ライフサイエンスコーパス: allylic

1 s proceed with a wide variety of ketones and allylic 1,1-diboronate reagents, which enables the effic

2 free alcohols using fluoride or silanolate, allylic acetate precursors to 5-membered rings display d

3 is a three-component coupling that joins an allylic acetate, and indole and an organo-B(pin) species

4 ctivity are retained across diverse branched allylic acetates bearing normal alkyl or secondary alkyl

5 The boronate reacts with allylic acetates in the presence of (BINAP)Pd catalysts

6 ations of racemic branched alkyl-substituted allylic acetates using primary or secondary (hetero)arom

7 tic asymmetric fluoroenolate alkylation with allylic acetates.

8 re, we report a mechanistic study of aerobic allylic acetoxylation of allylbenzene with a catalyst sy

9 urst phase, involving rapid formation of the allylic acetoxylation product and formation of the dimer

10 nd of oxidation to convert oleate to a trans allylic alcohol acid.

11 e light-mediated photoredox reaction from an allylic alcohol and iodoacetic acid.

12 reducing reagent gave a very functionalized allylic alcohol derivative in 86% yield.

13 hydes and allenes, providing silyl-protected allylic alcohol derivatives possessing a terminal methyl

14 Using this method, a number of allylic alcohol derivatives were efficiently obtained wi

15 ogical precursor, redox isomerization of the allylic alcohol gave an epimeric mixture of aldehydes, w

16 sfer process in concert with a base-promoted allylic alcohol isomerization.

17 molecular strategy can overcome the inherent allylic alcohol selectivity of the free catalyst, achiev

18 n-coupled electron transfer activation of an allylic alcohol substrate affords an alkoxy radical inte

19 The racemic allylic alcohol substrates can be converted to the enant

20 al beta-alkynyl carbonyl compounds employing allylic alcohol substrates in contrast to more tradition

21 reduction of a prochiral enone to afford an allylic alcohol with high enantioselectivity.

22 (eta(2)-Allylic alcohol)iridium(I) and (eta(3)-allyl)iridium(III

23 t contain a carboxylic acid, an aldehyde, an allylic alcohol, an aryl olefin, an alpha substituent, o

24 ation of Rh(III), and, collectively with the allylic alcohol, in directing cyclopropanation to contro

25 hothiolate complex and afford trisubstituted allylic alcohols and ethers in up to 81% yield and >98%

26 yze the concomitant isomerization of primary allylic alcohols and homoallylboronates into (chiral) al

27 l variations have been performed on both the allylic alcohols and the homoallylboronates.

28 of thiophiles, the sulfenate is trapped, and allylic alcohols are obtained under mild conditions.

29 Allylic alcohols are shown to be highly reactive olefin

30 for C-H allylation of aryl oxazolines using allylic alcohols as the coupling partner.

31 Allylic alcohols can be directly ionized in the presence

32 lar coupling of ortho-(alkynyl)styrenes with allylic alcohols catalyzed by PdCl(2).

33 shed that the isomerization of epoxides into allylic alcohols catalyzed by supported Au nanoparticles

34 ective Markovnikov addition of carbamates to allylic alcohols for the construction of alpha-tertiary

35 ed formal anti-Markovnikov hydroamination of allylic alcohols for the synthesis of chiral gamma-amino

36 formation unravels the unusual reactivity of allylic alcohols in the synthesis of 4-methyleneisochrom

37 zed diastereoselective [2+1] annulation onto allylic alcohols initiated by alkenyl C-H activation of

38 complexes can catalyze the isomerization of allylic alcohols into saturated carbonyl derivatives und

39 molecular hydrofunctionalization of tertiary allylic alcohols is described.

40 s enable the synthesis of either (Z)- or (E)-allylic alcohols regarding the order of introducing coup

41 enantioselective isomerization of secondary allylic alcohols to access ketones with a alpha-tertiary

42 A ferrocenium boronic acid salt activates allylic alcohols to generate transient carbocations that

43 cess, the catalysis allows racemic secondary allylic alcohols to react with various amines, affording

44 ctive arylative semipinacol rearrangement of allylic alcohols using diaryliodonium salts is reported.

