is further aggravated by peritoneal dialysis (PD).

50 These degenerative changes are further aggravated by proinflammatory cytokines including IL-1be

51 severe skin fragility and nonhealing wounds aggravated by scarring and fibrosis.

52 holestatic potential of certain drugs may be aggravated by simultaneous inhibition of BSEP and MDR3.

53 n because of progressive muscle degeneration aggravated by sterile inflammation.

54 er, whether these behaviors are mitigated or aggravated by surgery.

55 inhibited by intracellular Ca(2+) chelation, aggravated by thapsigargin, and unaffected by removal of

56 the health care system, a condition that is aggravated by the development of secondary conditions su

57 problem was low TPR, which would be further aggravated by the issues of nonlinearity and nuisance va

58 Concerns posed by arenavirus infections are aggravated by the lack of U.S. Food and Drug Administrat

59 e extent to which inflammatory responses are aggravated by Treg depletion was significantly greater d

60 res are pharmacologically controlled and are aggravated by valproic acid monotherapy.

61 of chronic myocardial edema and inflammation-aggravating cardiac fibrosis and dysfunction.

62 factor (erythroid-derived-2)-like 2 (Nrf2), aggravates cardiotoxin (CTX)-induced tibialis anterior (

63 bers, which did not suffice to significantly aggravate cGN.

64 colitis upon transfer to Itch(+/+) mice but aggravated chemically induced colitis.

65 citatory/inhibitory balance in Orai1 KO mice aggravates chemoconvulsant-mediated seizures.

66 Fats and sugars can aggravate chronic inflammation via effects on intestinal

67 reas IND-treated MDSCs differentiated in TME aggravated clinical symptoms and delayed resolution of t

68 ced viral pathogenicity in dogs, as shown by aggravated clinical symptoms and histopathological chang

69 CGRP pathway blockers might thus aggravate coincidental cerebral ischemic events.

70 e reveal that IEC-specific depletion of Tyk2 aggravates colitis.

71 ific ablation of CD83 expression resulted in aggravated contact hypersensitivity reaction accompanied

72 an overwhelming TH1 immune response, with an aggravated course of the nephritis that was reversible o

73 ls and the induction of TNFalpha, ultimately aggravating Crohn's disease in the AGLCD patient, which

74 S100A8 and S100A9 aggravate CVB3-induced myocarditis and might serve as th

75 ximately 92 in cystic kidneys, which in turn aggravates cyst growth by inhibiting oxidative phosphory

76 nal studies revealed that knockdown of SKAP2 aggravated cytokine-induced apoptosis in INS-1E cells an

77 Helium, injected from plasma, aggravates damage by increasing defect retention.

78 ates neo-antigens favoring autoimmunity, and aggravates damage in ischemia/reperfusion injury.

79 Moreover, the IGF2BP1 deletion aggravated dextran sodium sulfate-induced colitis.

80 cADORA(1) and pADORA(1) signaling hinder and aggravate DIO, respectively.

81 cy could contribute to development of IBD or aggravate disease activity.

82 ncidence of spontaneous CNS autoimmunity and aggravated disease course, especially in the later stage

83 XBP1 or inducible expression of ATF6 in mice aggravates DN.

84 tions, the Li-dendrite growth can be further aggravated due to bending-induced local plastic deformat

85 larly in patients where drug toxicity can be aggravated due to impaired hepatic function.

86 Therapeutic VAS can rescue VAD-aggravated eAD.

87 ork, we demonstrate that hAPP overexpression aggravates EC-Tau aggregation and accelerates pathologic

88 ed that several traits exhibited a gradually aggravating effect as plants were exposed to combined st

89 esynaptic in vivo knockout of beta-neurexins aggravated endocannabinoid-mediated inhibition of synapt

90 Aggravated endothelial injury and impaired endothelial r

91 t of persistent asthma requires avoidance of aggravating environmental factors, use of short-acting b

92 cesses, we determined whether hyperammonemia aggravates ethanol-induced muscle loss.

93 mong the mediators of these effects, miR-217 aggravates ethanol-induced steatosis in hepatocytes.

94 sing CO2 concentrations has the potential to aggravate eutrophication in Taihu Lake where high nutrie

95 ion, disruption of the circadian clock is an aggravating factor associated with a range of human infl

96 of the failing atrium as a primary cause or aggravating factor of the symptoms in many of our patien

97 cancer cell-intrinsic RUNX3 inactivation as aggravating factors for genomic instability.Significance

98 rs and 2 weeks, non-eye pain intensity, QoL, aggravating factors, and associated factors) confirming

99 and interference with quality of life (QoL), aggravating factors, associated factors, associated non-

100 only cause elicited, and explores potential aggravating factors.

