ライフサイエンスコーパス: aldehyde

1 n making an aliphatic alpha,beta-unsaturated aldehyde.

2 determining step for the preferred S linear aldehyde.

3 nc ion, which provides the activation of the aldehyde.

4 elf-sorted cages when combined with a linear aldehyde.

5 tropiporphyrin, and a N-methylcarbaporphyrin aldehyde.

6 3,5-triformyl benzene (TpOMe) as a precursor aldehyde.

7 d by a SmI(2)-mediated cyclization of a keto aldehyde.

8 C=C bond that usually forms the ketone of an aldehyde.

9 ylgermacrene D as well as dihydroartemisinic aldehyde.

10 key target intermediate, dihydroartemisinic aldehyde.

11 by mosquitoes-emit scents dominated by lilac aldehyde.

12 etones, and worst performance for ethers and aldehydes.

13 s were also added to the O-atoms of aromatic aldehydes.

14 miting access to many synthetically valuable aldehydes.

15 D469T/R520Q, that is active towards aromatic aldehydes.

16 ing from the (mostly) commercially available aldehydes.

17 ty through the sequential allylboration with aldehydes.

18 these two pathways for various alcohols and aldehydes.

19 with hydrogen and carbon monoxide to produce aldehydes.

20 omethylation and gem-difluoroalkenylation of aldehydes.

21 nt activity, and can quench various reactive aldehydes.

22 rect asymmetric alpha-allylation of branched aldehydes.

23 ed Stetter reaction of vinylphosphonates and aldehydes.

24 superoxide, proved capable of deformylating aldehydes.

25 a broad selection of alpha,beta-unsaturated aldehydes.

26 rmodynamically disfavored over the saturated aldehydes.

27 ing hydrogen peroxide, ammonia, and reactive aldehydes.

28 ll as their subsequent reaction with diverse aldehyde acceptors.

29 The preparation of these aldehydes/acetals, especially containing a tert-benzylic

30 yst features a N-terminal proline moiety for aldehyde activation and a thiourea unit for electrophile

31 Chiral Bronsted acid-catalyzed asymmetric aldehyde addition with the developed E-crotylboron reage

32 Subsequent aldehyde addition, however, operates under Curtin-Hammet

33 a and 23 aroma-active compounds, among which aldehydes, alcohols and ketones were the most prevalent

34 nerally evoked reduced responses to specific aldehydes, alcohols, aliphatics/aromatics, ketones, and

35 aldehydes, alcohols, ketones, aliphatic hydrocarbons, ar

36 typical Maillard reaction compounds such as aldehydes, alkyl pyrazines, and derivatives of furan.

37 Three different modes of aldehyde/alkyne assembly through a controlled radical re

38 hetero-multivalent glycomimetics comprising aldehyde, amine, and isocyanide components related to is

39 inning with an alkyl halide (derived from an aldehyde and an acyl bromide), an olefin, and a hydrosil

40 under 4 atm H(2) produced the corresponding aldehyde and cobalt hydride, demonstrating the feasibili

41 ntain complementary chemical moieties (e.g., aldehyde and hydrazide groups) that form covalent bonds

42 PVP with well-defined aldehyde and hydroxyl end groups lead to the formation o

43 n step is independent from hydrolysis to the aldehyde and instead can occur directly from the imine i

44 ry solvents, and is reported over a range of aldehyde and ketone substrates; a gram-scale process is

45 f nonenzymatic condensation of the rosamicin aldehyde and the octasaccharide everninomicin F, possess

46 nd basic conditions, alpha-substituted enone-aldehydes and 1,3-carbonyls undergo a Michael/aldol/hemi

47 ormation of aldimines from the corresponding aldehydes and 2-amino benzyl alcohols followed by NHC-ca

48 shale gas by reacting with CO(2) to produce aldehydes and alcohols.

49 to indenones, a concurrent oxidation of both aldehydes and alkynes in the course of their connection

50 lcohols and homoallylboronates into (chiral) aldehydes and allylboronates, respectively.