45 n allylic substitutions of branched, racemic allylic alcohols with various nucleophiles.

46 strate classes, including 4-pentenoic acids, allylic alcohols, homoallyl amines, and bis-homoallylami

47 ious alpha-branched aldehydes with different allylic alcohols.

48 d by an enantioselective Rh isomerization of allylic alcohols.

49 the development of a Pd-catalyzed asymmetric allylic alkylation (Pd-AAA) of acyclic alpha-hydroxyketo

50 ications in both copper-catalyzed asymmetric allylic alkylation and copper-catalyzed asymmetric boryl

51 This NP-catalyzed electrochemical allylic alkylation expands the synthetic scope of cross-

52 ) is designed for catalyzing electrochemical allylic alkylation in water/isopropanol (1:1 v/v) and 0.

53 duction in the inner-sphere asymmetric Tsuji allylic alkylation is C-C bond formation through a seven

54 talytic cycle for asymmetric decarboxylative allylic alkylation of allyl beta-ketoesters.

55 of a Pd-catalyzed decarboxylative asymmetric allylic alkylation of alpha-nitro allyl esters to afford

56 a challenging palladium-catalyzed asymmetric allylic alkylation of an N-alkyl-alpha,beta-unsaturated

57 Phosferrox (PPh(2)), to palladium catalyzed allylic alkylation of trans-1,3-diphenylallyl acetate re

58 ribe a catalytic, decarboxylative asymmetric allylic alkylation performed on an alpha-silylated subst

59 phosphine ligand facilitate the formation of allylic alkylation products in high branch selectivity.

60 itions for the generation of enantioenriched allylic alkylation products in the presence of catalytic

61 tereo-, and regioselective iridium-catalyzed allylic alkylation reaction of prochiral enolates to for

62 elective palladium-catalyzed decarboxylative allylic alkylation reaction using a novel bisphosphine l

63 al nucleophiles in a Pd-catalyzed asymmetric allylic alkylation reaction, furnishing phosphinates wit

64 imitations of the decarboxylative asymmetric allylic alkylation reaction.

65 st highly enantioselective iridium-catalyzed allylic alkylation that provides access to products bear

66 n, we report a Cu-catalyzed enantioselective allylic alkylation using a gamma-butyrolactone-derived s

67 ne-pot Lewis base/transition-metal catalyzed allylic alkylation/Hofmann rearrangement strategy.

68 Enantioselective Pd-catalyzed allylic alkylations of dihydropyrido[1,2-a]indolone (DHP

69 re studied in palladium-catalyzed asymmetric allylic alkylations, leading to enantioselectivities fro

70 yzed domino carbopalladation/decarboxylative allylic alkynylation of ortho-iodoallenamides with alkyn

71 yl-Pd complex formation, and decarboxylative allylic alkynylation was subsequently set up.

72 that provides access to products bearing an allylic all-carbon quaternary stereogenic center has bee

73 xazole as a vinylogous pronucleophile in the allylic-allylic alkylation of Morita-Baylis-Hillman (MBH

74 (200 mol%) to form the branched products of allylic amination 4a-4l and 5a-5l, respectively, as sing

75 e report the development of a new metal-free allylic amination of alkenes that allows the introductio

76 s undergo alternative oxidative amination or allylic amination pathways, and these reactions will als

77 Here we show the first allylic amination that can directly afford alkyl allylam

78 precedented one-pot successive base-mediated allylic amination/cycloisomerization reaction strategy h

79 iline substrates, with the latter giving the allylic amine as the sole organic product.

80 cal strategy for the synthesis of high-value allylic amine building blocks that does not require the

81 The desired enantiomer of the final allylic amine can be synthesized by choosing the sulfiny

82 relay Heck reaction to give enantioenriched allylic amine products.

