ライフサイエンスコーパス: allergic sensitization

1 and SE sensitization to allergic disease and allergic sensitization.

2 This effect was independent of allergic sensitization.

3 5% CI: 1.21-37.74), but not among those with allergic sensitization.

4 ed TH2 inflammation but does not prevent the allergic sensitization.

5 gate the possible association with childhood allergic sensitization.

6 elopment of recurrent wheezing illnesses and allergic sensitization.

7 sm, but is largely unexplored in relation to allergic sensitization.

8 ggered by distinct types of adjuvants during allergic sensitization.

9 ciation with childhood allergic rhinitis and allergic sensitization.

10 lative to skin transepidermal water loss and allergic sensitization.

11 nfections, asthma exacerbations, eczema, and allergic sensitization.

12 fraction of exhaled nitric oxide (Feno), and allergic sensitization.

13 articipated in a mouse model of NO2-promoted allergic sensitization.

14 ntation and asthma exacerbations, eczema, or allergic sensitization.

15 thought to be crucial for the development of allergic sensitization.

16 re of B cells to pollen constituents affects allergic sensitization.

17 that PAR2 activation in the airways leads to allergic sensitization.

18 mportant tools for the clinician to diagnose allergic sensitization.

19 to control oxidative stress might prime for allergic sensitization.

20 from Rhizopus oryzae, an indoor mold causing allergic sensitization.

21 concurrent with antigen exposure accelerated allergic sensitization.

22 initiators of atopic dermatitis and possibly allergic sensitization.

23 ted by commensal bacteria to protect against allergic sensitization.

24 at may lead to increased clinically relevant allergic sensitization.

25 ons with self-reported allergic rhinitis and allergic sensitization.

26 re least likely to have recurrent wheeze and allergic sensitization.

27 ion was not found between TSLP and eczema or allergic sensitization.

28 hinitis from 10 to 16 years, stratifying for allergic sensitization.

29 to be important especially in patients with allergic sensitization.

30 n the quantity of LPS inhaled at the time of allergic sensitization.

31 t of allergen exposure on the development of allergic sensitization.

32 sive circumstances, mount a Th2 response for allergic sensitization.

33 boratory animals is useful for understanding allergic sensitization.

34 he involvement of Treg in the suppression of allergic sensitization.

35 eding in MCT-based diets, caused spontaneous allergic sensitization.

36 lergen was associated with a greater risk of allergic sensitization.

37 rbons (PAHs), can augment the development of allergic sensitization.

38 es in models of infection, autoimmunity, and allergic sensitization.

39 ctory was associated with the early onset of allergic sensitization.

40 TRPV4, calcium, and calcineurin to initiate allergic sensitization.

41 g examples of research into the mechanism of allergic sensitization.

42 ncreased allergen penetration predisposes to allergic sensitization.

43 influence immune responses in the context of allergic sensitization.

44 rgies without inducing allergic reactions or allergic sensitization.

45 al for inducing inflammation of the lung and allergic sensitization.

46 ty among children with frequent wheezing and allergic sensitization.

47 espect to the direction of associations with allergic sensitization.

48 ndotoxin and the effect of this endotoxin on allergic sensitization.

49 nderstanding of the immune mechanisms behind allergic sensitization.

50 th age-specific association between DNAm and allergic sensitization.

51 ation (DNAm) at some CpGs is associated with allergic sensitization.

52 ence of LPS on mugwort pollen was needed for allergic sensitization.

53 gands, but not proteases, induced TNF during allergic sensitization.

54 n was evaluated in a murine model of Phl p 5 allergic sensitization.

55 pe of enhanced eosinophilic inflammation and allergic sensitization.

56 (95% CI: 1.02, 1.33), 1.20 for any specific allergic sensitization (95% CI: 1.05, 1.37), and 1.43 fo

57 5% CI: 1.05, 1.37), and 1.43 for tree pollen allergic sensitization (95% CI: 1.19, 1.72).