101 and the signaling pathways that initiate and aggravate fibrosis in CTS remain unknown.

102 4a) (Trp53(-/-)Cdkn2a(-/-) mice) resulted in aggravated fibrosis after transverse aortic constriction

103 deletion or pharmacologic inhibition of MIF aggravated fibrosis and inflammation, whereas treatment

104 ation and inflammatory T cell responses were aggravated following Treg depletion, regardless of the t

105 eased susceptibility to severe CP, which was aggravated further when combined with smoking.

106 MyD88 deficiency results in accelerated and aggravated gastric pathology induced by Helicobacter thr

107 o its role in intestinal colitis, host NLRP6 aggravated gastrointestinal GVHD.

108 gulation, these results support the value of aggravating genomic instability in cancer cells to enabl

109 The aggravating genotypes were associated with high IL22RA2

110 ARALAR deficiency did not aggravate glutamate-induced neuronal death in vitro, alt

111 n-canonical NF-kappaB signaling was shown to aggravate H. pylori-induced gastric inflammation via act

112 it occurs in several parts of the world, may aggravate harmful effects of ROS-inducing stressors such

113 ert's Syndrome (GS; UGT1A1*28 polymorphism), aggravated health effects have been determined.

114 uring obesity and NAFLD has the potential to aggravate hepatic mitochondrial dysfunction.

115 eviously shown to up-regulate SERPINA1, thus aggravating hepatic accumulation of ATZ.

116 ion of TREM2 was found to be responsible for aggravated hepatitis, indicating a novel role for TREM2

117 of hepatic ChREBP induction in GSD 1a liver aggravates hepatomegaly because of further accumulation

118 Our results indicate that T2DM aggravates HF after MI through defective mitophagy, asso

119 liver lipid transport and ATP synthesis, and aggravating high-fat diet (HFD)-induced NAFLD.

120 responsiveness compromises tissue perfusion, aggravates hypertension, and sets the stage for later pe

121 h defective myogenic vasoconstriction showed aggravated hypotension in response to endotoxin.

122 t NF-kappaB inactivation in oligodendrocytes aggravated IFN-gamma-induced remyelinating oligodendrocy

123 that gp96 released from necrotic hepatocytes aggravates immune hyperactivation and promotes liver dam

124 hippocampal neurons of aged humans, which is aggravated in AD patients.

125 itic spine phenotype of Fmr1(-/y) cortex was aggravated in Fmr1(-/y); Cyfip2(+/-) double-mutant mice.

126 impairment of glucose tolerance were further aggravated in KO mice.

127 TNF-induced albuminuria was aggravated in mice with podocyte-specific ABCA1 deficien

128 begin during puberty and are generally more aggravated in the knockout females.

129 NMJ deficits are aggravated in these mice when compared to single FE65- a

130 Scale formation and acanthosis were aggravated, in correlation with increased IL-17A and IL-

131 Finally, CHK2(-/-) mice display aggravated infarct phenotypes and reduced Beclin 1 p-Ser

132 pathologies in patients with diabetes might aggravate infection course.

133 in-angiotensin system, which correlates with aggravated inflammation and more lung injury.

134 , we report that the mechanism by which this aggravated inflammation arises is through the inhibition

135 Anti-CD3 aggravated inflammation in the small intestines of Slamf

136 ells to provide a feed-forward mechanism for aggravated inflammation.

137 the first time, these data show that TREM-1 aggravates inflammation in ALI by activating NLRP3 infla

138 influx or by enhancing cytokine production, aggravating inflammation and tissue injury.

139 e during coinfection was not associated with aggravated inflammatory cytokine response or cell infilt

140 ice, compared with wild-type mice, exhibited aggravated injury and an impaired transition of renal ma

141 activation further decreased cell viability, aggravated intracellular LDH release, intracellular Ca(2

142 oxidation of oxygen at highly charged states aggravates irreversible structure changes and deteriorat

143 ss nearby vascular structures, which further aggravates ischemia by reducing local microcirculatory f

144 A strong Th17 inflammatory response aggravates ischemia reperfusion-induced (IR-induced) acu

145 When Ager was deleted, hyperglycemia did not aggravate ischemic brain damage any longer.

146 energy substrate of the brain, hyperglycemia aggravates ischemic brain damage in acute stroke.

