ライフサイエンスコーパス: alpha

1 elative to the long-term population median F/alpha.

2 of caspase-8, TNFR1, and increased serum TNF-alpha.

3 ILP with melphalan and tumor necrosis factor-alpha.

4 and SOL data was analyzed using GLM and SNK (alpha = 0.05) and CYTO data was analyzed with Kruskal-Wa

5 analyzed with Kruskal-Wallis and SNK tests (alpha = 0.05).

6 tuin, asialofetuin, IgG, ribonuclease B, and alpha-1 acid glycoprotein (AGP) by PGC-LC-MS.

7 ke exposure using deep gene resequencing and alpha-1 antitrypsin concentrations.Methods: DNA samples

8 ing neutrophil elastase for the treatment of alpha-1 antitrypsin deficiency.

9 rare variant genotypes in the gene encoding alpha-1 antitrypsin, SERPINA1 (serpin peptidase inhibito

10 (myeloperoxidase, neopterin), permeability (alpha-1-antitrypsin, lactulose, mannitol), and repair (r

11 A linear alpha-(1,4)-glucosamine tetrasaccharide was assembled to

12 l-subset Hessians of all the TSs but not the alpha-(14)CIPFRs.

13 c-electron microscopy structure of an active alpha(2)beta(2) complex are performed to examine the str

14 We first demonstrated that alpha(2)M* induced trophoblastic cell fusion.

15 viruses containing both a stabilized HA and alpha-2,6 receptor binding in tandem pose greater pandem

16 re, we investigated the role of leucine-rich alpha-2-glycoprotein 1 (LRG1) in normal and diabetic wou

17 is mediated by MAdCAM, the natural ligand of alpha(4)beta(7) that is expressed on gut endothelial cel

18 Trafficking of alpha(4)beta(7)-expressing lymphocytes to the gut is med

19 xpression of human signal regulatory protein alpha, a negative regulator of macrophage phagocytosis a

20 acid (P6C), alpha-aminoadipic semialdehyde (alpha-AASA) and pipecolic acid both in brain and liver t

21 folding of a titin immunoglobulin domain and alpha-actinin spectrin repeats.

22 ge of cortical mechanical tension, rendering alpha-actinin-4 a catch bond in physiological tension ra

23 apply our approach to the actin cross-linker alpha-actinin-4 and show that the cross-linking time of

24 in-4 and show that the cross-linking time of alpha-actinin-4 homodimers increases approximately twofo

25 alpha-Actinins are major F-actin bundlers that are inhib

26 ion of TIPS-protected enoldiazoacetates with alpha-acyl sulfur ylides, has been developed.

27 ursors, including those that generate alkyl, alpha-acyl, trifluoromethyl and sulfonyl radicals.

28 T-MD) simulations of SCN(-) near the neutral alpha-Al(2)O(3)(0001)/H(2)O interface show that the vSFG

29 groups were converted into the corresponding alpha-alkylated products in good yields.

30 atalytic procedure for the direct asymmetric alpha-allylation of branched aldehydes.

31 alpha,alpha'-Dibenzoylbenzodipyrroles were characterized

32 r Curtin-Hammett control via a more reactive alpha,alpha-bisboryl tertiary allylcopper species to fur

33 o-2-thioxothiazolidin-5-ylidene)acetates and alpha,alpha-dicyanoolefines under ultrasound (US) irradi

34 ionalization to a variety of enantioenriched alpha,alpha-difluoromethylene-containing products.

35 he direct or one-pot sequential synthesis of alpha,alpha-disubstituted ketones via the alkylation of

36 y using NS9283 stimulation at the unorthodox alpha-alpha nicotinic binding site.

37 direct nucleophilic attack by the substrate alpha-amino group on the sn-2 ester to form a cyclic tet

38 e the activity of oligodendrocyte NMDARs and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid

39 adation, an unstable metabolic intermediate, alpha-amino-beta-carboxymuconate-epsilon-semialdehyde (A

40 Delta1-piperideine-6-carboxylic acid (P6C), alpha-aminoadipic semialdehyde (alpha-AASA) and pipecoli

41 in the order of seconds) with Human Salivary alpha-amylase (HSA) and Porcine Pancreatic alpha-amylase

42 y alpha-amylase (HSA) and Porcine Pancreatic alpha-amylase (PPA).