58 fic immune deviation than via suppression of allergic sensitization, a mechanism to be considered in

59 Allergic sensitization against 28 inhalant and food alle

60 Allergic sensitization against common inhalant and food

61 e- and postadolescence genome-wide DNAm with allergic sensitization against indoor, outdoor and food

62 Early allergic sensitization (aHR, 4.53; 95% CI, 3.25-6.32), e

63 re noted on the effect of a viral infection, allergic sensitization, airway inflammation and airway h

64 Early onset of asthma was associated with allergic sensitization among adults with asthma.

65 The prevalence of allergic sensitization among patients with asthma decrea

66 tion, inflammatory chemokine production, and allergic sensitization and airway inflammation suggest t

67 RWPE induced MD2-dependent allergic sensitization and airway inflammation.

68 ilic inflammation, which in turn facilitates allergic sensitization and airway inflammation.

69 and IL-13 antagonist IL-4 mutein (IL-4M) on allergic sensitization and AIT outcome in experimental a

70 ocation of Treg cell function differs during allergic sensitization and allergen-induced recall respo

71 mouse model of house dust mite (HDM)-induced allergic sensitization and allergic airway inflammation.

72 among the most common allergens that induce allergic sensitization and allergic diseases.

73 k and mature milk and to investigate whether allergic sensitization and an anthroposophic lifestyle c

74 everity are an allergy pathway starting with allergic sensitization and an environmental tobacco smok

75 Dietary MCTs promote allergic sensitization and anaphylaxis by affecting anti

76 mice, only treatments with holoBLG prevented allergic sensitization and anaphylaxis, while sustaining

77 ogic data describing the association between allergic sensitization and asthma and allergic rhinitis

78 or development of atopic dermatitis; data on allergic sensitization and asthma were collected when ch

79 en associated with subsequent development of allergic sensitization and asthma.

80 hanisms regarding cockroach allergen-induced allergic sensitization and asthma.

81 nt of immune function, and predisposition to allergic sensitization and asthma.

82 that influence the development of childhood allergic sensitization and atopic diseases.

83 Although biomarkers, such as allergic sensitization and blood eosinophilia, might be

84 In addition, allergic sensitization and blood eosinophils can be used

85 llular interactions that are associated with allergic sensitization and clinical food allergy in the

86 The immune states that predispose towards allergic sensitization and disease development remain il

87 tective role of breastfeeding in relation to allergic sensitization and disease.

88 years of life have been linked with risk of allergic sensitization and disease.

89 sponse, thereby predisposing the organism to allergic sensitization and disrupting immune tolerance i

90 ed with enhanced primary immune responses to allergic sensitization and elevated production of multip

91 SLP) and 2p23 (CAPN14), indicating roles for allergic sensitization and esophageal specific protease

92 , sociodemographic, and regional patterns of allergic sensitization and examined risk factors associa

93 Allergic sensitization and filaggrin gene (FLG) variants

94 on of allergic comorbidities associated with allergic sensitization and FLG variants emphasize their

95 tence of allergic disorders is frequent, and allergic sensitization and FLG variants jointly increase

96 stigating the single and combined effects of allergic sensitization and FLG variants on the developme

97 Associations of allergic sensitization and FLG variants with single and

98 In repeated measurement analyses, allergic sensitization and FLG variants, when analysed s

99 At age 10 years, inhalant allergic sensitization and food-allergic sensitization w

100 esting, only the associations of GIMAP4 with allergic sensitization and GIMAP5 with asthma remained s

101 rough the oral route may contribute to child allergic sensitization and have important implications f

102 sequence, PAG1 deficiency predisposed toward allergic sensitization and increased the severity of exp

103 s and whether this induction could determine allergic sensitization and inflammation.

104 tions between prenatal exposures to POPs and allergic sensitization and lung function in 20-year-old

105 e cells and skin cells and protected against allergic sensitization and lung inflammation through the

106 he impact of an epithelial barrier defect on allergic sensitization and mast cell (MC) degranulation

107 nted allergic diseases in mice by increasing allergic sensitization and memory immune responses.

108 gens and endotoxin and to the development of allergic sensitization and recurrent wheeze assessed at

109 imuli are associated with the development of allergic sensitization and recurrent wheeze.

