ライフサイエンスコーパス: all-or-none

1 ain why subjective experience of VSTM is not all or none.

2 FCCP, showed a response that was essentially all-or-none.

3 ne and sorbitol were found to be essentially all-or-none.

4 ess of exocytosis in model cell lines is not all-or-none.

5 item, suggesting that such failures are not all-or-none.

6 veals that this behavior is the result of an all-or-none abrupt solubilization of individual aggregat

7 e type of dye release changed from graded to all-or-none according to prediction.

8 a postganglionic nerve trunk evoked direct, all-or-none action currents and delayed nicotinic EPSCs

9 rendering codes that are based on classical, all-or-none action potentials unworkable.

10 g information only by the timing and rate of all-or-none action potentials.

11 ed-pulse depression, large initial EPSPs, an all-or-none activation profile, and no metabotropic rece

12 and NFAT-dependent gene expression display "all-or-none" activation that is exclusively driven by lo

13 nule cell layer in cerebellar slices elicits all or none alpha-amino-3-hydroxy-5-methyl-4-isoxazolepr

14 ion and to climbing fiber input with a large all-or-none AMPA-mediated EPSP that shows paired pulse d

15 The all-or-none and composite care summary measures were als

16 udoknots, natural resistance was essentially all-or-none and correlated with the identity of the amin

17 Unitary plasticity events were all-or-none and drove synaptic strength between extremes

18 ties, where graded inputs are converted into all-or-none and hybrid responses.

19 lenge the view that these calcium spikes are all-or-none and only signal whether the instructive stim

20 n are characterized better as graded than as all-or-none and that priming need not arise from a mecha

21 ganized and capable of gradual, oscillatory, all-or-none, and subpopulation-generating responses.

22 ded in the axon at distances > 25 microm are all-or-none, and uniform in amplitude even when action p

23 That an all-or-none apparent sex difference in neuronal types is

24 heir large size, paired-pulse depression and all-or-none appearance in response to a graded stimulus.

25 mossy fibre inputs were identified by their all-or-none appearance in response to a graded stimulus.

26 herence to individual discharge measures and all-or-none appropriate care measures for acute myocardi

27 scle, C. elegans body-wall myocytes generate all-or-none APs, which evoke Ca2+ release from the sarco

28 alyzed DNA unwinding is often studied using "all or none" assays that detect only the final product o

29 , when coupled, the population was recruited all-or-none at threshold into a rhythmic swimming patter

30 such as NtrC1 or PspF, a novel cis-mediated "all or none" ATP binding occurs in the heptameric FlrC(C

31 Particulate Ag induces potent 'all-or-none' B cell responses that are density dependent

32 cs of the VRC reconfigure from rotational to all-or-none, ballistic efforts.

33 This all-or-none behavior suggests a mechanism by which chrom

34 transporter and reporter plasmids, exhibited all-or-none behavior.

35 ees C or greater, which was indicative of an all-or-none behavior.

36 nse to the inducer galactose as well as the "all-or-none" behavior characteristic of many eukaryotic

37 ic response reveals ultrasensitivity and an "all-or-none" behavior, hallmarks of a bistable switch me

38 oidal response to stimulation amplitude (an 'all-or-none' behavior), appearance in multiple observabl

39 emonstrating that both can show regenerative all-or-none behaviour.

40 At a fixed site, the response is close to 'all-or-none' behaviour which suggests that calcium spark

41 ation-inducing hormone progesterone, into an all-or-none biological response-oocyte maturation.

42 cing of Sxl primary transcripts generates an all-or-none bistable behavior and constitutes an efficie

43 ochasticity results in the observation of an all-or-none bistable response over a much wider range of

44 lts and that regulatory factors may not make all-or-none, black-or-white contributions to infectivity

45 f both elt-7 and elt-2 results in a striking all-or-none block to morphological differentiation of gr

46 nversions of signaling gradients into sharp "all-or-none" borders are fundamental to tissue and organ

47 xamined the ionic conductances that underlie all-or-none burst firing elicited in acutely dissociated

48 Cerebellar Purkinje neurons often generate all-or-none burst firing in response to depolarizing sti

49 in the superior colliculus gives rise to an all-or-none burst response that signals threshold crossi

