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1  was associated with increased expression of alpha6 integrin.
2 ta-catenin, also inhibited the expression of alpha6 integrin.
3 immunoprecipitated together with laminin and alpha6 integrin.
4 ns are co-expressed at the cell surface with alpha6 integrin.
5 -deficient skin adhered to laminin-5 through alpha6 integrins.
6 ing a functional cross-talk between CD82 and alpha6 integrins.
7 esulted from less cell surface expression of alpha6 integrins.
8  beta1 integrins, but not alpha4, alpha5, or alpha6 integrins.
9 ranslated regions of proinvasive alphav- and alpha6-integrins.
10  selectively and specifically bound to human alpha6 integrin, a 120-kDa protein present in gingiva an
11 protein laminin through cooperation with the alpha6 integrin, a specific laminin receptor.
12            Cultured keratinocytes expressing alpha6 integrin, a transmembrane protein known to bind L
13                         In addition, without alpha6 integrin, activation and expression of NFkappaB w
14 ceptors, including integrin-alpha3, integrin-alpha6, integrin-alpha7, integrin-beta1, integrin-beta4,
15 and expression of the cell surface molecules alpha6-integrin, alphav-integrin, and the c-kit receptor
16 re suppressed by Lama5 through the receptors alpha6 integrin and alpha-dystroglycan.
17 ough smooth muscle and tumor coexpression of alpha6 integrin and E-cadherin in a cell-cell location a
18 ment membrane proteins and reduced levels of alpha6 integrin and FGF2.
19                 They find that expression of alpha6 integrin and its splice variants differs between
20  show that IGF-1R activation is dependent on alpha6 integrin and that this transactivation requires S
21 6beta4, help contain retraction and both the alpha6 integrins and alpha3beta1 integrin contribute to
22 es suggest that HPV infection is mediated by alpha6-integrin and/or heparan-sulfonated receptors.
23 unction-perturbing anti-beta1 integrin, anti-alpha6 integrin, and anti-laminin antibodies respectivel
24  autoantibody, antibodies to human beta4 and alpha6 integrins, and sera from patients with BP showed
25 scattering properties, positive staining for alpha6-integrin, and negative or low alphav-integrin exp
26 y anti-beta1 integrin antibodies and by anti-alpha6 integrin antibodies.
27 so inhibited by anti-beta1 integrin and anti-alpha6 integrin antibodies.
28  on morphogenesis in vivo was seen with anti-alpha6 integrin antibody, suggesting that alpha6 is not
29  mouse testis cells with anti-beta1- or anti-alpha6-integrin antibody, but not anti-c-kit antibody, p
30 sal type II hemidesmosomes disappear and the alpha6 integrins appear evenly distributed over lamellae
31 e yeast two-hybrid assay, we have identified alpha6 integrin as a BP180-binding partner.
32                                  We identify alpha6-integrin as a mechanosensing integrin subunit tha
33 which proliferating keratinocytes expressing alpha6 integrin at the site of epithelial wounding might
34 tion of function-blocking antibodies against alpha6 integrin, beta1 integrin or the laminin-1/E8 doma
35 ificantly reduced the expression of integrin alpha6, integrin beta4, Fak, paxillin, Rac1/2/3, and ROC
36  (p<0.05), identifying this population as an alpha6 integrin bright subset.
37 phenotype of the MHC-I-Thy-1+c-kit- SSCs was alpha6-integrin+CD24+alphavintegrin-Sca-1-CD34-.
38 ogenitors: podocalyxin-like protein (PODXL), alpha6-integrin (CD49f), alpha4-integrin (CD49d), c-Met,
39  of the CD82-integrin alpha6 complex reduces alpha6 integrin cell surface expression.
40  causes an aberrant VE-cadherin, laminin and alpha6 integrin distribution in vessels, along with sign
41                   In contrast, cells without alpha6 integrin (DU145 alpha6KO) and cells expressing an
42             Prostate cancer cells expressing alpha6 integrin (DU145 alpha6WT) produced a 3D invasive
43 xpression and changing pattern of alpha3 and alpha6 integrins during development of the mammalian inn
44 during gamete fusion; yet, eggs null for the alpha6 integrin exhibit normal fertilization.
45 model for examining the relationship between alpha6 integrin expression and cell differentiation, sin
46                          First, reduction of alpha6 integrin expression does not halt mitotic divisio
47 n epidermis from several body sites, whereas alpha6 integrin expression is more uniform.
48 urface phenotype (low beta1 integrin and low alpha6 integrin expression) than label-retaining keratin
49 extravillous differentiation, with decreased alpha6 integrin expression, increased alpha1, and elevat
50 disrupted or unaffected by a perturbation of alpha6 integrin expression.
51 ugh its direct interactions with alphav- and alpha6-integrin expression.
52 ults suggest that gene editing of a specific alpha6 integrin extracellular region, not required for n
53 he muscle through gene editing of a specific alpha6 integrin extracellular region.