51 tion by cyclizations and oligomerizations of aldehydes and creatinine under usual cooking conditions.

52 ing of reactions that convert fatty acids to aldehydes and eventually alkanes would provide a means t

53 e (from a possible family of two amines, two aldehydes and four azides) with different volumes, ratio

54 s were observed at different brewing steps - aldehydes and furans dominate in wort, whereas the aliph

55 unctional groups and depleted of ketones and aldehydes and have higher solubility than nonbiological

56 rin, nicotine, and toxic substances, such as aldehydes and heavy metals, has been reported.

57 A wide range of aromatic aldehydes and ketones are tolerated and successfully con

58 anisylsulfanylmethylisocyanide, reacts with aldehydes and ketones in a BF(3).OEt(2)-mediated condens

59 Direct conversion of aldehydes and ketones into alkylboronic esters via deoxy

60 Nine lipid-derived unsaturated aldehydes and ketones may be responsible for the vegetal

61 Aldehydes and ketones required for their formation are p

62 precatalyst for the hydroboration of various aldehydes and ketones using HBpin as the hydrogen source

63 cesses in proceeding via the condensation of aldehydes and ketones with 2 equiv of an isocyanide foll

64 Uncharged carbonyl compounds (e.g., aldehydes and ketones) formed during oxidation have rare

65 tion through in situ enamine generation from aldehydes and ketones, the reaction scope for 3,6-bis(th

66 e same deoxygenation manifold with aliphatic aldehydes and ketones, we also enable a concise synthesi

67 lpha),C(ortho)-dilithiated phosphazenes with aldehydes and ketones.

68 enabled conjugate addition reactions between aldehydes and nitroolefins on a multigram scale in the a

69 ng-cleavage products, which were most likely aldehydes and organic acids, were observed but not quant

70 ion reaction and its application to ketones, aldehydes and other carbonyl derivatives, such amides, e

71 ion of unsaturated building blocks with aryl aldehydes and other carbonyl electrophiles to deliver a

72 case of reactions involving multifunctional aldehydes and primary amines, allow the formation of com

73 n of an achiral alpha-vinyl allylboronate to aldehydes and pseudo-axial orientation of the alpha-viny

74 Strecker aldehydes and pyrazines make an important contribution t

75 lavour was increased most when both Strecker aldehydes and pyrazines were increased together.

76 t structural constraint, via the coupling of aldehydes and secondary amines with alkyl halides.

77 -(OH)C(6)H(4), pyrrol-2-yl) originating from aldehydes and sterically hindered substituents (2-ClC(6)

78 One of the aldehydes and, consequently, all of the DCL members deri

79 amely, allyl, amine, carboxylic acid, thiol, aldehyde, and catechol, were prepared and chemically cha

80 oups: pyridine, pyrimidine, primary aniline, aldehyde, and ester.

81 cursors by first forming an alcohol, then an aldehyde, and finally eliminating formic acid with the i

82 reaction occurs between amino acid, aromatic aldehyde, and primary alcohol in alkaline solutions unde

83 ansfer of carbenes to olefins, heterocycles, aldehydes, and amines.

84 oil spill are also shown to contain ketones/aldehydes, and comparison of field and photo-oxidation-o

85 ss advantages and challenges associated with aldehydes, and derive strategies for the successful deve

86 -dihydro-pyrrolo[3,2-b]pyrroles from amines, aldehydes, and diacetyl, we confirmed that iron salts ar

87 uilibration was recorded with pyridine-based aldehydes, and dynamic oligomerization could be achieved

88 (3), and AlCl(3)) were treated with ketones, aldehydes, and esters.

89 ine, and important flavor compounds (esters, aldehydes, and ketones).

90 eparation, readily available and inexpensive aldehydes, and mild conditions make our procedure more e

91 t cascade cyclization reaction of alpha-keto aldehydes, anilines, activated alkynes, and aromatic nuc

92 red and electronically diverse pyrazoles and aldehydes, applicable for systematic ligand optimization

93 Aldehydes are by-products of increased oxidative phospho

94 Reactive aldehydes arise as by-products of metabolism and are nor

95 e amino acids was accomplished from Garner's aldehyde as a common starting point.