50 show that graded leakage can be converted to all-or-none by simply adding a defect-promoting lysophos

51 continuous pool, but rather, it is due to an all-or-none Ca(2+) release from a compartmentalized Ca(2

52 e been proposed to resolve this paradox: (i) all-or-none Ca(2+) release from heterogeneous stores tha

53 lace the in vivo resting MET current, evoked all-or-none calcium spikes (39-75 mV amplitude) in 37% o

54 c motor neurons AVL and DVB fire synchronous all-or-none calcium-mediated action potentials following

55 ar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stim

56 als with EHRs had similar odds of receiving "all-or-none" care (odds ratio [OR]: 1.03; 95% CI: 0.99 t

57 we show that [4]-ladderane always exhibits 'all-or-none' cascade mechanoactivations and the same ste

58 ients of extracellular signals into discrete all-or-none cellular responses, such as mitogenesis and

59 he acid side of the profile, compared to the all or none change observed for wt giving a p K a of abo

60 y distinct cellular identities by triggering all-or-none changes in expression of combinations of tra

61 Here evidence is presented that the all-or-none character of the response is generated by th

62 ings provide a biochemical rationale for the all-or-none character of this cell fate switch.

63 The all-or-none character of transmission at central synapse

64 This assumption leads frequently to an "all or none" choice of either preserving coastal habitat

65 tipolar Purkinje cells showed characteristic all-or-none climbing fiber responses.

66 in the cerebellar cortex, where they elicit all-or-none complex spikes and control major forms of pl

67 ormance, adherence measured through a global all-or-none composite infection-prevention score was ass

68 ures (S-INF) were aggregated into 2 separate all-or-none composite scores.

69 (constitutively active CREB) would break the all-or-none concordance.

70 of bacterial genes are found to exhibit an 'all-or-none' control mechanism that adapts the bacterium

71 tion of hERG1 channels involves a concerted, all-or-none cooperative interaction between all four sub

72 onstrate that, in contrast to the canonical "all or none" coregulator switch model, THs regulate gene

73 In this study, sensory-evoked all-or-none cortical population responses were observed

74 the oxidative stress stimulus, leading to an all-or-none cytoprotective or pro-apoptotic signaling re

75 a model explaining this complex, stochastic all-or-none dataset.

76 ltiple internal and external signals into an all-or-none decision to enter the cell cycle.

77 ed on genomic biomarkers generally entail an all-or-none decision, which may be misleading for clinic

78 bicans to 'test the waters' before making an all-or-none decision.

79 uggest that target predictions must consider all or none decisions by individual seed nucleotides.

80 review preclude their widespread use to make all-or-none decisions about whether to screen individual

81 Thus, the all-or-none definition of essentiality afforded by tradi

82 n of 1 pA of current triggered a maintained 'all-or-none' depolarization to a plateau of -34 mV, asso

83 timing of the shock, demonstrating a classic all-or-none depolarizing response.

84 muscle-type proprioceptor character, we find all-or-none differences in gene expression for proprioce

85 s at which graded signals are converted into all-or-none distinctions in cell identity remain poorly

86 As such, this is an "all-or-none" DNA unwinding assay.

87 ed indicated that the beta-subunit exerts an all-or-none effect on the Ca2+ sensitivity and kinetics

88 raded release in general, which, contrary to all-or-none efflux, has not been well-understood.

89 monocular deprivation triggers a complete, "all-or-none," elimination of connections from pyramidal

90 tal-like output, we envisage that the use of all-or-none enzymatic responses will also improve our ab

91 T input and 30% with IX input responded with all-or-none EPSCs.

92 ontaining m bp, each of which experiences an all-or-none equilibrium between a straight and a uniform

93 e show that regenerative CICR develops as an all-or-none event in cultured rat dorsal root ganglion n

94 ve examined whether channel maturation is an all-or-none event or whether heterogeneous processing of

95 s within an individual channel complex is an all-or-none event such that channels present on the cell

96 lar signaling by antigen receptors is not an all-or-none event, and these external variables alter bo

97 like the peristaltic reflex, the CMMC is an 'all or none' event that appears to be dependent upon Dog

98 ld view that the climbing-fibre input is an 'all-or-none' event.

