ライフサイエンスコーパス: allantoin

1 a mechanism similar to the isomerization of allantoin.

2 rate and 5-hydroxyisourate, which decayed to allantoin.

3 functional UOx catalyzes urate oxidation to allantoin.

4 solution and decay nonstereospecifically to allantoin.

5 arboxylase in unliganded form and with bound allantoin.

6 ated roots supplied with ammonium nitrate or allantoin.

7 esponsible for the anaerobic assimilation of allantoin.

8 o a 5 times increased urine soluble product, allantoin.

9 nized enzymatic pathway for the formation of allantoin.

10 mans, metabolize uric acid a step further to allantoin.

11 Exogenous application of allantoin (10 uM) provides salt-tolerance to salt-sensit

12 creatinine, ascorbate, 2-hydroxyisobutyrate, allantoin, 4-DEA, 4-hydroxyphenylacetate).

13 drolytic cleavage of the five-member ring of allantoin (5-ureidohydantoin) to form allantoic acid.

14 Allantoin, a marker of oxygen free radical generation, d

15 Allantoin, a metabolite generated in the purine degradat

16 Allantoinase hydrolyzes allantoin, a purine metabolite and a nitrogen transport

17 ss-inducible mutants for AtALN revealed that allantoin accumulation is essential for salt stress tole

18 e potential regulatory role of this gene for allantoin accumulation, AtALN promoter activity was stud

19 -containing metabolites in their sap, namely allantoin, allantoic acid, hydroxymethylglutamate, and m

20 ntoinase, an enzyme that is specific for (S)-allantoin, an allantoin racemase is necessary for comple

21 ia is finally reduced in uninfected cells to allantoin and allantoic acid [1].

22 More specifically, tropical legumes utilize allantoin and allantoic acid as major nodule-to-shoot ni

23 Transport of allantoin and allantoic acid out of nodules requires the

24 _003516366) and GmUPS1-2 (XP_003518768) - in allantoin and allantoic acid transport out of the nodule

25 itrogen is used for synthesis of the ureides allantoin and allantoic acid, the major long-distance tr

26 an, the products of fixation are the ureides allantoin and allantoic acid, which are also the dominan

27 (+)/K(+) ratio, MDA, soluble sugar, proline, allantoin and chlorophyll contents were also associated

28 e oxidase (UOX), which oxidizes uric acid to allantoin and in the process generates H2O2, was introdu

29 Allantoin and its degradation derivatives are a group of

30 Cl at different concentrations showed higher allantoin and lower allantoic acid contents.

31 ocket that interacts with the ureido tail of allantoin and serves to control the orientation of the h

32 uctures of C79S/C184S KpHpxA in complex with allantoin and with 5-acetylhydantoin are presented.

33 f Rasburicase, the urinary excretion rate of allantoin, and antibodies to Rasburicase were also studi

34 samine, hydroxyproline and the anti-oxidants allantoin, anserine, cysteamine, spermine, and squalene

35 Many plants, fungi, and bacteria catabolize allantoin as a mechanism for nitrogen assimilation.

36 Possible roles of allantoin as a protectant compound in oxidative events o

37 strated the role of exogenous application of allantoin as well as increased concentration of endogeno

38 Further, the key gene of allantoin biosynthesis pathway i.e., urate oxidase of th

39 yeast mutant showing that PvUPS1 transports allantoin but also binds its precursors xanthine and uri

40 d some bacteria the product of hydrolysis of allantoin by allantoinase is the unstable intermediate u

41 rate (HIU), which is further degraded to (S)-allantoin by two enzymes, HIU hydrolase and 2-oxo-4-hydr

42 ribed enzymes involved in urate oxidation to allantoin, catalyzed by a flavoprotein monooxygenase (Hp

43 In other species, an increase in allantoin content was observed under different stress co

44 oprotein monooxygenase (HpxO enzyme), and in allantoin conversion to allantoate, which involves allan

45 s conditions UPS5L and UPS5S may function in allantoin degradation for nutrient recycling, whereas un

46 onstrate that these enzymes are required for allantoin degradation in vivo.

47 ates that they could have different roles in allantoin distribution between subcellular compartments.

48 ), the mechanism and molecular components of allantoin export from root cells are still unknown.

49 ings depicted the functional conservation of allantoin for salinity tolerance in both plant clades.

50 mutant is impaired in its ability to utilize allantoin, gamma-aminobutyrate, isoleucine, nitrate, ure

51 In addition, nonenzymatic racemization of allantoin has been shown to occur at physiological pH.

52 tation of a yeast mutant (dal1) deficient in allantoin hydrolysis.