83 tereoselective synthesis of a broad range of allylic amines from readily available 1,3-dienes, alkyl

84 The present protocol provides substituted allylic amines in a highly atom- and step-economical man

85 kynes to access alpha,beta,gamma-substituted allylic amines in an atom-economic fashion is reported.

86 ith vinyl bromide electrophiles and delivers allylic amines in excellent yields (up to 99%).

87 d catalyst bearing a PHOX ligand, generating allylic amines in up to 97:3 er.

88 nd provides direct access to valuable chiral allylic amines starting from linear or alpha-branched al

89 Primary allylic amines with enantiomeric excesses from 97 to >99

90 phos ligand, hydroamination generates chiral allylic amines with high regio- and enantioselectivity.

91 lysis to deliver chiral allenes with pendant allylic amines.

92 reveal that the cyclization, followed by 1,3-allylic amino dehydroxylation, is preceded by urea forma

93 precatalyst (FurCat) to promote Pd-catalyzed allylic ammonium salt generation from the allylic phosph

94 yzed enantioselective [2,3]-rearrangement of allylic ammonium ylides is described.

95 catalysts can aminate a variety of benzylic, allylic and aliphatic C-H bonds in excellent enantiosele

96 iron phthalocyanine-catalyzed alkylation of allylic and benzylic C(sp(3))-H bonds.

97 ture was leveraged to enable fluorination of allylic and benzylic C-H bonds and alpha-C-H bonds of et

98 elective functionalization of less activated allylic and benzylic C-H bonds even in the presence of e

99 Allylic and homoallylic alcohols with a variety of funct

100 The preparation of enol and allylic and propargylic alcohol motifs is discussed, hig

101 eactions to unsaturated carbon-carbon bonds, allylic and propargylic nucleophilic substitutions, C-H

102 chemoselective C-H oxygenation of benzylic, allylic, and propargylic C(sp(3) )-H bonds.

103 s a stereoselective cascade reaction between allylic azides and acrylates that directly generates tet

104 n pathway in a dynamic kinetic resolution of allylic azides.

105 Herein is reported the asymmetric allylic benzylation of Morita-Baylis-Hillman (MBH) carbo

106 Regio- and stereoselective distal allylic/benzylic C-H functionalization of allyl and benz

107 diastereo- and enantioselective synthesis of allylic boronates bearing a Z-trisubstituted alkenyl flu

108 rted to undergo mostly 1,4-additions to give allylic boronates.

109 adium-free Stille cross-coupling reaction of allylic bromides and functionalized organostannylfuran u

110 ymmetric alkylation of anthrones with cyclic allylic bromides using quinidine- or quinine-derived cat

111 he lignan scaffold from simple aldehydes and allylic bromides with full control of the two formed ste

112 ation intermediates that conduct to valuable allylic building blocks upon nucleophile attack.

113 a sodium amide has been exploited for formal allylic C(sp(3))-H bond activation of alkenes under mild

114 pai bond with the sigma*(CF) orbitals of the allylic C-F bonds results in the increased preference fo

115 al Pd-catalyzed aerobic oxidation reactions: allylic C-H acetoxylation of terminal alkenes and intram

116 Allylic C-H acetoxylations are among the most widely stu

117 he surface OH density and likely involves an allylic C-H activation mechanism, like the molecular W(I

118 The reaction proceeds through initial allylic C-H activation, supported by the isolation and c

119 t method for intermolecular branch-selective allylic C-H amidation has been accomplished via Ir(III)

120 The Ir(III)-catalyzed direct allylic C-H amidation of substituted internal alkenes wi

121 Allylic C-H amination is currently accomplished with (su

122 A method for catalytic intermolecular allylic C-H amination of trans-disubstituted olefins is

123 (CH) coupling constants of the two competing allylic C-H bonds (Delta(1)J(CH)) and the C-H activation

124 system features chemoselective amination of allylic C-H bonds and is compatible with heteroaryl grou

125 s correlated to the electronic properties of allylic C-H bonds indicated by the corresponding (1)J(CH

126 The oxidative cleavage of benzylic and allylic C-H bonds using DDQ can be coupled with an intra

127 that selectively functionalize benzylic and allylic C-H bonds, affording a broad scope of enantioenr

128 for the functionalization of propargylic and allylic C-H bonds.