99 he initiation of bidirectional plasticity by all-or-none events may help confer robustness on memory

100 ods, spike metrics operate on time series of all-or-none events, and are, thus, particularly appropri

101 tors, silencing and reactivation occurred in all-or-none events, enabling the regulators to modulate

102 All-or-none failures of multiquantal IPSC components als

103 nd GF, with both cell types responding in an all or none fashion when measured at day 2, and in a con

104 nzyme rapidly, stoichiometrically, and in an all or none fashion, rather than variably over a large r

105 of contents from lipid vesicles occurs in an all-or-none fashion and the differences between PC/PG 50

106 all proteins fold highly cooperatively in an all-or-none fashion and thus their native states are wel

107 ural circuits can be readily modulated in an all-or-none fashion at the single synapse level when ope

108 analysis showed that ERK is activated in an all-or-none fashion in both wild-type and KSR1-deficient

109 lti-switch", directing differentiation in an all-or-none fashion to a specific cell-type chosen among

110 diversion to a myeloid-like phenotype, in an all-or-none fashion with multiple, coordinate gene expre

111 the kinesin-based microtubule movement in an all-or-none fashion without lowering kinesin ATPase acti

112 translocation into the nucleus occurs in an all-or-none fashion, dependent on complete dephosphoryla

113 f one neuron in a network could evoke, in an all-or-none fashion, reverberatory activity lasting for

114 tranded form that was saturated by g5p in an all-or-none fashion.

115 nd S2 in the absence of force proceeds in an all-or-none fashion.

116 s consecutive unfolding of each domain in an all-or-none fashion.

117 ted by the dosage compensation pathway in an all-or-none fashion.

118 nchback (hb) gene in the anterior half in an all-or-none fashion.

119 als are thought to release transmitter in an all-or-none fashion; either one synaptic vesicle undergo

120 ng alleles in which exon 3 is spliced in an "all-or-none" fashion.

121 hexameric HerA binds six nucleotides in an 'all-or-none' fashion, HerA-NurA harbors a highly coordin

122 iring, and brief depolarization then induced all-or-none firing of conglomerate action potentials com

123 Graded and all-or-none fluxes correspond to unimodal and bimodal di

124 strong for the other that crowding should be all-or-none for both.

125 ts, but the leakage mechanism was different (all-or-none for PI and graded release for PIP vesicles).

126 gamma1:alpha-subunits, the results reveal an all-or-none functional regulation of BK channels by gamm

127 f function (efficiency alleles), rather than all-or-none, gain-of-function, or loss-of-function allel

128 This all-or-none, global electrical and biochemical signaling

129 triggering (a probabilistic process that is all-or-none in a single simulation).

130 surface activation marker, were essentially all-or-none in character.

131 nses of cooperative enzymes; or bistable and all-or-none in character.

132 1 and help make the process irreversible and all-or-none in character.

133 nose-inducible promoter P(BAD) is subject to all-or-none induction, in which intermediate concentrati

134 Surprisingly, we find an "all-or-none" infection clearance response: the most-dise

135 ller than that of dye flux through the pore, all-or-none influx occurs.

136 well suited to being a Ca2+ sensor for rapid all-or-none intercellular membrane-related events.

137 on of afferents from area X evoked a strong, all-or-none IPSP whose amplitude and latency were unchan

138 But overall, magainin follows the same all-or-none kinetic model as cecropin A in these lipid m

139 The all-or-none kinetic model that we recently proposed for

140 tiated synapses, and (4) both LTP and HD are all-or-none, leading de facto to binary-valued synaptic

141 enon of contents release, together with some all-or-none leakage (at low ceramide concentrations or s

142 ent of a quantitative model where graded and all-or-none leakage are treated as a continuum explained

143 These species are stable, result in all-or-none leakage, and represent a definable protein/l

144 channels in the bilayer should cause only an all-or-none leakage.

145 tic rescue was possible even using a simple, all-or-none light input that reduced the gradient of Erk

146 erefore, melting behavior of the hairpins is all-or-none like.

