ライフサイエンスコーパス: alkyl

1 polymerases in bypassing major-groove O (6)-alkyl-2'-deoxyguanosine (O (6)-alkyl-dG) and minor-groov

2 f a range of 1-benzyl-(1,2,3-triazol-4-yl)-N-alkyl-(2-pyridinemethanimine) ligands and new complexes:

3 lectivities were observed with an array of 2-alkyl-, 2-aryl-, and 2-boryl-substituted 1,1-diboryl alk

4 starting materials such as 1,2-diamines and alkyl 3-oxohex-5-enoates and can be performed under solv

5 2-Alkyl, 3-alkyl-, and 2,5-dialkylpyiridines were produced

6 ty of 1-aryl-3-(arylthio)propan-2-ones and 1-alkyl-3-(arylthio)propan-2-ones with different aryl/viny

7 A collection of 42 novel alkyl 4-substituted-2-methyl-1,4-dihydrobenzo[4,5]imidaz

8 ion has been extensively used to make many 3-alkyl-5-(halomethyl)oxazolidin-2-ones, but the correspon

9 stereoconvergent synthesis of a series of 5-alkyl-, 5,5-dialkyl-, and 5,5,6-trialkyl-l-pipecolic aci

10 d, and allyl boronates, which may contain an alkyl-, a chloro-, or a bromo-substituted Z-alkene, can

11 GaBr(3) as a Lewis acid and terminal aryl or alkyl acetylenes as 1,6-zwitterion interceptors allows t

12 The environmental behavior of perfluorinated alkyl acids (PFAA) and their precursors was investigated

13 series of bis(4-fluorophenyl)methyl)sulfinyl)alkyl alicyclic amines, where the piperazine-2-propanol

14 ow as 0.1 mol % loading, providing protected alkyl, alkenyl and aryl amines in high yields with gaseo

15 (hetero)aromatic acids to the corresponding alkyl, alkenyl, alkynyl, and (hetero)aryl halides.

16 r the mono-selective installation of diverse alkyl, alkenyl, aryl, alkynyl, fluoro, hydroxyl and amin

17 agents, which produces products with two new alkyl-alkyl bonds.

18 ing approach, resembling formal and flexible alkyl-alkyl couplings, provides a general entry to synth

19 ee three-component coupling reaction of aryl alkyl/alkyl ketones, SeO(2), and phenols/anisoles is des

20 cohols from a variety of alcohols containing alkyl, allyl, benzyl and propargyl C-H bonds.

21 t allylic amination that can directly afford alkyl allylamines, enabled by the reactivity of thianthr

22 stituted dienes provide alpha-aryl and alpha-alkyl alpha-methyl-substituted nitriles, respectively.

23 al precursors, including those that generate alkyl, alpha-acyl, trifluoromethyl and sulfonyl radicals

24 ollowed by the reduction of the imine to the alkyl amine product.

25 scope since primary, secondary, and tertiary alkyl amines are accessible and hydrogen is the most att

26 Alkyl amines are intensively produced and use fine and b

27 of unactivated alkenes with simple secondary alkyl amines is preferentially achieved.

28 hnology, in particular for the attachment of alkyl amines to glutamine-containing peptides and protei

29 reospecific synthesis of useful alpha-chiral alkyl amines, and rapid construction of different ureas

30 lfonamide derivatives from the corresponding alkyl amines.

31 the first isolable boraphosphaketene, cyclic(alkyl)(amino) carbene (CAAC)-borafluorene-P=C=O (2), is

32 Herein, we report the synthesis of a cyclic (alkyl)(amino)aluminyl anion based on a five-membered fra

33 N-Heterocyclic carbene (NHC)- and cyclic (alkyl)(amino)carbene (CAAC)-stabilized borafluorene radi

34 ation, [(CAAC)(2)Be](+*) (2) [CAAC = cyclic (alkyl)(amino)carbene], prepared by oxidation of a zero-v

35 contain an alpha-stereogenic carbon with an alkyl, an aryl, a benzyloxy, or a siloxy moiety can be g

36 A wide range of secondary alkyl and aryl amines and primary and secondary alcohol-

37 educing end of short chain oligosaccharides, alkyl and aryl beta-D-glucosides and disaccharides.