129 In contrast, initiation of olefins with allylic C-H groups (e.g., beta-methylstyrene) is indepen

130 sis activity toward olefins with and without allylic C-H groups, namely beta-methylstyrene and styren

131 ployed to effect a chemo- and regioselective allylic C-H oxidation in the presence of four oxidizable

132 t of the regioselective Cp*Ir(III)-catalyzed allylic C-H sulfamidation of allylbenzene derivatives, u

133 ore recently, the catalytic enantioselective allylic carbon-hydrogen oxidation of alkenes has streaml

134 ave been discovered for the enantioselective allylic carbon-hydrogen oxidation of simple alkenes with

135 ctively takes place at the alkyl-substituted allylic carbon.

136 e stapled or cyclized using homobifunctional allylic carbonate reagents.

137 Electron-deficient allylic carbonate was used to generate the highly reacti

138 ion of substituted spiroketals from racemic, allylic carbonates is reported, which enables the instal

139 n of challenging alkyl-substituted secondary allylic carbonates with benzylzinc reagents, which are p

140 he reaction between propargylic alcohols and allylic carbonates, engaging vanadium and palladium cata

141 that increasing the number of deuterated bis-allylic carbons to include both C10 and C13 leads to a m

142 y abstracting hydrogen from one of three bis-allylic carbons within 1,4-cis,cis-diene units.

143 ently catalyzes its alkylation via either an allylic cation or a cationic transition state.

144 the reaction involves an argento-substituted allylic cation.

145 onors and each proceed via cationic species: allylic cations and oxocarbenium ions, respectively.

146 In addition, a bicyclic allylic chloride starting material without pseudo-symmet

147 d are enantioconvergent for pseudo-symmetric allylic chloride starting materials.

148 ransfer from an iridium photocatalyst to the allylic chloride substrate followed by C-Cl homolytic cl

149 ross-coupling between racemic fused bicyclic allylic chlorides and boronic acids.

150 Aryl, aliphatic, and unsubstituted allylic chlorides bearing a broad range of functionality

151 tial diene 1,2-borocupration forms a (3) eta-allylic copper as the most stable intermediate.

152 We show this allylic covalent inhibitor has different catalytic profi

153 s proceed via stereodefined boron-stabilized allylic Cu species formed by an enantioselective transme

154 rrulatane into amphilectane diterpenes by an allylic cyclodehydrogenation coupling.

155 er via regioselective acylation, Tsuji-Trost allylic decarboxylative rearrangement, and aromatization

156 Cu-catalyzed allylic desymmetrizations enable the enantioselective fo

157 o-ene reaction of an allyl diazene, i.e., an allylic diazene rearrangement.

158 ctive transposition of the in situ generated allylic diazene.

159 ective activation of a single C-F bond in an allylic difluoromethylene group to provide a broad range

160 eogenic center with an aliphatic-substituted allylic electrophile is disclosed.

161 functionalized and/or challenging aliphatic allylic electrophiles.

162 where we identified 3 new pathways producing allylic epoxide-derived mediators that stimulate regener

163 onic pi-allyl Pd intermediates, derived from allylic ester carbonates and palladium(0) catalyst, were

164 tions occur with alkyl- and aryl-substituted allylic esters and the unstabilized enolates of azaaryl

165 A borocyclopropanation of (E)- and (Z)-allylic ethers and styrene derivatives via the Simmons-S

166 variety of substituted cinnamic and styrenyl allylic ethyl phosphates.

167 ergo rapid fluoride substitution to generate allylic fluoride products with excellent levels of branc

168 of N-silyl pyrrole latent nucleophiles with allylic fluorides followed by hydrogenation and diastere

169 aldehyde-selective Wacker-type oxidation of allylic fluorides proceeds with a nitrite catalyst.