147 On the one hand, innate immunity both aggravates ischemic injury and impedes remodeling after

148 in mice inhibited fibroblast activation and aggravated kidney injury and functional decline after IR

149 20 haploinsufficiency in vascular allografts aggravates lesions of TA by exacerbating inflammation, S

150 Liver-specific AMPK knockout aggravated liver damage in mouse NASH models.

151 -) mice exhibited increased inflammation and aggravated liver damage upon viral infection, which was

152 Inhibition of KCa3.1 aggravated liver fibrosis during carbon tetrachloride ch

153 , whereas adoptive transfer of hepatic ILC2s aggravated liver inflammation and tissue damage.

154 Importantly, Areg(-/-) mice showed aggravated liver injury after BDL and ANIT administratio

155 ivation of the innate immune system, further aggravating liver injury.

156 lammatory functions early post-APAP, thereby aggravating liver injury.

157 disruption of iron homeostasis and possibly, aggravated loss of liver functions.

158 IIA expression by bone marrow cells severely aggravated lupus nephritis and accelerated death.

159 Allogeneic animals displayed significant aggravated macroscopic skin alterations compared with na

160 d that changes in the fungal communities can aggravate metabolic diseases.

161 s, and conversely, down-regulation of miR-21 aggravated metformin's action and revealed significant p

162 ther no significant (ramipril) or a modestly aggravating (metoprolol) effect, their combined administ

163 Beclin-1/LC-3 and downregulation of p62, and aggravated mitochondrial dysfunctions and ER stress as s

164 These m.3394T>C mutation-induced alterations aggravated mitochondrial dysfunctions associated with th

165 Thus, mutated YARS2 aggravates mitochondrial dysfunctions associated with th

166 to prolonged deterioration of lung function, aggravated mucus production, peri-vascular, peri-bronchi

167 , including eosinophils and lymphocytes, and aggravated mucus production.

168 Suppression of miR-132 aggravates multiple layers of pathology at the molecular

169 en seen in humans with chronic inflammation, aggravates murine atherosclerosis through programming mo

170 mmunization of myositis-prone mice with FHL1 aggravated muscle weakness and increased mortality, sugg

171 annelopathies associated with cold- and K(+)-aggravated myotonias.

172 s themselves, resulting in either minimal or aggravated neointima formation.

173 Thus, aggravated neuritic dystrophy is a more consistent outco

174 experimental studies suggest that a disease-aggravating neuroinflammatory process is present at prec

175 triggers pro-inflammatory processes that can aggravate neuronal degeneration and functional impairmen

176 thermore, absence of Treg1 cells resulted in aggravated NTN with selectively dysregulated renal and s

177 y, this study demonstrates that osteoporosis aggravates OA symptoms.

178 Cystathionine gamma-lyase deficiency aggravates obesity-related insulin resistance via FoxO1-

179 level necessary for genome-editing, thereby aggravating off-target effects.

180 Silencing of Malat1 also significantly aggravated OGD-induced expression of the proapoptotic fa

181 dothelial cells, we here show that TGF-beta1 aggravates oxidative stress-mediated inflammatory activa

182 forest communities and ozone, which further aggravates ozone pollution.

183 degeneration, nerve injury was significantly aggravated (P = 0.032) after prolonged CI.

184 ain-derived neurotrophic factor ratio, which aggravates p75 neurotrophin receptor-mediated cell death

185 rison of the mutations linked to either cold-aggravated pain or pain insensitivity, we propose a mode

186 -of-function context respectively rescues or aggravates parapineal migration defects without affectin

187 keletal muscle regeneration upon injury, and aggravated pathogenesis of a dystrophin-deficient mouse

188 e lacking both CLN6 and CLN8 did not display aggravated pathology compared with the single deficienci

189 get for the treatment of estrogen deficiency-aggravated periodontal bone loss, and berberine represen

190 effects on bone tissue, and osteoporosis can aggravate periodontitis.

191 ge (p.V1184A) in NaV1.9, which leads to cold-aggravated peripheral pain in humans.

192 n culture further enhances MFGE8 expression, aggravates phagocytosis, and leads to neuronal injury.

193 The aggravated phenotype is mediated by increased T helper t

194 tatins enhanced the canonical Hh-pathway and aggravated PHT and angiogenesis.

195 overexpression of miR-466o-3p inhibited WT1, aggravated podocytes injury and deteriorated proteinuria

196 ebellar organotypic cultured slices markedly aggravated prion-induced neurotoxicity.

197 r, whether circulating IGF-1 levels directly aggravate prostate cancer remains elusive.

198 or shortage can increase amyloidogenesis and aggravate protein aggregation disorders.