38 This strategy conveniently engages alkyl and aryl halides in a wide range of redox transfor

39 Cross-electrophile coupling (XEC) of alkyl and aryl halides promoted by electrochemistry repr

40 Alkyl and aryl radicals generated thermally or photochem

41 lycyclic aromatic hydrocarbons (H-PAHs) with alkyl and aryl substitution are demonstrated.

42 amidic macrocyclic scaffold, whereas various alkyl and aryl urea substituents were introduced after a

43 With good functional-group tolerance, alkyl and benzyl amine derived PDIs (incl. commercial dy

44 ed and oxygenated alkanes, 8 alkenes, and 20 alkyl and halobenzenes were used to determine 39 paramet

45 e oxalates were then easily converted into N-alkyl and N-acyl analogues (RX, NaHCO(3)/DMF/100 degrees

46 type structure, with horizontal alternating alkyl and stacked aromatic layers in both the orange and

47 Cyclic (alkyl)- and (aryl)-(amino)carbenes (CAACs and CAArCs) ar

48 - to tetrasubstituted piperidines with aryl, alkyl, and carboxylic acid derivatives at multiple diffe

49 2-Alkyl, 3-alkyl-, and 2,5-dialkylpyiridines were produced by oligo

50 s, viz., cyclohexane, cyclic ethers, arenes, alkyl aromatic systems, and aldehydes/ketones, having an

51 We previously showed that an extended alkyl-aryl side chain is the key structural element dete

52 y and completely cleaved with functionalized alkyl-, aryl-, and H-tetrazines, irrespective of click o

53 either diastereomeric form-by reactions with alkyl-, aryl-, heteroaryl-, allyl-, vinyl-, alkynyl-, or

54 ive addition between palladium catalysts and alkyl/aryl electrophiles can be controlled by an OEEF ap

55 The production of alkyl/aryl radical in these methodologies required eithe

56 eated via incorporation of CO molecule to an alkyl/aryl radical.

57 semblies of 7,12-disubstituted cages from 7-(alkyl/aryl) NBDs, as well as the selective post-syntheti

58 dehyde with conjugated nitroalkene to give 2-alkyl/aryl-3-nitro-2H-chromenes in excellent enantiosele

59 We report tandem alkyl-arylations and phosphonyl-arylations of vinyl urea

60 he modular synthesis of diverse N-aryl and N-alkyl azaheterocycles (indoles, oxindoles, benzimidazole

61 Alternatively, the alkyl azide-bound congeners supported by a more sterical

62 thio)propan-2-ones with different aryl/vinyl/alkyl azides is reported under ambient conditions to fur

63 gly, the [3 + 2] cycloaddition of aryl/vinyl/alkyl azides with the in situ-generated equilibrated the

64 ctive cross-coupling between tosyl-protected alkyl aziridines and commercially available (hetero)aryl

65 chloroamines produced, conversion into tetra-alkyl aziridinium ions was possible, thus enabling diami

66 in expressing CndF and CndE, feeding various alkyl-beta-keto esters led to the biosynthesis of 6-subs

67 various downstream functionalizations of the alkyl boron compounds.

68 ion of C(sp(3))-rich and sterically hindered alkyl boron reagents in a practical and modular manner.

69 Alkyl boronic acids and esters play an important role in

70 trategic significance of this approach, with alkyl boronic acids as linchpins, is demonstrated throug

71 The synthesis of complex alkyl boronic esters through conjunctive cross-coupling

72 es efficient access to highly functionalized alkyl boronic esters.

73 L:B selectivities for internal alkenes with alkyl branches.

74 pure and enantiomerically enriched tertiary alkyl bromide, chloride, ester, and fluoride could there

75 gle electron transfer (SET) process with the alkyl bromide.

76 steady-state concentration of more-reactive alkyl bromide/iodide.

77 or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 r

78 The mild borylation of alkyl bromides and chlorides with bis(neopentylglycolato

79 ratory 3,3-difluoroallylation of unactivated alkyl bromides at remote tertiary centers.

80 ic and radical trapping studies with primary alkyl bromides suggest a unique mode of tertiary C-radic

81 onstrated by cross-coupling with unactivated alkyl bromides, generating a diverse array of aliphatic

82 f pharmaceutical precursors bearing aryl and alkyl bromides.