170 midates to the corresponding enantioenriched allylic fluorides, via a dynamic kinetic asymmetric tran

171 o found that gamma-, beta-, homoallylic, and allylic fluorination are all possible and predictable th

172 Asymmetric allylic fluorination has proven to be a robust and effic

173 ridium-catalyzed regio- and enantioselective allylic fluorination.

174 heteroatom stabilization of the intermediate allylic free radical two sites for oxidative product for

175 was prepared in 6 steps from geraniol using allylic functionalization and alkyne synthesis.

176 Allylic functionalization provides a direct path to chir

177 Transition metal-catalysed allylic functionalization reactions have been establishe

178 Transition metal-catalysed allylic functionalization reactions involving radicals a

179 nal alkenes to be selectively converted into allylic functionalized products with high stereoselectiv

180 avoiding generation of any waste, to produce allylic functionalized structures.

181 l that the azomethine ylide stabilized by an allylic group cycloadds to [60]fullerene in an efficient

182 face-selective reaction of the olefin of the allylic group, leading to a highly diastereoselective fo

183 ing imines, which in turn are susceptible to allylic H-abstraction and further beta-fragmentation lea

184 of alkylzirconocene nucleophiles to racemic allylic halide electrophiles were conducted using a comb

185 elective cross-coupling of alkyl halides and allylic halides to form C-C hydrocarbons with product yi

186 ot observed, while introduction of a second, allylic heteroatom to the substrate results in diminishm

187 turation of aliphatic alcohols into valuable allylic, homoallylic, and bis-homoallylic alcohols has b

188 onates add to glycolaldehyde imine to afford allylic hydroxyl allenes, and allyl boronates add to alk

189 surface pocket and interactions between the allylic hydroxyl group and the BTN3A1 backbone.

190 Protection of the allylic hydroxyl group of 3, followed by fluorination an

191 Readily accessed allylic hydroxylamine esters undergo copper hydride-cata

192 Their stability was attributed to the quasi-allylic interaction of their unpaired electrons with the

193 n of the main scenarios in the generation of allylic intermediates, radical species as formal nucleop

194 nce of a chiral copper catalyst, substituted allylic iodides couple with alpha-diazoesters to generat

195 The electron-withdrawing nature of the allylic leaving group facilitates the addition by negati

196 ienic systems and of the stereocenter at C2 (allylic methine, alpha to the carboxy group) and the pro

197 ctive conjugate addition of boron-stabilized allylic nucleophiles to alpha,beta-unsaturated ketones i

198 geometry of the enolate or the accompanying allylic olefin.

199 For cis allylic olefins, the trend is reversed.

200 For trans allylic olefins, the Z- and E-enol ethers proceed throug

201 lize diverse substrates containing benzylic, allylic or alpha-amino C-H bonds with high turnover and

202 inyldiazonium ions), vinyl carbocations, and allylic or homoallylic carbocation species via vinyldiaz

203 nyl benzyldimethylsilanes featuring adjacent allylic or homoallylic oxygen substituents by semihydrog

204 Subsequent allylic oxidation and diastereoselective hydride reducti

205 that shows a preference for epoxidation over allylic oxidation in the oxidation of cyclohexene.

206 ition toward the conjugated 1,3-diene or the allylic oxidation is faster.

207 The chemoselective allylic oxidation of ester-functionalized 1,4-dienes occ

208 Allylic oxidation of heteroatom substituted cyclic alken

209 oselective, regioselective and E/Z-selective allylic oxidation of unactivated internal alkenes via a

210 or the development of improved catalysts for allylic oxidation reactions.

211 However, a general and selective allylic oxidation using the more common internal alkenes

212 derwent Pd-catalyzed C-H bond activation and allylic oxidation.

213 ane family, followed by three site-selective allylic oxidations at C5, C10, and C13, which led to the

214 The successful strategy relied on late-stage allylic oxidations at two separate positions of the mole

215 ed allylic ammonium salt generation from the allylic phosphate and the glycine aryl ester.

