ライフサイエンスコーパス: airway obstruction

1 eterminant for initiating RSV-induced distal airway obstruction.

2 ic epithelial cells, leading to acute distal airway obstruction.

3 d produce mucus, an important contributor to airway obstruction.

4 offspring, thereby predisposing to postnatal airway obstruction.

5 these children develop postextubation upper airway obstruction.

6 ografts is attributable to progressive small airway obstruction.

7 nic endobronchial infection, and progressive airway obstruction.

8 circulating granulocytes that caused severe airway obstruction.

9 examine independently both small- and large-airway obstruction.

10 He had mild reversible airway obstruction.

11 wed by eosinophil-dominated inflammation and airway obstruction.

12 nflammation, mucus production and reversible airway obstruction.

13 p asthma, a serious disorder of intermittent airway obstruction.

14 xacerbate the inflammatory process and cause airway obstruction.

15 distal airways in association with clinical airway obstruction.

16 ates in subepithelial fibrosis with variable airway obstruction.

17 tress in the lung and limiting the degree of airway obstruction.

18 airway hyperreactivity (AHR) and reversible airway obstruction.

19 ce, increased pulmonary edema, and extensive airway obstruction.

20 LP and TARC/CCL17 expression correlated with airway obstruction.

21 and LOA (P = 0.0003) scores than those with airway obstruction.

22 tein level and correlated with the degree of airway obstruction.

23 correlated with TARC and MDC expression and airway obstruction.

24 ranging from infrequent recurrence to acute airway obstruction.

25 ses with the progression of malnutrition and airway obstruction.

26 is a hallmark of asthma that contributes to airway obstruction.

27 atients with COPD who do not have reversible airway obstruction.

28 nd quality of life with treatment of central airway obstruction.

29 disruption that occurs in response to upper airway obstruction.

30 ema, abnormal lung compliance, and extensive airway obstruction.

31 nflammatory disease of the lung resulting in airway obstruction.

32 fetal lesions causing extrinsic or intrinsic airway obstruction.

33 ponsiveness (AHR) to contractile stimuli and airway obstruction.

34 r, and extubation failure secondary to upper airway obstruction.

35 to diacetyl and the frequency and extent of airway obstruction.

36 obin concentration, and hypoxemia from upper airway obstruction.

37 d by neuromuscular blockade with and without airway obstruction.

38 a chronic disease of the lung resulting from airway obstruction.

39 mechanically ventilated patients with severe airway obstruction.

40 sation of breathlessness (dyspnea) caused by airway obstruction.

41 l than inspiratory CT for diagnosis of small airway obstruction.

42 48 hrs of extubation in the absence of upper airway obstruction.

43 tic complications had satisfactory relief of airway obstruction.

44 were necessary to achieve adequate relief of airway obstruction.

45 rproduction, a condition that contributes to airway obstruction.

46 malities were identified in all animals with airway obstruction.

47 fects, usually congenital, that cause severe airway obstruction.

48 men 35 to 60 yr of age with mild-to-moderate airway obstruction.

49 that HFO at 15 Hz resulted in greater large airway obstruction.

50 ute to the mechanism by which LVRS palliates airway obstruction.

51 which contributes to bronchoconstriction and airway obstruction.

52 is closely related to both EMT activity and airway obstruction.

53 ssion of miR-218-5p strongly correlated with airway obstruction.

54 s, and the risk of asphyxiation due to upper airway obstruction.

55 lification loop, mucosal IFN expression, and airway obstruction.

56 sociated genes correlates with the degree of airway obstruction.

57 tween 5 and 19 Hz, the indices of peripheral airway obstruction.

58 aracterized by eosinophilic inflammation and airway obstruction.

59 direct effects on mast cell-driven allergic airway obstruction.

60 ay be less sensitive in regard to peripheral airway obstruction.

61 iRNA levels in nasal lavages associated with airway obstruction.

62 ypical symptoms in combination with variable airway obstruction.

63 causes severe lung inflammation, leading to airway obstruction.

64 stration aids resolution of these functional airway obstructions.