199 psoriatic skin, and its deletion results in aggravated psoriasis-like skin symptoms following stimul

200 KD in BDL model, beta-catenin KD in Mdr2 KO aggravated rather than alleviated injury by interfering

201 eover, Ackr2 deficiency caused substantially aggravated renal fibrosis in Ackr2(-/-) kidneys 5 weeks

202 2alpha at the beginning of CKD significantly aggravated renal fibrosis, whereas it did not lead to re

203 Glucose metabolism disorders may aggravate respiratory inflammation following exposure to

204 e international rice trade and significantly aggravated rice-derived exposure in Africa (62%), Centra

205 ologic differences, suggesting a potentially aggravating role of LRT in patients with poor tumor biol

206 Moreover, ACE2 deficiency aggravated RSV-associated disease pathogenesis, mainly b

207 S1 overexpressors, which correlated with the aggravated salt hypersensitivity.

208 ctan regulated by the BPC1/BPC2-GALS1 module aggravates salt sensitivity in Arabidopsis thaliana.

209 Such focal brain inflammation aggravates secondary brain injury by exacerbating blood-

210 EGF rescued mice from IDO1 inhibition-driven aggravated shigellosis by restoring the cytokine balance

211 s in patients with cardiogenic shock and may aggravate shock severity and organ failure.

212 Immensely aggravated situation of COVID-19 has pushed the scientif

213 Smoking aggravates skin necrosis as a complication of random-pat

214 ich has no clear therapeutic value and might aggravate some of the adverse effects associated with et

215 and elevated soluble brain Abeta, leading to aggravated spatial learning and memory deficits, thus em

216 3 enzyme is inactivated (Wwp2-C838A) exhibit aggravated spontaneous and surgically induced osteoarthr

217 is loss of chemoconvulsant inhibition likely aggravates status epilepticus in Orai1 KO mice.

218 e on their involvement in neuroinflammation, aggravating stroke, temporal lobe epilepsy, neuropathic

219 Co-transcriptional R-loops could aggravate such conflicts by creating an additional barri

220 Excess weight did not markedly aggravate such findings.

221 nnel does not cause kidney barrier injury or aggravate such injury under pathologic conditions.

222 phritogenic immune responses in vivo, it may aggravate such responses in clinically relevant situatio

223 The loss of oestrogens further aggravates such changes by leading to a notable drop in

224 fter CD8(+) T-cell depletion did not further aggravate symptoms of EBV infection.

225 ty for increased liver steatosis and develop aggravated systemic insulin resistance in response to hi

226 ly third trimester to an intense and acutely aggravating systemic disorder with an important impact o

227 Individuals carrying the aggravating T allele of rs2227473 produced significantly

228 Aggravated TA in HET versus WT allografts correlated wit

229 asia in HET versus WT allografts, indicating aggravated TA.

230 ir follicle cycling and that its absence may aggravate the clinical manifestations of ABCA12 mutation

231 s is underway, the use of norepinephrine may aggravate the development, extent, and duration of sepsi

232 gh clinical relevance because hemorrhage may aggravate the disease state and increase mortality.

233 oss-react with other flaviviruses, which may aggravate the disease via an antibody-dependent enhancem

234 hat these peptides may directly interact and aggravate the disease.

235 reatment of specific inflammatory cells that aggravate the disease.

236 pending on the HDM extract used, but did not aggravate the eosinophilic airway inflammation or airway

237 ge surface area, however, did not noticeably aggravate the fouling problem.

238 onsume tremendous amounts of energy and thus aggravate the greenhouse effect(1,2).

239 is hypothesized that p,p'-DDE exposure could aggravate the harm of an obesogenic context.

240 emplifies how poor nutritional condition can aggravate the life-history costs of resistance and eleva

241 was to evaluate whether a high-fat diet can aggravate the liver disease caused by ligature-induced p

242 e shows full rescue, but three other rescues aggravate the phenotype.

243 ere, we tested the hypothesis that PNE would aggravate the SLCF-mediated apnea and bradycardia via up

244 r many adults throughout the work week-could aggravate the socio-emotional-cognitive processes contri

245 efective refolding of TDP-43 is predicted to aggravate the TDP-43 proteinopathy.

246 reased calcium transients, which can further aggravate the underlying kidney disease.

247 glucose ingestion increased QT interval and aggravated the cardiac repolarization disturbances in LQ

248 l of AD, localized inhibition of 11beta-HSD1 aggravated the development of AD and increased serum cyt

249 a, Pde1c, or Pde3a but not of Pde1b or Pde3b aggravated the development of PKD and was associated wit

250 Loss of Bmal1 aggravated the inflammatory reaction both in vivo and in

251 eutic IKK2 inhibition during ongoing disease aggravated the nephritogenic immune response and disease

252 t skin disease development, IL-22 deficiency aggravated the PsA-like disease in K23 mice.