83 or vinyl bromides with primary or secondary alkyl bromides.

84 atalyst is faster than oxidative addition of alkyl bromides; (2) nickel bound metallocycles are invol

85 ted at the organo-organic interface, showing alkyl C and nitrogen (N) enrichment (by 4 and 7%, respec

86 eral methods for the trifluoromethylation of alkyl C-H bonds remain elusive.

87 e to incorporate fluoride ions directly into alkyl C-H bonds.

88 phatic-C (lipids, waxes) and retained more O-alkyl-C (carbohydrates), consistent with enhanced (13) C

89 Migration of N,N-Bis(2-hydroxyethyl) alkyl(C8-C18)amines from five different polypropylene ca

90 alkyl groups was achieved in reactions with alkyl carbastannatranes affording congested thioethers.

91 o show that two molecules with tails made of alkyl carbon, alkylphosphocholines (APCs) and quaternary

92 ethods to achieve transition-metal-catalyzed alkyl carbon-nitrogen (C-N) bond cleavage require the pr

93 Besides alkyl carboxylic acids, benzylic C(sp(3) )-H bonds also

94 ing of a dimethylsulfonium moiety and a long alkyl chain (C(18)-SMe(2)(+)), also induces production o

95 hioester leaving group contains a lipid-like alkyl chain - and a Cys-peptide modified by a lipid-like

96 n alkyne or an azide group at the end of the alkyl chain and with potential utility in bioorthogonal

97 phingosines (Cer[AS]) decreased, with larger alkyl chain lengths in Cer[NS], distinctly representing

98 es enable the introduction of functionalized alkyl chains at Cbeta, groups that have not yet been int

99 diacetylenic side chains and three saturated alkyl chains at different positions around the central H

100 ica substrates that were functionalized with alkyl chains containing head groups that mimic the IL ca

101 il was generally well tolerated, with longer alkyl chains enhancing analogue cytotoxicity.

102 l chains forming tight structures and longer alkyl chains forming larger pores with plate-like lipid

103 py, was lipid-length dependent, with shorter alkyl chains forming tight structures and longer alkyl c

104 cell membrane via the incorporation of long alkyl chains into a short polymer block leading to non-c

105 The molecules bear electronically inert alkyl chains of different length and bulkiness, attached

106 and strong hydrophobic interactions with the alkyl chains of the carrier.

107 flanked by two thiophene rings with branched alkyl chains.

108 electronic structure and bonding in uranium-alkyl chemistry.

109 Alkyl chlorides and aryl chlorides are among the most ab

110 t cross-electrophile coupling of unactivated alkyl chlorides and aryl chlorides.

111 Alkyl chlorides are bench-stable chemical feedstocks tha

112 electrophile coupling of aryl chlorides with alkyl chlorides has remained a challenge.

113 ntermediates, this synthetic [Fe(4)S(4)](3+)-alkyl cluster adopts an S = (1)/(2) ground state with g(

114 cterized the first synthetic [Fe(4)S(4)](3+)-alkyl cluster.

115 Here, we show that synthetic [Fe(4)S(4)]-alkyl clusters undergo Fe-C bond homolysis when the alky

116 a (ANKA) use enzymes homologous to MCR named alkyl-coenzyme M reductase (ACR).

117 , in particular the in situ synthesis of W=O alkyl complexes from their W carbyne analogues.

118 Homoleptic sigma-bonded uranium-alkyl complexes have been a synthetic target since the M

119 alytically active styrene-stabilized iron(0)-alkyl complexes.

120 Alkyl CPs also reduce the metabolic activity of pancreat

121 All these data demonstrate that the designed alkyl CPs are efficient photosensitizers for the photody

122 In Panc-1 cells, alkyl CPs at nanomolar concentrations promote a dramatic

123 confocal microscopy showed that the designed alkyl CPs strongly penetrate cell membranes, binding to

124 ere previously unreactive toward addition of alkyl-Cr reagents.

125 This work demonstrates the use of alkyl decoration in 3D COFs to tune their chemical stabi

126 over the initial 4-aryl analogues provided 4-alkyl derivatives with the desired functionality and goo

127 link the resulting compounds using flexible alkyl-derived linkers.

