ライフサイエンスコーパス: aggregating

1 taining disaccharides were amorphous and non-aggregating.

2 preventing non-membrane-bound monomers from aggregating.

3 nic strength in which the nanoparticles were aggregating.

4 ing protection for other lens proteins super-aggregating.

5 the reaction coordinate show a penchant for aggregating.

6 pe-specific IMPACT regulatory annotations by aggregating 5,345 epigenetic datasets to predict binding

7 Aggregating 500 iterations of the model reveals a high-r

8 By aggregating a set of reads into a compressed index, we f

9 Direct exposure of cultured OPCs to aggregating Abeta triggered cell senescence.

10 ficiently decrease the beta-sheet content of aggregating Abeta1-42.

11 ar dynamics simulations, we show that freely aggregating Abeta40 oligomers in physiological solutions

12 Ocean feedback management, and suggest that aggregating abundance across space provides the fastest

13 After aggregating across CABG episodes in a year to construct

14 test this 'social heuristics hypothesis' by aggregating across every cooperation experiment using ti

15 We observed that aggregating across multiple networks improves performanc

16 phasize the enhanced sensitivity imparted by aggregating across voxels that have mixed and weak selec

17 its lectin and beta-glucosidase binding and aggregating activities.

18 and a significant decrease in SP-D-dependent aggregating activity in the lavage of mice acutely expos

19 linking of SP-D and increased SP-D-dependent aggregating activity in the pneumonia model.

20 native human SP-D shows potent antiviral and aggregating activity, trimeric recombinant neck+CRDs (NC

21 t generated by MPO, caused a similar loss of aggregating activity, which was accompanied by the gener

22 -halide system caused loss of SP-D-dependent aggregating activity.

23 associated alterations in its characteristic aggregating activity.

24 y introducing silver colloid, followed by an aggregating agent into the postcolumn flow of an HPLC sy

25 oof of concept is demonstrated using NaCl as aggregating agent, although other inorganic salts will a

26 such as colloid type, its concentration, and aggregating agent, is poorly understood.

27 the synthesis of Satigrel, an anti-platelet aggregating agent.

28 including the type of nanoparticle, pH, and aggregating agents (salts).

29 f five different colloids with six different aggregating agents, and a wide range of concentrations f

30 hereas HIV-1, RSV, and MLV NCs are effective aggregating agents, HTLV-1 NC, which exhibits poor overa

31 ticles, at a high concentration, without any aggregating agents, which gave highly reproducible SERS

32 en amyloid fibril-forming and amorphous beta-aggregating aggregation-prone regions (APRs) in proteins

33 Two model analytes were chosen for aggregating AgNPs, potassium phosphate for neutralizing

34 Analyses aggregating all 6 wk of posttax time points showed stati

35 mates N2 O emissions at the country scale by aggregating all crops, under the assumption that N2 O em

36 terms of a sequence of static networks, each aggregating all edges and nodes present in a time interv

37 By aggregating all possible inheritance patterns via an exp

38 By aggregating all previously utilized measurement instrume

39 Furthermore, by aggregating all tau(q) values of 28 global financial ind

40 abilized oligomers, added to the solution of aggregating alpha-synuclein, were able to noticeably inh

41 een the production and clearance of the self-aggregating amyloid beta protein (Abeta) in brain region

42 We developed a Web-based/mobile platform for aggregating, analyzing, and disseminating regional antim

43 Non-aggregating and aggregating human red blood cell suspens

44 Office of Portfolio Analysis (OPA) has been aggregating and enhancing citation data that can be shar

45 We provide use cases in which aggregating and mining diverse long-tail data convert nu

46 oil conformation, a structure common to both aggregating and non-aggregating species.

47 ata Exchange (ABIDE)-a grassroots consortium aggregating and openly sharing 1112 existing resting-sta

48 ly at risk of misfolding, collecting damage, aggregating, and causing toxicity and disease.

49 d antagonize their vasoconstrictor, platelet-aggregating, and pain-inducing properties.

50 , we have developed a Web-based platform for aggregating antimicrobial resistance indices to support

51 Tissues of wild fish aggregating around farm cages accumulate a greater numbe

52 oward shorter wavelengths in the presence of aggregating aS both in vitro and in cells.