253 This has aggravated the risk of contaminating agricultural fields

254 mune hyperactivation, whereas exogenous gp96 aggravated the symptoms of hepatic injury in mice but no

255 International trade aggravates the BC pollution over the HTP glaciers and ma

256 mory deficits, whereas neprilysin deficiency aggravates the behavioral phenotypes.

257 itional loss of beta3 integrins dramatically aggravates the bleedings and severely compromises smooth

258 in landfills without proper recycling, which aggravates the burden of waste disposal in landfill.

259 Thus, preexisting CKD aggravates the cardiac dysfunction caused by sepsis or e

260 However, open syntaxin aggravates the defects of unc-18/Munc18 mutants.

261 These data suggest the A30P mutation aggravates the effect of Snca loss in the SVZ.

262 that connective tissue growth factor (CTGF) aggravates the fibrotic environment and drives cancer in

263 f sphingosine kinase-2 (SphK2) but not SphK1 aggravates the formation of atherosclerotic lesions in m

264 w that high-fat diet-induced steatohepatitis aggravates the inflammation in psoriasiform dermatitis,

265 cNAcylation pharmacologically or genetically aggravates the ischemia-induced brain damage, motor defi

266 A high-fat diet aggravates the liver disease caused by ligature-induced

267 esistance, especially among Candida species, aggravates the problem.

268 xpression is itself an oncogenic lesion that aggravates the tumorigenesis induced by p53 loss.

269 ntiation and survival also contribute to IE, aggravating the anemia in BT.

270 may be required to counteract such effects, aggravating the deleterious effects of sympathetic overs

271 affected the dynamics of wound healing, thus aggravating the evolution of remodeling and function.

272 rbates PC12 cell death at least partially by aggravating the mitochondrial impairment and ER stress a

273 in is invariant regardless of blood glucose, aggravating the potential to cause hypoglycemia.

274 ation altered assemble of complex I, thereby aggravating the respiratory phenotypes associated with m

275 Our results suggest that PNE is capable of aggravating the SLCF-mediated apnea and bradycardia thro

276 of patients with atopic dermatitis (AD) and aggravates their disease.

277 restricted to renal tubular epithelial cells aggravated these effects.

278 the titanium surfaces, i.e., corrosion, that aggravate this inflammatory response.

279 h enucleation alone, and adding chemotherapy aggravated this effect.

280 these abnormalities in skeletal muscle, but aggravated those in the heart also causing cardiac fibro

281 le in hemostasis and arterial thrombosis, it aggravates thrombo-inflammatory diseases such as stroke

282 ir dysregulated production and signaling can aggravate tissue damage during infection, inflammatory d

283 diated pyroptosis and IL-1beta release could aggravate tissue injury.

284 Flow cytometric analysis confirmed that the aggravated tissue injury in Tnfr1(-/-)/Mdr2(-/-) mice st

285 B) p65 phosphorylation, while AAT1 knockdown aggravated TNF-alpha-activated NF-kappaB pathway, which

286 injury and increased immunogenicity, thereby aggravating transplant outcomes.

287 Here we show that H3K4me aggravates TRC-induced replication failure in checkpoint

288 kappaB activation in renal tubular epithelia aggravates tubular injury and exacerbates a maladaptive

289 restriction under normoxia that are further aggravated under hypoxia.

290 P-GFP-LC3 reporter cells, and cell death was aggravated upon inhibition of autophagy.

291 This phenotype was further aggravated upon repeated injections of CTLs.

292 CKD), hyperphosphatemia-induced inflammation aggravates vascular calcification (VC) by increasing vas

293 S1P deficiency aggravated vasoplegia in this model, arguing a vital rol

294 inhibition or deficiency diminished HPV and aggravated ventilation-perfusion mismatch.

295 Thus, excessive or prolonged IFN production aggravates viral infection by impairing lung epithelial

296 acts of HI mostly occur upstream, whereas HI aggravate water scarcity downstream; HI cause water scar

297 e the critical dimensions of water scarcity, aggravating water scarcity for 8.8% (7.4-16.5%) of the g

298 e uncertainty in effort judgments is further aggravated when there is no direct access to the interna

299 These deficits were aggravated with aging.

300 consequence, loss of SEDT2 in the intestine aggravated Wnt/beta-catenin signaling effects, thereby l