128 sine (O (6)-alkyl-dG) and minor-groove N (2)-alkyl-dG lesions in human cells, where the alkyl groups

129 O (6)-alkyl-dG lesions mainly induced G->A mutations that were

130 Replication across the two N (2)-alkyl-dG lesions was error-free, and Pol nu and Pol thet

131 hed mutation frequencies for all three O (6)-alkyl-dG lesions.

132 theta promote TLS across major-groove O (6)-alkyl-dG lesions.

133 -groove O (6)-alkyl-2'-deoxyguanosine (O (6)-alkyl-dG) and minor-groove N (2)-alkyl-dG lesions in hum

134 ups are ethyl, n-butyl (nBu), and, for O (6)-alkyl-dG, pyridyloxobutyl.

135 l hydroperoxide (TBHP) as the methyl source, alkyl diacyl peroxides as the primary alkyl source, alky

136 blastoma) for use as synthetic precursors of alkyl diazonium reagents.

137 s, the first example of a homoleptic uranium-alkyl dimer, [Li(THF)(4) ](2) [U(2) (CH(3) )(10) ], as w

138 lcogenation of sp(2) C-H bonds with aryl and alkyl disulfides as well as diphenyl diselenide.

139 ed deuterium labeling at specific sites of N-alkyl drugs is crucial in drug-development as over 50% o

140 To our surprise, alkyl electrophiles follow a hitherto unexplored S(N)2 p

141 h the catalytic carboxylation of unactivated alkyl electrophiles has reached remarkable levels of sop

142 (NHCs) has enabled reactions of unactivated alkyl electrophiles not only limited to the traditional

143 C-F bond-forming reactions using unactivated alkyl electrophiles.

144 /mL) following oral administration of simple alkyl ester prodrug and activated ester prodrug, respect

145 The determination of the fatty acid alkyl esters renders useful only when the deodorized mat

146 ng to 1-alpha-(pyridyl-2-[1,2,4]triazolyl)-2-alkyl-ethanones has been discovered while studying the r

147 of perfluorosulfonic acids and homologues of alkyl ether sulfates (C(8)- and C(10)/EO(n), C(8)H(17)(C

148 sting the protecting group strategy, from an alkyl ether to a bidentate ketal at the carbohydrate bac

149 ic potential of six synthetic hydroxytyrosyl alkyl ethers (HT C1, C2, C4, C6, C8 and C12).

150 iant of this reaction via the coupling of an alkyl fragment with an alkyl-iminium ion that is generat

151 on of commercial bis(pinacolato)diboron with alkyl Grignard compounds.

152 orresponding nucleosides by coupling aryl or alkyl Grignard reagents and halogenated purine nucleosid

153 aromatic substitution and replacement of an alkyl group by the nucleophilic alpha-C atom of the phos

154 The cannabinoid alkyl group is a critical structural feature that govern

155 athway, repulsion between the ligand and the alkyl group is minimized (by virtue of it being 1 degree

156 This method permits iterative alkyl group transfer from tertiary amines and demonstrat

157 ses a coordinated diisopropylzinc moiety for alkyl group transfer.

158 n of racemic cyclic diolides (rac-8DL(R) , R=alkyl group).

159 The alkyl groups and the heteroaromatic core play further co

160 )-alkyl-dG lesions in human cells, where the alkyl groups are ethyl, n-butyl (nBu), and, for O (6)-al

161 Fluorinated alkyl groups are important motifs in bioactive compounds

162 A number of amines with three bulky alkyl groups at the nitrogen, which surpass the steric c

163 ted pyridyl moieties in position 4 and small alkyl groups in position 2 provided the best profiles.

164 imization of steric interactions between the alkyl groups of the diol on boron and the chiral phospho

165 A selective transfer of alkyl groups was achieved in reactions with alkyl carbas

166 bstituted glycoluril subunits with different alkyl groups were designed, synthesized, and fully chara

167 ble with a host of sterically differentiated alkyl groups, alkenes, acidic protons alpha to carbonyl

168 ituted, tetracyclic indoline derivative with alkyl groups, employing a mild Negishi C-C bond forming

169 over 50% of the top-selling drugs contain N-alkyl groups, in which it is very challenging to selecti

170 Owing to the strong hydrophobicity of the alkyl groups, the resultant COFs show high crystallinity

171 wo TLS polymerases and the structures of the alkyl groups.