110 elationship between plasma levels of TSLP to allergic sensitization and recurrent wheezing was conduc

111 The association between allergic sensitization and rhinitis was consistently str

112 ish introduction was associated with reduced allergic sensitization and rhinitis.

113 f DNA-PK in DCs, attenuates the induction of allergic sensitization and Th2 immunity via a mechanism

114 ith FcepsilonRI is primarily responsible for allergic sensitization and the inflammatory response, wh

115 Therefore, because both allergic sensitization and viral and bacterial illnesses

116 of investigators include the development of allergic sensitization and wheezing respiratory tract il

117 acilitates transepithelial allergen passage, allergic sensitization, and allergen-induced MC degranul

118 iated with development of atopic dermatitis, allergic sensitization, and asthma.

119 llergenic trees, discuss factors pivotal for allergic sensitization, and describe the role of tree po

120 perimental model of atopic dermatitis, TEWL, allergic sensitization, and epidermal thickness were inc

121 Patterns of wheezing, allergic sensitization, and lung function identified fiv

122 rhinitis appears less likely to be driven by allergic sensitization, and may imply disease onset in u

123 vented chitosan-induced barrier dysfunction, allergic sensitization, and MC degranulation.

124 models identified trajectories of wheezing, allergic sensitization, and pulmonary function.

125 e over the first 3 years was associated with allergic sensitization, and sensitization at age 3 years

126 with current rhinitis among children without allergic sensitization (AOR = 6.76; 95% CI: 1.21-37.74),

127 n-based studies about the natural history of allergic sensitization are rare.

128 IgA(+) B-cell numbers in children with food-allergic sensitization are suggestive of TGF-beta-mediat

129 Multiple allergic sensitizations are common in persistent childho

130 ion on atopic dermatitis, inhalant- and food-allergic sensitization, asthma lung function scores was

131 Associations between allergic sensitization, asthma, and eczema were estimate

132 ed with respect to lung function outcomes or allergic sensitization at 18 to 19 years of age.

133 e associated with airway obstruction but not allergic sensitization at 20 years of age.

134 aternal concentrations of POPs and offspring allergic sensitization at 20 years of age.

135 and in cord blood seemed to protect against allergic sensitization at 5 years of age.

136 two methods for diagnosing inhalant and food allergic sensitization at the four age points was analyz

137 we identified 35 CpGs in IoW associated with allergic sensitization (at false discovery rate of 0.05)

138 Here we analyze the skin microbiota, allergic sensitization (atopy), and immune function in a

139 lies and in a prospective Swedish asthma and allergic sensitization birth cohort.

140 that BCG vaccination did not protect against allergic sensitization but might have exerted a protecti

141 arly life plays a role in the development of allergic sensitization but not in the development of res

142 f genetic variants have been associated with allergic sensitization, but whether these are allergen s

143 The increasing prevalence of allergic sensitization by age was explained by high inci

144 relationship between helminth infection and allergic sensitization by assessing the influence of pre

145 effects of triclosan or paraben exposure on allergic sensitization by sex observed in this study war

146 ent asthma and rhinitis), puberty status and allergic sensitization by specific serum antibodies (imm

147 rolled (n = 31) asthmatics were assessed for allergic sensitization by two microarray systems (Microt

148 Although allergic sensitization can be generated against various

149 Taken together, our data suggest that allergic sensitization coincident with filarial infectio

150 ure to TRAP in middle age is associated with allergic sensitization, current asthma, and reduced lung

151 Allergic sensitization decreased with increasing age, bo

152 mokers with COPD (n = 77) were evaluated for allergic sensitization defined as a detectable specific

153 ided by IgE reporter cells, creating a novel allergic sensitization detection system.

154 Interestingly, IL-4Ralpha knockdown after allergic sensitization did not induce T(H) 17, a neutrop

155 The overall prevalence of allergic sensitization does not vary across US census re

156 Our data suggest that HDM allergic sensitization drives a response that mimics a p

157 wed by Ascaris infection to demonstrate that allergic sensitization drives an eosinophil-rich pulmona

158 intestinal microbiota and the development of allergic sensitization, eczema, and asthma in neonates a

159 laceae is associated with the development of allergic sensitization, eczema, or asthma.