43 Lines carrying AG1 + AG2 QTLs showed higher alpha-amylase activity, leading to rapid starch degradat

44 d higher inhibitory activity with respect to alpha-amylase and tyrosinase.

45 with anti-diabetic properties because strong alpha-amylase inhibition generally causes undesired side

46 Enzymes including papain, alpha-amylase, glucose oxidase and phytase stabilized do

47 p to 90% cleavage from 5-nt bulge-loops (BC5-alpha and BC5L-beta anomers) through multiple cuts, incl

48 evidence of vertical stratification in both alpha and beta (compositional) diversity of airborne bac

49 Comparing alpha and beta gene occupancy at PPP sites and gene bodi

50 generates effector gradients where importins alpha and beta gradually tune the activities of spindle

51 TBT, oysters substantially up-regulated HIF1-alpha and down-regulated Tbeta-4, although hemocyte coun

52 ing with neutralizing antibodies against TNF-alpha and IFN-gamma protected mice from mortality during

53 n of pro-inflammatory mediators, such as TNF-alpha and IL-6.

54 is due to acute and reversible action of TNF-alpha and is not associated with increased human-Abeta l

55 D kidneys, except that tumor necrosis factor alpha and monocyte chemotactic protein 1 expression was

56 rator-activated receptor gamma coactivator 1-alpha and oxidative phosphorylation complex II and III w

57 topoisomerase II (topo II) isoforms, topo II alpha and topo IIbeta.

58 e levels of tumor necrosis factor-alpha (TNF-alpha) and cytokine-induced neutrophil chemoattractant-1

59 Here, by combining femtosecond Fe K(alpha) and K(beta) X-ray emission spectroscopy (XES) wit

60 element- and spin-sensitive femtosecond Fe K(alpha) and K(beta) X-ray emission spectroscopy at an X-r

61 ty, elevated expression of estrogen receptor alpha, and increased DNA damage in cells.

62 been marked by elevation of IL-6, IL-10, TNF-alpha, and other cytokines and severe CD4(+) and CD8(+)

63 ate-lowering medication were associated with alpha- and beta-diversity.

64 evealed the arrangement of multiple forms of alpha- and beta-polypeptides in an individual LH1 ring.

65 haemoglobin, a heterotetramer of paralogous alpha- and beta-subunits that mediates respiratory oxyge

66 the gene duplication that generated distinct alpha- and beta-subunits.

67 rved for the P2 and P3 peptides derived from alpha- and gamma-gliadins.

68 methotrexate, cyclosporine, tacrolimus, TNF-alpha antagonists, vedolizumab, tofacitnib, or ustekinum

69 ain-containing 3 (Arrdc3) is a member of the alpha-arrestin family previously linked to human obesity

70 alpha-Arylation of alpha,beta-unsaturated ketones consti

71 The direct alpha-arylation of carbonyl compounds emerged over the l

72 ints to NAAA-regulated PEA signaling at PPAR-alpha as a critical control point for the induction and

73 ch idiosyncratic biases could be spontaneous alpha band activity, a prominent brain rhythm known to i

74 he photochemical transformation of 4-hydroxy-alpha-benzopyrones to a new series of biorelevant 2-hydr

75 the formation of a ketoimine rather than an alpha,beta-dehydro-amino acid intermediate during C(alph

76 a metal-free domino synthesis of Z-selective alpha,beta-diphenylthio enones is developed from easily

77 n and are members of the RsbQ-like family of alpha,beta-hydrolases.

78 Based on the binding mode of adenosine 5'-(alpha,beta-methylene)diphosphate (AOPCP) with human CD73

79 hylenecyclopropanes and a broad selection of alpha,beta-unsaturated aldehydes.

80 A series of steroidal alpha,beta-unsaturated hydrazones is presented whose beh

81 alpha-Arylation of alpha,beta-unsaturated ketones constitutes a powerful sy

82 ditional examples of cascade cyclizations of alpha,beta-unsaturated thioesters proceeding are reporte

83 , consisting of water-soluble azobenzene and alpha-, beta-, or gamma-cyclodextrins, have been propose

84 There was poor inter-rater reliability of Alpha/Beta classification (mean kappa = 0.31).

85 AD2(F135A), having substitutions in the core alpha/beta hydrolase-fold domain and the hairpin, exhibi

86 Sheet/barrel and mixed-alpha/beta proteins exhibit more conventional structure-

87 o MDM2, and to a family of 3-19 nM-affinity, alpha/beta-peptide-based binders to 14-3-3.