172 n when the two substituents are both primary alkyl groups.

173 her two aryl, one aryl and one alkyl, or two alkyl groups; 3-aminocyclohex-2-en-1-ones of this type a

174 synthesis of such esters, beginning with an alkyl halide (derived from an aldehyde and an acyl bromi

175 protocols with tert-alkyl organometallic or -alkyl halide reagents, and it enables the expedient form

176 Three new dimeric bis-guanidinate zinc(II) alkyl, halide, and hydride complexes [LZnEt](2) (1), [LZ

177 catalyst for the selective cross-coupling of alkyl halides and allylic halides to form C-C hydrocarbo

178 broad substrate scope that included tertiary alkyl halides and heteroaromatic boronic esters.

179 ross-coupling reactions between a variety of alkyl halides and unactivated aryl boronic esters using

180 te that a silylcopper intermediate activates alkyl halides by single electron transfer to form alkyl

181 Their classic generation from alkyl halides has a severe drawback due to the employmen

182 yzed carbonylative silylation of unactivated alkyl halides has been developed, enabling efficient syn

183 um fluoride for nucleophilic fluorination of alkyl halides is an important challenge because of the h

184 hatic alcohol derivatives with both aryl and alkyl halides is disclosed.

185 e reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoi

186 employ readily available starting materials (alkyl halides, alkenes, etc.) and simple, transition-met

187 quenched with various electrophiles such as alkyl halides, epoxides, Michael acceptors, and lambda(3

188 eptible to nucleophilic substitution such as alkyl halides.

189 pling of aldehydes and secondary amines with alkyl halides.

190 ivity was obtained for primary and secondary alkyl halides.

191 catalyzes efficient installation of reactive alkyl handles, (iii) the X-ray crystal structure of TnmH

192 ch oligonucleotide, in combination with an N-alkyl imidazole organocatalyst.

193 ia the coupling of an alkyl fragment with an alkyl-iminium ion that is generated in situ(10-14).

194 hrough the addition of alkyl radicals to all-alkyl-iminium ions.

195 an be achieved by inhibitors that occupy an "alkyl-induced" pocket and possess bicyclic hinge-binding

196 ubstituents into both the "selectivity" and "alkyl-induced" pockets within the adenosine triphosphate

197 c rearrangements through the intermediacy of alkyl iodanes as stereodefined carbocation equivalents.

198 rlaps the absorption spectrum of a key Pd(II)alkyl iodide intermediate, the reaction proceeds with 82

199 ue light-promoted iodination is used to form alkyl iodide intermediates from simple unreactive alcoho

200 n enantioselective radical cyclization using alkyl iodides as precursors to unstabilized nucleophilic

201 valuated for a series of linear and branched alkyl iodides with increasing structural complexity by m

202 ic amines from readily available 1,3-dienes, alkyl iodides, and amines.

203 n nitrile rubber gloves, and considered that alkyl isothiocyanate might also have played a causative

204 ryl, heteroaryl, alkynyl, alkenyl, allyl, or alkyl ketones that contain an alpha-stereogenic carbon w

205 ration of l-tyrosine- or l-leucine-derived 4-alkyl-l-proline derivatives (APDs) in their structures.

206 initiating enzyme of prokaryotic NER, to an alkyl lesion by ATL.

207 Alkyl-ligated iron-sulfur clusters in the [Fe(4)S(4)](3+

208 yloxycarbonyl (Benzyl) and ethyloxycarbonyl (Alkyl) linkers, respectively.

209 Here, we show that mono-alkyl lipophilic cations (MALCs) inhibit oxidative phosp

210 Herein, we report the activity of aryl-alkyl-lysines against C. difficile and associated pathog

211 Aryl-alkyl-lysines have been earlier reported to possess anti

212 Overall, the findings suggest aryl-alkyl-lysines warrant further investigation as novel age

213 ons and competing isomerizations of tertiary alkyl metal intermediates.

214 rms a bimetallic complex upon treatment with alkyl metal reagents, such as Et(2) Zn and Bu(2) Mg.

215 metal acts as a precursor to alpha- or beta-alkyl migration steps that break the C-C sigma bond.