160 h cohort we investigated whether concomitant allergic sensitization enhances subsequent development o

161 luding a high degree of comorbid conditions, allergic sensitization, exacerbations, and very poorly c

162 cts with filarial infections, and coincident allergic sensitization (filarial [Fil](+)allergy [A](+))

163 atients' demographic and historical factors, allergic sensitization, fraction of exhaled nitric oxide

164 ne learning approach to longitudinal data on allergic sensitization from two independent unselected b

165 onversely, persistence is linked strongly to allergic sensitization, greater frequency and severity o

166 with atopic dermatitis, inhalant-, and food-allergic sensitization had higher memory Treg cell numbe

167 Children with food-allergic sensitization had higher total B and CD27(+) Ig

168 Atopic dermatitis and allergic sensitization had significant interactions on b

169 In combination, atopic dermatitis and allergic sensitization had strong interactive effects on

170 The presence of allergic sensitization has a major influence on the deve

171 Molecule-based profiling of allergic sensitization has helped to elucidate the immun

172 f hay fever, eczema and objective markers of allergic sensitization have been found fairly consistent

173 oms, but associations with lung function and allergic sensitization have been minimally explored.

174 development of diisocyanate (dNCO)-specific allergic sensitization; however, MDI-haptenated albumins

175 oes not seem to increase the overall risk of allergic sensitization; however, sensitization to birch

176 et v 1-specific CD4(+) T cells and prevented allergic sensitization in a mouse allergy model.

177 ted fatty acids (n-3 LCPUFA) largely prevent allergic sensitization in a murine model for cow's milk

178 In a cohort of pregnant women patterns of allergic sensitization in adulthood were not found to di

179 thyl phthalate was inversely associated with allergic sensitization in adults (OR = 0.79; 95% CI: 0.7

180 , airway epithelial NF-kB activation induced allergic sensitization in CAIKKbeta mice on Dox that req

181 posure is associated with the development of allergic sensitization in childhood as reflected by glob

182 S exposure contributes to the development of allergic sensitization in children and adolescents up to

183 smoke (SHS) exposure and the development of allergic sensitization in children is unclear.

184 en air pollution exposure and development of allergic sensitization in children up to 10 years of age

185 oncurrent asthma, altered lung function, and allergic sensitization in children.

186 sly showed that the ability of HDM to induce allergic sensitization in mice is related to airway epit

187 hosphate (ATP)-dependent Ca(2+) signaling in allergic sensitization in mice, we sought to determine t

188 We compared allergic sensitization in patients with food allergy or

189 Elevated hs-CRP is associated with allergic sensitization in school-aged children suggestin

190 s and childhood asthma, recurrent wheeze, or allergic sensitization in the overall study population.

191 The development of specific allergic sensitization in the skin of those patients fol

192 ve interaction between atopic dermatitis and allergic sensitization in their effects on food allergy

193 greement between SPT and sIgE for diagnosing allergic sensitization in young children, which increase

194 However, the molecular mechanisms of birch allergic sensitization, including the roles of Bet v 1 a

195 Conversely, atopic dermatitis with allergic sensitization increased the risk of asthma more

196 atures with the exception of some markers of allergic sensitization, indicating a need to develop bet

197 d pollen-intrinsic NADPH oxidase activity in allergic sensitization, inflammation, and airway hyperre

198 associations of breastfeeding with childhood allergic sensitization, inhalant or food allergy and ecz

199 he link between skin barrier dysfunction and allergic sensitization initiating the atopic march.

200 peutic supplement for those AD patients with allergic sensitization interferes with IgE-mediated infl

201 Allergic sensitization is a multifactorial process that

202 Allergic sensitization is a particularly difficult proce

203 Allergic sensitization is an important risk factor for t

204 hanism underlying clinical observations that allergic sensitization is associated with increased susc

205 Allergic sensitization is associated with poor clinical

206 Allergic sensitization is associated with severe asthma,

207 is widely distributed in homes and schools; allergic sensitization is common.