96 The scope of the method is explored using aldehyde as the acyl source.

97 tion reaction of 4,7-dihydroindole with aryl-aldehydes as an electrophilic partner followed by an oxi

98 Morita-Baylis-Hillman acetates of acetylenic aldehydes as C4 synthons, and simple imidazoles or benzi

99 jugation to enhance the potential of peptide aldehydes as therapeutics.

100 dichotomy between the increasing utility of aldehydes as tool molecules that bind to "undruggable" p

101 es 1,2-migration to give tert-alpha-arylated aldehydes (as acetals).

102 e reaction affords homocoupling of aliphatic aldehydes, as well as heterocoupling of aliphatic and ar

103 We discovered that short-chain aldehydes bind in an inverted fashion compared to secolo

104 ine proteases OTUB1 and OTUB2 (OTU ubiquitin aldehyde binding 1 and 2) are representative members of

105 have shown that OTU deubiquitinase ubiquitin aldehyde-binding 1 (OTUB1), a deubiquitinating enzyme of

106 those in the "aromatic box" that define the aldehyde-binding site.

107 to branched-chain amino acid (BCAA)-derived aldehyde biosynthesis in melon fruit.

108 ures depends on the geometrical match of the aldehyde building blocks.

109 nols, enhances the hydrogenation rate of the aldehyde by two effects, that is, polarizing the carbony

110 Notably, >95% efficient end capping with aldehyde can be achieved under optimized conditions.

111 mediates in NHC-catalyzed transformations of aldehydes, cannot undergo a single electron transfer (SE

112 addition of 3,3-disubstituted 2-oxoacids to aldehydes catalyzed by metal dependent 3-methyl-2-oxobut

113 n alpha- and enantioselective addition to an aldehyde, catalyzed by a proton-activated, chiral aminop

114 at glutamine amide 1 could select an optimal aldehyde component and preferentially assemble from mixt

115 ct on the plasmalogen content but influenced aldehyde composition, mainly in PE and in total PL.

116 ropanoic, acetic and butyric acid as well as aldehydes compounds, phenol and 1-octanol were detected

117 over several days to a structurally related aldehyde confirmed via NMR.

118 We therefore designed an aldehyde-containing analog capable of trapping Ser239 in

119 tion of ethanol to acetaldehyde generates an aldehyde-containing stream active for the production of

120 by periodate oxidation of kefiran, showed an aldehyde content of 23.6 +/- 0.9% that was confirmed by

121 estaurant-fried potato chip serving (FFRPCS) aldehyde contents were also monitored.

122 c/acyclic systems from the various propargyl aldehydes, cyclic/acyclic CH acids, and Hantzsch ester u

123 rrier protein (acyl-ACP) reductase (AAR) and aldehyde-deformylating oxygenase (ADO), which function i

124 tingly, 1 shows a nucleophilic reactivity in aldehyde deformylation reaction, demonstrating that 1 ha

125 tamoxifen and fulvestrant increased MFE and aldehyde dehydrogenase (ALDH) activity of patient-derive

126 roperties of NSCLC cells and increases their aldehyde dehydrogenase (ALDH) activity, which was identi

127 Samples were segregated based on their aldehyde dehydrogenase (ALDH) activity.

128 The structure shows that the aldehyde dehydrogenase (ALDH) and alcohol dehydrogenase

129 that VvAHGD and its homologs represent a new aldehyde dehydrogenase (ALDH) family with different subs

130 p53 and aldehyde dehydrogenase (ALDH) have been implicated in ke

131 kinase 1 (DCLK1), CD44 molecule (CD44), and aldehyde dehydrogenase 1 family member A1 (ALDH1A1).

132 ts, the expression of the quiescent markers: Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) and

133 ass of imidazo[1,2-a]pyridine derivatives as aldehyde dehydrogenase 1A3 inhibitors, reporting the evi

134 As the cytosolic enzyme aldehyde dehydrogenase 1A3 turns out to be overexpressed

135 ted with the use of disulfiram (DSF) a known aldehyde dehydrogenase 2 (ALDH2) inhibitor.