88 thetic route, including (i) CuBr(2)-mediated alpha-bromination of o-arylacetophenone, (ii) sequential

89 l nucleophilic substitution of the resulting alpha-bromo o-arylacetophenone with sodium sulfinate (RS

90 This effect is blocked by both alpha-bungarotoxin and apamin, indicating coupling of AC

91 d antibody that neutralized interferon (IFN)-alpha, but not IFN-gamma.

92 ition to the alkene, to the more substituted alpha-carbon is 3.6 kcal/mol lower than that to the beta

93 We report a Ni-catalyzed regioselective alpha-carbonylalkylarylation of vinylarenes with alpha-h

94 the envelope membrane that interact with the alpha-carboxyltransferase (alpha-CT) subunit of ACCase a

95 cyte model system, we show that depletion of alpha-catenin perturbs adherens junctions, enhances cell

96 simple peptides that bind alpha-cobratoxin (alpha-Cbtx) and prevent its inhibition of nicotinic acet

97 especially tumor necrosis factor alpha (TNF-alpha), CCL3, CCL4, and CCL20, their HIV-1 reactivation

98 Urinary and plasma d3- and d6-alpha-CEHC concentrations varied differently with the in

99 se but also results in hyperglucagonemia and alpha-cell hyperplasia.

100 The resulting SC-alpha cells do not express insulin, share an ultrastruct

101 share an ultrastructure similar to cadaveric alpha cells, express and secrete glucagon in response to

102 riments, PC2 immunoreactivity in neighboring alpha-cells acted as a positive control.

103 alpha-cells did not express Glp1r mRNA and delta-cells e

104 h beta-fluoride elimination of the generated alpha-CF(3) carbanions.

105 res, we found that the concentrations of TNF-alpha change little from day 3 to day 5-6, but the conce

106 olecules, stereospecific synthesis of useful alpha-chiral alkyl amines, and rapid construction of dif

107 The chemical proteomic discovery of alpha-chloroacetamide (alphaCA) compounds that covalentl

108 zation, we present simple peptides that bind alpha-cobratoxin (alpha-Cbtx) and prevent its inhibition

109 This error signal is accompanied by alpha coherence between the two regions.

110 Finally, micro-infusion of alpha-conotoxin AuIB (10 mum) but not alpha-conotoxin MI

111 the alpha3beta4* nAChR-selective antagonist alpha-conotoxin AuIB almost completely abolished nicotin

112 ion of alpha-conotoxin AuIB (10 mum) but not alpha-conotoxin MII (10 mum) into the IPn in rats increa

113 Point mutations in cysteine string protein-alpha (CSPalpha) cause dominantly inherited adult-onset

114 n carboxylase (BC), carboxyltransferase (CT)-alpha, CT-beta, and biotin carboxyl carrier protein (BCC

115 interact with the alpha-carboxyltransferase (alpha-CT) subunit of ACCase and participate in an origin

116 atory markers (IL-6, IL-1beta, COX-2 and TNF-alpha) decreased.

117 Synthetic human alpha-defensin 5 (HD5) was orally given to alcohol-fed m

118 gnals for dioxgen availability-dependent HIF-alpha degradation via the ubiquitin proteasome system.

119 I(Kur)) and F(2)-isoprostanes, NOX2, and PKC-alpha/delta expression and atrial fibrosis were signific

120 arate, we compared (13)CO-detect versus (1)H(alpha)-detect experiments, showing that significant sens

121 adation reactions were found responsible for alpha-dicarbonyl compound formation.

122 y) in the cue-to-target foreperiod, only EEG alpha differed with the to-be-attended object category.

123 rochlorococcus, and high microbial community alpha diversity.

124 ing have made any estimate of within-sample (alpha) diversity uncertain.

125 and 6-month mean, 0.85 [95% CI, .1-1.7]) and alpha-diversity (P = .0045).

126 fferences in taxonomic or functional pathway alpha-diversity between CTX-T and CTX-N infants.

127 ng for HIV status, women displayed increased alpha-diversity compared with MSW.