65 urgical procedures for the relief of central airway obstructions.

66 ver, only asthma is associated with variable airways obstruction.

67 imilar for patients with concomitant chronic airways obstruction.

68 urces for COPD patients with moderate/severe airways obstruction.

69 the same time that the FEV1 revealed ongoing airways obstruction.

70 rrence of laryngeal lesions with the risk of airways obstruction.

71 reintubation was classified as airway (upper airway obstruction, 11; aspiration/excess pulmonary secr

72 Common reasons for exclusion were upper airway obstruction (13.5%) and cyanotic congenital heart

73 way inflammation 1-2 days after exposure and airway obstruction 2-3 days after exposure.

74 studied 3, 926 smokers with mild-to-moderate airway obstruction (3,818 with analyzable results; mean

75 ontrolled, and with severe exacerbations and airway obstruction (41.3% of patients); and class 4, poo

76 [aOR], 1.93; 95% CI, 1.06-3.55; P = .03) and airway obstruction: 50% of forced expiratory flow (abeta

77 used spirometry as the primary assessment of airway obstruction, a method that may be less sensitive

78 al pulmonary function compared to those with airway obstruction after adjusting for age, race, gender

79 Asthma is characterized by variable airway obstruction, airway hyperresponsiveness, and airw

80 sthma is a complex syndrome characterized by airway obstruction, airway inflammation and airway hyper

81 ether obese asthma patients have more severe airway obstruction and airway hyper-responsiveness and a

82 of the lung, is characterized by reversible airway obstruction and airway hyperresponsiveness (AHR),

83 iated with airway hyperresponsiveness (AHR), airway obstruction and airway remodelling.

84 essive lung disease culminating in permanent airway obstruction and alveolar enlargement.

85 sure to cigarette smoke (CS), which involves airway obstruction and alveolar loss (i.e., emphysema).

86 ronchial asthma is characterized by episodic airway obstruction and associated with wheezing, a bronc

87 sex or by manual/nonmanual work.Conclusions: Airway obstruction and breathlessness are independently

88 lergic asthma is characterized by reversible airway obstruction and bronchial hyperresponsiveness ass

89 inflammatory response that leads to chronic airway obstruction and bronchiectasis.

90 orced vital capacity, a sensitive measure of airway obstruction and bronchodilator response, which me

91 The model differentiates between upper airway obstruction and complications like bronchospasm a

92 way mucus overproduction that contributes to airway obstruction and death.

93 to 1.9 +/- 1.3 cm H2O, leading to increasing airway obstruction and decreasing levels of inspiratory

94 pecimens, was not associated with reversible airway obstruction and did not correlate with the severi

95 Rint was increased in the patient with lower airway obstruction and five of six patients without prim

96 the signature was associated with increased airway obstruction and functional small airways disease

97 cal and physiological predispositions toward airway obstruction and gas exchange abnormalities; inclu

98 They also had the greatest airway obstruction and hyperreactivity compared with the

99 c mice developed clinical disease, including airway obstruction and hyperresponsiveness (AHR), along

100 Airway obstruction and hyperresponsiveness do not change

101 zed anticoagulants will reduce the degree of airway obstruction and improve pulmonary function in she

102 The treatment reduced the degree of airway obstruction and improved pulmonary gas exchange,

103 ulation) are potentially at risk for greater airway obstruction and increased asthma morbidity.

104 ons through the airway epithelium will limit airway obstruction and inflammation and may be therapeut

105 ies have the potential to effectively reduce airway obstruction and inflammation in allergic asthma.

106 hronic respiratory disease, characterized by airway obstruction and inflammation.

107 in acute lung injury due to a combination of airway obstruction and inflammation.

108 ous smoking-related disease characterized by airway obstruction and inflammation.

109 Airway obstruction and injury scores were not different

110 tudy was to examine the relationship between airway obstruction and periodontal disease.

111 tion of some complications, especially upper airway obstruction and possibly immune-mediated anemia a

112 nchiolitis can damage the airways to promote airway obstruction and recurrent wheezing.