53 ell as increased concentration of endogenous allantoin in rendering salinity tolerance in rice and Ar

54 talyze the complete hydrolysis of the ureide allantoin in vitro.

55 The urinary excretion rate of allantoin increased during Rasburicase treatment, peakin

56 However, the detail mechanism of allantoin involvement in salinity stress tolerance in pl

57 Allantoin is a purine oxidative product involved in long

58 Since the further breakdown of allantoin is catalyzed by allantoinase, an enzyme that i

59 interconvert the (R)- and (S)-enantiomers of allantoin is demonstrated, and analysis of the steady-st

60 Although, allantoin is known to be involved in nitrogen metabolism

61 Although it has been determined that allantoin is mostly synthesized in roots and transported

62 oin synthesis and degradation indicates that allantoin is produced in peroxisomes and degraded in the

63 that catalyzes conversion of uric acid into allantoin, is showing promise with its ability to rapidl

64 Allantoin levels measured in control samples were compar

65 egression analysis revealed that high plasma allantoin levels, including allantoin-to-uric acid ratio

66 en limitations including ammonium, urea, and allantoin limitation.

67 nd BR biosynthesis pathways were involved in allantoin mediated salinity tolerance in both rice and A

68 phyll contents were also associated with the allantoin-mediated salinity tolerance in urate oxidase o

69 to investigate the effects of salt stress on allantoin metabolism and to know whether its accumulatio

70 of a larger metabolic context of purine and allantoin metabolism.

71 regions spanning the deletions involving the allantoin operon and the fljAB operon were PCR amplified

72 ese genes in mosquitoes was shown by feeding allantoin or allantoic acid, which significantly increas

73 of these genes is induced in the presence of allantoin or its degradative metabolites and repressed w

74 NH4Cl, [5-(15)N]-glutamine, [(15)N]-proline, allantoin, or allantoic acid.

75 olism of small molecules, e.g., amino acids, allantoin, or ammonia.

76 Allantoin pathway gene expression in Saccharomyces cerev

77 es and trans-acting factors are required for allantoin pathway gene transcription as follows: (i) UAS

78 conclusions has employed inducer-independent allantoin pathway genes (e.g. DAL5 and DAL3).

79 these elements and their roles to inducible allantoin pathway genes using the DAL7 (encoding malate

80 ium containing [(14)C]adenine, which implies allantoin production.

81 oin conversion to allantoate, which involves allantoin racemase (HpxA enzyme).

82 e characterize the structure and activity of allantoin racemase from Klebsiella pneumoniae (KpHpxA).

83 nzyme that is specific for (S)-allantoin, an allantoin racemase is necessary for complete and efficie

84 resented a susceptible phenotype and altered allantoin root-to-shoot content ratios.

85 llular localization of enzymes that catalyze allantoin synthesis and degradation indicates that allan

86 favored the expression of genes involved in allantoin synthesis, but strongly repressed the unique g

87 Allantoin, the predominant product of free radical-induc

88 In Arabidopsis, the addition of allantoin to the medium as a sole source of nitrogen res

89 n nodules, PvUPS1 is involved in delivery of allantoin to the vascular bundle and loading into the no

90 that high plasma allantoin levels, including allantoin-to-uric acid ratio and high xanthine-to-hypoxa

91 may be involved in vesicular export allowing allantoin translocation from roots to shoots.

92 In addition, the possible role of allantoin transport was investigated.

93 ean and was functionally characterized in an allantoin transport-deficient yeast mutant showing that

94 A putative allantoin transporter (PvUPS1) was isolated from nodulat

95 omic data after exogenous supplementation of allantoin under salinity stress showed induction of ABA

96 loped a rapid and specific assay for urinary allantoin using ultra-performance liquid chromatography-

97 Allantoin was present in human saliva and associated wit

98 ic oxidative degradation of uric acid to (S)-allantoin was recently shown to proceed via three enzyma

99 Allantoin was significantly reduced and 3-methylhistidin

100 ne, and nucleotide catabolism products (e.g. allantoin) were more abundant in the dry states, suggest

101 he zinc enzyme utilizes only the S isomer of allantoin, whereas the cobalt allantoinase prefers the S

102 s, uricase (urate oxidase) converts urate to allantoin, which is more soluble in urine than uric acid

103 ) is a transmembrane protein that transports allantoin with high affinity when expressed in yeast.