216 ile lipophilic-lipophilic association of the alkyl moieties and complementary perfect fit of the tria

217 2-Aryl and alkyl monosubstituted dienes provide alpha-aryl and alph

218 nable for a multi-gram scale-up to deliver 2-alkyl-N-arylindoles in high yields followed with only a

219 kes advantage of an in situ generated chiral alkyl Ni(III)-intermediate to ensure a stereodefined out

220 To do so, it uses exclusively N-alkyl nicotinamide derivatives, without being able to re

221 Such compounds formed gamma-C-(alkyl)-nucleoside triphosphate analogues with high selec

222 rapid beta-hydrogen elimination from cobalt alkyls occurred under an N(2) atmosphere, alkylation of

223 es of the general formula RPM(CO)(n) (R = an alkyl or aryl group; M = a transition metal) are electro

224 s to [(IMes)(3)Fe(4)S(4)-R](+) clusters (R = alkyl or benzyl; IMes = 1,3-dimesitylimidazol-2-ylidene)

225 stituents, either two aryl, one aryl and one alkyl, or two alkyl groups; 3-aminocyclohex-2-en-1-ones

226 to the existing coupling protocols with tert-alkyl organometallic or -alkyl halide reagents, and it e

227 results illustrate that the chain-walking of alkyl-palladium complexes can be controlled through the

228 The formation of alkyl-palladium complexes via the nucleopalladation of a

229 One possibility is that the intermediate alkyl-Pd complexes can undergo a "chain-walking" event,

230 Alkyl-Pd(IV) complexes are frequently invoked in the pro

231 of stable and isolable OCO pincer-supported alkyl-Pd(IV) complexes containing cyclopalladated alkyla

232 works, which represent the first examples of alkyl-Pd(IV) complexes derived from the oxidation of cyc

233 9'-spirobifluorene (spiro-MeOTAD), while the alkyl pending groups affect molecular packing in thin fi

234 iacyl peroxides as the primary alkyl source, alkyl peresters as the secondary and tertiary alkyl sour

235 alcohol-derived 2-methyl-2-tetrahydropyranyl alkyl peroxides (MTHPs) in tetrahydrofuran at 0 degrees

236 eoside triphosphate analogues comprising a C-alkyl-phosphonate moiety replacing the gamma-phosphate.

237 Alkyl phosphotriester (alkyl-PTE) lesions are frequently

238 analogues reveals that incorporation of C-24 alkyl phytosterols into LNPs (eLNPs) enhances gene trans

239 ndings provide in-depth understanding of how alkyl-PTE lesions are recognized by the DNA replication

240 Alkyl phosphotriester (alkyl-PTE) lesions are frequently induced in DNA and are

241 illard reaction compounds such as aldehydes, alkyl pyrazines, and derivatives of furan.

242 A nickel terpyridine catalyst couples N-alkyl pyridinium salts with in situ formed carboxylic ac

243 pump is related to an impaired production of alkyl quinolone QS signals, likely prompted by the reduc

244 means of the electroreductive generation of alkyl radical and carbanion intermediates.

245 halides by single electron transfer to form alkyl radical intermediates and that carbon-halogen bond

246 s enabled the discovery of a plethora of new alkyl radical precursors, opening the world of radical c

247 Competition kinetic experiments reveal that alkyl radical substitution on tetrasulfides is a rapid r

248 oxy hydroperoxide, trapping of the generated alkyl radical with 2,2,6,6-tetramethylpiperidin-1-yl (TE

249 A cleaves C-H bonds in the alkane to form an alkyl radical, which subsequently reacts with mCPBA to a

250 susceptible to beta-fragmentation, releasing alkyl radicals and affording imines, which in turn are s

251 ng ones that produce highly reactive primary alkyl radicals and those containing functional groups th

252 A subsequent beta-scission event liberates alkyl radicals for coupling with electron-deficient olef

253 ity of Eosin Y for a reductive generation of alkyl radicals from N-(acyloxy)phthalimide esters.

254 tertiary alkylamines through the addition of alkyl radicals to all-alkyl-iminium ions.