113 ncludes preoperative treatment of reversible airway obstruction and respiratory infections, smoking c

114 n activity during sepsis might induce severe airway obstruction and that supplementation with antithr

115 sion in asthmatics with different degrees of airway obstruction and the validity of proposed TMAD-cor

116 sential to understand the pathophysiology of airway obstruction and to identify novel therapeutic tar

117 lometry reactance area indicating peripheral airway obstruction and urinary leukotriene E(4) levels i

118 er increased MUC5AC secretion alone produces airway obstruction and/or inflammation, we generated a m

119 uggest that excessive mucin secretion causes airways obstruction and inflammation.

120 ith parenchymal lung disease; one with lower airway obstruction) and six without primary lung disorde

121 tified genes are also involved in emphysema, airway obstruction, and bronchial inflammation.

122 ssive condition of chronic bronchitis, small airway obstruction, and emphysema that represents a lead

123 ase characterized by airway hyperreactivity, airway obstruction, and histologic inflammation.

124 groups of features: atopic burden, degree of airway obstruction, and history of exacerbation.

125 -linking Ab that prevents lung inflammation, airway obstruction, and hyperreactivity to allergen in a

126 mation and contributes to clinical symptoms, airway obstruction, and mortality.

127 verse correlations with sputum eosinophilia, airway obstruction, and number of hospitalizations in as

128 ong channels included body movement, partial airway obstruction, and obstructed breaths.

129 littermate controls; identified locations of airway obstruction, and quantified regions of bimodal ai

130 , and 1 (6%) each from tension pneumothorax, airway obstruction, and sepsis.

131 ated with increases in lung edema formation, airway obstruction, and vascular endothelial growth fact

132 ystals, airway fibrosis, eotaxin production, airways obstruction, and nonspecific AHR.

133 ty is mostly caused by bronchiectasis, small airways obstruction, and progressive respiratory impairm

134 hy, before and after methacholine, to assess airway obstruction (AO) and airway hyperreactivity (AHR)

135 tion, IFN-gamma:IL-4 mRNA expression ratios, airway obstruction (AO), and airway hyperreactivity (AHR

136 ed with acute morbidity (e.g., pneumonia and airway obstruction [AO]) and long-term complications (e.

137 disorders ranging from altitude sickness to airway obstruction, apnea, and atelectasis.

138 hicle-treated bronchi resulted in late-phase airway obstruction (approximately 120% increase over bas

139 tested the hypotheses that markers of small airway obstruction are associated with (i) increased ast

140 Patients with poor perception of airway obstruction are at risk of delay in seeking medic

141 ng cancer; however, benign causes of central airway obstruction are being seen more frequently as wel

142 Current methods for studying airway obstruction are inadequate in safety, cost, or av

143 t cell metaplasia, mucus hypersecretion, and airway obstruction are integral features of inflammatory

144 e of chronic lung allograft failure is small airway obstruction arising from bronchiolitis obliterans

145 n steroid treatment ethane was correlated to airway obstruction as assessed by the ratio of residual

146 Histopathology revealed pulmonary edema and airway obstruction as the morphologic correlates of the

147 CD4(+) and CD8(+) T cells completely blocked airway obstruction as well as AHR.

148 analysis is the first to suggest that small-airway obstruction, as assessed based on FEF25-75, might

149 n the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg, po) and demons

150 ontrols at 245 days (P = 0.03) and increased airway obstruction at 530 days (P = 0.01).

151 the associations between breathlessness and airway obstruction at baseline and loss of employment in

152 criteria of attacks of wheezing, reversible airway obstruction, atopy, and that increased IgE.

153 Control and COPD subjects with mild airways obstruction (baseline FEV(1) >/= 50% predicted)

154 of pulmonary nitrosative stress (p = 0.002), airway obstruction (bronchi: p = 0.001, bronchioli: p =

155 ood lipid profile is associated with asthma, airway obstruction, bronchial responsiveness, and aeroal

156 posure to POPs appears to be associated with airway obstruction but not allergic sensitization at 20

157 The genotype increased the odds of airway obstruction by 75% within asthmatics only.

158 th aerosolized heparin attenuated late-phase airway obstruction by approximately 50%, inhibited eosin

159 inically similar asthma patients may develop airway obstruction by different mechanisms.