53 entral to the process of hemostasis, rapidly aggregating at sites of blood vessel injury and acting a

54 solution-phase, capture agent-free method of aggregating Au nanospheres in the presence of five neuro

55 h and shellfish common to the U.S. market by aggregating available data from government monitoring pr

56 pipeline of algorithms, including bootstrap aggregating-based Markov random field, weighted co-expre

57 d free energy reduction for partitioning and aggregating beta-sheet peptides into phospholipid membra

58 se), consistent approaches for assessing and aggregating biodiversity impacts across taxa are needed.

59 where the bacteria adhere and form a robust aggregating biofilm.

60 , and inhibitor peptides of detrimental self-aggregating biological proteins.

61 may be attributable to heterogeneity of MDD, aggregating biologically different subtypes.

62 may be attributable to heterogeneity of MDD, aggregating biologically different subtypes.

63 All three mutants were capable of aggregating, but for two of the strains the resulting fr

64 Aggregating C. elegans locally deplete O(2).

65 arily from mutational recurrence analysis by aggregating clinical samples on a large scale.

66 (1)H NMR resonances of aggregating compounds were sensitive to the presence of

67 ved from various methods is advantageous for aggregating compounds with structurally diversified prop

68 method for finding new alpha-synuclein anti-aggregating compounds.

69 rd, and fourth virial coefficients under non-aggregating conditions at concentrations up to 190mg/ml.

70 Under aggregating conditions in vitro, curcumin inhibited aggr

71 tate of PHF6((*)) is readily populated under aggregating conditions, constituting a defining signatur

72 em that prevents individual Sm proteins from aggregating, contributing to cellular UsnRNP homeostasis

73 degron may serve as an instructive "generic" aggregating control protein for studies of disease-assoc

74 ing for CD28 binding to the same ligands and aggregating CTLA-4 to deliver negative signals.

75 ent and interpretation of clinical trials by aggregating data across histologically diverse malignanc

76 lected via EHRs will continuously aggregate; aggregating data enhanced with real-time analytics can p

77 allacy analogous to Simpson's paradox (where aggregating data obscures causal relationships).

78 large quantitative brain imaging consortium, aggregating data to investigate patterns of neuroimaging

79 dementia (FTD) and lead to the production of aggregating dipeptide repeat proteins (DPRs) via repeat

80 toxicity or through the production of toxic aggregating dipeptide repeat proteins.

81 By exploiting the zwitterionic nature of the aggregating discoid dimers, a reversible pH switch was r

82 centration profiles from exponential for non-aggregating dispersions to non-monotonic for aggregating

83 aggregating dispersions to non-monotonic for aggregating dispersions.

84 was created as a centralized gene portal for aggregating distributed gene annotation resources, empha

85 chanism that is sensitive to the cholesterol-aggregating drug nystatin, and is independent of AP-2 cl

86 f the PMCA system as an alpha-synuclein anti-aggregating drug screening assay a panel of 10 drugs was

87 prevents desiccation-sensitive enzymes from aggregating during drying, whereas its counterpart does

88 Positive affect was indexed by aggregating ecological momentary assessments of positive

89 ped a polygenic risk score (PRS) for DILI by aggregating effects of numerous genome-wide loci identif

90 ncounter rate between (equal volume) spheres aggregating either by differential settling or due to tu

91 ng nonemotional cognitive tasks and analyses aggregating emotional and nonemotional tasks showed sign

92 olled polymerization of methacrylates by the aggregating enolate 2, the methacrylate polymerization b

93 se, and improve interpretation and power, by aggregating expression data to the pathway level.

94 We have shown that a beta-glucosidase-aggregating factor (BGAF) is responsible for the "null"

95 th a chimeric lectin called beta-glucosidase aggregating factor (BGAF), resulting in high molecular w

96 lar to the maize (Zea mays) beta-glucosidase aggregating factor.

97 s an extracellular non-sequence-specific RNA-aggregating factor.