54                                  Blocking of alpha6-integrin function by inhibitory antibody prevents
55 the first time, a homozygous mutation in the alpha6 integrin gene (ITGA6) in a family with three affe
56 n and E-cadherin in a cell-cell location and alpha6 integrin in a cell-extracellular matrix (ECM) dis
57 tively selected using antibodies to CD34 and alpha6 integrin in combination with fluorescent activate
58                                 Knockdown of alpha6 integrin in keratinocytes not only results in mot
59 cess; 2) the decreased surface expression of alpha6 integrins in CD82-expressing cells is likely resp
60 s lung myofibroblasts express high levels of alpha6-integrin in vitro and in vivo.
61                   Moreover, re-expression of alpha6 integrin increases beta4 integrin protein at the
62 e support for the possibility that BP180 and alpha6 integrin interaction is not only mediated by the
63                             We conclude that alpha6 integrin is an essential upstream regulator of th
64 ay different roles during brain development: alpha6 integrin is essential for migration of tectal cel
65                          We demonstrate that alpha6 integrin is likely to mediate the inductive effec
66 4 integrins are sensitive to Amino-Nogo, but alpha6 integrin is not.
67                  These findings suggest that alpha6-integrin is a matrix stiffness-regulated mechanos
68                         In studies with both alpha6 integrin knock-out mice lenses and primary lens c
69 ssion of either alpha6 or alpha3 integrin in alpha6 integrin knockdown cells restores alpha2 integrin
70 alpha2 integrin mRNA levels are decreased in alpha6 integrin knockdown cells, alpha3 and beta4 integr
71 ed on inhibition of fertilization by an anti-alpha6 integrin mAb (GoH3), suggest that the alpha6beta1
72 ation, indicating that redistribution of the alpha6 integrins may contribute to the protrusion of the
73  subsequently, results in the attenuation of alpha6 integrin-mediated cellular morphogenesis; and 3)
74 ken together, these data indicate that while alpha6 integrin-mediated interactions with laminin are r
75 on between specific domains of the BP180 and alpha6 integrin molecules is inhibited by a 14 mer pepti
76 n, CD34+ keratinocytes were found to express alpha6 integrin more intensely than CD34- cells (p<0.05)
77                        Notably, the level of alpha6 integrins on the cell surface was down-regulated
78 inin alpha5 receptors were blocked with anti-alpha6 integrin or anti-alpha-dystroglycan (alphaDG) mon
79                                         Anti-alpha6 integrin or anti-DG prolonged allograft survival.
80                                          The alpha6 integrins, particularly alpha6beta4, help contain
81 ession of several transcripts is expanded in alpha6 integrin-perturbed embryos (orthodenticle and eng
82 e late in neurulation, is abolished in these alpha6 integrin-perturbed embryos.
83 rmation, brachyury, is expressed normally in alpha6 integrin-perturbed embryos.
84  analysis identified a group of iPSC-derived alpha6 integrin-positive (iPSC-ITGA6(+)) cells with a di
85     Finally, we show that in vivo, NLGN1 and alpha6 integrin preferentially colocalize in the mature
86 s recruited to and activated specifically in alpha6 integrin receptor signaling complexes in the lens
87 tment of cells with laminin, a substrate for alpha6 integrin receptors, provided minimal inhibition.
88 regulating stromelysin-1 expression, whereas alpha6 integrins regulate cell motility.
89 stinguished by their unique co-expression of alpha6 integrin, Sca1 and CD200 surface proteins.
90                 Here we investigated whether alpha6 integrin signals upstream to this IGF-1R-mediated
91 ses and primary lens cell cultures following alpha6 integrin siRNA knockdown, we show that IGF-1R act
92                                          The alpha6 integrin subunit can be expressed as both alpha6b
93      I studied the expression pattern of the alpha6 integrin subunit during the early development of
94 s receptors for fertilin beta, since an anti-alpha6 integrin subunit monoclonal antibody, GoH3, has b
95                    Inhibiting alpha3 but not alpha6 integrin subunit using blocking antibodies or sma
96 grin subunit, oral pemphigoid sera recognize alpha6 integrin subunit, and anti-epiligrin cicatricial
97 gs from cultured ovaries of mice lacking the alpha6 integrin subunit, we found that the fertilization
98 disintegrin loop of fertilin beta and by the alpha6 integrin subunit.
99 combination of antibodies against alpha3 and alpha6 integrin subunits inhibit endothelial cell attach
100 ching was observed only when both alpha3 and alpha6 integrin subunits were inhibited.
101 e normally basal immunostaining of beta1 and alpha6 integrin subunits, pY, and paxillin was lost or m
102 lpha3beta1 integrin but not to the alpha2 or alpha6 integrin subunits.
103 n subunit, and sera of OP patients recognize alpha6 integrin throughout the clinical course.
104    First, cAMP accelerates redistribution of alpha6-integrin to the periphery of the acinus and thus
105                     At embryonic day (E)10.5 alpha6 integrin was expressed in the otic epithelium but
106 of alpha5 integrin was enhanced, and that of alpha6 integrin was inhibited.
107                   In this region of the lens alpha6 integrin was uniquely localized along the cell-ce
108 trates, whereas mutant keratinocytes lacking alpha6 integrin were relatively resistant to infection v
109                        Altered expression of alpha6 integrin, which forms a heterodimer with the beta
110  Along with binding to HSPGs, HPV16 binds to alpha6 integrins, which initiate further intracellular s
111                           The association of alpha6 integrin with the Triton-insoluble cytoskeleton i

 
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