147 two RP states are exchangeable mainly due to all-or-none-like conductance changes of the inward-recti

148 d that transmission of frequency signals is "all-or-none", limited by a critical frequency (f(c)).

149 All-or-none LOI could lead to a second distinct cell pop

150 tic guests can be captured or released in an all or none manner upon chemical command.

151 d to cdG, they work together with RcdA in an all-or-none manner to reduce the Km of CtrA proteolysis

152 found that ICRAC activates in an essentially all-or-none manner when the current is evoked by recepto

153 ction potentials propagate along axons in an all-or-none manner, subthreshold membrane potential fluc

154 They are defined in an all-or-none manner, whereas they actually present a wide

155 ike phenotype only previously observed in an all-or-none manner.

156 ted chloride currents that were evoked in an all-or-none manner.

157 ors in single spines depressed rapidly in an all-or-none manner.

158 andles show that they unfold in a reversible all-or-none manner.

159 individual chromosomal copies of TMS1 in an all-or-none manner.

160 physiological and pathological stimuli in an all-or-none manner.

161 able steady state directly to another, in an all-or-none manner.

162 the anterior half of the embryo in a nearly all-or-none manner.

163 ation is the proposed source of the digital (all or none) MAPK responses following antigen stimulatio

164 The popular "all-or-none" measurement approach was also dominated by

165 Instead of an all-or-none mechanism of allostery, these findings suppo

166 optotic Bax forms large, stable pores via an all-or-none mechanism that can release cytochrome c.

167 e contents are released, consistent with the all-or-none mechanism.

168 c model is implemented for a peptide with an all-or-none mechanism.

169 ated, was relatively constant, suggesting an all-or-none mechanism.

170 ite QI was calculated through the use of the all-or-none method.

171 slope of 1.0, a tell-tale characteristic of all-or-none mnemonic representations.

172 We present a simple two-state, all-or-none model for bimolecular hybridization of non-s

173 econdary structure profiles as multivariant, all-or-none models, which subsume covariant models.

174 In contrast, the all-or-none motor patterns underlying wing expansion are

175 ic potentials (EPSPs) of regular (n =76) and all-or-none (n =24) type in layer 2/3 pyramidal cells in

176 The widely adjustable, all-or-none nature of the switch, combined with the long

177 Chemosensitivity is not an all-or-none neuronal property, and the degree of chemose

178 t these oscillators operate best with either all or none of their intersegmental inputs.

179 to which these causal factors explain some, all, or none of the genetic heritability, as measured by

180 se results reveal a complex response, not an all-or-none one, which results in multiple effector phen

181 rons responded to ST stimulation with either all-or-none or graded amplitude EPSCs.

182 hreshold depolarizations that occurred in an all-or-none or graded manner, due to recruitment of T-ty

183 whether one is dealing with a dichotomous ("all-or-none") or a gradual phenomenon.

184 compliance accounting for total compliance (all or none) or for partial compliance ("dose" or number

185 trength of individual synapses in a digital (all-or-none) or analog (graded) manner.

186 kinetochore substrates are completely (i.e., all-or-none) or only fractionally phosphorylated.

187 Thus, MBNL1 loss does not have an all or none outcome but rather shows a graded effect on

188 tems to convert graded inputs into decisive, all-or-none outputs.

189 onverting graded input signals into discrete all-or-none outputs.

190 function of postsynaptic receptors, and are all-or-none overshooting events, rather than graded pote

191 Here we show that there is a striking all or none pattern for CTL escape mutations in HIV-1 Ga

192 karyotic cellular mRNAs generally follow an 'all-or-none' pattern.

193 ar function, beyond eliciting the well known all-or-none PC complex spike.

194 t may be achieved by mixing a graded with an all-or-none permeabilizer.

195 fast-onset depolarization but also a delayed all-or-none persistent depolarization, lasting up to 1 s

196 on, and suggest they should be viewed not as all-or-none phenomena, but as a continuing series of bio

197 and joining (J) recombination is not just an all or none phenomenon.

198 sociated with durable LVAD support is not an all-or-none phenomenon and manifests in a continuous spe

199 The simulation results show that the all-or-none phenomenon is governed largely by random cel

200 g modulatory effect but is necessary for the all-or-none phenomenon of BK channel modulation by the g

201 formation of each hypersensitive site was an all-or-none phenomenon.