136 radical scavenger superoxide dismutase 1 and aldehyde dehydrogenase 2 was reduced, whereas the NOX2 (

137 normal myeloid counterparts, depended on the aldehyde dehydrogenase 3a2 (Aldh3a2) enzyme that oxidize

138 sion of ALDH1A1 and stem-related genes, high aldehyde dehydrogenase activity, and CD133 positivity.

139 ng hypoxia also increased glucose uptake and aldehyde dehydrogenase activity.

140 the monoamine oxidase TynA and the aromatic aldehyde dehydrogenase FeaB.

141 lls, thus proving the concept that targeting aldehyde dehydrogenase might represent a novel and promi

142 derstanding the evolution of the prokaryotic aldehyde dehydrogenase superfamily and their diversity o

143 s enzyme functions as a long-chain aliphatic aldehyde dehydrogenase.

144 Aldehyde dehydrogenases are versatile enzymes that serve

145 ); and oxidation of retinaldehyde into RA by aldehyde dehydrogenases family 1, subfamily A (ALDH1as),

146 ooxygenases, two alcohol dehydrogenases, two aldehyde dehydrogenases, a fatty-acid-CoA ligase, a fatt

147 -Villiger oxidation of a tetrahydrofuranyl-2-aldehyde derivative.

148 gler cyclizations of tryptophols and various aldehyde derivatives, showing strong rate accelerations

149 n scope with respect to the (hetero)aromatic aldehyde-derived aldimine and tolerates significant vari

150 describe a system that combines a salicylic-aldehyde-derived L,X-type directing group with an electr

151 We find that mice lacking two aldehyde detoxifying enzymes, mitochondrial ALDH2 and cy

152 uch as propanal, pentanal, hexanal, Strecker aldehydes, diacetyl, methyl glyoxal, 3-pentanone and 2-f

153 s the PSD reaction using distyrylbenzene-bis-aldehyde (DSB-3), whose reaction with PE produces a fluo

154 ith increasing molecular weight to favor the aldehyde due to van der Waals interactions of reaction i

155 ldehyde, acetone) and alpha,beta-unsaturated aldehydes (e.g., acrolein, crotonaldehyde) were quantifi

156 mosquito AL revealed that nonanal and lilac aldehyde each respectively activate the LC2 and AM2 glom

157 Aromatic aldehydes elicit their antisickling effects primarily by

158 The reaction affords aldehyde end-capped polymers whose molecular weight can

159 nto three different polymer-coated surfaces (aldehyde-, epoxy- and NHS ester-coated).

160 Acids, alcohols, aldehydes, esters and hydrocarbons only summed to ~3% of

161 al abundance of certain compounds (alcohols, aldehydes, esters, acids and terpenes).

162 ation was not observed, or seen weakly, with aldehydes, ethers, and ketones due to their strained fou

163 e-face, with a predicted ee of 85% for the S aldehyde (expt.

164 Our results suggest that NADPH diaphorase in aldehyde-fixed tissues is not enzymatic but is due to th

165 on between pyruvate derivatives, amines, and aldehydes for the preparation of phosphorus and fluorine

166 glucose plays an important role in reducing aldehyde formation by inhibiting the formation of o-quin

167 l organometallic transformations relevant to aldehyde formation.

168 le" protein sites and the designation of the aldehyde functional group as a structural alert by the m

169 On the other hand, the same enone-aldehydes generate new classes of fused-dihydrotropones

170 semble into high-symmetry cages-and the same aldehyde generates low-symmetry socially self-sorted cag

171 The STR catalysis of reactions of small aldehydes gives an unexpected switch in stereopreference

172 Additionally, an aldehyde group was introduced by C-H amidation, enabling

173 ary amine-based reagents that react with the aldehyde group, we uncovered evidence for abasic sites i

174 ng or an open-ring sugar with a reactive C1' aldehyde group.