98 tend to smooth its spatial heterogeneity by aggregating factors that increase moisture variability w

99 Co-aggregating FcepsilonRI and FcgammaRII with GE2 1) signi

100 dy-dependent cellular cytotoxicity (ADCC) by aggregating FcgammaRIIIA/CD16, contributing significantl

101 ts of membrane-anchored repeats of the trans-aggregating FM domain that face the lumen of the secreto

102 protected against toxicity resulting from an aggregating form of green fluorescent protein (GFP) in a

103 atB) proteolytically degrades Abeta into non-aggregating fragments but is potently inhibited by cysta

104 reporter, this screen readily distinguishes aggregating from nonaggregating variants of Abeta42.

105 Aggregating gene expression through MCF pathways leads t

106 By aggregating genes into large groups with related behavio

107 her polygenic disorders and provide means of aggregating genes/SNPs for further investigation.

108 are variants and quantitative traits include aggregating genotypes and trait values, referred to as '

109 When aggregating GEP to the longer timescales (daily, monthly

110 d nanogel particles (ANPs) were generated by aggregating GNPs to micron-size, which were then stabili

111 , we establish a hydrodynamic description of aggregating granular gases that exchange charges upon co

112 n the human gastric mucosa and is capable of aggregating H. pylori.

113 ana to identify the appropriate criteria for aggregating health data on small tribes.

114 en amyloid fibril-forming and amorphous beta-aggregating hexapeptides with almost 100 percent accurac

115 Non-aggregating and aggregating human red blood cell suspensions were studie

116 We propose four different options for aggregating impacts across taxa and stressors: equal wei

117 s with AuNPs protects the nanoparticles from aggregating in a high-salt solution.

118 Moreover, the three main proteins aggregating in ALS/FTD, including in sporadic cases, are

119 led that Hsp90 prevents alpha-synuclein from aggregating in an ATP-independent manner and that it for

120 Bacteria cooperated by aggregating in cell clusters of ~10 to 20 um, in which c

121 ery poorly soluble and the B-chain is highly aggregating in nature which, together, makes their posts

122 ocused primarily on single interaction types aggregating in space or time.

123 all metallic clusters and prevents them from aggregating in the absence of capping ligands.

124 In T2D patients IAPP is found aggregating in the extracellular space of the islets of

125 bugs to 'hitch-hike' around the world after aggregating in the laundry bags of travellers.

126 nd suppresses unfolded gp4 from irreversibly aggregating in the Salmonella milieu.

127 Farmed fish and wild fish aggregating in the vicinity of four Mediterranean fish f

128 and S262P, dramatically preventing them from aggregating in, and inhibiting motility of, podocytes, f

129 obabilistic maps of anti-dystonic effects by aggregating individual electrode locations and volumes o

130 Surprisingly, however, we find here that aggregating individual gene expression using canonical m

131 of group discussion, and is not a product of aggregating individual opinions (a "wisdom-of-crowds" ef

132 Aggregating individuals were on average larger, but show

133 approach can produce more robust results by aggregating information across multiple, correlated geno

134 sis was performed at a sub-national level by aggregating information from a variety of sources.

135 predicts molecular interactions by not only aggregating information from direct interactions but als

136 This study demonstrates the concept of aggregating information from multiple single nucleotide

137 latent representations in isolation, without aggregating information from neighboring genes.

138 ed in an individual affinity purification by aggregating information from the entire dataset.

139 women and men with traditional risk factors aggregating into a low-intermediate Framingham risk scor

140 tips and then diffuse on the membrane while aggregating into and fragmenting from clusters, before d

141 ch prevents nodes and linear structures from aggregating into clumps and allows normal ring formation

142 Our approach is to simplify the network by aggregating into groups the nodes that do not contribute

143 erate a biomineralized adhesive material for aggregating into large communities.

144 into the more ordered beta-sheets capable of aggregating into stable fibers.

145 o N(pro) did not inhibit these proteins from aggregating into stress granules.

146 In solution, fullerene association to aggregating iron oxide NPs/clusters greatly enhanced the

147 group technique is a method of eliciting and aggregating judgments in a transparent and structured wa

148 The roles for filaggrin monomers in aggregating keratin filaments, as a component of the cor

149 Aggregating Latino subjects into a single group masks si

150 We unexpectedly discover a new class of aggregating ligands that exhibit negligible interactions

151 ts at large extents is commonly investigated aggregating local site data to coarser grains.