202 iod of hours, the release of proteins is an "all or none" phenomenon that is completed in an individu

203 lar processes, was developed to examine the "all-or-none" phenomenon observed in autocatalytic system

204 Therefore peristalsis is not necessarily an "all-or-none" phenomenon.

205 coefficient of 12 and resembles an apparent 'all-or-none' phenomenon.

206 laboratory observations, including certain 'all-or-none' phenotypes and complex differentiation patt

207 the ulnar nerve at the elbow, and recording all-or-none potentials from flexor carpi ulnaris.

208 Individual synapses appear to have all-or-none potentiation indicative of highly cooperativ

209 lly translates only strong Ca2+ signals into all-or-none potentiation of individual hippocampal synap

210 maternally imprinted gene, occurs through an all-or-none process leading to a mixture of fully imprin

211 tive-feedback loop, which contributes to the all-or-none process of oocyte maturation.

212 tes that the inactivation of POD by PL is an all-or-none process related to loss of helical structure

213 of small proteins has been assumed to be an all-or-none process that involves high cooperativity wit

214 protein structures are assumed to fold in an all-or-none process that is inaccessible to experiment.

215 n of polygalacturonase by pulsed light is an all-or-none process where disulfide bridges are broken a

216 nt with our hypothesis that LOI occurs by an all-or-none process.

217 data for Naf-BBL remain consistent with the all-or-none process.

218 ) plane shows that the hairpin unfolds by an all-or-none process.

219 -induced leakage of liposome contents was an all-or-none process.

220 ition from prepore to pore appears to be an "all or none" process; partial insertion of the transmemb

221 The all-or-none properties of spike generation and active me

222 es occur randomly in space and time, exhibit all-or-none properties, and provide a vital source of su

223 hemosensitivity has often been considered an all-or-none property.

224 This all-or-none reaction may serve as a switch that determin

225 activity to mild pain may contribute to the "all-or-none" reaction to stressful situations often obse

226 rization and action selection, leading to an all-or-none reconfiguration of sensory-motor mapping.

227 y, the adaptation of glutamate terminals was all-or-none; recycling vesicle pool size at remaining ac

228 nput and under certain conditions even evoke all-or-none regenerative potentials.

229 quency of quantal events, consistent with an all-or-none regulation (up or down) of clusters of alpha

230 partial release from a continuous pool or an all-or-none release from a compartmentalized pool.

231 The mechanism of the all-or-none release of the contents of phospholipid vesi

232 hatidylglycerol (POPG) bilayers that lead to all-or-none release of vesicle contents.

233 rea stress; they are the "none" component of all-or-none release.

234 discrimination by FEF visual cells shows an all-or-none reliance on the presence of stimulus attribu

235 adine, verapamil, and pinacidil each induced all-or-none repolarization at some epicardial sites but

236 tified nonlinear signaling that organizes an all or none response during particle ingestion.

237 ed with IgG density, later signals showed an all or none response, which was regulated by the concent

238 the inferior olive, which evokes a powerful all-or-none response denoted as the complex spike.

239 feedback loop whose potential to generate an all-or-none response in single cells has been a paradigm

240 l evidence points to a graded rather than an all-or-none response in the natural lactose uptake syste

241 ranulation remained unchanged, suggesting an all-or-none response of mast cells after FcepsilonRI tri

242 f a metabotropic glutamate component, and an all-or-none response pattern, which are all signatures o

243 size, a mechanism to read the signal, and an all-or-none response triggered only when the signal reac

244 Lung edema forms (possibly as an all-or-none response) depending not only on global strai

245 This process appears also to follow an all-or-none response, as the vast majority of the crown

246 sensitivity, the phenomenon equivalent to an all-or-none response, in dissociated neural precursor ce

247 sifications imply that treatment leads to an all-or-none response, with potentially important clinica

248 n cell cultures, ERK1/2 activation is not an all-or-none response.

249 nregulated enzymes into a sharp, effectively all-or-none response.