175 onalization of aliphatic and benzoheteroaryl aldehydes has been developed using a transient ligand an

176 terocycles and N-heteroarenes with aliphatic aldehydes has been developed via oxidative decarbonylati

177 A)-catalyzed intramolecular cyclization with aldehydes has been developed.

178 vatives from nitroacetic esters and aromatic aldehydes has been developed.

179 onent cycloaddition of enoates, alkynes, and aldehydes has been developed.

180 utaconic acids, primary amines, and aromatic aldehydes has been further investigated.

181 The results show that alcohols and aldehydes have a distinct difference in their respective

182 amaru-type" homocrotylation, stereodivergent aldehyde homologations, radical hydroindation, and palla

183 al regioselectivity switch from aliphatic to aldehyde hydrogen atom abstraction upon deuteration of t

184 Two competitive oxidation processes generate aldehyde in situ via hydrogen transfer oxidation or (pse

185 and suppresses AM2, the high level of lilac aldehyde in the other orchid scents inverts this pattern

186 hioglycosylated dipyrromethanes and aromatic aldehydes in 15-21% yields.

187 the aerobic oxidation of alcohols to produce aldehydes in near quantitative yield and selectivity und

188 zoles, morpholino-nitroalkenes, and aromatic aldehydes in the catalysis of boron trifluoride etherate

189 ertains the role of the electronic effect of aldehydes in the formation of indene derivatives and tet

190 e produced by oligomerization of short-chain aldehydes in the presence of ammonia.

191 ld also be obtained by reacting bilanes with aldehydes in the presence of trifluoroacetic acid, follo

192 molecules studied, which yielded gamma-nitro aldehydes in very high yields (up to 95%), with high dia

193 trile and subsequent aldol condensation with aldehydes-in one pot.

194 nistration of the indole derivative indole-3 aldehyde increases proliferation of epithelial cells and

195 During this process, vitamin A aldehyde is shepherded within photoreceptors and retinal

196 The aldehyde, isobutanal, is the primary photoproduct of iso

197 ied water contained low concentrations of C6 aldehydes, isothiocyanates, nitriles, and sulfides, and

198 (A), carboxyls (C), and carbonyls or ketones/aldehydes (K) are separately profiled as individual chan

199 dies show that the insertion of Cu-H with an aldehyde, ketone, activated ester/amide, and unactivated

200 e air, CO, SO(2), NO, NO(2) and VOCs (mainly aldehydes, ketones and a carboxylic acid) were detected

201 f protonated monomers of alcohols, acetates, aldehydes, ketones, and ethers were produced in the reac

202 -unsaturated carbonylated products including aldehydes, ketones, esters, amides, and carboxylic acids

203 Besides aldehydes, ketones, or amines, starting materials have b

204 ynimide reagent include additions to imines, aldehydes, ketones, pyridinium salts, Michael acceptors,

205 ethers, arenes, alkyl aromatic systems, and aldehydes/ketones, having an alpha-phenyl ring have been

206 d and classified as alcohols, esters, acids, aldehydes, lactones, phenols, hydrocarbons and ketone.

207 Different activated aldehydes like ethyl glyoxalate and 2,2,2-trifluoroaceta

208 ecause of their ability to detoxify reactive aldehydes, like those generated from lipid peroxidation

209 e amide hit series is described in which the aldehyde makes a hemithioacetal reversible-covalent inte

210 and on the left kidney biochemical (malonyl-aldehyde [MDA], glutathione, oxidative stress [OSI], tum

211 Aldehyde moieties on 2D-supports or micro- and nanoparti

212 roach that selectively exploits the reactive aldehyde moiety at abasic sites to reveal their location

213 Aldehydes, nitrogenated species, and aromatic species we

214 ammonium acetate as the nitrogen source, and aldehydes (nontoxic and cheap alternatives of amines) fo

215 ated reductive coupling of aryl iodides with aldehydes occurs in a chemoselective fashion in the pres

216 re mixed together, choosing from one type of aldehyde, one amine and one azide (from a possible famil

217 wo phthalates, four acids, three esters, one aldehyde, one hydrocarbon and two alkyl phenol compounds

218 of dithiooxamide and two different aromatic aldehydes: one with strong electron-donating characteris

219 The reductive amination, the reaction of an aldehyde or a ketone with ammonia or an amine in the pre

220 oxidation of alcohols to their corresponding aldehyde or carboxylic acid is one of the most important

221 have been used that can be converted into an aldehyde or ketone (for instance, carboxylic acids or or

222 e product underwent a second allylation with aldehydes or acetals.