152 Thus, using realistic assumptions when de-aggregating locations based on available data can have a

153 l characteristics of spawning behavior in an aggregating marine fish (Cynoscion othonopterus: Sciaeni

154 esent a new, robust and efficient method for aggregating measurements acquired by an uncalibrated WDE

155 e of shared genetic effects was evaluated by aggregating meta-analyzed univariate results across the

156 tallizable fragment receptors (Ig FcRs), and aggregating microbial pathogens.

157 Possible aggregating modes have also been investigated with poten

158 PA was assessed by aggregating momentary assessments over a single day in 3

159 Positive affect was assessed by aggregating momentary experience samples of happiness ov

160 he protein populating less compact forms and aggregating more readily.

161 We introduce SAMF (Solution-Aggregating Motif Finder), a novel approach for motif di

162 uency </=5%) were analyzed by three types of aggregating motifs defined by gene exons, regulatory reg

163 stSignificant is an open-source platform for aggregating multiple sources of quality metrics as well

164 Nonetheless, all 16 of the most aggregating mutants contain substitutions that reduce ch

165 the dynamics of the wild type (WT) and some aggregating mutants through extensive all atom explicit

166 tend the principle of recurrence analysis by aggregating mutations in homologous positions across set

167 Importantly, as compared to the highly self-aggregating N2200, photovoltaic results show that blendi

168 ts, into a statistical physics framework for aggregating nanoparticles.

169 Hence, aggregating negative controls from multiple AP-MS studie

170 Aggregating neuroimaging results regarding nAChR agonist

171 oci and higher concentrations of potentially aggregating non-native protein species within the cell.

172 We also quantified feeding using aggregating npr-1 mutant worms.

173 SNPs (protective; more controls than cases) aggregating on chromosome 14 with P-values <10(-8).

174 sunset, micronekton ascended from the deep, aggregating on the island's shelf.

175 f the house mouse genome, disproportionately aggregating on the X chromosome.

176 d particles were also found to be capable of aggregating one-dimensionally under an electric field or

177 experiments can be improved significantly by aggregating only frames containing signal, and that this

178 is unknown; however, potential scaffolding, aggregating, or other regulatory proteins found in P bod

179 Over the past decade, over 12 thousand aggregating organic molecules have been identified, pote

180 ty in search strategies may be inadvertently aggregating over different subpopulations that use very

181 semble the whole-tumor expression pattern by aggregating over the subpopulation of tissue specimens s

182 wt peptide, a fragment of tau containing the aggregating paired helical filament (PHF6*).

183 olypeptides (ELPs) promotes the formation of aggregating particles that form a "drug depot" at physio

184 gn and co-expression of HTT171-120Q with non-aggregating pathogenic fl-mHTT recruits fl-mHTT to aggre

185 mpletely prevent fibrillation of a synthetic aggregating peptide, YAQ(12)A; it also shows significant

186 ure of the monomeric state of two species of aggregating peptides (human and cat IAPP) and two specie

187 (human and cat IAPP) and two species of non-aggregating peptides (pig and rat IAPP).

188 We designed synthetic aggregating peptides bearing different aggregation prope

189 This quantitative comparison of aggregating peptides of very different lengths is the ba

190 bril formation and affords solubility to the aggregating peptides through its sulfated structure.

191 ntally validated T-cell autoimmune epitopes, aggregating peptides, amyloidogenic proteins and randoml

192 ispersin-null mutants display a unique hyper-aggregating phenotype, accompanied by collapse of AAF pi

193 CC induced ATP release from aggregating platelets, which increased fibrin formation

194 nking to fibrin and assembly by adherent and aggregating platelets-synergize to result in many-fold e

195 adhesion, without appreciably activating or aggregating platelets.