208 erm exposure air to pollution has effects on allergic sensitization is controversial.

209 Allergic sensitization is initiated by allergen-specific

210 hibitory effect of uricase administration on allergic sensitization is mediated more through Ag-speci

211 The etiology of allergic sensitization is poorly understood, and its und

212 sensitization on allergic multimorbidity and allergic sensitization is unclear.

213 ous metabolite 9-cis retinoic acid (9cRA) on allergic sensitization is unknown.

214 microbiome of infants who went on to develop allergic sensitization later in childhood lacked genes e

215 s a critical role in the induction of peanut-allergic sensitization, likely due to its ability to act

216 y differentiated by patterns of wheezing and allergic sensitization (low wheeze/low atopy; low wheeze

217 Associations between TRAP exposure and allergic sensitization, lung function, current wheeze, a

218 between HM TGF-beta and risk of eczema; 14, allergic sensitization; nine, wheezing/asthma; six, food

219 Allergic sensitization occurs at high frequency in patie

220 5571 was associated with risk for asthma and allergic sensitization (odds ratio [OR] 3.74, p = 0.0007

221 somal phenotype was related to lifestyle and allergic sensitization of the mothers, and sensitization

222 disease and children with inhalant- and food-allergic sensitization or atopic dermatitis had higher c

223 ly nonmodifiable factors, particularly early allergic sensitization or eczema and parental AR, predic

224 eak overall increased risk of eczema but not allergic sensitization or physician-diagnosed allergy at

225 osure does not seem to affect development of allergic sensitization or rhinitis during childhood ques

226 ociated with asthma (OR 1.28, p = 0.035) and allergic sensitization (OR 1.27, p = 0.0068).

227 ce interval (CI): 0.61, 0.76; P < 0.001) and allergic sensitization (OR = 0.74, 95% CI: 0.64, 0.86; P

228 I: 0.920, 0.998; P = 0.041), a lower risk of allergic sensitization (OR = 0.92, 95% CI: 0.84, 1.02; P

229 (OR = 1.10 [1.01-1.12], P = 0.033) and with allergic sensitization (OR = 1.10 [1.03-1.17], P = 0.003

230 y fever (OR= 0.998; 95% CI: 0.994, 1.002) or allergic sensitization (OR=0.999; 95% CI: 0.986, 1.012)

231 re at a significantly higher risk developing allergic sensitization(OR [95% CI] = 2.00 [1.04:3.86] at

232 circulating TSLP is associated with eczema, allergic sensitization, or recurrent wheezing in young c

233 ved no association of breastfeeding with any allergic sensitization, physician-diagnosed allergy, or

234 airway disease but may be overcome to induce allergic sensitization preceding the development of asth

235 curred at Hokkaido University, we studied on allergic sensitization prevalence for laboratory animals

236 of the present study was to investigate the allergic sensitization profile in asthmatics and examine

237 The processes involved in the genesis of allergic sensitization remain elusive.

238 icance of the observed differences for later allergic sensitization remains open.

239 birth to age 10 years and susceptibility to allergic sensitization, respiratory tract infections, an

240 inical examination including measurements of allergic sensitization (serum-specific IgE >/= 0.35 kUA

241 e causal effect of BMI on asthma, hay fever, allergic sensitization, serum total immunoglobulin E (Ig

242 ed the clusters in two models: age of onset, allergic sensitization, severity, and recent exacerbatio

243 Allergic sensitization showed no association with asthma

244 increased eosinophilic airway inflammation, allergic sensitization, TH2 cytokine production, and muc

245 atios were higher among participants without allergic sensitization than among those with, but intera

246 been used to investigate some mechanisms of allergic sensitization, the generation of humoral immuni

247 ibutor to barrier disruption associated with allergic sensitization, there is a need to better unders

248 interdependency between asthma, eczema, and allergic sensitization through childhood.

249 reasing evidence regarding the importance of allergic sensitization through the skin.