223 couple easily accessible carbonyl compounds (aldehydes or ketones) with ammonia, amines or nitro comp

224 Alcohols were oxidized to aldehydes or ketones, cyclic ethers to esters, and termi

225 Additions of Grignard reagents to aldehydes or methyl ketones provided no evidence for rin

226 tituted allylboronic acids were reacted with aldehydes or oxidized to alcohols in situ with a high de

227 beta-carbon, thus favoring the linear chiral aldehyde over the achiral branched alternative.

228 are associated with the loss of function of aldehyde oxidase (AOX1).

229 human cytochrome P450 3A4 (CYP3A4) and human aldehyde oxidase (hAOX) for more in-depth data interpret

230 d that 11a was not at risk of metabolism via aldehyde oxidase, an advantage over previously described

231 Aldehyde oxidases (AOXs) are a small group of enzymes be

232 uction studies, TaoR activates expression of aldehyde oxidoreductase aor and represses tungsten-speci

233 Profiting from an octa-aldehyde precursor complex, the ideal dimensions of the

234 of DNA are susceptible to alkylation by the aldehyde products of lipid peroxidation and by the metab

235 This enzyme cleaved the tripeptide aldehyde protease inhibitors, leading to the formation o

236 Nitroalkanes react specifically with aldehydes, providing rapid, stable, and chemoselective p

237 sorcinol, 1,3-dimethoxybenzene, and an alkyl aldehyde (R = C(1)-C(11)) along with BF(3).OEt(2) afford

238 ochloramine and dichloroacetaldehyde via the aldehyde reaction pathway.

239 ctivity relative to the structurally related aldehyde reductase was recorded.

240 -Spengler condensation of tryptamine and the aldehyde secologanin to give (S)-strictosidine as a key

241 A broad range of aldehydes, secondary amines with a cheaper ethyne equiva

242 leads to selective identification of ketone/aldehyde species by MS.

243 One bent aldehyde stands out as unable to assemble into high-symm

244 ed increase in harmful AR metabolites, toxic aldehydes, steatosis, ER stress, apoptosis, and liver in

245 configuration of the products by binding the aldehyde substrate differently.

246 an apolar binding site primed for aliphatic aldehyde substrate recognition.

247 g to the convergent evolution of the derived aldehyde synthase activity.

248 AS results in bifunctional switching between aldehyde synthase and decarboxylase activities.

249 says and a crystal structure suggest betaine aldehyde targets the gut microbial enzyme choline TMA-ly

250 Cell-penetrating peptide conjugated peptide aldehydes Tat-A and Tat-B showed low micromolar anticanc

251 e set of chemical classes such as pyrazines, aldehydes, terpenes, alcohols, esters, and ketones.

252 Formaldehyde (FA) is a simple biological aldehyde that is produced inside cells by several proces

253 e information about pharmacologically active aldehydes that are being used in humans.

254 volatile compounds (terpenes, phthalides and aldehydes) that contribute to its characteristic odour a

255 Diisopropylzinc alkylation of pyrimidine aldehydes-the Soai reaction, with its astonishing attrib

256 hydroformylation (AHF) of alkenes to chiral aldehydes, though a topic of high interest, the contempo

257 due to their easy preparation from aliphatic aldehydes through spontaneous condensation with hydroxyl

258 of a secondary alkylamine with an aliphatic aldehyde to form an all-alkyl-iminium ion, which is subs

259 transformations of indolines with alkenes or aldehydes to afford 3-alkylindoles and bisindolylmethane

260 nt catalytic method for direct conversion of aldehydes to branched or linear alkyl ketones is describ

261 ely promotes asymmetric Michael additions of aldehydes to challenging but biologically relevant heter

262 on in the presence of formaldehyde and other aldehydes to form 5,6-dihydro-7H-1,4-methanobenzo[e][1,4

263 STRs also accept short-chain aliphatic aldehydes to give enantioenriched alkaloid products with

264 2) enzyme that oxidizes long-chain aliphatic aldehydes to prevent cellular oxidative damage.