128 of disease presence (or absence) compared to alpha-diversity indices.

129 Among the 1249 samples analyzed, the alpha-diversity of the fecal microbiome was unchanged am

130 95, and 52.28% for linoleic, oleic, punicic, alpha-eleostearic, catalpic, and beta-eleostearic acids

131 with tracers for imaging and with beta- and alpha-emitter radionuclides for radioimmunotherapy.

132 Estrogen receptor alpha (ERalpha) is a ligand-dependent transcription regu

133 n in the gene encoding the estrogen receptor alpha (ERalpha) was previously identified in a female pa

134 expression (SATB1) and the estrogen receptor alpha (ESR1).

135 Importantly, restoration of hepatic G6Pase-alpha expression in G6pc-/- mice corrects defective auto

136 With alpha-FAD(*-), the reduction of beta-FAD with NADH was 1

137 after accounting for etiology of cirrhosis, alpha-fetoprotein (AFP) at liver transplant, tumor diame

138 igh level expression of active beta-catenin, alpha-fetoprotein, and SOX9, suggesting that DCLK1 overe

139 to a clinical diagnosis and was superior to alpha-fetoprotein.

140 aloe-emodin with both the ethynyl and the N(alpha)Fmoc-l-Lys groups showed an antioxidant activity-e

141 reaction of beta-ketosulfones with different alpha-functionalized nitroalkenes affords diversely subs

142 tivate basophils sensitized with plasma from alpha-gal allergic subjects in an IgE-dependent manner s

143 sing alpha-Gal epitopes because they express alpha-Gal epitopes and lack anti-Gal Abs.

144 to test the efficacy of vaccines expressing alpha-Gal epitopes because they express alpha-Gal epitop

145 ere we investigated the epidemiology of the "alpha-Gal syndrome" in the United States and sought addi

146 To our knowledge, our new Hu-NSG/alpha-Gal(null) is the first available humanized mouse m

147 Alpha-gal-containing glycolipids activate basophils sens

148 desired products in up to 91 % yield, >98:2 alpha:gamma selectivity, >98:2 Z:E selectivity, and >99:

149 alpha genes at 3 hpi and that repression of alpha gene expression late in infection is mediated by p

150 ndividuals and positively corelated with TNF-alpha gene expression.

151 At that time, Pol II on alpha genes accumulated most heavily at promoter-proxima

152 ficiently into the bodies of beta genes than alpha genes at 3 hpi and that repression of alpha gene e

153 s while Pol II pausing remained prominent on alpha genes.

154 t metabolize either glycogen or starch (both alpha-glucans) or other polysaccharides tested.

155 roteins were identified: legumin (Pru du 6), alpha-hairpinin (Pru du 8), and mandelonitrile lyase (Pr

156 In contrast, by exploration of alpha-halo ketone in amine as a halide precursor, differ

157 a-carbonylalkylarylation of vinylarenes with alpha-halocarbonyl compounds and arylzinc reagents.

158 The alpha has high interspecific repeat homogeneity and was

159 ease of delta(13)C and delta(37)Cl values of alpha-HCH indicated its transformation in soil and wheat

160 drophobicity and particle size increased and alpha helical structure decreased, reducing the stabilit

161 Interleukin-2 (IL-2) is a small alpha-helical cytokine that regulates immune cell homeos

162 Alpha-helical integral membrane proteins contain conserv

163 70 binding and unbinding events between the alpha-helical molecular recognition element (alpha-MoRE)

164 s as a stabilizer of MEILB2 by binding to an alpha-helical N-terminus of MEILB2 and preventing MEILB2

165 ol and an endogenous substrate resembling an alpha-helical TM.

166 The oncogenic spacer region is alpha-helical, which contrasts with previous suggestions

167 op spanning K61 to I72 and flanked by longer alpha-helices at the outer edges, and basic side grooves

168 t two Rab33B molecules bind to the diverging alpha-helices of the dimeric Atg16L1 coiled-coil domain.

169 om a conformationally disordered state to an alpha-helix and develops contacts with the C-terminal do

170 patch regions through the SMARCB1 C-terminal alpha-helix and the SMARCA4/2 C-terminal SnAc/post-SnAc

171 active site, including the translation of an alpha-helix by 1 angstrom.