250 gated several alternative mechanisms for the all-or-none response: (1) the univesicular release const

251 for OspC production, spirochetes display an "all or none" response, with some cells displaying high l

252 results suggest that, rather than triggering all or none responses, EGFR coordinates partially indepe

253 Here we show that all-or-none responses can be generated at a transcriptio

254 apical dendrites generated cadmium-sensitive all-or-none responses that were subthreshold for somatic

255 scade in Xenopus oocytes exhibits sustained, all-or-none responses to graded, transient stimuli.

256 Calcium transients produced by all-or-none responses were not restricted to the sites o

257 A responses included synaptic depression and all-or-none responses, while Class 1B responses exhibite

258 ch determine the effective thresholds of the all-or-none responses.

259 titration") can generate ultrasensitive or "all-or-none" responses that are equivalent to highly coo

260 cetylglucosamine, N-acetylneuraminic acid), 'all-or-none' responses (d-xylose, l-rhamnose) and comple

261 e annihilation of oppositely directed waves, all-or-none responsiveness, and refractoriness.

262 However, at higher field strengths this all-or-none sensitivity reverts to a more gradual transi

263 the view that the climbing fiber conveys an all-or-none signal to the cerebellar cortex and help to

264 are tuned for synapse development versus the all-or-none signalling required for high-fidelity skelet

265 synapses where the presynaptic signal is an all-or-none spike, the probabilistic manner of neurotran

266 a continuously graded membrane potential to all-or-none spikes.

267 Previous work has shown that the all-or-none spiking behavior of neurons can be mimicked

268 extended activation domain to guarantee the 'all or none' splicing switch that is required during Dro

269 p and wakefulness are not simple, homogenous all-or-none states but represent a spectrum of substates

270 An all-or-none step led to final release of ESCRT-III and V

271 A direct consequence of mode-switching is all-or-none stochastic fluctuations in the electrochemic

272 Each release event is all-or-none, stochastic and can impact multiple neurons

273 The distribution of isoforms was mostly all or none, suggesting on/off switching as a frequent m

274 ity and changed its leakage mechanism toward all-or-none, suggesting more specific, larger, and/or lo

275 Simulations further indicated an all-or-none switch to HA-mac at threshold levels of HbHp

276 that, in addition to the generally observed all-or-none switch, the basal transcription machinery al

277 Furthermore at some all-or-none synapses, changes of averaged response ampli

278 ected if the protein is a truly cooperative, all-or-none system.

279 Rather than being all-or-none, telomere deprotection would thus proceed fi

280 er to a triple helix is best described by an all-or-none third-order reaction.

281 tion gradients of extracellular factors into all-or-none threshold responses leading to discrete patt

282 to be maintained, changed dramatically from all-or-none to graded in the mutants of cecropin and mag

283 operate in different functional regimes: the all-or-none toggle or the linear filter mode, depending

284 All-or-none total bundle compliance increased from 4.9-7

285 le-negative feedback loop, ensuring a robust all-or-none transition for Clb5/6-Cdk1 activity.

286 H are in excellent agreement, indicating an all-or-none transition for this triplex.

287 ard- and inward-facing forms, rather than an all-or-none transition of the three subunits, a mechanis

288 ions of a chemical denaturant, preceding the all-or-none transition to the unfolded state.

289 though global folding can be described as an all-or-none transition.

290 end, the folding and unfolding appears as an all-or-none transition.

291 on of the knob-hole interactions was not an "all-or-none" transition as it occurred through distinct

292 Fully cooperative all-or-none transitions are obtained for arrays with eno

293 Here we characterize step-like all-or-none transitions from baseline synaptic transmiss

294 ows both the N- and C-domain to fold through all-or-none transitions with similar refolding rates.

295 on response region RNA hairpin unfolds in an all-or-none two-state reaction at any loading rate with

296 To date, human studies have demonstrated an "all-or-none" type of control for a fixed number of pre-d

297 and L19P) resulted in sawtooth patterns with all-or-none unfolding events that elongated the molecule

298 beta-strand, produced sawtooth patterns with all-or-none unfolding events that lengthened the molecul

299 tely reproduced by the simple kinetics of an all-or-none unfolding process.

300 e response test, phase shifts appeared to be all-or-none with threshold irradiance between 140 and 10