196 -hairpin H-bonding within betaHP, while also aggregating poorly, is ineffective at inhibiting amyloid

197 ary analyses excluding holiday purchasing or aggregating posttax time periods found reductions in tax

198 It has not been possible to identify the aggregating precursor within lens tissues.

199 By aggregating predictions from all three sources, the AUC

200 isoforms, and achieve function prediction by aggregating predictions to their originating genes.

201 yosin binding subunit of MP at Thr(696), and aggregating Pro(33)-positive platelets exhibited an incr

202 The observed SFG signal changes capture the aggregating process of LL-37 on membrane.

203 that our strategy could be extended to other aggregating-prone proteins.

204 as been shown for other granule cargoes with aggregating properties, the condensing activity of ICA51

205 Mutations in the filament aggregating protein (filaggrin) gene have recently been

206 al/epithelial barrier function (eg, filament-aggregating protein [filaggrin]) versus inflammation (eg

207 these proteins, alpha-synuclein, is a toxic aggregating protein associated with synucleinopathies, i

208 en protein are equivalent but rather that an aggregating protein can form different amyloid structure

209 domain-position interaction 'frequencies' by aggregating protein co-complex structures by domain and

210 rnover may be key defense mechanisms against aggregating protein disorders.

211 's, and Huntington's diseases, although each aggregating protein involved is disease specific.

212 heral metabolism, even in cells in which the aggregating protein is not present.

213 p small-molecule binding sites for a rapidly aggregating protein.

214 the disparate timescales involved, since the aggregating proteins are simultaneously the reactants, p

215 ing evidence points to soluble assemblies of aggregating proteins as a major mediator of neuronal and

216 egation in recent years, many aspects of the aggregating proteins behavior remain unclear because of

217 able to interact with and disaggregate other aggregating proteins that contain prolines.

218 blem, therefore, to choose the states of the aggregating proteins that should be bound by the compoun

219 ol protein for studies of disease-associated aggregating proteins, such as huntingtin, alpha-synuclei

220 ine-rich, heptad-repeat region; a feature of aggregating proteins, within the C-terminal region of DE

221 the toxicity of the overproduced potentially aggregating proteins.

222 In contrast, the large aggregating proteoglycan aggrecan was increased.

223 4 and -5 share the abilities to cleave large aggregating proteoglycans including versican and aggreca

224 the hyalectin (or lectican) family of large, aggregating proteoglycans or the decorin (or small leuci

225 of comparative methods is perversely narrow: aggregating public datasets only produced one phylogenet

226 protocol using FastQC, parsing results, and aggregating quality metrics into an interactive dashboar

227 cted significant association with HbA1c when aggregating rare missense variants in G6PD.

228 ividual variants as well as gene-based tests aggregating rare, predicted functional, and loss of func

229 the ones containing experimentally validated aggregating regions are enriched in hydrophobicity by 10

230 ity (63%) of those containing amorphous beta-aggregating regions bind HLA-DQ.

231 ocyte Antigen (HLA)--types recognized by the aggregating regions containing epitopes.

232 s and (iii) analyzing genes one by one, then aggregating results can lead to information loss.

233 lab-ware, dust and aggregated & dynamically aggregating sample, for example.

234 utralized charges within junction; (2) "self-aggregating sensors"; and (3) sensors incorporating fluo

235 l and helix-hairpin conformations as the non-aggregating sequence, but, in addition, populate a hairp

236 The aggregating sequences, on the other hand, populate the s

237 en biomedical concepts and database records, aggregating sets of identifiers denoting the same biomed

238 Aggregating single networks together resulted in improve

239 annotation (MAGMA), addresses this issue by aggregating single nucleotide polymorphism associations

240 We identified several different aggregating sites from limited proteolysis of harvested

241 An ordered conglomerate of an aggregating small-molecule inhibitor (JNJ525) induces a

242 By combining pre-aggregating solvents for formulating the semiconductor a

243 Aggregating, sorting and summarizing variants and effect

244 single cells and subpopulations of cells by aggregating sparse signal across hundreds or thousands o

245 plan aquatic landscape genomics projects by aggregating spatial and software resources and offering

246 mplicated in human diseases, and many of the aggregating species accelerate amyloid formation and ind

247 the hairpin structure, only observed in the aggregating species, might be linked to the pathological

248 structure common to both aggregating and non-aggregating species.