172 er to be collagen losing its original triple alpha-helix conformation, further confirming the diagene

173 a surface groove to capture the critical BH3 alpha-helix of pro-apoptotic members.

174 protein complexes reveal a disruption in the alpha-helix of transmembrane segment 6 (TM6) not observe

175 yloid-beta(1-40) was less prone to adopt the alpha-helix secondary structure.

176 t algorithm made further improvements to the alpha-helix SSEs of the backbone trace.

177 lpha-helix-to-beta-strand and beta-strand-to-alpha-helix transitions and domain motions displayed by

178 re, we conducted an in-depth analysis of the alpha-helix-to-beta-strand and beta-strand-to-alpha-heli

179 nscription factor hypoxia-inducible factor 2 alpha (Hif2alpha), which is induced in subluminal stroma

180 reduction of a product to the corresponding alpha-hydroxylsilane in one pot.

181 iciency results in reduced production of TNF-alpha, IL-6, and IL-1beta and in limited M1 macrophage p

182 ytokines and chemokines, including IL-1, TNF-alpha, IL-9, CXCL1, CCL2, and CCL5 in the bronchoalveola

183 The functions of importin-alpha/importin-beta and importin-11 have been verified i

184 findings support a profibrotic role of PDGFR-alpha in HSCs during chronic liver injury in vivo via re

185 l GTPases, tumour necrosis factor-alpha (TNF-alpha)-induced signalling and prevention of cell death.

186 Switch I and effector-binding regions, (ii) alpha-interface at the allosteric lobe.

187 These results underscore the role of the alpha-interface in K-Ras4B homodimerization and the beta

188 n 4-vinylguaiacol, acetovanillone, and 3-oxo-alpha-ionol, providing spicy and fruity notes at the sen

189 nal-group tolerance with respect to both the alpha-ketoacetal and amine coupling partners, providing

190 o serine synthesis, which in turn stimulates alpha-ketoglutarate-dependent dioxygenases that remove t

191 uct, dibenzosuberenone, bearing a beta-amino-alpha-ketone group was secured by X-ray crystallography.

192 However, the central role of alpha-klotho in metabolism remains largely unexplored.

193 ts indicate a prominent role of hypothalamic alpha-klotho/FGFR1/PI3K signaling in the modulation of N

194 HlyA preferentially binds the alpha(L)beta(2) integrin LFA-1 (CD11a/CD18) of leukocyte

195 ended to the detection and identification of alpha-l-arabinofuranosidases produced by eight biomass-d

196 ncover a frame-shift insertion affecting the alpha-L-iduronidase (IDUA) gene (c.19_20insCGGCCCCC), a

197 ee activities needed to synthetize the 2-OMe-alpha-l-Rha-(1->2)-beta-l-Rha fragment.

198 ctoglobulin (beta-Lg) and alpha-lactalbumin (alpha-La), was achieved after 4 h, at E/S ratios of 1/15

199 y proteins, beta-Lactoglobulin (beta-Lg) and alpha-lactalbumin (alpha-La), was achieved after 4 h, at

200 he lower energy barrier for the formation of alpha-lapachone is a result of lower Pauli repulsion thr

201 000 copies/mL was associated with higher TNF-alpha levels (P = .013).

202 alpha-Linked galactose is a common carbohydrate motif in

203 hilic fraction, containing 43.3 and 37.4% of alpha-linolenic and linoleic fatty acids, respectively.

204 ved after other types of liver injury, PDGFR-alpha loss in HSCs led to a significant albeit transient

205 55 is a putative cannabinoid receptor, and l-alpha-lysophosphatidylinositol (LPI) is its only known e

206 iments showed that vinculin, talin, integrin alpha(M)beta(2), and other components of podosomes are p

207 4 ns and a minimum absorption coefficient of alpha(min) = 1.67 x 10(-6) cm(-1).

208 ion strategy to expand the interlayer gap of alpha-MoO(3), in which water molecules take the place of

209 olecules take the place of lattice oxygen of alpha-MoO(3).

210 alpha-helical molecular recognition element (alpha-MoRE) of the intrinsically disordered C-terminal d

211 This pentaloop is recognized by the sterile alpha motif domain-containing ZCCHC14 protein, which in

212 ly blocks progression of disease and further alpha-motoneuron degeneration.