216 ve cyclizations of substrates containing a Z-allylic phosphate tethered to an alkyne are described.

217 apid side reaction of a Cu-H complex with an allylic phosphate, while promoting its addition to an al

218 the resulting alkenylnickel species onto the allylic phosphate.

219 bining an allenylboronate, a hydride, and an allylic phosphate.

220 developed reaction conditions where racemic allylic phosphates are suitable substrates using new pho

221 ) (pin=pinacolato) and (E)-1,2-disubstituted allylic phosphates is introduced.

222 l-, alkenyl-, alkynyl- and alkyl-substituted allylic phosphates may thus be converted to the correspo

223 spectroscopy experiments on reactions using allylic phosphates showed the importance of allyl chlori

224 le N,N-disubstituted glycine aryl esters and allylic phosphates.

225 selective rhodium-catalyzed hydroboration of allylic phosphonates by pinacolborane affords chiral ter

226 More specifically, Z-chloro-substituted allylic pinacolatoboronate is first obtained through ste

227 wide range of nitrogen functionality at the allylic position of alkenes with unique regioselectivity

228 ential replacement of three C-H bonds at the allylic position of propylene and other simple terminal

229 lective installation of benzyl groups at the allylic position to forge tertiary and quaternary carbon

230 Deuteration of the allylic positions in cholesterol suppresses autoxidation

231 enium-catalyzed allylation of aldehydes with allylic pro-nucleophiles has been demonstrated to be an

232 The use of unsymmetrical allylic pro-nucleophiles was shown to give preferential

233 e access to enantiomerically enriched cyclic allylic products.

234 TfOH give rise to reactive conjugated CF(3)-allylic-propargylic cations [Ar-C=C-C(+)(CF(3))-CH=CH-Ar

235 Enantioselective nitrene insertion to allylic/propargylic C-H bonds was also achieved with rem

236 ol showed a lack of scrambling of a putative allylic radical at C-3 and C-4.

237 nsition metals as well as the utilization of allylic radical intermediates in beta-functionalization

238 ither delta (Z or E depending on whether the allylic radical is cis or trans) or beta to the OH group

239 Due to the enhanced stability of the allylic radical, however, these peroxy radicals lose O2

240 rapid intramolecular H(*) transfer, yielding allylic radicals (LZZ + S(*) right arrow over left arrow

241 Oxygen (O2) adds to these allylic radicals either delta (Z or E depending on wheth

242 .03 (1sigma) to produce two sets of distinct allylic radicals.

243 erve as glycoside mimics that are capable of allylic rather than oxocarbenium cation stabilization.

244 rd reagent, and associated position-specific allylic rearrangement in diastereoselective Pictet-Speng

245 e provided highly substituted trienes via an allylic ring opening followed by decarboxylation.

246 ueezing out the ligand from the conventional allylic S1 binding site, with proton abstraction being a

247 es and the reaction is also feasible with an allylic selenide.

248 ergo reverse hydroboration reactions to form allylic silanes or can be oxidized to afford highly subs

249 The chiral allylic silanes prepared here undergo a variety of stere

250 able functionalized allylic systems, such as allylic silanes, boronates, germanes, stannanes, pivalat

251 as been developed to prepare enantioenriched allylic silanes.

252 including disilylation, hydrosilylation, and allylic silylation under simple and transition-metal-fre

253 unsaturated fatty acids (PUFAs) at their bis-allylic sites has been identified as a unique approach i

254 eration that reinforces oxidation-prone, bis-allylic sites of PUFAs is a novel, nonantioxidant treatm

255 a silyl cyanide, an alkynyl stannane, and an allylic stannane were applicable to the present reaction

256 1,4-stereocontrol between the two respective allylic stereocenters.

257 cemic allylboronate reagent that contains an allylic stereogenic center, additions were exceptionally

258 d reduction of the hydrazone with an in situ allylic strain controlled retro-ene reaction of an allyl

259 a way to produce selectively functionalized allylic structures.