160 s increased in COPD airways, and may promote airway obstruction by enhancing the expression of contra

161 ppears to be a major mechanism through which airway obstruction by spasmogens is avoided.

162 cough by 56% and maximal Penh (a measure of airway obstruction) by 43%, effects that were attenuated

163 e beneficial to most patients and almost all airway obstruction can be relieved expeditiously.

164 ry disease that is characterized by variable airways obstruction caused by acute and chronic bronchia

165 n severe asthma may relate to the peripheral airway obstruction characteristic of this condition.

166 ome 17q21 locus relates to episodes of acute airway obstruction common to both transient wheeze and a

167 We conclude that airway obstruction commonly occurs in patients with Fabr

168 gic agonist bronchodilators to patients with airways obstruction commonly results in transient decrea

169 tion and burn injury, bronchospasm and acute airway obstruction contribute to progressive pulmonary i

170 Whether small-airway obstruction contributes to the long-term evolutio

171 inhaled bronchodilators to partially improve airway obstruction, corticosteroids to decrease the like

172 Greater airway obstruction [decreased forced expiratory volume i

173 (CLD) (HR, 3.09; P = .024) and those without airway obstruction, defined by a ratio of forced expirat

174 e patients with asthma developed significant airway obstruction (deltaFEV1, -27.7 +/- 2.9%; p = 0.000

175 Persistent severe airway obstruction despite massive doses of corticostero

176 tients, the presence, location, and cause of airway obstruction determined at MR imaging were confirm

177 Previously reported markers of small airway obstruction do not appear to be independently ass

178 surements correlate with the degree of upper airway obstruction during sleep and may have a role in t

179 ea (OSA) is characterized by recurrent upper airway obstruction during sleep.

180 include a positive response to albuterol and airway obstruction, factors that could help identify app

181 = 0.47, P = 0.04; AMC: r = 0.45, P = 0.04), airway obstruction (FEV(1): r = 0.68, P = 0.001), and ar

182 owever, positively associated with offspring airway obstruction (FEV1 /FVC < 75%).

183 genes in BECs from children with asthma and airway obstruction (FEV1/forced vital capacity < 0.85 an

184 R-142-3p expression was associated also with airway obstruction (FEV1/forced vital capacity).

185 200 cells/microliter) was 90% in predicting airway obstruction (FEV1/FVC < 0.8).

186 s had severe Brasfield scores (9.0 +/- 3.2), airways obstruction (FEV1 25.6 +/- 5.6% predicted, FEF(2

187 PGA manifests as an uncoupling of airway obstruction from airway inflammation that can be

188 any neuromuscular disorders mechanical upper airway obstruction from oropharyngeal weakness contribut

189 tient received RF ablation for prevention of airway obstruction from progressive diffuse large B-cell

190 We found that abnormal perception of airway obstruction has important clinical implications f

191 Many modalities for central airway obstruction have emerged, including the expanding

192 In mechanically ventilated patients with airway obstruction, helium-oxygen (He-O2) mixtures reduc

193 length of ventilation, postextubation upper airway obstruction, high respiratory effort postextubati

194 disease, lower aPiMax, postextubation upper airway obstruction, higher preextubation positive end-ex

195 Asthma is a chronic lung disease exhibiting airway obstruction, hyperresponsiveness, and inflammatio

196 In asthma, the mechanisms relating airway obstruction, hyperresponsiveness, and inflammatio

197 matrix metalloprotease levels in sputum, and airway obstruction in a cohort of human immunodeficiency

198 Inhaled bitter tastants decreased airway obstruction in a mouse model of asthma.

199 better discrimination between normality and airway obstruction in adults of at least these three eth

200 n important factor contributing to increased airway obstruction in allergen-induced exacerbation of a

201 ed Cl- secretion is essential for preventing airway obstruction in allergic airway disease.