265 ylation of heterocycles and the oxidation of aldehydes to their corresponding carboxylic acids.

266 tive hydrogenation of alpha,beta-unsaturated aldehydes to unsaturated alcohols is a challenging class

267 substrate/cofactor, and suggest a potential aldehyde-transferring channel from AAR to ADO.

268 S is responsible for producing diformazan in aldehyde-treated tissues.

269 cal marker of nitric oxide synthase (NOS) in aldehyde-treated tissues.

270 substituted aromatic/heterocyclic/aliphatic aldehydes under aerial conditions using mixed aqueous me

271 orted for aromatic, alkenylic, and alkynylic aldehydes under mild reaction conditions, low catalytic

272 onverting amorphadiene to dihydroartemisinic aldehyde using a one-pot hydrosilylation/oxidation seque

273 reaction of functionalized benzyl halides to aldehydes using a super electron donor (SED).

274 lizable ketones, and aromatic/heteroaromatic aldehydes using ammonium acetate as an ideal promoter un

275 bonyls via aldol-decarbonylative coupling of aldehydes using robust and recyclable supported Pd catal

276 methylfurfural), acetovanillone and phenolic aldehydes (vanillin and syringaldehyde), while 4-ethylgu

277 at promote the adsorption of the unsaturated aldehyde via its C=O bond, most notably by electronic mo

278 ing stream active for the production of C(4) aldehydes via base-catalyzed aldol-condensation.

279 Here we report results of a novel aromatic aldehyde, VZHE-039, that mimics both the O(2)-dependent

280 , the ability of indole to scavenge Strecker aldehydes was also demonstrated in alanine/glucose and i

281 tionalized pyrroles and sterically demanding aldehydes was developed.

282 grees primary amines with electron-rich aryl aldehyde, we enable an oxidation and deprotonation event

283 gonal derivatizations of the enantioenriched aldehydes were performed without any decrease in enantio

284 A wide array of gamma-arylated aldehydes were readily accessed without preinstalling in

285 The results showed that aldehydes were the odorants with the highest aromatic im

286 ction with electrophiles including CO(2) and aldehydes, whereas CF(3) radical addition furnishes a wi

287 is demonstrated by reacting various aromatic aldehydes, which ascertains the role of the electronic e

288 o form thiol-reactive alpha,beta-unsaturated aldehydes, which then react with cysteine residues via M

289 e-3-ethanol, indole-3-pyruvate, and indole-3-aldehyde-which are derived from gut bacterial metabolism

290 action is used to couple an alpha-quaternary aldehyde with a vinyl iodide.

291 cid-catalyzed condensation of azulidipyrrane aldehydes with a dihydrodipyrrin carbaldehyde afforded t

292 ifically, we demonstrate alpha-alkylation of aldehydes with a turnover number (TON) of over 52,000 un

293 for the allylation of various alpha-branched aldehydes with different allylic alcohols.

294 tides were conjugated to various ketones and aldehydes with high efficiency by oxime ligation.

295 atives was achieved by reacting cyclopropane aldehydes with N'-aryl anthranil hydrazides in the prese

296 TRIP) catalyzes the asymmetric allylation of aldehydes with organozinc compounds, leading to highly v

297 aged 30, discovered the reaction of aromatic aldehydes with primary amines to give imine derivatives.

298 catalyze fluoropyruvate addition to diverse aldehydes, with exclusive (3S)-selectivity at fluorine t

299 evelopment of Hb modifiers, such as aromatic aldehydes, with the intent of increasing Hb affinity for

300 strategies for the successful development of aldehydes within drug discovery programs.