213 The G(s)alpha mutation results in dysregulation of the cAMP sign

214 rosothiols to solutions of NBT plus beta- or alpha-NADP did not produce diformazan, (5) S-nitrosothio

215 rosothiols to solutions of NBT plus beta- or alpha-NADPH elicited rapid formation of diformazan in th

216 (2) addition of S-nitrosothiols or beta- or alpha-NADPH to solutions of NBT did not elicit diformaza

217 apacity was almost completely blocked by TNF-alpha neutralization alone.

218 with a total of 13 items, overall Cronbach's alpha of 0.93, and test-retest reliability of 0.66.

219 iated with anticipatory states of attenuated alpha oscillations and the CNV.

220 Both CFS and PAC networks coupled theta and alpha oscillations with higher frequencies in large-scal

221 We used alpha particles from an (241)Am source as a proxy for th

222 e bands of austenite (gamma) and martensite (alpha' ) phases on the partitioning of stress and strain

223 ed with appreciated sensory properties, with alpha-pinene as the main volatile (14.47-37.09 mg/kg).

224 e bond as the only functional group, such as alpha-pinene, beta-pinene and camphene, or two alkene mo

225 telet-derived growth factor receptor (PDGFR)-alpha plays roles in cell survival, proliferation, and d

226 mma chain-/- human signal regulatory protein alpha-positive (RRGS) rats combining Rag1 and Il2rg defi

227 The extent of alpha power modulations within participants was negative

228 Support vector machine decoding of alpha power patterns revealed that late (>500 ms latency

229 ent task, we here tested the hypothesis that alpha power reflects the overcoming of an idiosyncratic

230 Change in theta, but not alpha power, between meditation and rest was positively

231 Peroxisome proliferator-activated receptor alpha (PPARalpha) is expressed in retinal Muller cells,

232 y peroxisome proliferator-activated receptor alpha (PPARalpha), suggesting that FATP2 activity is lin

233 ) and 91.0% (females) of variance in adult F/alpha ratios relative to the long-term population median

234 use the in-medium contribution to the triple-alpha reaction rate must be present at high densities, t

235 the virus rapidly evolves to exploit the IFN-alpha response for its replication, spread, and pathogen

236 crocyclic peptide overlays well with that of alpha-RgIA4, demonstrating that the cyclization does not

237 of episodic memory and highlight the role of alpha rhythms in revealing when and where different type

238 ffectively reduces neutrophil migration, TNF-alpha secretion, and tissue inflammation in mice (female

239 The experimentally observed alpha-selectivity was explored in detail, revealing that

240 e autophagy, restores SIRT1/FoxO3a/AMPK/PPAR-alpha signaling and rectifies metabolic abnormalities.

241 Estrogen receptor -alpha signaling increased IL-33 release and ILC2-mediate

242 greater levels of alpha-smooth muscle actin (alpha-SMA) expression, and exerted larger traction force

243 t stress fibers, exhibited greater levels of alpha-smooth muscle actin (alpha-SMA) expression, and ex

244 targets CD144, Neuroligin 1 (NLGN1), and TNF-alpha-stimulated gene/protein 6 (TSG-6).

245 ession following TNF (tumor necrosis factor)-alpha stimulation.

246 a-structures and then to kinetically trapped alpha-structures.

247 Injection of inhibitory antibodies to the alpha subunit of the Gs heterodimeric protein (GalphaS)

248 The inhibitory G protein alpha-subunit (Galpha(z)) is an important modulator of b

249 ng increased expression of the IL-2 receptor alpha-subunit and activation of the transcriptional regu

250 Vertebrate genomes contain three alpha subunits encoded by three different genes and CAPZ

251 ological gating cooperativity between Nav1.5 alpha-subunits.

252 It was noted that these 1:1 alpha/Sulfono-gamma-AA peptides were completely resistan

253 ith anxiety-like behavior in aged PD-related alpha-syn A53T mice.

254 kout could modestly promote the formation of alpha-syn aggregates, accelerate the severe and progress

255 sensory-evoked fMRI on 20 mice injected with alpha-syn fibrils and 20 PBS-injected mice at three time

256 based on the atomic structure of the core of alpha-syn fibrils.

257 t increase the amount of insoluble monomeric alpha-syn or its phosphorylation status.