250 The prevalence of allergic sensitization to any aeroallergen was 51% (95%

251 MD2 plays an important role in induction of allergic sensitization to cat dander and common pollens

252 Allergic sensitization to cat, dog, and house dust mites

253 sociation between air pollution exposure and allergic sensitization to common allergens in children f

254 ed OR = 4.4, 95% CI 1.5-13.7 for 2 parents); allergic sensitization to common household aeroallergens

255 ctors include elevated exhaled nitric oxide, allergic sensitization to common household aeroallergens

256 e 25% for high exhaled nitric oxide, 22% for allergic sensitization to common household aeroallergens

257 role of the AD skin phenotype in modulating allergic sensitization to common sensitizers has not bee

258 h2 effector cell differentiation and prevent allergic sensitization to dietary antigens.

259 ion of Th2 effector cell differentiation and allergic sensitization to dietary antigens.

260 Birth cohort studies have shown that allergic sensitization to food allergens develops early

261 n-diagnosed asthma or recurrent wheezing and allergic sensitization to food or environmental antigens

262 ively breastfed children, this suggests that allergic sensitization to foods can be mediated by cutan

263 ation of the immunologic pathways underlying allergic sensitization to foods in humans has been great

264 n essential requisite for the development of allergic sensitization to foods.

265 arrier impairment, and AD also predispose to allergic sensitization to foods.

266 Allergic sensitization to fungi has been associated with

267 ility to modulate the immune response during allergic sensitization to grass pollen allergens.

268 ollen allergens that are thought to initiate allergic sensitization to grass pollen.

269 Allergic sensitization to inhaled antigens is common but

270 Susceptibility to allergic sensitization to mite allergens in mice was hig

271 nd the cytokines IL-5 and IL-13, mediated by allergic sensitization to multiple foods.

272 ss, lung resistance, and TH2 responses after allergic sensitization to ovalbumin.

273 tors critically involved in the induction of allergic sensitization to peanut.

274 h breast milk may prevent instead of priming allergic sensitization to peanut.

275 oxidative stress plays a significant role in allergic sensitization to pollen via the airway mucosa,

276 P, highlighting an important role for SPP in allergic sensitization to short ragweed.

277 ized the main molecular pathways involved in allergic sensitization to subtilisin that potentially co

278 ze, eczema, allergic rhinitis, food allergy, allergic sensitization, type 1 diabetes mellitus, celiac

279 y through modulating susceptibility to early allergic sensitization, upper respiratory tract coloniza

280 erite children, the prevalence of asthma and allergic sensitization was 4 and 6 times as low in the A

281 The role of oxidative stress in allergic sensitization was also investigated in humans.

282 In adolescence, the status of allergic sensitization was associated with DNAm differen

283 The predisposition to allergic sensitization was associated with increased air

284 The allergic sensitization was determined based on skin pric

285 Allergic sensitization was determined by skin prick test

286 gh-affinity IgE Fc receptor (FcepsilonRI) in allergic sensitization was evaluated using Was(-/-) Fcer

287 Atopic dermatitis without allergic sensitization was not associated with an increa

288 Atopic dermatitis without concomitant allergic sensitization was not associated with an increa

289 Allergic sensitization was not significantly associated

290 A high prevalence of allergic sensitization was observed in this cohort.

291 n between triclosan and paraben exposure and allergic sensitization was observed.

292 pic evaluation of allergic rhinitis (AR) and allergic sensitization was performed on 2153 children fr

293 transepidermal water loss and allergic sensitization were assessed.

294 esophageal expression, and multiple loci for allergic sensitization were associated with EoE suscepti

295 bo/control, for treating AE in patients with allergic sensitization were eligible.

296 d reported allergic or autoimmune disease or allergic sensitization were included.

297 rs, inhalant allergic sensitization and food-allergic sensitization were measured by skin prick tests

298 findings will have a major influence on how allergic sensitization will be viewed and studied in the

299 nature of EoE that involves the interplay of allergic sensitization with an EoE-specific, IL-13-induc

300 Abrogation of IL-4Ralpha signaling after allergic sensitization would have significant therapeuti