255 DH and analogues have been found to generate alkyl radicals upon reductive decarboxylation of redox-a

256 ent "ene"-reductases can generate stabilized alkyl radicals when irradiated with visible light; howev

257 ther carboxylic acids to generate methyl and alkyl radicals, respectively, without the need for stoic

258 uggest that the reaction occurs through free alkyl radicals.

259 exotine A that likely originates from a 1,2-alkyl rearrangement of a protonated 3,3'-spiroindolenine

260 aziridine moiety and the latter with an NCO-alkyl residue (imide or carbamate).

261 differ drastically in aromatic backbone and alkyl side chain chemistry.

262 controlling the degree of crystallinity and alkyl side chain length.

263 henylphosphonium-conjugated ATO with varying alkyl side chains (Mito(4)-ATO, Mito(10)-ATO, Mito(12)-A

264 phene ring backbones separated by insulating alkyl side chains.

265 of 13 degrees C for conjugated polymers with alkyl side chains.

266 Genetic enhancement of the alkyl side-chain could lead to the development of novel

267 low swelling, attributed to the hydroxylated alkyl side-chain functionalization.

268 ketide fatty acid starter unit synthesis and alkyl side-chain length.

269 systematically replacing a certain amount of alkyl side-chains with compact bulky side-chains (CBS).

270 ource, alkyl diacyl peroxides as the primary alkyl source, alkyl peresters as the secondary and terti

271 lkyl peresters as the secondary and tertiary alkyl sources, and aryl diacyl peroxides as the arylatin

272 y is the initial formation of TMEDA-iron(II)-alkyl species which undergo a controlled reduction to se

273 n, the intermediacy of (phenanthroline)Ni(I)-alkyl species-complexes proposed in numerous Ni-catalyze

274 roducts coated with per- and polyfluorinated alkyl substances (PFAS).

275 droxylation of the ring and oxidation of the alkyl substituent accounted for approximately 15-40% of

276 es as 1,6-zwitterion interceptors allows the alkyl substituent to be grown to give the corresponding

277 In addition, alkyl substituents are not tolerated, and the N-H proton

278 ducts of ring hydroxylation and oxidation of alkyl substituents as well as a suite of ring-cleavage p

279 ng currents and the presence of the internal alkyl substituents had little effect on the global aroma

280 P1-P3 subsites of 21 is functionalized with alkyl substituents, which are shown to effectively modul

281 successfully implemented for alkenes bearing alkyl substituents.

282 atalysts to provide the corresponding 2-aryl(alkyl) substituted 4-(trifluoromethyl)quinolin-3-ylphosp

283 n developed, enabling efficient synthesis of alkyl-substituted acylsilanes in high yield.

284 th SO(2) and formic acid, similar to smaller alkyl-substituted CIs, and by contrast, slow removal in

285 The steric demand of the electron-rich, alkyl-substituted double bond determines the reaction pa

286 e one-pot procedure for the preparation of 2-alkyl-substituted N-arylindoles is described.

287 atalyzed allylic substitution of challenging alkyl-substituted secondary allylic carbonates with benz

288 nucleophiles to a simple, readily-accessible alkyl sulfinyl (IV) chloride allows formation of a trigo

289 of hydroboration/selective protodeborylation/alkyl-Suzuki coupling used to close the 11-membered ring

290 designs of p(glycerol monomethacrylate)-b-p(Alkyl-TAF-methacrylate) and p(glycerol monomethacrylate)

291 The homopolymer depots with p(Alkyl-TAFMA) exhibited sustained TFV and TAF release pro

292 tate small molecule compatibility with 3HM's alkyl tail core.

293 DOX promoted crystalline alkyl tail ordering, which significantly increased (+63%

294 enhances gene transfection and the length of alkyl tail, flexibility of sterol ring and polarity due

295 s a unified method to access diaryl and aryl alkyl thioethers and was demonstrated in the context of

296 The oxidation of alkyl thiols to disulfides has been achieved under mild

297 (or bromo)-5-(1'-Me(3)SiO-1'-trifluoromethyl-alkyl)thiophenes in Bronsted superacids (CF(3)SO(3)H, FS

298 upramolecular assemblies formed by synthetic alkyl triazole-based amphiphiles against interfaces of t

299 on, we previously quantified interactions of alkyl ureas with amide and aromatic compounds, relative

300 alkynes, silicon electrophiles, and primary alkyl zinc iodides.