260 h correlated with the aggregrate size of the allylic substituent.

261 l pincer carbodicarbene ligand that delivers allylic substituted arenes in up to 95% yield and up to

262 f the 'click-to-release' reaction between an allylic substituted trans-cyclooctene linker and a tetra

263 ned Meyer-Schuster rearrangement/Tsuji-Trost allylic substitution clearly illustrates the enormous ad

264 udies of iridium-catalyzed, enantioselective allylic substitution enabled by (phosphoramidite,olefin)

265 e example of a regio- and diastereoselective allylic substitution in the absence of an exogenous liga

266 (2) a catalytic S(N)2'- and enantioselective allylic substitution method involving a mild alkylzinc h

267 io- and diastereoselective rhodium-catalyzed allylic substitution of challenging alkyl-substituted se

268 enophile, and subsequent palladium-catalyzed allylic substitution of the resulting cycloadduct with a

269 uction in an enantioselective intramolecular allylic substitution reaction catalyzed by a combination

270 oned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light.

271 g reaction shows that it involves an initial allylic substitution to form a new Michael acceptor, fol

272 The iridium-catalyzed asymmetric allylic substitution under biphasic conditions is report

273 +2]-photocycloaddition that undergoes formal allylic substitution with amine nucleophiles under Pd-ca

274 Enantioselective allylic substitution with enolates derived from aliphati

275 athway to obtain the latter (aka Tsuji-Trost allylic substitution), metal-catalyzed hydrofunctionaliz

276 treated with oxygen nucleophiles via formal allylic substitution, providing direct access to syn-1,4

277 ) )(2) Lewis acid catalyst system to promote allylic substitution, providing the C2-allylated product

278 in of stereoselectivity of copper enolate in allylic substitution.

279 kinetically competent to be intermediates in allylic substitutions of branched, racemic allylic alcoh

280 We report stereodivergent allylic substitutions with aryl acetic acid esters catal

281 enantioselective transformations, including allylic substitutions, conjugate additions, proto-boryl

282 ropic rearrangement of allylic sulfoxides to allylic sulfenates is a reversible process, generally sh

283 Fusing 1,6-diene with allylic sulfide or allylic sulfone motifs enabled a ring

284 ery facilitates an ene-cycloisomerization of allylic-sulfide-containing alkenylidenecyclopropanes (AC

285 r selectivity is obtained with both E- and Z-allylic sulfides and the reaction is also feasible with

286 Fusing 1,6-diene with allylic sulfide or allylic sulfone motifs enabled a ring-closing/ring-openi

287 The ability of 1,6-diene-fused allylic sulfone to undergo efficient SO(2) extrusion gen

288 The [2,3]-sigmatropic rearrangement of allylic sulfoxides to allylic sulfenates is a reversible

289 nert unactivated acyclic internal olefins as allylic surrogates.

290 lysis leads to rearomatizing gamma-selective allylic Suzuki-Miyaura cross-coupling to generate 1,1-di

291 enables synthesis of valuable functionalized allylic systems, such as allylic silanes, boronates, ger

292 ylpalladium(II) electrophiles generated from allylic tert-butyl carbonates.

293 alkenes with unique regioselectivity and no allylic transposition.

294 The rearrangement of allylic trichloroacetimidates is a well-known transforma

295 p and ligand to enable conversion of racemic allylic trichloroacetimidates to the corresponding enant

296 d nucleophilic fluoride source (Et(3)N.3HF), allylic trichloroacetimidates undergo rapid fluoride sub

297 ent (CF(3)SO(2)Na) is reported to synthesize allylic trifluoromethylated derivatives.

298 The first palladium-catalyzed asymmetric allylic trifluoromethylation is disclosed.

299 Allylic trifluoromethylation was achieved by a photo-oxi

300 different fragmentation pathways enabled by allylic versus vinylic carbons.

301 Despite the importance of allylic ylide rearrangements for the synthesis of comple