249 stable molten globules states or amorphously aggregating species.

250 ming of the basophil response to FcepsilonRI aggregating stimuli remains unknown.

251 ee of isohydricity at the ecosystem scale by aggregating studies of individual species.

252 for a duplication block to be constructed by aggregating substrings of other blocks.

253 ril formation in polyglutamine peptides, the aggregating subunit associated with Huntington's disease

254 f-assembly of rotors are generic features of aggregating swimmers and should therefore occur in a var

255 l that involves negative cooperativity in an aggregating system.

256 model involving negative cooperativity in an aggregating system.

257 ur model establishes a link between specific aggregating systems and the physical conditions maximizi

258 ence of increasing proportions of the slowly aggregating tau isoform gradually lowers the concentrati

259 auopathies, as the ratios of fast and slowly aggregating tau isoforms in brain varies substantially i

260 ggest that cells respond to VSV infection by aggregating the antiviral proteins, such as PCBP2 and TI

261 sses challenges encountered by the USPSTF in aggregating the behavioral counseling intervention liter

262 By aggregating the computational power of high performance

263 11 861 psoriasis cases and 28 610 controls, aggregating the dataset through statistical meta-analysi

264 a key condition for collective intelligence: Aggregating the independent judgments of doctors outperf

265 Aggregating the prognostic effects of genetic variants a

266 The results suggest that aggregating the ranks of molecules across docking calcul

267 s, we conduct the first large-scale analysis aggregating the results of 18 circadian transcriptomic s

268 ts for reference, novel ways for scoring and aggregating the results were developed.

269 biological meanings) into a numeric value by aggregating the semantic contributions of their ancestor

270 Aggregating the testing information from each compound a

271 nces might relate to the VMPFC automatically aggregating the values of contextual features, which wou

272 ojecting them across congruent sequences and aggregating their diverse representations are critical t

273 extended the short segments of the reads by aggregating their overlapping reads.

274 ng the model-training to the data-owners and aggregating their results.

275 ferent sRNA prediction methods and optimally aggregating them as potential predictors.

276 e harmonize extracted adverse event terms by aggregating them into higher-level MeSH terms based on t

277 For bacterial data, we show that aggregating these datasets allows a single NMP library t

278 ic models at the single-cell level, and then aggregating these models to give a likelihood that links

279 3), and develop a method to forecast ILI by aggregating these predictions.

280 ils and rodent mast cells is decreased by co-aggregating these receptors to the low affinity IgG rece

281 tting the null model for each study and then aggregating these score statistics across studies.

282 Aggregating three stages, FGFRL1 rs4647940 was the singl

283 temporal changes in the fractal dimension of aggregating TiO(2) and ZnO nanoparticles.

284 ng across the bilayer hydrocarbon region and aggregating to form a pore, whereas in the "toroidal por

285 ovel insight into the switch mechanisms from aggregating to procoagulant platelets.

286 ontent, we identified 5 guiding criteria for aggregating tribal health data: geographic proximity, co

287 Experimentally aggregating tumor cells into clusters induced a >15-fold

288 overishment due to out-of-pocket payments by aggregating up from each country, using a survey for the

289 We estimated global incidence by aggregating up from every country, using a survey for th

290 wise variances and the smoothing methods for aggregating variance information.

291 , demonstrating the in vivo toxicity of this aggregating variant.

292 ariants from sequencing data have focused on aggregating variants in a gene or a genetic region becau

293 ne conformation that would lead normally non-aggregating variants of IAPP to form fibrils under condi

294 We also demonstrate that aggregating variants of the polyQ-containing domain of h

295 Preventing disassembly of the vimentin by aggregating vimentin filaments using beta,beta'-iminodip

296 to increase power in association studies by aggregating weak individual effects.

297 endowed superior biophysical properties (non-aggregating, well-expressed, and heat-refoldable) onto d

298 by stabilizing those crystals and further co-aggregating with melamine.

299 yeast, identifying >170 endogenous proteins aggregating within minutes of heat shock in multiple sub

300 entified significant overlaps between stress aggregating yeast proteins and proteins that aggregate d