202 Mucous hypersecretion is a major cause of airway obstruction in asthma, chronic obstructive pulmon

203 y of inflammatory diseases, in particular of airway obstruction in asthma.

204 the mucus gel or how this gel contributes to airway obstruction in asthma.

205 nism has implications for the development of airway obstruction in asthma.

206 I could contribute to the pathophysiology of airway obstruction in asthmatic patients.

207 new role for FENO in identifying the site of airway obstruction in asthmatic patients.

208 associated with markers of inflammation and airway obstruction in asthmatic subjects exposed to anti

209 designing novel therapies to reverse MCM and airway obstruction in asthmatics.

210 ometric measurements to identify patterns of airway obstruction in children and define obstruction ph

211 begs the question, Is it possible to reduce airway obstruction in chronic lung disease by inhibiting

212 modeling, which contributes significantly to airway obstruction in chronic obstructive pulmonary dise

213 is common in smokers and is associated with airway obstruction in chronic obstructive pulmonary dise

214 A major mechanism of airway obstruction in COPD is thickening of the small ai

215 ly cause conductive hearing loss in COME and airway obstruction in COPD.

216 t association between periodontal health and airway obstruction in former smokers.

217 The genes HHIP and FAM13A confer a risk for airway obstruction in general that is not driven exclusi

218 ade in the prevention and treatment of upper airway obstruction in infancy and childhood.

219 ssive airway mucin production contributes to airway obstruction in lung diseases such as asthma and c

220 We determined whether upper airway obstruction in normal individuals with intact ref

221 st and safe tool to identify simulated sleep airway obstruction in patients with OSA.

222 Abundant airway mucus contributes to airway obstruction in RSV disease.

223 th conventional tracheal suction, to prevent airway obstruction in sheep with the ETT and trachea ori

224 The role of small airway obstruction in the clinical expression of asthma

225 te this association, PAI-1 may contribute to airway obstruction in the context of chronic asthmatic a

226 n tests revealed air trapping and mild lower airway obstruction in the ECMO group, compared with mean

227 structural component in determining variable airways obstruction in asthma.

228 Airway obstruction, including AHR and airway resistance,

229 nhalation, with increased airway reactivity, airway obstruction, inflammation and emphysema.

230 upational lung disease marked by restrictive airway obstruction, inflammation, and fibrosis.

231 Airway obstruction is a hallmark of allergic asthma and

232 Airway obstruction is a physiologic feature of asthma, a

233 Central airway obstruction is a problem facing all medical and s

234 e observed that IL-15-mediated protection of airway obstruction is associated with induced IFN-gamma-

235 The other main cause of airway obstruction is contraction of airway smooth muscl

236 We conclude that reversible airway obstruction is found in LAM patients with acceler

237 asminogen activator inhibitor-1 (PAI-1) with airway obstruction is modified by asthma status, and whe

238 Even though upper airway obstruction is potentially life-threatening, a se

239 hetic drug-induced respiratory depression or airway obstruction leading to hypoxemia or hypoventilati

240 The putative small airway obstruction markers Sacin , resistance at 5 Hz mi

241 Colonized subjects exhibited more severe airway obstruction (median FEV(1) = 21% predicted versus

242 Although asthma is characterized by variable airways obstruction, most studies of asthma phenotypes a

243 y increases toward areas most susceptible to airway obstruction (nose < bronchi << bronchioles).

244 mpliance (p = 0.005) than control rats, with airway obstruction occurring in an episodic pattern.

245 itulate craniofacial abnormalities and upper airway obstruction of human DS and can serve as an exper

246 stigate the effect of nutritional status and airway obstruction on diaphragm strength.

247 ever therapy only) do not present reversible airway obstruction or airway hyperresponsiveness to indi

248 39% increase in risk of clinically relevant airway obstruction (OR=1.39, CI: 1.01, 1.92, P=.04).

249 association between periodontal disease and airway obstruction, particularly in former smokers.

250 Airway obstruction plays an important role in pulmonary

251 ), and forced expiratory volume in 1 second (airway obstruction, r = 0.7; 95% CI: 0.21, 0.91).