258 crostructure, functional brain activity, and alpha-syn pathology by longitudinally conducting rotarod

259 YO7B) as critical endocytosis regulators for alpha-Syn preformed fibrils (PFFs).

260 erexpression of C/EBPbeta in human wild-type alpha-Syn transgenic mice facilitates PD pathologies and

261 inclusions with aggregated alpha-synuclein (alpha-Syn) as the major component.

262 aggregation of the protein alpha-synuclein (alpha-Syn) leads to different synucleinopathies.

263 ciated with augmentation of delta-secretase, alpha-Syn, and MAOB.

264 novel and preferential option to ameliorate alpha-syn-induced neurodegeneration.

265 al Lewy body (LB) inclusions with aggregated alpha-synuclein (alpha-Syn) as the major component.

266 The aggregation of the protein alpha-synuclein (alpha-Syn) leads to different synuclein

267 A key therapeutic target in PD is alpha-synuclein (alphaS), which is both genetically impl

268 ever, it remains uncertain where the initial alpha-synuclein aggregates originate.

269 lex displays a contact between alanine 53 of alpha-synuclein and glutamine 111 in the catalytic pocke

270 etric assay of two internal exosome markers (alpha-synuclein and syntenin-1) from neuronal exosomes.

271 thiolate-linked diubiquitin and an ubiquitin-alpha-synuclein conjugate.

272 ent area for the propagation of pathological alpha-synuclein from the periphery to the brain.

273 Parkinson's disease (PD)-associated protein alpha-synuclein in cells and interacts with alpha-synucl

274 alpha-synuclein in cells and interacts with alpha-synuclein oligomers.

275 ic studies revealed that Synucleozid reduces alpha-synuclein protein levels by decreasing the amount

276 tudinal sample analysis showed that exosomal alpha-synuclein remains stably elevated with Parkinson's

277 on membrane-catalyzed amyloid aggregation of alpha-synuclein, a protein implicated in Parkinson's dis

278 pace of the intrinsically disordered protein alpha-synuclein.

279 on two major pathological proteins: tau and alpha-synuclein.

280 Among the 444 incident cases of alpha-synucleinopathy, 86 were clinically diagnosed with

281 Second trimester maternal plasma alpha-T concentration was 3-fold higher than in the adul

282 m-extracted Hessian reproduces perfectly the alpha-T(3) IPFR values from the full-subset Hessians of

283 eta-dehydro-amino acid intermediate during C(alpha)-thioether bridge LC-MS/MS fragmentation.

284 measure the levels of tumor necrosis factor-alpha (TNF-alpha) and cytokine-induced neutrophil chemoa

285 chemokines, especially tumor necrosis factor alpha (TNF-alpha), CCL3, CCL4, and CCL20, their HIV-1 re

286 Rab27 small GTPases, tumour necrosis factor-alpha (TNF-alpha)-induced signalling and prevention of c

287 Modulations of oscillations in the alpha to beta range in task-relevant sensory regions hav

288 ctive lipid LPA drives the expression of TNF-alpha to regulate an inflammatory network in ovarian can

289 ized the small molecule inhibitor, pifithrin-alpha, to inhibit p53 signaling, and nutlin-3a, a small

290 Viable seeds contained higher levels of alpha-tocopherol (6.7 mg/100 g), lipids (23.11 g/100 g,

291 ther ATG proteins mediate protection against alpha-toxin through the release of ADAM10 on exosomes-ex

292 for mitotic error correction is regulated by alpha-tubulin detyrosination remains unknown.

293 pitation and mass spectrometry analysis that alpha-tubulin interacts with galectin-8 during mitosis.

294 f 10-80% mixture of acetylated/nonacetylated alpha-tubulin peptides in the background of human olfact

295 which, in turn, inhibits the acetylation of alpha-tubulin, and promotes the dynamic assembly of micr

296 to the peptide content and abrogated by anti-alpha(v)beta(3)) but not by A2780 (same as PEGylated par

297 This case suggests that (18)F-alpha(v)beta(6)-BP PET/CT is a promising noninvasive app

298 he vestibule regions, conserved only in YfdC-alpha, were found to be responsible for high energy barr

299 therapeutic target in PD is alpha-synuclein (alphaS), which is both genetically implicated and accumu

300 Following rain, alpha (within-sample) diversity measured on cucumber and