252 y subjects, patients with moderate-to-severe airways obstruction receive an increased dose from ultra

253 PG-CAT treated mice showed amelioration in airway obstruction, reduction in neutrophil elastase and

254 When children developed postextubation upper airway obstruction, reintubation rates were 47.4% for th

255 hese children developed postextubation upper airway obstruction, reintubation rates were greater than

256 values in asthmatic patients as a result of airway obstruction relief occurring at different lung de

257 er bronchodilation, depending on the site of airway obstruction relief.

258 Despite all these advances, upper airway obstruction remains an important source of morbid

259 characterized by impaired lung function and airway obstruction resulting from interactions between m

260 fore defibrillation, removal of foreign-body airway obstruction, resuscitation care for suspected opi

261 t regimen helped to resolve life-threatening airway obstruction secondary to fibrin casts.

262 Airway obstruction secondary to recurring casts improved

263 However, upper airway obstruction secondary to severe bleeding in the f

264 r transplantation in smokers with a range of airway obstruction severity and in a control group with

265 A case-control study of airway obstruction showed that waist circumference was s

266 = 10) and in subjects with varying levels of airway obstruction: smokers (S; n = 10), smokers with sm

267 uamation and mucus hypersecretion leading to airway obstruction, subepithelial fibrosis, airway smoot

268 cumulation of these cells is associated with airway obstruction, suggesting that they may play a sign

269 ients without known CLD and patients without airway obstruction.Supplemental material is available fo

270 Congenital high airway obstruction syndrome (CHAOS) is a rare fetal anom

271 of 24 cases by demonstrating congenital high airway obstruction syndrome, congenital hemochromatosis,

272 es have a clinically significant role in the airway obstruction that characterizes asthma.

273 plays an intimate role in the development of airway obstruction that follows hyperpnea.

274 sleep causing snoring and, in serious cases, airway obstruction that interrupts breathing, a conditio

275 pressures, pulmonary dysfunction, and upper airway obstruction that occur after combined smoke inhal

276 s, but also to prevent recurrent symptoms of airway obstruction that occur in some children for years

277 IL-15 has a potent inhibitory effect on the airway obstruction that occurs in response to environmen

278 e likely caused by relief of an intra-acinar airway obstruction that we propose reflects amplificatio

279 In addition to airway obstruction, the loss of hypoxic pulmonary vasoco

280 ponent in the initiation and perpetuation of airway obstruction, the triggers underlying mucin releas

281 e workers had 3.3 times the expected rate of airway obstruction; those who had never smoked had 10.8

282 logical processes spanning the spectrum from airway obstruction to lung remodeling can lead to multif

283 clinically significant post-extubation upper airway obstruction (UAO) and differentiate subglottic fr

284 ese symptoms and demonstration of reversible airway obstruction using spirometry.

285 s of these regimens on lung injury severity, airway obstruction, ventilation, oxygenation, pulmonary

286 Quantifying underlying small airway obstruction via PRM(fSAD) helps further stratify

287 Airway obstruction was created by inflating a 5-F balloo

288 Airway obstruction was defined as FEV1/FVC ratio <0.7.

289 Airway obstruction was defined as forced expiratory volu

290 rongly associated with wheeze and atopy, and airway obstruction was less reversible, asthma in some c

291 Upper airway obstruction was produced in 12 normal individuals

292 Moderate to severe airway obstruction was seen in 3.6%.

293 Airway obstruction was seen, starting from generation 6

294 Airway obstruction was statistically elevated in MpIL12

295 pacity and to markers for hyperinflation and airway obstruction were found in patients with CF.

296 Two levels of upper airway obstruction were induced in ten dogs by partially

297 Airways obstruction with thick, adherent mucus is a path

298 in elderly patients with severe irreversible airway obstruction, withdrawal of inhaled corticosteroid

299 ociation of the polymorphism with asthma and airway obstruction within asthmatics via multivariate lo

300 in elderly patients with severe irreversible airway obstruction would not lead to a deterioration in